DEPARTMENT OF PAEDIATRICS...10-Year Report 5 It has been a pleasure for me to serve as Paediatrician-in-Chief of the Department of Paediatrics at Mount Sinai Hospital, part of Sinai

DEPARTMENT OF PAEDIATRICS

10-YEAR REPORT 2009-2018

2 DEPARTMENT OF PAEDIATRICS

© 2019 Department of Paediatrics, Mount Sinai Hospital

This report was compiled by Dr. Sarah Hutchinson, Ms. Cynthia Yeh, Ms Amuna Yacob, Ms. Nerizza Matignas, and Ms. Angela Lim with material provided by Dr. Shoo Lee, Dr. Edmond Kelly, Dr. Sharon Unger, Dr. Amish Jain, Dr. Emer Finan, Dr. Jennifer Young, Dr. Amish Jain, Dr. Adel Mohamed, Ms. Kasia Pytlik, Ms. Janet Narciso, Ms. Nely Amaral, Mr. Sonny Yeh, Mr. Philip Ye and Dr. Sarah Hutchinson. Layout and design were provided by Laurie Barnett.

310-Year Report

I would like to offer my gratitude and congratulations to everyone in the Department of Paediatrics for their hard work and dedication to improving patient care over the last 10 years. During Dr. Shoo Lee’s tenure, the Department has gone from being primarily a clinical department to hosting the most productive research NICU in Canada. Innovations including Family Integrated Care, the Rogers Hixon Ontario Human Milk Bank, continuous quality improvement using the Evidence-based Practice for Improving Quality (EPIQ) method, and the integration of point-of-care services like targeted neonatal echocardiography have not only improved neonatal outcomes, but are reshaping infant care across Canada.

This 10-year report highlights the extraordinary impact the Department of Paediatrics has had under the leadership of Dr. Lee. Through patient-centered care, interdisciplinary teamwork, integrated research, and a commitment to continuous quality improvement, the Department of Paediatrics has become a model of high-quality, cutting-edge care for others to follow.

Thank you for the commitment of our clinical and research teams in the Department of Paediatrics and our government and philanthropic funding partners. Your devotion has improved the lives of the thousands of fragile newborns and their families who stay at Mount Sinai Hospital each year. We are grateful for all you do and are proud of your continuous efforts to make care better.

Dr. Gary Newton, President and CEO

FOREWORD


TABLE OF CONTENTS

Foreword......................................................3

Message from the Paediatrician-in-Chief .....5

Executive Summary .....................................6

Clinical .......................................................12

Research ...................................................28

Education ...................................................34

Donors .......................................................41

People........................................................43

Awards and Honours..................................50

Funding ......................................................54

Publications ...............................................60

510-Year Report

It has been a pleasure for me to serve as Paediatrician-in-Chief of the Department of Paediatrics at Mount Sinai Hospital, part of Sinai Health System, from 2009 to 2018. During this time, the Department has transformed from a primarily clinical department into an international leader in innovative, quality neonatal care; high-caliber research; and training excellence for the leaders of the future. This remarkable transformation was made possible only through the dedication and selfless contributions of staff members in the Department. Congratulations must go to them for their hard work and success.

I am especially proud of how the individuals representing many professional disciplines in the NICU, from physicians to nurses, respiratory therapists, dieticians, pharmacists, social workers and others, have transformed themselves into a true inter-professional team and elevated care to the next level. The culture change that resulted from their teamwork focuses on patient-centered care and continuous, evidence-based quality improvement to ensure that our fragile patients have the best start in life. For example, the pioneering and adoption of the Family Integrated Care (FICare) philosophy made parents an integral part of their infants’ NICU-care team and improved infant outcomes. FICare is truly revolutionary and has the potential to fundamentally transform the delivery of health care globally.

Over the last 10 years, we were fortunate to move into new clinical and administration space, which coincided with the expansion of our service offerings. The David and Stacey Cynamon Mother & Baby Unit and Department of Paediatrics administration space opened in 2012 and a new state-of-the-art NICU was completed in 2014. The new NICU has a single-room design and is equipped with a fully electronic health information system that integrates antenatal, obstetric, neonatal and follow-up care. The opening of the Roger Hixon Ontario Human Milk Bank marked a major milestone not only for Mount Sinai Hospital, but also for our partners at the Hospital for Sick Children and Sunnybrook Hospital, and the province of Ontario. The use of point-of-care services in the NICU, including targeted neonatal echocardiography and lung ultrasound, has reduced the need to transport fragile infants and improved diagnoses and patient care.

Our achievements would not have been possible without the unwavering support and visionary leadership of the Sinai Health System Executive Team, the Board of Directors and the Sinai Health System Foundation. Acknowledgements must go to the Lunenfeld-Tanenbaum Research Institute, the University of Toronto, the Hospital for Sick Children and the Ontario Ministry of Health and Long-Term Care for their generous support and partnership. Thanks must also go to the Parent Advisory Board and many parent volunteers who spent countless hours helping families in the NICU and the NICU staff who care for them. Finally, we would like to extend a very warm expression of thanks to everyone who has contributed to our work, either as a member of our team or by providing financial assistance to the Department.

Dr. Shoo Lee, Paediatrician-in-Chief

MESSAGE FROM THE PAEDIATRICIAN-IN-CHIEF


Dr. Shoo Lee has led the

Department of Paediatrics

at Mount Sinai Hospital, part

of Sinai Health System, as

Paediatrician-in-Chief for the

last 10 years. The time has been

filled with growth, changes, and

improvements in the Department,

which are summarized in this

report. The report is divided

into three sections reflecting

the three areas of excellence

in the Department — Clinical,

Research, and Education.

EXECUTIVE SUMMARY

710-Year Report

The Department of Paediatrics is one of the largest academic neonatal programs in Canada with 112 beds and over 10,000 patient encounters each year. In addition, we are the only hospital in Canada that performs advanced procedures like laser and in-utero fetal surgery for pregnancies. Medical care is provided by 13.7 full-time equivalent neonatologists, working with a dedicated inter-professional team of nurses, respiratory therapists, physiotherapists, occupational therapists, lactation consultants, social workers, dieticians, pharmacists, administrative, and other support staff.

Research is conducted by all neonatologists in the Department and is supported by research staff from the Maternal-Infant Care Research Centre (MiCARE), which Dr. Lee established as an in-house facility to support Departmental research. Our Department also prioritizes high-quality, cutting-edge education and clinical training for medical students, specialty residents, sub-specialty fellows, nurses, and respiratory therapists, as well as post-graduate research training for both basic and clinical sciences.

Our 7 clinical services include the following:

• Antenatal consults for women with high-risk pregnancies in our Labor and Delivery Unit, Antenatal Ward, and Special Pregnancy Clinic

• Resuscitation and stabilization of infants in the Labour and Delivery Unit

• Healthy newborn care in the 55-bed David and Stacey Cynamon Mother and Baby Unit

• Both level 2 and level 3 neonatal intensive care in our mixed-acuity, 62-bed NICU

• Outpatient post-natal and postpartum care in our Postnatal Ambulatory Clinic (PNAC)

• 7-day-a-week breastfeeding support in the NICU

• Developmental follow-up for high-risk infants in our Follow-up Clinic

Department of Pediatrics in a Nutshell

=

Highlights of the last 10 years


Between 2009 and 2018 under Dr. Shoo Lee’s leadership, the Department of Paediatrics significantly improved the provision of care, expanded our research outputs, and continued to deliver world-class education and training.

Highlights of the Last 10 Years

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CLINICAL CAREProviding the best clinical care is at the heart of everything we do in the Department of Paediatrics. Over the last 10 years, improvements in the facilities, staffing, processes of care, and services were all geared towards improving the outcomes and quality of life of our most vulnerable patients. We were fortunate to have several facility upgrades that enhanced both the care environment for patients and tools available to medical professionals. Between 2012 and 2014, we moved into new spaces for the Mother and Baby Unit, Neonatal Intensive Care Unit (NICU), and Department of Paediatrics’ administration. In addition, a fully electronic NICU information system was implemented. The new NICU is a single-room design that provides space for families to stay with their infants and enabled the re-organization of the NICU into a mixed-acuity model to minimize patient movement.

During Dr. Lee’s tenure, he made changes to the Department staffing that helped increase efficiency, lower costs, and improve the quality of care. For example, he reorganized the Department and clarified job descriptions for neonatologists, recruited an additional 3.7 full-time equivalent neonatologists, and hired a nursing Clinical Coordinator, a Nurse Educator, and a dedicated Quality-Safety Nurse.

Two key changes were made to the care culture in the NICU over the past 10 years. First, the NICU implemented a continuous quality improvement process that uses the Evidence-based Practice for Improving Quality (EPIQ) method designed by Dr. Lee. Now, continuous quality improvement is ingrained in the culture of the Mount Sinai NICU and has led to multiple leading practice awards. Second, Dr. Lee and Dr. Karel O’Brien developed the Family Integrated Care model, which was implemented in the Mount Sinai NICU in 2011 as a pilot program and is now the philosophy of care for the whole NICU.

Many changes were made to the clinical services offered by the Department of Paediatrics. For example, services like Level 1 neonatal care and developmental follow-up were brought in-house for greater consistency of care. The Rogers Hixon Ontario Human Milk Bank and point-of-care technologies, including functional echocardiography and lung ultrasound, were integrated into the NICU services. Last, the Post-Natal Ambulatory Clinic (PNAC) and Life With A Preterm Baby Program were established to fill care gaps after discharge home. Together, these service changes made the Mount Sinai NICU a leader in quality NICU care.


RESEARCHOver the last 10 years, research has been a key area of focus for the Department of Paediatrics. As a result, the Department now hosts one of the most productive research NICUs in Canada. Our faculty members continually strive to be at the leading edge of perinatal-neonatal medical research. Between 2009 and 2018, Dr. Lee made many organizational changes that have significantly enhanced our research capabilities. For example, the Department started providing training and mentorship to faculty and enabling research through protected research time. In addition, the Department recruited research expertise and increased the number of clinician-scientists in the Department from 0 to 6. Finally, Dr. Lee established the Maternal-Infant Care Research Centre (MiCARE) to support Departmental research.

The research program is complemented by the major national and international networks and multi-centre trials that are coordinated and managed at Mount Sinai Hospital through MiCare. MiCare is the coordinating centre for the Canadian Neonatal Network™ (CNN), Canadian Preterm Birth Network (CPTBN), Canadian Neonatal Follow-Up Network (CNFUN), Canadian Pediatric Surgery Network (CAPSNet), Canadian Neonatal Transport Network (CNTN), International Network for Evaluating Outcomes in neonates (iNeo), and WHO Perinatal Surveillance System. Together, the networks provide benchmarking and outcomes data that contribute to both the continuous quality improvement efforts and the research productivity of the Department of Paediatrics.

The Department of Paediatrics has consistently produced a large quantity of high-quality research over the past 10 years. The Department published 731 manuscripts in peer-reviewed journals. In addition, we were awarded 160 new research operating grants valued at $103,968,934, including 41 CIHR grants; and the annual grant funding for the Department increased from $4.7M in 2009 to $16.2 M in 2018. The number of peer-review grant-funded principal investigators among Department members increased from 5 in 2009 to 10 in 2018, with 5 investigators receiving CIHR awards. Between 2009 and 2018, the Department made over 1000 national and international presentations and received 104 awards and honours for our work.

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EDUCATION The level of quality care and research in the Department could not be achieved without cutting-edge training programs. Our training programs reach a wide spectrum of healthcare professionals, both nationally and internationally.

The Department of Paediatrics is a leader in medical training. Over the past 10 years we have provided training for 528 specialty residents and 205 subspecialty fellows as well as elective training for 138 medical students, midwives, physician assistants, and others. In addition, Department members were instrumental in developing and implementing national curricula and exams for perinatal-neonatal fellows.

Research is a key area of focus for the Department of Paediatrics and requires extra training on top of a typical medial education. In addition to research training and mentorship of specialty and sub-specialty residents in pediatrics and neonatology, the Department has provided post-graduate research training for 8 researchers at the masters, doctoral or post-doctoral level, and Dr. Lee established a unique clinician-scientist training program that has successfully trained 5 clinician-scientists, with 1 more in training.

In the last 10 years, Dr. Lee has established the Department of Paediatrics at Mount Sinai Hospital as a major coordinating centre for international training programs in neonatal medicine and nursing. Researchers and clinicians come from around the world to observe and learn from us. In addition, we run two international programs in neonatal medicine and nursing.


The Department of Paediatrics plays a vital role in

the care of all infants born at Mount Sinai Hospital,

but particularly those born following high-risk

pregnancies or in need of intensive care. Close

to 7,000 infants a year are delivered in

the hospital and over 1,100 per year are

admitted to our neonatal intensive care

unit (NICU). To ensure infants born at

Mount Sinai Hospital have the best start

in life, the Department of Paediatrics provides a

breadth of services that range from perinatal care

through to early childhood.

The Department of Paediatrics continually strives to

improve patient care. To this end, the Department

has made significant changes since 2009 to

improve the quality and continuity of care provided

to our patients, with a significant focus on delivering

patient and Family Integrated Care. Throughout

this report we provide details and examples of the

changes in the Department, but key changes and

services are highlighted here:

CLINICAL

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CLINICAL SERVICES

Antenatal ConsultsAntenatal consults are an important part of the services provided by physicians in the Department of Paediatrics. They provide consults to both in-patient high-risk mothers in the Antenatal Ward and Labour and Delivery Unit and out-patient high-risk mothers in the High-Risk Pregnancy Program.

Number of Antenatal Consults

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

650 667 740 806 748 683 722 681 675 726

Delivery Room CarePhysicians, nurses, and respiratory therapists are all intimately involved in providing delivery room care for all infants who are born at Mount Sinai Hospital. Whether it is a planned high-risk delivery with an infant who needs immediate respiratory care and stabilization, an emergency situation, or the birth of a healthy baby, the Paediatrics Team is always ready to provide newborn care.

Healthy Baby Care in Mother and Baby UnitPediatricians, nurses, and respiratory therapists ensure that all infants born at Mount Sinai and staying in the 55-bed David & Stacy Cynamon Mother and Baby Unit are healthy and ready to go home before discharge.

Number of Mother and Baby Unit Discharges

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

5773 5779 5802 5571 5846 5473 6205 5621 5711 6014


Neonatal Intensive Care UnitThe Mount Sinai NICU is a 62-bed, mixed-acuity unit that provides Level 2/3 neonatal care. We admit more than 1,100 infants per year on average, and since we moved to our new NICU space in 2014, all infants have their own rooms. The NICU is focused on interdisciplinary care; neonatologists, nurses, respiratory therapists, social workers, nutritionists, lactation consultants, psychiatrists, phycologists, and other specialists all work together to provide both the infants and their families high-quality care.

Number of NICU Discharges

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

1083 1214 1212 1220 1118 1111 1161 1164 1219 1197

Postnatal Ambulatory ClinicEstablished in 2011, the Postnatal Ambulatory Clinic (PNAC) provides consistent outpatient care during the early postpartum and neonatal period to infants delivered at Mount Sinai and their mothers. The clinic is open 7 days a week and paediatricians provide screening and neonatal assessments for near-term infants less than 3 months old and preterm infants of less than 1 month corrected age. An ophthalmologist provides follow-up eye exams for retinopathy of prematurity and maternal services include breastfeeding support, maternal staple/clip removal, maternal postpartum assessment, and maternal blood work.

Number of Paediatric PNAC Visits

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

0 0 302 584 660 755 793 699 737 765

Breastfeeding SupportThe Department of Paediatrics NICU has integrated lactation consultants who provide 7-day-a-week lactation support for all mothers with infants in the NICU.

Neonatal Developmental Follow-Up ClinicSince 2010, the Neonatal Developmental Follow-Up Clinic provides screening and diagnostic services for high-risk infants. The interdisciplinary staff works together to diagnosis infants with any adverse outcomes as early as possible.

Number of Follow-Up Visits

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

0 591 1327 1298 1334 1462 1500 1496 1397 1329

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FACILITY IMPROVEMENTIn the past 10 years, the Mother and Baby Unit, Department of Paediatrics office space, and NICU moved into new, state-of-the-art spaces. In 2012, the David and Stacey Cynamon Mother and Baby Unit opened. It has more than 40 beds, decentralized care stations to enable efficient computer charting and allow clinicians to be closer to the point of care, and a clean and safe environment for patients including more sinks close to patient rooms and enhanced security. The new Department of Paediatrics administration space opened in 2013 with an efficient design that placed offices around a central administrative area and allowed more staff to work together in the same space.

In 2014, Mount Sinai Hospital opened a new 62-bed NICU with a mixed-acuity model and single-room design. In the mixed-acuity model, either Level 2 or Level 3 NICU care can be provided in any bed, which improves access to tertiary care and limits infant movement. The single-room design allows each infant to have a private room with improved noise, light, and infection control in addition to space and privacy for families. It also makes it easier for parents to participate in daily medical rounds. In addition to single rooms, the new NICU has 6 resuscitation bays, 8 negative pressure airborne isolation rooms, a new fleet of VN500 ventilators, and a procedure room. For families, there is a comfort care room, family lounge space, and improved pumping space for mothers, making it easier for families to spend time with their infants in the NICU. The big windows let light in and make the space welcoming, and several rooms even have an amazing view of the CN tower.


CHANGES IN STAFF NUMBERS AND ORGANIZATIONThe job descriptions of staff physicians were clarified, with each neonatologist assigned to distinct career tracks as academic clinicians, scientists, educators or administrators, and with clear responsibilities, expectations and performance-based reimbursement. We increased the number of staff neonatologists in the Department by 3.7 full-time equivalent, and 1.0 full-time equivalent staff pediatricians now provide coverage within the Mother and Baby Unit, which minimizes the need for external paediatricians. Also, the coverage model was changed to a weekly format from a daily format to improve continuity of care for patients in the Level I nursery. Reorganization of the Department and improvement in our revenue stream enabled us to reduce the annual departmental operating deficit while increasing and introducing new services at the same time. In addition, Mount Sinai Hospital now has the most cost-efficient NICU among the hospitals in Toronto, delivering care at the lowest cost per patient day.

Since 2009, there have been many staffing changes in the Department of Paediatrics. To the nursing team we added a Nurse Educator position, a nursing Clinical Coordinator position and a dedicated Quality-Safety Nurse. These positions were added to improve the quality and continuity of care provided in the Department. In particular, the Nurse Educator provides training for nurses and the Quality-Safety Nurse coordinates and tracks the activities of the Improving Quality Team. The respiratory therapists also made staffing changes to improve the quality of care. Now there is one NICU respiratory therapist dedicated to resuscitation and another dedicated to transport. These changes ensure fragile infants receive the consistency of care they need, even when they are transported for diagnostic procedures or surgery.

CHANGES IN SERVICES AND CARE DELIVERYAn area of focus for the Department of Paediatrics Clinical Care team over the last 10 years has been to bring more services in-house and increase access to point-of-care technology. With these goals in mind, the Neonatal Developmental Follow-Up Clinic moved in-house in 2010, the PNAC clinic was established in 2011, and the Rogers Hixon Ontario Milk Bank was established at Mount Sinai Hospital in 2013. Furthermore, the clinicians in the Department of Paediatrics have become national leaders in the development and implementation of point-of-care technology like targeted neonatal echocardiography and lung ultrasound.

Neonatal Intensive Care

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Neonatal Intensive Care

1164 average

discharges per year

33.9 weeks’ average gestation

64% 14.8

days average stay

2246 grams average

birth weight

75% singletons

21% twins

4% triplets or more

KEY METRICS

infants < 37 weeks’ gestation


FAMILY INTEGRATED CARE (FICARE)The Mount Sinai Hospital NICU is a world leader in a new care philosophy called Family Integrated Care (FICare) that was developed by Dr. Shoo Lee and Dr. Karel O’Brien. FICare is a philosophy of care that empowers parents to become a part of their infant’s care team in the NICU. When infants are admitted to the NICU they are physically separated from their parents for extended periods of time, which can affect the physical, psychological, and emotional health of both infants and their parents. The goal of FICare is to facilitate collaboration between NICU staff, Veteran Parents, and current parents to integrate families as partners in their infant’s NICU care team, which will promote parent-infant interactions and build parents’ confidence to care and advocate for their infant, both in the NICU and when discharged.

Dr. Lee and Dr. O’Brien piloted FICare at Mount Sinai Hospital in consultation with an inter-professional program steering committee from 2011 to 2012, enrolling a total of 42 infants and their mothers. The pilot study showed that infants experiencing FICare had higher weight gain and breastfeeding rates at discharge and FICare parents had lower stress and anxiety than controls.1 They followed up the pilot study with a cluster randomized controlled trial that took place between 2013 and 2015 and included infants born at 25 NICUs in Canada, Australia, and New Zealand. In 2018, the results were published showing that FICare improves infant weight gain, reduces parental stress and anxiety, and improves high-frequency breastfeeding rates.2 Recently, they also published an abstract and are working on a manuscript showing that FICare also improves infant neurodevelopmental outcomes.

The success of FICare has piqued the interest of NICUs around the world, many of whom have come to visit and learn from the Mount Sinai NICU. A national FICare Steering Committee was established to help standardize and disseminate information about FICare and enable the program to scale while still maintaining its integrity. In 2017, the FICare website and toolkit were

1 O’Brien, K. et al “A pilot cohort analytic study of Family Integrated Care in a Canadian neonatal intensive care unit” BMC Pregnancy Childbirth 2013;13Suppl1:S122 O’Brien, K. et al “Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster-randomised controlled trial” Lancet Child Adolesc Health 2018;2(4):245-254.

1910-Year Report

developed to enable the expansion of FICare in both Level 2 and Level 3 NICUs across Canada. Going forward, the team is working to both implement FICare for infants who need critical care and extend psychosocial and peer support for parents for a full year after infant discharge.

As FICare continues to grow, the Mount Sinai NICU is adding programs to help parents who are not able to be in the NICU as much as they wish. For example, in the past year a cuddler program has begun for infants whose parents cannot be present to hold them, and a reading program has been established where high school students read to infants in their family’s absence. Both holding infants and reading to infants in the NICU were reported to improve their neurodevelopmental outcomes.

PARENT EDUCATION AND PSYCHOSOCIAL SUPPORTEven before the implementation of FICare, the Department of Paediatrics was fully committed to patient and family-centered care. Our family programs are coordinated by a dedicated Parent Resource Nurse and Social Worker in partnership with a team of social workers, lactation consultants, nurses, physicians, respiratory therapists, and veteran parent volunteers. In the last three years, following the implementation of FICare, the family education and psychosocial support services have been re-vamped and grown to meet the changing needs of families.

Parent EducationThe Mount Sinai NICU has a vibrant parent education program. Parent classes happen daily and are scheduled by month. Classes are developed and led by a diverse group of NICU team members and cover a variety of topics relevant to preterm birth. Typically 10 to 12 parents attend each session and both current NICU parents and parents of recently discharged infants are welcome to attend.

Parent Buddy ProgramMore and more research shows that parental mental health is essential for the best infant and family outcomes. For this reason, parent psychosocial support is a key part of care in the Mount Sinai NICU. We have 3.0 full-time equivalent Social Workers and a dedicated Parent Resource Nurse in the NICU to help parents navigate the complex NICU environment and manage difficult care decisions for their infant. In addition, we have regular peer support groups for parents (both mothers and fathers) and the Parent Buddy Program.


The Parent Buddy Program was established in 1991 as a way to help parents manage the emotional complexity of having an infant in the NICU. Parent Buddies are parent volunteers who had an infant in the NICU, and they are matched with interested current NICU parents on the basis of their infant’s gestational age, weight, and situational criteria. There are currently about 50 Parent Buddy Volunteers and about 30% of NICU parents are matched at any given time. New Parent Buddies are trained twice a year using a Parent Buddy Training Program that was recently re-vamped by the social workers, Parent Resource Nurse, and Veteran Parent volunteers. Going forward the team is working to recruit more diversity in the volunteer pool for the Parent Buddy Program.

PARENT ADVISORY BOARDThe Mount Sinai NICU is proud of the active role Veteran Parents play in all aspects of the NICU operations. Veteran Parents were an integral part of the development and implementation of the FICare philosophy in the NICU, and they continue to play an important part the growth and development of our NICU community. The Parent Advisory Board, which has been in existence for over 20 years, is the primary mechanism for Veteran Parents to stay involved with the Mount Sinai NICU. In 2017, the Board reorganized and now has two co-chairs who manage the Board leadership. The Board has 50 members, but 10 to 12 primary members who meet once a month for two hours in the evening, and is supported by the social work lead and Parent Resource Nurse. The Board is responsible for reviewing parent documents and policies for the NICU, updating content on the display boards in the NICU, participating in research, holiday events in the NICU (e.g. Christmas, Mother’s Day, and Father’s Day), World Prematurity Day Events, Journey Beads and NICU Holiday Baskets with Handfull Hearts, Veteran Parent Picnic, and the quarterly newsletter for the Perinatal Parent Association (1200 former NICU parents).

2110-Year Report

CONTINUOUS QUALITY IMPROVEMENTThe NICU team at Mount Sinai is dedicated to working as an interdisciplinary team to continuously improve quality of care and is a national leader in quality improvement initiatives. In 2011, we established an Improving Quality Team to improve the safety and quality of care of NICU patients, families, and staff through communication, feedback, and ongoing education. A key addition to the Improving Quality Team was a Quality-Safety Nurse in the Evidence-based Practice for Improving Quality (EPIQ) program, a position Mount Sinai was the first to implement. The Quality-Safety Nurse works closely with the Quality Improvement lead, the site coordinator for the national EPIQ program, and the Mount Sinai Hospital Quality and Safety Council that is made up of 15 people (12 nurses, 1 medical lead, 1 respiratory therapist, and 1 lactation consultant).

Quality improvement at Mount Sinai focuses on 4 priorities:

There are weekly Quality Rounds for the whole NICU as well as biweekly Quality and Morbidity Rounds where the team reviews past actual and potential safety events, monitors trends, does root-cause analysis, and identifies potential solutions. In addition, in the past 5 years there have been many quality improvement initiatives that involve the whole unit, including promoting brain health, infection prevention, line bundle and new line configuration, delayed cord clamping to improve outcomes, preventing unplanned extubation, pressure injury prevention, device integration into the electronic medical records, and process improvements related to moving into a new unit.

Several of the quality initiatives in the Mount Sinai NICU were the first of their kind and highly successful. For example, the team earned an Accreditation Leading Practice award for their work establishing electronic surveillance of medical devices to prevent infection. Another project that earned an Accreditation Leading Practice award was an initiative that identified lack of visibility and awareness factors that contribute to unplanned extubations. The project led to new guidelines and reference materials outlining the best care practices for intubated infants that led to a more than 50% decrease in unplanned extubations. Last, the Mount Sinai NICU recently initiated and implemented a program that trains and certifies bedside nurses to insert central venous lines (PICC) in collaboration with the medical team. By enabling nurses to perform this essential task, infants no longer need to wait as long to have a PICC inserted. The consistency in the availability of PICC insertion expertise substantially reduced the number of infants referred to image guided therapy and reduced the number of PICC related infections.

HEALTH SYSTEMS

IMPROVEMENT

PATIENT EXPERIENCE

PATIENT SAFETY AND OUTCOMES

STAFF SATISFACTION


POINT-OF-CARE TECHNOLOGYTargeted Neonatal EchocardiographyTargeted neonatal echocardiography (TNE) is a point-of-care technology that uses cardiac ultrasound to assess cardiac function and blood flow in infants. When integrated with clinical signs, TNE helps guide therapeutic decisions in real time, which has the potential to refine care and improve outcomes. In 2011, we acquired state-of-the-art ultrasound equipment and recruited Dr. Amish Jain to start an in-house TNE service. Before TNE service was available at Mount Sinai Hospital, the echocardiography service had to be organized through the Hospital for Sick Children, including transfer of infants in some cases, which delayed infant diagnosis and increased the risk of complications. Since the in-house TNE service began in 2012, consults can be done at the infant’s bedside with reports available on the same day. Further, the clinicians are able to access clinical neonatal hemodynamic expertise on a day-to-day basis.

In addition to bringing the TNE service to Mount Sinai, Dr. Jain developed an imaging protocol that is now in use at Mount Sinai, Sunnybrook, and SickKids and is in the process of being adopted as a national guideline. He is working to expand the clinical and academic use of TNE across Canada and beyond by formalizing TNE training into a subspecialty fellowship program called the Neonatal Hemodynamic Fellowship.

Number of TNE Consults

2012 2013 2014 2015 2016 2017 2018

111 126 214 301 365 516 489

Lung UltrasoundLung ultrasound is an emerging point-of-care technology that has the potential to reduce the use of x-rays in infants by 50% while improving diagnostic sensitivity and specificity. Dr. Adel Mohammed and Dr. Yenge Diambomba spearhead lung ultrasound research and training in Sinai Health System. They analyze lung ultrasound images then make treatment recommendations based on the results. In addition, they are working to analyze the impact of the lung ultrasound program and define Canadian-specific guidelines for the lung ultrasound technology. To this end, Dr. Mohammed established the national Lung Ultrasound Committee to set guidelines and policy for implementing and using lung ultrasound.

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The Rogers Hixon Ontario Human Milk Bank at Mount Sinai Hospital has grown rapidly since it opened in 2013 under the leadership of Medical Director Dr. Sharon Unger and in partnership with the Hospital for Sick Children and Sunnybrook Health Sciences Centre. The Milk Bank opened with the goal of providing human milk to infants in the NICU born at less than 1250 grams. These infants are particularly fragile, and it has been shown that mother’s own milk improves both short and long-term infant health; however, only 30% of mothers with infants in the NICU have enough breast milk to exclusively feed their infant mother’s own milk. The Rogers Hixon Ontario Milk Bank has received a huge amount of support and enthusiasm from families, health care providers, and donor mothers alike, which has allowed the Milk Bank to grow much faster than expected. It now provides donor milk for infants born at less than 1800 grams and born at less than 34 weeks of gestation at 8 Level 3 NICUs and 29 Level 2 NICUs in Ontario. In addition, in 2016, Mount Sinai Hospital became the first hospital in Canada to make informed consent mandatory for infant artificial formula feeding rather than donor milk feeding.

ROGERS HIXON ONTARIO HUMAN MILK BANK

~70% of preterm infants in Ontario

require some donor milk

> 5000 Litres of donor milk

are dispensed each year

100-125 Litres of donor milk

are dispensed each week

> 2000 approved donors to date

8 Ontario Level 3 NICUs

receive donor milk

29 Ontario Level 2 NICUs

receive donor milk


The Milk Bank has enabled large-scale research projects analyzing the effectiveness of feeding preterm infants human milk. In 2016, Dr. Unger and her colleagues in the DoMINO study group published the results of a pragmatic randomized controlled trial showing that donor milk as a supplement to mother’s own milk provided significant protection against necrotizing enterocolitis with similar long-term neurodevelopmental outcomes.3 In a second publication in 2018,4 it was reported that the families of infants supplemented with donor milk lost significantly less time from paid work than those supplemented with formula when followed to 18 months’ corrected age. Also in 2018, the OptiMOM group published the results from a randomized controlled trial showing that, when infants are fed a diet of mother’s milk supplemented with donor milk as required, there is no advantage to using a fortifier that is human milk based compared to bovine based, a significant cost saving.5 Going forward, the Milk Bank team has funding to continue analyzing the benefits of human milk, including the long-term effects of receiving human milk (at 5 years of age), effect of human milk on the infant microbiome,6 ethics of donor milk,7 and an in-depth analysis of human milk biology.

NEONATAL DEVELOPMENTAL FOLLOW-UP CLINIC The Mount Sinai Neonatal Developmental Follow-Up Clinic was established in 2010 under the leadership of Dr. Edmond Kelly as Clinical Director. The clinic provides screening and diagnostic services for infants born at less than 30 weeks’ gestation or less than 1250 grams birth weight. In addition, infants who had laser therapy, chest shunts in utero, fetal therapies, congenital hernias, spina bifida or other complications are referred to the Follow-Up Clinic. The clinic staff includes two occupational therapists, a physical therapist, nurse, nurse practitioner, speech/language therapist, psychologist, psychiatrist, and clinic coordinator. Together, the staff works to diagnose high-risk infants with any adverse outcomes such as cerebral palsy, speech delays, autism, motor deficits, behavioral disorders, or learning disorders, as early as possible.

The Follow-Up Clinic enrolls over 300 infants a year, has an 87% average follow-up rate, and enters all infants into the Canadian Neonatal Follow-Up Network (CNFUN) database. Each infant visits the clinic at 4, 8, 12, 18, and 36 weeks’ corrected gestational age for screening. If a problem is identified the Follow-Up team connects patients with dieticians, community care access centres, speech and language specialists, or other specialist care, depending on the child’s needs. Since 2010, more than 2000 infants from the Follow-Up Clinic were included in CNFUN.

Data collected by the Follow-Up Clinic, both as part of CNFUN and for individual studies, are an important part of many research projects that assess neonatal care and its impact on neurodevelopmental outcomes. Some examples of characteristics or care processes that were analyzed for association with neurodevelopmental outcomes are surgical ligation for

3 O’Connor, D.L. “Effect of Supplemental Donor Human Milk Compared With Preterm Formula on Neurodevelopment of Very Low-Birth-Weight Infants at 18 Months: A Randomized Clinical Trial” JAMA 2016;316(18):1897-1905.4 Trang, S. “Cost-Effectiveness of Supplemental Donor Milk Versus Formula for Very Low Birth Weight Infants” Pediatrics 2018;141(3): pii: e201707375 O’Connor, D.L. “Nutrient enrichment of human milk with human and bovine milk-based fortifiers for infants born weighing <1250 grams: a randomized clinical trial” Am J Clin Nutr 2018;108(1):108-116.6 Butcher, J. “Independent of Birth Mode or Gestational Age, Very-Low-Birth-Weight Infants Fed Their Mother’s Milk Rapid-ly Develop Personalized Microbiotas Low in Bifidobacterium” J Nutr 2018;148(3):326-335.7 Kassirer Y. Implications for Orthodox Jewish families in the provision of mother’s own and donor milk for their very low birthweight infant. J Hum Lact 2014 Nov;30(4):402-4.

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patent ductus arteriosus, acute severe pulmonary hypertension following rescue treatment with inhaled nitric oxide, donor milk versus formula for very low birth weight infants, bevacizumab injections for retinopathy of prematurity, inhaled and systemic steroid exposure, Family Integrated Care, midazolam dose, maternal anti-Ro antibodies, slow fetal heart rate, prolonged dexamethasone therapy, and nutrient intake in the first two weeks of life.

In January 2018, the Follow-Up Clinic moved to new facilities where they have more space and easier access to transit. Moving forward the Follow-Up Clinic is working to incorporate new screening methods to detect autism earlier, and online screening for older children to eliminate barriers to follow up like long drives and parking costs. Last, given the impact parental mental health has on neonatal outcomes, the Follow-Up Clinic would like to incorporate screening for parental post-natal depression to actively promote whole family health as a way to improve infant outcomes.

9 Facebook chats

online hangouts

Discharge from the NICU is both an exciting and challenging time for families with infants born preterm. The transition home can be stressful and isolating for families and can contribute to parental mental health issues. Healthy, supportive parents are key to positive infant outcomes; therefore, in 2015, Dr. Jennifer Young, under the guidance of Dr. Shoo Lee and Dr. Karel O’Brien, and in collaboration with Healthy Start, Healthy Future, and Life With A Baby, established Life With A Preterm Baby. The mission of Life with A Preterm Baby is “to strengthen and build parent confidence by providing ongoing support to families of preterm babies.” Through a combination of online resources, annual symposiums, webinars, Facebook chats, and meet up events, Life With A Preterm Baby provides parents of preterm infants professional and peer support targeted to the challenges of parenting a child born preterm. Dr. Young is working to expand Life With A Preterm Baby to include regular peer support groups for parents throughout the city of Toronto.

6webinars meet ups

annual symposiums4 18 12

annual World Prematurity Day events


The Department of Paediatrics has experienced many changes in the last ten years, including the implementation of FICare, opening of the Rogers Hixon Ontario Human Milk Bank, moving into a new NICU with a mixed-acuity model, establishment of a NICU culture focused on continuous quality improvement, and the integration of new point-of-care technology. At the same time, the number of beds in the NICU increased, over 30 new nurses were hired, and more infants needing critical care (i.e. born with high SNAP-II [Score for Neonatal Acute Physiology-II] scores, at extremely low gestational ages, and with a low birth weight) were admitted to the NICU.

