7
NEW HiSeq ® Series Production power Maximum throughput and lowest cost for production-scale genomics. Series includes the new HiSeq 3000 and HiSeq 4000 Systems. NEW NextSeq ® Series Flexible power Desktop speed and simplicity for everyday genomics. Series includes the NextSeq 500 and the new NextSeq 550 with cytogenomic array scanning. MiSeq ® Series Focused power Speed and simplicity for targeted and small- genome sequencing. Series includes the MiSeq and MiSeqDx Systems.* Compare our new systems with our product selector at www.illumina.com/power. Sequencing power for every scale. ©2015 Illumina, Inc. All rights reserved. NEW HiSeq X Series Population power Maximum throughput and low cost population- and production-scale human whole-genome sequencing. Series includes the HiSeq X Ten and the new HiSeq X Five Systems. FOR RESEARCH USE ONLY *MiSeqDx is a 510(k) cleared, CE-marked instrument. See instructions for use. Power your next big breakthrough.

Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

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Page 1: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

NEW

HiSeq® Series

Productionpower

Maximum throughput

and lowest cost for

production-scale

genomics. Series

includes the new

HiSeq 3000 and

HiSeq 4000 Systems.

NEW

NextSeq® Series

Flexiblepower

Desktop speed

and simplicity for

everyday genomics.

Series includes the

NextSeq 500 and the

new NextSeq 550

with cytogenomic

array scanning.

MiSeq® Series

Focusedpower

Speed and simplicity

for targeted and small-

genome sequencing.

Series includes the MiSeq

and MiSeqDx™ Systems.*

Compare our new systems with our product selector at www.illumina.com/power.

Sequencing power for every scale.

©2015 Illumina, Inc. All rights reserved.

NEW

HiSeq X™Series

Populationpower

Maximum throughput

and low cost

population- and

production-scale

human whole-genome

sequencing. Series

includes the

HiSeq X Ten and the

new HiSeq X Five

Systems.

FOR RESEARCH USE ONLY

*MiSeqDx™ is a 510(k) cleared, CE-marked instrument. See instructions for use.

Power your next bigbreakthrough.

Page 2: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

Promoting engineering, encouraging engineeringeducation, recognizing achievements that improveour lives.

Ohio University thanks late alumnus Fritz Russ andhis wife, Dolores, for creating the $500,000 RussPrize with an endowment to the University.We’reproud to steward their vision in collaboration withthe National Academy of Engineering.

www.ohio.edu/engineering/russ-prizeRuss College of Engineering

and Technology

The 2015 National Academy of Engineering

Fritz J. and Dolores H. Russ Prize

Creators of good:

DID YOUHEAR?Thanks to them,she does.

2015 Russ Prize recipients

Developers of the cochlear implant

• Graeme M. Clark

• Erwin Hochmair

• Ingeborg J. Hochmair

• Michael M.Merzenich

• Blake S.Wilson

Page 3: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

The Next Generation of

DNA Assembly and Cloning

NEW ENGLAND BIOLABS®, NEB® and NEBUILDER® are registered trademarks of New England Biolabs, Inc.

GIBSON ASSEMBLY® is a registered trademark of Synthetic Genomics, Inc.

* While supplies last. Offer valid in the US only. Limit one sample per customer.

NEBuilder® HiFi

DNA AssemblyThe next generation of DNA assembly andcloning has arrived. With NEBuilder HiFi DNAAssembly, you’ll enjoy virtually error-free joiningof DNA fragments. More efficient assemblyis now possible, even with larger fragments,low inputs, or 5´- and 3´-end mismatches.Additionally, use NEBuilder HiFi to bridge twodsDNA fragments with a ssDNA oligo. Save timewith less screening or re-sequencing, and benefitfrom no licensing fee requirements from NEBwhen choosing NEBuilder products.

Request a free sample*

at www.NEBuilderHiFi.com

Total fragmentsassembled

0

20

40

Fragment size

Vector size

Total size (kb)

60

80

100

NEBuilder HiFi DNA Assembly Master Mix (NEB #E2621)

Gibson Assembly Master Mix (NEB #E2611)

PercentCorrect

2

A

3 kb

5.4 kb

8.4

10/10 10/10

2

B

210 bp

7.7 kb

7.9

3/35/5

6

F

5 x 1 kb frags.

