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    A STUDY OF CORRELATION OF

    FOOT LENGTH AND

    GESTATIONAL MATURITY INNEONATES

    By

    Dr. DEEPA S., MBBS

    Dissertation S!"itte# to t$e

    Ra%i& Gan#$i Uni&ersity o' Hea(t$ S)ien)es, *arnata+a, Bana(ore

    In -artia( '('i(("ent

    o' t$e reire"ents 'or t$e #eree o'

    DOCTOR OF MEDICINEIn

    PAEDIATRICS

    Un#er t$e i#an)e o'

    Dr. /I0AY*UMAR B., MD,DCHPro'essor

    DEPARTMENT OF PAEDIATRICS

    MYSORE MEDICAL COLLEGE AND RESEARCH INSTITUTE

    MYSORE1234 456

    APRIL 5464

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    RA0I/ GANDHI UNI/ERSITY OF HEALTH SCIENCES,

    *ARNATA*A, BANGALORE

    DECLARATION BY THE CANDIDATE

    I hereby declare that this dissertation entitled 7A STUDY OF CORRELATION

    OF FOOT LENGTH AND GESTATIONA L MATURITY IN NEONATES8 is a

    bonafide and genuine research work carried out by me under the guidance of

    Dr. /I0AY*UMAR B., MD,DCH, Professor, Department of Paediatrics, Mysore

    Medical College and Research Institute, Mysore.

    I have not submitted this previously to this niversity or any other niversity for

    the award of any degree or diploma.

    Date! Dr. DEEPA S.

    Postgraduate in PaediatricsPlace! Mysore Mysore Medical College and Research Institute,

    Mysore

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    iii

    AY*UMAR B., MD,DCH

    CERTIFICATE BY THE GUIDE

    "his is to certify that the dissertation entitled 7A STUDY OF CORRELATION

    OF FOOT LENGTH AND GESTATIONA L MATURITY IN NEONATES8 is a

    bonafide research work done by Dr. DEEPA S. , in partial fulfillment of the

    re#uirement for the degree of Doctor of Medicine in Paediatrics.

    I have immense pleasure in forwarding this dissertation to Ra$iv %andhi

    niversity of &ealth 'ciences, (arnataka, )angalore.

    Date! Dr. /I0Professor

    Place! Mysore Department of Paediatrics,

    Mysore Medical College and Research Institute,

    Mysore.

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    Dr. B. *RISHNAMURTHY, MD,DCH Dr. D. /EN*ATESHA, MD

    Professor and &ead Director*Dean,

    Department of Paediatrics, Mysore Medical College and

    Mysore Medical College and Research Institute,

    Research Institute, Mysore.

    Mysore.

    Date! Date!

    Place! Mysore Place! Mysore

    iv

    ENDORSEMENT BY

    THE HEAD OF THE DEPARTME NT AND DIRECTOR9DEAN

    "his is to certify that the dissertation entitled 7A STUDY OF CORRELATION OF

    FOOT LENGTH AND GESTATIONAL MATURITY IN NEONATES8 is a

    bonafide and genuine research work done by Dr. DEEPA S. under the guidance of

    Dr. /I0AY*UMAR B., MD,DCH, Professor, Department of Paediatrics, Mysore

    Medical College and Research Institute, Mysore.

    I have immense pleasure in forwarding this dissertation to Ra$iv %andhi

    niversity of &ealth 'ciences, (arnataka, )angalore.

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    v

    RA0I/ GANDHI UNI/ERSITY OF HEALTH SCIENCES,

    *ARNATA*A, BANGALORE

    COPYRIGHT De)(aration

    !yt$e )an#i#ate

    I hereby declare that the Ra$iv %andhi niversity of &ealth 'ciences, (arnataka,

    )angalore shall have the rights to preserve, use and disseminate this dissertation in print

    or electronic format for academic*research purpose.

    Date! Dr. DEEPA S.

    Postgraduate in Paediatrics

    Place! Mysore Mysore Medical College and Research Institute,

    Mysore

    RA0I/ GANDHI UNI/ERSITY OF HEALTH SCIENCES

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    vi

    AC*NO:LEDGEMENTS

    I owe a great debt of gratitude to my respected teacher and guide,

    Dr. /i%ay+"ar B., Professor, Department of Paediatrics, Mysore Medical College and

    Research Institute, Mysore for his advice, appropriate guidance, constant supervision and

    encouragement provided to me throughout the period of this study. I e+press my deep

    sense of gratitude to him for his utmost patience and keen interest in completing my

    dissertation successfully.

    I wish to thank with due respect and deep gratitude to Dr. B. *ris$na"rt$y

    , Professor and &ead, Department of Paediatrics, Mysore Medical College and Research

    Institute, Mysore, for his precious timely suggestions and advice that helped me to a great

    e+tent.

    I am e+tremely grateful and wish to e+tend my sincere thanks to Dr. S#$a

    R#ra--a and Dr. *"ar G.M. , Professors, Department of Paediatrics, Mysore

    Medical College and Research Institute, Mysore, for their valuable guidance and

    suggestions.

    I e+press my deep sense of gratitude and sincere thanks to Dr. Sa&it$a M.R.

    , ssistant Professor, for her invaluable help in preparing this dissertation.

    I wish to e+press my sincere regards to Dr. Us$a+iran C.B. and Dr. Man%nat$

    , -ecturers, for their kind cooperation and timely help.

    I wish to thank Dr. S$ai(a%a B. , 'enior 'pecialist, for her help and support.

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    I also e+press my gratitude to the Dire)tor9Dean, Mysore Medical College and

    Research Institute S-erinten#ent, Cheluvamba &ospital and the /thical Committee for

    allowing me to conduct this study.

    I am most e+tremely thankful to my parents and husband, for their moral support

    during the study period.

    I wish to thank Dr. Lan)y D;So

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    LIST OF ABBRE/IATIONS

    % 1 ppropriate for gestational age

    )PD 1 )iparietal diameter

    )2t 1 )irth weight

    CC 1 Chest circumference

    C&- 1 Crown heel length

    cm3s4 1 Centimeter3s4

    0- 1 0oot length

    g 1 %ram

    % 1 %estational age

    &C 1 &ead circumference

    IC 1 Intensive care unit

    IMR 1 Infant mortality rate

    I%R 1 Intra uterine growth retardation

    (cal 1 (ilocalories

    (g 1 (ilogram

    -)2 1 -ow birth weight

    -% 1 -arge for gestational age

    -MP 1 -ast menstrual period

    p 1 Probability value

    P&C 1 Primary health centre

    r 1 Correlation coefficient

    '% 1 'mall for gestational age

    ") 1 "raditional birth attendants

    '% 1 ltrasonography

    5-)2 1 5ery low birth weight

    2&6 1 2orld &ealth 6rganisation

    viii

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    ABSTRACT

    BAC*GROUND AND OB0ECTI/ES

    'ince decades attempts have been made to find an alternative measurement for

    gestational age and birth weight estimation of the newborns. ppropriate and timely care

    of a low birth weight newborn is important but this is difficult in developing countries

    since most of the deliveries are conducted at home where ade#uate facilities to weigh a

    newborn does not e+ist. 0oot length has been studied by various authors as pro+y

    measurement which can be measured easily in sick and preterm newborns. "his study

    was done to find correlation of foot length with gestational age and other anthropometric

    measurements 3birth weight, head circumference and crown heel length4.

    METHODOLOGY

    'tudy sample of 788 newborns were selected by simple random sampling

    techni#ue born at Cheluvamba &ospital attached to Mysore Medical College and

    Research Institute, Mysore from December 988: to ;ovember 9887. )abies with limb

    deformities were e+cluded from the study group. %estational age was assessed by

    ;ew )allard score and babies were grouped into term, preterm and post

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    RESULTS

    In the study male newborns were >?@ and female A:@. In the study group

    98? babies 39>.A@4 were low birth weight babies. >98 newborns 3B>@4 had birth weight

    in the range of 9.>

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    P % 6.

    I. ODU 0 E

    9. Dl/ A

    OF

    s. ST

    :.

    !7.

    E8.

    i4 )--RD CORE 1

    ij) 5) CO GO

    iii) E

    iv4 "& PP/D E

    ) TER HART E

    +i

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    LIST OF TABLES

    Ta!(e

    No.

    Tit(e Pae

    No.

    6 Identifiable causes of preterm birth 6>

    5 0actors often associated with intrauterine growth retardation 5?