Outcomes

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018

Number of infants ≤ 32 weeks’ gestation

31 to 32 weeks’ gestation





500

400

300

200

100

0

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2009 2010 2011 2012 2013 2014 2015 2016 2017

35%30%25%20%15%10%

5%0%

2009 2010 2011 2012 2013 2014 2015 2016 2017

80%70%60%50%40%30%20%10%

0%

2009 2010 2011 2012 2013 2014 2015 2016 2017

9%8%7%6%5%4%3%2%1%0%

2010 2011 2012 2013 2014 2015 2016 2017

80%70%60%50%40%30%20%10%

0%

Infants with a SNAP II score > 20

Survival without morbidity rate

Mortality rate

Breastmilk only at discharge rate

Mount Sinai Hospital Canadian Neonatal Network





Since 2009, the Department of Paediatrics has rapidly

developed its research capacity and is now the most

productive research NICU in Canada. In addition to

physician researchers, our

Department also engages

Veteran Parents and non-

physician clinical staff in

research including nurses,

dieticians, pharmacists, social workers, and respiratory

therapists. Department members are leading or involved

in many studies including national and international large,

multicentre studies.

One key component of the research success of the

Department of Paediatrics is the support from the

Maternal-Infant Care Research Center (MiCARE), which

was established in 2009 by Dr. Shoo Lee. Funded

through research grants from CIHR and the Ontario

Ministry of Health and Long-Term Care, MiCare includes

4 PhD scientists and 13 other research staff to support

researchers in the Department. MiCARE is affiliated with

the Lunenfeld-Tanenbaum Research Institute, which

expanded to include clinical research in late 2014.

RESEARCH

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NEWBORN PHYSIOLOGYHemodynamics and Cardiac PhysiologyDr. Amish Jain is studying cardiac physiology of the newborn infant and refining the use of functional echocardiography in diagnosis and management of cardiovascular problems, particularly for those born preterm. Specifically, he is interested in understanding the pathophysiology and identifying the best practices for treatment of acute and chronic pulmonary hypertension, shock, and patent ductus arteriosus.

Hemodynamics and Brain FunctionDr. Poorva Deshpande is interested in monitoring the brain function and blood flow of preterm infants at the bedside. Her research integrates heart function assessment by echocardiography with continuous brain monitoring techniques such as near-infrared spectroscopy (IRS) and amplitude integrated electroencephalography (aEEG) to identify preterm infants at risk of brain injury.

Hemodynamics in Sepsis Dr. Ashraf Kharrat is using functional echocardiography to study neonatal hemodynamics in sepsis and septic shock. In addition she is working to integrate cardiopulmonary physiology findings into quality improvement initiatives that identify best care practices.

Research Areas


PATIENT-ORIENTED RESEARCHOutcomes Research and Evidence-Based MedicineDr. Prakesh Shah is a leader in evidence-based medicine, quality improvement, and systematic reviews. He is Director of the Canadian Neonatal Network™ (CNN) and both founder and Director the Canadian Preterm Birth Network (CPTBN), established in 2017, and the International Network for Evaluating Outcomes (iNEO) of neonates, established in 2012. All three neonatal networks collect population-based data on infants admitted to Level 3 NICUs and use the information for outcomes research, benchmarking, and comparative effectiveness research. Dr. Shah holds a Canadian Institutes of Health Research (CIHR) Applied Chair in Reproductive and Child Health Research.

Quality Improvement and Health Services ResearchDr. Shoo Lee is the Scientific Director of the Institute of Human Development, Child and Youth Health at the CIHR. Dr. Lee founded the Canadian Neonatal Network™ (CNN) in 1995 and developed and implemented the Evidence-based Practice for Improving Quality (EPIQ) method of quality improvement as an effective way to improve infant outcomes using data from CNN. EPIQ has transformed care in tertiary NICUs across Canada as well as in countries across the world.

Human Milk and NutritionDr. Sharon Unger is Medical Director of the Rogers Hixon Ontario Human Milk, founded in 2013, and is a leading member of a University of Toronto research team that is funded by CIHR to conduct studies on human milk and infant nutrition. In particular, Dr. Unger’s research focuses on analyzing the benefits of mother’s own milk versus formula, the microbiome in different kinds of human milk, the association of human milk with infant outcomes, and the biology of human milk.

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Family Integrated CareDr. Shoo Lee and Dr. Karel O’Brien developed and implemented a new care philosophy called Family Integrated Care (FICare) that integrates parents into their infants’ care teams. They recently completed an international cluster randomized controlled trial that showed improved infant weight gain, decreased parental stress and anxiety, and increased high-frequency breastfeeding in infants experiencing FICare. Building on their success, FICare is expanding into Level 3 and Level 2 NICUs across Canada and internationally. Dr. O’Brien is also working to assess whether infants who are critically ill can safely benefit from FICare.

Family Integrated Care HomeDr. Jennifer Young and Dr. Karel O’Brien are working to expand FICare support to families post-NICU discharge in a program called FICare Home. They are studying how timely referral to a home-visiting program for high-risk families and regular peer support targeted to families experiencing preterm birth can improve family function, parental stress, and infant health.

Pain ReductionDr. Vibhuti Shah uses her expertise in clinical trials and systematic reviews to investigate interventions that minimize infant pain. In addition, she is actively involved in the implementation of new evidence-based pain management practices.


Point-of-Care TechnologiesDr. Adel Mohammed and Dr. Yenge Diambomba are working to use lung ultrasound severity scoring as a diagnostic tool for the early prediction of bronchopulmonary dysplasia. In addition, they developed a lung ultrasound workshop to train clinicians across Canada how to use lung ultrasound. They are also studying the lung ultrasound implementation process and evaluating lung ultrasound training methods.

Neonatal Follow-UpDr. Edmond Kelly is the site leader for the Canadian Neonatal Follow-Up Network (CNFUN), which maintains a national database and is funded by CIHR to study neurodevelopmental outcomes of high-risk infants. He is actively involved in many studies associating care practices with adverse neurodevelopmental outcomes, including a recent study showing systemic steroid use before 4 weeks of age was associated with significantly worse neurodevelopmental outcomes.

EDUCATION RESEARCHNeonatal Resuscitation and Simulation TrainingDr. Emer Finan has been a member of the Canadian Paediatric Society (CPS) Neonatal Resuscitation Program (NRP) Steering Committee since 2010 and Chair since 2018. She has also been the CPS Liaison to the American Academy of Paediatrics NRP Steering Committee since 2018. As a member and, more recently, Chair of the CPS NRP Education Subcommittee, Dr. Finan actively contributed to the development of educational materials for the launch of the 6th and 7th editions of NRP in Canada. In addition, Dr. Kin Fan Young Tai is a NRP regional trainer who has facilitated and taught NRP instructor and provider courses to residents throughout University of Toronto health centres. Dr. Finan and Dr. Young Tai, along with Carol Chang, RN, conduct research on NRP procedures and ways to improve teaching of NRP including use of simulation techniques.

Curriculum Development and Trainee EvaluationAs Director of the Integrated Neonatal-Perinatal Training Program at the University of Toronto, Dr. Emer Finan is involved in the development of new training and assessment tools. In her role, she is working to implement competency-based medical education within the Division of Neonatology. Competency-based medical education focuses on training outcomes, which enables teachers to provide more effective and timely feedback to trainees while taking a learner-centered approach through the training stages.

The MiCare Research Centre was established at Mount Sinai Hospital in 2009 by Dr. Shoo Lee. The goal of MiCare, then and now, is to strengthen Mount Sinai’s, Ontario’s, and Canada’s health care system by improving the quality of care for newborn and paediatric patients.

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MiCare is a central data repository and analysis centre for all Canadian networks and hospitals that provide care for high-risk mothers and infants and one international neonatal network. Dr. Shoo Lee founded the Canadian Neonatal Network™ (CNN) in 1995 to collect data on characteristics, treatments, and outcomes for all infants admitted to Level 3 NICUs in Canada, and the database was then expanded to include the Canadian Neonatal Follow-Up Network (CNFUN), Canadian Neonatal Transport Network (CNTN) and Canadian Pediatric Surgery Network (CAPSNet). In 2012, Dr. Prakesh Shah established the International Network for Evaluating Outcomes of neonates (iNEO) to collect population-based outcomes data for infants <1500 grams birth weight in 11 Organisation for Economic Co-operation and Development countries, with MiCARE as the coordinating and data centre. In 2017, Dr. Prakesh Shah received CIHR funding to create the Canadian Preterm Birth Network (CPTBN), which expanded the Canadian neonatal database into a truly perinatal database that includes all high-risk pregnancies and engaged obstetricians and maternal fetal medicine specialists.

MATERNAL-INFANT CARE RESEARCH CENTRE (MICARE)


MiCare staff deliver essential research support services that enable high-caliber clinical research at Mount Sinai Hospital, throughout Canada and globally. MiCare researchers and biostatisticians provide expertise about study design and statistical analysis for perinatal-neonatal research projects as well as assist in the preparation of comparative reports for Ontario NICUs. MiCare database managers maintain the current network databases and facilitate data access, as well as provide advice on the design, development and management of research databases to other interested groups. Finally, writing and editing services help researchers prepare manuscripts for publications and apply for grants.

A key service provided by MiCare is benchmarking for the Mount Sinai NICU plus 30 Level 3 NICUs in Canada. Benchmarking is provided biannually and gives NICUs feedback on processes or outcomes they are targeting in their quality improvement initiatives. NICUs then use the benchmarking reports to adjust their initiatives in response to real-world data about the effect of the implemented changes. Benchmarking by MiCare is also used to evaluate new technologies and models of care like the targeted neonatal echocardiography service implemented in the NICU.

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RESEARCH PRODUCTIVITY AND AWARDSThe services described above along with high-caliber MiCare researchers have made MiCare Research Centre at Mount Sinai highly productive and effective.

2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 TOTAL

Abstracts 43 68 79 61 54 68 83 58 90 62 663

National Presentations 43 59 67 80 64 42 33 31 15 26 439

International Presentations 29 32 66 70 96 47 79 51 39 57 531

Awards and Honours 6 15 12 16 10 7 5 12 15 6 104

Publications 55 54 73 103 79 66 80 69 77 82 736

ANNUAL AMOUNT OF GRANT FUNDING

2009 $4,711,898

2010 $6,251,396

2011 $7,231,331

2012 $9,608,427

2013 $9,513,117

2014 $6,416,354

2015 $9,726,196

2016 $14,964,759

2017 $19,332,055

2018 $16,213,400

Total $103,968,934.48


Medical education stands on an equal footing with

clinical excellence and world-class research in the

Department of Paediatrics. The large volume of complex

clinical cases seen in the in-patient

and out-patient maternal, foetal,

and neonatal populations allows

the Department of Paediatrics to

provide state-of-the-art training to

multiple levels of learners in the NICU, Mother and Baby

Unit, Neonatal Developmental Follow-Up Clinic, and

Special Pregnancy Program Antenatal Clinic.

EDUCATION

3710-Year Report

Dr. Emer Finan, who holds a graduate degree in health professional education, is the Director of the Integrated Neonatal-Perinatal Fellowship Program at the University of Toronto. All faculty are involved in teaching during their clinical service months and also participate in undergraduate and postgraduate didactic teaching for medical trainees, graduate student teaching, and continuing medical education. In accordance with the high value the Department places on inter-professional education, nurses, respiratory therapists, pharmacists, dietitians, therapists and social workers are actively involved in didactic and clinical education of medical postgraduate trainees. The University of Toronto Neonatal-Perinatal Training Program has full accreditation status with the Royal College of Physicians and Surgeons of Canada.

Dr. Finan’s expertise, along with that of Dr. Ann Jefferies who retired in 2016, has allowed Mount Sinai Hospital to play a leadership role in postgraduate medical education and faculty development at the specialty and subspecialty levels at the University of Toronto, as well as nationally. Dr. Jefferies developed the current two-year curriculum for the perinatal-neonatal training program using Delphi methodology and Dr. Finan helped implement it in 2012. In addition, Dr. Jefferies co-led the development of both the Neonatal Structured Oral Exam and objective structured clinical examinations (OSCE) that were disseminated nationally and are used by virtually all training programs in Canada. Dr. Finan is currently involved in examination development for both the Neonatal Structured Oral and OSCEs. As a corresponding member of the Royal College Subspecialty Committee, Dr. Finan has contributed to the development of subspecialty specific standards of training and documents to guide both competency-based subspecialty training and assessment following the implementation of “Competence by Design” for neonatal-perinatal medicine in 2020.

Academic Year Paediatric Residents

Neonatal- Perinatal Fellows

Other U of T

Residents External Electives TOTAL

PGY1 PGY3 Residents Fellows

2009-2010 22 24 21 9 3 2 602010-2011 24 23 22 7 1 0 552011-2012 25 20 22 8 6 0 592012-2013 22 21 22 12 3 1 592013-2014 23 12 24 4 3 1 672014-2015 27 22 19 4 10 2 842015-2016 30 20 24 5 8 0 872016-2017 27 24 23 4 8 2 882017-2018 30 25 20 5 7 0 87

TOTAL 207 179 173 54 46 7 579

Academic Year Medical Midwifery Physician Observers TOTAL

2009-2010 6 3 5 142010-2011 9 3 1 132011-2012 5 5 13 232012-2013 2 3 2 72013-2014 8 3 2 132014-2015 1 6 12 192015-2016 0 4 10 142016-2017 1 3 10 142017-2018 0 5 16 21

TOTAL 24 32 69 125


RESIDENT TRAININGA majority of the trainees in the Department of Paediatrics are postgraduate trainees enrolled in accredited Royal College of Physicians and Surgeons training programs. Paediatrics trainees, like those enrolled in the University of Toronto Core Paediatrics program, do an 8-week mandatory rotation in postgraduate year (PGY1) in Neonatal-Perinatal Medicine. In addition, PGY1 trainees in Obstetrics and Gynecology, Medical Genetics and Paediatric Neurology, as well as PGY3 trainees in Core Paediatrics, have a 4-week mandatory rotation. The Department of Paediatrics reviews and enhances the training experience for residents each year under the past leadership of Dr. Ann Jefferies and Dr. Adel Mohamed and the current leadership of Dr. Poorva Deshpande. Between 2009 and 2018, dedicated experiences in the Mother and Baby Unit and Labour and Delivery Suite have been introduced along with skills and resuscitation training sessions and “mock codes.”

FELLOWSHIP TRAININGThe Department of Paediatrics also provides training to Neonatal–Perinatal Medicine subspecialty residents and fellows. Neonatal-Perinatal residents and fellows spend 1 to 3 months at Mount Sinai Hospital in both Years 1 and 2 of their programs and do rotations in both the Neonatal Developmental Follow-Up Clinic and antenatal consultation. Senior subspecialty Neonatal–Perinatal Medicine trainees have an opportunity to do a junior staff month at Mount Sinai Hospital. In addition, elective experiences are also provided for specialty and subspecialty residents from other Canadian centres each year. Fellows from around the world have joined our program including those from Canada, the United States, United Kingdom, United Arab Emirates, Palestine, Kuwait, India, Malaysia, Japan, Israel, Australia, Trinidad and Tobago, Egypt, Slovakia, Oman, Brazil, Spain, Switzerland, Jamaica and Saudi Arabia. The Department of Paediatrics strives to continuously improve the medical education it provides by continually responding to feedback from the subspecialty trainees regarding their educational experience.

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CLINICIAN-SCIENTIST TRAINING PROGRAMStarted by Dr. Shoo Lee in 2010, the Neonatal Clinician-Scientist Training Program is a new initiative with the goal of providing talented and motivated young neonatologists with extended research training required for a successful research career in either the clinical or basic sciences. Under this program, subspecialty trainees who have completed neonatal fellowship training are appointed as staff neonatologists at Mount Sinai Hospital while pursuing research training for up to 4 years. The program provides competitive salary support, structured mentorship and protected time for the pursuit of masters or doctoral-level research training at the University of Toronto.

SPECIALTY TRAINING Targeted Neonatal Echocardiography (TNE) Training ProgramFollowing the successful implementation of bedside TNE services in the Department of Paediatrics NICU, Dr. Amish Jain developed a TNE training program in collaboration with clinicians at the Hospital for Sick Children. The goal is to expand the use of TNE services to NICUs across Canada. Each year the program selects 2 applications from post-fellowship neonatologists who then spend 4 months in cardiology and 4 months in the Department of Paediatrics NICU. So far the program has trained 13 Canadians and 4 international neonatologists, which has resulted in the expanded use of TNE services in 13 NICUs across Canada.


Cardiopulmonary CourseIn addition to the TNE training program, Dr. Jain runs a cardiopulmonary course to teach clinicians and allied health professionals about cardiophysiology. Both neonatologists and cardiologists present over the 2-day course, and it has been well received. In 2017, there were 62 trainees and in 2018, there were 76 trainees.

Lung Ultrasound CourseAnother type of specialty training led by the Department of Paediatrics is lung ultrasound workshops. Dr. Adel Mohamed and Dr. Yenge Diambomba have the goal of training representatives from every NICU in Canada so that the lung ultrasound technology can be used to guide treatment decisions in all Canadian NICUs. They are using a “train-the-trainer” approach and selecting trainees who know how to use the ultrasound machine for the courses. They held two workshops in 2017, and one in 2018, which resulted in 89 trainees from 27 hospitals.

UNDERGRADUATE MEDICAL TRAINING As part of their curriculum, fourth year medical students from the University of Toronto attend a one-day neonatal teaching session. The session is conducted approximately 6 to 8 times per year and all Department of Paediatrics faculty participate in both the didactic and bedside components. Dr. Emer Finan and Dr. Jennifer Young represent the Division of Neonatology at the University of Toronto Paediatric Undergraduate Committee and led the development of the curriculum in both 2010 and 2018. In addition to students from the University of Toronto, medical students from other Canadian centres and abroad undertake electives in the NICU each year. Between 2009 and 2018, the Department of Paediatrics hosted students from Dominica, Hong Kong, Poland, Saudi Arabia, St. Maarten, Switzerland, and the UK.

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NURSE AND RESPIRATORY THERAPIST TRAININGCare practices in the NICU are always evolving and providing training to over 200 nurses and 50 respiratory therapists is challenging. There have been many innovations in NICU care that required staff training over the last 10 years including new bedside monitors and computers, computerized order entry, a milk tracking system, mixed-acuity model of care, pressure sore and infection prevention bundles, FICare, a new protocol for extremely low birth weight infants, electronic infusion management, and revision of protocols monitoring intubated infants. In all instances we used creative strategies to educate and train our staff, including using the “train-the-trainer” method, our learning café, weekly education emails, cases studies, and education sessions called “Neo on the fly”.

NursesAll nurses in the Department of Paediatrics who are new to the NICU environment participate in 360 hours of comprehensive classroom and bedside training that is followed up at 3, 6, 12, and 18 months. The training includes a combination of classroom, immersive simulation, and supervised shifts to help new staff become independent NICU nurses. Orientation sessions, which occur every few months, consist of in-class presentations from all disciplines, including a session from our Parent Partner and Veteran Parents. Three months of supervised shifts allow nurses to experience the NICU, learn the additional skills they need, and gain confidence. Through their onsite training, new nurses work their way from novice to expert with the support of the Nurse Clinician, Clinical Nurse Specialist, and their colleagues. In addition to nurses new to the NICU, we provide nursing education for nursing students, nurses attending a perinatal course, and nurses working on upgrading their NICU skills. In addition, we provide training for peripheral central catheter insertion, transport nurses, nurses to work in the resuscitation room, and nurses to work as team leaders.

Respiratory TherapistsThere are two types of respiratory therapists at Mount Sinai Hospital: generalists and core therapists. All respiratory therapists have proficiency for service, but core therapists are in the NICU and Mother and Baby Unit 80 to 100% of the time. Respiratory therapist training occurs throughout the year depending on the hiring of new staff, maternity leave and promotion of existing staff to NICU respiratory therapist core status. For the generalist training program, respiratory therapists are provided with a training resource manual and spend a minimum of two weeks precepting with a NICU Core Respiratory Therapist. After the initial training, the respiratory therapist will then work a series of shifts within the NICU environment where they manage a caseload with assistance, guidance and support from the Resource Respiratory Therapist and the rest of the NICU team. The core therapist training can take up to a year and provides a respiratory therapist with a minimum two years of critical care experience and the opportunity to acquire skills in neonatal intubation, mentorship, advanced ventilation strategies, newborn assessment, and advanced respiratory support and stabilization.


In addition to their own training, respiratory therapists provide important training for staff from many different disciplines in the NICU including respiratory therapy students who need to achieve competency, paediatric residents who need training every 4 weeks, family practice residents who train for a week at a time throughout the year, nursing students and new nursing staff, midwives, transport team members, and paramedics. Respiratory therapists are also actively involved in training for the Neonatal Resuscitation Program Certification and weekly CPR training for parents.

INTER-PROFESSIONAL EDUCATIONIn accordance with the importance the Department puts on inter-professional education, nurses, respiratory therapists, pharmacists, dietitians, therapists and social workers also provide teaching for all health care professionals. The Department offers a 2-week elective for midwifery students from Ryerson and Laurentian Universities. In addition, physicians from all over the world come to spend time in the department to observe the care we provide. From 2009 to 2018, physicians from Australia, Brazil, Egypt, India, Japan, Peru, and Trinidad and Tobago visited the Department.

Neonatal Resuscitation ProgramThe Neonatal Resuscitation Program is mandatory for all staff working in the NICU and must be completed every two years. For this reason, the Neonatal Resuscitation Program has been instrumental in bringing nurses, physicians and respiratory therapists together as instructors to provide inter-professional teaching, ongoing curriculum development and ongoing opportunities for simulation-based learning. This training program has also enabled the formation of relationships with other departments beyond the NICU including team members from the antenatal, labour and delivery, midwifery and post-partum areas of the Women’s and Infants’ Health program.

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INTERNATIONAL TRAINING PROGRAMSInternational Training Program in Neonatal-Perinatal Medicine in ShanghaiLaunched in April 2004 by Dr. Shoo Lee and Dr. Yonghao Gui, the International Training Program in Neonatal-Perinatal Medicine in Shanghai is a joint venture of the Canadian Neonatal Network™ and the Children’s Hospital of Fudan University in Shanghai. The program was endorsed by the Canadian Pediatric Society, funding was provided by China, and it creates unprecedented new opportunities for collaboration between Canadian and Chinese doctors and hospitals. The objectives of the program are to form a national training center in neonatal-perinatal medicine in Shanghai, establish national standards for training neonatologists in the People’s Republic of China, and upgrade standards of care and training at the Children’s Hospital of Fudan University in Shanghai.

The curriculum and standards for the 2-year training program follow those of the Royal College of Physicians of Canada for sub-specialty training in neonatal-perinatal medicine. Selected trainees from across the People’s Republic of China train for a year in Shanghai with Canadian clinicians, who stay and instruct trainees for a month at a time. After a year of training in Shanghai, trainees complete a year of neonatal sub-specialty training in Canada. To date, the program has trained over 100 neonatologists from 34 cities in 28 provinces across China and is considered the top training program in the People’s Republic of China. Eleven of our former trainees now hold senior administrative positions in their NICU or hospital.

International Training Program in Neonatal-Perinatal Nursing in ShanghaiStarted in 2005 by Dr. Shoo Lee, this program is the nursing equivalent of the International Training Program in Neonatal-Perinatal Medicine. Each year, nurses from all across the People’s Republic of China enroll in the program at the Children’s Hospital of Fudan University. A team of 2 nurses or respiratory therapists from Canada provides 2 months of intensive training in Shanghai. Trainees then attend 1 to 3 months of hands-on training at Canadian NICUs before returning home. The program is highly regarded in China, over 36 nurses have been trained so far, and there is lack of capacity to accommodate all the applicants each year.


The Goldman Family for the incubators and RetCam

The Kimmel Family for the lung ultrasound

The Osbourn Family for money towards a milk bank study

The Rogers and Rottman Families for milk bank donations

Cameron Strollate, a NICU grad, for money for ventilators

Lillian Laconte, a NICU grad, for her continuous support through

“Cherished Creations”

Newton Glassman Funds

BloombergSen Investment Partners

Export Packers Company Limited

Fantasy Creations

The Gerald Schwartz and Heather Reisman Foundation

The Jay & Barbara Hennick Family Foundation

The Rotman Family Foundation

Sandra Schmirler Foundation

Silver Family Charitable Foundation

Terra Tundra Foundation

United Way of Greater Toronto

DONORS

The Department of Paediatrics

continues to experience a high level

of support through private donations

from family members whose lives we

have touched and other interested

supporters and organizations. We

would like to say a huge thank you to

all those who made a donation from

2009 to 2018 with particular thanks

to the following:

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Professional Highlights• Dr. Shoo Lee was appointed Scientific Director of the Institute of Human

Development, Child and Youth Health at the Canadian Institutes of Health Research and Honorary President of the Xiamen Children’s Hospital. He also received the Doctorat Honoris Causa from Laval University in Quebec and the Magnolia Gold Award from the Municipal Government of Shanghai.

• Dr. Prakesh Shah received a CIHR Applied Chair in Reproductive and Child Health Research and was promoted to Full Professor, appointed Director of the Canadian Neonatal Network™ (CNN) and the International Network for Evaluation of Outcomes in neonates (iNeo), and founded the Canadian Preterm Birth Network (CPTBN).

• Dr. Sharon Unger was appointed Medical Director of the Rogers Hixon Ontario Human Milk Bank, promoted to Associate Professor, and received a CIHR Foundation Grant.

• Dr. Emer Finan was appointed Director of the University of Toronto Neonatal-Perinatal Fellowship Program.

• Dr. Amish Jain received his PhD, was appointed Director of the Targeted Neonatal Echocardiography (TNE) Program and was promoted to Associate Professor.

• Dr. Karel O’Brien received her MEd and was promoted to Associate Professor.

• Dr. Poorva Desphande received her MSc and was promoted to Assistant Professor

• Dr. Adel Mohamed and Dr. Jennifer Young received their Graduate Diploma in Clinical Epidemiology and were promoted to Assistant Professor

• Dr. Vibhuti Shah and Dr. Ann Jeffries were promoted to Full Professor

PEOPLEThe last 10 years have been a time of

many changes and accomplishments.

We are very proud of our colleagues and

would like to congratulate our members

on the following accomplishments:

4710-Year Report

Physicians and Faculty ResearchersPoorva Deshpande, MBBS, MSc Staff Neonatologist, Assistant Professor

Dr. Deshpande is a Staff Neonatologist and Neonatal Clinician Scientist with research interests in cerebral hemodynamics and using near-infrared spectroscopy to assess brain function in at-risk infants.

Yenge Diambomba, MD, FRCPCStaff Neonatologist, Clinical Director of Nurseries, Assistant Professor

Dr. Diambomba is the Clinical Director of Nurseries and has the goal to provide the best patient-focused, individualized care for all infants. She focuses on inter-professional teamwork and initiating and facilitating clinical practice changes that improve care. Her research interests are in point-of-care lung ultrasound and organizational research.

Emer Finan, MB, DCH, Med, MRCPIStaff Neonatologist; Assistant Professor; Director, Neonatal-Perinatal Medicine Training Program, University of Toronto

Dr. Finan is the Director of the Neonatal-Perinatal Training Program at the University of Toronto and is interested in the education and practical skills training of clinicians. Her research focuses on use of simulation in training.

Amish Jain, MBBS, MRCPCH, PhDStaff Neonatologist, Associate Professor

Dr. Jain is a Staff Neonatologist and Clinician Scientist with an interest in pulmonary hypertension and heart physiology. He heads the bedside TNE program in the Mount Sinai NICU and is working on improving treatment and diagnostic techniques for pulmonary hypertension.

Edmond Kelly, MB, BCh, BAC, FRCPCStaff Neonatologist; Associate Professor; Clinical Director, Neonatal Developmental Follow-Up Clinic

Dr. Kelly is the Clinical Director of the Neonatal Follow-up Clinic, and his research interests include the long-term outcomes of high-risk preterm infants.

Ashraf Kharrat, MDStaff Neonatologist, Assistant Professor

Dr. Kharrat is a Staff Neonatologist in the NICU. She has a clinical and academic interest in bridging cardiopulmonary physiology with quality improvement and is currently undertaking research in neonatal hemodynamics in sepsis and septic shock.


Maksim Kirtsman, MDCM, FRCPC, FAAPStaff Neonatologist, Lecturer

Dr. Kirtsman is a Staff Neonatologist in the NICU and antenatal clinic. He has an interest in process improvement, quality improvement, and developing quality improvement curricula.

Shoo Lee, MBBS, FRCPC, PhD, DHCPaediatrician-in-Chief; Professor; Director of MiCare; Scientific Director, Institute of Human Development, Child & Youth Health, Canadian Institutes of Health Research

Dr. Lee’s research interests focus on improving quality of care, patient outcomes, and health care services delivery. He founded the Canadian Neonatal Network, developed the Evidence-based Practice for Improving Quality method and has many national and international awards for his work.

Tom Leibson, MDAcademic Paediatrician, Assistant Professor

Dr. Leibson is a Staff Pediatrician in the Mother-Baby Unit and Post-Natal Ambulatory Clinic. He has an interest in neonatal clinical pharmacology and is providing consultations regarding potential outcomes of drug exposure during pregnancy and breastfeeding

Adel Mohamed, MD, MScStaff Neonatologist, Assistant Professor

Dr. Mohamed is a Staff Neonatologist with interests in improving quality of care and implementing the use of new technologies. He created the national Lung Ultrasound Committee and designed and runs a lung ultrasound training program with the goal of implementing the use of lung ultrasound technology at all 31 NICUs in Canada.

Karel O’Brien, MD, MB, BCh, BAO, FRCPCStaff Neonatologist, Associate Professor

Dr. O’Brien is a Staff Neonatologist and Clinician Scientist with an interest in improving infant outcomes by incorporating families into infant care. She led an international clinical trial of Family Integrated Care (FICare) in tertiary NICUs and continues to work towards implementing FICare in all Canadian NICUs.

Xiangming Qiu, PhDHealth Services Researcher, Assistant Professor

Dr. Qiu is interested in educational and psychological outcomes focusing on prevention and intervention practices, health services research, and international medical education. She is working with an integrated team of stakeholders to better support families of preterm infants following discharge from the NICU.

4910-Year Report

Kin Fan Young Tai, MBBS, MHSc, FRCPCStaff Neonatologist, Assistant Professor

Dr. Young Tai is a Staff Neonatologist with interests in education, neonatal resuscitation training and quality improvement. She is on the Neonatal Resuscitation Committee and and teaches neonatal resuscitation courses throughout the year. In addition, she reviews all resuscitation records to improve quality of care.

Jyotsna Shah, MBBS, MDStaff Paediatrician, Assistant Professor

Dr. Shah is a Staff Paediatrician who focuses on care in the Mother and Baby Unit and the Post-Natal Ambulatory Clinic. Her special interests are improving the quality of care provided to mothers and newborn infants, especially promoting breastfeeding as an exclusive diet for newborns.

Prakeshkumar Shah, MD, MSc, FRCPC, MRCPCHStaff Neonatologist, Professor, Associate Director of MiCare, and Director of CNN and iNeo

Dr. Shah is a Staff Neonatologist, Clinician Scientist, and Director of the Canadian Neonatal Network™ and International Network for the Evaluation of Outcomes. His research interests focus on improving infant outcomes through comparative effectiveness research and quality improvement initiatives.

Vibhuti Shah, MBBS, DCH, MD, FRCPC, MScStaff Neonatologist, Professor

Dr. Shah is a Staff Neonatologist and Clinician Scientist with experience in epidemiology, systematic reviews, knowledge translation and implementation of practice change. She is primarily interested in pain management in neonates and quality improvement initiatives.

Sharon Unger, MD, FRCPCStaff Neonatologist; Associate Professor; Medical Director, Rogers Hixon Ontario Human Milk Bank

Dr. Unger is a Staff Neonatologist, clinician scientist, and Medical Director of the Rogers Hixon Ontario Human Milk Bank. She leads clinical trials that investigate the biology of human milk and the impact of human milk diets on preterm infant outcomes.

Jennifer Young, MBBS, DMStaff Neonatologist, Assistant Professor

Dr. Young is a Staff Neonatologist with an interest in epidemiology and Family Integrated Care. Her research focuses on helping families transition from the NICU to home. She is developing community supports for parents following infant discharge from the NICU.


2017/2018Adrienne Bischoff (17/18)Ashley Blagdon (17/18)Mohamed Ibrahim (17/18)Maher Shahrour (17/18)

2016/2017Stefani Doucette (16/17, 17/18)Jessica Duby (16/17, 17/18)Sara Elias (16/17, 17/18)Jarred Garfinkle (16/17, 17/18)Beate Grass (16/17, 17/18)Srinath Krishnappa (14/15, 15/16, 16/17)Tapas Kulkarni (16/17, 17/18)Mei Ling Lee (16/17)Laura Prado (16/17, 17/18)Sally Mashally (16/17, 17/18)Carmen Rhoden (16/17, 17/18)Lana Shaiba (16/17, 17/18)Ranjeet Torgalkar (16/17, 17/18)

2015/2016Sally Abdelsalam (15/16)Eman Al Ansari (15/16)Marina Castro (15/16, 16/17, 17/18)Natalie Chan (15/16, 16/17)Kate Hodgeson (15/16)Ashraf Kharrat (15/16, 16/17, 17/18)Phoebe Kigozi (15/16, 16/17, 17/18)Elaine Neary (15/16, 16/17, 17/18)Kamini Raghuram (15/16, 16/17, 17/18)Carolina Sanguos (15/16, 16/17)Judy Seesahai (15/16, 16/17)Jonathan Wong (15/16)

2014/2015Mohamed Ahmed (14/15, 15/16)Hilal Al Mindhari (14/15, 15/16)Eric Ang (14/15, 15/16)Amir Atawna (14/15, 15/16)Mariam Ayed (14/15)

Neonatal-Perinatal Medicine Fellows

Clinician-Scientist TraineesDr. Afif EL-Khuffash, MD, currently at University of Dublin

Dr. Sandra Leibel, MD, PhD, currently at University of California-San Diego

Dr. Amish Jain, MD, PhD, currently at Mount Sinai Hospital

Dr. Connie Williams, MD, currently at McMaster University

Dr. Poorva Deshpande, MD, MSc, currently at Mount Sinai Hospital

Dr. Ashraf Kharrat, MD, current trainee

5110-Year Report

Amina Benlamri (14/15, 15/16, 16/17)Michael Castaldo (14/15)Regan Giesinger (14/15)Kristen Godin (14/15)Abu Ismail (14/15, 15/16)Hiroko Iwami (14/15, 15/16)Johannes Letschwiti (14/15, 15/16)Jyothsna Purna (14/15, 15/16, 16/17)Amy Shafey (14/15)Miroslav Stavel (14/15)Karen Thomas (14/15, 15/16)Mong Tieng Ee (14/15, 15/16)Mudita Tiwari (14/15)

2013/2014Michael Castaldo (13/14)Amir Elmekkawi (13/14)Kristen Godin (13/14)Abu Ismail (13/14)Hiroko Iwami (13/14)Jyothsna Purna (13/14)Asaph Rolintsky (13/14)Amy Shafey (13/14)Miroslav Stavel (13/14)Jonathan Wong (13/14)

2012/2013Mairam Ayed (12/13, 13/14)Mong Tieng Ee (12/13, 13/14)Regan Giesinger (12/13, 13/14)Yair Kasirer (12/13, 13/14)Jaideep Kanungo (12/13, 13/14)Amy Keir (12/13, 13/14)Deepak Louis (12/13, 13/14)Pankaj Sakhuja (12/13)Marlon Timothy (12/13, 13/14)

2011/2012Dalal Abdelgadir (11/12, 12/13, 13/14)Motee Abu Awwad (11/12, 12/13, 13/14)Maksim Kirtsman (11/12, 12/13)Amit Mukerji (11/12, 12/13, 13/14)Julia Panczuk (11/12, 12/13, 13/14)Asaph Rolintsky (11/12, 12/13)Navneet Sharma (11/12, 12/13)Wissam Shalish (11/12, 12/13)

2010/2011Poorva Deshpande (10/11, 11/12, 12/13)Enas El Gouhary (10/11, 11/12)Cecilia Herbozo (10/11, 11/12)Tetsuya Isayama (10/11, 11/12, 12/13)Woe Bing Poon (10/11, 11/12)Edward Pugh (10/11, 11/12)Jennifer Twiss (10/11, 11/12, 12/13)Payam Vali (10/11, 11/12)Dany Weisz (10/11, 11/12, 12/13, 13/14)

2009/2010Meijian Zhao (10/11, 11/12)Haydi Al Wassia (09/10)Nadya Ben Fadel (09/10)Christine Drolet (09/10)Julia Edwards (09/10)Omer Hamud (09/10)Ana Teresa Leslie (09/10)Mohit Sahni (09/10)Abd Elazeez Shabaan (09/10)Jennifer Young (09/10)Haythem Al-Khawaja (09/10, 10/11)Eyad Al Midani (09/10, 10/11)Mai Al-Qubaisi (09/10, 10/11, 11/12)Suhair Al-Shanteer (09/10, 10/11)Afif El Khuffash (09/10, 10/11)Julie Emberely (09/10, 10/11, 11/12, 12/13)Amish Jain (09/10, 10/11)Emad Khadawardi (09/10, 10/11)Faiza Khurshid (09/10, 10/11, 11/12)Jillian Lewis (09/10, 10/11)Adel Mohamed (09/10, 10/11)Jessie Van Dyk (09/10, 10/11, 11/12)


2017/2018Maura Ferrari Resende Mansur (17/18)Yan Mo (17/18)Ahmed Mustafa (17/18)Maura Resende (17/18)Elizabeth Stockley (17/18)Eyal Yacobi (17/18)Vincent Ye (17/18)

2016/2017Mohamed Ahmed (16/17, 17/18)Ameer Aslam (16/17)Frank Fusch (16/17)Mohamed Ibrahim (16/17)

2015/2016Latifa Abdullah Mohammed Al Mutawa (15/16)Arjun Dey (15/16, 16/17)Amy Shafey (15/16)Vivek Shukla (15/16, 16/17)Roukeyan Tuerxun (15/16, 16/17)Tiantian Xiao (15/16)

2014/2015Marina Castro (14/15)Shixiao Dong (14/15)Srinath Krishnappa (14/15)Zhiqiang Liang (14/15)Deepak Louis (14/15, 15/16)Aiman Surak (14/15)

Jyotsna Shah (14/15)Ranjit Torgalkar (14/15)

2013/2014Ranjit Torgalkar (13/14)Marina Castro (13/14)Srinath Bethamangala-Krishnappa (13/14)

2012/2013Sehr Ansari (12/13, 13/14)Eyad Daoud (12/13)

2011/2012Jia Li (11/12)Mingyan Hei (11/12)Colleen Doherty (11/12)Jyotsna Shah (11/12, 12/13, 13/14)Sladjana Bulatovic (11/12, 12/13)

2010/2011Hamid Hakak (10/11, 11/12, 12/13)Wegdan Mawlana (10/11)Yuan Li (10/11)Xuaoying Li (10/11)

2009/2010Qian-Shen Zhang (09/10)Meijan Zhano (09/10)Poorva Deshpande (09/10)Ilana Magder (09/10)

Departmental Fellows

Clinical Nurse Specialists and Nurse PractitionersCarol Chen Lesley Di-Fonzo Janet Narciso

Department of Paediatrics Support StaffBridget Joy James, Senior SecretaryNicole Brown, Senior SecretaryAmuna Yacob, Manager, Administrative ServicesMay Lee, Information Coordinator, Neonatal Developmental Follow-Up ClinicElena Nikolaeva, Database AssistantAngela Lim, Billing Clerk Carlena St. Brice, Medical Secretary

5310-Year Report

Maternal-Infant Care Research CentrePriscilla Chan, CNN and iNEO Project CoordinatorJosephine Hsieh, Project CoordinatorSarah Hutchinson, Scientific WriterValentina Ly, Research AssistantSukhy Mahl, Program ManagerNerizza Matignas, Office CoordinatorAmara Rivero, Senior Application DeveloperPrakesh Shah, Associate Director of MiCareCharlene Wong, EPIQ and CPTBN Project CoordinatorJunmin Yang, StatisticianYujin Yang, Application DeveloperPhilip Ye, StatisticianCynthia Yeh, Assistant Director of MiCareSonny Yeh, IT ManagerEugene Yoon, Statistician


2018Asbury M (Supervisor: Unger S). Ontario Graduate Scholarship Program, University of Toronto.

