Topic Cryptosporidium - MJF Veterinary College

Mahatma Jyotiba Fule College of Veterinary And Animal Sciences, Jaipur (Raj)

Topic – Cryptosporidium

Presented by :-Dr. Abhinav Meena

2020-2021Assistant Professor

Department of Veterinary ParasitologyCollege of Veterinary and Animal Sciences,

Chomu , Jaipur (Raj)

Genus

Cryptosporidium

Contents

General Introduction

History

Signs

General life Cycle

Pathogenesis

Epidemiology

Diagnosis & Treatment

Prevention

Genus Cryptosporidium

Cryptosporidiosis is caused by protozoan parasites of thegenus Cryptosporidium, in which there are 18 ‘valid’ species.

In livestock, C. parvum, C. andersoni, C. galli have beenreported to cause morbidity and outbreaks of disease.

Some species are host specific but some are found in morethan one species.

Tansmission by fecal oral route

Person-to-person

Person-to-animal –Waterborne-Foodborne

Forms Oocyst with 4 sporozoites

History

1993: Milwaukee, West Indies Largest known water supply outbreak

400,000 persons became ill

1997: In decorative fountains

369 cases Appeared

Most cases in children <10 years old

Fecal excretion of Cryptosporidium parvum oocysts was

determined in 625 children less than five years old who

presented at the pediatric clinic of a teaching hospital in

Rawalpindi, Pakistan.

+ Signs (--)

Infections characterized by watery diarrhea

Stools with rancid odour

Weight loss

Anorexia

Yellow to white color stools

Tenesmus

Pathogenesis

Cryptosporidium parvumPrimarily infects small

intestine.

Infections characterized by

watery Diarrhea.

Impaired intestinal

absorption.

Forms oocysts

- 4-6 µm in diameter

- killed by ozone, desiccation

Post Mortem Lesions Gross lesions

(not common)

Hyperemia of intestinal mucosa.

The mucosal folds are markedly

thickened, and there are

numerous pinpoint foci of

hyperemia.

Microscopic lesions

Mild to severe villous atrophy.

Spherical organisms in the brush border.

>Common in

calves and lambs(Some days after birth)

>Other species

– Dogs (rare)

– Cats (rare)

– Horses (rare)

Epidemiology

More common with immune deficiency diseases such

as AIDS.

Cryptosporidiosis occurs worldwide. It causes 50.8% of

the water-borne diseases attributed to parasites.

When Cryptosporidium spreads beyond the

intestine,(as in AIDS) it can reach upto lungs, middle

ear, pancreas and stomach.

Unlike other coccidians autoinfection can occur.

Diagnosis

Diagnostic tests

- Acid-fast staining

- (histologic

examination).

- Microscopic detection in

feces.

- Fecal flotation.

-presumptive diagnosis based

on age.

Treatment

No specific treatment

-Supportive care

No vaccine

Prevention & Cares

Minimizing contact with infected

individuals.

Wash hands.

Wash fruits/vegetables.

Minimize contact with young

animals especially having

age of somedays.

Thank You