    @ 'e+ distribution of babies based on their birth weight 2

    Descriptive statistics of birth weight under different categories 2?

    2

    Distribution of babies according to their maturity and weightDescriptive statistics of head circumference for different groups of

    babies>

    64

    66

    Descriptive statistics of crown heel length for different groups of

    babies

    Correlation between foot length and other variables for preterm %

    34

    36

    65 Correlation between foot length and other variables for preterm '% 3@

    6@ Correlation between foot length and other variables for term % 32

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    Ta!(e

    No.

    Tit(e Pae

    No.

    6 Correlation between foot length and other variables for term '% 33

    62 Correlation between foot length and other variables for term -% 3>

    6 Correlation between foot length and other variables for post

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    LIST OF FIGURES

    Fire

    No.Tit(e Pae

    No.

    6 "he vicious cycle of low birth weight babies in developing countries 5>

    5 ;ewborn maturity rating and classification 3;ew )allard 'core4 @

    @ 'liding calipers used for measuring foot length 26

    Demonstration of measurement of foot length using sliding caliper 26

    2 Demonstration of measurement of head circumference using a fle+ible, 25non Mean birth weight with respect to birth weight groups 2>

    64 Classification of newborns according to their maturity 4

    66 Classification of newborns according to their weight

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    1

    INTRODUCTION

    /arly in this millennium, India and ;ations around the world committed

    themselves to achieve the Millennium Development %oals. %oal factor aims to

    reduce under > mortality by 9*?rd

    between E8. "his means reducing

    under > mortality to ?B per E888 live births and the Infant Mortality Rate to

    9:*E888 live births. "oday, while there have been encouraging signs, IndiaHs IMR

    remains high at >7*E888 livebirths.

    "he most challenging part of infant mortality is the large proportion of

    new born deaths, contributing to an estimated BA@ of all infant deaths, mostly

    in the first week of life.E

    Ma$or causes of neonatal mortality are diseases

    associated with preterm birth, low birth weight babies3-)24 and lethal congenital

    anomalies.

    "hus birth weight is an important indicator of survival, future growth and

    overall development of the child. It is associated with socio

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    3

    "his alternative measurement should be easy to be conducted even by

    ine+perienced health care staff and should have a very little intra and inter

    observer variability.>

    "he techni#ue used for measuring such a parameter should

    be simple so that even an untrained health care staff can do the measurement

    reliably. 0oot length is one such parameter which can be measured easily in

    preterm and sick neonates without disturbing thebaby.

    "his study is being done to find a correlation between foot length,

    gestational age and other anthropometric measurements.

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    4

    OB0ECTI/ES

    E. "o study the correlation of foot length and gestational age among preterm,

    term and post

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    5

    RE/IE: OF LITERATURE

    Histori)a( As-e)ts

    In E7A, the first world health assembly recogni=ed the importance of

    prematurity as a worldwide cause of infant deaths and adopted an international

    definition of prematurity, i.e. a baby whose birth weight is less than 9>88 g. "he

    2&6 e+pert group on prematurity endorsed this international definition but

    reali=ed that it would not be applicable in each and every country.B

    In many parts of the world the international definition proved useful for

    separating off babies which re#uired some form of special care, but in other

    countries the use of this standard resulted in unusually high proportions of

    premature babies, many of whom were not born preterm and did not seem to

    re#uire any special care. "his led to local adoption of various low birth weight

    standards which created confusion and prevented comparisons.

    "he time for re88 gm and less at birth were born after ?: weeks of gestation but with a low

    birth weight. In view of the convincing evidence that many of the babies included

    in the international definition were not born prematurely, an e+pert committee on

    maternal and child health 32&6, EBE4 recommended that concept of

    prematurityH should give way to that of low birth weightH.

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    'ince decades many authors have studied the utility and reliability of

    anthropometric parameters as an alternative for gestational age and birth weight

    assessment.

    Parameters such as chest and arm circumference and length of the baby

    and its correlation with birth weight were analy=ed in a study done by

    ;ikorn Dusitsin.:

    "his study was done to find an alternative to birth weight

    measurement so that it can be used at primary health care level in developing

    countries like India, where ma$ority of births are conducted at home and the

    measurement of birth weight is very difficult due to nonB cm4 and a mid arm

    circumference of 7. cm which corresponded well with birth weight of 9.> kg and

    a home made measuring tape has been devised based on mid arm circumference to

    detect birth weights with cut off values for 9>88 g, 9888 g to 9>88 g and 9888 g in

    different shades of colour for illiterate birth attendants.9

    'harma K; et al concluded that gestational age had a good correlation with

    birth weight and crown heel length. "hey also concluded that birth weight had a

    very good correlation with mid arm circumference and chest circumference. "hey

    have suggested these measurements as an alternative to birth weight and

    gestational age assessment.7

    )hatia )D et al. concluded that there is a good

    correlation between arm circumference and birth weight.

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    7

    Dubowit= -M' et al. in E:8 described LClinical assessment of gestational

    age in the new born infant.E8

    )allard K- et al. described a simplified score of fetal

    maturation of newly born infantsEE

    and in EE published L;ew )allard score,

    e+panded to include e+tremely premature infants.E9

    ;eela K et al. in EE described usefulness of calf circumference as a

    measure for screening low birth weight infants.E?

    De

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    8

    Platt -D et al in their study described that the ultrasonic measurements of

    fetal foot length gave a reliable assessment of anatomical fetal or neonatal foot

    length and was highly correlated to the gestational age of the fetus.E7

    (umar %P et al. have reported that gestational age of the fetus can be

    estimated from hand and foot length. "hey found that the period of gestation in

    weeks can be obtained from foot length by multiplying foot length by ?.A7B? and

    adding 7.7BA.E

    &ern 2M et al. correlated fetal measurements, especially fetal foot length

    with fetal age, as measured by -ast Menstrual Period 3-MP4, for specimens

    obtained after dilatation and evacuation and abortion. 0etal measurements,

    including weight, knee

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    9

    especially when other parameters do not accurately predict gestational age as in

    conditions like hydrocephalus, anencephaly and short limb dysplasia.9?

    Mhaskar R et al in their study of fetuses in the age group E? to A9 weeks

    gestation demonstrated a strong correlation between foot length and gestational

    age.9A

    Daga 'R et al. have suggested foot length corresponding to ?A weeks

    gestational age as a cut

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    %ohil et al found significant relationship between foot length and other

    body parameters 3birth weight, crown heel length and head circumference4.

    &ighest correlation in preterm babies was with crown heel length and weight, and

    in term babies with head circumference. "hey concluded that foot length could be

    useful in deriving the surface area more accurately than from birth weight alone

    for the calculation of drug dosage and fluid re#uirements in preterms.?9

    Madhulika et al. studied E888 live born babies of various gestational ages

    to establish normal anthropometric limb standards in newborns. 5arious limb

    anthropometric measurements 3upper arm length, hand length, hand breadth, little

    finger length, leg length4 were taken and their correlation with gestational age was

    analy=ed. 0oot length correlated best with gestational age amongst all the

    measurements 3rG8.A4. "hey have suggested that limb standard can be of use in

    determining gestational age, intrauterine growth rate and early detection of various

    syndromes with abnormal skeletal growth rate as their characteristic features.??

    Merlob P et al. in their study have suggested lower limb anthropometry

    3total lower limb length, leg length and foot length to be helpful in evaluation of

    disproportionate short stature in neonatal skeletal dysplasia. "hese lower limb

    standards will help the clinician to discriminate unusual lengths and ratios in

    newborns.?A

    study was done by (ulkarni et al. to know the range of values for the

    foot length in infants from 9B

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    other anthropometric indices 3birth weight, length4 and foot is usually accessible

    for measurement even in preterms nursed in incubators.?>

    'hepard "& et al have described a scatter diagram correlating foot length

    and gestational age.?B

    /mbleton ;D et al in their study used foot length as a predictor of

    nasotracheal tube length. "hey found foot length to be a good predictor of

    nasotracheal distances than body weight, gestational age and head circumference.

    "hey have concluded foot length as a reliable and reproducible predictor of

    nasotracheal tube length and an e#uivalent predictor to birth weight estimation

    which can be very useful in sick unstable infants.?:

    Kohnson MP et al. in their study found that the 3legNarm length4*foot length

    ratio was significantly shortened for fetuses with trisomy 9E, on direct necropsy

    measurements.?7

    Droste ' et al. used ultrasonographic foot length measurement to generate

    regression lines for adrenal gland weight.?

