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VHS- Gattaca - theme of the future ?. DVD- Cracking the Code- DeCode and Iceland. - PowerPoint PPT Presentation
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DVD- Cracking the Code- DeCode and Iceland
Controversy in IcelandA. deCODE a biotechnology company may use health, genealogical, and genetic information of 270,000 residents.
B. Why did deCODE choose Iceland?Low genetic diversity in the population
Successes: ID of genes for various diseases
Problem: Privacy is in jeopardy
1866 Mendel’s work is published 1886 Advances in microscopes=chromosomes 1880’s 1890’s Mitosis/meiosis 1900 Correns confirms Mendel’s work early1900’s Sutton and Boveri-Chromosome
Theory of Inheritance Early 1900’s Mutations discoveries led to gene
mapping 1920’s-1940’s Avery, McLeod, McCarty –DNA
carries information 1952-Watson and Crick-double helix
Mendel is the starting point for Genetics (the study of heredity and variation)
1860’s used garden peas Identified patterns of inheritance His work was ignored until Correns in
1900’s confirmed his work Genes (units of inheritance)occur in pairs
and control traits
Chromosome numbers in sexual reproduction
Diploid number (2n)- 46 for humans
Homologous chromosomes – one set from Mom and one set from Dad (23 each for humans)
Haploid number (n)- 23 for humans
Sutton and Boveri –Chromosome Theory of Inheritance = genes are carried on chromosomes
Fruity Fly studies led to discoveries: Terms: Mutation (inherited change in gene)Allele (alternate forms of a gene)Phenotype (observable features of genes)
Until 1940’s proteins were thought to be the source of genetic material
Proteins are abundant in the cell and are diverse in structure and function BUT
Fruit Flies, bacteria, and viruses led to the discovery that DNA
Alphabets (Genetic Code) DNA is made of nucleotides (A,T, G, C) RNA is made of nucleotides (A, U, G, C) Watson and Crick-double helix with
complimentary relationships A-T(U) G-C Transcription- DNA to RNA
Central Dogma of Genetics
Translation- RNA to protein