ADVIA Centaur® CP System

ADVIA Centaur® CP SystemVirtual Training Workbook

i ADVIA Centaur CP System T03002.039 Effective Date: 02/01/21

Siemens Healthineers

ADVIA Centaur® CP System

Virtual Training

ii ADVIA Centaur CP System

©2021 Siemens Healthineers. All rights reserved.

ADVIA Centaur CP System iii

Table of Contents

1: Welcome

2: System Components

3: User Interface

4: Loading Supplies and Reagents

5: Calibration

6: Processing and Reviewing QC

7: QC Setup and QC Hands-on Activities

8: Processing Samples

9: Performing Dilutions 10: Maintenance 11: Event Log

iv ADVIA Centaur CP System

Welcome

ADVIA Centaur CP System T 03002.039 1-1

Welcome

Welcome to Training

Siemens Healthineers would like to welcome you to training on the ADVIA Centaur® CP Immunoassay

System. This course is designed to teach you the skills needed to operate and maintain the Centaur CP

System.

Training Material

This training workbook includes an agenda, learning objectives, and practical exercises.

Welcome

1-2 ADVIA Centaur CP System

ADVIA Centaur® CP System Virtual Training

Objectives To prepare the customer to operate, maintain the ADVIA Centaur CP Immunoassay System.

Course Objectives After participating in the virtual lectures and hands-on exercises, you will be able to:

• Identify system components and their functions

• Navigate the user interface.

• Load/unload supplies and reagents.

• Setup and process assay calibrations and quality control.

• Process patient samples.

• Perform daily, weekly, and monthly maintenance.

• Utilize the instrument Operator’s Guide and online help.

Welcome



Training Agenda

Day 1

• System Components

• User Interface

• Event Log

• Supplies, System Fluids and Reagents

• Hands-on Practice Exercise (Loading supplies and reagents)

• Calibration

• Hands-on Practice Exercise

LUNCH

• Quality Control

• Processing Patient Samples Part 1


• Maintenance

Day 2

• Morning Review

• Sample Processing Part 2


• Event Log/ Basic Troubleshooting

BREAK OUT SESSION/LUNCH


• Perform IM Daily and/or Weekly-Monthly Maintenance

Welcome



Course Validation Checklist The participant places a checkmark beside the competency when it is completed. When all competencies are checked, the instructor and participant sign and date below as record of completion.

Topics Competencies Completed System Components Identify System Components, compartments and their

functions

User Interface Log into the software

Locate key status, task, and function buttons

System Supplies, Fluids and Reagents

Monitor Fluids, Supplies and Reagents

Scan Master Curve Cards

Load/unload system fluids, supplies and reagents

Empty Waste

Quality Control

Schedule, order and process controls

Add/Edit QC Ranges

Access ADVIA QC program

Processing and Managing Samples

Process and monitor patient samples

Manually schedule patient samples

Schedule replicates and dilutions

Review Patient Orders

Calibration Locate and scan Calibrator Definition cards

Schedule, order and process a calibration

Review calibration data and check status

Maintenance Locate, review and update the maintenance tasks

Practice scheduled maintenance tasks

Troubleshooting Utilize the Event Log

Access Operator Diagnostics

Describe the process for doing a system reboot

Siemens Customer Document Library

Access the Siemens Customer Document Library

Welcome


Instructor:______________________________________________________________________________

Participant: _____________________________________________________________________________

Date:___________________________________________________________________________________

What was most helpful to you during this program?

How can we improve this program to make it more meaningful to you?

Welcome


Customer Course Evaluation

Name of Course: ADVIA Centaur® CP System Virtual Training Date of Course:

Name of Participant:

Rate our performance in the following areas

Exce

llent

Very

Goo

d

Good

Fair

Poor

Q1 Performance for education specialist to: Create a participative learning environment

Q2 Performance for education specialist: Available for questions

Q3 Performance for education specialist: Product knowledge

Q4 Performance for education specialist: Time management in class

Q5 Performance for education specialist: Presentation skills

Q6 Performance for: Meeting overall class objectives for this education program

Q7 Performance for: Education materials / program content / support documentation

Q8 Performance for: Hands on activities as an active way to learn

System Components

ADVIA Centaur CP System 2-1

2 System Components

System Components


System Components

Resources • ADVIA Centaur CP Operators Guide

• Online Help

• PEP Connect

Objectives Upon completion of this exercise you will be able to:

• Identify the system compartments and drawers.