    Malas M et al. studied about the growth of the upper 3width of the

    shoulder and the length of the arms, forearms and hands4 and lower 3width of iliac

    crest, knee condyles, feet, and heels and the length of the thighs, legs and feet4

    e+tremities of "urkish fetuses during the fetal period. 'tatistically significant

    correlations found between foot

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    mato M et al in EE did a study to compare foot length and

    intermamillary distance to gestational age assessment using obstetrical dates,

    physical criteria of )allard score and evaluation of anterior vascular capsule of the

    lens. "hey concluded that the appropriate use of biometric parameters in the early

    postnatal period can be used to improve assessment of gestational age in very low

    birth weight infants.AE

    Mer= / et al in their study have established age

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    is important. More accurate tables of these measurements allow for greater

    precision in correlating gestational duration and foot length.AA

    In a study done by 'hambhu 'haran 'hah et al., foot length was found to

    be best correlating with birth weight 3r G 8.9, p F 8.88E4 and foot length was

    recommended as a pro+y measurement to birth weight assessment.A>

    Mullany -C et al. conducted a study to compare the validity of chest

    circumference and foot length as surrogate anthropometric measures for

    identification of low birth weight and very low birth weight infants. "hey

    concluded that for identification of very low birth weight infants, foot length

    performed well and may be preferable to chest circumference as the former

    measure does not re#uire removal of infant clothes.AB

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    FETAL GRO:TH AND DE/ELOPMENTA:,A7

    "he most dramatic events in growth and development occur before birth.

    "hese changes are overwhelmingly somatic, i.e. the transformation of a single cell

    into an infant. "he uterus while offering a degree of protection is affected

    by social, psychological and environmental influences. "he comple+ interplay

    between these forces and the physical transformations occurring in

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    B. Feta( Perio#

    0rom th

    week onwards fetal somatic changes consist of increase in cell

    number and si=e and structural remodelling of several organ systems.

    )y E8th week, the face is recogni=ably human. "he midgut returns from the

    umbilical cord into the abdomen rotating counter

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    dendrites and the elaboration of synaptic connections continue at a rapid pace,

    making the central nervous system vulnerable to teratogenic or hypo+ic influences

    throughout gestation.

    BEHA/IOURAL DE/ELOPMENT

    Muscle contraction first appears around 7 weeks, soon followed by lateral

    fle+ion movements. )y E?

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    "he wide range of outcomes observed reflects the comple+ interactions

    among biologic and social risk and protective factors.

    INFANTS OF LO: BIRTH :EIGHT

    s per 2&6 criterion, a low birth weight baby is one with a birth weight

    of less than 9>88 g 3upto and including 9A g4 irrespective of the period of

    gestation. "his definition has less practical significance in countries like India as

    most -)2 infants are mature by gestation.

    INCIDENCE

    In accordance with 2&6 criterion for -)2 about ?8

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    A. In)i#en)e

    bout E8

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    B. Aetio(o,y

    "he mechanisms initiating normal labour are not clearly understood and

    much less are known about the factors that initiate labour before term. "here may

    be spontaneous onset of premature labour or it may be induced by the obstetrician

    to safeguard the interests of the mother or thebaby.

    S-ontaneos

    "he cause of premature onset of labour is uncertain in most instances. "he

    known causes include poor socio

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    21

    C. P$ysio(oi)a( Han#i)a-sA

    6. Centra( ner&os syste"

    "he immaturity of nervous system is e+pressed as inactivity and lethargy,

    poor cough refle+ and incoordinated sucking and swallowing in babies weighing

    less than E788 g or born before ?> weeks of gestation. Resuscitation difficulties at

    birth and recurrent apneic attacks are common. Retrolental fibroplasias due to

    o+ygen to+icity is limited to babies with a gestation of less than ?> weeks. 6n the

    other hand, they are more resistant to to+ic effects of hypo+ia as compared to the

    term babies. "hey are e+tremely vulnerable to develop intraventricular8,>E,>9

    Premature infants are vulnerable to a wide spectrum of morbidity.

    E. Developmental disability

    a. Ma$or handicaps 3cerebral palsy, mental retardation4

    b. 'ensory impairments 3hearing loss, visual impairment4

    c. Minimal cerebral dysfunction 3language disorders, learning

    disability, hyperactivity, attention deficit, behaviour disorders4.

    9. Retinopathy ofprematurity

    ?. Chronic lung disease

    A. Poor growth

    >. Increased rates of post neonatal illness and rehospitali=ation.

    B. Increased fre#uency of congenital anomalies.

    :. Increased risk of child abuse and neglect.

    II. INFANTS :HO ARE SMALL FOR GESTATIONAL AGE

    De'inition

    "here is no uniform definition of '%, although most reports define it as

    two standard deviation below the mean for gestational age or as below the tenth

    percentile. number of Lnormal birth curves have been defined using studies of

    large infantpopulations.>8

    5arious names have been applied to these infants, vi=. light

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    insufficiency syndrome, etc.?

    In developing countries three

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    dermatoglyphics. "heir cell population is also reduced, resulting in permanent

    mental and physical growth retardation.

    @. Mie# s"a(('orestationa( ae !a!ies

    "hey are the outcome of adverse intrauterine environmental influences

    operating from early or mid pregnancy. "hese infants, though small for the period

    of their gestation, neither look obviously malnourished or grossly hypoplastic.

    "hey show varying degrees of reduction in cell population and si=e.

    Ta!(e 5= Fa)tors o'ten asso)iate# it$ intraterine rot$ retar#ationA:

    6. Feta(

    Chromosomal disorders 3e.g. utosomal trisomies4

    Chronic fetal infections 3e.g. cytomegalic inclusion disease, congenital

    rubella, syphilis4

    Congenital anomalies syndrome comple+es

    Radiation in$ury

    Pancreatic hypoplasia

    Multiple gestation

    5. P(a)enta(

    Decreased placental weight or cellularity orboth

    Decrease in surface area

    5illous placentitis 3bacterial, viral,parasitic4

    Infarction

    bruption

    Previa

    "umour 3chorioangioma, hydatidiform mole4

    "win transfusion syndrome

    @. Materna(

    "o+emia

    &ypertension or renal disease, orboth

    &ypo+ia 3high altitude, cyanotic cardiac or pulmonary disease4

    Malnutrition or chronic illness

    'ickle cell anaemia and other hemoglobinopathies

    Drugs 3narcotics, alcohol, cigarettes, cocaine, antimetabolites4

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    'hort and light

    ndernourished mother

    3illiteracy,poverty4

    'mall 'mall

    boy girl

    Q 'mall uterus ;eglect and ill health

    Poor nutritional Poor nutrition during

    stores, anaemia, childhood

    fre#uentpregnancies

    -ack of schooling

    and education

    Poor adolescent

    growth spurt

    Fire 6= T$e &i)ios )y)(e o' (o !irt$ ei$t !a!ies in #e&e(o-in )ontriesA

    Cases

    0rom the table 9, it is obvious that cause may rest with the mother, placenta

    or the fetus itself. Infant with intrauterine growth retardation has small placenta

    but fetoplacental ratio is unaffected and varies between >.>!E to B!E

    6. Materna( Ma(ntritionA

    Relatively high incidence of small

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    affecting fetal growth. 'mall newborn baby of these mothers may grow up to

    become a small girl due to altered growth potential and e+posed to further

    deleterious effects of socio

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    demonstrated that supplementation of iron and folic acid during last trimester of

    pregnancy is associated with increased mean weight of the off

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    3. Birt$ or#er

    Primiparas have a higher percentage of -)2 babies than women of other

    parity. 6n the other hand, birth weight is also adversely affected in grand

    multipara women 3i.e. para ? and more4.A

    ?. Se

    0emale infants weigh lesser than male infants of comparable gestational

    age.

    >. Mis)e((aneos )ases

    a. Materna( s!stan)e a!se like smoking, tobacco chewing and alcohol

    consumption cause -)2 babies. "he incidence of low birth weight doubles if the

    pregnant woman smokes more than 98 cigarettes per day. If a pregnant woman

    chews A88 mg of tobacco everyday, the birth weight of the baby is reduced by

    upto >A9g compared to control women. If a mother consumes two alcoholic drinks

    everyday during pregnancy, the birth weight of the baby is reduced on an average

    by E>>g.A

    !. A(tit#e= ltitude is not a simple variable but involves cosmic radiation,

    decreased partial pressure of o+ygen, increased ultraviolet radiation, decreased

    humidity and temperature. &igher the altitude more the incidence of -)2.