Lee SK. Datok Lim Nyok Ling Memorial Lecture, Perinatal Society of Malaysia.

McGee M (Supervisor: Unger S). Thesis Competition Provincial Finalist, University of Toronto.

McGee M (Supervisor: Unger S). Research Day Award Winner for Best Oral Presentation, Division of Neonatology, University of Toronto.

Pitino M (Supervisor: Unger S). Research Day Award Winner for Best Oral Presentation, Division of Neonatology, University of Toronto.

Sharma S (Co-Supervisor: Unger S). Ontario Graduate Scholarship Program, University of Toronto.

2017Asbury M (Committee member: Unger S). Finalist, Emerging Leader Research, Experimental Biology Annual Meeting, Chicago, Illinois.

Castro M (Supervisor: Unger S). Finalist, Fellow’s Oral Presentation of Research, Canadian Nutrition Society Annual Meeting, Toronto, Ontario.

Castro M (Supervisor: Unger S). Winner, Best Oral Presentation, Annual Research Day, Division of Neonatology, University of Toronto.

Jain A. Jack Kraicer Award for Research Excellence in Doctoral Studies, Department of Physiology, University of Toronto.

Jarde A (Supervisor: Shah P). SOGC Junior Members Obstetrics Poser Presentation Award, Society of Obstetricians and Gynecologists of Canada 73rd Annual Clinical and Scientific Conference, Ottawa, Ontario.

Kharrat A. Neonatal Cardiopulmonary Biology Young Investigators Forum 2017.

Lee SK. Doctorats Honoris Causa in Medicine, University of Laval, Quebec.

Lee SK. 2017 Founder’s Lecture, British Association of Perinatal Medicine.

Liu X (Supervisor: Lee S). 2017 Overseas Scholarship, People’s Republic of China Government.

Long L (Supervisor: Lee S). 2017 Overseas Scholarship, Urumqi Government.

Mellor K (Co-Supervisor: Shah P). Winner, Best Poster Presentation Award, 15th Annual Division

of Neonatology Research Day, University of Toronto.

Shah P. Research Mentorship Excellence Award, Neonatal-Perinatal Medicine Fellowship Training Program, University of Toronto.

Sharma S (Committee member: Unger S). Winner, Best Poster, Annual Research Day, Division of Neonatology, University of Toronto.

Sharma S (Committee Member: Unger S). Winner, Best Poster in the Junior Basic Science Category, Annual Research Day, Department of Paediatrics, University of Toronto.

Sharma S (Supervisor: Unger S). Research Day Undergraduate Award for Best Poster, Department of National Sciences, University of Toronto.

2016Ahmed M (Supervisor: Shah P). Winner, Best Poster Presentation Award, 14th Annual Neonatal-Perinatal and Maternal Fetal Medicine Research Day, University of Toronto.

Ahmed M (Supervisor: Shah P). Senior Trainee Clinical Research Award, Annual Department of Pediatrics Research Day, University of Toronto.

AWARDS AND HONOURS

5510-Year Report

AWARDS AND HONOURS

Finan E. Division of Neonatology Fellowship Training Program Career Mentor Award, University of Toronto.

Isayama T (Supervisor: Shah P). Pediatric Academic Society Travel Award.

Jain A. Award for Teaching Excellence, Neonatal-Perinatal Medicine Training Program, University of Toronto.

Lee SK. Douglas K. Richardson Award for Lifetime Achievement in Perinatal & Pediatric Healthcare Research, Society for Pediatric Research.

Lee SK. Honorary Member Award, EPIQ Latino.

Lee SK. Appointed as Honorary President of the Xiamen Children’s Hospital, Fujian, People’s Republic of China.

Lee SK. Contribution to Child Health Award, Canadian Association of Pediatric Health Centres.

Qi Z (Supervisor: Lee SK). 1st Prize Poster Presentation, 11th International Breastfeeding and Lactation Symposium, Berlin, Germany.

Sy S (Supervisor: Lee SK). Summer Studentship Award, Lunenfeld-Tanenbaum Research Institute.

Trang, S (Supervisor: Unger S) Finalist in Fellow’s Oral Presentation of Research, Canadian Nutrition Society Annual Meeting, Toronto, Ontario.

2015D’Souza R (Supervisor: Shah P). Gillian Hawker Best PhD CEHCR Poster Award, Institute of Health Policy, Management and Evaluation Annual Research Day, University of Toronto.

Diambomba Y. Karen McGibbon Award Excellence in Interprofessional Team Participation, Mount Sinai Hospital, Toronto, Ontario.

Kharrat A. Special Recognition Award for Excellence in All CanMEDS Competencies, CEO.

Kharrat A. Resident Spotlight Award, CHEO Paediatrics Residency.

Shafey A (Supervisor: Shah P). Senior Trainee Clinical Research Award, Annual Department of Paediatrics Research Day, University of Toronto.

2014Keir A (Supervisor: Shah P). Fred and Jane Bryans Trainee Award, Canadian Neonatal Perinatal in Banff, Alberta.

Lee SK. Toronto’s Top Doctors, Toronto Life.

Lee SK. Contribution to Child Health Award, Canadian National Perinatal Research Meeting in Banff, Alberta.

Lv Y (Co-Supervisor: Shah P). Pediatric Academic Society Travel Award.

Jain A. Bigelow Book Prize, Cardiovascular Sciences Collaborative Program, Faculty of Medicine, University of Toronto.

Jain A. Finalist for Award for Teaching Excellence, Neonatal-Perinatal Medicine Training Program, University of Toronto.

Panczuk J (Supervisor: Unger S). Winner, Best Oral Presentation, Annual Research Day Award, Division of Neonatology, University of Toronto.

2013Chiarelli L (supervisor: Shah P). Third place award, Annual Research Day, Department of Biostatistics, University of Toronto.

Jain A. Infection Prevention Safety and Performance Award, Mount Sinai Hospital Patient Safety and Quality Committee of the Board, in collaboration with Infection Control and the Office of Patient Experience and Outcomes, Mount Sinai Hospital.

Jain A. Abstract on neonatal transition selected by Canadian Thoracic Society (CTS) among the top 30 abstracts from Canada, American Thoracic Society.

Jan A. Award for teaching excellence, Neonatal-Perinatal Medicine Training Program, University of Toronto.

Jain A. POWER Teacher Award, Department of Paediatrics, University of Toronto.

Kumar P. Second prize for the best thesis in Paediatrics, Indian Journal of Paediatrics.

Kumar P. Wiley Blackwell First Prize at the International Congress of Paediatrics, 2013.

Lee SK. William Tooley Visiting Professorship, University of California San Francisco.

Lee SK. Karen McGibbon Award of Excellence awarded to the Rogers Hixon Ontario Human Milk Bank for Excellence in Innovation, Mount Sinai Hospital.

Lee SK. Infection Prevention Safety and Performance Award, Mount Sinai Hospital Patient Safety and Quality Committee of the Board, in collaboration with Infection Control and the Office of Patient Experience and Outcomes, Mount Sinai Hospital.

Lee SK. Achievement, Commitment and Excellence (ACE) Award, Ontario Ministry of Health and Long-Term Care.

Lee SK. Visiting Professorship, Wuxi Medical Centre, Jiangsu, People’s Republic of China.

Lyu Y (supervisor: Lee SK). Beijing Municipal Government Overseas Scholarship Award.

Rejiafu N (supervisor: Lee SK). Urumqi Government Overseas Scholarship Award.

Shah P. Infection Prevention Safety and Performance Award, Mount Sinai Hospital Patient Safety and Quality Committee of the Board, in collaboration with Infection Control and the Office of Patient Experience and Outcomes, Mount Sinai Hospital.

Unger S. Achievement, Commitment and Excellence (ACE) Award, Ontario Ministry of Health and Long-Term Care.


Unger S. Award for Outstanding Clinical Contribution for Clinical Excellence in Pediatric Medical Care, University of Toronto.

Unger S. Karen McGibbon Award of Excellence awarded to the Rogers Hixon Ontario Human Milk Bank for Excellence in Innovation, Mount Sinai Hospital.

2012El-Khuffash A. Winner of Best Neonatal Platform Presentation at the 11th Annual Neonatal and Maternal Fetal Medicine Research Day, Toronto.

El-Khuffash A. School of Graduate Studies Conference Grant.

El-Khuffash A. PAS Young Investigator’s Travel Awards Program.

Jain A. 2nd Place Gerald P Turner Best Practice Award, Mount Sinai Hospital.

Jain A. Queen Elizabeth II/Heart & Stroke Foundation of Ontario Graduate Scholarship in Science and Technology Award, University of Toronto.

Jain A. Travel Award, School of Graduate Studies, University of Toronto.

Ko G (supervisor: Lee SK). Pediatric Academic Societies Travel Award.

Lee SK. Magnolia Silver Award, Shanghai Government.

Lee SK. President’s Lecture, Canadian Paediatric Society Annual Meeting in London.

Lee SK. Researcher of Month (February), Canadians for Health Research.

Lee SK. Visiting Professorship, Medical University of South Carolina, Charleston, SC.

Lee SK. Visiting Professorship, Qizhou Maternity Hospital, Jinan, People’s Republic of China.

Leibel S. Outstanding Fellow Teaching Award, Pediatric Residents of St. Louis Children’s Hospital.

Leibel S. SPR Travel Award, Pediatric Academic Society.

Morais M (supervisor: Shah P). Best Poster Presentation, Annual Research Day of Department of Obstetrics and Gynecology, University of Toronto.

O’Brien K. Karen McGibbon Award for Innovation, Mount Sinai Hospital.

Panczuk J (supervisor: Unger S). Postgraduate Medical Research Award, University of Toronto.

Shah P. Emerging Leader in Neonatology Award from the Canadian Pediatric Society.

Shah P. Karen McGibbon Award of Excellence for Inter-professional Team Participation by the Improving Quality Team (Co-Leader), Mount Sinai Hospital.

Shah V. Canadian Pain Society’s Pain Awareness Award for HELPinKIDS website and video.

Francis J (supervisor: Unger S). SickKids Hospital Foundation Trainee Support, Hospital for Sick Children.

2011Almidani E (supervisor: Shah V). Best Poster, 10th Annual Neonatal-Perinatal Research Day, University of Toronto.

Azarpazooh A (supervisor: Shah P). Cochrane Canada Review of the Year Award, Cochrane Collaboration.

El-Khuffash A. Project winner in the fellows section of the 23rd Canadian Fellows and Residents research competition: Use of Early Targeted Neonatal Echocardiography (TnECHO) to Predict and Prevent Postoperative Cardio-Respiratory Instability Following PDA Ligation.

Infantino J (supervisor: Shah P). Best Scientific Research Presentation Award, Annual Canadian Respirology Conference.

Jain A. Exceptional Trainee Award, Physiology & Experimental Medicine Program, The Hospital for Sick Children Research Institute.

Jain A. Selected to represent the Department of Paediatrics, University of Toronto at 23rd Annual Canadian Pediatric Fellow Research Competition, Manitoba Institute of Child Health.

Jain A. Winner of the 23rd Annual Canadian Pediatric Fellow Research Competition, Manitoba Institute of Child Health.

Ko G (supervisor: Lee SK). Pediatrics Academic Societies Summer Studentship Award.

Luk Y (supervisor: Unger S). SickKids Hospital Foundation Trainee Support, Hospital for Sick Children.

Mohamed A. Selected for Oral Presentation, 19th Western Perinatal Research Meeting in Banff.

Shah P. Physician Researcher Award for Scientific Accomplishment, Department of Paediatrics, University of Toronto.

Shah P. Teaching Excellence Award for the Neonatal-Perinatal Medicine Fellowship Training Program, University of Toronto.

Shah V. Canadian Society for Pharmacology & Therapeutics Publication Award for article “Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline” (CMAJ 2010;182:E843-55).

Zhao M (supervisor: Shah P). Best Oral Presentation Award, Annual Research Day, Department of Obstetrics and Gynecology, University of Toronto.

2010Bassil K. Dr. Susan J. Ditchburn Young Alumna Award Distinction, Havergal College.

Boyajian T (supervisor: Shah P). Best Presentation (Health Services Research) Award/HPME Student Union Poster Award - Best MSc Poster, University of Toronto.

Brennan-Donnan J (supervisor: Unger S). Restacom Research Fellowship, The Hospital for Sick Children.

5710-Year Report

El-Khuffash A. Winner of Best Neonatal Platform Presentation, 9th Annual Neonatal and Maternal - Fetal Medicine Research Day, Toronto.

El-Khuffash A (PI). PAS Young Investigator’s Travel Award.

Hui D (supervisor: Shah P). Best Poster Presentation Award, Annual Research Day, Department of Obstetrics and Gynecology, University of Toronto.

Jain A. Selected to present at Mid-Atlantic Conference on Perinatal Research, Hershey, PA.

Jefferies A. Excellence in Teaching Award, Neonatal–Perinatal Medicine Fellowship Training Program, University of Toronto.

Jefferies A. Nominated for Subspecialty Teaching Award, Department of Paediatrics, University of Toronto.

Jefferies A. Patil award for platform presentation in the area of Teaching and Learning. Association for Medical Education in Europe Annual Conference.

Ko G (supervisor: Lee SK). Hospital for Sick Children Research Institute Summer Studentship Award.

Lee SK. Ontario Health Innovation Merit Award, 2010 Innovations in Health Care Expo, Toronto.

Mirea L. Best Trainee Oral Presentation – Distinction, 5th Annual Canadian Genetic Epidemiology and Statistical Genetics Meeting.

Mohamed A. Selected for Oral Presentation, 33rd Mid-Atlantic Conference on Perinatal Research in Pennsylvania.

Shah P. Glory of India Award and Certificate of Excellence from India International Friendship Society.

Shah P. Teaching Excellence Award for the Neonatal-Perinatal Medicine Fellowship Training Program (selected by trainees as Nominee for Teacher of the Year), University of Toronto.

Shah V. Association for Medical Education in Europe Patil Award for presentation in the area of Teaching and Learning.

Shah V. The Karen McGibbon Award of Excellence/Seymor Schulich Honorarium Awarded for Excellence in Innovation.

Williams C. Douglas Kinsella Doctoral Award for Research in Bioethics (awarded to the highest ranked and funded applicant conducting research in bioethics in the 2010 CIHR Doctoral Research Award competition), Canadian Institutes of Health Research.

Williams C. Research Doctoral Award – Frederick Banting and Charles Best Canada Graduate Scholarship, Canadian Institutes of Health Research.

Zao J (supervisor: Shah P). Best Poster Presentation Award, 9th Annual Neonatal-Perinatal and Maternal Fetal Medicine Research Day, University of Toronto.

2009El Sayed M (supervisor: Shah P). Best Oral Presentation Award, 8th Annual Neonatal-Perinatal and Maternal Fetal Medicine Research Day, University of Toronto.

Lee SK. Women’s Auxiliary Chair in Neonatology, The Hospital for Sick Children (2009–2012).

Lee SK. Visiting Professorship, Gansu Provincial Maternity Hospital, Lanzhou, People’s Republic of China.

Mirea L. Sellers Travel Award, Cancer Care Ontario.

Qiu X (supervisor: Lee SK). Fred & Jane Bryans Trainee Presentation Award, 17th Annual Western Perinatal Research Meeting.

Shah P. Teaching Excellence Award for the Neonatal-Perinatal Medicine Fellowship Training Program, University of Toronto.

Unger S. Woman of Distinction Award, Honoree, Mount Sinai Hospital.

Williams C. JKR Wightman Scholarship in Ethics for paper entitled: “Shared Decision Making in the NICU: the Virtuous Triad”, Royal College of Physicians and Surgeons.

Williams C. Best oral presentation, Health Policy Management and Evaluation Research Day.

Yao S (supervisor Lee SK). Hospital for Sick Children Research Institute Summer Studentship.


2018Unger S (PI). Ontario Human Milk Bank. Ontario Ministry of Health and Long-Term Care $444,000; 2018.

Shah P (Co-I). Quality of Life of Patients with Medication-Related Osteonecrosis of the Jaw (MRONJ): A Prospective Cohort Study. Canadian Association of Oral and Maxillofacial Surgeons $9,600; 2018-2019.

Hopperton K (PI), Unger S (Co-PI). CIHR Doctoral Award. Canadian Institutes of Health Research $135,000; 2018-2021.

2017Jain A (PI), Shah P (Sup). Early identification of preterm neonates with evolving chronic pulmonary hypertension: utility of functional echocardiographic markers. Canadian Institutes of Health Research-SickKids Foundation $296,000; 2017-2020.

Jain A (PI). 1st Clinical Cardiopulmonary Physiology for the Care of the Sick Newborn. Mallinckrodt Young Investigator Fund $10,000; 2017.

Lee SK (PI). MiCare’s Clinician-Scientists Training Program. Ontario Ministry of Health & Long-Term Care $1,300,000; 2016-2017.

Lee SK (PI), Shah P (Co-I), Jain (Co-I). Toronto Perinatal Brain Protection Research Collaboration. Canadian Foundation for Innovation $2,343,263; 2017-2021.

O’Brien K (PI). Family Integrated Care in the neonatal intensive care unit and child behavior at 18 months: hair cortisol and DHEA assay. Physicians Services Incorporated $31,497; 2017.

O’Brien K (PI). A pilot study of Family Integrated Care (FICare) in critically ill and ventilated preterm infants in the NICU: FICarePlus. AHSC AFP Innovation Fund $95,718; 2017-2019.

Shah P (Co-I). Comparative efficacy of parent-focused interventions and sweet tasting solutions for procedural pain in neonates: A systematic review and Network meta-analyses. Canadian Institutes of Health Research $90,000; 2017-2018.

Shah P (Co-I). Comparative efficacy of parent-focused interventions and sweet tasting solutions for procedural pain in neonates: A systematic review and Network meta-analyses. Nova Scotia Health Services Research Fund $100,000; 2017-2018.

Shah P (Co-I). TRajectories Of healthy life using Public Health and primary care Interventions in Canada: The TROPHIC Trial. Canadian Institutes of Health Research $17,050,000; 2017-2026.

Shah P (Co-Sup). Ontario Graduate Scholarship from Ontario Ministry of Advanced Education and Skills Development. Ontario Graduate Scholarship $15,000; 2017-2018.

Shah P (Co-I). Non-Invasive Respiratory Support in Preterm Infants: A Pilot Randomized Controlled Trial. Hamilton Health Sciences New Investigator Fund $49,841; 2017-2019.

Shah P (Co-PI). Early INtervention to Support Healthy Life TrajectoriEs in INdia (EINSTEIN). Canadian Institutes of Health Research-India Partnership $5,000,000; 2017-2026

Shah P (Co-I). An electronic medical record best practice alert of progesterone to prevent preterm birth: A pragmatic pilot cluster randomized controlled trial. Canadian Institutes of Health Research $99,984; 2017-2018.

Shah P (PI). A systems approach for enhancing perinatal care regionalization. Canadian Institutes of Health Research $1,000,000; 2017-2021.

FUNDING

5910-Year Report

Shah P (PI), Shah V (Co-I), O’Brien K (Co-I). Improving outcomes of preterm infants and their families: A collaborative Canadian Network. Canadian Institutes of Health Research $4,250,000; 2017-2021.

Shah P (Co-PI). Early INtervention to Support Healthy Life TrajectoriEs in INdia (EINSTEIN). Canadian Institutes of Health Research-India Partnership (NOI) $30,000; 2017.

Shah V (Co-I). Family Integrated Care (FICare) for Medically Fragile Infants on Paediatric Inpatients Units: A Feasibility and Modified Pilot Study. Alberta Children’s Hospital Research Institute $225,000; 2017-2020.

Shah V (Co-I). A Prospective Multi Centre Investigation of the Efficacy of the Draeger Jaundice Meter (JM-105) in Providing Transcutaneous Bilirubin Measurements to Compare Serum Total Bilirubin in Neonates of ≥24Weeks of Gestational Age or Older Who Have and Have Not Undergone Phototherapy. Draeger Medical Systems Inc $150,000; 2017-2018.

Unger S (PI), O’Connor (Co-I). Bacillus cereus contamination of human milk banks: Whole-genome sequencing to the rescue. McLaughlin Centre Accelerator Grant, University of Toronto $100,000; 2017.

Unger S (Co-I). Restacom Research Fellowship Grant. The Hospital for Sick Children $78,000; 2017-2020.

Unger S (PI). Ontario Human Milk Bank. Ontario Ministry of Health and Long Term Care $167,000; 2017.

2016Finan E (Co-I). Development and Validation of a Competency Assessment Tool for Bag Mask Ventilation. American Academy of Pediatrics, Neonatal Resuscitation Program $15,000; 2016.

Kelly E (Co-I). Brain development following late onset intrauterine growth restriction. Canadian Institutes of Health Research $550,440; 2016-2019.

Lee SK (PI). Institute of Human Development, Child & Youth Health Support Grant. Canadian Institutes of Health Research $4,000,000; 2016-2020.

Lee SK (PI). Research Development Grant. Canadian Institutes Health Research $750,000; 2016-2020.

Shah P (Co-PI), El-Rabbany M (PI). A Critical Evaluation of the Therapeutic Efficacies of Current Medication- Related Osteonecrosis of the Jaw (MRONJ) Management Strategies: A Retrospective Cohort Study. The Canadian Association of Oral and Maxillofacial Surgeons $2,500; 2016-2017.

Shah P (Co-I). Necrotizing Enterocolitis Research Program: introducing innovative therapies to halt the disease progression and promote recovery. CIHR Foundation Grant $3,700,000; 2016-2022.

Shah P (Co-I). Laparoscopic versus open resection for the surgical management of rectal cancer. Canadian Institutes of Health Research $90,000; 2016-2017.

Shah P (Co-Sup), El-Rabbany (PI). Dr. Barry Korzen Scholarship. University of Toronto $4,618.44; 2016-2017.

Shah P (Co-Sup), El-Rabbany (PI). Herron Scholarships. University of Toronto $5,873.25; 2016-2017.

Shah P (Co-Sup), El-Rabbany (PI). Ontario Graduate Scholarship. Ontario Ministry of Advanced Education and Skills Development $15,000; 2016-2017.

Shah P (Co-Sup), El-Rabbany (PI). Ontario Graduate Scholarship. Ontario Ministry of Advanced Education and Skills Development $30,000; 2016-2017.

Shah P (Sup), Beltempo M (PI). Training Grants Program in Post-Diploma Research. Fonds de Recherche Sante Quebec $78,646; 2016-2018.

Shah P (Co-I). Child Bright-SPOR Network. Canadian Institutes of Health Research $25,000,000;

2016-2022.

Shah P (Co-I). Primary Prevention of Preterm Birth: a Systematic Review and Network Meta-Analysis. Canadian Institutes of Health Research $100,000; 2016-2017.

Shah P (Co-I). Regional and temporal variations in incidence, prevalence and outcomes of critical illness among pregnant and post-partum women and newborns in Canada. Canadian Institutes of Health Research $46,415; 2016-2018.

Shah V (PI). Pain management from skin-breaking procedures in neonates: Knowledge synthesis and practice guidelines. Canadian Institutes of Health Research $100,000; 2016-2017.

Shah V (Co-I). Child developmental health, maternal psychosocial distress, and health costs at 18 months corrected age: Effectiveness of a cluster randomized controlled trial of Family Integrated Care (FICare) in Level II NICUs. Canadian Institutes of Health Research $199,812; 2016-2018.

2015Finan E (Co-I), Jefferies A (Collaborator). Development and Validation of a Neonatal Intubation Competency Assessment Tool. Neonatal Resuscitation Program, Canadian Paediatric Society $25,000; 2015.

Jain A (PI). Validation of echocardiographic indices of right ventricular function by comparison with cardiac MRI for preterm infants with moderate to severe BPD. Mallinckrodt Young Investigator Fund and Forum $20,000; 2015.

Kelly E (Co-PI). Preterm care MRI study: Analgesia and Sedation in the Preterm Neonate. Canadian Institutes of Health Research $1,104,217; 2015-2021.

Lee SK (PI). Maternal-Infant Care Research Centre Clinician-Scientist Training Program. Ministry of Health and Long-Term Care $1,500,000;


2015-2016.

Lee SK (PI). CIHR Team in Maternal-Infant Care Research. Canadian Institutes of Health Research $8,895,019; 2015-2021.

O’Brien (PI), Mirea L (Co-I). Association of parent-infant interaction and chronic stress at 8 and 18 months of age with child behavior following Family Integrated Care (FICare) in the neonatal intensive care unit. Canadian Institutes of Health Research $201,000; 2015-2017.

Shah P (Co-PI), Tuerxun R (Co-PI). Utility of Procalcitonin and C reactive protein in Late-Onset Neonatal Sepsis. China-Canada Clinical Research Program RMB60,000; 2015-2018.

Shah P (Co-I), Kingdom J (PI). Placental health predictors of brain development and cognitive outcomes in early childhood. J P Bicknell Foundation $65,000; 2015-2017.

Shah P (PI). Meeting Grant: Annual Neonatal-Perinatal Medicine Research Day. Ikaria Educational Fund $5,000; 2015.

Shah P (Co-PI). Oral paracetamol for the treatment of patent ductus arteriosus in very low birth weight infants: Neurodevelopmental outcomes in early childhood. China-Canada Clinical Research Program RMB60,000; 2014-2017.

Shah P (Co-I). Efficacy and Safety of Preventions for Preterm Birth: A Systematic Review and Network Meta-Analysis. Canadian Institutes of Health Research $100,000; 2015-2016.

Shah V (Co-I). Family Integrated Care (FICare) in Level II NICUs – Planning and Communications: Workshop. Alberta Innovates Health Solutions $6,000; 2015.

Shah V (Co-PI). Reduction of infection in neonatal intensive care units using the Evidence-based Practice for Improving Quality (REIN-EPIQ). China Medical Board $202,500; 2015-2019.

Shah V (Co-PI). Family Integrated Care (FICare) in Level II NICUs: An Innovative Program in Alberta. Alberta Innovates Health Solutions $750,000; 2015-2017.

Unger S (PI), O’Connor D (PI), Shah P (Co-I). Maximizing Mothers’ Milk for Preterm Infants (MaxiMoM). Canadian Institutes of Health Research $2,838,256; 2015-2021.

Unger S (PI). Ontario Human Milk Bank. The Rotman Family Foundation $100,000; 2015-2016.

2014Finan E (Co-I). Simulation based team leadership training for neonatal resuscitation: is learning by observation as effective as learning by participation? Neonatal Resuscitation Program, Canadian Paediatric Society $5,000; 2014.

Kelly E (Co-PI). Origins of Cerebral Palsy: Genes and Brain Development. Ontario Brain Institute and The Hospital for Sick Children $453,100; 2014-2018.

Kelly E (Co-I). Fetal Atrial Flutter & Supraventricular Tachycardia (FAST) Therapy Trial: Proposal of an International Registry and Randomized Controlled Trial (RCT). Canadian Institutes of Health Research-The Hospital for Sick Children $1,079,804; 2014-2018

Lee SK (Co-I). Family Integrated Care in China. China Medical Foundation $135,000; 2014-2017.

Lee SK (Co-I), Shah V (Co-I). EPIQ in China. China Medical Foundation $135,000; 2014-2017.

Lee SK (Co-I). A quality improvement initiative to increase breast milk feeding in a Chinese hospital: a pilot study. Medela Corporation RMB250,000; 2014-2016.

Mirea L (Co-I). Effect of dietary flaxseed on circulating sex hormone levels among post-menopausal women – an intervention trial to explore flaxseed intake as a possible breast cancer prevention strategy. Canadian Breast Cancer

Foundation $449,118; 2014-2017.


Shah P (PI). Outcomes of infants born between 31 and 32 weeks GA based on location of birth in Ontario. Provincial Council on Maternal and Child Health $135,000; 2013-2016.

Shah V (Co-I). Assessment of the Quality of General Movements for identification of long-term neurodevelopmental outcome in preterm infants. Physicians Services Incorporated $37,500; 2014-2015.

Unger S (PI). Ontario Human Milk Bank. Rogers Foundation $471,000; 2014-2019.

Unger S (PI), O’Connor D (PI), Shah P (Co-I). Impact of Feeding Type and Nutrient Fortification on the Gut Microbiome of Very Low Birth Weight Infants. Canadian Institutes of Health Research $633,157; 2013-2015.

2013Finan E (PI), Jefferies A (Co-I). Is simulation an effective way to teach communication skills? Paediatric Consultant’s Educational Research Grant $3,822; 2013.

Jain A (PI). Four year salary in support of PhD related research work (Doctoral Award). SickKids Clinician-Scientist Training Program $200,000; 2013-2017.

Lee KS (PI), Shah P (PI), Lee S (Co-I), Mirea L (Co-I). Improving quality of care during transport of sick neonates: A national collaborative partnership for outcome improvement and system enhancement. Canadian Institutes of Health Research $524,643; 2013-2016.

Mirea L (Co-I). Evaluating the effectiveness of organized breast assessment among women screened in the Ontario Breast Screening Program. Canadian Institutes of Health Research $463,733; 2013–2016.

6110-Year Report

Mukerji A (PI), Shah V (supervisor). A randomized controlled trial of biphasic nasal continuous positive airway pressure versus non-invasive high frequency ventilation (NIHFV) post NCPAP failure: A pilot study. Sandra Schmirler Foundation Fellowship $10,000; 2013.

Shah P (Co-I). Determinants of late preterm birth. Physician Services Incorporation Foundation $77,500; 2013-2015.

Shah P (Co-I). Spatial data mining exploring co-location of adverse birth outcomes and environmental variables. Canadian Institutes of Health Research $801,858; 2013-2016.

Shah P (PI). Meeting Grant: First Canadian Neonatal Trainees’ Research Day. Ikaria Educational Fund $5,000; 2013.

Shah P (PI). Canada Applied Research Chair in Maternal and Child Health Services Research. Canadian Institutes of Health Research $925,000; 2013-2017.

Shah V (Co-I). Needle fears in children undergoing medical procedures: Knowledge synthesis, practice guidelines, and dissemination strategies. Canadian Institutes of Health Research $99,936; 2013–2014.

Shah V (Co-I). A hospital-based postnatal parent education program for evidence-based pain management during infant immunization injections. Canadian Institutes of Health Research $439,777; 2013.

Shah V (PI), Lee S (Co-I). Family Integrated Care - development and introduction in Level 2 hospitals. Canadian Institutes of Health Research $200,000; 2013-2015.

Shah V (PI), O’Brien K (Co-I). Adaptation and implementation of an innovative program of family integrated care (FICare) in Level II NICUs in Ontario. Academic Health Science Centres Academic Funding Plan $199,548; 2013-2015.

Unger S (PI), Shah P (Collaborator). OPTIMoM: Optimizing PreTerm Infant Mothers’ Milk. Canadian Institutes of Health Research $2,000,000; 2013-2018.

Unger S (Co-PI). Impact of feeding type and nutrient fortification on the gut microbiome of very low birth weight infants. Canadian Institutes of Health Research $377,154; 2013-2016.

Unger S (PI). Impact of feeding type and nutrient fortification on the gut microbiome of very low birth weight infants. Physicians Services Incorporated $170,000; 2013-2015.

2012Bassil K (Co-I). Knowledge translation tools for capacity-building in Canadian Environmental Health Atlas. Canadian Institutes of Health Research $98,974; 2012-2013.

El-Khuffash A (PI). Establishing reference ranges of myocardial function in preterm infants using tissue Doppler Imaging and Speckle Tracking techniques. William S. Fenwick Award and the Edie Steinberg Scholarship Fund $9,900; 2012.

Feig D (PI), Lee S (Co-I). MiTy Kids (Metformin in Women with Type 2 Diabetes in Pregnancy Kids Trial). Canadian Institutes of Health Research $1,299,072; 2012-2018.

Jain A (PI). Graduate Scholarship in Science and Technology. Queen Elizabeth II/Heart & Stroke Foundation of Ontario $15,000; 2012-2013.

Lee SK (PA), O’Brien K (PI). A Family integrated care model for the neonatal intensive care unit. Canadian Institutes of Health Research $349,982; 2012-2014.

Lee SK (PI), Shah P (Co-I). Provincial level 2 database. Ontario Ministry of Health and Long-Term Care $200,000; 2012-2013.

Lee SK (PI). EPIQ II - Improving quality of care in the NICU. Canadian Institutes of Health Research $4,000,000; 2012-2015.

Lee SK (PI). IHDCYH Institute Support Grant. Canadian Institutes of Health Research $4,000,000; 2012-2015.

Lee SK (PI). Research Development Grant. Canadian Institutes of Health Research $600,000; 2012-2015.

O’Brien K (PI). Support of an RSVP data-management system. Abbvie Canada Corporation $180,000; 2012-2014.

Shah P (Co-PI). Meeting Grant: Annual Neonatal-Perinatal Medicine Research Day. Ikaria Educational Fund $5,000; 2012.

