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JIMMY LIU - Ocular Image Processing

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Page 1: JIMMY LIU - Ocular Image Processing

Medical Imaging Technologies for O l i iOcular Disease Primary 

Care Screening

Jimmy [email protected]‐star.edu.sg

Institute for Infocomm Research (I2R)

March 2012

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I2R  Technologies on Different Image M d liti f M j O l DiModalities for Major Ocular Disease Primary Care Screening

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Major Causes of Blindness

C f bli d t f t t l bli dCauses of blindness as a percentage of total blindness“Global data on visual impairment in the year 2002”World Health Organization Bulletin

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Ocular Diseases Primary Care Screening

Automatic Cataracts grading from Lens imagesg g g

Automatic Cup‐to‐Disc Ratio (CDR) Calculation from fundus images for Glaucoma screening  

Automatic Glaucoma subtype classification from RETCAM images

Automatic Glaucoma subtype classification from OCT imagesAutomatic Glaucoma subtype classification from OCT images

Automatic Drusen detection from fundus images for AMD assessment

Automatic Cornea Analysis from OCT images

Automatic Pathological Myopia screening from fundus images

Page 5: JIMMY LIU - Ocular Image Processing

AGLAIAArchitecture for Automatic 

GLaucoma Diagnosis and Its Genetic Association Study through Medical 

Image InformAtics

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Glaucoma

Irreversible loss of optic nervesp

Second leading cause of blindness 

5.7 million glaucoma blind (total 38 million blind in the world)

Glaucoma can be slowed if detected early

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Validation

Air puff eye

N = 1,676 subjects

pressure measurement

DiagnosticMean Age: 57.7 yearsGender (M/F): 832 / 844Mean CDR: 0 40

Retinal fundus photography + AGLAIA

Diagnostic performance analysis: Receiver Mean CDR: 0.40

(range: 0.10 to 0.95)

(Glaucoma Dx: 46 subjects(2 7%))

AGLAIA Operating Characteristic (ROC) curve

(2.7%)) Full ophthalmic exam at SERI

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Results

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We look forward to working with you