Drugs effecting the digestive organs
function
Part 1
Among substances that influence on functioning of digestive organs there are
following groups of drugs:Drugs which influence on appetite;
Emetic and antiemetic drugs;
Drugs which are used in case of disturbed function of gastric glands;
Drugs effecting liver function;
Drugs used in case of disturbed excretory function of pancreas;
Laxative agents;
Drugs which influence on motor function of intestines
Drugs which influence on
appetite:
Drugs which improve appetite
Drugs which depress appetite
Гіркоти
Полин гіркий
Золототисячник малий
Деревій звичайний
PhepranonumForm of production - 0,025 g tablets
Mechanism of action of emetic and antiemetic drugs
Metoclopramide, reglan and cerucalFrom of production: 0,01 g tablets, ampoules with 2 ml of 0,5 % solution.
MotiliumForm of production: 0,01 g tablets
Drugs which stimulate gastric secretion:
With diagnostic aim: caffeine, histamine, gastrin.With treating aim: plantain juice, plantaglucide, natural gastric juice, pepsin, hydrochloric acid.
Drugs which depress gastric secretion:
Drugs which block choline receptros:M-cholinoblockers (nonselective cholionolyutics): atropine sulfateM1-cholinoblockers with selective action (selective cholinolytics): gastrozepinganglioblockers: pirilen, benzohexonium
Drugs which block histamine-Н2-receptors: cimetidine, renitidine, famotidine, nizatidine, rexatidineInhibitors of proton pump: omeprazole, controlokProstaglandines and their synthetic derivatives: misoprostolAntacid drugs:
System: sodium hydrocarbonateNonsystem: aluminum hydroxide, magnesium oxide, almagel, maalox, renni
Gastroprotectors:Drugs which form mechanic protection of mucous membrane of stomach: sucralfate, de-nolDrugs which increase protective function of mucous barrier and stability of mucous membrane towards action of damaging factor: carbenoxolon, misoprostol
Atropine sulfate (Atropini sulfas). Powder for preparation of 0,5 % and 1 % eye drops, 1% eye
ointment, 0,0005 g tablets, ampoules with 1 ml of 0,1 % solution.
Gastrozepin (Gastrocepinum) Forms of production: 0,025 g and 0,05 g tablets; ampoules
with 0,01 g of dry substance.
Cimetidine Form of production: 0, 2 g tablets.
Ranitidine (Ranitidin) Forms of production: 0,15 g and 0,3 g tablets and ampoules with 2 ml of
2,5 % solution.
FamotidinForms of production: 0,02 g and 0,04 g tablets.
Omeprazole Form of production – 0,02 g capsules.
Antaciddrugs
Systemantacids
Nonsystemantacids
AlmagelCombined drug which contains gel of aluminum hydroxide,
magnesium oxide and D-sorbit. Form of production: 170 ml bottles.
Antacid drugs
Maalox Combined rugs which contains gel of aluminum hydroxide,
magnesium oxide.
Sucralfate Form of production: 1 g tablets
De-nolForm of production: 0,12g tablets.
Pylobact Omeprazole + Clarythromycin + Tinidazole
Schemes of combined treatment of gastric ulcer
De-nol + amoxycillin
De-nol + metronidazole
Omeprazole + amoxycillin + clarythromycin
De-nol + clarythromycin + metronidazole
De-nol + controlok + amoxycilin + clarythromycin