Shah P (PI). Outcomes of infants born between 31 and 32 weeks GA based on location of birth in Ontario. Provincial Council on Maternal and Child Health $135,000; 2012-2015.

Shah V (Co-I). A RCT to evaluate the impact of a Fact sheet about childhood immunization pain management on parental knowledge. Paediatric Consultants Grant $5,000; 2012.

Shah V (Supervisor). Effect of maternal skin-to-skin contact (SSC) in the delivery room on the skin colonization of Preterm infants: A pilot randomized controlled study. Physicians Services Incorporation $11,850; 2012.

2011Bassil K (Co-I). Canadian Pediatric Surgery Network (CAPSNet). Canadian Institutes of Health Research $100,000; 2011-2013.

Bassil K (PI). Improving health of late preterm infants: Developing a Canadian research agenda $9,845; 2011-2012.

Bassil K (Co-I). Knowledge translation and exchange for dissemination of the Canadian Environmental Health Atlas. Canadian Institutes of Health Research $24,890; 2011-2012.

Church P (PI), Lee S (Co-I), Bassil K (Co-I), Shah V (Co-PI). Academic challenges for the preterm infant: Educators’ knowledge, attitudes,


and identified barriers to providing aid to this population. Physicians Services Incorporation $61,000; 2011-2012.

El-Khuffash A (PI). Targeted Neonatal Echocardiography teaching application for smart phones and tablet PCs. Ikaria Educational Grant $35,000; 2011.

El-Khuffash A (PI), Jain A (Co-I). The use of NICOM in assessing the hemodynamic state of premature infants. The Hospital for Sick Children Research Start-Up Grant Award $3,000; 2011.

Kourosh S (PI), Lee S (Co-I). The first national retinopathy of prematurity survey: Formulating evidence-based screening recommendations. Canadian Institutes of Health Research $349,982; 2011-2014.

Lee SK (PI), Shah V (Co-I). GentleR Study: a cluster randomized controlled trial. AHSC AFP Innovation Fund $200,000; 2011-2013.

Lee SK (PI). Creating an innovative problem oriented documentation system to enhance clinical documentation for level 3 NICUs. AHSC Innovation Fund $200,000; 2011-2013.

Magee L (PI), Lee S (Co-I). CHIPS-Child: Testing the development origins hypothesis. Canadian Institutes of Health Research $1,190,436; 2011-2015.

Offringa M (Co-I). Global Research in Pediatrics: GRiP Network of Excellence. European Union (EU) Research Directorate General 700,000 (Euro); 2011-2015.

Shah P (Co-I). Delayed cord clamping in preterm infants: a randomized controlled trial. Department of Obstetrics and Gynecology Research Fund $4,000; 2011-2012.

Shah P (Co-I). Maternal hemodynamic changes in multiple gestation pregnancy. Department of Obstetrics and Gynecology Research Fund $20,000; 2011-2012.

Shah P (Co-PI). Knowledge Synthesis Grant: “What is the impact of Early Childhood Education and Care (ECEC) program quality on children’s developmental health?” Canadian Institutes of Health Research $56,040; 2011-2012.

Shah P (PI). Meeting Grant: Annual Neonatal-Perinatal Medicine Research Day. Ikaria Educational Fund $5,000. 2011.

Shah V (Co-I). Can we change the face of immunization to one without pain? Implementation of a postnatal parental education intervention to optimize pain management during childhood immunization. Canadian Institutes of Health Research $100,000; 2011.

Shah V (Co-I). Severe neonatal hyperbilirubinemia after implementation of the Canadian Paediatric Society Guideline (2007). Public Health Agency of Canada $40,000; 2011.

Shah V (PI), Jain A (Co-I). Comparison of 2% chlorhexidine in 70% isopropyl alcohol versus 2% aqueous chlorhexidine for skin antisepsis prior to venepuncture in very low birth weight infants: A planned non-inferiority trial. Physicians Services Incorporation $136,000; 2011.

Stevens B (PI), Lee S (Co-I). Sustainability of a multidimensional knowledge translation intervention to improve paediatric pain practices and outcomes. Canadian Institutes of Health Research $822,401; 2011-2015.

Von Dadelszen P (PI), Lee S (Co-I). Clinical prediction models for critically ill pregnant women: MEOWS and CIPHER. Canadian Institutes of Health Research $100,000; 2011-2012

2010El-Khuffash A (PI), Jain A (Co-I). The use of echocardiographic and biochemical markers to predict low cardiac output following patent ductus arteriosus ligation in preterm infants. The Physicians’ Services Incorporated Foundation $15,900; 2010.

Finan E (PI). A comparison of debriefing methods following simulated neonatal resusciation. NRP Research Grant $16,180; 2010.

Jain A (Co-I). The use of echocardiographic and biochemical markers to predict low cardiac output following patent ductus arteriosus ligation in preterm infants. Physicians’ Services Incorporated Foundation $15,900; 2010.

Jain A (Co-PI). Double blinded randomized controlled non inferiority trial comparing skin cleansing efficacy of 2% chlorhexidine in 70% alcohol to 2% aqueous chlorhexidine for skin antisepsis in VLBW infants prior to venepuncture. Physicians’ Services Incorporated Foundation $136,000; 2010.

Jefferies A (PI), Finan E (Co-I). A CIPP framework for implementation and evaluation of a faculty development program for Neonatal–Perinatal Medicine. University of Toronto Continuing Education Research and Development Grant $4,900; 2010-2011.

Lee SK (PI). Provincial Infection Control Group. Ontario Ministry of Health and Long-Term Care $150,000; 2010–2011.

McGregor C (PI), Lee S (Co-I). CIHR Team in Neonatal Clinical Decision Support. Canadian Institutes of Health Research $150,000; 2010-2013.

O’Brien K (PI). Development of an RSVP data-management system. Abbott Laboratories Limited $120,000; 2010-2011.

Offringa M (PI). Moderately early hydrocortisone for ventilated preterm infants at risk for bronchopulmonary dysplasia: A multicenter randomized placebo controlled trial: STOP-BPD. The Netherlands Organization for Health Research and Development ZonMW-Priority Medicines 600,000 (Euro); 2010-2014.

Offringa M (PI). Pharmacokinetics and Pharmacodynamics of Medication in Asphyxiated

6310-Year Report

Newborns During Controlled Hypothermia - PharmaCool National Multicenter Study. The Netherlands Organization for Health Research and Development ZonMW-Priority Medicines 600,000 (Euro); 2010-2014.

Offringa M (Co-I). Development and use of a standardized instrument for assessing children’s competence to consent in drug trials: are legally established age limits valid? The Netherlands Organization for Health Research and Development ZonMW 400,000 (Euro); 2010-2014.

Shah P (Co-I). Meeting Planning and Dissemination Grant: Late preterm births. Canadian Institutes of Health Research $10,000; 2011.


Shah V (Co-I). Reducing the pain of childhood immunization: An evidence-based clinical practice guideline. Canadian Pain Society $10,000; 2010.

Shah V (PI). Healthcare Professionals Perceptions and Learning Experience about GentleR Pilot Clinical Trial. Ikaria $31,000; 2010.

Shah V (PI). Reducing the pain of childhood immunization: An evidence-based clinical practice guideline. Linden Fund $10,000; 2010.

Shah V (Co-I). Reducing the pain of childhood immunization: An evidence-based clinical practice guideline. Canadian Pain Society $10,000; 2010.

Skarsgard E (PI), Lee S (Co-I). The Canadian Pediatric Surgery Network (CAPSNet): Establishing best practices for gastroschisis and diaphragmatic hernia. Canadian Institutes of Health Research $100,000; 2010-2011.

Unger S (PI). DoMINO: Donor Milk for Improved Neurodevelopmental Outcomes. Canadian Institutes for Health Research $920,270; 2010-2015

2009Bassil K (PI). Development and dissemination of a Canadian Environmental Health Atlas. Canadian Institutes of Health Research $94,800; 2009-2011.

Fassbender D (PI), Lee S (Co-I). The Economics of Palliative and End of Life Care: An examination of the costs and consequences of caring for terminally ill cancer patients. Canadian Institutes of Health Research $45,500; 2009.

Jefferies A (PI). A multi-faceted approach to the implementation of recommendations for management of infants at increased risk for sepsis for the interprofessional health care team. Academic Health Sciences Alternate Funding Plan Phase III Innovation Fund $39,613; 2009-2010.

Jefferies A (Co-I). Resuscitation competencies in inter-professional education. Neonatal Resuscitation Program Research Grant $17,590; 2009-2010.

Jefferies A (PI). Improving safety in the insertion and care of percutaneously inserted central catheters (PICCs) and umbilical catheters (UCs) in 3 neonatal intensive care units (NICUs). CMPA Collaborative Research Grant $49,750; 2009-2010.

Lee SK (PI). Maternal-Infant Care (MiCare) Research Centre. Ontario Ministry of Health and Long-Term Care $15,000,000; 2009-2013.

Lee SK (PI). The Women’s Auxiliary Chair in Neonatology. The Hospital for Sick Children $350,000; 2009-2013.

Puligandla P (PI), Lee S (Co-I). Canadian Pediatric Surgery Network Extension (CAPSNet-X). Canadian Institutes of Health Research $10,000; 2009-2010.

Rieger J (PI), Lee S (Co-I). Head and Neck Research Network: a multidisciplinary Canadian-based international team for improving communication and quality of life in head and neck cancer survivors. Canadian Institutes of Health Research $4,923; 2009-2010.


Shah V (Co-I). Meetings, Planning and Dissemination Grant: Knowledge Translation Supplement. Canadian Institutes of Health Research $38,788; 2009.

Shah V (PI). Innovation Fund Project: An innovative Multi-faceted approach to Implementation of recommendations for management of infants at increased risk for sepsis for inter-professional health care team. Ministry of Health and Long-Term Care $41,850; 2009.

Unger S (PI), O’Brien K (Co-I). Implementation of a wireless patient identification system for the prevention of breast milk errors in the NICU. Ontario Ministry of Health and Long-Term Care $56,807; 2009-2012.

Unger S (PI), O’Brien K (Co-PI). Implementation of a Wireless Positive Patient Identification System for the Prevention of Breastmilk Errors in the NICU. Ministry of Health of Ontario Academic Health Sciences Centre Innovation Fund $60,014; 2009-2013.

Wen S (PI), Lee S (Co-I). Effect of folic acid supplementation in pregnancy on preeclampsia. Canadian Institutes of Health Research $6,448,423; 2009-2014.


PUBLICATIONS2018Acuna SA, Chesney TR, Ramjist JK, Shah PS, Kennedy ED, Baxter NN. Laparoscopic Versus Open Resection for Rectal Cancer: A Noninferiority Meta-analysis of Quality of Surgical Resection Outcomes. Ann Surg. 2018 Oct 17. doi: 10.1097/SLA.0000000000003072. [Epub ahead of print]

Amer R, Moddemann D, Seshia M, Alvaro R, Synnes A, Lee KS, Lee SK, Shah PS, Canadian Neonatal Network and Canadian Neonatal Follow-up Network Investigators. Neurodevelopmental outcomes of preterm infants <29 weeks gestation based on location of birth in Canada. J Pediatr. 2018 May;196:31-37.e1.

Anderson LN, Knight JA, Hung RJ, Hewko SL, Seeto RA, Martin MJ, Fleming A, Maguire JL, Matthews SG, Murphy KE, Okun N, Jenkins JM, Lye SJ, Bocking A. Ontario Birth Study Collaboration (Shah PS). The Ontario Birth Study: A prospective pregnancy cohort study integrating perinatal research into clinical care. Paediatr Perinat Epidemiol. 2018 May;32(3):290-301.

Aoyama K, D’Souza R, Pinto R, Ray JG, Hill A, Scales DC, Lapinsky SE, Seaward GR, Hladunewich M, Shah PS, Fowler RA. Risk prediction models for maternal mortality: A systematic review and meta-analysis. PLoS One. 2018 Dec 4;13(12):e0208563.

Auger N, Bilodeau-Bertrand M, Poissant J, Shah PS. Decreasing use of autopsy for stillbirths and infant deaths: missed opportunity. J Perinatol. 2018 Oct;38(10):1414-1419.

Baczynski M, Ginty S, Weisz D, McNamara P, Kelly E, Shah P, Jain A. Outcomes of hypoxic respiratory failure at birth associated with

previable rupture of membranes. J Perinatol. 2018 Aug;38(8):1087-1092.

Beltempo M, Isayama T, Vento M, Lui K, Kusuda S, Lehtonen L, Sjörs G, Håkannson S, Adams M, Noguchi A, Reichman B, Darlow BA, Morisaki N, Bassler D, Rusconi F, Lee S, Lodha A, Modi N, Helenius K, Shah PS on behalf of the International Network for Evaluating Outcomes of Neonates. Respiratory management of extremely preterm infants: an international survey. Neonatology 2018 Apr 13;114(1):28-36.

Beltempo M, Lee SK, McMillan DD, Afifi J, Ye P, Shah P, Canadian Neonatal Network. SNAP-II for prediction of mortality and morbidity in extremely preterm infants. J Matern Fetal Neonatal Med. 2018 Mar;12:1-8.

Benzies KM, Shah V, Aziz K, Lodha A, Misfeldt R. The health care system is making ‘too much noise’ to provide family-centered care in neonatal intensive care units: Perspectives of health care providers and hospital administrators. Intensive Crit Care Nurs. 2019 Feb;50:44-53.

Bhide A, Shah PS, Acharya G. A simplified guide to randomized controlled trials. Acta Obstet Gynecol Scand. 2018 Apr;97(4):380-387.

Butcher J, Unger S, Li J, Brando N, Romain G, Francis J, Mottawea W, Mack D, Stinzi A, O’Connor DL. Independent of birth mode or gestational age, very low birth-weight infants fed mother’s milk rapidly develop personalized microbiotas low in Bifidobacterium. J Nutr. 2018 Mar 1;148(3):326-335.

Castro M, Asbury M, Shama S, Stone D, Yoon EW, O’Connor DL, Unger S. Energy and Fat Intake for Preterm Infants Fed Donor Milk Is Significantly Impacted by Enteral

Feeding Method. JPEN J Parenter Enteral Nutr. 2019 Jan;43;162-165.

Church PT, Cavanagh A, Lee SK, Shah V. Academic challenges for the preterm infant: Parent and educators’ perspectives. Early Hum Dev. 2019 Jan;128:1-5.

Costeloe K, Turner MA, Padula MA, Shah PS, Modi N, Soll R, Haumont D, Kusuda S, Göpel W, Chang YS, Smith PB, Lui K, Davis JM, Hudson LD; International Neonatal Consortium. Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions. J Pediatr. 2018 Dec;203:437-441.e1.

D’Souza R, Shah PS, Sander B.Clinical decision analysis in perinatology. Acta Obstet Gynecol Scand. 2018 Apr;97(4):491-499.

de Freitas Martins F, Ibarra Rios D, F Resende MH, Javed H, Weisz D, Jain A, de Andrade Lopes JM, McNamara PJ. Relationship of Patent Ductus Arteriosus Size to Echocardiographic Markers of Shunt Volume. J Pediatr. 2018 Nov;202:50-55.e3.

Darlow BA, Vento M, Beltempo M, Lehtonen L, Håkansson S, Reichman B, Helenius K, Norman M, Rusconi F, Lee S, Noguchi A, Morisaki N, Kusuda S, Bassler D, San Feliciano L, Adams M, Isayama T, Lui K, Shah PS, International Network for Evaluating Outcomes (iNeo) of Neonates. Variation in oxygen saturation targeting, retinopathy of prematurity screening and treatment criteria amongst neonatal intensive care units: an international survey. Neonatology. 2018 Aug 8;114(4):323-331.

Deshpande P, Baczynski M, McNamara P, Jain A. Patent Ductus Arteriosus: The Physiology of Transition. Semin Fetal Neonatal Med. 2018 Aug;23(4):225-231.

6510-Year Report

Duerden EG, Halani S, Ng K, Guo T, Foong J, Glass TJA, Chau V, Branson HM, Sled JG, Whyte HE, Kelly EN, Miller SP. White matter injury predicts disrupted functional connectivity and microstructure in very preterm born neonates. Neuroimage Clin. 2018 Nov 13. pii: S2213-1582(18)30344-9. [Epub ahead of print]

Elboraee MS, Toye J, Ye XY, Shah PS, Aziz K; Canadian Neonatal Network Investigators. Association between Umbilical Catheters and Neonatal Outcomes in Extremely Preterm Infants. Am J Perinatol. 2018 Feb;35(3):233-241.

Elmekkawi A, O’Connor DL, Stone D, Yoon EW, Larocque M, McGeer A, Unger S. The impact of NICU admission on bacterial colonization of human donor milk. J Hum Lact. 2018 May;34(2):350-354.

Esmaeilizand R, Shah PS, Seshia M, Yee W, Yoon EW, Dow K; Canadian Neonatal Network Investigators . Antibiotic exposure and development of necrotizing enterocolitis in very preterm neonates. Paediatr Child Health. 2018 Jul;23(4):e56-e61.

Faden M, McDonald S, Shah PS, Mukerji A. Impact of antenatal corticosteroids in preterm neonates based on maternal body mass index. J Perinatol. 2018 Jul;38(7):818-819.

Fidler L, Sitzer N, Shapera S, Shah PS. Treatment of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis: a systematic review and meta-Analysis. Chest. 2018 Jun;153(6):1405-1415.

Francis J, Vance A, Unger S, Gibbins S, Church P, Bando N, O’Connor DL, on behalf of the GTA DoMINO Feeding Group. Post discharge feeding of very low birth weight infants: Adherence to nutrition guidelines. J Pediatr Gastroenterol Nutr. 2018 Sep;67(3):401-408.

Haslam MD, Lisonkova S, Creighton D, Church P, Yang J, Shah PS,

Joseph KS, Synnes A and the Canadian Neonatal Network and Canadian Neonatal Follow Up Network Investigators. Severe neurodevelopmental impairment in preterm neonates: Impact of varying definitions in a Canadian cohort. J Pediatr. 2018 Jun;197:75-81.e4.

Hunter T, Shah J, Synnes A, Shivananda S, Yang J, Mirea L, Shah PS, Murphy K on behalf of the Canadian Neonatal Network. Neonatal Outcomes of Preterm Twins According to Mode of Birth and Presentation. Journal of Maternal-Fetal and Neonatal Medicine. 2018 Mar;31(5):682-688.

Iwami H, Isayama T, Lodha A, Canning R, Abou Mehrem A, Lee SK, Synnes A, Shah PS; Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators. Outcomes after Neonatal Seizures in Infants Less Than 29 Weeks’ Gestation: A Population-Based Cohort Study. Am J Perinatol. 2019 Jan;36(2):191-199.

Jain A, Mohamed A, Kavanagh B, Shah P, Kuipers B, El-Khuffash A, Mertens L, Jankov R, McNamara P. Cardio-Pulmonary Adaptation during First Day of Life in Humans. J Pediatr. 2018 Sep;200:50-57.e2

Kasirer Y, Shah V, Yoon EW, Bromiker R, Mcnair C, Taddio A. Safety of fentanyl for peripherally inserted central catheter in non-intubated infants in the neonatal intensive care unit. J Perinatol. 2018 May;38(5):526-529.

Keir AK, Karam O, Hodyl N, Stark MJ, Liley HG, Shah PS, Stanworth SJ; NeoBolus Study Group. International, multicentre, observational study of fluid bolus therapy in neonates. J Paediatr Child Health. 2018 Oct 16. doi: 10.1111/jpc.14260. [Epub ahead of print]

Kelly EN, Shah VS, Levenbach J, Vincer M, DaSilva O, Shah PS; Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators. Inhaled and systemic steroid exposure

and neurodevelopmental outcome of preterm neonates. J Matern Fetal Neonatal Med. 2018 Oct;31(20):2665-2672.

Kharrat A, Jain A. Guidelines for the management of acute unexpected cardiorespiratory deterioration in neonates with central venous lines in situ. Acta Paediatr. 2018 Nov;107(11):2024-2025.

Kharrat A, McNamara P, Weisz DE, Jain A. Merits and Perils of Targeted Neonatal Echocardiography-Based Hemodynamic Research: A Position Statement. Can J Physiol Pharmacol. 2018 Oct 16:1-4.

Kjell H, Sjörs G, Shah PS, Modi N, Reichman B, Morisaki N, Kusuda S, Lui K, Darlow B, Bassler D, Hakansson S, Adams M, Vento M, Rusconi F, Isayama T, Lee S, Lehtonen L, for the investigators of the International Network for Evaluating Outcomes (iNeo) of Neonates. Survival in Very Preterm Infants: An International Comparison of 10 National Neonatal Networks. Pediatrics. 2017 Dec;140(6). pii: e20171264.

Koutsokera A, Varughese RA, Sykes J, Orchanian-Cheff A, Shah PS, Chaparro C, Tullis E, Singer LG, Stephenson AL. Pre-transplant factors associated with mortality after lung transplantation in cystic fibrosis: A systematic review and meta-analysis. J Cyst Fibros. 2018 Oct 25. pii: S1569-1993(18)30899-3. [Epub ahead of print]

Lee SK. O’Brien K. Family integrated care: Changing the NICU culture to improve whole-family health. J Neonatal Nurs 2018;24:1-3.

Leibel SL, Ye XY, Shah P, Shah V; Canadian Neonatal Network. Chronic lung disease in preterm infants receiving various modes of noninvasive ventilation at ≤30 weeks’ postmenstrual age. J Matern Fetal Neonatal Med. 2018 Sep 26:1-7. [Epub ahead of print]

Leijser LM, Miller SP, van Wezel-Meijler G, Brouwer AJ, Traubici J, van Haastert IC, Whyte HE,


Groenendaal F, Kulkarni AV, Han KS, Woerdeman PA, Church PT, Kelly EN, van Straaten HLM, Ly LG, de Vries LS. Posthemorrhagic ventricular dilatation in preterm infants: When best to intervene? Neurology. 2018 Feb 20;90(8):e698-e706.

LeMay-Nedjelski L, Copeland J, Wang PW, Butcher J, Unger S, Stintzi A, O’Connor DL Methods and Strategies to Examine the Human Breastmilk Microbiome. Methods Mol Biol. 2018;1849:63-86.

Lodha A, Entz R, Synnes A, Creighton D, Yusuf K, Lapointe A, Yang J, Shah PS; investigators of the Canadian Neonatal Network (CNN) and the Canadian Neonatal Follow-up Network (CNFUN). Early Caffeine Administration and Neurodevelopmental Outcomes in Preterm Infants. Pediatrics. 2019 Jan;143(1). pii: e20181348. Epub 2018 Dec 5.

Louis D, Wong C, Ye XY, McNamara P, Jain A. Factors Associated with Non-response to Second Course Indomethacin for PDA Treatment in Preterm Neonates. J Matern Fetal Neonatal Med. 2018 Jun;31(11):1407-1411.

Louis D, ElSayed YN, Ojah C, Alvaro R, Shah PS, Dunn M; Canadian Neonatal Network Investigators. Predictors of PDA Treatment in Preterm Neonates Who Had Received Prophylactic Indomethacin. Am J Perinatol. 2018 Apr;35(5):509-514.

Magee L, Hutfield A, Hutton E, Helewa M, Gafni A, Robinson W, Koren G, Cote AN, Moutquin JM, Roseboom T, McArthur D, Rey E, Ganzevoort W, Lee S, Chanoine JP, Wilson S, Dorling J, von Dadelszen P, Synnes A, Devlin A, Singer J. CHIPS-Child: Testing the developmental programming hypothesis in the offspring of the CHIPS Trial. Pregnancy Hypertens. 2018 Oct;14:15-22.

Mashally S, Nield LE, McNamara PJ, Martins FF, El-Khuffash A, Jain A, Weisz DE. Late oral

acetaminophen versus immediate surgical ligation in preterm infants with persistent large patent ductus arteriosus. J Thorac Cardiovasc Surg. 2018 Nov;156(5):1937-1944.

More KS, Sakhuja P, Giesinger R, Ting J, Keyzers M, Sheth J, Lapointe A, Jain A, Moore A, Miller S, McNamara P. Cardiovascular Associations with Abnormal Brain Magnetic Resonance Imaging in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia and Rewarming. Am J Perinatol. 2018 Aug;35(10):979-989.

Neary E, Jain A. Right ventricular congestion in preterm neonates with chronic pulmonary hypertension. J Perinatol. 2018 Dec;38(12):1708-1710.

O’Brien K, Robson K, Bracht M, Cruz M, Lui K, Alvaro R, daSilva O, Monterrosa L, Narvey M, Ng E, Soraisham A, Ye XY, Mirea L, Tarnow-Mordi W, Lee SK. Effectiveness of Family Integrated Care in neonatal intensive care units on infant and parent outcomes: a multicentre, multinational, cluster randomised controlled trial. Lancet Child & Adolescent Health. February 7,2018 2(4):245-254.

O’Connor DL, Kiss A, Tomlinson C, Bando N, Bayliss A, Campbell DM, Daneman A, Francis J, Kotsopoulos K, Shah PS, Vaz S, Williams B, Unger S; OptiMoM Feeding Group. Nutrient enrichment of human milk with human and bovine milk-based fortifiers for infants born weighing <1250 g: a randomized clinical trial. Am J Clin Nutr. 2018 Jul 1;108(1):108-116.

Ohlsson A, Shah PS. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants. Cochrane Database Syst Rev. 2018 Apr 6;4:CD010061.

Orlandi S, Raghuram K, Smith CR, Mansueto D, Church P, Shah V, Luther M, Chau Detection of atypical and typical infant movements using computer-based video analysis. Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:3598-3601.

Papadhima I, Louis D, Purna J, Deshpande P, Diambomba Y, Lee S, Shah P, Weisz D, EL-Khuffash A, McNamara P, Mertens L, Jain A. Targeted Neonatal Echocardiography (TNE) Consult Service in a Large Tertiary Perinatal Center in Canada. J Perinatol. 2018 Aug;38(8):1039-1045.

Persson M, Shah PS, Rusconi F, Reichman B, Modi N, Kusuda S, Lehtonen L, Håkansson S, Yang JM, Isayama T, Beltempo M, Lee S, Norman M, on behalf of iNeo. Association of Maternal Diabetes With Neonatal Outcomes of Very Preterm and Very Low-Birth-Weight Infants: An International Cohort Study. JAMA Pediatr. 2018 Sept1;172(9):867-875.

Raghuram K, Dunn M, Jangaard K, Reilly M, Asztalos E, Kelly E, Vincer M, Shah V. Inhaled corticosteroids in ventilated preterm neonates: a non-randomized dose-ranging study. BMC Pediatr. 2018 May 7;18(1):153.

Raphael J, Desautels D, Pritchard KI, Petkova E, Shah PS. Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis. European Journal of Cancer 2018;91:38-46.

Razak A, Florendo-Chin A, Banfield L, Abdul Wahab M, McDonald S, Shah PS, Mukerji A. Pregnancy induced hypertension and neonatal outcomes: a systematic review and metaanalysis. J Perinatol 2018 Jan;38(1):46-53.

Razak A, Patel W, Durrani N, McDonald SD, Vanniyasingam T, Thabane L, Shah PS, Mukerji A. Neonatal respiratory outcomes in pregnancy induced hypertension: introducing a novel index. J Matern Fetal Neonatal Med. 2018 Sep 6:1-8.

Ronzoni S, Windrim R, Seaward G, Kelly E, Shah PS, Ryan G. Management and neonatal outcomes of pregnancies with a previous history of F/NAIT: a single center retrospective cohort study. Fetal Diagn Ther. 2019;45(2):85-93.

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Roth DE, Morris SK, Zlotkin S, Gernand AD, Ahmed T, Shanta SS, Papp E, Korsiak J, Shi J, Islam MM, Jahan I, Keya FK, Willan AR, Weksberg R, Mohsin M, Rahman QS, Shah PS, Murphy KE, Stimec J, Pell LG, Qamar H, Al Mahmud A. Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth. N Engl J Med. 2018 Aug 9;379(6):535-546.

Stall NM, Kim SJ, Hardacre KA, Shah PS, Straus SE, Bronskill SE, Lix LM, Bell CM, Rochon PA Association of Informal Caregiver Distress with Health Outcomes of Community-Dwelling Dementia Care Recipients: A Systematic Review. J Am Geriatr Soc. 2018 Dec 10. doi: 10.1111/jgs.15690. [Epub ahead of print]

Shah P, Kei L, Sjörs G, Mirea L, Reichman B, Adams M, Modi N, Darlow BA, Kusuda S, San Feliciano L, Yang JM, Hakansson S, Mori R, Bassler D, Figueras-Aloy J, Lee SK. Country-specific versus common birthweight for gestational age references to identify small for gestational age infants born at 24 to 28 weeks: an international study. Paediatr Perinat Epidemiol. 2016 Sep;30(5):450-61.

Shah PS, Acharya G. Comparative effectiveness research using registries, databases, and networks in women’s and children’s health: Time to embrace the future? Acta Obstet Gynecol Scand. 2018 Nov;97(11):1285-1286.

Shah PS, Dunn M, Aziz K, Shah V, Deshpandey A, Mukerji A, Ng E, Mohammad K, Ulrich C, Amaral N, Lemyre B, Synnes A, Piedboeuf B, Yee WH, Ye XY, Lee SK. Sustained Quality Improvement in Outcomes of Preterm Neonates of <29 Weeks’ Gestational Age: Results from the Evidence-based Practice for Improving Quality Phase 3 (EPIQ-3).Can J Physiol Pharmacol. 2018 Oct 1. doi: 10.1139/cjpp-2018-0439.

Shah PS, Kusuda S, Håkansson S, Reichman B, Lui K, Lehtonen L, Modi N, Vento M, Adams M, Rusconi F, Norman M, Darlow

BA, Lodha A, Yang J, Bassler D, Helenius KK, Isayama T, Lee SK; International Network for Evaluation of Outcomes (iNEO) in Neonates Investigators. Neonatal Outcomes of Very Preterm or Very Low Birth Weight Triplets. Pediatrics. 2018 Dec;142(6). pii: e20181938.

Shah PS, McDonald SD, Barrett J, Synnes A, Robson K, Foster J, Pasquier JC, Joseph KS, Piedboeuf B, Lacaze-Masmonteil T, O’Brien K, Shivananda S, Chaillet N, Pechlivanoglou P on behalf of Canadian preterm Birth Network Investigators. The Canadian Preterm Birth Network: A study protocol for improving outcomes for preterm infants and their families. CMAJ Open. 2018 Jan 18;6(1):E44-E49.

Shah V, Hodgson K, Seshia M, Dunn M, Schmölzer GM. Golden hour management practices for infants <32 weeks gestational age in Canada. Paediatr Child Health. 2018 Jul;23(4):e70-e76.

Stockley EL, Ting JY, Kingdom JC, McDonald SD, Barrett JF, Synnes AR, Monterrosa L, Shah PS; Canadian Neonatal Network; Canadian Neonatal Follow-up Network; Canadian Preterm Birth Network Investigators. Intrapartum magnesium sulfate is associated with neuroprotection in growth-restricted fetuses. Am J Obstet Gynecol. 2018 Dec;219(6):606.e1-606.e8.

Stritzke A, Mohammad K, Shah PS, Ye XY, Bhandari V, Akierman A, Harrison A, Bertelle V, Lodha A. Use and timing of surfactant administration: impact on neonatal outcomes in extremely low gestational age infants born in Canadian Neonatal Intensive Care Units. J Matern Fetal Neonatal Med. 2018 Nov;31(21):2862-2869.

Taddio A, Shah V, Bucci L, MacDonald NE, Wong H, Stephens Defectiveness of a hospital-based postnatal parent education intervention about pain management during infant vaccination: a randomized controlled trial during

infant vaccination: a randomized controlled trial. CMAJ. 2018 Oct 22;190(42):E1245-E1252.

Tam J, Lee SJ, Shah V, Morris SK. Successful Treatment of High-Level Aminoglycoside-Resistant Enterococcus faecalis Bacteremia in a Preterm Infant with Ampicillin and Cefotaxime. Case Rep Infect Dis. 2018 Mar 18;2018:7567914.

Ting J, Roberts A, Synnes A, Canning R, Bodani J, Monterossa L, Shah PS for the Canadian Neonatal Network Investigators. Invasive fungal infections in neonates in Canada: epidemiology and outcomes. Pediatr Infect Dis J. 2018 Nov;37(11):1154-1159.

Ting J, Synnes A, Lee SK, Shah P, Canadian Neonatal Network, Canadian Neonatal Follow-Up Network. Association of Admission Temperature and Death or Adverse Neurodevelopmental Outcomes in Extremely-low-gestational-age-neonates. J Perinatol. 2018 Jul;38(7):844-849.

Ting JY, Kingdom JC, Shah PS. Antenatal glucocorticoids, magnesium sulfate and mode of birth in preterm fetal small for gestational age. Am J Obstet Gynecol. 2018 Feb;218(2S):S818-S828.

Ting JY, Synnes A, Roberts A, Deshpandey AC, Dow K, Yang J, Lee KS, Lee SK, Shah PS, on behalf of the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network. Association of antibiotic utilization and neurodevelopmental outcomes among extremely low gestational age neonates without proven sepsis or necrotizing enterocolitis. Am J Perinatol. 2018 Aug;35(10):972-978.

Trang S, Zupancic J, Unger S, Kiss A, Bando N, Wong S, Gibbins S, O’Connor D; GTA-DoMINO Feeding Group. Cost-effectiveness of Supplemental Donor Milk Versus Formula for Very Low Birth Weight Infants. Pediatrics. 2018 Mar;141(2): pii: e20170737.


von Dadelszen P, Magee LA, Benton SJ, Hu Y, Ansermino JM, Carleton B, Carter C, Douglas MJ, Janssen PA, Lee SK, Leung PCK, Li J, MacNab Y, Payne BA, Peng G, Rodger M, Skoll MA, Synnes A, Walley KR, Russell JA. Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial. Pregnancy Hypertens. 2018 Jul;13:121-126.

van Dyk J, Church P, Dell S, To T, Luther M, Shah V. Prediction of long-term neurodevelopmental outcome in preterm infants using trajectories of general movement assessments. J Perinatol. 2018 Oct;38(10):1398-1406.

Wallis CJD, Klaassen Z, Bhindi B, Ye XY, Chandrasekar T, Farrell AM, Goldberg H, Boorjian SA, Leibovich B, Kulkarni GS, MD, Shah PS, Bjarnason GA, Heng D, Satkunasivam R, Finelli A. First-line Systemic Therapy for Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-analysis. Eur Urol. 2018 Apr 13. pii:S0302-2838(18)30254-9.

Weisz D, Mirea L, Resende M, Ly L, Church P, Kelly E, Kim SJ, Jain A, McNamara P, Shah P. Persistent Patent Ductus Arteriosus after Unsuccessful Pharmacotherapy: Association of Surgical Ligation with Neonatal and Neurodevelopmental Outcomes. J Pediatr. 2018 Apr;195:292-296.e3.

Wilson A, Vento M, Shah PS, Saugstad O, Finer N, Rich W, Morton R, Rabi Y, Tarnow-Mordi W, Suzuki K, Wright IM, Oei J A. A review of international clinical practice guidelines for the oxygen use during preterm resuscitation. Acta Paediatr. 2018 Jan;107(1):20-27.

Wong H, Moss C, Moss SM, Shah V, Halperin SA, Ito S, Mithal P, Qu A, Taddio A. Effect of alcohol skin cleansing on vaccination-associated infections and local skin reactions: a randomized controlled trial. Hum Vaccin Immunother. 2018 Dec 4. doi: 10.1080/21645515.2018.1553474.

Yusuf K, Alshaikh B, da Silva O, Lodha A, Alvaro R, Wilson R, Lee SK, Shah PS and Canadian Neonatal Network Investigators. Neonatal outcomes of extremely preterm infants exposed to maternal hypertension and cigarette smoking. J Perinatol 2018 Sug;38(8):1051-1059.

2017Acuna SA, Huang JW, Daly CA, Shah PS, S. Joseph Kim, Baxter NN. Outcomes of solid organ transplant recipients with preexisting malignancies in remission: A systematic review and meta-analysis. Transplantation. 2017 Mar; 101(3):471-481.

Alali AS, Mukherjee K, McCredie VA, Golan E, Shah PS, Bardes JM, Hamblin SE, Haut ER, Jackson JC, Khwaja K, Patel NJ, Raj SR, Wilson LD, Nathens AB, Patel MB. Beta-Blockers and Traumatic Brain Injury: A Systematic Review, Meta-analysis, and Eastern Association for the Surgery of Trauma Guideline. Ann Surg. 2017 Dec;266(6):952-961.