• Identify the luminometer, wash station, and incubation ring.

• Identify system fluids in the fluid area.

System Components


System Components

Exercise Activity and Questions 1. Match the following components and drawers to their locations on the instrument.

a. Acid & Base Reagent Compartment

b. Cuvette Loading Bin

c. Reagent Compartment

d. Sample Compartment

e. Solid Waste Drawer

f. Tip Drawers

System Components


System Components

System Interior Identify the following components on the photos of the system interior (See next page also)

a. Luminometer

b. Waste Probe

c. Aspirate Probes

d. Reagent Probe

e. Sample Probe

f. Acid Probe

g. Wash Station

System Components


System Components


System Components

System Fluids Identify the fluids kept in the fluidics area of the instrument.

a. DI Water

b. Liquid Waste

c. Wash 1

User Interface


3 User Interface

User Interface


ADVIA Centaur® CP Immunoassay System

User Interface


• Online Help

• PEP Connect


• Log onto the ADVIA Centaur CP software.

• Locate key workspace areas.

• Access the Online Help.

User Interface


ADVIA Centaur CP Security Levels Note: All User Names and Passwords are case sensitive.

Level 1 operators can perform the following, including everything in Level 2 and Level 3:

• Add and delete ratios and off-system tests

• Change Assay display name, print name and LIS code

• Enable/disable assays

• Change patient replicates and acceptable CVs

• Edit Hold results & Anonymous options in Setup

• Edit units, conversion factor, slope and intercept for each assay

• Edit ranges

• Edit Reagent OBS and shelf stability

• Set up auto dilutions and auto reflex tests

• Add, delete, and copy test and dilution profiles

• Add, delete, and copy physicians

• Add, delete, and edit users

• Edit LIS settings

• Edit sample optimization mode

• Edit date and time format

• Backup

• Change SID length

• Edit Calibration Expired options

• Send QC to LIS or ADVIA QC

Windows Log on: (see Virtual Presentation)

______________________________

Level 1 Operator ACCP Log on: (see Virtual Presentation)

User Name: _________________________

Password: _________________________

User Interface


• Edit report format

• Select Calibrator replicate RLUs and Exclude/Include

• Assign, Accept, and Waive calibrations

• Delete QC results

• Add/delete Controls

• In Diagnostics: o Move ring

o Dark Counts

o Reagent probe dispense tests

• Add, delete, import, and export maintenance tasks

• Delete entries in Maintenance Log

Level 2 operators can perform the following, including all of Level 3:

• Turn audible alarms on/off

• Edit tube types

• Export and delete patient results

• Add comments to patient results

• Edit patient results

• Scan and manually enter Calibrator definitions and Master Curves

• Edit Usage, Frequency, Replicates in Control definition

Level 2 Operator ACCP Log on: (see Virtual Presentation)

User Name: _____________________

Password: _____________________

User Interface


Level 3 Operators and Guests can perform all of the following tasks:

• Change their own password

• Turn LIS on/off

• Download orders from LIS

• Use the search and print functions

• Rerun and release results

• Edit system time and date

• Edit STAT lane in setup

• Export QC data

• Add comments in Event Log

• Export Event log

• In Diagnostics:

o Initialize Incubation Ring

o Empty or Empty/Fill Incubation Ring

o Initialize Luminometer and waste probe

o Initialize Reagent and Sample probes

o Initialize System

o Open/close Reagent and Sample Shutter

• Maintenance tasks and enter comments

Level 3 ACCP Log on: (see Virtual Presentation)

User Name: ________________________

Password: _______________________

Guest Login: (see Virtual Presentation)

User Name: ______________________

No Password

User Interface


Exercise Activity and Questions

Login 1. Log into the Centaur CP system using your user name and password.

a) Which button is used to log on as a new operator?

_________________________________________________________________

User Interface


Access Screens 2. From the workspace locate each of the following items. Select each to view the window and then

select Close to return to the workspace.

