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Medical Imaging Technologies for O l i iOcular Disease Primary
Care Screening
Jimmy [email protected]‐star.edu.sg
Institute for Infocomm Research (I2R)
March 2012
I2R Technologies on Different Image M d liti f M j O l DiModalities for Major Ocular Disease Primary Care Screening
Major Causes of Blindness
C f bli d t f t t l bli dCauses of blindness as a percentage of total blindness“Global data on visual impairment in the year 2002”World Health Organization Bulletin
Ocular Diseases Primary Care Screening
Automatic Cataracts grading from Lens imagesg g g
Automatic Cup‐to‐Disc Ratio (CDR) Calculation from fundus images for Glaucoma screening
Automatic Glaucoma subtype classification from RETCAM images
Automatic Glaucoma subtype classification from OCT imagesAutomatic Glaucoma subtype classification from OCT images
Automatic Drusen detection from fundus images for AMD assessment
Automatic Cornea Analysis from OCT images
Automatic Pathological Myopia screening from fundus images
AGLAIAArchitecture for Automatic
GLaucoma Diagnosis and Its Genetic Association Study through Medical
Image InformAtics
Glaucoma
Irreversible loss of optic nervesp
Second leading cause of blindness
5.7 million glaucoma blind (total 38 million blind in the world)
Glaucoma can be slowed if detected early
Validation
Air puff eye
N = 1,676 subjects
pressure measurement
DiagnosticMean Age: 57.7 yearsGender (M/F): 832 / 844Mean CDR: 0 40
Retinal fundus photography + AGLAIA
Diagnostic performance analysis: Receiver Mean CDR: 0.40
(range: 0.10 to 0.95)
(Glaucoma Dx: 46 subjects(2 7%))
AGLAIA Operating Characteristic (ROC) curve
(2.7%)) Full ophthalmic exam at SERI
Results
We look forward to working with you