Al-Ghanem G, Shah PS, Thomas S, Banfield L, El Helou S, Fusch C, Mukerji A. Pulmonary hypertension and bronchopulmonary dysplasia: a meta-analysis. J Perinatol. 2017 Apr;37(4):414-419.

Baczynski M, Ginty S, Kelly E, Weisz D, McNamara P, Shah PS, Jain A. Short and long-term outcomes of preterm neonates with acute severe pulmonary hypertension following rescue treatment with inhaled nitric oxide. Arch Dis Child Fetal Neonatal Ed. 2017 Nov;102(6):F508-F514.

Barton M, Shen A, O’Brien K, Robinson JL, Davies HD, Simpson K, Asztalos E, Langley J, Le Saux N, Sauve R, Synnes A, Tan B, Repentigny L, Rubin E, Hui C, Kovacs L, Yau YC, Richardson SE and the Pediatric Investors Collaborative Network on Infections in Canada. Early Onset Invasive Candidiasis in Extremely Low Birth

Weight Infants: Perinatal Acquisition Predicts Poor Outcome. Clinical Infectious Diseases. Clin Infect Dis. 2017 Apr 1;64(7):921-927.

Borenstein-Levin L, Synnes A, Grunau RE, Miller SP, Yoon EW, Shah PS for the Canadian Neonatal Network Investigators. Narcotics and Sedative use in Preterm Neonates. J Pediatr. 2017 Jan;180:92-98.e1.

Brunsek A, Perlman M, Falenchuk O, McMullen E, Fletcher B, Shah PS. The Relationship between the Early Childhood Environment Rating Scale and its Revised Form and Child Outcomes: A Systematic Review and Meta-Analysis. PLoS One. 2017 Jun 6;12(6):e0178512.

D’Souza R, Ostro J, Malinowski A, Silversides CK, Murphy KE, Sermer M, Shah PS, Shehata N. Anticoagulation for pregnant women with mechanical heart valves: A systematic review and meta-analysis. Eur Heart J. 2017 May 14;38(19):1509-1516.

Da Luz LT, Marchand M, Nascimento B, Tien H, Nathens A, Shah PS. Efficacy and safety of the drugs used to reverse the novel oral anticoagulants: a systematic review and meta-analyses. Transfusion. 2017 Jul;57(7):1834-1846.

Darlow BA, Lui K, Kusuda S, Reichman B, Håkansson S, Bassler D, Modi N, Lee SK, Lehtonen L, Vento M, Isayama T, Sjörs G, Helenius KK, Adams M, Rusconi F, Morisaki N, Shah PS, on behalf of the International Network for Evaluating Outcomes (iNeo) of Neonates. International variations and trends in the treatment for retinopathy of prematurity. Br J Ophthalmol. 2017 Oct;101(10):1399-1404.

El-Rabbany M, Sgro A, Lam DK, Shah PS, Azarpazhooh A. Effectiveness of Treatments of Medication-Related Osteonecrosis of the Jaw: A Systematic Review and Meta-Analysis. J Am Dent Assoc. 2017 Aug;148(8):584-594.e2.

6910-Year Report

Esmaeilizand R, Shah PS, Seshia M, Yee W, Yoon E, Dow K, for the Canadian Neonatal Network Investigators. Antibiotic Exposure and Development of Necrotizing Enterocolitis in Very Preterm Neonates. Paediatr Child Health. https://doi.org/10.1093/pch/pxx169

Ethier JL, Desautels D, Templeton A, Shah PS, Amir E. Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis. Breast Cancer Res. 2017 Jan 5;19(1):2.

Hines D, Modi N, Lee SK, Isayama T, Sjörs G, Gagliardi L, Lehtonen L, Vento M, Kusuda S, Bassler D, Mori R, Reichman B, Håkansson S, Darlow BA, Adams M, Rusconi F, San Feliciano L, Lui K, Morisaki N, Musrap N, Shah PS for International Network for Evaluating Outcomes (iNeo) of Neonates. Scoping review shows wide variation in the definitions of bronchopulmonary dysplasia in preterm infants and calls for a consensus. Acta Paediatr. 2017 Mar;106(3):366-374.

Hodgson K, Dunn M, Seshia M, Schmölzer GM, Shah V. Golden Hour Management Practices for Infants < 32 weeks Gestational Age in Canada. J Pediatr Child Health. 2017 Jul; 53:44-45.

Hogan ME, Taddio A, Katz J, Shah V, Krahn M. Health utilities in people with chronic pain using a population-level survey and linked health care administrative data. Pain 2017;158(3):408-416.

Hunter T, Shah J, Synnes A, Shivananda S, Ryan G, Shah PS, Murphy KE on behalf of the Canadian Neonatal Network. Neonatal Outcomes of Preterm Twins According to Mode of Birth and Presentation. J Matern Fetal Neonatal Med. 2017 Mar 8:1-7.

Isayama T, Lee SK, Yang J, Lee D, Daspal S, Dunn M, Shah PS for Canadian Neonatal Network and Canadian Neonatal Follow Up Network Investigators. BPD definition revisited: impact of changing panoply of respiratory

support for preterm neonates. JAMA Pediatr. 2017 Mar 1;171(3):271-279.

Jarde A, Lutsiv O, Park CK, Barrett J, Beyene J, Saito S, Dodd JM, Shah PS, Cook JL, Biringer AB, Giglia L, Han Z, Staub K, Mundle W, Chamberlain J, Vera C, Lopez-Yarto M, Sabatino L, Liyanage SK, McDonald SD. Preterm birth prevention in twin pregnancies with progesterone, pessary or cerclage: a systematic review and meta-analysis. BJOG. 2017 Jul;124(8):1163-1173.

Jarde A, Lutsiv O, Park CK, Beyene J, Dodd JM, Barrett J, Shah PS, Cook JL, Saito S, Biringer AB, Sabatino L, Giglia L, Han Z, Staub K, Mundle W, Chamberlain J, McDonald SD. Effectiveness of progesterone, cerclage and pessary for preventing preterm birth in singleton pregnancies: A systematic review and network meta-analysis. BJOG. 2017 Jul;124(8):1176-1189.

Kelly EN, Shah VS, Levenbach J, Vincer M, DaSilva O, Shah PS; Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators. Inhaled and systemic steroid exposure and neurodevelopmental outcome of preterm neonates. J Matern Fetal Neonatal Med 2017;16:1-8.

Kelly LE, Shah PS, Håkansson S, Kusuda S, Adamse M, Lee SK, Sjörs G, Vento M, Rusconi F, Lehtonen L, Reichmani B, Darlow BA, Lui K, Feliciano LF, Gagliardi L, Basslere D, Modim N, International Network for Evaluating Outcomes (iNeo) of Neonates. Perinatal health services organization for preterm births: a multinational comparison. J Perinatol. 2017 Jul;37(7):762-768.

Koller-Smith L, Shah PS, Ye XY, Sjörs G, Wang YA, Chow SW, Darlow BA, Lee SK, Håkkanson S, Lui K on behalf of the Australian and New Zealand Neonatal Network, Canadian Neonatal Network and Swedish Neonatal Quality Register. Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants. BMC Pediatrics. 17:166.

Li XY, Lee SK , Liu JH, Ye XY, YuHF, Liu XH. Breaking down barriers: Enabling care-by-parent in neonatal intensive care units in China. World J Pediatr. 2017 Apr;13(2):144-151.

Lokku A, Mirea L, Lee SK, Shah PS on behalf of the Canadian Neonatal Network. Trends and Outcomes of Patent Ductus Arteriosus Treatment in Very Preterm Infants in Canada. Am J Perinatol. 2017 Apr;34(5):441-450.

Lyu Y, Ye XY, Isayama T, Alvaro R, Nwaesi C, Barrington K, Lee SK, Shah PS. Systolic Blood Pressure at Admission and Neonatal Outcomes in Preterm Infants of ≤26 Weeks Gestational Age. Am J Perinatol. 2017 Nov;34(13):1271-1278.

Mei-Dan E, Chundalama J, Shah P, Shah J, Lee SK, Murphy K. The Effect of Birth Order on Neonatal Morbidity and Mortality in Very Preterm Twins. Am J Perinatol. 2017 Jul;34(9):845-850.

Mukerji A, Sarmiento K, Lee B, Hassall K, Shah V. Non-invasive high-frequency ventilation versus bi-phasic continuous positive airway pressure (BP-CPAP) following CPAP failure in infants <1250 g: a pilot randomized controlled trial. J Perinatol 2017;37(1):49-53.

Mukerji A, Shah PS, Shivananda S, Yee W, Read B, Minski J, Alvaro R, Fush C for the Canadian Neonatal Investigators. Non-invasive respiratory support practices in Canadian neonatal intensive care units: a survey. Acta Paediatr. 2017 Mar;106(3):387-393.

Murphy K, Coo H, Warre R, Shah V, Dow K. Variations and similarities in clinical management of neonatal abstinence syndrome: Findings of a Canadian survey. Paediatr Child Health. 2017Jun;22(3):148-152.

Ng DVY, Unger S, Asbury M, Kiss A, Bishara R, Bando N, Tomlinson C, Gibbins S, O’Connor DL; GTA-DoMINO Feeding Group. Neonatal morbidity count is associated with a reduced likelihood of achieving recommendations for protein, lipids, and energy in very low birth weight


infants: A prospective cohort study. JPEN J Parenter Enteral Nutr. 2017 May 1:148607117710441.

Perlman M, Falenchuk O, Fletcher B, McMullen E, Beyene J, Shah PS. A Systematic Review and Meta-Analysis of a Measure of Staff/Child Interaction Quality (the Classroom Assessment Scoring System) in Early Childhood Education and Care Settings and Child Outcomes. PLoS One. 2016 Dec 30;11(12):e0167660.

Perlman M, Fletcher B, Falenchuk O, Bruncek A, McMullen E, Shah PS. Child-staff ratios in early childhood education and care programs and child outcomes: a systematic review and meta-analysis. PLoS One. 2017 Jan 19;12(1):e0170256.

Raghuram K, Mukerji A, Young J, Yee W, Seshia M, Dow K, Shah V. Surfactant utilization and short-term outcomes in an era of non-invasive respiratory support in Canadian neonatal intensive care units. J Perinatol. 2017 Sep;37(9):1017-1023.

Raghuram K, Yang J, Church PT, Cieslak Z, Synnes A, Mukerji A, Shah PS, for the Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators. Head growth trajectory and neurodevelopmental outcomes in preterm neonates. Pediatrics. 2017 Jul;140(1).

Ray JG, Bartsch E, Park AL, Shah PS, Dzakpasu S. Estimated reductions in provider-initiated preterm birth and maternal and newborn hospital length of stay under a universal aspirin prophylaxis strategy in Canada. CMAJ Open. 2017 Apr-Jun; 5(2):E508-E516.

Shah PS, Seidlitz W, Chan P, Yeh S, Musrap N, Lee SK, on behalf of data abstractors of the Canadian Neonatal Network. Internal audit of the Canadian Neonatal Network data collection system. Am J Perinatol. 2017 Oct;34(12):1241-1249.

Shah P, Shah V, Kelly L. Arginine supplementation for prevention of necrotizing enterocolitis. Cochrane Database Syst Rev. 2017 Apr 11;4:CD004339.

Shah PS. Neonatal Intensive Care – The only constant is change. New Engl J Med 2017 376:694-6.

Shah VS, Ohlsson A, Halliday HL, Dunn M. Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates. Cochrane Database Syst Rev 2017;1:CD001969.

Shalabi M, Adel M, Lemyre B, Aziz K, Kalapesi Z, Faucher D, Shah PS for the investigators of the Canadian Neonatal Network. Antenatal exposure to magnesium sulphate and spontaneous intestinal perforation and necrotizing enterocolitis in very preterm neonates. Am J Perinatol. 2017 Oct;34(12):1227-1233.

Sharma R, Buccioni M, Gaffey MF, Mansoor O, Scott H, Bhutta ZA, and The Canadian Expert Group on Maternal, Newborn, Child and Adolescent Health (Shah PS). Setting an Implementation Research Agenda for Canadian Investments in Global Maternal, Newborn, Child and Adolescent Health: A Research Prioritization Exercise. CMAJ Open. 2017 Jan 31;5(1):E82-E89.

Silver S, Bell CM, Chertow CM, Shah PS, Shojania K, Wald R, Harel Z. Effectiveness of quality improvement strategies for the management of chronic kidney disease: a meta-analysis. Clin J Am Soc Nephrol. 2017 Oct 6;12(10):1601-1614.

Soraisham AS, Rabi Y, Singhal N, Synnes A, Yang J, Shah PS, Lee SK, Lodha AK for investigators of the Canadian Neonatal Network and Canadian Neonatal Follow up Network. Neurodevelopmental Outcomes of preterm infants based on receipt of oxygen concentration at birth. J Perinatol. 2017 Oct; 37(10):1141-1147.

Stavel M, Wong J, Cieslak Z, Sherlock R, Claveau M, Shah PS and the Canadian Neonatal Network Investigators. Effect of combination of prophylactic indomethacin administration and early feeding on

spontaneous intestinal perforation in extremely low birth weight infants. J Perinatol. 2017 Feb;37(2):188-193.

Urban D, Pluthero FG, Christensen H, Das A, Baidya S, Rand ML, Shah PS, Chitayat D, Blanchette V, Kahr WHA. Decreased numbers of dense granules in fetal and neonatal platelets. Haematologica. 2017 Feb;102(2):e36-e38.

Weisz DE, Mirea L, Rosenberg E, Jang M, McNamara PJ, Kim JS, Ly L, Church PT, Kelly E, Shah PS. Association of Patent Ductus Arteriosus Ligation and Death or Neurodevelopmental Impairment in Extremely Preterm Infants. JAMA Pediatr. 2017 May 1;171(5):443-449.

Wong J, Finan E, Campbell D. Use of Simulation in Canadian Neonatal-Perinatal Medicine Training Programs. Cureus. 2017 Jul 8;9(7):e1448.

Zizzo AN, Valentino P, Shah PS, Kamath B. Second-line agents in pediatric patients with autoimmune hepatitis: a systematic review and meta-analysis. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):6-15.

2016Acuna SA, Elmi M, Shah PS, Coburn NG, Quereshy FA. Preoperative localization of colorectal cancer: a systematic review and meta-analysis. Surg Endosc. 2017 Jun;31(6):2366-2379.

Ahmed RJ, Gafni A, Hutton EK, Hu ZJ, Pullenayegum E, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gruslin A, Ganzevoort W, Helewa M, Lee SK, Lee T, Logan AG, Moutquin JM, Singer J, Thornton JG, Welch R, Magee LA, CHIPS Trial Collaborative Group. The Cost Implications of ‘Less Tight’ Versus ‘Tight’ Control of Hypertension In Pregnancy (CHIPS Trial). Hypertension. 2016 Oct;68(4):1049-55.

Asztalos EV, Church PT, Faucher D, Riley P, Fajardo C, Shah PS for the Canadian Neonatal Network

7110-Year Report

and Canadian Neonatal Follow Up Network Investigators. Association of Maternal/primary Caregiver Education and Cognitive and Language Development of Preterm Neonates. Am J Perinatol. 2017 Mar;34(4):364-371.

Asztalos EV, Church PT, Riley P, Fajardo C, Shah PS; Canadian Neonatal Network and Canadian Neonatal Follow-up Network Investigators. Neonatal Factors Associated with a Good Neurodevelopmental Outcome in Very Preterm Infants. Am J Perinatol. 2017 Mar;34(4):388-396.

Azarpazhooh A, Lawrence HP, Shah PS. Xylitol for preventing acute otitis media in children under 12 years of age. Cochrane Database Syst Rev. 2016 Aug 3;8:CD007095.

Baczynski M, Ginty S, Weisz D, McNamara P, Kelly E, Shah P, Jain A. Short and Long-Term Outcomes of Preterm Neonates with Acute Severe Pulmonary Hypertension Following Rescue Treatment with Inhaled Nitric Oxide. Arch Dis Child Fetal Neonatal Ed. 2017 Nov;102(6):F508-F514.

Bhatia A, Flamer D, Shah PS. Transforaminal epidural steroid injections for treating lumbosacral radicular pain from herniated intervertebral discs: a systematic review and meta-analysis. Anesth Analg. 2016 Mar;122(3):857-70.

Bielecki JM, Wong J, Mitsakakis N, Shah PS, Krahn MD, Rac VE. Disparities in a provision of in-hospital post-arrest interventions for out-of-hospital cardiac arrest (OHCA) in the elderly population - protocol for a systematic review. Syst Rev. 2016 Apr 7;5:55.

Carnaghan H, Baud D, Lapidus-Krol E, Ryan G, Shah PS, Pierro A, Eaton S. Effect of gestational age at birth on neonatal outcomes in gastroschisis. J Pediatr Surg. 2016 May;51(5):734-8.

Chang E, Lam E, Shah PS, Azarpazhooh A. Cone Beam Computed Tomography for Detecting Vertical Root Fractures

in Endodontically-Treated Teeth: A Systematic Review. J Endod. 2016 Feb;42(2):177-85.

Cordeiro E, Gervais MK, Shah PS, Look-Hong N, Wright F. Sentinel Lymph Node Biopsy in Thin Cutaneous Melanoma: A Systematic Review and Meta-Analysis. Ann Surg Oncol. 2016 Dec;23(13):4178-4188.

Deshpande P, Jain A, Shah P. Shah J. Outcomes associated with catheter retention vs. removal after diagnosis of catheter associated infections in neonates. Matern Fetal Neonatal Med. 2016 Mar 18:1-6.

Deshpande P, Jain A, Shah PS. Outcomes associated with catheter retention vs. removal after diagnosis of catheter associated infections in neonates. J Matern Fetal Neonatal Med. 2016 Dec;29(24):4082-7.

Di Laura S, Unger S, Stone D, O’Connor DL. Human milk for VLBW and medically compromised infants: Strategies and ongoing innovation. JPEN J Parenter Enteral Nutr. 2016 Aug;40(6):768-82.

Ee M, Kantores C, Ivanovska J, Wong M, Jain A, Jankov R. Leukotriene B4 Mediates Macrophage Influx and Pulmonary Hypertension in Bleomycin-induced Chronic Neonatal Lung Injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L292-302.

Fleeman N, Mahon J, Bates V, Dickson R, Dundar Y, Dwan K, Ellis L, Kotas E, Richardson M, Shah PS, Shaw BN. The clinical effectiveness and cost-effectiveness of heated humidified high-flow nasal cannula compared with usual care for preterm infants: systematic review and economic evaluation. Health Technol Assess. 2016 Apr;20(30):1-68.

Gajic-Veljanoski O, Phua CW, Shah PS, Cheung A. Effect of long-term low-molecular-weight heparin on fractures and bone density in non-pregnant adults: A systematic review with meta-analysis. J Gen Intern Med. 2016 Aug;31(8):947-57.

Gemmell L, Martin L, Murphy K, Modi N, Håkansson S, Reichman B, Kei L, Kusuda S, Sjörs G, Mirea L, Darlow BA, Mori R, Lee SK, Shah PS, International Network for Evaluating Outcomes (iNeo) of Neonates Investigators. Hypertensive Disorders of Pregnancy and Neonatal Outcomes of preterm neonates 24-28 weeks gestation: An International Retrospective Cohort Study. J Perinatol. 2016 Dec;36(12):1067-1072.

Harrison D, Reszel J, Bueno M, Sampson M, Shah VS, Taddio A, Larocque C, Turner L. Breastfeeding for procedural pain in infants beyond the neonatal period. Cochrane Database Syst Rev. 2016 Oct 28;10:CD011248.

Hei MY, Gao XY, Gao XR, Nong SH, Zhang AM, Zhang QS, Lee SK. Is family integrated care in NICUs feasible and good in China: study protocol for a cluster randomized controlled trial. Trials 2016,17:22.

Hemsworth EM, O’Reilly AM, Allen VM, Kuhle S, Brock JK; Knowledge Synthesis Group on Determinants of Preterm/LBW Births. Association Between Factor V Leiden Mutation, Small for Gestational Age, and Preterm Birth: A Systematic Review and Meta-Analysis. J Obstet Gynaecol Can 2016;38(10):897-908.

Hines D, Modi N, Lee SK, Isayama T, Sjörs G, Gagliardi L, Lehtonen L, Vento M, Kusuda S, Bassler D, Mori R, Reichman B, Håkansson S, Darlow BA, Adams M, Rusconi F, San Feliciano L, Lui K, Morisaki N, Musrap N, Shah PS, International Network for Evaluating Outcomes (iNeo) of Neonates. Scoping review shows wide variation in the definitions of bronchopulmonary dysplasia in preterm infants and calls for a consensus. Acta Paediatr. 2017 Mar;106(3):366-374.

Hogan ME, Taddio A, Katz J, Shah V, Krahn M. Incremental health care costs for chronic pain in Ontario, Canada: a population-based matched cohort study of adolescents and adults


using administrative data. Pain 2016;157(8):1626-33.

Hogan ME, Taddio A, Katz J, Shah V, Krahn M. Incremental health care costs for chronic pain in Ontario, Canada: a population-based matched cohort study of adolescents and adults using administrative data. Pain 2016;157(8):1626-33.

Hossain S, Shah PS, Ye XY, Darlow B, Lee SK, Lui K on behalf of the Canadian Neonatal Network and Australian and New Zealand Neonatal Network. Outborns or inborns, where are the differences? A comparison study of very preterm NICU infants cared for in Australia and New Zealand and in Canada. Neonatology. 2016;109(1):76-84.

Isayama T, Lee SK, Yang JM, Lee DSC, Daspal S, Dunn M, Shah PS, Canadian Neonatal Network and Canadian Neonatal Follow-Up Network Investigators. Revisiting the definition of bronchopulmonary dysplasia: impact of changing panoply of respiratory support for preterm neonates. JAMA Pediatr. 2017 Mar 1;171(3):271-279.

Jain A, EL-Khuffash A, Kuipers B, Mohamed A, Connelly K, McNamara P, Jankov R, Mertens L. Left Ventricular Function in Healthy Term Neonates During the Transitional Period. J Pediatr. 2016 Nov 28. Pii: S0022-3476(16)31231-8.

Jiang S, Lv Y, Ye X, Monterrosa L, Shah PS, Lee SK and CNN investigators. Intensity of delivery room resuscitation in infants born at 33 and 36 weeks’ gestation. J Perinatol. 2016 Feb;36(2):100-5.

King, SK, Alfaraj, M, Gaiteiro, R, O’Brien, K, Moraes, T, Humpl, T, Marcon, M, Chiang, M, Reyes, J, Haliburton, B, Ryan, G, Cox, P, Chiu, P.P.L. Congenital diaphragmatic hernia: Observed/expected lung-to-head ratio as a predictor of long-term morbidity. Journal of Pediatric Surgery. 2016 51(5):699-702.

Langhoff-Roos J, Shah PS. Evidence-based guidelines and

consensus statements. Acta Obstet Gynecol Scand. 2016 Aug;95(8):843-4.

Lee SK. Implementing evidence based practices improves neonatal outcomes. Evid Based Med. 2016 Dec;21(6):231.

Levy PT, El-Khuffash A, Patel MD, Breatnach CR, James AT, Sanchez AA, Abuchabe C, Rogal SR, Holland MR, McNamara PJ, Jain A, Franklin O, Mertens L, Hamvas A, Singh GK. Maturational Patterns of Systolic Ventricular Deformation Mechanics by Two-Dimensional Speckle-Tracking Echocardiography in Preterm Infants over the First Year of Age. J Am Soc Echocardiogr. 2017 Jul;30(7):685-698.e1.

Louis D, Shah J, Torgalkar R, Shah PS, Jain A. Enteral feeding during indomethacin treatment for patent ductus arteriosus: Association with gastrointestinal outcomes. J Perinatol. 2016 Jul;36(7):544-8.

Louis D, Wong C, Ye X, McNamara P, Jain A. Clinical Predictors of Non-Response to Second Course Indomethacin for PDA Treatment in Preterm Neonates. J Matern Fetal Neonatal Med. 2017 May 2:1-5.

Magee LA, von Dadelszen P, Singer J, Lee T, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gafni A, Grusin A, Helewa M, Hutton E, Lee SK, Logan AG, Ganzevoort W, Welch R, Thornton JG, Mooutquin JM. Can adverse maternal and perinatal outcomes be predicted when blood pressure becomes elevated? Secondary analyses from the CHIPS (Control of Hypertension In Pregnancy Study) randomized controlled trial. Acta Obstetr Gynecol Scand 2016;95:763–776.

Magee LA, von Dadelszen P, Singer J, Lee T, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gafni A, Helewa M, Hutton E, Koren G, Lee SK, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM, CHIPS Study Group. The CHIPS Randomized Controlled Trial (Control of Hypertension

in Pregnancy Study): Is Severe Hypertension Just an Elevated Blood Pressure? Hypertension. 2016 Nov;68(5):1153-1159.

Makikallio K, Shah J, Slorach C, Qin H, Kingdom J, Keating S, Kelly E, Manlhiot C, Redington A, Jaeggi E. Fetal growth restriction and cardiovascular outcome in early human infancy: a prospective longitudinal study. Heart vessels. 2016 Sep;31(9):1504-13.

Mankouski A, Kantores C, Wong M, Ivanovska J, Jain A, Benner E, Mason S, Tanswell AK, Auten R, Jankov R. Intermittent Hypoxia During Recovery from Neonatal Hyperoxic Lung Injury Causes Long-Term Impairment of Alveolar Development: A New Rat Model of BPD. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L208-L216.

Martin LJ, Sjörs G, Reichman B, Darlow BA, Morisaki N, Modi N, Bassler D, Mirea L, Adams M, Kusuda S, Lui K, Feliciano LS, Håkansson S, Isayama T, Mori R, Vento M, Lee SK, Shah PS; International Network for Evaluating Outcomes (iNeo) of Neonates Investigators. Country-Specific vs. Common Birthweight-for-Gestational Age References to Identify Small for Gestational Age Infants Born at 24-28 weeks: An International Study. Paediatr Perinat Epidemiol. 2016 Sep;30(5):450-61.

McMurtry CM, Taddio A, Noel M, Antony MM, Chambers CT, Asmundson GJ, Pillai Riddell R, Shah V, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E, Halperin S, Bowles S, Halpert C, Ipp M, Rieder MJ, Robson K, Uleryk E, Votta Bleeker E, Dubey V, Hanrahan A, Lockett D, Scott J. Exposure-based Interventions for the management of individuals with high levels of needle fear across the lifespan: a clinical practice guideline and call for further research. Cogn Behav Ther 2016;45(3):217-35.

Melamed N, Pettini A, Barrett J, Shah J, Yoon E, Lemyre B, Lee SK, Murphy KE, Shah

7310-Year Report

PS for the Canadian Neonatal Network Investigators. Antenatal Corticosteroids and Outcomes of Small for Gestational Age Neonates. Obstet Gynecol. 2016 Nov;128(5):1001-1008.

Melamed N, Shah J, Yoon EW, Pelausa E, Lee S, Shah PS, Murphy KE; Canadian Neonatal Network Investigators. The role of antenatal corticosteroids in twin pregnancies complicated by preterm birth. Am J Obstet Gynecol. 2016 Oct;215(4):482.e1-9.

Morin J, Luu TM, Superstein R, Ospina LH, Lefebvre F, Simard MN, Shah V, Shah PS, Kelly E, For the Canadian Neonatal Network and the Canadian Neonatal Follow-Up Network Investigators. Neurodevelopmental outcomes following bevacizumab for retinopathy of prematurity. (Trainee Publication, Neonatal Resident) Pediatrics. 2016 Apr;137(4).

Morency AM, Shah PS, Whittle W, Seaward G, Murphy K. Obstetrical and neonatal outcomes of triplet births – spontaneous vs. assisted reproductive technology conception. J Matern Fetal Neonatal Med. 2016 Mar;29(6):938-43.

Mukerji A, Diambomba Y, Lee SK, Jain A. Use of Targeted Neonatal Echocardiography and Focused Cardiac Ultrasound in Neonatal Intensive Care Units: Time to Embrace it? J Ultrasound Med. 2016 Jul;35(7):1579-91.

O’Connor DL, Gibbins S, Kiss A, Bando N, Brennan-Donnan J, Ng E, Campbell DM, Vaz S, Fusch C, Asztalos E, Church P, Kelly E, Ly L, Daneman A, Unger S. Effect of supplemental donor human milk compared with preterm formula on neurodevelopment of very low-birth-weight infants at 18 months: A randomized clinical trial. JAMA. 2016 Nov 8; 316(18):1897-1905.

Ohlsson A, Shah PS. Paracetamol (acetaminophen) for prevention or treatment of pain in newborns. Cochrane Database Syst Rev. 2016 Oct 7;10:CD011219.

Oliver F, Bertelle V, Shah PS, Drolet C, Piedboeuf B on behalf of the Canadian Neonatal Network Investigators. Association between birth route and late-onset sepsis in very preterm neonates. J Perinatol. 2016 Dec;36(12):1083-1087.

Panczuk JK, Unger S, Francis J, Bando N, Kiss A, O’Connor DL. Introduction of bovine based nutrient fortifier and gastrointestinal inflammation in VLBW infants as measured by fecal calprotection. Breastfeed Med. 2016 Jan-Feb;11(1):2-5.

Resende N, Moore K, Nicholls D, Ting J, Jain A, McNamara P. The Impact of a Dedicated Patent Ductus Arteriosus Ligation Team on Neonatal Health Care Outcomes. J Perinatol. 2016 Jun;36(6):463-8.

Schmidt B, Whyte R, Shah PS, Abbasi S, Bairam A, Harrold J, Roberts R. Effects of Targeting Higher or Lower Oxygen Saturations in Centers with More vs Less Separation Between Median Saturations in the Two Groups of the Canadian Oxygen Trial. J Pediatr. 2016 Nov;178:288-291.e2.

Sgro M, Kandasamy S, Shah V, Ofner M, Campbell D. Severe neonatal hyperbilirubinemia decreased after the 2007 Canadian Guidelines. J Pediat 2016;171:43-7.

Shah PS, Lui K, Sjörs G, Mirea L, Reichman B, Adams M, Modi N, Darlow BA, Kusuda S, San Feliciano L, Yang J, Håkansson S, Mori R, Bassler D, Figueras-Aloy J, Lee SK, for the investigators of the International Network for Evaluating Outcomes (iNeo) of Neonates. Neonatal outcomes of very low birth weight and very preterm neonates: an international comparative study. J Pediatr. 2016 Oct;177:144-152.e6.

Smith RW, Mohamed A, Young J, Jefferies A, Shah V. Factors associated with car seat test failure in late preterm infants: A retrospective chart review. Paediatr Child Health 2016; 21(1):16-20.

Soraisham AS, Harabor A, Shivananda S, Ye XY, Alvaro R, Lee SK, Shah PS, Canadian Neonatal Network. Trends and variations in inhaled nitric oxide use in preterm infants in Canadian Neonatal Intensive Care Units: A retrospective cohort study. Am J Perinatol. 2016 Jun;33(7):715-22.

Srinath BK, Shah J, Kumar P, Shah PS. Kangaroo care by fathers and mothers: Comparison of physiological and stress responses in preterm infants. J Perinatol 2016 May;36(5):401-4.

Stevens B, Yamada J, Promislow S, Barwick M, Pinard M, CIHR Team in Children’s Pain Sustainability of pediatric pain outcomes following a knowledge translation booster intervention. Pediatrics. 2016 Oct;138(4).

Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK. Corticosteroids compared to intravenous immune globulin for the treatment of immune thrombocytopenia in pregnancy. Blood. 2016 Sep 8;128(10):1329-35.

Synnes A, Luu TM, Moddemann D, Church P, Lee D, Vincer M, Ballantyne M, Majnemer A, Creighton D, Yang JM, Sauve R, Saigal S, Shah P, Lee SK, Canadian Neonatal Follow-Up Network. Determinants of Developmental Outcomes in a Very Preterm Canadian Cohort. Arch Dis Child Fetal Neonatal Ed. 2017 May;102(3):F235-F234.

Ting J, Resende M, Moore K, Nicholls D, Weisz D, El-Khuffash A, Jain A, McNamara P. Predictors of Respiratory Instability in Neonates after the Introduction of Targeted Milrinone Treatment. J Thorac Cardiovasc Surg. 2016 Aug;152(2):498-504.

Ting JY, Synnes A, Roberts A, Deshpandey A, Dow K, Yoon E, Lee KS, Dobson S, Lee SK, Shah PS for the Canadian Neonatal Network Investigators. Association of antibiotic utilization and neonatal outcomes in


very-low-birth-weight infants without proven sepsis. JAMA Pediatr. 2016 Dec 1;170(12):1181-1187.

Vidler M, Magee LA, von Dadelszen P, Reym E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Singer J, Gafni A, Gruslin A, Helewa M, Hutton E, Lee SK, Lee T, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM, CHIPS Study Group. Women’s views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). Eur J Obstetr Gynecol Reprod Biol 2016;206:105–113.

Wallis CJD, Mahar AL, Choo R, Herschorn S, Kodama RT, Shah PS, Danjoux C, Narod SA, Nam RK. Secondary malignancies following radiotherapy for prostate cancer: A systematic review and meta-analysis. BMJ. 2016 Mar 2;352:i851.

Wallis CJD, Saskin R, Choo R, Herschorn S, Kodama RT, Satkunasivam R, Shah PS, Danjoux C, Nam RK. Surgery versus radiotherapy for clinically-localized prostate cancer: a systematic review and meta-analysis. Eur Urol. 2016 Jul;70(1):21-30.

Weisz D, Martins F, Nield L, El-Khuffash A, Jain A, McNamara P. Acetaminophen to avoid surgical ligation in extremely low gestational age neonates with hemodynamically significant patent ductus arteriosus. J Perinatol. 2016 Aug;36(8):649-53.

Wong M, Kantores C, Ivanovska J, Jain A, and Jankov R. Simvastatin Prevents and Reverses Chronic Pulmonary Hypertension in Newborn Rats via Pleiotropic Inhibition of RhoA Signaling. Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L985-L999.

Zhu MY; Milligan N; Keating S; Windrim R; Keunen J; Thakur V; Ohman A; Portnoy S; Sled JG; Kelly E; Yoo SJ; Gross-Wortmann L; Jaeggi E; Macgowan CK; Kingdom JC; Seed M. The hemodynamics of late-onset intrauterine growth restriction by MRI. American Journal of Obstetrics and Gynecology 2016;367:e1-17.

2015Ahmed M, Mohamed A, Aziz K, Shivananda S, Yoon E, Shah PS on behalf of the Canadian Neonatal Network. Peripherally inserted central catheter (PICC) versus umbilical venous catheter as primary access in very preterm neonates. Pediatrics. 2015 Dec;136(6):1073-9.

Al Wassia H, Shah PS. Cord milking and health outcomes: A systematic review and Meta-analysis. JAMA Pediatr 169(1):18-25, Jan 2015.

Almidani E, Jefferies A, Khadawardi E, Shah V. Evaluating Twins at Risk for Sepsis: The dilemma of the well-appearing co-twin. J Clin Neonatol 2015;4(3):164-8.

Amin M, Nouri R, El Salhy M, Shah PS, Azarpazhooh A. Caries Recurrence after Treatment under General Anesthesia for Early Childhood Caries: A Retrospective Cohort Study. Eur Arch Paediatr Dent. 2015 Aug;16(4):325-31.

Anabrees J, Shah VS, AlOsaimi A, AlFaleh K. Glycerin laxatives for prevention or treatment of feeding intolerance in very low birth weight infants. Cochrane Database Syst Rev. 2015 Sep 30;(9):CD010464.

Bhatia A, Flamer D, Shah PS. Perineural steroids for trauma and compression-related chronic peripheral neuropathic pain: A systematic review and meta-analysis. Can J Anaesth 62(6):650-662, Jun 2015.

Birnie KA, Chambers CT, Taddio A, McMurtry CM, Noel M, Pillai Riddell R, Shah V, HELPinKids&Adults Team. Psychological Interventions for Vaccine Injections in Children and Adolescents: Systematic Review of Randomized and Quasi-Randomized Controlled Trials. Clin J Pain. 2015 Oct 31:S72-89.

Boerner KE, Birnie KA, Chambers CT, Taddio A, McMurtry CM, Noel M, Shah V, Pillai Riddell R; HELPinKids&Adults Team. Simple Psychological interventions for

reducing pain from common needle procedures in adults: Systematic review of randomized and quasi-randomized controlled trials. Clin J Pain 2015;10:S90-8.