1. Access the Results Task button.

a. Which tabs can be accessed from this window?

2. Access the Definition Task button.

a. What tabs are available here?

3. Access the Maintenance Task button.

a. What tabs can you access from this window?

Identified Button

Tip Drawer

Sample Compartment

Ancillary Reagent Compartment

Primary Reagent Compartment

Incubation Ring

Event Log

Reagent Shortage Status

Reagent Calibration Stability Status

Supplies Status

Waste Status

Maintenance Status

Temperature and Voltage

User Interface


Utilize Online Help

1. Access the Event Log window. With the Event Log window opens, select the Help button and answer the following questions:

a. What do the Event Log colors indicate?

Neutral indicates:

Yellow indicates:

Red indicates:

User Interface


Navigating Through Data

1

2

3

4

5

6

1. To top of the list

2. Move up one page at a time

3. Move up one line at a time

4. Move down one line at a time

5. Move down on page at a time

6. To bottom of the list

User Interface


Status Icons

1 2 4 5 6

1. Reagent Shortage

2. Reagent and Calibration Stability

3. Supplies

4. Waste

5. Maintenance

6. Temperatures and Voltages

3

Loading Supplies and Reagents


4 Loading Supplies and Reagents






• Online Help

• PEP Connect


• Load Acid and Base reagents.

• Load Primary and Ancillary Reagents.

• Load cuvettes and sample tips.

• Replace/refill DI Water and Wash 1.

• Empty Liquid and solid waste.




Loading Acid and Base Reagents

1. The Acid/Base reagent quantities are monitored by the system.

a. How do you know when the Acid/Base reagent quantities are low or empty?

_____________________________________________________________________________

2. Does the software monitor the stability of the acid and base reagent? _____________________________________________________________________________

3. What is the stability of the Acid and Base reagents? ______________________________________________________________________________



Replace/Refill DI Water and Wash 1

1. Examine the connections on the DI water and Wash 1 container. Practice disconnecting the tubing and sensor connections.

2. Examine the liquid levels for the DI water and Wash 1. (Refill the DI water and Wash 1 if needed.)

Empty Waste

1. Examine the connections on the Liquid Waste container. Practice disconnecting the tubing and sensor connections.

a. Are the tubing connections for the Water, Wash 1 and Waste containers the same?

2. Examine the liquid level in the liquid waste container and empty the waste container if needed.

3. Withdraw the solid waste drawer, dispose of the contents and replace the drawer.

b. What should be done to update the software?

___________________________________________________________________________

Load Tip Trays

1. Observe the LED for the Tip Drawers.

2. Ensure the LED is Neutral, then, open the Tip Drawer. Examine the position of the tip trays in the drawer and notice the location of the notch.

3. Ensure that you load the tip trays properly.

a. How do you assign the tip trays?

_______________________________________________________



Check Cuvettes

1. Examine the quantity of cuvettes in the cuvette bin. If empty, load a new bag.

a. Can cuvettes be loaded while the instrument is processing?

______________________________________________________________________________

Load Primary Reagents

1. Ensure that the system is ready to receive the pack and replace the pack.

a. How do you know the pack has been read successful?



Load Ancillary Reagents 1. Open the Reagent compartment door and remove an ancillary reagent tray.

2. Either install a new ancillary reagent pack or move an existing pack to a new position in the tray.

3. Reinstall the tray.

a. How do you verify that the pack barcode was read successfully?

___________________________________________________________________________

Performing Calibration and Reviewing Data


5 Calibration




Calibration

Resources

• ADVIA Centaur CP Operators Guide

• Online Help

• PEP Connect

Objectives

Upon completion of this exercise, you will be able to:

• Check Calibration Status

• Locate and scan a Master Curve card.

• Locate and scan a Calibrator Assigned Value card.

• Process a Calibration




Check Calibration Status

1. Access the Reagent Compartment screen and check to see if any current reagent packs need to be calibrated.

a. How can you tell from this screen that a reagent pack needs to be calibrated?

2. If available, load a reagent pack with a new lot number. Check the Reagent Compartment screen again to view its calibration status.

a. How could you determine from this screen if a lot has ever been calibrated before?