    MANAGEMENT OF THE SGA INFANT AT BIRTH

    a. De(i&ery= /arly delivery is necessary if the risk to the fetus of remaining

    in utero is considered greater than the risks of prematurity. %enerally

    indications for delivery are arrest of fetal growth, fetal distress, andpulmonary

    maturity near term, especially in a mother with hypertension. If there is poor

    placental blood flow, the fetus may not tolerate labour and may re#uire

    caesarean delivery.

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    '% infants are at risk for perinatal problems and often re#uire speciali=ed

    care in the first few days of life. "herefore, if possible, delivery should occur at a

    centre with a high risk care nursery. "he delivery team should be prepared to

    manage fetal distress, perinatal depression, meconium aspiration, hypo+ia,

    hypoglycemia and heat loss.

    !. In t$e nrsery

    i Ne!orn ea"ination= "he infant should be evaluated for any of the causes

    listed in table 9 especially chromosomal abnormalities, malformations and

    congenital infection.

    6. Infants who had growth restriction due to factors influencing the last

    part of pregnancy 3e.g. maternal renal disease, pre

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    ii Pat$o(oi) ea"ination o' t$e -(a)enta 'or in'ar)tion or )on,enita(

    in'e)tion "ay !e $e(-'(.

    iii Genera((y sero(oi) s)reenin 'or )onenita( in'e)tion is not in#i)ate#

    n(ess $istory or ea"ination sests in'e)tion as a -ossi!(e )ase.

    i& E&a(ation 'or t$e 'o((oin )o"-(i)ations re(ate# to IUGR is #one an#

    a--ro-riate(y "ana,e#

    E. Congenital anomalies

    9. Perinatal depression

    ?. Meconium aspiration

    A. Pulmonary hemorrhage

    >. Persistent pulmonary hypertension

    B. &ypothermia

    :. &ypoglycemia

    7. &ypocalcaemia

    . cute tubular necrosis*renal insufficiency

    E8. Polycythemia

    EE. "hrombocytopenia

    E9.;eutropenia

    ). S-e)i'i) Manae"ent )onsi#eration

    i. Fee#in= '% infants in general re#uire more calories per kg than % infants

    for Lcatch

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    35

    ii. 'erum calcium levels may be significantly depressed in preterm '% infants

    and*or those who have e+perienced hypoperfusion.

    iii. "he serum sodium concentration may also be low.

    Lon ter" -ro!(e"s o' SGA in'ants>8,>9,>?,>A

    It is difficult to determine specific effects of I%R because there are often

    overlapping effects from prematurity and asphy+ia, and also because of the

    multifactorial etiologies involved. "hese infants are at risk for poor postnatal

    growth and neurologic and developmental handicaps. "hese handicaps occur even

    in the absence of specific fetal disease 3e.g. chromosomal abnormalities4. "his is

    especially true in those who suffered perinatal asphy+ia or hypoglycemia 3orboth4

    at birth. 0or any weight group the total percentage of infants who either die before

    one year of age or are handicapped at one year is similar for '% and %

    infants. &owever, '% infants have less risk of neonatal death compared with

    preterm % infants of same birth weight but a greater risk of morbidity at one

    year of age.

    0inally, some adults who were '% at birth appear to have a higher risk of

    coronary heart disease and related health problems, including hypertension,

    non

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    36

    9. "he health of mother and fetus should be assessed throughout pregnancy by

    ultrasound and non8

    ?. /arly delivery should be considered if fetal growth ispoor.

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    37

    LARGEFORGESTATIONAL AGE INFANTS

    De'inition

    "he newbornHs birth weight is two standard deviations above the mean or

    above the ninetiethpercentile.

    Aetio(o,y

    E. Constitutionally large infants 3infants of largeparents4

    9. Infants of diabetic mothers 3e.g. classes , ) and C4

    ?. 'ome post term infants

    A. )eckwith2iedemann and other syndromes Marshall

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    38

    POSTMATURITY>8

    De'inition

    "he newbornHs gestational age e+ceeds A9 weeks.

    Aetio(o,y

    "he cause of prolonged pregnancy is unknown in most cases. "he

    following are known associations.

    E. Anen)e-$a(y! n intact fetal pituitary adrenal a+is is involved in the initiation

    of labour. Disruption in this a+is causespostmaturity.

    9. "risomies EB and E7

    ?. 'eckel syndrome 3bird< headed dwarfism4

    A. /rroneous estimation of gestational age.

    SYNDROME OF POSTMATURITY

    Postmature infants usually have normal length and head circumference. If

    they have postmaturity syndrome, however, they would have begun to lose weight.

    '% infants also may have these signs and symptoms and postmature infants may

    also be '%.

    Postmature infants are classified clinically as follows.

    E. 'tage E

    a. Dry, cracked, peeling, loose and wrinkled skin.

    b. Malnourished appearance

    c. Decreased subcutaneous tissue

    d. 6pen eyed and alertbaby.

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    9. 'tage 9

    a. ll features of stage E

    b. Meconium staining of amniotic fluid

    c. Perinatal depression 3in some cases4

    ?. 'tage ?

    a. "he findings in stage E and 9

    b. Meconium staining of cord and nails

    c. higher risk of fetal, intrapartum or neonatal death

    RIS*

    "here is an increase in mortality with postmaturity. It was shown that

    careful induction of delivery or caesarean section after A9 weeks resulted in a

    decreased mortality compared with the results seen following conservative

    e+pectant therapy.

    MANAGEMENT

    E. Prepartum management

    a. Careful estimation of true gestational age, including date from

    ultrasonic e+amination.

    b. Careful monitoring of fetal wellbeing.

    9. Intrapartum management involves use of fetal monitoring and preparation for

    possible perinatal depression and meconium aspiration.

    ?. Postpartum management

    a. /valuations for complications related to postmaturity the following

    conditions occur more fre#uently in postmature infants.

    i. Congenital anomalies

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    ii. Perinatal depression

    iii. Meconium aspiration

    iv. Persistent pulmonary hypertension

    v. &ypoglycemia

    vi. &ypocalcemia

    vii. Polycythemia

    b. /arly feeding for proper nutritional support is important.

    s both I%R babies and preterm babies are very delicate and re#uire

    speciali=ed care starting from day one of life to prevent all the above said

    complications it becomes very important to identify low birth weight babies and

    preterm babies at the earliest. )ut as statistics show most of the neonatal mortality

    occurs in rural setting i.e. ?>.> per E888 live births compared to the >.: per E888

    live births in urban settings. 2hen no medical care facilities are available neonatal

    mortality is >?.B per E888 live births compared to 99.9 per E888 live births in a

    place where all three levels of neonatal care are available. ;eonatal mortality is

    EE8 per live births in low birth weights compared to ?8 per E888 live births in

    average si=ed babies.?

    "hese statistics tell neonatal mortality is A times greater in

    very small babies compared to average babies, and B times more in rural setting

    compared to urban setting and 9.> times more in a place where no medical care

    facilities are available compared to a setup with all three levels of health care

    available.

    2here ade#uate surveillance and treatment are not possible locally, or the

    response to treatment is unsatisfactory, infants should be referred to an appropriate

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    41

    health care establishment. 'urveillance and referral are even more important for

    very

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    GESTATIONAL AGE ESTIMATION AT BIRTH

    OBSTETRIC INFORMATION>8

    "he review of following obstetric data helps in gestational age assessment

    atbirth.

    . "he clinical estimate of gestational age is usually made through careful history

    of the -MP. "he gestational age is calculated from the first day of the -MP.

    "his, accompanied by physical e+amination forms the baseline criteria for

    estimating gestational age. &owever, the maternal recall of the first day of the

    -MP is fraught with error.>>

    n additional ob$ective assessment then becomes

    necessary.

    ). ltrasonic estimation of gestational age.>B

    %estational age assessment is done

    by the retrospective study of antenatal ultrasound e+amination. /arly second

    trimester ultrasound e+amination is considered the gold standardH in the

    estimation of gestational age. "he accuracy with which gestational age canbe

    estimated by biparietal diameter 3)PD4 decreases with increasing gestational

    age. "he length of the calcified fetal femur is often measured and used in

    validating )PD measurements or used alone in circumstances where )PD

    cannot be measured 3e.g. deeply engaged fetal head4 or is inaccurate 3e.g.

    hydrocephalus4.

