Risk Assessment and Risk Assessment and Monitoring for Monitoring for Environmental Environmental

Chemicals Chemicals

Prachathipat PongpinyoPrachathipat Pongpinyo

THAILANDTHAILAND

Researh and development of Researh and development of material in agriculture such material in agriculture such as soil, water and fertilizeras soil, water and fertilizer

Analysis serviceAnalysis service Consult and certified the Consult and certified the

other laboatoriesother laboatories Research and study in Research and study in

nuclear agrochemicalnuclear agrochemical Cooperate with another Cooperate with another

instituteinstitute

Purpose for attending this Purpose for attending this coursecourse Gain knowledge of Risk Gain knowledge of Risk

AssessmentAssessment Relates to my workRelates to my work To know more analysis To know more analysis

methodsmethods

What I have studied???What I have studied???

““Silent Spring” & “Our Stolen Silent Spring” & “Our Stolen Future”Future”

Endocrine Disrupting ChemicalsEndocrine Disrupting Chemicals Naturally or Synthesis substancesNaturally or Synthesis substances Effect to humanEffect to human Can change sex in some speciesCan change sex in some species Concentrate through the food chainConcentrate through the food chain

Food SafetyFood Safety Calculate by Acceptable Daily Calculate by Acceptable Daily

Intake value (ADI)Intake value (ADI) Study of toxicity of each Study of toxicity of each

substancessubstances Pesticide safety evaluation Pesticide safety evaluation

committeecommittee Endocrine Disruptor suspected Endocrine Disruptor suspected

pesticidepesticide

Maximum Residue Limit (MRLs)Maximum Residue Limit (MRLs) Related to the ADI valueRelated to the ADI value Set up for each pesticidesSet up for each pesticides

Good Agricultural Practice (GAP)Good Agricultural Practice (GAP) Decrease the effect of pesticideDecrease the effect of pesticide Reduce the dosage volumeReduce the dosage volume More effective controlMore effective control

Safety assessment of pesticideSafety assessment of pesticide How to conserve the How to conserve the

environment…environment…

Dioxins, PCBs, CFCDioxins, PCBs, CFC

Remain in the environment Remain in the environment for a long timefor a long time

Accumulated in the body of Accumulated in the body of living creatureliving creature

Concentrate through the Concentrate through the food chainfood chain

How to conserve and How to conserve and sustain the environmentsustain the environment

Registration of new Registration of new pesticidespesticides Eco-toxicological effect Eco-toxicological effect

studystudy Environment fate studyEnvironment fate study Ecological risk assessmentEcological risk assessment

toxicity exposure ratiotoxicity exposure ratio Study of distribution, effect Study of distribution, effect

and fate of man-made and fate of man-made organic substancesorganic substances

Bio accumulation in the Bio accumulation in the environmentenvironment Accumulation of Accumulation of

Organochlorines in river water Organochlorines in river water and sea waterand sea water

Accumulation of Accumulation of Organochlorines in stripped Organochlorines in stripped dolphindolphin

Accumulation of Accumulation of Organochlorines in plankton in Organochlorines in plankton in Osaka bay areaOsaka bay area

Treatment of agro-Treatment of agro-chemical compoundschemical compounds Degradation of Degradation of

Organophosphorus by bacteriaOrganophosphorus by bacteria Isolation of TCP degrading Isolation of TCP degrading

bacteria from river water and bacteria from river water and properties of bacteriaproperties of bacteria

Degradation of TBT by the Degradation of TBT by the bacteria in the river water, sea bacteria in the river water, sea water and isolation of TBT water and isolation of TBT degrading bacteria from the degrading bacteria from the river water.river water.

Solid waste managementSolid waste management

IncinerationIncineration Reduce massReduce mass DeodorizationDeodorization DetoxificationDetoxification

Exhaust treatment is require for Exhaust treatment is require for eliminate particulate matter eliminate particulate matter such as HCl, SOsuch as HCl, SO22, NO, NO22, dioxins , dioxins and heavy metalsand heavy metals

Alternative way to reduce Alternative way to reduce dioxinsdioxins Control the temperature to Control the temperature to

above 850Cabove 850C Activated carbonActivated carbon Active coke reactorActive coke reactor Dioxin catalystDioxin catalyst