______________________________________________________________________________



Scan Master Curve Calibrator Assigned Value Cards

1. Locate the Master Curve card for the new reagent lot you will be calibrating.

2. Scan the Master Curve into the software, scanning the barcodes on the side that reads “Centaur CP”. Use the handheld barcode reader and scan each one of the barcodes until all are scanned.

If the scan window does not close automatically at the end of the scan, select Cancel and scan again.

Scan Calibrator Assigned Value Card

3. Calibrate the new lot of reagent if available. If a new lot is not available, choose one with an

expired calibration or one that will be expiring soon.

4. Select the correct calibrator for that assay.

5. Locate Calibrator Assigned Value card in the calibrator box.

6. Scan the Calibrator Assigned value card on the side that reads “Centaur CP” into the software

using the handheld scanner. and scan each one of the barcodes until all are scanned.



Scan Calibrator Assigned Value Card



Start the Calibration Run

1. Load the rack with calibrators into the sample compartment. Check to make sure that the barcodes were read.

2. Select the assay that you want to calibrate.

3. Under the Calibration side, click on “Calibrate”.

4. Initialize the calibration process.



Review Calibration Data

1. When the calibration run is complete access the Results Current Calibrations tab to see the status.

a. What should the status be if the calibration run has passed?

b. What would you do if the status was Invalid?

c. What would need to be done if the status was Verify?

2. Select the calibration you just performed and open the Details window to view the data.



Calibration Data Results

Indicates the parameter passed

Indicates the parameter failed

Calibration Evaluation Ranges • Precision of calibrator replicates

• Slope – high and low cal RLUs compared to Master Curve

• Ratio of low calibrator means RLU to high calibrator mean RLU

• Low calibrator deviation

• High calibrator deviation

Observed “Instrument” Ranges After 4 calibrations of the same calibrator and reagent lot combination, an observed instrument range is established.



Processing and Reviewing QC


6 Processing and Reviewing QC




Processing and Reviewing QC Resources


• Online Help

• Processing and Reviewing QC Online Training Course

Objectives By the end of this exercise, you will be able to:

• Describe how to define controls

• List the Steps to edit a QC Definition

• Process quality control

• View QC results



Defining a Control Definition

Quality Control definition:

• Enter and edit QC ranges using the definition task button

• 50 tests per control can be defined

• 300 controls can be defined

Steps to add a control definition:

1. Access the Definition window



2. Select Controls Tab and select “Add”

3. Enter Control Details



4. Select Assay and Enter Values

5. Click “Save”



Edit QC Definitions

• Select definition tab, then control.

• Select QC definition, then Select the details button.

• Select Assay and Edit Ranges, Select Save.

1.

2.

Select the QC you want to edit



Schedule and Process QC Samples


1. Load QC Samples.

2. Select each control ID and order the assays you would like to run. Note: Make sure reagent is available for the assay in the reagent compartment.

a. List the steps you could take if there were no control barcode labels on the tubes.

3. Start the QC run by selecting the “Start” button.



View Quality Control Data 1. Access the Quality Control Results screen.

2. Select a control you ran and view the Details screen.

a. How can you tell if the result was in or out of the expected range?



QC Setup


7 QC Setup and ADVIA QC Hands-On Activities

QC Setup



QC Setup and ADVIA QC Hands-On Activities

Resources


• Online Help

• PEP Connect

Objectives


• Add a new quality control definition

• Edit a quality control definition.

• Delete a quality control definition.

• Navigate to the ADVIA QC Review Window

QC Setup



Add a QC Definition

1. Access the QC Definition tab. View it to see if there are any currently defined controls. Obtain an Expected Value sheet i.e. Bio-Rad control Ranges or Siemens Control Ranges.

2. Define and save at least one new control. As you are going through the procedure, answer the following questions:

a. What happened in the “Control Barcode” field when you typed into the “Lot” field?

b. What happened to the “Mean and “2SD” fields when you enter the High and Low ranges?

Change a QC Definition

1. Select a control you defined and change an assay mean and 2SD values.

2. Add a new assay of your choice.

Delete a QC Definition

1. Choose a Control Definition to delete. WARNING: Do not delete a Control definition that is currently being used to collect QC data.

a. List the steps you took to delete this definition file.

