Embed Size (px)
Citation preview
THE SHIFTING ART OF ANIMAL BREEDING
Sijne van der Beek and Erik Mullaart
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
CRV IS ABOUT SMART HERD MANAGEMENT
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
ACTIVE AROUND THE WORLD
CRV Xseed, South Africa
CRV Lagoa, BrazilCentral Bela Vista, Brazil
CRV USA
CRV Spain
Netherlands and Belgium
CRV Germany
CRV CZ, Czech Republic
CRV Luxembourg
CRV Ambreed, New Zealand
Liberty Genetics
CRV Avoncroft, UK
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
ANIMAL BREEDING
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
IS CHANGING RAPIDLY
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
DUE TO GENOMIC AND REPRODUCTION TECHNOLOGY
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
-100
0
100
200
300
400
ConventionalLinear (Conventional)GenomicsLinear (Genomics)
16/yr
35/yr
Genetic gain has doubled
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
CRV Delta nucleus embryo production
LeftDe Volmer
Ellmau Warsi, 137 embryos
Right:Josefien 19 P rf
98 embryos
2011 2012 2013 2014 2015 20160
100020003000400050006000700080009000
Aim for 2020:
20.000 embryo’s from same number of donor animals
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
How to achieve 20.000 in 2020
• Build new facilities (ready 2017)• Further improve young stock management• Start OPU/IVP at even younger age [but only after first natural
heat]• Individualized animal protocols• Optimize the use of FSH • Optimize OPU/IVP protocol• From “no variation in # embryo’s per donor policy” to
“exploit variation between donor’s policy”
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
Today, we sell all our embryo’s
+ Highly flexible+ Environmental factors average out+ Farmer participation in breeding program
- Limited control- Vulnerable for milk price volatility- Not easy to rapidly increase scale
We need additional methods
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
Embryo genotyping
Morulea or early Blast Biopsy with
knife Freeze embryo
Biopsy
Genotype
GS breeding value
Select desired for transfer
Flush embryo
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
Effect of call rate
0 10 20 30 40 50 60 700
10
20
30
40
50
60
70
High Call rate
Low call rate
Embryo GEBV
Calf
GEB
V
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
Pregnancy rates in vivo embryos
# Embryo’s Pregnancy rateNot Biopsied 13,000 54%
Biopsied 1,200 46%
Not working for IVP yet.Therefore testing new vitrification protocol
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
Genomic prediction of number of oocytes
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
And it works!
2 4 6 8 10 12 14 160
5
10
15
20
25
30
f(x) = 1.19007930220639 x − 0.091937829518935R² = 0.269050392394974
GEBV No Oocytes
Obs
erve
d N
o O
ocyt
es
MoCaS symposium | The shifting Art of Animal Breeding | September 2016
How to further improve animal breeding
Responsible
Skilful
And Artful
Application of Technology will do the job!
