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https://www.cognitivemedicinegroup.com 1 Neuroanatomy II: Systems, Pathways and Tracts Marc Norman, Ph.D., ABPP Amanda Gooding, Ph.D., ABPP Department of Psychiatry Neuropsychology Clinical Training Seminar (NCTS)

Neuroanatomy II: Systems, Pathways and Tractsmedicalneuropsych.com/.../CMG-NCTS-Neuroanatomy-II...CMG NCTS Neuroanatomy II - Compatibility Mode Created Date: 20200722021745Z

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Page 1: Neuroanatomy II: Systems, Pathways and Tractsmedicalneuropsych.com/.../CMG-NCTS-Neuroanatomy-II...CMG NCTS Neuroanatomy II - Compatibility Mode Created Date: 20200722021745Z

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Neuroanatomy II: Systems, Pathways and Tracts

Marc Norman, Ph.D., ABPPAmanda Gooding, Ph.D., ABPP

Department of PsychiatryNeuropsychology Clinical Training Seminar (NCTS)

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2Courtesy of Erin Bigler, Ph.D.

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Neostriatum or striatum

• Caudate + Putamen– Receives all input to BG– Most cortical input is

excitatory (glutamate)– Output is GABA

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Lentiform

• Globus Pallidus + Putamen

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BG Pic

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Connections

• Commisure• Faciculus

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Homonculus

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Limbic• Homeostasis• Olfaction• Memory• Emotion

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Getting� Limbic• Limbic Function Key Structure• Homeostasis, autonomic Hypothalamus & neuroendocrine control• Olfaction Olfactory Cortex• Memory Hippocampal Formation• Emotions and drives Amygdala

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Limbic System• Olfaction and regulation of emotions, memory, appetite

drives, and autonomic and neuroendocrine control• These areas are interconnected by a variety of

pathways, including the fornix- connecting the hippocampal formation to the hypothalamus and septal nuclei

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Limbic Structures• Medial and anterior

temporal lobes• Anterior insula• Inferior medial frontal

lobes• Hippocampal formation• Basal ganglia

• Cingulate gyri• Amygdala • Medial thalamic nuclei • Hypothalamus• Septal area• Brainstem

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Sensory• Posterior Column pathway - proprioception, vibratory,

fine touch• Anteriolateral- pain, temperature, and crude touch

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Spine: Everyone should get one

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Motor Neurons• Upper motor neurons

– From cortex to spinal cord or brainstem• Lower motor neuron

– Out of CNS via anterior spinal roots (cranial nerves) to muscles in periphery

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Crossover• Medulla/spinal cord junction• 85% of motor fibers cross over• Contralateral/ipsalateral

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Motor System (medial)

• Anterior Corticospinal tract• Vestibulospinal tract• Reticulospinal tract• Tectospinal tract

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Corticospinal• Major motor tract• Most important pathway - pyramidal tract• Voluntary movement• From cortex to anterior horn cells in spinal cord

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Corticospinal Tract

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Internal Capsule• Corticospinal/corticobulbar fibers form part of it• From cortex to brainstem = corticobulbar

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Rubrospinal Tract• Small, unclear clinically• Rubrospinal tract decussates in the ventral tegmentum at

the level of the midbrain to the red nucleus• A portion of the anterior corticospinal tract decussates at

the level of the cervical spinal cord, just below the Pyramid

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Rubrospinal

• May play role in decorticate posturing

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The End is Here• Repent, for the time is Nigh