QC Setup


ADVIA QC

Exercise Activity and Questions 1. Select Results.

2. Select Quality Control.

a. What button should you press to access ADVIA QC?

3. Access the Review Window.

b. Was QC out for any of the listed assays? How can you tell?

4. To view specific data for an assay, check off the assay from the table on the right.

5. Select Analyze.

QC Setup


Processing Samples


8 Processing Samples

Processing Samples



Processing Samples

Resources


• Online Help

• Processing Samples Online Training Course

Objectives

Upon completion of this exercise you should be able to perform the following tasks:

• Load samples into ADVIA Centaur CP sample racks.

• Load sample racks into the sample compartment.

• Manually create orders using the Sample Compartment screen.

• Schedule a STAT sample.

• View test orders in the Results screen.

• Start the sample run.

• Remove sample racks from the sample compartment.

Processing Samples



Load Samples

1. Load the barcoded samples into Centaur CP sample racks. Position two of the barcode labels so that they are not visible in the rack window.

a. Under what circumstances would you use more than one rack to load the samples since there are 12 slots in a rack?

______________________________________________________________________________

Load Racks

1. View the sample compartment status lights before opening the sample compartment door.

a. What do the following LED colors indicate?

Neutral (unlit): _____________________________________________________________

Steady Yellow: _____________________________________________________________

Steady Green: ______________________________________________________________

2. Open the sample compartment door and load a rack. Make sure that the blinking green light goes to neutral.

a. If it changed to blinking yellow, what would you do?

______________________________________________________________________________

Processing Samples


Schedule Patient Sample Orders

Access the Samples Compartment screen and order tests for the samples you loaded.

1. Select the sample

2. Select the assay(s) this sample needs to run.

3. Select “Close” and click on “Start” to start the run.

Processing Samples


Schedule a STAT

1. Select one sample in the rack and schedule it as a STAT.

a. What changes did you see on the screen?

Processing Samples


View the Results Screen

1. Close the Sample Compartment window and select the Results button. Select the Date column to point the arrow UP. Your new orders should be at the top of the list.

a. What is the status of the orders?

Removing Sample Racks

1. View the Status LEDs above the sample compartment.

2. When the LED is neutral (indicating it is safe to remove the rack) open the sample compartment door and remove it.

Processing Samples


Deleting Records from Database

1. Select Record and Click Delete

Processing Samples


Performing Dilutions


9 Dilutions

Performing Reruns and Dilutions




Resources


• Online Help

• PEP Connect

Objectives

By the end of this exercise you will be able to perform the following tasks:

• Schedule an Offline Manual dilution.

• Schedule a system performed dilution.

• Access the Auto Dilutions settings screen.




Scheduling a Manual (Offline) Dilution

1. Access the Sample Compartment screen. Select a sample.

2. Select Dilute

3. Enter Dilution Factor in Offline Dilution, then Close.



4. Select Test, then Close.

5. Access the Results screen and search for the sample.

a. What does Flags column show?

______________________________________________________________________________



Scheduling an Online Dilution

1. Access the Sample Compartment window, select a patient sample.

2. Select Test.

3. Select Dilute.

4. Select Test again, then select dilution factor and close.



5. Access the Results screen and search for the sample.

a. What does Flags column show?

b. What number is indicated in the Dilution Factor column?



ADVIA Centaur CP Dilutions

Manual Dilutions

1. Select Rack and Sample.

2. Select Dilute.

3. Enter dilution factor in Offline box.

4. Close Dilutions.

5. Select Test.

Auto Dilutions


2. Select Test.

3. Select Dilute.

4. Select Test.

5. Select on-board Dilution factor button.

6. Uncheck Undiluted box in the Offline area.

7. Close Dilutions.

Neat and Diluted


2. Select Test.

3. Select Dilute.

4. Select Test.

5. Select on-board Dilution factor button.

6. Leave Undiluted box checked.

7. Close Dilutions.

Manual and Auto Dilutions


2. Select Dilute.

3. Enter dilution factor in Offline box.

4. Close Dilutions.

5. Select Test.

6. Select Dilute.

7. Select Test.

8. Select on-board dilution factor.

9. Close Dilutions.



Maintenance


10 Maintenance

Maintenance



Software and Daily Maintenance

Resources


• Online Help

• PEP Connect

Objectives


• Access the Maintenance Schedule.