Chiarelli L, Mirea L, Yang JM, Lee SK, Shah PS, Canadian Neonatal Network. Neonatal Outcomes in Very Preterm Infants Conceived Using Assisted Reproductive Technologies. Am J Perinatol. 2015 May;32(6):515-22.

D’Souza R, Shah PS. Predicting stillbirth: still a distant reality. BJOG;122(1):56, Jan 2015.

Deb-Rinker P, León JA, Gilbert N, Rouleau J, Shah PS, Sauve R, Kramer M, Joseph KS, for the Canadian Perinatal Surveillance System (Public Health Agency of Canada). Differences in birth registration and perinatal and infant mortality rates in selected high-income countries. BMC Pediatrics;15:112, Sep 2015.

Gibbins S, Stevens B, Dionne K, Yamada J, Pillai Riddell R, McGrath P, Asztalos E, O’Brien K, Beyene J, McNamara P, Johnson C. Perceptions of health professionals on pain in extremely low gestational age infants. Qual Health Res 2015; 25(6):763-74.

Han S, Yu Z, Chen C, Wang J, Liu L, Wei Q, Jiang C, Guo J, Li M, Yang J, Shah PS, Chen C on behalf of the Chinese Multicenter study Coordination Group for Neonatal Hyperbilirubinemia. A model for predicting significant hyperbilirubinemia in Chinese neonates.Pediatrics;136(4):e896-905.

Hei M, Lee SK, Shah PS, Jain A for the Canadian Neonatal Network. Outcomes for symmetrical and asymmetrical small for gestational age infants in Canadian Tertiary NICUs. Am J Perinatol;32(8):725-32, Jul 2015.

Hellmann J, Knighton R, Lee SK, Shah PS; Canadian Neonatal Network End of Life Study Group. Neonatal deaths: prospective

7510-Year Report

exploration of the causes and process of end-of-life decisions. Arch Dis Child Fetal Neonatal Ed. 2016 Mar;101(2):F102-7.

Hossain S, Shah PS, Ye XY, Darlow BA, Lee SK, Kei L, Canadian Neonatal Network, Australia New Zealand Neonatal Network. Outcome comparison of very preterm infants cared for in the neonatal intensive care units in Australia and New Zealand and in Canada. J Paediatr Child Health. 2015 Sep;51(9):881-8.

Isayama T, Mirea L, Mori R, Kusuda S, Fujimura M, Lee SK, Shah PS and the Neonatal Research Network of Japan and the Canadian Neonatal Network. Patent Ductus Arteriosus Management and Outcomes in Japan and Canada: Comparison of Proactive and Selective Approaches. Am J Perinatol. 2015 Sep;32(11):1087-94.

Isayama T, Shah PS, Ye XY, Dunn MS, DaSilva O, Alvaro R, Lee KS and the Canadian Neonatal Network. Adverse Impact of Maternal Cigarette Smoking on Preterm Infants: A Population-Based Cohort Study. Am J Perinatol. 2015 Oct;32(12):1105-11.

Jain A, McNamara P. Persistent Pulmonary Hypertension of the Newborn – Advances in Diagnosis and Treatment. Semin Fetal Neonatal Med. 2015 Apr 2. Pii: S1744-165X(15)00037-2.

Jain A, Shah P. Diagnosis, Evaluation and Management of Patent Ductus Arteriosus in Preterm Neonates. JAMA Pediatr. 2015 Sep 1;169(9):863-72.

Jantzen C, Lodha A, Mirea L, Lee SK, Ye XY, Sankaran K. Effects of nosocomial infection trends on neonatal outcomes in preterm infants <33 weeks of gestational age in Canadian NICUs. Chin J Contemp Pediatr, 2015, 17(10): 1019-1027.

Jeejeebhoy FM, Zelop CM, Lipman S, Carvalho B, Joglar J, Mhyre JM, Katz VL, Lapinsky SE, Einav

S, Warnes CA, Page RL, Griffin RE, Jain A, Dainty KN, Arafeh J, Windrim R, Koren G, Callaway CW. Cardiac Arrest in Pregnancy: A Scientific Statement From the American Heart Association. Circulation. 2015 Oct 6. pii: CIR.0000000000000300.

Jiang SY, Lv YY , Ye XY, Monterrosa L, Shah PS, Lee SK, Canadian Neonatal Network. Intensity of delivery room resuscitation and neonatal outcomes for infants born at 33 to -36 weeks’ gestational age. J Perinatol. 2016 Feb;36(2):100-5.

Keir A, Aziz K, McMillan D, Monterossa L, Ojah C, Lee SK, Shah PS and the Canadian Neonatal Network. Red Blood Cell Transfusions at 21 Days of Age or Older in Previously Transfusion-Naive Very Preterm Infants: Association with Neonatal Outcomes. Am J Perinatol. 2015 Oct;32(12):1139-44.

Keir A, Yang J, Harrison A, Pelausa E, Shah PS and the Canadian Neonatal Network. Temporal changes in blood product usage in preterm neonates born at <30 weeks gestation in Canada. Transfusion. 2015 Jun;55(6):1340-6.

Kirtsman M, Yoon E, Ojha C, Cieslak Z, Lee SK, Shah PS and the Canadian Neonatal Network. Nil-per-os days and necrotizing enterocolitis in extremely preterm infants. Am J Perinatol;32(8):785-94, Jul 2015.

Lavoie P, Stritzke A, Ting J, Jabr M, Jain A, Kwan E, Chakkarapani E, Brooks P, Brant R, McNamara P, Holsti L. A Randomized Controlled Trial of the Use of Oral Glucose With or Without Gentle Facilitated Tucking of Infants during Neonatal Echocardiography. PLoS One. 2015 Oct 23;10(10):e0141015.

Lavoie P, Stritzke A, Ting J, Jabr M, Jain A, Kwan E, Chakkarapani E, Brooks P, Brant R, McNamara P, Holsti L. Oral Glucose during Targeted Neonatal Echocardiography: Is It useful? Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F374-5.

Lee SK, Aziz K, Singhal N, Cronin CM, Canadian Neonatal Network Partnerships for Health System Improvement (PHSI) Study Group. An Evidence-based Practice for Improving Quality (EPIQ) program has greater impact on improvement of outcomes than the use of clinical practice guidelines in neonatal intensive care units. Paediatr Child Health 2015; 20(1):e1-9.

Lodha A, Seshia MM, McMillan D, Barrington K, Yang J, Lee SK, Shah PS and the Canadian Neonatal Network. Association of early caffeine administration and neonatal outcomes in very preterm neonates. JAMA Pediatr. 2015 Jan;169(1):33-8.

Lyu Y, Shah PS, Ye XY, Warre R, Piedboeuf B, Deshpandey A, Dunn M, Lee SK; Canadian Neonatal Network. Association between admission temperature and mortality and major morbidity in preterm infants born at fewer than 33 weeks’ gestation. JAMA Pediatr. 2015 Apr;169(4):e150277.

Lyu YY, Mirea L, Yang JM, Warre R, Zhang J, Lee SK, Li Z. Secular trends in age at menarche among Chinese women born from 1955 to 1985. BMC Womens Health. 2014 Dec 12;14:155.

Lyu YY, Shah PS, Ye XY, Warre R, Piedboeuf B, Deshpandey A, Dunn M, Lee SK, Canadian Neonatal Network. Impact of Admission Temperature on Mortality and Major Morbidity in Very Preterm Infants. Jama Pediatr 2015;169(4):e150277.

MacDonell K, Omrin D, Pitlyk K, Pezzullo S, Diambomba Y An Effective Communication Initiative: Using parents’ experience to improve delivery of difficult news in the NICU. Journal of Neonatal Nursing 2015:21(4): 142–149.

Magee LA, von Dadelszen P, Rey E, Ross S, Asztalos E, Murphy K, Menzies JM, Sanchez J, Singer J, Gafni A, Gruslin A, Helewa M, Hutton E, Lee SK, Logan AG, Ganzevoort W, Welch R, Thornton JG, Moutquin JM, and CHIPS Study Group. The CHIPS Trial (Control of


Hypertension In Pregnancy Study). NEJM 01/2015; 372(5):407-17.

Magee LA, von Dadelszen P, Singer J, Lee T, Rey E, Ross S, Asztalos E, Murphy KE, Menzies J, Sanchez J, Gafni A, Gruslin A, Helewa M, Hutton E, Koren G, Lee SK, Logan AG, Ganzevoort JW, Welch R, Thornton JG, Moutquins JM. Do labetalol and methyldopa have different effects on pregnancy outcome? Analysis of data from the Control of Hypertension In Pregnancy Study (CHIPS) trial. BJOG. 2016 Jun;123(7):1143-51.

Mahl S, Lee S, Baker GR, Cronin CM, Stevens B, Ye XY. The Association of Organizational Culture and Quality Improvement Implementation with Neonatal Outcomes in the NICU. J Pediatr Health Care. 2015 Sep-Oct;29(5):435-41.

Malinowski A, Shehata N, DeSouza R, Ward R, Shah PS, Murphy KE. Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis. Blood. 2015 Nov 19;126(21):2424-35; quiz 2437.

McMurtry CM, Noel M, Taddio A, Antony MM, Asmundson GJ, Riddell RP, Chambers CT, Shah V; HELPinKids&Adults Team. Interventions for individuals with high levels of needle fear: Systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 2015;10:S109-23.

McMurtry CM, Pillai Riddell R, Taddio A, Racine N, Asmundson GJ, Noel M, Chambers CT, Shah V; HELPinKids&Adults Team. Far from “Just a Poke”: Common painful needle procedures and the development of needle fear. Clin J Pain 2015;10:S3-11.

Melamed N, Shah J, Soraisham A, Yoon EW, Lee SK, Shah PS, Murphy K. Association between Antenatal Corticosteroid Administration to Birth Interval and Outcomes of Preterm Neonates. Obstet Gynecol. 2015 Jun;125(6):1377-84.

Melamed N, Whittle W, Kelly EN, Windrim R, Seaward PGR, Keunen J, Keating S, Ryan G: Fetal thrombocytopenia in pregnancies with fetal human parvovirus-B19 infection. Amer J Obstet Gynecol 2015; 212(6):793.e1-8.

Mohd S, Mohd A, Ng E, Aziz A, Lee SK, Shah P. Peripherally inserted central versus umbilical catheters as primary access in preterm neonates. Pediatrics. 2015 Dec;136(6):1073-9.

Monks DT, Hoppe DW, Downey K, Shah V, Bernstein P, Carvalho JC. A perioperative course of gabapentin does not produce a clinically meaningful improvement in analgesia after cesarean delivery: A randomized controlled trial. Anesthesiology 2015;123(2):320-6.

Mukerji A, Shah V, Shah PS. Periventricular/intraventricular hemorrhage and neurodevelopmental outcomes: A meta-analysis. Pediatrics. 2015 Dec;136(6):1132-43.

Mukerji A, Shah V, Shah PS. Periventricular/intraventricular hemorrhage and neurodevelopmental outcomes: A meta-analysis. Pediatrics. 2015 Dec;136(6):1132-43.

Mumtaz K, Faisal N, Husain S, Morillo A, Renner E, Shah PS. Universal prophylaxis or pre-emptive strategy for cytomegalovirus disease after liver transplantation: A systematic review and meta-analysis. Am J Transplant. 2015 Feb;15(2):472-81.

Ng DV, Brennan-Donnan J, Unger S, Bando N, Gibbins S, Nash A, Kiss A, O’Connor DL. How close are we to achieving energy and nutrient goals for VLBW infants in the first week? JPEN J Parenter Enteral Nutr. 2017 Mar;41(3):500-506.

Nir M, Shah J, Soraisham A, Yoon EW, Lee SK, Shah PS, Murphy KE, Canadian Neonatal Network. Association between Antenatal Corticosteroid Administration to Birth Interval and Outcomes of Very Preterm Neonates. Obstet Gynecol. 2015 Jun;125(6):1377-84.

Noel M, Taddio A, McMurtry CM, Chambers CT, Pillai Riddell R, Shah V; HELPinKids&Adults Team. HELPinKids&Adults Knowledge Synthesis of the management of vaccination pain and high levels of needle fear: Limitations of the evidence and recommendations for future research. Clin J Pain 2015;10:S124-31.

O’Brien K, Bracht M, Robson K, Ye X, Mirea L, Cruz M, Ng E, Monterrosa L, Soraisham A, Alvaro R, Narvey M, Da Silva O, Kei L, Tarnow-Mordi W, Lee S. Evaluation of the Family Integrated Care model of neonatal intensive care: a cluster randomized controlled trial in Canada and Australia. BMC Pediatrics 2015, 15:210.

O’Connor DL, Ewaschuk J, Unger S. Human milk pasteurization: benefits and risks. Cur Opin Clin Nutri 2015 May; 18 (3): 269-75.

Ohlsson A, Shah PS. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm and/or low-birth-weight infants. Cochrane Database Syst Rev. Mar 2015 11;3:CD010061.

Ohlsson A, Shah PS. Paracetamol (acetaminophen) for prevention or treatment of pain in newborns. Cochrane Database Syst Rev. 2016 Oct 7;10:CD011219.

Pillai Riddell R, Taddio A, McMurtry CM, Chambers C, Shah V, Noel M; HELPinKIDS Team. Psychological interventions for vaccine injections in young children 0 to 3 years: Systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 2015;10:S64-71.

Pillai Riddell R, Taddio A, McMurtry CM, Shah V, Noel M, Chambers CT; HELPinKIDS&Adults Team. Process interventions for vaccine injections: Systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 2015;10:S99-108.

Poets CF, Roberts RS, Schmidt B, Whyte RK, Asztalos EV, Bader

7710-Year Report

D, Bairam A, Moddemann D, Peliowski A, Rabi Y, Solimano A, Nelson H, for the Canadian Oxygen Trial Investigators. Association between intermittent hypoxemia or bradycardia and late death or disability in extremely preterm infants. JAMA. 2015 Aug 11;314(6):595-603.

Rabi Y, Lodha A, Soraisham A, Singhal N, Barrington K, Shah PS and the Canadian Neonatal Network. Outcomes of preterm infants following introduction of room air resuscitation. Resuscitation. 2015 Nov;96:252-9.

Rolnitsky A, Lee SK, Piedbouf B, Harrison A, Shah PS, on behalf of the Canadian Neonatal Network. Prophylactic interventions in neonatology: How do they fare in real life? Am J Perinatol. 2015 Oct;32(12):1098-104.

Roth DE, Gernand AE, Morris SK, Pezzack B, Manirul Islam M, Dimitris MC, Shahnta SS, Zlotkin SH, Willan AR, Ahmed T, Shah PS, Murphy KE, Weksberg R, Choufani S, Shah R, Al Hamud A. Maternal vitamin D supplementation during pregnancy to promote infant growth in Dhaka, Bangladesh (MDIG trial)” Study protocol for a randomized controlled trial. Trials;16:300, Jul 2015.

Sahgal A, Aoyama H, Kocher M, Neupane B, Collette S, Tago M, Shah PS, Beyene J, Chang EL. Phase III Trials of stereotactic radiosurgery with or without whole brain radiotherapy for 1-4 brain metastases: Individual patient data meta-Analysis. Int J Radiat Oncol Biol Phys 15;91(4):710-717, Mar 2015.

Shah J, Jefferies A, Yoon E, Lee SK, Shah PS and the Canadian Neonatal Network. Risk Factors and Outcomes of Late-Onset Bacterial Sepsis in Preterm Neonates Born at <32 Weeks’ Gestation. Am J Perinatol;32(7):675-82, Jun 2015.

Shah J, Shah PS, Jefferies A. Hematological parameters immediately after birth in twins and higher order multiples. Am J Perinatol;32(7):653-8, Jun 2015.

Shah J, Singhal N, Silva OD, Rouvinez-Bouali N, Seshia M, Lee SK, Shah PS, Canadian Neonatal Network. Intestinal perforation in very preterm neonates: risk factors and outcomes. J Perinatol. 2015 Aug;35(8):595-600.

Shah P, Mirea L, Ng E, Solimano A, Lee SK, Canadian Neonatal Network. Association of unit size, resource utilization and occupancy with outcomes of preterm infants. J Perinatol. 2015 Jul;35(7):522-9.

Shah PS, Mirea L, Ng E, Solimano A, Lee S on behalf of the Canadian Neonatal Network. Association of unit size, resource utilization, and occupancy with outcomes of preterm infants. J Perinatol. 2015 Jul;35(7):522-9.

Shah V, Taddio A, McMurtry CM, Halperin SA, Noel M, Pillai Riddell R, Chambers CT; HELPinKIDS Team. Pharmacological and combined interventions to reduce vaccine injection pain in children and adults: Systematic review and meta-analysis. Clin J Pain 2015;10:S38-63.

Shalabi M, Adel Mohamed, Yoon E, Aziz K, Lee S, Shah PS; Canadian Neonatal Network. Risk of Infection Using Peripherally Inserted Central and Umbilical Catheters in Preterm Neonates. Pediatrics 2015, 136(6):1073-9.

Shifrin Y, Sadeghi S, Pan J, Jain A, Fajardo AF, McNamara P, Belik J. Maternal-pup Interaction Disturbances Induce Long Lasting Changes in the Newborn Rat Pulmonary Vasculature. Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1186-98.

Silver SA, Shah PS, Chertow G, Harel S, Wald R Harel Z. Risk Prediction Models for Contrast Induced Nephropathy: A Systematic Review. BMJ. 2015 Aug 27;351:h4395.

Taddio A, McMurtry CM, Shah V, Riddell RP, Chambers CT, Noel M, MacDonald NE, Rogers J, Bucci LM, Mousmanis P, Lang E,

Halperin SA, Bowles S, Halpert C, Ipp M, Asmundson GJ, Rieder MJ, Robson K, Uleryk E, Antony MM, Dubey V, Hanrahan A, Lockett D, Scott J, Votta Bleeker E; HELPinKids&Adults. Reducing pain during vaccine injections: Clinical practice guideline. CMAJ 2015;187:975-82.

Taddio A, McMurtry CM, Shah V, Yoon EW, Uleryk E, Pillai Riddell R, Lang E, Chambers CT, Noel M, MacDonald NE; HELPinKids&Adults Team; Methodology for knowledge synthesis of the management of vaccination pain and needle fear. Clin J Pain 2015;10:S12-9.

Taddio A, Parikh C, Yoon EW, Sgro M, Singh H, Habtom E, Ilersich AF, Pillai Riddell R, Shah V. Impact of parent-directed education on parental use of pain treatments during routine infant vaccinations: a cluster randomized trial. Pain 2015;156:185-91.

Taddio A, Shah V, McMurtry CM, MacDonald NE, Ipp M, Riddell RP, Noel M, Chambers CT; HELPinKids&Adults Team. Procedural and physical interventions for vaccine injections: Systematic review of randomized controlled trials and quasi-randomized controlled trials. Clin J Pain 2015;10:S20-37.

Taddio A, Shah V, Wang J, Parikh C, Smart S, Ipp M, Riddell RP, Franck LS. Usability and knowledge testing of educational tools about infant vaccination pain management directed to postnatal nurses. BMC Med Educ 2015;15:45.

Thomas KE, Shah PS, Canning R, Harrison A, Lee SK, Dow KE for Canadian Neonatal Network. Retinopathy of prematurity: Risk factors and variability between Canadian NICUs. J Neonatal Perinatal Med. 2015;8(3):207-14.

Unger S, Stintzi A, Shah P, Mack D, O’Connor DL. Gut microbiota of the very-low-birth-weight infant. Pediatr Res 2015 Jan;77(1-2):205-213.

Weisz DE, Shivananda S,


Asztalos E, Shah PS, Lee SK. Intrapartum magnesium sulphate and need for intensive delivery room resuscitation. Arch Dis Child Fetal Neonatal Ed. 2015 Jan;100(1):F59-65.

Wong J, Shah PS, Yoon EW, Yee W, Lee S, Dow K. Inotrope use among extremely preterm infants in Canadian neonatal intensive care units: variation and outcomes. Am J Perinatol. 2015 Jan;32(1):9-14.

Zhou Q, Lee SK, Hu XJ, Jiang SY, Chen C, Wang CQ, Cao Y. Successful reduction in central line-associated bloodstream infections in a Chinese neonatal intensive care unit. Am J Infect Control. 2015 Mar 1;43(3):275-9.

2014Alali A, McCredie V, Golan E, Shah PS, Nathens A. Beta blockers for acute traumatic brain injury: A systematic review and meta-analysis. Neurocrit Care. 2014 Jun;20(3):514-23.

Ali A, Kumar VNC, Shah PS, Warner E, Beyene J, Dent R, Simmons C. Aromatase Inhibitors for the adjuvant treatment of breast cancer in postmenopausal women. Cochrane Database of Systematic Reviews. Issue 6; Art. No: CD011133. Jun 2014.

Asztalos EV, Murphy KE, Andrew R. Willan AR, Matthews SG, Ohlsson A, Saigal SJ, Armson BA, Kelly EN, Delisle MF, Gafni A, Lee SK, Sananes, R, Rovet J, Guselle P, Amankwah K, Saleem M, Sanchez J, for the MACS-5 Collaborative Group. Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study at 5 years of age (MACS-5). BMC Pregnancy Childbirth. 2014; 14: 272-9.

Avila ML, Shah PS, Brandão LR. Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac catheterization. Cochrane

Database Syst Rev. 2014 Mar 4;(3):CD010196.

Barton, M, O’Brien, K, Robinson, J, Davies, D, Robinson, J, Simpson, K, Asztalos, E, Langley, J, Le Saux, N, Reginald, S, Synnes, A, Ben, T, Earl, R, Chuck, H, Lajos, K, Richardson, S. Invasive Candidiasis in Very Low Birth Weight Preterm Infants: Risk and Outcome in a Prospective Multicenter Study of Cases and their Matched Controls. BMC Infectious Diseases. 2014 Jun 12;14:327.

Basil K, Yasseen AS, Walker M, Sgro MD, Shah PS, Campbell DM, Mamdani M, Sprague AE, Lee SK, McGuire JL. The Association between Obstetrical Interventions and Late Preterm Birth. Am J Obstet Gynecol. 2014 Jun;210(6):538.e1-9.

Bassil KL, Shah PS, Shah V, Ye XY, Lee SK, Jefferies AL and the Canadian Neonatal Network. Impact of late preterm and early term infants on Canadian neonatal intensive care units. Am J Perinatol 2014;4:269-78.

Brandão LR, Shah N, Shah PS. Low molecular weight heparin for prevention of central venous catheterization-related thrombosis in children. Cochrane Database Syst Rev. 2014 Mar 10;(3):CD005982.

Clyman R, Wickremasinghe A, Merritt TA, Solomon T, McNamara P, Jain A, Singh J, Chu A, Noori S, Sekar K, Pascal M. Lavoie, Joshua T. Attridge, Swanson J, Gillam-Krakauer M, Reese J, DeMauro S, Poindexter B, Aucott S, Satpute M, Fernandez E, Auchus R, and PDA Ligation/Hypotension Trial Investigators. Hypotension Following Patent Ductus Arteriosus Ligation: The Role of Adrenal Hormones. J Pediatr. 2014 Jun;164(6):1449-55.

Critch J, Unger S, Nutrition and Gastroenterology Committee, Canadian Paediatric Society. Nutrition for healthy term infants, six to 24 months: An overview. Paediatr Child Health. 2014 Dec;19(10):547-52.

Dar S, Lazer T, Shah PS, Librach CL. Neonatal outcomes after blastocyst versus cleavage stage embryo transfer among singleton births: A systematic review and meta-analysis. Hum Reprod Update. 2014 May-Jun;20(3):439-48.

Doyle LW, Schmidt B, Anderson PJ, Davis PG, Moddemann D, Grunau RE, O’Brien K, Sankaran K, Herlenius E, Roberts R; Reduction in developmental coordination disorder with neonatal caffeine therapy. Caffeine for Apnea of Prematurity Trial investigators. J Pediatr. 2014 Aug;165(2):356-359.e2.

Dunlop K, Gosal K, Kantores C, Ivanovska J, Dhaliwal R, Desjardins JF, Connelly K, Jain A, McNamara P, Jankov R. Therapeutic Hypercapnia Prevents Inhaled Nitric Oxide-induced Right Ventricular Systolic Dysfunction in Juvenile Rats. Free Radic Biol Med. 2014;69:35-49.

Duong HH, Mirea L, Shah PS, Yang J, Lee SK, Sankaran K and the Canadian Neonatal Network. Retrospective analyses of pneumothorax in neonates: Trends predictors and outcomes. J Neonatal Perinatal Med. 2014;7(1):29-38.

El-Khuffash A, Jain A, Corcoran D, Shah P, Hooper C, Brown N, Poole S, Shelton E, Milne G, Reese J, McNamara P. Efficacy of Paracetamol on Patent Ductus Arteriosus Closure may be Dose Dependent: Evidence from human and murine studies. Pediatr Res. 2014 Sep;76(3):238-44.

EL-Khuffash A, Jain A, Weisz D, Mertens L, McNamara P. Assessment and Treatment of Post Patent Ductus Arteriosus Ligation Syndrome. J Pediatr. 2014 Jul;165(1):46-52.

Enomoto M, Jain A, Pan J, Shifrin Y, Vliet TV, McNamara P, Jankov R, Belik J. Newborn Rat Response to Single Versus Combined cGMP-Dependent Pulmonary Vasodilators. Am J Physiol Lung Cell Mol Physiol. 2014;306(2):L207-15.

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Esquinas AM, Shah PS. Noninvasive mechanical ventilation and mechanical insufflator: A definitive solid combination? Some key methodology considerations. Pediatr Pulmonol. 2014 Oct;49(10):1043-4.

Finan E, Sehgal A, ElKhuffash A, McNamara PJ. Targeted Neonatal Echocardiography Services: Need for Standardised Training and Quality Assurance. J Ultrasound Med. 2014 Oct;33(10):1833-41.

Gosal K, Dunlop K, Dhaliwal R, Ivanovska J, Kantores C, Desjardins JF, Connelly K, McNamara P, Jain A, Jankov R. Rho-kinase Mediates Right Ventricular Systolic Dysfunction in Rats with Chronic Neonatal Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2015 Jun;52(6):717-27.

Harel Z, Sholzberg M, Pavenski K, Harel S, Wald R, Bell CR, Shah PS, Perl J. Comparisons between novel oral anticoagulants and vitamin K antagonists in patients with CKD. J Am Soc Nephrol. 2014 Mar;25(3):431-42.

Hei MY, Lee S, Shah P, Jain A. Outcomes for symmetrical and asymmetrical small for gestational age preterm infants in Canadian tertiary NICUs. Am J Perinatol. 2015 Jul;32(8):725-32.

Hogan ME, Smart S, Shah V, Taddio A. A systematic review of vapocoolants for reducing pain from venipuncture and venous cannulation in children and adults. J Emerg Med 2014;47(6):736-49.

Jain A, Mohamed A, El-Khuffash A, Connelly K, Dallaire F, Jankov R, McNamara P, Mertens L. A Comprehensive Echocardiographic Protocol for Assessing Neonatal Right Ventricular Dimensions and Function in the Transitional Period: Normative Data And Z-scores. J Am Soc Echocardiogr. 2014 Dec; 27(12):1293-304.

James A, Corcoran J, Jain A, McNamara P, Mertens L, Franklin O, EL-Khuffash A. Assessment of

Myocardial Performance in Preterm Infants less than 29 Weeks Gestation during the Transitional Period. Early Hum Dev. 2014 Dec;90(12):829-35.

Jiang SY, Warre R, Qiu XM. O’Brien K, Lee SK. Parents as practitioners in preterm care. Early Hum Dev. 2014 Nov;90(11):781-5.

Kassirer Y, O’Connor D, Rutherford E, Rolnitzky A, Unger S. Implications for Orthodox Jewish families in the provision of mother’s own and donor milk for their very low birthweight infant. J Hum Lact 2014 Nov;30(4):402-4.

Kelly EN, Sananes R, Chiu-Man C, Silverman ED, Jaeggi E: Prenatal anti-ro antibody exposure, congenital complete atrio-ventricular heart block, and high-dose steroid therapy: Impact on neurocognitive outcome at school-age. Arthritis Rheumatol. 2014 66(8):2290-6.

Kirtsman M, Yoon E, Ojah C, Cieslak Z, Lee SK, Shah PS, Canadian Neonatal Network. Nil-per-os days and necrotizing enterocolitis in extremely preterm infants. Am J Perinatol. 2015 Jul;32(8):785-94.

Lee SK, Shah P, Singhal N, Aziz K, Synnes A, McMillan DD, Seshia M, Canadian Neonatal Network EPIQ Study Group. Association of a quality improvement program with neonatal outcomes in extremely preterm infants: A prospective cohort study. CMAJ. 2014 Sep 16;186(13):E485-94.

Lee SK. O’Brien K. Innovation: Parents as primary care-givers for their infants in the neonatal intensive care unit. CMAJ. 2014 Aug 5;186(11):845-7.

Lega I, Margel D, Beyene J, Shah PS, Rochon PA, Lipscombe LL. The effect of metformin on mortality following cancer among patients with diabetes. Cancer Epidemiol Biomarkers Prev. 2014 Oct;23(10):1974-84.

Leibel S, Vachharajani A. Needle Aspiration of the Pneumothorax. Neoreviews 2014; 15:e163-e165.

Lin S, Callaway CW, Shah PS, Wagner JD, Beyene J, Morrison LJ. Epinephrine for out-of-hospital cardiac arrest resuscitation: a systematic review and meta-analyses. Resuscitation. 2014 Jun;85(6):732-40.

Lodha A, Seshia M, McMillan DD, Barrington K, Lee SK, Shah PS. Association of early caffeine administration and neonatal outcomes in very preterm infants. JAMA Pediatr. 2015 Jan;169(1):33-8.

Louis D, More K, Oberoi S, Shah PS. Intravenous Immunoglobulin in Isoimmune Hemolytic Disease of Newborns: An Updated Systematic Review and Meta-analysis. Arch Dis Child Fetal Neonatal Ed. 2014 Jul;99(4):F325-31.

Melamed N, Ray JG, Shah PS, Berger H, Kingdom J. Should we use customized fetal growth percentiles in urban Canada? J Obstet Gynaecol Can. 2014 Feb;36(2):164-170.

Mestre TA, Shah PS, Marras C, Lang A. The other face of placebo: the lessebo effect in Parkinson’s disease. Meta-analyses. Neurology 82:1402-9, Apr 2014.

Mohamed A, Nasef N, Shah V, McNamara P. Vasopressin as a rescue therapy for refractory pulmonary hypertension in neonates: Case series. Pediatr Crit Care Med 2014;15(2):148-54.

More K, Sakhuja P, Shah PS. Minimally invasive surfactant administration: A meta-narrative review. JAMA Pediatr. 2014 Oct;168(10):901-8.

Mullowney T, Manson D, Kim R, Stephens D, Shah V, Dell S. Primary ciliary dyskinesia and neonatal respiratory distress. Pediatrics 2014;134(6):1160-6.

Noori S, McNamara P, Jain A, Lavoie P, Wickremasinghe A, Merritt TA, Solomon T, Sekar K, Attridge J, Swanson J, Gillam-Krakauer M, Reese J, Poindexter B, Brook M, Auchus R, Clyman R and PDA Ligation/Hypotension


Trial Investigators. Catecholamine-resistant Hypotension and Myocardial Performance Following Patent Ductus Arteriosus Ligation. J Perinatol. 2015 Feb;35(2):123-7.

Ohlsson A, Shah VS, Stade BC. Vaginal chlorhexidine during labour to prevent early-onset neonatal group B streptococcal infection. Cochrane Database Syst Rev 2014;12:CD003520.

Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database Syst Rev 2014;(6):CD007467.

Panzuk J, Unger S, O’Connor D, Lee SK. Human donor milk for the vulnerable infant; a Canadian perspective. Int Breastfeed J. 2014 Apr 17;9:4.

Poets CF, Roberts RS, Schmidt B, Whyte RK, Asztalos EV, Bader D, Bairam A, Moddemann D, Peliowski A, Rabi Y, Solimano A, Nelson H, Canadian Oxygen Trial Investigators: Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study at 5 years of age (MACS-5). Journal of Pediatrics. 2014;165(4):666-71.

Shah PS, Hakak H, Mohamed A, Shah J, Young J, Kelly E. Oxygen saturation profile in healthy term and late preterm neonates: A prospective cohort study. J Perinatol. 2014 Dec;34(12):917-20.

Shah PS, Lee SK, Lui K, Sjors G, Mori R, Reichman B, Håkansson S, San Feliciano L, Modi N, Adams M, Darlow B, Fujimura M, Kusuda S, Haslam R, Mirea L. The International Network for Evaluating Outcomes of very low birth weight, very preterm neonates (iNeo): A protocol for collaborative comparisons of international health services for quality improvement in neonatal care. BMC Pediatr. 2014 Apr 23;14:110.

Shah PS, Shah N. Heparin-bonded catheters for prolonging the patency of central venous catheters in children. Cochrane Database Syst Rev. 2014 Feb 25;(2):CD005983.

Soraisham AS, Singhal N, Aziz K, Lodha A, Lee SK, Shah PS and the Canadian Neonatal Network. Neonatal Outcomes Following Extensive Cardiopulmonary Resuscitation in Delivery Room for Preterm Infants’ < 33 Weeks: A Population Based Cohort Study. Resuscitation. 2014 Feb;85(2): 238-43.

Stevens BJ, Yamada J, Estabrooks CA, Stinson J, Campbell F, Scott SD, Cummings G; CIHR Team in Children’s Pain. Pain in hospitalized children: Effect of a multidimensional knowledge translation strategy on pain process and clinical outcomes. Pain 2014 Jan;155(1):60-8.

Stevens BJ, Yamada J, Promislow S, Stinson J, Harrison D, Victor JC, On Behalf of Members of the CIHR Team in Children’s Pain. Implementation of multidimensional knowledge translation strategies to improve procedural pain in hospitalized children. Implement Sci. 2014 Nov 25;9:120.

Taddio A, Ho T, Vyas C, Thivakaran S, Jamal A, Ilersich AF, Hogan ME, Shah V. A randomized controlled trial of clinician-led tactile stimulation to reduce pain during vaccination in infants. Clinical Pediatrics 2014;53(7):639-44.

Taddio A, Ipp M, Vyas C, Parikh C, Smart S, Thivakaran S, Jamal A, Stephens D, Shah V. Teaching parents to manage pain during infant immunizations: Laying the foundation for better pain management practices. Clin J Pain 2014,11:987-94.

Taddio A, MacDoland NE, Smart S, Parikh C, Allen V, Halperin B, Shah V. Impact of a parent directed pamphlet about pain management during infant vaccinations on maternal knowledge and behavior. Neonatal Netw 2014;33:74-82.

Taddio A, Smart S, Sheedy M, Yoon EW, Vyas C, Parikh C, Pillai Riddell R, Shah V. Impact of prenatal education on maternal utilization of analgesic interventions at future infant vaccinations: A cluster randomized trial. Pain 2014;155:1288-92.

Thatrimontrichai A, Chanvitan P, Janjindamai W, Dissaneevate S, Jefferies A, Shah V. Trends in neonatal sepsis in a neonatal intensive care unit in Thailand before and after construction of a new facility. Asian Biomedicine 2014;8(6):771-8.

Unger S, Gibbins S, Zupancic J, O’Connor D. Study protocol, DoMINO: Donor milk for improved neurodevelopmental outcomes. BMC Pediatr 2014;14:123.

Valentino PL, Church PC, Shah PS, Beyene J, Griffiths AM, Feldman BM, Kamath BM. Hepatotoxicity due to Methotrexate Therapy in Children with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis. Inflamm Bowel Dis. 2014 Jan;20(1):47-59.

Van Mieghem T, Al-Ibrahim A, Deprest J, Lewi L, Langer JC, Baud D, O’Brien K, Beecroft R, Chaturvedi R, Jaeggi E, Fish J, Ryan G. Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature. Ultrasound Obstet Gynecol. 2014 Jun;43(6):611-9.

Van Mieghem T, De Heus R, Lewi L, Klaritsch P, Kollmann M, Baud D, Vial Y, Shah PS, Ranzini AC, Mason L, Raio L, Lachat R, Barrett J, Khorsand V, Windrim R, Ryan G. Prenatal management of monoamniotic twin pregnancies. Obstet Gynecol. 2014 Sep;124(3):498-506.

Warre R, O’Brien K, Lee SK. Parents as the primary caregiver for their infant in the NICU: Benefits and challenges. NeoReviews 2014;15(11):pp. e472 -e477.