    C. Date of first recorded fetal activity L#uickening is first felt at appro+imately

    EB

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    NE:BORN INFORMATION

    Ne Ba((ar# S)ore

    "he tone, posture and physical appearance of the baby are considered to

    make a composite score. "his composite score is used to assess the newbornHs

    likely gestational age in the period immediately after birth. 30igure 94

    Fire 5= Ne!orn "atrity ratin an# )(assi'i)ation Ne Ba((ar# S)ore

    'ource! )allard et al., ;ew )allard 'core, e+panded to include e+tremely premature infants. K PediatrEEEE!AE:

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    44

    CLASSIFICATION OF INFANTS BY

    GESTATIONAL AGE AND BIRTH :EIGHT

    I. Infant classification by gestational age 3independent of birth weight, 2&6

    E>84

    Pre88 g

    less than that of merican newborn of same gestational age. It was assessed by

    Indian workers that 9888 g or less should be taken as the criterion of -)2 of

    Indian infants.>:

    5ery low birth weight. 35-)24! FE>88 g

    /+tremely low birth weight ! FE888 g

    Impossibly or incredibly low birth weight ! F :>8 g

    III. Classification of infants depending on both gestational age and birth weight

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    0or each gestational age, a newborn can be appropriate for gestational age

    3%4, small for gestational age 3'%4 or large for gestational age 3-%4.

    5arious criteria 3i.e. cut

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    CHEST CIRCUMFERENCE

    It is measured at the level of nipple * at the level of fourth costosternal

    $oint.9,E>

    "here is less chance of systematic or random error in estimation of chest

    circumference for the following reasons.

    E. "he level at which it is measured is based on bony land marks.

    9. It has got larger cross section compared to other anthropometric measurements

    such as mid arm circumference.

    MID1ARM CIRCUMFERENCE>:,>7,>

    "o identify the position of the mid

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    PROPORTIONALITY INDICES

    "he most commonly used inde+ of neonatal body proportionality relates

    birth weight to length.

    RohrerHs Ponderal inde+ is e#ual to one hundred times the birth weight 3in

    grams4 divided by the cube of birth length 3cm?4.

    )irth weight 3in g4

    RohrerHs Ponderal Inde+ G + E88)irth length 3in cm4

    ?

    6ther proportionality indices that relate head circumference to length

    3&C*length4 or chest circumference to length 3CC*length4 for e+ample have been

    studied occasionally but further research would be needed to show that they offer

    any advantage over the indicators previously mentioned.B

    OTHER MEASUREMENTS

    'kin fold thickness It has been used to assess newborn adiposity. 'ince

    measurement of skin fold thickness is relatively imprecise, it is not currently

    recommended for purposes of routine assessment.B

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    METHODOLOGY

    MATERIALS

    A Sor)e o' Data

    "he study sample of 788 live newborns were selected by simple random

    sampling techni#ue born at Cheluvamba &ospital attached to Mysore Medical

    College and Research Institute, Mysore from December 988: to ;ovember 9887

    3one year4.

    In)(sion Criteria

    -ive newborns of different gestational ages within :9 hours of birth.

    E. Pre

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    METHOD OF COLLECTION OF DATA

    Data was collected using standard proforma meeting the ob$ectives of the

    study.

    a Gestationa( ae assess"ent was done using modified )allardHs score

    3nne+ure 3i44.

    ! Foot (ent$ was measured using sliding calipers which is having an accuracy

    of a millimeter. 0oot length was measured from posterior most prominence of foot

    to the tip of the longest toe of the right foot. t the time of measuring ventral

    surface of foot was straightened out using gentle pressure. "he length of foot was

    documented in centimeters.

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    Fire @= S(i#in )a(i-ers se# 'or "easrin 'oot (en,t$

    Fire = De"onstration o' "easre"ent o' 'oot (ent$ sin s(i#in )a(i-er

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    # Cron $ee( (ent$ was measured using infantometer. n assistantHs help was

    sought to do the length measurement. )abyHs lower limbs were straightened out

    before doing the measurement. Measurement was documented in centimeters.

    Fire = De"onstration o' "easre"ent o' )ron $ee( (ent$ sin,

    in'anto"eter

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    e :ei$t o' t$e !a!y was measured using electronic weighing scale. "he scale

    offered an accuracy of > gms. ll the dress of baby was removed before

    weighing.

    Fire 3= Birt$ ei$t "easre# sin e(e)troni) ei$in s)a(e

    )abies were grouped into preterm, term and post

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    number of babies in this group were very less to be statistically significant. "here

    were no babies in preterm -% group.

    "he correlation between foot length and other parameters such as

    gestational age, birth weight, head circumference and crown heel length was

    analy=ed by applying correlation and regression analysis. Correlation coefficient

    3r4 values and R s#uare 3r94 values were derived for the seven groups of babies

    who have undergone analysis. 'catter diagram was plotted to demonstrate the

    correlation between foot length and other anthropometric parameters.

    Regression e#uation was derived to predict gestational age from foot length

    in various groups ofbabies.

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    RESULTS

    Ta!(e @= Se #istri!tion o' !a!ies !ase# on t$eir !irt$ ei,$t

    Birt$ei,$t

    +,

    Ma(e Fe"a(e Tota(

    N"!er N"!er N"!er

    F 9.> E8B E?.? : E9.E 98? 9>.A

    9.>

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    Ta!(e = Des)ri-ti&e statisti)s o' !irt$ ei$t n#er #i''erent )ate,ories

    Birt$

    ei,$t

    +,

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer!on#

    U--er!on#

    F 9.> 98? 8.:

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    2.8221

    1.9696

    Meanofbirthweight

    Fire >= Mean !irt$ ei$t it$ res-e)t to !irt$ ei$t ,ro-s

    3.65194

    3.5

    3

    2.5

    2

    1.5

    1

    0.5

    0

    3.5

    Birth weight

    "he figure shows the mean of birth weight with relation to birth weight

    groups.

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    Fire 64= C(assi'i)ation o' ne!orns a))or#in to t$eir "atrity

    729!"

    12415.5!"

    60475.5!"

    #er$ %re-ter$ %o&t-ter$

    Pie chart showing the classification of newborns according to their

    maturity.

    Fire 66= C(assi'i)ation o' ne!orns a))or#in to ei$t1'or1estationa( a,e

    35?

    [email protected]

    64565.?

    AGA

    SGA

    LGA

    Pie chart showing the classification of newborns according to weight

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    Ta!(e 2= Distri!tion o' !a!ies a))or#in to t$eir "atrity an# ei,$t1'or1

    estationa( a,e

    Matrity

    AGA SGA LGA Tota(

    No. No. No. No.

    "erm >8 B?.B :9 .8 9? 9. B8A :>.>

    Pre term EE8 E?.: EA E.7 8 8 E9A E>.>

    Post term >? B.B EB 9.8 ? 8.A :9 .8

    "otal B:9 7?. E89 E9.7 9B ?.? 788 E88

    6f the total 788 newborns, "erm %, "erm '% and "erm -% were

    >8 3B?.B@4, :9 3.8@4 and 9? 39.@4 respectively.

    Preterm % and preterm '% were EE8 3E?.:@4 and EA 3E.7@4,

    respectively.

    Post

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    '($berofnewborn&

    Fire 65= Distri!tion o' !a!ies a))or#in to t$eir "atrity an# ei,$t1'or1

    estationa( a,e

    550 509

    500

    450

    400

    350

    300

    250

    200

    150

    100

    50

    0

    110

    53

    72

    14 1623

    0 3

    )*) +*) ,*)

    eight-for-ge&tationa age

    #er$

    %re ter$

    %o&t ter$

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    Ta!(e = Des)ri-ti&e statisti)s o' 'oot (ent$ 'or #i''erent ro-s o' !a!ies

    Matrity

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer!on#

    U--er!on#

    Preterm

    '% EA A.::E 8.:88 >.:A:7 B.>BB>

    Preterm

    % EE8 A.>BA9 B.>7: B.78?8

    "erm

    '% :9 >.AB :.E>::

    "erm

    % >8 B.::8? 8.??:? :.>AE8 :.>:

    "erm

    -% 9? :.?? 7.99A?

    Post:E cms, respectively. "he mean

    foot length for term %, '% and -% was :.>:8?, :.8AE: and 7.8?E cms,

    respectively. "he mean foot length for post

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    Preter" Preter" Ter" Ter" Ter" Post1 Post1 Post1

    SGA AGA SGA AGA LGA ter" ter" ter"

    SGA AGA LGA

    Mean'oot(en,t$C)"E

    Fire 6@= Mean 'oot (ent$ in #i''erent ro-s o' !a!ies

    >

    ?

