Acantholytic acanthoma (Epidermolytic acanthoma)

Deba P Sarma, MD

Omaha

M 60, solitary keratotic papule, scrotum

Comment

Benign epidermal tumor with characteristic histologic picture of acantholytic hyperkeratosis:

Compact hyperkeratosis, acanthosis, papillomatosis.

Acantholysis with periperinuclear vacuolization involving all layers of the epidermis except the basal layer

Hypergranulosis with large basophilic keratohyanine granules and intracytoplasmic amorphous eosinophilic bodies.