Weisz D, Jain A, Ting J, McNamara P, EL-Khuffash A. Neonatology. Non-Invasive Cardiac Output

8110-Year Report

Monitoring in Preterm Infants Undergoing Patent Ductus Arteriosus Ligation: A Comparison with Echocardiography. 2014 Oct 1;106(4):330-336.

Weisz D, More K, McNamara P, Shah PS. PDA ligation and risk of mortality and morbidities: A systematic review and meta-analysis. Pediatrics. 2014 Apr;133(4):e1024-46.

Windrim R, Ryan G, LeBouthillier F, Campisi P, Kelly E, Baud D, Yoo S-J, Deprest J. Development and use of a high-fidelity simulator for fetal endotracheal balloon occlusion (FETO) insertion and removal. Prenat Diagn 2014;34(2): 180-4.

Wong J, Shah PS, Yoon EW, Yee W, Lee S, Dow K. Inotrope Use among Extremely Preterm Infants in Canadian Neonatal Intensive Care Units: Variation and Outcomes. Am J Perinatol. 2015 Jan;32(1):9-14.

2013Abdullah K, Kendzerska T, Shah PS, Uleryk E, Parkin PC. Efficacy of oral iron therapy in improving the

developmental outcome of pre-school children with non-anemic iron deficiency (NAID): A systematic review. Public Health Nutr. 2013;16(8):1497-506.

Alali A, McCredie V, Golan E, Shah PS, Nathens A. Beta blockers for acute traumatic brain injury:

A systematic review and meta-analysis. [Epub ahead of print Sep 6 2013] Neurocrit Care. doi:10.1007/s12028-013-9903-5.

Asztalos EV, Murphy KE, Andrew R. Willan AR, Matthews SG, Ohlsson A, Saigal SJ, Armson BA, Kelly EN,

Delisle MF, Gafni A, Lee SK, Sananes, R, Rovet J, Guselle P, Amankwah K, Saleem M, Sanchez J, for the MACS-5 Collaborative Group. Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study: Outcomes in children at 5 years of age (MACS-5). JAMA Pediatr. 2013;167(12):1102-10.

Avila ML, Shah V, Brandao LR. Systematic review on heparin-induced thrombocytopenia in children: a call to action. J Thromb Haemost. 2013;11(4):660-9.

Barbier A, Boivin A, Yoon W, Vallerand D, Platt RW, Audibert F, Barrington K, Shah PS, Nuyt AM, and the Canadian Neonatal Network. New Canadian reference curves for head circumference at birth, by gestational age. Pediatrics. 2013;131(4):e1158-67.

Bassil KL, Collier S, Mirea L, Yang J, Seshia M, Shah PS, Lee SK and the Canadian Neonatal Network. Association between congenital anomalies and area-level deprivation among infants in neonatal intensive care units. Am J Perinatol. 2013;30(3):225-32.

Bassil KL, Shah PS, Shah V, Ye XY, Lee SK, Jefferies AL; and the Canadian Neonatal Network. Impact of late preterm and early term infants on Canadian neonatal intensive care units.[Epub ahead of print May 31, 2013] Am J Perinatol. doi:10.1055/s-0033-1347364.

Baud D, Lausman A, Alfaraj MA, Seaward G, Kingdom J, Windrim R, Langer JC, Kelly EN, Ryan G: Expectant management compared with elective delivery at 37 weeks for gastroschisis. Obstet Gynecol. 2013;121(5):990-8.

Baud D, Windrim R , Kachura JR, Jefferies A, Pantazi S , Shah PS, Langer JC, Forsey J, Chaturvedi RR,

Jaeggi E, Keating S, Chiu P, Ryan G. Minimally invasive fetal therapy for hydropic lung masses: 3 different approaches and review of the literature. Ultrasound Obstet Gynecol. 2013;42(4):440-8.

Baud D, Windrim R, Keunen J, Kelly EN, Shah P, van Mieghem T, Seaward PG, Ryan G: Fetoscopic laser therapy for twin-twin transfusion syndrome before 17 and after 26 weeks’ gestation. Am J Obstet Gynecol. 2013;208(3):197.e1-7.

Behpour A,Shah PS, Mikulis D, Kassner A. Cerebral blood flow abnormalities in children with sickle cell disease: A systematic review. Pediatr Neurol. 2013;48(3):188-99.

Bracht M, O’Leary L, Lee SK, O’Brien K. Implementing family-integrated care in the NICU: a parent education and support program. Adv Neonatal Care. 2013;13(2):115-26.

Brignardello-Peterson R, Carrasco-Labra A, Shah PS, Azarpazhooh A. A practitioner’s guide to developing critical appraisal skills. What is the difference between clinical and statistical significance? J Am Dent Assoc. 2013;144(7):780-6. Canadian Pediatric Society, Critch J. Oral rehydration therapy. Pediatr Child Health. 2013. In press.

Chang HH, Larson J, Blencowe H, Spong CY, Howson CP, Cairns-Smith S, Lackritz EM, Lee SK, Mason E, Serazin AC, Walani S, Simpson JL, Lawn JE, Born Too Soon preterm prevention analysis group. Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index. Lancet. 2013;381(9862):223-34.

Clyman R, Wickremasinghe A, Merritt A, Solomon T, McNamara P, Jain A, Singh J, Chu A, Noori S, Sekar K, Lavoie P, Attridge J, Swanson J, Gillam-Krakauer M, Reese J, DeMauro S, Poindexter B, Aucott S, Satpute M, Fernandez E, Auchus E, and PDA Ligation/Hypotension Trial Investigators. Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones. J Pediatr. In press.

Coles N, Wolfe-Wylie M, O’Brien K, Unger S. Sepsis and shock in a term neonate. Ped Child Health. 2013;18(9):497-9.

de Kluiver E, Offringa M, Walther FJ, Duvekot JJ, de Laat MW. [Perinatalpolicy in cases of extreme prematurity; an investigation into the implementation of the guidelines]. Ned TijdschrGeneeskd. 2013;157(0):A6362.


Duong HH, Mirea L, Shah PS, Yang J, Lee SK, Sankaran K and the Canadian Neonatal Network. Retrospective analyses of pneumothorax in neonates: Trends predictors and outcomes. J Neonatal-Perinatal Med. In press.

El-Khuffash A, Herbozo C, Jain A, Lapointe A, McNamara PJ. Targeted neonatal echocardiography (TnECHO) service in a Canadian neonatal intensive care unit: A 4-year experience. J Perinatol. 013;33(9):687–90.

El-Khuffash A, Jain A, McNamara P. Ligation of a patent ductus arteriosus in preterm infants: Understanding the physiology. J Pediatr. 2013;162(6):1100-6.

Enomoto M, Amish Jain, Pan J, Shifrin Y, Van Vliet T, McNamara PJ, Jankov RP, Belik J. Newborn rat response to single versus combined cGMP-dependant pulmonary vasodilators. Am J Physiol Lung Cell Mol Physiol. 2014;306(2):L207-15.

Esquinas A, Arie S, BaHammam A, Scala R, Seikmeirer R, Koksal GM, Celikel T, Shah PS, Mazela J, Mukhopadhyay A, Nasilowski J. Aerosol therapy during non-invasive mechanical ventilation: A systematic review of clinical implications. Can J Resp Therapy. 2013. In press.

Galarza-Winton ME, Dicky T, O’Leary L, Lee SK, O’Brien K. Implementing family-integrated care in the NICU: educating nurses. Adv Neonatal Care. 2013;13(5):335-40.

Ge W, Mirea L, Yang J, Bassil K, Lee S, Shah PS and the Canadian Neonatal Network. Prediction of neonatal outcomes in extremely preterm neonates in Canadian NICUs. Pediatrics. 2013;132(4):e876-e885.

Gibbins S, Wong S, Unger S, O’Connor D. Donor human milk for preterm infants: Practice considerations. J Neonatal Nurs. 2013;19(4):175-181.

Harel Z, Harel S, Wald R, Shah PS, Bell C. Gastrointestinal adverse events with kayexalate use: A

systematic review. Am J Med. 2013;126(3):264.e9-24.

Harel Z, Sholzberg M, Pavenski K, Harel S, Wald R, Bell CR, Shah PS, Perl J. Novel oral anticoagulants and bleeding risk among patients with chronic kidney disease: A systematic review and meta-analyses. J Am Soc Nephrol. 2013. In press.

Hellmann J, Williams C, Ives-Baines L, Shah PS. Withdrawal of artificial nutrition and hydration in the NICU: Parental perspectives. Arch Dis Child Fetal & Neonatal Ed. 2013;98(1):F21-5.

Jain A, Deshpande P, Shah PS. Peripherally inserted central catheter associated complication rates in relation to catheter tip position in neonates. J Perinatol. 2013;33(4):307-12.

Jain A, McNamara P. Persistent pulmonary hypertension of the newborn: Physiology, hemodynamic assessment and novel therapies. Current Pediatric Reviews. 2013;9:55-66.

Janvier A, Shah PS. The premature lottery in Canadian grey zones. Current Pediatric Reviews. 2013;9:25-31

Jefferies A, Lyons E, Shah PS, Shah V. Impact of late preterm birth on neonatal intensive care resources in a tertiary perinatal centre. Am J Perinatol. 2013;30(7):573-8.

Khuffash A, McNamara P, Lapointe A, Jain A. Adrenal function in preterm infants undergoing patent ductus arteriosus ligation. Neonatology. 2013;104(1):28-33.

Leslie AT, Jain A, El-Khuffash A, Keyzers M, Rogerson S, McNamara PJ. Evaluation of cerebral electric activity and cardiac output after patent ductus arteriosus ligation in preterm infants. J Perinatol. 2013;33(11):861-6.

Macdonell K, Christie K, Robson K, Pytlik K, Lee SK, O’Brien K. Implementing family-integrated care in the NICU: Engaging veteran parents in program design and delivery. Adv Neonatal Care. 2013;13(4):262-9.

McNamara P, Jain A. Patent ductus arteriosus treatment in preterm infants – time to consider shunt volume? J Perinatol. 2013;33(3):248-9.

Mestre TA, Shah PS, Marras C, Lang A. The other face of placebo: the lessebo effect in Parkinson’s disease. Meta-analyses. Neurology. 2013. In press.

Mirea L, Yang J, Paterson AD, Shah V, Bassil K, Lee SK, Shah PS. Relationship of mode of conception and sex concordance with mortality/morbidity in preterm twins. Twin Res Hum Genet. 2013;16(5):985-93.

Mohamed A, Nasef N, Shah V, McNamara P. Vasopressin as a rescue therapy for refractory pulmonary hypertension in neonates: Case series. [Epub ahead of print Oct 17, 2013] Pediatr Crit Care Med. 2014;15(2):148–54.

Mohamed T, Shah PS, Lee K-S. Magnesium for neonatal hypoxic ischemic encephalopathy. A systematic review and meta-analysis. J Perinatology. 2013;33(9):663-9.

Moore A, Farell K, Leibel S, Vachharajani A. Optimizing temperature during resuscitation. NeoReviews. 2013;14(6):e329-e31.

Morais M, Mehta C, Murphy K, Shah PS, Giglia L, Smith PA, Bassil K, McDonald SD. How often are late preterm births due to non-evidence based practices? Analysis from two tertiary referral centers in a nationalized health care system – a retrospective cohort study. BJOG. 2013;120(12):1508-14.

Mukerji A, Narciso J, Moore C, McGeer A, Kelly E, Shah V. An observational study of the hand hygiene initiative: A comparison of pre- and post-intervention outcomes. BMJ Open. 2013;3(5).

Nir M, Ray JG, Shah PS, Berger H, Kingdom J. Should we use customized fetal growth percentiles in urban Canada? Journal of Obstetrics and Gynecology Canada. In press.

8310-Year Report

O’Brien K, Bracht M, Macdonell K, McBride T, Robson K, O’Leary L, Christie K, Galarza M, Dicky T, Levin A, Lee SK. A pilot cohort analytic study of Family Integrated Care in a Canadian neonatal intensive care unit. BMC Pregnancy Childbirth. 2013;13(Suppl 1):S12.

O’Connor DL, Unger S. Post-discharge nutrition of the breastfed preterm infant. [Epub ahead of print May 21, 2013] Semin Fetal Neonatal Med. doi: 10.1016/j.siny.2013.05.001.

Offringa M, Needham AC, Chan WW; StaR Child Health group. StaR Child Health:improving global standards for child health research. Early Hum Dev. 2013;89(11):861-4.

Offringa M, Newton R. Prophylactic drug management for febrile seizures in children (Review). Evid Based Child Health. 2013;8(4):1376-485.

Onland W, Debray TP, Laughon MM, Miedema M, Cools F, Askie LM, Asselin JM, Calvert SA, Courtney SE, Dani C, Durand DJ, Marlow N, Peacock JL, Pillow J, Soll RF, Thome UH, Truffert P, Schreiber MD, Van Reempts P, Vendettuoli V, Vento G,van Kaam AH, Moons KG, Offringa M. Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study. BMC Pediatr. 2013;13(1):207.

Osborn AJ, Baud D, Macarthur AJ, Propst EJ, Forte V, Blaser S, Windrim R, Seaward G, Keunen J, Shah PS, Ryan G, Campisi P. Multidisciplinary perinatal management of the compromised airway on placental support: lessons learned. [Epub ahead of print July 18, 2013] Prenat Diagn. doi: 10.1002/pd.4200.

Paes B, Mitchell I, Li A, Harimoto T, Lanctôt KL; and The CARESS Investigators. Respiratory-related hospitalizations following prophylaxis in the Canadian registry for palivizumab (2005-2012) compared to other international registries. [Epub ahead of print June 19, 2013] Clin Dev Immunol. doi: 10/1155/2013/917068

Pattani R, Hwang S, Palda V Shah PS. Probiotics for the prevention of antibiotic associated diarrhea and clostridium difficile infection among hospitalized patients: A systematic review and meta-analysis. Open Med. 2013;7(2):e56-67.

Plotogea A, Chiarelli AM, Mirea L, Prummel MV, Chong N, Shumak RS, O’Malley FP, Holloway CM; Breast Screening Styd Group. Factors associated with wait times across the breast cancer treatment pathway in Ontario. [Epub August 19, 2013] SpringerPlus. doi: 10.1186/2193-1801-2-388.

Schmidt B, Whyte RK, Asztalos EV, Moddemann D, Poets C, Rabi Y, Solimano A, Roberts RS; for the Canadian Oxygen Trial (COT) Group: Effects of targeting higher vs. lower arterial oxygen saturations on death or disability in extremely preterm infants: A randomized clinical trial. JAMA. 2013;309(20):2111-20.

Schoenmaker NJ, Haverman L, Tromp WF, van der Lee JH, Offringa M, Adams B,Bouts AH, Collard L, Cransberg K, van Dyck M, Godefroid N, van Hoeck K,Koster-Kamphuis L, Lilien MR, Raes A, Taylan C, Grootenhuis MA, Groothoff JW. Children of non-Western origin with end-stage renal disease in the Netherlands, Belgium and a part of Germany have impaired health-related quality of life compared with Western children. [Epub ahead of print Nov 13, 2013] Nephrol Dial Transplant. doi: 10.1093/ndt/gft436.

Schoenmaker NJ, Tromp WF, van der Lee JH, Offringa M, Craig JC, Groothoff JW. Quality and consistency of clinical practice guidelines for the management of children on chronic dialysis. Nephrol Dial Transplant. 2013;28(12):3052-61.

Shah PS , Yoon W , Kalapesi Z , Bassil K , Dunn M , Lee SK. Seasonal variations in healthcare-associated infection in neonates in Canada. Arch Dis Child Fetal Neonatal Ed. 2013;98(1):F65-9.

Shah V, Warre R, Lee S. Quality Improvement Initiatives in Neonatal Intensive Care Unit Networks: Achievements and Challenges. Acad Pediatr. 2013;13(6 Suppl):S75-83.

Soraisham AS, Singhal N, Aziz K, Lodha A, Lee SK, Shah PS; and the Canadian Neonatal Network. Neonatal outcomes following extensive cardiopulmonary resuscitation in delivery room for preterm infants’ <33 weeks: A population-based cohort study. Resuscitation. In press.

Stritzke A, Smyth J, Synnes A, Lee SK, Shah PS and the Canadian Neonatal Network. Transfusion associated necrotizing enterocolitis (TANEC) in Preterm Neonates. Arch Dis Child Fetal Neonatal Ed. 2013;98(1):F10-4.

Taddio A, Ho T, Vyas C, Thivakaran S, Jamal A, Ilersich AF, Hogan M-E, Shah V. A randomized controlled trial of clinician-led tactile stimulation to reduce pain during vaccination in infants. Clin Pediatr. In press.

Taddio A, Shah V, Leung E, Wang J, Parikh C, Smart S, Hetherington R, Ipp M, Riddell RP, Sgro M, Jovicic A, Franck L. Knowledge translation of the HELPinKIDS clinical practice guideline for managing childhood vaccination pain: Usability and knowledge uptake of educational materials directed to new parents. [Epub ahead of print Feb 8, 2013] BMC Pediatr. doi: 10.1186/1471-2431-13-23.

Tan D, Murphy K, Shah PS, Walmsley S. Herpes simplex virus type 2 and HIV progression: a systematic review of observational studies. [Epub ahead of print Oct 28, 2013] BMC Infect Dis. doi: 10.1186/1471-2334-13-502.

van Laerhoven H, de Haan TR, Offringa M, Post B, van der Lee JH. Prognostic tests in term neonates with hypoxic-ischemic encephalopathy: a systematic review. Pediatrics. 2013;131(1):88-98.


Walker MJ, Chiarelli AM, Knight JA, Mirea L, Glendon G, Ritvo P. Perceived risk and adherence to breast cancer screening guidelines among women with a familial history of breast cancer: A review of the literature. Breast. 2013;22(4):395–404.

Walker MJ, Chiarelli AM, Mirea L, Glendon G, Ritvo P, Andrulis IL, Knight JA. Accuracy of self-reported screening mammography use: Examining recall among female relatives from the Ontario site of the Breast Cancer Family Registry. [Epub August 1, 2013] ISRN Oncology. doi: 10.1155/2013/810573.

Weisz D, More K, McNamara P, Shah PS. PDA ligation and risk of mortality and morbidities: A systematic review and meta-analysis. Pediatrics. In press.

Windrim R, Ryan G, LeBouthillier F, Campisi P, Kelly E, Baud D, Yoo SJ, Deprest J: Development and use of a high-fidelity simulator for fetal endotracheal balloon occlusion (FETO) insertion and removal. [Epub ahead of print Nov 27, 2013] Prenatal Diagn. doi: 10.1002/pd.4284.

Wong C, Mak M, Shivananda S, Yang J, Shah PS, Seidlitz W, Pemberton J, Fitzgerald PG, Cameron BH and the Canadian Neonatal Network. Outcomes of neonatal patient ductus arteriosus ligation in Canadian neonatal units without pediatric surgery programs. J Pediatr Surg. 2013;48(5):909-14.

Zhang Q, Macartney J, Sampaio L, O’Brien K. High frequency jet ventilation during initial management, stabilization, and transport of newborn infants with congenital diaphragmatic hernia: A case series. [E-pub ahead of print Jan 2, 2013] Crit Care Res Pract. doi: 10.1155/2013/937871.

2012Anderson LN, Cotterchio M, Mirea L, Ozcelik H, Kreiger N. Passive cigarette smoke exposure during various periods of life, genetic

variants, and breast cancer risk among never smokers. Am J Epidemiol. 2012;175(4):289–301.

Avila ML, Shah PS, Brandeo LR. Different unfractionated heparin doses for preventing arterial thrombosis in children undergoing cardiac catheterization. (Protocol). Cochrane Database Syst Rev. 2012;11:CD010196.

Azarpazhooh A, Shah PS. Nonsurgical root canal treatment may reduce the prevalence and severity of pain of endodontic origin within 1 day following treatment and substantially to minimal levels in 7 days. J Evid Based Dent Pract. 2012;12(1):12-3.

Baird R, Puligandla P, Skarsgard E, Laberge JM , CAPSNet. Infectious complications in the management of gastroschisis. Pediatr Surg Int. 2012;28(4):399-404.

Bassil K, Shah PS, Barrington KJ, da Silva O, Harrison A, Lee SK and the Canadian Neonatal Network. Changing epidemiology and outcomes of preterm twins and triplets in Canada – 2003-2008. Am J Perinatol. 2012;29(4):237-44.

Bassil KL, Collier S, Mirea L, Yang J, Seshia MM, Shah PS, Lee SK. Association between congenital anomalies and area-level deprivation among infants in neonatal intensive care units. Am J Perinatol. 2013;30(3):225–32.

Boyajian T, Shah PS, Murphy KE. HIV positive pregnant women receiving HAART: a matched cohort study of pregnancy outcomes. J Obstet Gynaecol Can. 2012;34(2):136–141.

Braga JR, Santos I, McDonald M, Shah PS, Ross H. Factors associated with the development of cardiac allograft vasculopathy: A systematic review of observational studies. Clin Transplant. 2012;26:E111-24.

Brignardello-Petersen R, Carrasco-Labra A, Araya I, Yanine N, Beyene J, Shah PS. Adjuvant laser therapy for the prevention of complications

after surgical removal of impacted mandibular third molars: A systematic review and meta-analysis. J Oral Maxillofac Surg. 2012;70(8):1789-801.

Brindle ME, Flageole H, Wales PW, CAPSNet. Influence of maternal factors on health outcomes in gastroschisis: a Canadian population-based study. Neonatology. 2012;102(1):45-52.

Caldwell PH, Dans L, de Vries MC, Newman Ba Hons J, Sammons H, Spriggs M, Tambe P, Van’t Hoff W, Woolfall K, Young B, Offringa M; StaR Child Health Group. Standard 1: consent and recruitment. Pediatrics. 2012;129(Suppl 3):S118-23.

Chahal J, Marks PH, MacDonald PB, Shah PS, Theodoropoulos J, Ravi B,Whelan DB. Anatomic Bankart repair compared with non-operative treatment and/or arthroscopic lavage for first-time traumatic shoulder dislocation: a systematic review and meta-analysis. Arthroscopy. 2012;28:565-75.

Chiarelli AM, Edwards SA, Sheppard AJ, Mirea L, Chong N, Paszat L, Shumak RS, O’Malley FP. Favourable prognostic factors of subsequent screen-detected breast cancers among women aged 50-69. Eur J Cancer Prev. 2012;21(6):499–506.

Chierichetti M, Engelberts D, EL-Khuffash A, Babyn P, Post M, Kavanagh BP. Continuous negative abdominal distension recruits atelectatic lungs. Crit Care Med. 2012;40(6):1864-72.

Chirinian N, Isayama T, UjiAtsuko A, Shah V. Neonatal Care in Japanese NICU: Notes based on a site visit. Neonatal Netw. 2012;31(2):89-96.

Chirinian N, Shah V. Does decreasing the frequency of changing intravenous administration sets (>24 h) increase the incidence of sepsis in neonates receiving total parenteral nutrition? Pediatr Child Health. 2012;17(9):501-4.

Chung B, Hinek A, Keating S, Weksberg R, Shah V, Blaser S, Hawkins C, Chitayat D.

8510-Year Report

Overgrowth with increased proliferation of fibroblast and matrix metalloproteinase activity related to reduced TIMP1: A newly recognized syndrome? Am J Med Genet A. 2012;158A(10):2371-81.

Coleman BL, McGeer A, Halperin SA, Langley JM, Shamout Y, Taddio A, Shah V, NcNeil SA. A randomized control trial comparing immunogenicity, safety and preference for self- versus nurse-administered intradermal influenza vaccine. Vaccine. 2012;30(44):6287-93.

Cowan KN, Puligandla PS, Laberge JM, Skarsgard ED, Bouchard S, Yanchar N, Kim P, Lee S, McMillan D, von Dadelszen P. The gastroschisis prognostic score: reliable outcome prediction in gastroschisis. J Pediatr Surg. 2012;47(6):1111-7.

de Haan TR, Bijleveld YA, van der Lee JH, Groenendaal F, van den Broek MP,Rademaker CM, van Straaten HL, van Weissenbruch MM, Vermeulen JR, Dijk PH, DudinkJ, Rijken M, van Heijst A, Dijkman KP, Gavilanes D, van Kaam AH, Offringa M, Mathôt RA. Pharmacokinetics and pharmacodynamics of medication in asphyxiatednewborns during controlled hypothermia. The PharmaCool multicenter study. BMC Pediatr. 2012;12:45.

Dunn M, Jefferies A, Fetus and Newborn Committee, Canadian Paediatric Society. Recommendations for neonatal surfactant therapy – addendum. Paediatr Child Health. 2012;17(3):137–40.

Eliason SH, Whyte H , Dow K , Cronin CM , Lee S , CNN. Variations in transport outcomes of outborn infants among Canadian neonatal intensive care units. Am J Perinatol. 2013;30(5):377-82.

El-Khuffash A, Jain A, Dragulescu A, McNamara PJ, Mertens L. Acute changes in myocardial systolic function in preterm infants undergoing patent ductus arteriosus ligation. A tissue doppler and myocardial deformation study. J Am Soc Echocardiogr. 2012;25(10):1058-67.

El-Khuffash A, Mertens L. Early treatment of a patent ductus arteriosus. Do we know what we are doing? Pediatr Crit Care Med. 2012;13(3):363-4.

El-Khuffash A, Unger S. The Concept of Milk Kinship in Islam: Issues Raised when Offering Preterm Infants of Muslim Families Donor Human Milk. J Hum Lact. 2012;28(2):125-7.

Ellenberg S, Fernandes RM, Saloojee H, Bassler D, Askie L, Vandermeer B,Offringa M, Van der Tweel I, Altman DG, van der Lee JH; StaR Child Health Group. Standard 3: data monitoring committees. Pediatrics. 2012;129(Suppl 3):S132-7.

Finan E, Bismilla Z, Campbell C, LeBlanc V, Jefferies A, Whyte H. Improved procedural performance following a simulation training session may not be transferable to the clinical environment. J Perinatol. 2012;32(7):539-44.

Finan E, Bismilla Z, Whyte HE, Leblanc V, McNamara PJ . High-fidelity simulator technology may not be superior to traditional low-fidelity equipment for neonatal resuscitation training. J Perinatol. 2012;32(4):287-92.

Gilbert NL, Fell DB, Joseph KS, Liu S, León JA, Sauve R, for the Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. Temporal trends in sudden infant death syndrome in Canada from 1991 to 2005: contribution of changes in cause of death assignment practices and in maternal and infant characteristics. Paediatr Perinat Epidemiol. 2012;26(2):124-30.

Gupta V , Whelan KF , Schneider L , Farrokhyar F , Shivananda S , Lee S , Sabri K. National variations in retinopathy of prematurity screening criteria in Canada: existent guidelines and actual practice patterns. Canadian journal of ophthalmology. Can J Ophthalmol. 2012;47(6):473-8.

Harel Z, Gilbert C, Wald R, Bell C, Juurlink D, Perl J, Beyene J, Shah PS. The effect of combination therapy with aliskiren and blockers of the renin angiotensin system on hyperkalemia and acute kidney injury: A systematic review and meta-analyses. BMJ. 2012;344:e42.

Hartling L, Wittmeier KD, Caldwell PH, van der Lee JH, Klassen TP, Craig JC, Offringa M; StaR Child Health group. StaR Child Health: developing evidence-basedguidance for the design, conduct, and reporting of pediatric trials. Clin Pharmacol Ther. 2011;90(5):727-31.

Hartling L, Wittmeier KD, Caldwell P, van der Lee H, Klassen TP, Craig JC,Offringa M; StaR Child Health Group. StaR child health: developing evidence-basedguidance for the design, conduct, and reporting of pediatric trials. Pediatrics. 2012;129(Suppl 3):S112-7.

Hui D, Okun N, Murphy K, Kingdom J, Uleryk E, Shah PS. Combinations of maternal serum markers to predict adverse pregnancy Outcome: A systematic review. J Obstet Gynaecol Can. 2012;34(2):142–153.

Isayama T, Lee SK, Mori R, Kusuda S, Fujimura M, Xiang Ye, Shah PS and the Canadian Neonatal Network. Comparison of mortality and morbidity of very low birth weight infants between Canada and Japan. Pediatrics. 2012;130(4):e957-65.

Jain A, McNamara P, Ng E, El-Khuffash A. The use of targeted neonatal echocardiography to confirm placement of peripherally inserted central catheters in neonates. Am J Perinatol. 2012;29(2):101-106.

Jain A, Sehgal M, EL-Khuffash A, Khadawardi E, McNamara PJ. use of targeted neonatal echocardiography to prevent postoperative cardiorespiratory instability after PDA ligation. J Pediatr. 2012;160(4):584-589.


Jansen LA , Safavi A , Lin Y , MacNab YC , Skarsgard ED, CPSN. Preclosure fluid resuscitation influences outcome in gastroschisis. Am J Perinatol. 2012;29(4):307-12.

Jefferies A, Fetus and Newborn Committee, Canadian Paediatric Society. Kangaroo care for the preterm infant and family. Paediatr Child Health. 2012;17(3):141-6.

Jefferies A, Fetus and Newborn Committee, Canadian Paediatric Society. Postnatal corticosteroids to treat or prevent chronic lung disease in preterm infants. Paediatr Child Health. 2012;17(10):573–4.

Jefferies A, Kirpalani H, Fetus and Newborn Committee, Canadian Paediatric Society. Management and counselling for anticipated extremely preterm birth. Paediatr Child Health. 2012;17(8):443-4.

Joseph KS, Liu S, Rouleau J, Lisonkova S, Hutcheon J, Sauve R, Allen AC, Kramer MS for the Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System. Influence of definition-based versus pragmatic birth registration on international comparisons of perinatal and infant mortality: a population-based retrospective study. BMJ. 2012;344:e746.

Kanji JN, Laverdiere M, Rotstein C, Walsh T, Shah PS, Haider S. Treatment of invasive candidiasis in neutropenic patients: Systematic review of randomized controlled treatment trials. Leuk Lymphoma. 2013;54(7):1479-87.

Ko G, Shah P, Lee SK, Asztalos E. Impact of maternal education on cognitive and language scores at 18 to 24 months among extremely preterm neonates. Am J Perinatol. 2013;30(9):723-30.

Ko G, Shah PS, Kovacs L, Ojah C, Riley P, Lee SK and the Canadian Neonatal Network. Neighborhood income level and outcomes of extremely preterm neonates: Protection conferred by a universal health care system. Can J Public Health. 2012;103(6):e443-7.

Lee A, Ye X, Shah PS. Permissive concepts in neonatology: relationships to neonatal outcomes of preterm infants <27 weeks GA. HK J Pediatr. 2012;17:97-102.

Lee SK, Aziz K , Dunn M , Clarke M , Kovacs L , Ojah C , Ye XY. Transport risk index of physiologic stability, version II (TRIPS-II): A simple and practical neonatal illness severity score. Am J Perinatol. 2013;30(5):395-400.

Lee SK, Ye XY, Singhal N, De La Rue S, Lodha A, Shah PS. Higher altitude and risk of bronchopulmonary dysplasia among preterm infants. Am J Perinatol. 2013;30(7):601-6.

Mills J, Safavi A, Skarsgard ED, CAPSNet. Chylothorax after congenital diaphragmatic hernia repair: a population-based study. J Pediatr Surg. 2012;47(5):842-6.

Mirea L, Sankaran K, Seshia MMK, Ohlsson A, Allen AC, Aziz K, Lee SK, Shah PS, and the Canadian Neonatal Network. Treatment of patent ductus arteriosus and neonatal mortality/morbidities: adjustment for treatment selection bias. J Pediatr. 2012;161(4):689-94.

Mirea L, Infante-Rivard C, Sun L, Bull SB. Strategies for genetic association analyses combining unrelated case-control individuals and family trios. Am J Epidemiol. 2012;176(1):70–9.

Mohamed A, Shah PS. Transfusion associated necrotizing enterocolitis: A meta-analysis of observational data. Pediatrics. 2012;129(3):529-40.

Murphy KE, Willan AR, Hannah ME, Ohlsson A, Kelly EN, Matthews SG, Saigal S, Asztalos E, Ross S, Delisle MF, Amankwah K, Guselle P, Gafni A, Lee SK, Armson BA. Effect of antenatal corticosteroids on fetal growth and gestational age at birth. Obstet Gynecol. 2012;119(5):917-23.

O’Brien K, Campbell C, Havlin L, Wegner L, Shah V. Infant flow biphasic nasal continuous positive airway pressure (BP-NCPAP) vs. infant flow NCPAP for the facilitation of extubation in infants’ ≤ 1,250

grams: A randomized controlled trial. BMC Paediatr. 2012;12:43.

O’Connor DL, Weishuhn K, Rovet J, Vaughan J, Mirabella G, Jefferies A, Campbell DM, Asztalos E, Feldman M, Whyte H, Westall C on behalf of the Post-discharge Feeding Study Group. Visual development of human milk-fed preterm infants provided with extra energy and nutrients after hospital discharge. J Parenter Enteral Nutr. 2012;36(3):349-53.

Offringa M, Newton R. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2012;4:CD003031.

Ohlsson A, Shah PS. Paracetamol (acetaminophen) for patent ductus arteriosus in preterm and/or low-birth-weight infants (Protocol). Cochrane Database Syst Rev. 2012;9:CD010061.

Okwundu CI, Okoromah CAN, Shah PS. Prophylactic phototherapy for preventing jaundice in preterm very low birth weight infants. Cochrane Database Syst Rev. 2012;1:CD007966.

Onland W, Offringa M, van Kaam A. Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. Cochrane Database Syst Rev. 2012;4:CD002311.

Paes B, Mitchell I, Li A, Lanctôt KL and The CARESS Investigators. A comparative study of Respiratory Syncytial Virus (RSV) prophylaxis in premature infants with the Canadian Registry (CARESS). Eur J Clin Microbiol Infect Dis. 2012;31(10):2703-11.

Paes B, Mitchell I, Li A, Lanctôt KL. Respiratory hospitalisations and respiratory syncytial virus prophylaxis in special populations. Eur J Pediatr. 2012;171(5):833-41.

Peng G, Ivanovska J, Kantores C, Van Vliet T, Engelberts D, Kavanagh B, Enomoto M, Belik J, Jain A, McNamara P, Jankov R. Sustained therapeutic hypercapnia attenuates pulmonary rho-kinase

8710-Year Report

activity and ameliorates chronic hypoxic pulmonary hypertension in juvenile rats. Am J Physiol Heart Circ Physiol. 2012;302(12):H2599-611.

Porat S, Aamsalem H, Shah PS, Murphy KE. Transabdominal amnioinfusion for preterm premature rupture of membranes: a systematic review and meta-analyses of randomized and observational studies. Am J Obstet Gynecol. 2012;207(5):393.e1-11.

Pound C, Unger S; Canadian Paediatric Society. The Baby Friendly Initiative: Protecting, promoting and supporting breastfeeding. Pediatr Child Health. 2012;17(6):317-27.

Qiu X, Lodha A, Shah PS, Sankaran K, Seshia M, Jefferies A, Yee W, Lee SK and the Canadian Neonatal Network. Neonatal outcomes of small for gestational age preterm infants in Canada. Am J Perinatol. 2012;29(2):87-94.

Ravi B, Shah PS, Escott B, Jenkinson R, Chahal J, Bogoch E, Kreder H, Hawker G. A Systematic review comparing complications following total hip and total knee arthroplasty for individuals with osteoarthritis versus rheumatoid arthritis. Arthritis Rheum. 2012;64(12):3839-49.

Ritvo P, Edwards SA, Glendon G, Mirea L, Knight JA, Andrulis IL, Chiarelli AM. Beliefs about optimal age and screening frequency predict breast screening adherence in a prospective study of female relatives from the Ontario site of the Breast Cancer Family Registry. BMC Public Health. 2012;12:518. doi: 10.1186/1471-2458-12-518.

Safavi A, Synnes AR, O’Brien K, Chiang M, Skarsgard ED, Chio PP, Canadian Pediatric Surgery Network. Multi-Institutional Follow up of Congenital Diaphragmatic hernia (CDH) patients reveals severe disability and variations in practice. J Pediatr Surg. 2012;47(5):836-41.

Sakhuja P, Whyte H, Finan E. Accuracy of 7-8-9 rule: Neonatal endotracheal intubation. J Nepal Paediatr Soc. 2012;32(1):93.

Sananes R, Manlhiot C, Kelly E, Hornberger LK, Williams WG, MacGregor D, Buncic R, McCrindle BW: Neurodevelopmental outcomes following open heart surgery before 3 months of age. Ann Thorac Surg. 2012;93:1577-83.