• Utilize Online Help to view specific maintenance procedures.

• Perform the Automated Daily Cleaning procedure.

• Perform the Aspirate Probe Bubble Detector Calibration procedure.

• Utilize the Maintenance log.

Maintenance



Maintenance Software

Accessing the Maintenance Schedule and Online Help

1. Select the Maintenance status button to open the Maintenance Schedule.

a. How else can you access the Maintenance screens?

2. View the Overdue column for any overdue indicators.

a. How can you identify that a maintemance is overdue?

3. Select the “Automated Daily Cleaning” procedure and then select “Procedures.” Online Help opens.

a. What information is available to you?

Maintenance


4. Close the Help window and select “Procedures” again. Under the “Automated Maintenance Procedure” section select “Performing an Automated Daily Cleaning.”

5. When the procedure opens, scroll down to the blue hyperlink “Preparing the Cleaning Solution Used on the System” and select it. When you finish reviewing the procedures, close the Online Help.

Performing the Automated Daily Cleaning Procedure

1. Make sure the analyzer is in the Ready state.

2. From the Maintenance Schedule, select the Automated Daily Cleaning procedure and then select “Perform.” Follow the instructions on the screen to complete the procedure.

a. What supplies needed to perform the Automated Daily Cleaning procedure?

_______________________________________________________

Performing the Aspirate Probe Bubble Detector Calibration Procedure

1. Make sure the analyzer is in the Ready state.

2. From the Maintenance Schedule, select the Aspirate Probe Bubble Detector Calibration Procedure and then select “Perform.”

Utilizing the Maintenance Log

1. After the Automated Daily Cleaning procedure is finished, select the Maintenance Log tab. Select the Date column header and point the arrow down so that the entries sort in a descending order by date. This places the cleaning task you just performed at the top.

Maintenance



Weekly Maintenance Exercise

Resources


• Online Help

• PEP Connect

Objectives

By the end of this exercise, you will be able to:

• Perform system shutdown.

• Perform system interior maintenance.

• Update the Maintenance log.

• Perform the Automated Weekly Cleaning procedure.

Maintenance


Weekly Maintenance Quick Guide

Shutdown System

1. Make sure samples are finished processing and system status is Ready.

2. Turn analyzer power switch to OFF.

Clean System Interior

1. Prepare Cleaning Solution.

a. Dilute one bottle of Concentrated Cleaning Solution to 2000 mL with DI water.

2. Open the top cover.

3. Clean incubation ring cover:

a. Move sample and reagent probe mechanisms out of the way.

b. Wipe incubation ring cover with gauze saturated with cleaning solution.

c. Rinse incubation ring cover with gauze saturated with water.

d. Dry incubation ring cover with lint-free tissue.

4. Clean exterior of reagent probe:

a. Lift reagent probe to highest point.

b. Check probe for damage.

c. Wipe downward with alcohol wipe.

d. Reposition probe over waste bowl.

5. Clean exterior of waste probe:

a. Wipe probe with alcohol wipe.

6. Clean probe rails:

a. Wipe all probe rails with alcohol wipes.

b. Allow to dry before powering on.

Update Maintenance Log:

1. Update Maintenance Log:

o Select Maintenance.

o Select System Interior.

o Select Perform.

o Enter Comment as needed.

o Select OK.

Maintenance


Perform Automated Weekly Cleaning

1. Make sure system is in the Ready state.

2. Prepare DI Water container:

o Disconnect DI Water container from the system and dispose of water.

o Pour dilute cleaning solution into DI Water container, replace cap, and rock 10 times.

o Let container sit for 10 minutes.

3. Start the automated procedure:

o Select Maintenance.

o Select Automated Weekly Cleaning.

o Select Perform.

4. When procedure 1 displays:

o Connect DI water container with cleaning solution to system.

o Select Accept.

5. When procedure 5 displays:

o Disconnect DI Water container and dispose of cleaning solution.

o Fill DI Water container with 3 liters of DI water and rock at least 5 times to rinse.

o Dispose of water and repeat rinsing at least 3 times.

o Fill DI Water container with fresh DI water and connect to system.

o Select Accept.