    3 .6236

    2

    @

    5

    6

    4

    .>3.463

    3.234@?.4@>6

    3.2???.463

    ?.53

    Matrity Gro-s

    "his figure shows the mean foot length for various groups of neonates.

    0igure shows that mean foot length increases as the gestational age increases.

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    Ta!(e 3= Des)ri-ti&e statisti)s o' estationa( ae 'or #i''erent ro-s o' !a!ies

    Matrity

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer

    !on#

    U--er

    !on#

    Preterm

    '% EA 97.:9?

    Preterm

    % EE8 9B> 9.?>:? ??.:888 ?A.>8

    "erm

    '% :9 ?B

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    Preter" Preter" Ter" Ter" Ter" Post1 Post1 Post1

    SGA AGA SGA AGA LGA ter" ter" ter"

    SGA AGA LGA

    MeanGestationa(a,eCD+sE

    Fire 6= Mean estationa( ae o' #i''erent ro-s o' !a!ies

    2

    4 @[email protected]

    @2

    @4

    52

    54

    62

    64

    2

    4

    @?.3@?.>6>

    @>.5635 5 5

    Matrity Gro-s

    "his figure shows the relation between mean gestational age and various

    groups ofbabies.

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    Ta!(e ?= Des)ri-ti&e statisti)s o' !irt$ ei$t 'or #i''erent ro-s o' !a!ies

    Matrity

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer

    !on#

    U--er

    !on#

    Preterm

    '% EA 8.:

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    Preter" Preter" Ter" Ter" Ter" Post1 Post1 Post1

    SGA AGA SGA AGA LGA ter" ter" ter"SGA AGA LGA

    Mean!irt$Dei,$tC+,E

    Fire 62= Mean o' !irt$ ei$t in #i''erent ro-s o' !a!ies

    .2@.?3

    @.2

    @

    5.4665.65>>

    5.?5?

    5.2@6

    @.55@

    5

    6.2

    6

    4.2

    4

    6.@>@

    Matrity

    Gro-s

    "his figure shows the relation between the mean of birth weight for

    different groups of babies. Post

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    Ta!(e >= Des)ri-ti&e statisti)s o' $ea# )ir)"'eren)e 'or #i''erent ro-s o'

    !a!ies

    Matrity

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer!on#

    U--er!on#

    Preterm

    '% EA 9E.>

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    Ta!(e 64= Des)ri-ti&e statisti)s o' )ron $ee( (ent$ 'or #i''erent ro-s o'

    !a!ies

    Matrity

    N"!er

    o'

    s!%e)ts

    Ran,e MeanStan#ar#

    De&iation

    >2 )on'i#en)e

    inter&a( 'or "ean

    Loer

    !on#

    U--er

    !on#

    Preterm

    '% EA ?A8 A8E A:.EE>? E.::A AB.A?E A:.97:>

    "erm

    -% 9? A>9 A7.>9E: 9.E9? A:.>:?: A.AB7

    Post

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    Ta!(e 66= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or -reter"

    AGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age

    3weeks4 EE8 8.7E8 8.B>B 8.888

    )irth weight

    3kg4 EE8 8.:B> 8.>7B 8.888

    &ead circumference

    3cms4 EE8 8.:9E 8.>E 8.888

    Crown heel length

    3cms4 EE8 8.:98 8.>E 8.888

    0rom this table, it could be observed that the foot length correlated

    significantly 3p F 8.8>4 with gestational age, birth weight, head circumference and

    crown heel length. Correlation coefficient 3r

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    /ea01ir1($feren1e1$"

    *e&tationa.agew2&"

    3rownhee..ength1$"

    Birthweight2g

    "

    Fire 6= S)atter #iara" o' t$e -reter" AGA ,ro-

    45

    40

    35

    30 *)

    25

    20

    4 6 8

    oot ength$"

    3.5

    3

    2.5

    2

    1.5

    1

    0.5

    0

    4 6 8

    oot ength$"

    B wt

    3836

    34

    32

    30

    28/

    26

    24

    22

    20

    4 6 8

    oot ength$"

    50

    45

    40

    35

    30

    4 6 8

    oot ength$"

    /,

    "his scatter diagram of the preterm % group shows correlation of foot

    length and other parameters like gestational age, birth weight, head circumference

    and crown heel length. It is evident from the figure that the foot length correlated

    significantly with all the variables. Ma+imum correlation was with gestational age

    3r G 8.7E84.

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    Ta!(e 65= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or -reter"

    SGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age

    3weeks4 EA 8.:A7 8.>> 8.889

    )irth weight

    3kg4 EA 8.7E> 8.BB> 8.888

    &ead circumference

    3cms4 EA 8.:: 8.B?B 8.88E

    Crown heel length

    3cms4 EA 8.:7B 8.BE7 8.88E

    "he foot length correlated significantly 3p F 8.8>4 with all the other

    anthropometric variables. Correlation coefficient 3r4 which indicates strong positive association between them.

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    /ea01ir1($feren1e1$"

    *e&tationa.agew2&"

    Birthweight2g"

    3rownhee..ength1$"

    Fire 63= S)atter #iara" o' t$e -reter" SGA ,ro-

    39

    37

    3533

    31 *)

    29

    27

    25

    4 6 8

    oot ength$"

    2.5

    2

    1.5

    1

    0.5

    0

    4 6

    oot ength$"

    Bt

    34

    32

    30

    28

    26/

    24

    22

    20

    4 4.5 5 5.5 6 6.5 7 7.5

    oot ength$"

    4846

    44

    42

    40

    38

    36

    34

    32

    30

    4 6

    oot ength$"

    /,

    "his scatter diagram of the preterm '% group shows correlation of foot

    length and other parameters. "his figure shows significant correlation of foot

    length with all the four parameters, ma+imum being with birth weight 3r G 8.7E>4.

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    Ta!(e 6@= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or ter" AGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age3weeks4

    >8 8.AA8 8.EA 8.888

    )irth weight

    3kg4 >8 8.A> 8.9A> 8.888

    &ead circumference

    3cms4 >8 8.?>E 8.E9? 8.888

    Crown heel length

    3cms4 >8 8.A>9 8.98> 8.888

    0rom this table, it could be observed that the correlation of foot length with

    other anthropometric variables was significant 3p F 8.8>4. Correlation coefficient

    3r

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    /ea01ir1($feren1e1$"

    *e&tationa.age

    w2&"

    3rownhee..ength1$"

    Birthweight2

    g"

    Fire 6?= S)atter #iara" o' t$e ter" AGA ,ro-

    43

    42

    41

    40

    39

    38 *)

    37

    36

    35

    6.5 7 7.5 8 8.5 9

    oot ength$"

    4

    3.5

    3

    2.5

    2

    1.5

    6.5 7 7.5 8 8.5 9

    oot ength$"

    B wt

    37

    35

    33

    31

    /29

    27

    25

    6.5 7 7.5 8 8.5 9

    oot ength$"

    5553

    51

    49

    47

    45

    43

    41

    39

    37

    35

    6.5 7.5 8.5

    oot ength$"

    /,

    "his scatter diagram shows correlation of foot length and other variables in

    term % group. 0oot length correlated significantly with all the variables,

    ma+imum being with birth weight 3r G 8.A>4.

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    Ta!(e 6= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or ter" SGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age3weeks4

    :9 8.A7E 8.9?9 8.888

    )irth weight

    3kg4 :9 8.B:> 8.A>B 8.888

    &ead circumference

    3cms4 :9 8.>A? 8.9> 8.888

    Crown heel length

    3cms4 :9 8.B?B 8.A8A 8.888

    "he foot length correlated significantly 3p F 8.8>4 with gestational age,

    birth weight, head circumference and crown heel length. ll the parameters

    showed positive correlation coefficient 3r4.

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    hea01ir1($feren1e1$"

    *e&tationa.age

    w2&"

    3rownhee..ength1$"

    Birthweight2

    g"

    Fire 6>= S)atter #iara" o' t$e ter" SGA ,ro-

    40.5

    40

    39.5

    3938.5

    38

    37.5

    37

    36.5

    36

    35.5

    *)

    5 5.5 6 6.5 7 7.5 8 8.5

    oot ength$"

    4

    3.5

    3

    2.5

    2

    1.5

    1

    0.5

    0

    5 7

    oot ength$"

    Bt

    36

    34

    32

    30

    28

    26 /

    24

    22

    20

    5 5.5 6 6.5 7 7.5 8 8.5

    oot ength$"

    5048

    46

    44

    42

    40

    38

    36

    34

    32

    30

    5 7

    oot ength$"

    /,

    "his scatter diagram shows correlation of foot length and other parameters

    like gestational age, birth weight, head circumference and crown heel length in

    term '% group of babies. It can be observed that foot length correlated

    significantly with all the parameters. Ma+imum correlation was with birth weight

    3r G 8.B:>4.