Consideration of waste Consideration of waste management policymanagement policy Current status of waste Current status of waste

treatment/disposaltreatment/disposal Responsibility of wasteResponsibility of waste Treatment and disposal Treatment and disposal

technique for hazardous technique for hazardous wastewaste

Source of emissionSource of emission

Metabolism of pesticide in Metabolism of pesticide in plant studyplant study Extrapolate toxicity effect in Extrapolate toxicity effect in

human from animals studyhuman from animals study in vivo in vivo study use labeled study use labeled

compound and inject into animalcompound and inject into animal Pesticide and metabolite have Pesticide and metabolite have

different toxicity propertiesdifferent toxicity properties in vitro study is for the in vitro study is for the

metabolism study such as a cell metabolism study such as a cell cultureculture

Soil StudySoil Study

Prediction half-life of Prediction half-life of pesticidepesticide

Clay type hold more pesticide Clay type hold more pesticide than sandy soilthan sandy soil

Leaching test; the herbicide Leaching test; the herbicide was contained in mineral soil was contained in mineral soil than volcanic ash soilthan volcanic ash soil

NONO33 caused a caused a meehemoglobinemia diseasemeehemoglobinemia disease

Practice/ObservationPractice/Observation

GC, GC-MSGC, GC-MS LC, LC-MSLC, LC-MS UV-Vis spectophotometerUV-Vis spectophotometer Portable devices such as pH, Portable devices such as pH,

DO, CO, CODO, CO, CO22, conductivity, conductivity AASAAS

Hyogo Prefecture Technology Center on Hyogo Prefecture Technology Center on Agriculture, Forestry and Fisheries Agriculture, Forestry and Fisheries (HPTCAFF)(HPTCAFF)

Analysis of heavy metals in soil Analysis of heavy metals in soil and compostand compost

Nitrate analysis in vegetablesNitrate analysis in vegetables Water quality assessment in Water quality assessment in

agricultureagriculture Study of effect of pesticide on Study of effect of pesticide on

soil microbial biomasssoil microbial biomass Pesticide residue analysisPesticide residue analysis Rapid analysisRapid analysis

KOBE Quarantine StationKOBE Quarantine Station

Simultaneous analysis of Simultaneous analysis of pesticide residue in fruits and pesticide residue in fruits and vegetablesvegetables

Simultaneous analysis of Simultaneous analysis of pesticide residue in Cereals, pesticide residue in Cereals, Beans and SeedsBeans and Seeds

GC-MS for screening and fast GC-MS for screening and fast analysisanalysis

Principle of Good Laboratory Principle of Good Laboratory Practice (GLP)Practice (GLP)

Confirm the result with GCConfirm the result with GC

Hyogo Prefectural Institute of Public Hyogo Prefectural Institute of Public Health and Environmental Sciences Health and Environmental Sciences (HPIPHES)(HPIPHES)

PCBs ELISA kitPCBs ELISA kit Analysis of PCBs in sediment Analysis of PCBs in sediment

samplesample Comparison analysis of pesticide Comparison analysis of pesticide

in water between SPE and LLEin water between SPE and LLE Analysis of heavy metals in Analysis of heavy metals in

industrial wasteindustrial waste Inspection kit for CN, NHInspection kit for CN, NH33 in in

waterwater

Multi component simultaneous Multi component simultaneous pesticide analysis in domestic pesticide analysis in domestic and imported food by GC-MS and and imported food by GC-MS and LC-MSLC-MS

Total hardness of natural Total hardness of natural drinking water drinking water related to taste related to taste of drinking waterof drinking water

Analysis of potassium Analysis of potassium permanganatepermanganate

Measuring of mass concentration Measuring of mass concentration of ambient particulate matters of ambient particulate matters (PM(PM1010))

KOBE UniversityKOBE University

ELISA practice and analysis ELISA practice and analysis techniquetechnique

ELISA kit; Tube and ELISA kit; Tube and Microplate typesMicroplate types

ELISA analysis for pesticide ELISA analysis for pesticide (Alachlor)(Alachlor)

Useful Subject to solve the Useful Subject to solve the problem in Thailandproblem in Thailand Pesticide registration Pesticide registration

systemsystem Analysis of environmental Analysis of environmental

samplesample Good Agricultural PracticeGood Agricultural Practice Good Laboratory PracticeGood Laboratory Practice Waste management Waste management

Action PlanAction Plan

Report to the Department of Report to the Department of AgricultureAgriculture

Implement of GLPImplement of GLP Propose for implementation and Propose for implementation and

adaptationadaptation ReviewReview TrainingTraining Propose for up-to-date Propose for up-to-date

instrumentinstrument

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SAWASDEESAWASDEE