3.3 kb

8.3

11/12

1/10

3

E

450 bp + 250 bp

7 kb

7.7

12/12

5/8

2

D

3 kb

2.1 kb

5.5

10/10

7/10

2

C

210 bp

7.7 kb

7.9

5/5

1/4

NEBuilder HiFi DNA Master Mix offers improved fidelity

over Gibson Assembly Master Mix

Fidelity of assembled products was compared between NEBuilder HiFI DNA Assembly Master Mix

(NEB #E2621) and Gibson Assembly Master Mix (NEB #E2611). Experiments were performed

using the various fragment and vector sizes, following suggested protocols. Experiments B and C vary

because sequences of fragments are different. Experiments D and F were performed with fragments

containing 3´-end mismatches.

Page 4: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

CALL FOR PAPERSAbstract Submission Opens May 18, 2015 | Abstract Submission Deadline June 18, 2015

506 Keystone Drive • Warrendale, PA 15086-7573

Tel 724.779.3003 • Fax 724.779.8313

[email protected] • www.mrs.org

Don’t Miss These Future MRS Meetings!2016 MRS Spring Meeting & Exhibit

March 28 - April 1, 2016

Phoenix, Arizona

2016 MRS Fall Meeting & Exhibit

November 27 - December 2, 2016

Boston, Massachusetts

T. John Balk University of Kentucky

Ram Devanathan Pacifc Northwest National Laboratory

George G. Malliaras Ecole des Mines de St. Etienne

Larry A. Nagahara National Cancer Institute

Luisa Torsi University of Bari “A. Moro”

Meeting Chairs

ENERGY AND SUSTAINABILITY

LL Materials and Architectures for Safe and Low-Cost

Electrochemical Energy Storage Technologies

MM Advances in Flexible Devices for Energy Conversion and Storage

NN Thin-Film and Nanostructure Solar Cell Materials and Devices

for Next-Generation Photovoltaics

OO Nanomaterials-Based Solar Energy Conversion

PP Materials, Interfaces and Solid Electrolytes for High Energy Density

Rechargeable Batteries

QQ Catalytic Materials for Energy

RR Wide-Bandgap Materials for Energy EfRciency—

Power Electronics and Solid-State Lighting

SS Progress in Thermal Energy Conversion—

Thermoelectric and Thermal Energy Storage Materials and Devices

THEORY, CHARACTERIZATION AND MODELINGTT Topology in Materials Science—

Biological and Functional Nanomaterials, Metrology and Modeling

UU Frontiers in Scanning Probe Microscopy

VV In Situ Study of Synthesis and Transformation of Materials

WW Modeling and Theory-Driven Design of Soft Materials

XX Architected Materials—Synthesis, Characterization, Modeling and Optimal Design

YY Advanced Atomistic Algorithms in Materials Science

ZZ Material Design and Discovery via Multiscale Computational Material Science

AAA Big Data and Data Analytics for Materials Science

BBB Liquids and Glassy Soft Matter—Theoretical and Neutron Scattering Studies

CCC Integrating Experiments, Simulations and Machine Learning to Accelerate

Materials Innovation

DDD Lighting the Path towards Non-Equilibrium Structure-Property Relationships

in Complex Materials

X Frontiers of Material Research

A Engaged Learning of Materials Science and Engineering

in the 21st Century

BIOMATERIALS AND SOFT MATERIALSB Stretchable and Active Polymers and Composites

for Electronics and Medicine

C Tough, Smart and Printable Hydrogel Materials

D Biolological and Bioinspired Materials in Photonics and Electronics—

Biology, Chemistry and Physics

E Engineering and Application of Bioinspired Materials

F Biomaterials for Regenerative Engineering

G Plasma Processing and Diagnostics for Life Sciences

H Multifunctionality in Polymer-Based Materials, Gels and Interfaces

I Nanocellulose Materials and Beyond—

Nanoscience, Structures, Devices and Nanomanufacturing

J Wetting and Soft Electrokinetics

K Materials Science, Technology and Devices for Cancer Modeling,

Diagnosis and Treatment

L Nanofunctional Materials, Nanostructures and Nanodevices

for Biomedical Applications

NANOMATERIALS AND SYNTHESISM Micro- and Nanoscale Processing of Materials for Biomedical Devices

N Magnetic Nanomaterials for Biomedical and Energy Applications

O Plasmonic Nanomaterials for Energy Conversion

P Synthesis and Applications of Nanowires and Hybrid 1D-0D/2D/3D

Semiconductor Nanostructures

Q Nano Carbon Materials—1D to 3D

R Harsh Environment Sensing—Functional Nanomaterials

and Nanocomposites, Materials for Associated Packaging

and Electrical Components and Applications

MECHANICAL BEHAVIOR AND FAILURE OF MATERIALS

S Mechanical Behavior at the Nanoscale

T Strength and Failure at the Micro- and Nanoscale—

From Fundamentals to Applications

U Microstructure Evolution and Mechanical Properties

in Interface-Dominated Metallic Materials

V Gradient and Laminate Materials

W Materials under Extreme Environments (MuEE)