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    Ta!(e 62= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or ter" LGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age3weeks4

    9? 8.977 8.87? 8.E7?

    )irth weight

    3kg4 9? 8.8A 8.889 8.79B

    &ead circumference

    3cms4 9? 8.9EA 8.8AB 8.?97

    Crown heel length

    3cms4 9? 8.EA9 8.898 8.>E7

    "here was no correlation between foot length and any of theparameters.

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    /ea01ir1($feren1e1$"

    *e&tationa.age

    w2&"

    Birth-eight2g"

    3rownhee..ength1$"

    Fire 54= S)atter #iara" o' t$e ter" LGA ,ro-

    40.5

    40

    39.5

    39

    38.5

    38

    37.5

    *)

    7 7.5 8 8.5 9

    oot ength$"

    4.6

    4.4

    4.2

    4

    3.8

    3.6

    3.4

    3.2

    3

    7 7.5 8 8.5 9

    oot ength$"

    B wt

    36

    35.5

    35

    34.5

    34

    33.5

    33

    32.5

    32

    31.5

    /

    7 7.5 8 8.5 9

    oot ength$"

    5352

    51

    50

    49

    48

    47

    46

    45

    44

    7 7.5 8 8.5 9

    oot ength$"

    /,

    "his scatter diagram of term -% group shows correlation of foot length

    and other parameters like gestational age, birth weight, head circumfernece and

    crown heel length. "he figure shows no correlation between foot length and any of

    theparameters.

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    Ta!(e 6= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or -ost1ter"

    AGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age

    3weeks4 >? 8.8?: 8.88E 8.:9

    )irth weight

    3kg4 >? 8.A9A 8.E78 8.889

    &ead circumference

    3cms4 >? 8.9:> 8.8:> 8.8A:

    Crown heel length

    3cms4 >? 8.EAB 8.89E 8.9:

    "he foot length correlated significantly 3p F 8.8>4 with birth weight and

    head circumference. "here was no correlation of foot length with gestational age

    and crown heel length. Correlation coefficient was more with birth weight

    3r G 8.A9A4 among post

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    Ta!(e 63= Corre(ation !eteen 'oot (ent$ an# ot$er &aria!(es 'or -ost1ter"

    SGA

    Ant$ro-o"etri)

    &aria!(es

    N"!er o'

    s!%e)ts

    Corre(ation

    r

    R1sare

    r5

    -1&a(e

    %estational age

    3weeks4 EB 8.?A 8.E>> 8.E?E

    )irth weight

    3kg4 EB 8.B7> 8.A:8 8.88?

    &ead circumference

    3cms4 EB 8.E?8 8.8E: 8.B?9

    Crown heel length

    3cms4 EB 8.9BE 8.8B7 8.?97

    0rom this table, it could be observed that foot length correlated 3p F 8.8>4

    only with birth weight 3r G 8.B7>4. "here was no correlation between foot length

    and other variables.

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    Ta!(e 6?= Reression eation o' estationa( ae on 'oot (en,t$

    Matrity De-en#ent &aria!(e Reression eation

    Preterm % 0oot length %GEE.A::BN?.?7>E 0-

    Preterm '% 0oot length %GE.7B?BN9.?B>> 0-

    "erm % 0oot length % G 97.89ANE.?9?9 0-

    "erm '% 0oot length %G?E.:>?EN8.7E7 0-

    "erm -% 0oot length %G??.79EN8.B:8? 0-

    PostN8.?9B 0-

    Post

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    DISCUSSION

    "he early identification of low birth weight babies is an important pre

    where E888

    newborns were studied, showed a birth weight range of 8.7>@ term babies. (ulkarni et al.?>

    study

    showed E:.>@ preterm and 79.A@ term neonates. Kames et al.?E

    study showed

    :B.A@ term and ?.B@ preterm neonates. 'hambhu 'haran 'hah et al.A>

    study

    showed 9.@ term, B.:@ preterm and 8.A@ post

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    study which showed E?.9@ small for gestational age, 7A.7@ appropriate for

    gestational age and 9.E@ large for gestational agebabies.

    "erm %, '% and -% in present study were B?.B@, @ and 9.@,

    respectively. Preterm % and '% were E?.:@ and E.7@, respectively.

    Post@ and 9@, respectively, preterm % and '% babies were B@ and 8.:@,

    respectively and post.A:8? cm and 7.8?E cm for term '%, %

    and -%, respectively. "he foot length for post

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    % which is similar to present study. Kames et al.?E

    study showed mean

    head circumference for term % and term '% as ?A.8? 9.77 cm and

    ?9.B E.?9 cm, respectively which is comparable to present study.

    "he crown heel length of the preterm neonates in the present study ranged

    from ?9 cm to A cm with a mean crown heel length of A8.9E cm and A9.7 cm for

    preterm '% and preterm % respectively. "his is comparable to %ohil KR

    et al.?9

    study which showed a mean crown heel length of A9.: 9.87 cm for

    preterm babies. "he crown heel length of term neonates ranged from ?7 cm to

    >9 cm with a mean of AA.7 cm, A:.E cm and A7.> cm for term '%, term %

    and term -%, respectively. "his is comparable to %ohil KR et al.?9

    study which

    showed mean crown heel length of term '% as AB.9E E.9? cm and of term

    % as A7.?B ?.E? cm. Kames et al.?E

    study also showed similar results with

    mean crown heel length in term % neonates as >E.87 9.8> cm and in term

    '% neonates as AB.>7

    E.BE cm.

    "he present study was done to assess the correlation of foot length with

    gestational age. lso, other body parameters like birth weight, head circumference

    and crown heel length were also assessed for the correlation with foot length.

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    St#iesFoot (ent$ to !irt$ ei$t )orre(ation r1&a(e

    Preter" Ter" AGA Ter" SGA

    Kames et al.?E

    3E9?babies4 8.> 8.7 8.E

    %ohil KR et al.?9

    3?>?babies4 8.9 8.> 8.B

    'hambu 'haran 'hah

    et al.A>

    3E888babies4 8.9 8.7B 8.BA

    Present study

    3788babies4

    Pre1ter" Ter" Post1ter"

    SGA AGA SGA AGA LGA SGA AGA

    8.7E> 8.:B> 8.B:> 8.A> 8.8A 8.B7> 8.A9A

    Foot (ent$ to estationa( ae )orre(ation r1&a(e

    Pre1ter" Ter" Post1ter"

    SGA AGA SGA AGA LGA SGA AGA

    8.:A7 8.7E8 8.A7E 8.AA8 8.977 8.?A 8.8?:

    St#ies

    Foot (ent$ to )ron $ee( (ent$ )orre(ation

    r1&a(e

    Preter" Ter" AGA Ter" SGA

    Kames et al.?E

    3E9?babies4 8.B 8.E 8.77

    %ohil KR et al.?9

    3?>?babies4 8.9 8.A7 8.BB

    'hambu 'haran 'hahet al.

    A>3E888babies4

    8.7 8.:E 8.B8

    Present study

    3788babies4

    Pre1ter" Ter" Post1ter"

    SGA AGA SGA AGA LGA SGA AGA

    8.:7B 8.:98 8.B?B 8.A>9 8.EA9 8.9BE 8.EAB

    St#ies

    Foot (ent$ to $ea# )ir)"'eren)e )orre(ation

    r1&a(e

    Preter" Ter" AGA Ter" SGA

    %ohil KR et al.?9

    3?>?babies4 8.7A 8.BA 8.:A

    'hambu 'haran 'hah

    et al.A>

    3E888babies4 8.7> 8.B: 8.A9

    Present study

    3788babies4

    Pre1ter" Ter" Post1ter"

    SGA AGA SGA AGA LGA SGA AGA

    8.:: 8.:9E 8.>A? 8.?>E 8.9EA 8.E?8 8.9:>

    Ta!(e 6>= Corre(ation o' 'oot (ent$ it$ !irt$ ei$t an# estationa( ae in

    &arios st#ies r1&a(e

    Ta!(e 54= Corre(ation o' 'oot (ent$ an# )ron $ee( (ent$ in &arios st#ies

    r1&a(e

    Ta!(e 56= Corre(ation o' 'oot (ent$ an# $ea# )ir)"'eren)e in &arios

    st#ies r1&a(e

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    In the present study, in pre4 with gestational age, birth weight, head circumference and

    crown heel length. Correlation coefficient 3r4, head circumference 3r G 8.:9E4 and crown heel length

    3r G 8.:984.

