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2006
Isoxazole derivativesR 0240 Synthesis of Novel Benzofuran Isoxazolines as Protein Tyrosine Phosphatase 1B
Inhibitors. — Compounds (VIIId) and (VIIIe) reveal the highest inhibitory activity against the target enzyme with IC50 values 76 and 81 µM, respectively. — (AHMAD, G.; MISHRA, P. K.; GUPTA, P.; YADAV, P. P.; TIWARI, P.; TAMRAKAR, A. K.; SRIVASTAVA, A. K.; MAURYA*, R.; Bioorg. Med. Chem. Lett. 16 (2006) 8, 2139-2143; Med. Process Chem. Div., Cent. Drug Res. Inst., Lucknow 226 001, India; Eng.) — C. Oppel
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