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Mahatma Jyotiba Fule College of Veterinary And Animal Sciences, Jaipur (Raj)
Topic – Cryptosporidium
Presented by :-Dr. Abhinav Meena
2020-2021Assistant Professor
Department of Veterinary ParasitologyCollege of Veterinary and Animal Sciences,
Chomu , Jaipur (Raj)
Genus
Cryptosporidium
Contents
General Introduction
History
Signs
General life Cycle
Pathogenesis
Epidemiology
Diagnosis & Treatment
Prevention
Genus Cryptosporidium
Cryptosporidiosis is caused by protozoan parasites of thegenus Cryptosporidium, in which there are 18 ‘valid’ species.
In livestock, C. parvum, C. andersoni, C. galli have beenreported to cause morbidity and outbreaks of disease.
Some species are host specific but some are found in morethan one species.
Tansmission by fecal oral route
Person-to-person
Person-to-animal –Waterborne-Foodborne
Forms Oocyst with 4 sporozoites
History
1993: Milwaukee, West Indies Largest known water supply outbreak
400,000 persons became ill
1997: In decorative fountains
369 cases Appeared
Most cases in children <10 years old
Fecal excretion of Cryptosporidium parvum oocysts was
determined in 625 children less than five years old who
presented at the pediatric clinic of a teaching hospital in
Rawalpindi, Pakistan.
+ Signs (--)
Infections characterized by watery diarrhea
Stools with rancid odour
Weight loss
Anorexia
Yellow to white color stools
Tenesmus
Pathogenesis
Cryptosporidium parvumPrimarily infects small
intestine.
Infections characterized by
watery Diarrhea.
Impaired intestinal
absorption.
Forms oocysts
- 4-6 µm in diameter
- killed by ozone, desiccation
Post Mortem Lesions Gross lesions
(not common)
Hyperemia of intestinal mucosa.
The mucosal folds are markedly
thickened, and there are
numerous pinpoint foci of
hyperemia.
Microscopic lesions
Mild to severe villous atrophy.
Spherical organisms in the brush border.
>Common in
calves and lambs(Some days after birth)
>Other species
– Dogs (rare)
– Cats (rare)
– Horses (rare)
Epidemiology
More common with immune deficiency diseases such
as AIDS.
Cryptosporidiosis occurs worldwide. It causes 50.8% of
the water-borne diseases attributed to parasites.
When Cryptosporidium spreads beyond the
intestine,(as in AIDS) it can reach upto lungs, middle
ear, pancreas and stomach.
Unlike other coccidians autoinfection can occur.
Diagnosis
Diagnostic tests
- Acid-fast staining
- (histologic
examination).
- Microscopic detection in
feces.
- Fecal flotation.
-presumptive diagnosis based
on age.
Treatment
No specific treatment
-Supportive care
No vaccine
Prevention & Cares
Minimizing contact with infected
individuals.
Wash hands.
Wash fruits/vegetables.
Minimize contact with young
animals especially having
age of somedays.
Thank You