    In preterm '% neonates, foot length correlated significantly 3p F 8.8>4

    with all the parameters. &ighest correlation of foot length was with birth weight

    3r G 8.7E>4 followed by head circumference 3r G 8.::4, crown heel length

    3r G 8.:7B4 and gestational age 3r G 8.:A74.

    In the present study, in term % neonates, foot length correlated

    significantly 3p F 8.8>4 with all the parameters gestational age 3r G 8.AA84, birth

    weight 3r G 8.A>4, head circumference 3r G 8.?>E4 and crown heel length

    3r G 8.A>94.

    In term '% babies also, the foot length correlated significantly 3p F 8.8>4

    with other anthropometric variables. Correlation coefficient 3r4, head

    circumference 3r G 8.>A?4 and crown heel length 3r G 8.B?B4. Ma+imum correlation

    was with birth weight.

    Kames et al.

    ?E

    study showed that there was a positive linear correlation

    between foot length and other indices of body si=e 3birth weight, head

    circumference, crown rump length and crown heel length4 in light

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    between foot length and birth weight 3r G 8.>4 and foot length and crown heel

    length 3r G 8.B4 waspronounced.

    In light

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    crown heel length in preterm '%, preterm %, term '% and term %

    babies and with birth weight in post in preterm % and r G 8.7E> in preterm '%4.

    In term babies also, foot length correlated significantly 3p F 8.8>4 with

    other anthropometric variables. "he correlation of foot length to birth weight and

    crown heel length 3r

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    CONCLUSION

    'ignificant correlation was observed between foot length and gestational

    age in different groups of newborns 3preterm %, preterm '%, term % and

    term '%4. 0oot length also correlated with other parameters like birth weight,

    head circumference and crown heel length significantly.

    "he correlation 3r value4 of foot length with gestational age and other

    parameters was higher in preterm neonates 3r G 8.7E8 in preterm % and

    r G 8.:A7 in preterm '%4 than in term 3r G 8.AA8 in term % and r G 8.A7E in

    term '%4 neonates. "erm '% babies showed higher correlation 3r value4 of foot

    length with gestational age and other parameters than term % babies. "he foot

    length is an efficient screening tool in identifying low birth weightbabies.

    "he highest correlation 3r value4 of foot length was with gestational age

    in preterm % babies 3r G 8.7E84 and with birth weight in preterm '%

    babies 3r G 8.7E>4. "erm % 3r G 8.A>4 and term '% 3r G 8.B:>4 babies

    showed higher correlation of foot length with birth weight. In post

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    SUMMARY

    "his study was done to know the relationship between foot length,

    gestational age and birth weight among preterm, term and post

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    :. 6f 788 neonates studied, the mean foot length was :.A9?> cm with a standard

    deviation of 8.>:99.

    "he mean foot length of pre:8? cm and 7.8?E cm, respectively.

    "he mean foot length of post

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    E?. In term % and term '% babies, the foot length correlated significantly

    3p F 8.8>4 with all the parameters. &ighest correlation was with birth weight in

    both term % babies 3r G 8.A>4 and term '% babies 3r G 8.B:>4.

    "here was no correlation between foot length and any of the parameters in

    term -%babies.

    EA. In post

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    BIBLIOGRAPHY

    E. "hacker ;. Integrated management of neonatal and childhood illness! new

    hope for child survival. PresidentHs Page. Indian Paediatrics 988:AA!EB7394!99?

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    E8. Dubowit= -M', Dubowit= D, %oldberg C. Clinical assessment of gestational

    age in the newborn infant. "he Kournal of Paediatrics E:8::!E

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    E. (umar %P, (umar (. /stimation of gestational age from hand and foot

    length. Medicine, 'cience and the -aw E???3A4!A78.

    98. &ern 2M. Correlation of fetal age and measurements between E8 and 9B

    weeks of gestation. 6bstetrics and %ynecology E7A KanB?3E4!9B

  • 8/13/2019 Study related to paediatrics

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    9:. Daga 'R, Daga ', Dighole R5, Patil RP. nganwadi workerHs participation

    in rural newborn care. Indian Kournal of Pediatrics E?B8!B9:

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    ?7. Kohnson MP, Michaelson K/, )arr M, "readwell MC, &ume R0, Dombrowski

    MP, et al. Combining humerus and femur length for improved ultrasonographic

    identification of pregnancies at increased risk for trisomy 9E. merican Kournal

    of 6bstetrics and %ynecology E> prE:93A4!E99.

    ?. Droste ', 0it=simmones K, Pascoe

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    AB. Mullany -C, Darmstadt %-, (hatry '(, -ecler# 'C, "ielsch KM. Relationship

    between the surrogate anthropometric measures, foot length and chest

    circumference and birth weight among newborns of 'arlahi, ;epal. /uropean

    Kournal of Clinical ;utrition 988:BE!A8

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    >B. 2ariyar , "in 2, &ey /. %estational assessment assessed. rchives of

    Disease in Childhood E: pp. 9EB:. Chard K. /vidence of growth retardation in neonates of apparently normal

    weight. /uropean Kournal of 6bstetrics, %ynaecology and Reproductive

    )iology E9A>3E4!>7. &ossain MM, &abib &, Dupont &-. ssociation between birth weight and

    birth arm circumference of neonates in rural /gypt. Indian Kournal of

    Paediatrics EABE!7E. 'auerborn R, 6niminga RM, (one ), 'ama R, 6epen C, /brahim %K.

    ;eonatal mid

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    ANNEKURE i

    NE: BALLARD SCORE

    'ource! )allard et al., ;ew )allard 'core, e+panded to include e+tremely

    premature infants. K Pediatr EEEE!AE:

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    ANNEKURE ii

    LUBCHENCO INTRAUTERINE GRO:TH CUR/ES

    'ource! -ubchenco -6, &ansman C and )oyd /. Intrauterine growth in length and

    head circumference as estimated from live births at gestational ages from

    9B to A9 weeks, Pedaitrics EBB?:!A8?4

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    ANNEKURE iii

    PROFORMA

    'erial ;o. !

    ;ame !

    IP ;o. of mother !

    Date of e+amination !

    ge 3in hrs4 !

    'e+ ! Male 0emale

    %estational age 3as per )allardHs score4! weeks

    Preterm*"erm*Post

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    S(.

    No.Mot$er;s Na"e In

    1-atient

    n"!er

    Gestationa(a

    ,eCDee+sE

    Foot(e

    n,t$C)"sE

    Hea#)ir)"'eren)eC)"sE

    CroDn1$ee((en,t$C)"sE

    Birt$D

    ei,$tC+,E

    A--ro-riate

    'or,estation

    S"a(('or,estationa(a,eCSGA

    E9Lar,e'or

    Pre1ter"PTE9Ter"CTE9Post1ter"PostTE

    E 'uvarna E97EA 0emale ?7 :.> ?? A7 ?.8 % "

    9 (omala E9:7 Male A8 :.B ?? A 9.B % "

    ? %eetha E9:7A Male ?7 :.> ?A A7.> 9.> % "

    A 'ahana E9:78 0emale A8 :.7 ??.? A 9.B % "

    > Ra$eswari E9B:7 Male A8 :.7 ?9.7 A.9 9.: % "

    B 'akamma E9:: Male ?7 :.B ?? A 9.> % "

    : Mangala E9:B 0emale A8 :. ?A.> A 9.:> % "

    7 'hilpa E9798 0emale ?B :.? ?? A7 9.A % P"

    -akshmi E9799 0emale A8 7.8 ?A A.> 9.:> % "E8 Man$ula E9:A Male A9 7.9 ?> >8 ?.9> % Post "

    EE 5eena E978B Male A8 :.B ?A A 9.>> % "

    E9 %owri E9:A Male ?7 :.: ??.> A7.> 9.B % "

    E? Mahalakshmi E??8 Male A8 7.9 ?A >8 ?.> % "

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    ANNEKURE &

    MASTER CHART

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    109

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