Y Shape Programmable Materials

ELECTRONICS AND PHOTONICS

Z Molecularly Ordered Organic and Polymer Semiconductors—

Fundamentals and Devices

AA Organic Semiconductors—Surface, Interface and Bulk Doping

BB Innovative Fabrication and Processing Methods for Organic

and Hybrid Electronics

CC Organic Bioelectronics—

From Biosensing Platforms to Implantable Nanodevices

DD Diamond Electronics, Sensors and Biotechnology—

Fundamentals to Applications

EE Beyond Graphene—2D Materials and Their Applications

FF Integration of Functional Oxides with Semiconductors

GG Emerging Materials and Platforms for Optoelectronics

HH Optical Metamaterials—

From New Plasmonic Materials to Metasurface Devices

II Phonon Transport, Interactions and Manipulations

in Nanoscale Materials and Devices—Fundamentals and Applications

JJ Multiferroics and Magnetoelectrics

KK Materials and Technology for Non-Volatile Memories

2015 FALL MEETING & EXHIBIT

November 29 – December 4, 2015 | Boston, Massachusetts

www.mrs.org/fall2015

The MRS/E-MRS Bilateral Conference on Energy will be comprised

of the energy-related symposia at the 2015 MRS Fall Meeting.

Page 5: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

1378 20 MARCH 2015 • VOL 347 ISSUE 6228 sciencemag.org/products SCIENCE

LIFE SCIENCE TECHNOLOGIESNEW PRODUCTS: GENERAL LAB EQUIPMENT

Produced by the Science/AAAS Custom Publishing Office

Ultracentrifuge

A new ultracentrifuge combines speed

with safety and ergonomics, allowing

researchers to easily protect samples

while achieving reliable and consistent

results. The Sorvall WX+ ultracentrifuge

features an intuitive color LCD touch-

screen to keep programming simple and

easy to navigate. Designed to accom-

modate a multiple-user environment,

the Sorvall WX+ ultracentrifuge monitors

run data with optional Log Manager

software that recalls past operating pa-

rameters with up to 5,120 cases of re-

corded histories to assist with GMP/GLP

compliance. In addition, the Sorvall WX+

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performance in a small footprint to maxi-

mize space in the lab; lightweight and

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rotors; automatic tube balancing com-

pensation, which accelerates sample

preparation by allowing visual sample

balancing up to 5 mm; and a self-locking

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that the rotor is automatically and se-

curely locked.

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����#��$������#�������

UV Spectrophotometer

Improved optical characterization sys-

tems are now available for spectral mea-

surements from the vacuum ultraviolet

to the near infrared. The vacuum ultra-

violet universal spectrophotometer is an

optical test system optimized for emit-

ting samples like phosphors or photo-

and electroluminescent crystals. It can

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working range, 120 nm to 2.2 µm. Options are available to extend

the range even more. The user-friendly sample chamber includes

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tive detection. It can operate purged or under vacuum and can

interface to commercial cryogenic and heated sample mounts.

Auxiliary ports are in the sample area for addition of HV leads for

electrical excitation, auxiliary sample by X-ray sources or con-

���#����"�"��$ ������!#�!#�#������$��������������$�������#���

spectrometers. The vacuum ultraviolet universal spectrophotom-

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Samples index while the system is under vacuum.

McPherson

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www.mcphersoninc.com

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations

are featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any

products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Clean Air Protection System

The Clean Air Protection (CAP) system

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Filtered clean air hood. The systemís

small design and price eliminates the

need to buy bulky and expensive lami-

nar fume hoods for their Microlab NIM-

BUS liquid handler. The system installs

and is up and running in less than one

hour. It uses Hamiltonís latest monitor-

ing and detecting technology, enabling

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�/����0�����!��&������������'�����()�

�!"#��./�0���/��������������/��0���./�0��

the CAP system delivers clean air to the

working environment. The monitoring

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creating a constant positive pressure

regardless of the door being open or

closed. The monitoring system also

features real-time temperature and

humidity display with built-in customer

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diagnostic sensor that alerts the user

�����/����./�0�������/��������������

Hamilton Robotics

��$������������������

www.hamiltoncompany.com

Automated Sample Thawing

System

The ThawSTAR automated sample

thawing system is a breakthrough

technology that addresses the ìlast

mileî in the cryopreservation process.

