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Friedel Craft’s Reaction
Melvin L. Canoy
Types• Acylation• Alkylation• Other types
AcylationAn acyl chloride is an acyl group bonded to a chlorine atom. Acyl chlorides are made by reaction of the corresponding carboxylic acids with thionyl chloride. Therefore, acyl chlorides are also called acid chlorides
AcylationIn the presence of aluminum chloride, an acyl chloride reacts with benzene (or an activated benzene derivative) to give a phenyl ketone: an acylbenzene.
Examples
Alkylation
Alkyl chloride
Examples
What happens when 2°or 3° Alkyl/Acyl
chloride will be used?
Examples
Other special types
The Gatterman–Koch Formylation:Synthesis of Benzaldehydes
Examples
Others that uses other reagents
Danke!