6. When procedure 9 displays, select OK.

Maintenance



Monthly Maintenance

Resources


• Online Help

• PEP Connect

Objectives

By the end of this exercise, you will be able to:

• Perform the Automated Monthly Cleaning procedure.

• Export Data from Historical.

Maintenance


Exporting data 1. Select Historical.

2. Select Export.

3. Select Selected Records, Today’s Records, All Records, Range or Run ID.

4. Leave File selected.

5. Leave TAB selected. This file can be viewed with Excel, NotePad, or WordPad.

6. Select File Location.

o Find the location to save the exported file – hard drive, floppy drive, USB stick, and CD.

o Type file name and file extension. The software does not automatically add the file extension to the file name. If you forget to add the extension at this point, you can always add it later on another PC.

o Select Save.

o Select OK.

You will see the progress of the save on the bottom left of the Export Results screen.

When the export is complete, the Export Results screen will close.

Troubleshooting


11 Troubleshooting

Troubleshooting



Troubleshooting

Resources

• Maintenance section in the Centaur CP Operators Guide

• Online Help

• PEP Connect

Objectives


• Access the Event Log.

• Utilize the Event Log to investigate a specific system error.

• Discuss how to troubleshoot common system errors.

Troubleshooting


Event Log 1. Select Event.

2. Select Details.

Troubleshooting



Using the Event Log

1. Open the Event Log status button

a. How can you differentiate between a warning message and an error message?

2. Select an error message in the Event Log.

a. How can you determine the possible causes of this error?

3. Select a warning message in the Event Log.

a. How can you determine the corrective actions for this message?

Troubleshooting


Troubleshooting Common System Errors

Reagent Probe TAG Calibration Failures • Verify the DI water tubing is connected properly and not kinked.

• Perform a Reagent Probe Prime in Diagnostics.

Reagent Probe Volume Check Errors

• Verify the DI water tubing is connected properly and not kinked.

• Perform a Reagent Probe Prime in Diagnostics.

• Check the placement of the reagent pack.

• Verify the reagent pack is not empty.

Troubleshooting


Reagent Probe Move Errors

• Verify the shutter is seated properly.

• Check for obstructions near the shutter and Reagent Probe wash station.

Cuvette Loading Errors

• Verify the cuvette bin is not empty.

• Move the conveyor up.

• Press Restart Cuvette Loader.

• If problem persists, turn system off and check for obstructions.

Troubleshooting


Cuvette Loading Errors

• Turn system off.

• Use a pipet to remove obstructions from the vertical chute.

• Remove the cuvette loader and clear cuvettes.

• Turn system on.

Troubleshooting


Luminometer Errors

• Check the Acid and Base stability.

• Check Acid and Base bottle placement.

• Prime Acid and Base in diagnostics.

Troubleshooting


Luminometer Errors Continued

• If the steps on the previous page do not resolve the Noise Flag and Signal Errors, check the Acid and Base tubing.

• Verify the tubing is tightened and liquid is not leaking from the fittings.

Troubleshooting


Luminometer Errors Continued

If there are signal errors, it could be static electricity. Perform a Dark Count Test with cuvettes and without cuvettes. Counts should be <500 RLU.

Troubleshooting


Wash Station Errors

• Verify the Wash 1 tubing is connected properly.

• Verify the Wash 1 container is not tilted and the tubing is not kinked.

• Make sure the Liquid Waste tubing is not kinked or compressed.

• Repeat the Aspirate Probe Bubble Detector Calibration.

Wash Station Errors Continued

• Check the Wash 1 container tubing.

• Verify the Wash 1 container is not tilted.

• Make sure the Liquid Waste tubing is not kinked or compressed.

• Perform the Aspirate Probe Bubble Detector Calibration.


Replace gray peripump tubing.

Troubleshooting



Gently move the aspirate probes up and down.

Troubleshooting


Sample Probe Integrity Errors

Corrective Actions

• Add more sample to the tube.

• Check the sample for foam or bubbles.

• Verify the Tube Type settings are correct.

Sample Probe Errors If this error occurs in the middle of a run, call Technical Support.

Troubleshooting


Documents

ADVIA Centaur® CP System