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The 1%. Jeremy Cohen examines what makes us unique. Are there observable genetic traits that will determine how we respond to severe illness and can we measure them?
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I S E V O L U T I O N O N O U R S I D E ?
S U R V I VA L O F T H E W E A K E S T
R I C H A R D D A W K I N S
“A chicken is simply an egg’s way of making more eggs”
S O R E N S O N E T A L N E J M 1 9 8 8
T H E I N T E R N A T I O N A L H A P M A P P R O J E C T
G W A S
T I T L E
April
May
June
July
0 35000 70000 105000 140000
129,096Mb
63,178Mb
8,215Mb
3,423Mb
C O M PA R A T I V E G E N O M E S I Z E
S C H I S T O C E R C A A M E R I C A N A S C H I S T O C E R C A G R E G A R I A
F. A C R I D I D A E
E X A M I N I N G E X P R E S S I O N
R N A E X T R A C T I O N , R E V E R S E T R A N S C R I P T I O N A N D L A B E L L I N G
E X A M I N I N G E X P R E S S I O N
H Y B R I D I S AT I O N
E X A M I N I N G E X P R E S S I O N
M E A S U R E M E N T
P E TA B Y T E
E N T I R E D N A O F T H E U N I T E D S TAT E S ( T W I C E )
2 0 0 0 Y E A R S W O R T H O F F O U R M I N U T E S O N G S
S T O R A G E C A PA C I T Y O F T H E W O R L D O F WA R C R A F T
G E N E E X P R E S S I O N P R O F I L I N G I N S E P T I C
S H O C K
• S U B S T U D Y O F A D R E N A L
• A L L A D R E N A L PAT I E N T S
W I T H I N 2 4 H O U R S
E N R O L M E N T
• B L O O D F O R D N A / R N A
E X T R A C T I O N
• M A I L E D T O U Q C C G R W I T H I N
7 2 H O U R S C O L L E C T I O N
G E N E E X P R E S S I O N P R O F I L I N G I N S E P T I C
S H O C K
• E S T I M AT E D 1 8 0 0 PAT I E N T
S A M P L E S
• 1 4 0 0 PAT I E N T D I S C O V E R Y
S A M P L E / 4 0 0 PAT I E N T
VA L I D AT I O N S A M P L E
G E N E E X P R E S S I O N P R O F I L I N G I N S E P T I C
S H O C K
• D I F F E R E N T I A L
E X P R E S S I O N L E V E L S I N
S U R V I V O R S / N O N
S U R V I V O R S
• B I O L O G I C A L
E X P L O R AT I O N C L A S S I F I E R
