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Acantholytic acanthoma (Epidermolytic acanthoma)
Deba P Sarma, MD
Omaha
M 60, solitary keratotic papule, scrotum
Comment
Benign epidermal tumor with characteristic histologic picture of acantholytic hyperkeratosis:
Compact hyperkeratosis, acanthosis, papillomatosis.
Acantholysis with periperinuclear vacuolization involving all layers of the epidermis except the basal layer
Hypergranulosis with large basophilic keratohyanine granules and intracytoplasmic amorphous eosinophilic bodies.
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