OSTEOARTHRITIS

Textbook ReadingOSTEOARTHRITIS

PEMBIMBING:dr. Salman Al Wahabydr. Rangga Ariezadr. Fahroni Cahyono Winata

SUPERVISORdr. Karya Triko Biakto, Sp.OT (K) Spine

DIBAWAKAN DALAM RANGKA TUGAS KEPANITERAAN KLINIKBAGIAN ORTOPEDI DAN TRAUMATOLOGIFAKULTAS KEDOKTERAN UNIVERSITAS HASANUDDINMAKASSAR 2013

Muh. ZulfadliDevy LiantoHadrianiInayah S. AbubakarMuh. Nirsyad

1DefinitionOsteoarthritis (OA) is a chronic disorder of synovial joints in whichProgressive softening and disintegration of articular cartilage New growth of cartilage and bone at the joint margins (osteophytes)Cyst formation Sclerosis in the subchondral boneMild synovitis Capsular fibrosis.23PrevalenceThe primary or idiopathic type: more common in adult womenThe secondary type: more common in adult men.The knee is the most commonly affected joint, followed by hand and hip.

4Risk FactorTrauma OccupationObesity Family history5

6PATHOPHYSIOLOGYTheory 1Initiating event is fatigue fracture of collagen meshwork, followed by:Increased hydration of articular cartilageLoss of proteoglycans from matrixIncreased collagenolytic activity collagen lossPATHOPHYSIOLOGYPATHOLOGYCardinal features:Progressive cartilage desructionSubarticular cyst formationSclerosis of the surrounding boneOsteophyte formation9SITE OF SYMPTOMPSCentre either on one or two of the weightbearing joints:HipKneeInterphalangeal jointAny joint that has suffered a previous affliction10SYMPTOMPS AND SIGNS11Heberdens Nodes

12Laboratory ExaminationDoes not reveal any evidence of systemic diseaseSynovial fluid:Increased in mucin contentOA is non-inflammatory, with a white blood cell count