Utilizing STAR sensing technology,

ThawSTAR system tailors the thaw

���"��#��#�������������$��#�$�#���

of each frozen sample. ThawSTAR

technology integrates multiple detection

algorithms to ensure uniform thermal

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eliminating the subjectivity found in conventional thaw methods

that rely on human interpretation, such as swirling frozen vials in

water baths and rolling vials between hands. Users simply insert

a frozen vial and retrieve it when the vial is raised at the end of

the thaw cycle. The automatic release of the vial coupled with

built-in audio and visual alarms allow users to quickly retrieve

thawed vials for downstream processing. ThawSTAR thawing

system was engineered to deliver results similar to those achieved

�����#��������������� ���#�$���#� ��!#���#��$��$��!����"�#������

standardization built in.

BioCision

��2�������# ��"����� ��

www.biocision.com

50 µL Electronic Pipettes

The popular VIAFLO II electronic pipette

range has been expanded to include the

�������)*�����0����������2���10���00�1���

gap between the 0.5ñ12.5 µL and 5ñ125

)*�2���� �+�������0��0����2����0��������

�������� ��������0�,'&�*(�''�����11���

the new models deliver optimized preci-

sion pipetting in the volume range of

2ñ50 µL. The VIAFLO II multichannel

electronic pipette range combines ul-

tralightweight design and unsurpassed

operational comfort enabling users to

���2�����!����������1���2���2-��������-

ronment. VIAFLO II electronic pipettes

1���1��2���1��'+�%./&$������2��������

GripTip pipette tips form the perfect pi-

petting system. GripTips snap into place

��1��������0�1���0���������21���2��������

a secure connection. GripTips never

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resulting in superior accuracy and high

precision.

INTEGRA Biosciences

��2������������"������

www.integra-biosciences.com

Page 6: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

Stockholm in the second week of December is a special place. The city is alive

with excitement as it welcomes and celebrates the new Nobel Laureates at the

annual Nobel Prize ceremony.

If you are a recent PhD graduate you could be here too, and receive a rather

special prize yourself.

Te journal Science & SciLifeLab have established Te Science & SciLifeLab Prize forYoung Scientists, to recognize and reward excellence in PhD research and support youngscientists at the start of their careers. It’s about bright minds, bright ideas and bright futures.

Four winners will be selected for this international award.Tey will have their essays publishedin the journal Science and share a new total of 60,000 USD in prize money. Te winnerswill be awarded in Stockholm, in December, and take part in a unique week of eventsincluding meeting leading scientists in their felds.

“Te last couple of days have been exhilarating. It has been an experience of a lifetime.Stockholm is a wonderful city and the Award winning ceremony exceeds my wildest dreams.”–Dr. Dan Dominissini, 2014 Prize Winner

Who knows, Te Science & SciLifeLab Prize for Young Scientists could be a major step-ping stone in your career and hopefully one day, during Nobel week, you could be visitingStockholm in December once again.

Te 2015 Prize is now open. Te deadline for submissions is August 1, 2015.Enter today: www.sciencemag.org/scilifelabprize

Te 2015 Prize categories are:

• Cell and Molecular Biology

• Ecology and Environment

• Genomics and Proteomics

• Translational Medicine

For over 130 years the journal Science hasbeen the world’s leading journal of originalscientifc research, global news and commentary.

SciLifeLab is a collaboration among fouruniversities in Stockholm and Uppsala,Sweden, and is a national center formolecular biosciences with focus on healthand environmental research.

Tis prize is made possible with the kindsupport of the Knut and Alice WallenbergFoundation.

Will you be inStockholm thisDecember?(If you have a recent PhD you could be.)

Photo:HenrikTrygg/imagebank.sweden.se

Page 7: Power your next big breakthrough.€¦ · BioCision 2 # ˙ "ˆ˙ ˆ˙ ˝ 50 µL Electronic Pipettes The popular VIAFLO II electronic pipette range has been expanded to include the

For Research Use Only. Not For Use In Diagnostic Procedures.

© 2015 Cell Signaling Technology, Inc. Cell Signaling Technology, CST, and XP are trademarks of Cell Signaling Technology, Inc.

Learn more. www.cellsignal.com/labexpectations

WE DO ALL THIS, SO

YOU DON’T HAVE TO.

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