Schrey S, Kelly EN, Langer JC, Davies GA, Windrim R, Seaward PG, Ryan G: Fetal thoraco-amniotic shunting for large macrocystic congenital cystic adenomatoid malformations (CCAM) of the lung. Ultrasound Obstet Gynecol. 2012;39(5):515-20.

Sewing C, Kantores C, Ivanovska J, Lee A, Masood A, Jain A, McNamara P, Tanswell K, Jankov R. Therapeutic hypercapnia prevents bleomycin-induced pulmonary hypertension in neonatal rats by limiting macrophage-derived tumor necrosis factor-α. Am J Physiol Lung Cell Mol Physiol. 2012;303(1):L75-87.

Sgro M, Campbell D, Kandasamy S, Shah V. Incidence of chronic bilirubin encephalopathy in Canada, 2007-2008. Pediatrics. 2012;130(4):e886-90.

Shah PS, Sankaran K, Aziz K, Allen AC, Seshia M, Ohlsson A, Lee SK, CNN. Outcomes of preterm infants <29 weeks gestation over 10-year period in Canada: a cause for concern? J Perinatol. 2012;32(2):132-8.

Shah PS, Herbozo C, Aliwalas L, Shah V. Breastfeeding or breastmilk for procedural pain in newborns. Cochrane Database Syst Rev. 2012;12:CD004950.

Shah PS, Ye XY, Synnes A, Rouvinez-Bouali N, Yee W, Lee SK and the Canadian Neonatal Network. Prediction of survival without morbidity for infants born at <33 weeks gestational age: a user friendly graphical tool. Arch Dis Child Fetal Neonatal Ed. 2012;97:F110-F115.

Shah PS. Meta-analysis of neurodevelopmental outcome after room air vs. 100% oxygen resuscitation: Generating

more questions than answers? Neonatology. 2012;102(2):104-6.

Shah V, Jefferies A. Preterm infants receiving heel lance procedure have slightly lower pain scores and quicker time to return to baseline heart rate when held in kangaroo care by the mother than the father. Evid Based Med. 2012;17(5):153-4.

Shah V, O’Brien K. NIPPV after surfactant treatment for RDS reduces the need for mechanical ventilation at 7 days of age and BPD in preterm infants: Interpret results with caution. J Clin Neonatol. 2012;1(3):115-7.

Short J, Shah V, Bernstein P, Downey K, Carvalho J. A single preoperative dose of gabapentin does not improve postcesarean delivery pain management: a randomized, double-blinded, placebo-controlled dose-finding trial. Anesth Analg. 2012;115(6):1336-42.

Singhal N, Lockyer J, Fidler H, Aziz K, McMillan D, Qiu X, Ma X, Du L, Lee SK. Acute Care of At-Risk Newborns (ACoRN): quantitative and qualitative educational evaluation of the program in a region of China. BMC Med Educ. 2012;12:44.

Sinha IP, Altman DG, Beresford MW, Boers M, Clarke M, Craig J, Alberighi OD,Fernandes RM, Hartling L, Johnston BC, Lux A, Plint A, Tugwell P, Turner M, vander Lee JH, Offringa M, Williamson PR, Smyth RL; StaR Child Health Group.Standard 5: selection, measurement, and reporting of outcomes in clinical trials in children. Pediatrics. 2012;129(Suppl 3):S146-52.

Srinivasjois R, Shah S, Shah PS. Biracial couples and adverse birth outcomes: A systematic review and meta-analyses. Acta Obstet Gynecol Scand. 2012;91(10):1134-46.

Steggerda SJ, de Bruïne FT, Smits-Wintjens VEHJ, Walther FJ, van Wezel-Meijler G. Ultrasound detection of posterior fossa abnormalities in full-term neonates. Early Hum Dev. 2012;88(4):233-9.


Stevens BJ, Harrison D, Rashotte J, Yamada J, Abbott LK, Coburn G, Stinson J, Le May S, CIHR Team in Children’s Pain. Pain assessment and intensity in hospitalized children in Canada. J Pain. 2012;13(9):857-65.

Tromp WF, Schoenmaker NJ, van der Lee JH, Adams B, Bouts AH, Collard L,Cransberg K, Van Damme-Lombaerts R, Godefroid N, van Hoeck K, KosterKamphuis L, Lilien MR, Raes A, Offringa M, Groothoff JW. Important differences in management policies for children with end-stage renal disease in the Netherlands and Belgium--report from the RICH-Q study. Nephrol Dial Transplant. 2012;27(5):1984-92.

van der Tweel I, Askie L, Vandermeer B, Ellenberg S, Fernandes RM, SaloojeeH, Bassler D, Altman DG, Offringa M, van der Lee JH; StaR Child Health Group. Standard 4: determining adequate sample sizes. Pediatrics. 2012;129(Suppl 3):S138-45.

van Manen M, Bratu I, Narvey M, Rosychuk RJ, CAPSNet. Use of paralysis in silo-assisted closure of gastroschisis. J Pediatr. 2012;161(1):125-8.e1.

Weisz D, Jain A, McNamara P, EL-Khuffash A. Non-invasive cardiac output monitoring in neonates using bioreactance: A comparison with echocardiography. Neonatology. 2012:102(1):61-67

Wittmeier KD, Craig J, Klassen TP, Offringa M. The mission of StaR ChildHealth is to improve the quality of the design, conduct, and reporting ofpediatric clinical research by promoting the use of modern research standards. Introduction. Pediatrics. 2012;129(Suppl 3):S111.

Wong J, Dow K, Shah PS, Andrews W, Lee SK, Canadian Neonatal Network. Percutaneously placed central venous catheter related blood stream infections in Canadian NICUs: Impact on outcomes and variations. Am J Perinatol. 2012;29(8):629-34.

Wright A, Unger S, Coleman B, Lam PP, McGeer A. Maternal antibiotic

exposure and risk of antibiotic resistance in early onset neonatal sepsis: A case control study. Pediatr Infect Dis J. 2012;31(11):1206-8.

Yee WH, Soraisham AS, Shah VS, Aziz K, Yoon W, Lee SK; Canadian Neonatal Network. Incidence and timing of presentation of necrotizing enterocolitis in preterm infants. Pediatrics. 2012;129(2):e298-304.

Xu W, Bull SB, Mirea L, Greenwood CM. Model-free linkage analysis of a binary trait. Methods Mol Biol. 2012;850:317–45.

Zhang LR, Chiarelli AM, Glendon G, Mirea L, Knight JA, Andrulis IL, Ritvo P. Worry Is good for breast cancer screening: A study of female relatives from the Ontario site of the Breast Cancer Family Registry. [Epub June 28, 2012] J Cancer Epidemiol. doi: 10.1155/2012/545062.

Zhou Q, Cao Y, Lee SK, Cai XD, Chen C, Hu XJ, Huang CQ. Distribution and antibiotic sensitivity of pathogens in neonates with ventilator associated pneumonia. Chin J Perinal Med. 2012;15(8):462-8.

2011Alfaraj MA, Shah PS, Bohn D, Panatazi S, O’Brien K, Chiu PP, Gaiteiro R, Ryan G. Congenital diaphragmatic hernia: Lung:head ratio and lung volume for prediction of outcome. Am J Obstet Gynecol. 2011;205(1):43.e1-8.

Azarpazhooh A, Lawrence H, Limeback H, Shah PS. Xylitol for preventing acute otitis media in children up to 12 years of age. Cochrane Database Syst Rev. 2011;11:CD007095.

Azarpazhooh A, Shah PS. Endodontic surgery prognostic factors. Evid Based Dent. 2011;12(1):12-3.

Baird R, Eeson G, Safavi A, Puligandla P, Laberge JM, Skarsgard ED. Institutional practice and outcome variation in the management of congenital diaphragmatic hernia and

gastroschisis in Canada: a report from the Canadian Pediatric Surgery Network. J Pediatr Surg. 2011;46(5):801-7.

Barrett R, Heddle N, Kirpalani H, Moore RG, Arnold E, Shah PS, Staines A. ‘Someone else’s blood’: Directed blood donation for neonatal transfusion and parental perceptions of risk. J Risk Res. 2011;14:837-45.

Bassil KL, Cole DC, Moineddin R, Lou W, Craig AM, Schwartz B, Rea E. The relationship between temperature and ambulance response calls for heat-related illness in Toronto, Ontario, 2005. J Epidemiol Community Health. 2011;65(9):829-31.

Campitelli MA, Chiarelli AM, Mirea L, Stewart L, Glendon G, Ritvo P, Andrulis IL, Knight JA. Adherence to breast and ovarian cancer screening recommendations for female relatives from the Ontario site of the Breast Cancer Family Registry. Eur J Cancer Prev. 2011;20(6):492–500.

Canadian Pediatric Society, Critch J. Infantile colic: Is there a role for dietary interventions? Pediatr Child Health. 2011;16(1):47-9.

Cronin CM, Baker GR, Lee SK, Ohlsson A, McMillan DD, Seshia MM. Reflections on knowledge translation in Canadian NICUs using the EPIQ method. Healthcare Q. 2011;14(Spec No 3):8-16.

de Bruïne FT, van den Berg-Huysmans A, Leijser LM, Rijken M, Steggerda SJ, van der Grond J, van Wezel-Meijler G. Clinical implications of MRI findings in the white matter in very preterm infants: A two year follow-up study. Radiology. 2011;261(3):899-906.

El-Khuffash A, Kieran E, Palmer K, Molloy EJ. Neonatal respiratory extracorporeal membrane oxygenation (ECMO) referrals from Ireland. Ir Med J. 2011;104(3):78-81.

El-Khuffash A, McNamara PJ. Neonatologist performed functional echocardiography in the neonatal intensive care unit. Seminars Fetal Neonatal Med. 2011;16(1):50-60.

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El-Khuffash A, McNamara PJ. The patent ductus arteriosus ligation decision. J Pediatr. 2011;158(6):1037-8.

El-Khuffash A, Slevin M, McNamara PJ, Molloy EJ. Troponin T, N-terminal Pro Natriuretic Peptide, and a patent ductus arteriosus scoring system predict neurodevelopmental outcome at 2 years or death before discharge in preterm Infants. Arch Dis Child Fetal Neonatal Ed. 2011;96(2):F133-7.

Ewaschuk J, Unger S, Harvey S, O’Connor D, Field C. Effect of pasteurization on immune components of milk: implications for feeding preterm infants. Appl Physiol Nutr Metab. 2011;36(2):175-82.

Ewaschuk J, Unger S, O’Connor D, Stone D, Harvey S, Clandinin T, Field C. Effect of pasteurization on selected immune components of donated human breastmilk. J Perinatol. 2011;31(9):593-8.

Egyepong J, Jain A, Chow P, Godambe S. Parenteral nutrition—ascites with acute renal failure as a complication from an umbilical venous catheter in an extremely low birth weight infant. BMJ Case Rep. 2011. doi: 10.1136/bcr.02.2011.3813.

Fardo DW, Druen AR, Liu J, Mirea L, Infante-Rivard C, Breheny P. Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome. BMC Proc. 2011;5(Suppl 9):S28.

Finan E, Aylward D, Singhal N, Johnston KL, McNamara P, Connelly R, Laforge R, Aziz K. Update on neonatal resuscitation guidelines: A case based review. Paediatrics and Child Health. 2011;16(5):289-294.

Frisk V, Jakobson L, Unger S, Trachsel D, O’Brien K. Long-term neurodevelopmental outcomes of congenital diaphragmatic hernia survivors not treated with estracorporeal membrane oxygenation. J Pediatr Surg. 2011;46(7):1309-18.

Gouin K, Murphy K, Shah PS, on behalf of the Knowledge Synthesis Group on LBW/preterm birth. Effects of cocaine use during pregnancy on low birth weight and preterm birth: systematic review and meta-analyses. Am J Obstet Gynecol. 2011;204(4):340.e1-12.

Hamidi M, Boucher BA, Cheung AM, Beyene J, Shah PS. Fruit and vegetable intake and bone health in women aged 45 and over: a systematic review. Osteoporos Int. 2011;22(6):1681-93.

Han Z, Mulla S, Beyene J, Liao J, McDonald S, on behalf of the Knowledge Synthesis Group on determinants of preterm/LBW births. Maternal underweight and the risk of preterm birth and low birth weight: a systematic review and meta-analyses. Int J Epidemiol. 2011;40(1):65-101.

Jefferies A, Fetus and Newborn Committee and Psychosocial Paediatrics Committee, Canadian Paediatic Society. Selective serotonin reuptake inhibitors in pregnancy and infant outcomes. Paediatr Child Health. 2011;16(9):562–3.

Jefferies A, Shah V. Clinicians prefer simple educational tools for implementing practice change. Med Teach. 2011;33(11):e602-6.

Jefferies A, Simmons B, Ng E and Skidmore M. Assessment of multiple physician competencies in postgraduate training: utility of the structured oral examination. Adv Health Sci Educ Theory Pract. 2011;16(5):569-77.

Kanungo J, James A, Lodha A, McMillan D, Faucher D, Lee SK, Shah PS and the Canadian Neonatal Network. Advanced maternal age and the outcomes of preterm infants: a social paradox? Obstet Gynecol. 2011;118(4):872-877.

Kingdom J, Walker M, Proctor L, Keating S, Shah PS, McLeod A Johannes K, Windrim R, Dodd J. Unfractionated heparin for second trimester placental insufficiency.

A pilot randomized trial. J Thromb Hemostasis. 2011;9(8):1483-92.

Kuster SP, Shah PS, Coleman BL, Lam PP, Tong A, Wormsbecker A, McGeer A. Incidence of influenza in healthy adults and health care workers: A systematic review. PLoS One. 2011;6(10):e26239.

Ladhani N, Shah PS, Murphy K on behalf of Knowledge Synthesis Group on determinants of preterm/LBW births. Prenatal amphetamine exposure and birth outcomes: A systematic review and meta-analyses. Am J Obstet Gynecol. 2011;205(3):219.e1-7.

Lausch E, Janecke A, Bros M, Trojandt S, Alanay Y, De Laet C, Hubner C, Meinecke P, Nishimura G, Matsuo M, Hirano Y, Tenoutasse S, Kiss A, Rosa R, Unger S, Renella R, Bonafe L, Spranger J, Unger S, Zabel B, Superti-Furga A. Genetic deficiency of tartrate-resistant acid phosphatase associated with skeletal dysplasia, cerebral calcifications and autoimmunity. Nat Genet. 2011;43(2):132-7.

Lee SK, Singhal N, Aziz K, Cronin CM, CNN. The EPIQ evidence reviews - practical tools for an integrated approach to knowledge translation. Paediatr Child Health. 2011;16(10):629-30.

Lisonkova S, Sheps SB, Janssen PA, Lee SK, Dahlgren L, Macnab YC. Birth outcomes among older mothers in rural versus urban areas: a residence-based approach. J Rural Health. 2011;27(2):211-9.

Lisonkova S, Sheps SB, Janssen PA, Lee SK, Dahlgren L. Effect of older maternal age on birth outcomes in twin pregnancies: a population-based study. J Perinatol. 2011;31(2):85-91.

Lodha A, Zhu Q, Lee SK, Shah PS and the Canadian Neonatal Network. Neonatal outcomes of preterm infants in breech presentation according to mode of birth. Postgrad Med J. 2011;87(1025):175-9.


Magee LA, von Dadelszen P, Allen VM, Ansermino JM, Audibert F, Barrett J, Brant R, Bujold E, Crane JM, Demianczuk N, Joseph KS, Lee SK, Piedboeuf B, Smith G, Synnes A, Walker M, Whittle W, Wood S, Lee T, Li J, Payne B, Liston RM, CPN Collaborative Group. The Canadian Perinatal Network: a national network focused on threatened preterm birth at 22 to 28 weeks’ gestation. J Obstet Gynaecol Can. 2011;33(2):111-20.

Mitchell I, Paes B, Li A, Lanctot K and The CARESS Investigators. CARESS: The Canadian Registry of Palivizumab. Pediatr Infect Dis J. 2011;30(8):651-5.

Moore A, Costello J, Wieczorek P, Shah V, Taddio A, Carvalho JC. Gabapentin improves postcesarean delivery pain management: a randomized, placebo-controlled trial. Anesth Analg. 2011;112(1):167-73.

Morag I, Eppelman M, Daneman A, Moore A, Shah PS. Long term outcomes of neonatal portal venous thrombosis. J Paediatr Child Health. 2011;47(6):356-60.

Murphy KE, Hannah ME, Willan AR, Ohlsson A, Kelly EN, Stephen G Matthews SG, Saigal S, Asztalos E, Ross S, Delisle MF, Tomat L, Amankwah K, Guselle P, Gafni A, Lee SK, Armson A, for the MACS Collaborative Group: Maternal side-effects after multiple courses of antenatal corticosteroids - the 3 month follow-up of women in the randomised controlled trial of Multiple courses of Antenatal Corticosteroids for preterm birth Study (MACS). J Obstet Gynaecol Can. 2011;33(9):909-21.

Nasef N, Skidmore M, Shah PS. Enablers and disablers allowing trainees’ abstracts to proceed to full manuscripts: lessons from a large neonatal training program. J Perinatol. 2011;31(6):411–6.

Nasr A, Langer JC, CPSN. Influence of location of delivery on outcome inneonates with congenital diaphragmatic hernia. J Pediatr Surg. 2011;46(5):814-6.

O’Carroll C, El-Khuffash A, Walsh K, Knowles S, Molloy EJ. Targeted neonatal echocardiography (TnECHO) and increased detection of intracardiac thrombi and endocarditis in very low birth weight infants. Internet Journal of Paediatrics and Neonatology. 2011;12(2). doi: 10.5580/1ff4.

Ohlsson A, Shah PS on behalf of the Knowledge Synthesis Group on determinants of preterm/LBW births. Effects of the September 11, 2001 disaster on pregnancy outcomes: A systematic review. Acta Obstet Gynecol Scand. 2011;90(1):6-18.

Onland W, Offringa M, Cools F, De Jaegere AP, Rademaker K, Blom H, CavatortaE, Debeer A, Dijk PH, van Heijst AF, Kramer BW, Kroon AA, Mohns T, van StraatenHL, te Pas AB, Theyskens C, van Weissenbruch MM, van Kaam AH. Systemic hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trial. BMC Pediatr. 2011;9;11:102.

Perlman M, Shah PS. HIE: Outcomes and predictions. J Pediatr. 2011;158(Suppl 2):e51-41.

Rosier FMF, van Wezel-Meijler G, Kaschula ROC, Wranz PAB, Odendaal HJ, de Vries JIP. Placental histology related to fetal brain sonography in fetuses at risk for preterm birth. Arch Dis Child Fetal Neonatal Ed. 2011:96(1):F53-8.

Seitz D, Shah PS, Herrmann N, Beyene J, Siddiqui N. General anesthesia and risk of Alzheimer’s disease: A systematic review and meta-analysis. BMC Geriatr. 2011;11(1):83.

Sgro M, Shah PS, Campbell D, Tenuta A, Shivananda S, Lee SK; Canadian Neonatal Network. Early-onset neonatal sepsis: rate and organism pattern between 2003 and 2008. J Perinatol. 2011;31(12):794-8.

Sgro M, Yudin MH, Lee S, Sankaran K, Tran D, Campbell D. Early-onset neonatal sepsis: It is not only group

B streptococcus. Paediatr Child Health. 2011;16(5):269.

Sgro M, Campbell D, Barozzino T, Shah V. Acute neurologic findings in a national cohort of neonates with severe neonatal hyperbilirubinemia. J Perinatol. 2011;31:392-6.

Shah PS, Balkhair T on behalf of the Knowledge Synthesis Group on determinants of preterm/LBW births. Air pollution and birth outcomes; a systematic review. Environ Int. 2011;37(2):498-516.

Shah PS, Balkhair T, Ohlsson A, Beyene J, Scott F, Frick C on behalf of Knowledge Synthesis Group on LBW/preterm birth. Intention to become pregnant and low birth weight and preterm birth: A systematic review. Mat Child Health J. 2011;15(2):205-16.

Shah PS, Dunn MS, Lee SK, Allen AC, Singhal N and the Canadian Neonatal Network. Early opioid infusion and neonatal outcomes in preterm neonates ≤28 weeks’ gestation. Am J Perinatol. 2011;28(5):361-6.

Shah PS, Kingdom J. Long-term neurocognitive outcomes of SGA/IUGR infants. Obstet Gynecol Reprod Med. 2011;21(5):142-6.

Shah PS, Ohlsson A. Sildenafil for pulmonary hypertension in neonates. Cochrane Database Syst Rev. 2011;8:CD005494.

Shah PS, Shah V. Propofol for procedural sedation in neonates. Cochrane Database Syst Rev. 2011;3:CD007248.

Shah PS, Zao J, Al-Wassia H, Shah V; Knowledge Synthesis Group on Determinants of Preterm/LBW Births. Pregnancy and neonatal outcomes of aboriginal women: a systematic review and meta-analysis. Womens Health Issues. 2011;21(1):28-39.

Shah PS, Zao J, Ali S, on behalf of Knowledge Synthesis Group on LBW/preterm birth. Maternal marital status and low birth weight and preterm birth: A systematic review. Matern Child Health J. 2011;15(7):1097-109.

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Shah VS, Al Wassia H, Shah K, Shah PS. Neonatal outcomes among multiple births < 32 weeks gestational age: Does mode of conception have an impact? BMC Paediatr. 2011;11:54.

Shah V, Chirinian N, Lee S, EPIQ Evidence Review Group. Does the use of glycerin laxatives decrease feeding intolerance in preterm infants? Pediatr Child Health. 2011;16(9):e68-70.

Srinivasjois R, Shah PS. Effect of induction of meconium evacuation using per rectal laxatives on neonatal hyperbilirubinemia in term Infants: a systematic review of randomized controlled studies. Indian J Med Sci. 2011;65(7):278-85.

Stevens B, Riahi S, Cardoso R, Ballantyne M, Yamada J, Beyene J, Breau L, Camfield C, Finley GA, Franck L, Gibbins S, Howlett A, McGrath PJ, McKeever P, O’Brien K, Ohlsson A. The influence of context on pain practices in the NICU: perceptions of health care professionals. Qual Health Res. 2011;21(6):757-770.

Stevens BJ, Abbott LK, Yamada J, Harrison D, Stinson J, Taddio A, Barwick M, Latimer M, Scott SD, Rashotte J, Campbell F, Finley GA, CIHR Team in Children’s Pain. Epidemiology and management of painful procedures in children in Canadian hospitals. CMAJ. 2011;183(7):E403-10.

Taddio A, Shah V, Stephens D, Parvez E, Hogan ME, Kikuta A. Koren G, Katz J. Effect of liposomal lidocaine, sucrose alone and in combination for venepuncture pain in newborns. Pediatrics. 2011;127(4):e940-7.

Teuffel O, Kuster SP, Hunger SP, Conter V, Hitzler J, Ethier MC, Shah PS, Beyene J, Sung L. Dexamethasone versus prednisone for induction therapy in childhood acute lymphoblastic leukemia: A systematic review and meta-analysis. Leukemia. 2011;25(8):1232-8.

Touma Z, Gladman DD, Urowitz M, Beyene J, Uleryk EM, Shah PS. Mycophenolate mofetil for induction treatment of lupus nephritis: A systematic review and meta-analysis. J Rheumatol. 2011;38(1):69-78.

Turner D, Zlotkin SH, Shah PS, Griffiths AM. Omega-3 fatty acids (fish oil) for maintenance of remission in inflammatory bowel disease: a systematic review and meta-analyses. Inflam Bowel Dis. 2011;17:336-45.

Unger S, Salem S, Wylie L, Shah V. Newborn Frontal Horn Cysts: Cause for Concern? J Perinatol. 2011;31(2):98-103.

van Wezel-Meijler G, Leijser LM, Wiggers-de Bruïne FT, Steggerda SJ, van der Grond J, Walther FJ. Diffuse hyperechogenicity of the basal ganglia and thalami in preterm infants: A physiological finding? Radiology. 2011: 258(3):944-50.

van Wezel-Meijler G, Wiggers-de Bruïne FT, Steggerda SJ, van den Berg-Huysmans AA, Zijlemaker S, Leijser LM, van der Grond J. Ultrasound detection of white matter injury in very preterm neonates: Practical implications. Dev Med Child Neurol. 2011:53(Suppl 4):29-34.

von Dadelszen P, Payne B, Li J, Ansermino JM, Broughton Pipkin F, Côté AM, Douglas MJ, Gruslin A, Hutcheon JA, Joseph KS, Kyle PM, Lee T, Loughna P, Menzies JM, Merialdi M, Millman AL, Moore MP, Moutquin JM, Ouellet AB, Smith GN, Walker JJ, Walley KR, Walters BN, Widmer M, Lee SK, Russell JA, Magee LA, PIERS Study Group. Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the full PIERS model. Lancet. 2011;377(9761):219-27.

Wiggers-de Bruïne FT, van Wezel-Meijler G, van den Berg-Huysmans AA, Leijser LM, van Steenis A, van Buchem MA, van der Grond J. Tractography of developing white matter in preterm born infants. Eur Radiol. 2011;21(3):538-47.

Yee WH, Scotland J, Pham Y, Finch R, EPIQ Evidence Review Team. Does the use of primary continuous positive airway pressure reduce the need for intubation and mechanical ventilation in infants ≤32 weeks’ gestation? Paediatr Child Health. 2011;16(10):633-7.

Zhang LR, Chiarelli AM, Glendon G, Mirea L, Edwards S, Knight JA, Andrulis IL, Ritvo P. Influence of perceived breast cancer risk on screening behaviors of female relatives from the Ontario site of the Breast Cancer Family Registry. Eur J Cancer Prev. 2011;20(4):255–62.

2010Al Wassia H, Shah PS. Folic acid supplementation for the prevention of neural tube defects: Promotion and use. Nutr Diet Suppl. 2010;2:105–16.

Asztalos EV, Murphy KE, Hannah ME, Willan AR, Matthews SG, Ohlsson A, Kelly EN, Saigal S, Ross S, Delisle MF, Amankwah K, Guselle P, Gafni A, Lee SK, Armson BA, Sananes R, Tomat L, Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study Collaborative Group. Multiple courses of antenatal corticosteroids for preterm birth study: 2-year outcomes. Pediatrics. 2010;126(5):e1045-55.

Azarpazhooh A,Shah PS, Tenenbaum H, Goldberg MB. Photodynamic therapy for periodontitis: a systematic review and meta-analysis. J Periodontol. 2010;81(1):4-14.

Bassil KL, Cole DC. Effectiveness of public health interventions in reducing morbidity and mortality during heat episodes: a structured review. Int J Environ Res Public Health. 2010;7(3):991-1001.

Bismilla Z, Finan E, Jefferies A, LeBlanc VR, McNamara P, Whyte H. Failure of paediatric and neonatal trainees to meet Canadian Neonatal Resuscitation Program standards for neonatal intubation. J Perinatology. 2010;30(3):182-7.


Bradley TJ, Potts JE, Lee SK, Potts MT, De Souza AM, Sandor GG. Early changes in the biophysical properties of the aorta in pre-adolescent children born small for gestational age. J Pediatr. 2010;156(3):388-92.

Brindle ME, Ma IW, Skarsgard ED, CPSN. Impact of target blood gases on outcome in congenital diaphragmatic hernia (CDH). Eur J Pediatr Surg. 2010;20(5):290-3.

Canadian Pediatric Society, Marchand V. Trans fats: What physicians should know. Pediatr Child Health. 2010;15(6):373-8.

Das A, Shah PS. Octreotide for the treatment of chylothorax in neonates. Cochrane Database Syst Rev. 2010;9:CD006388.

Dietitians of Canada, Canadian Pediatric Society, College of Family Physicians of Canada; Community Health Nurses of Canada, Secker D. Promoting optimal monitoring of child growth in Canada: using the new WHO growth charts. Can J Diet Pract Res. 2010;71(1):e1-3.

El-Naggar W, Yiu A, Mohamed A, Shah V, Manley J, McNamara P, Taddio A. Comparison of pain responses between two different methods of urine collection for diagnosis of infection in preterm infants. Paediatrics. 2010;125(6):1224-9.

Jefferies A, Skidmore M. Evaluation of a collaborative mentorship program in a multi-site postgraduate training program. Med Teach. 2010;32(8):695-7.

Jefferies A, Fetus and Newborn Committee, Canadian Paediatric Society. Retinopathy of prematurity: recommendations for screening. Paediatr Child Health. 2010;15(10):667–670.

Kim JH, Unger S. Human milk banking. Paediatr Child Health. 2010;15(9):595-8.

Lisonkova S, Janssen PA, Sheps SB, Lee SK, Dahlgren L. The effect of maternal age on adverse birth outcomes: does parity

matter? J Obstet Gynaecol Can. 2010;32(6):541-8.

McDonald SD, Han Z, Mulla S, Beyene J; Knowledge Synthesis Group. Overweight and obesity in mothers and risk of preterm birth and low birth weight infants: systematic review and meta-analyses. BMJ. 2010;341:c3428.

McDonald SD, Han Z, Mulla S, Murphy KE, Beyene J, Ohlsson A, on behalf of the Knowledge Synthesis Group on LBW/Preterm Birth. Preterm birth and low birth weight among in vitro fertilization twins: A systematic review and meta-analyses. Eur J Obstet Gynecol Reprod Biol. 2010;148(2):105-13.

Mills JL, Lin Y, MacNab YC, Skarsgard ED, CPSN. Does overnight birth influence treatment or outcome in congenital diaphragmatic hernia? Am J Perinatol. 2010;27(1):91-5.

Mills JA, Lin Y, Macnab YC, Skarsgard ED, CPSN. Perinatal predictors of outcome in gastroschisis. J Perinatol. 2010;30(12):809-13.

Mirea L, Sun L, Stafford JE, Bull SB. Using evidence for population stratification bias in combined individual- and family-level genetic association analyses of quantitative traits. Genet Epidemiol. 2011;34(5):502–11.

Nasef N, O’Brien K, Wylie L, Unger S. Lessons from SARS: A retrospective study of outpatient care during an infectious disease outbreak. BMC Pediatr. 2010;10:51.

Ostry A, Ogborn M, Bassil KL, Takaro TK, Allen DM. Climate change and health in british columbia: projected impacts and a proposed agenda for adaptation research and policy. Int J Environ Res Public Health. 2010;7(3):1018-35.

Parvez E, Stinson J, Boon H, Shah V, Taddio A. Mothers’ beliefs about analgesia during childhood immunization. Paediatr Child Health. 2010;15(5):289-93.

Proctor LK, Rushworth V, Shah PS, Keunen J, Windrim R, Ryan G, Kingdom J. Under-estimation of fetal weight in asymmetric preterm growth restriction by incorporation of femur length. Ultrasound Obstet Gynecol. 2010;35(4):442-8.

Safavi A, Lin Y, Skarsgard ED, CPSN. Perinatal management of congenital diaphragmatic hernia: when and how should babies be delivered? Results from the Canadian Pediatric Surgery Network. J Pediatr Surg. 2010;45(12):2334-9.

Salmasi G, Grady R, Jones J, Mcdonald SD on behalf of the knowledge synthesis group. Environmental tobacco smoke exposure and perinatal outcomes: a systematic review and meta-analyses. Acta Obstet Gynecol Scand. 2010;89(4):423-41.

Sehgal A, Mak W, Dunn M, Kelly E, Whyte H, McCrindle B, McNamara PJ: Haemodynamic changes after delivery room surfactant administration to very low birth weight infants. Arch Dis Child Fetal Neonatal Ed. 2010;95(5):F345-51.

Shah PS, on behalf of the Knowledge Synthesis Group on determinants of LBW/preterm birth. Parity and low birth weight and preterm birth: A systematic review. Acta Obstet Gynecol Scand. 2010;89(7):862-75.

Shah PS, on behalf of the Knowledge Synthesis Group on LBW/preterm birth. Paternal factors and low birth weight and preterm birth: A systematic review. Am J Obstet Gynecol. 2010;202(2):103-23.

Shah PS, Shah J, on behalf of the Knowledge Synthesis Group on LBW/preterm birth. Maternal exposure to domestic violence and pregnancy and birth outcomes: a systematic review and meta-analyses. J Women’s Health (Larchmt). 2010;19(11):2017-31.

Shah PS. Hypothermia: a systematic review and meta-analysis of clinical trials. Semin Fetal Neonatal Med. 2010;15(5):238-46.

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Shah PS. Micronutrients and pregnancy outcomes: Implications and challenges. The Female Patient. 2010;35(7):32-4.

Soylu H, Jefferies A, Diambomba Y, Windrim R, Shah PS. Rupture of membranes before the age of viability: comparison of outcomes in a matched cohort study. J Perinatology. 2010;30(10):645-9.

Stevens B, McGrath P, Ballantyne M, Yamada J, Dupuis A, Gibbins S, Franck L, Allen Finley G, Howlett A, Johnston C, O’Brien K, Ohlsson A. Influence of risk of neurological impairment and procedure invasiveness on health professionals’ management of procedural pain in neonates. Eur J Pain. 2010;14(7):735-741.

Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V. Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline (summary). CMAJ. 2010;182(18):1989-95.

Taddio A, Appleton M, Bortolussi R, Chambers C, Dubey V, Halperin S, Hanrahan A, Ipp M, Lockett D, MacDonald N, Midmer D, Mousmanis P, Palda V, Pielak K, Riddell RP, Rieder M, Scott J, Shah V. Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline. CMAJ. 2010;182(18):E843-55.

Taddio A, Pulleyblank R, Stephens D, McNair C, Shah V. Canadian neonatologists practices regarding opioid use in ventilated and spontaneously-breathing infants undergoing medical procedures. Clin J Pain. 2010;26(5):422-8.

Unger S, Wylie L, Fallah S, Heinrich L, O’Brien K. Motivated by money? The impact of financial incentive for the research team on study recruitment. IRB. 2010;32(1):16-19.

von Dadelszen P , Sawchuck D , McMaster R , Douglas MJ , Lee

SK , Saunders S , Liston RM , Magee LA , TESS Group. The active implementation of pregnancy hypertension guidelines in British Columbia. Obstet Gynecol. 2010;116(3):659-66.

Weinmann A, Post M, Pan J, Rafii M, O’Connor D, Unger S, Pencharz P, Belik J. Tetrahydrobiopterin is present in high quantity in human milk and has a vasorelaxing effect on newborn rat mesenteric arteries. Pediatr Res. 2010;69(4):325-9.

Wieczorek PM, Guest S, Balki M, Shah V, Carvalho JCA. Breast feeding success rate after vaginal delivery can be high despite the use of epidural fentanyl: an observational cohort study. Int J Obstet Anesth. 2010;19(3):273-7.

Yinon Y, Visser J MD, Kelly EN MB, Windrim R MD, Amsalem H MD, Seaward PG MB, Ryan G MB: Early intra-uterine transfusions in severe red blood cell alloimmunization. Ultrasound Obstet Gynecol. 2010;36(5):601-6.

Yinon Y, Grisaru-Granovsky S, Chadda V, Windrim R, Seaward GR, Kelly EN, Beresovska O, Ryan G: Perinatal outcome following fetal chest shunt insertion for pleural effusions. Ultrasound Obstet Gynecol. 2010;36(1):58–64.

Yinon Y, Kingdom JC, Proctor LK, Kelly EN, Salle JL, Wherrett D, Keating S, Nevo O, Chitayat D. Hypospadias in males with intrauterine growth restriction due to placental insufficiency: the placental role in the embryogenesis of male external genitalia. Am J Med Genet A. 2010.;152A(1):75-83.

2009Aimone A, Vaughan J, Ward W, Jefferies A, Campbell D, Asztalos E, Feldman M, Rovet J, Westall C, Whyte H, O’Connor DL. Growth and body composition of human milk-fed premature infants provided with extra energy and nutrients early after hospital discharge: One year follow-up. J Pediatr Gastroenterol Nutr. 2009;49(4):456-66.

Al-Jewair TS, Azarpazhooh A, Suri S, Shah PS. Computer-assisted learning in orthodontic education: A systematic review and meta-analyses. J Dental Educ. 2009;73(6):730-9.

Boutros J, Regier M, Skarsgard ED, CPSN. Is timing everything? The influence of gestational age, birth weight, route, and intent of delivery on outcome in gastroschisis. J Pediatr Surg. 2009;44(5):912-7.

Chambers CT, Taddio A, Uman LS, McMurtry CM; HELPinKIDS Team. Psychological interventions for reducing pain and distress during routine childhood immunizations: a systematic review. Clin Ther. 2009;31(Suppl 2):S77-103.

Cheng SS, Forte V, Shah VS. Symptomatic congenital vallecular cyst in a neonate. J Pediatr. 2009;155(3):446.

El-Khuffash A, Molloy EJ. The use of N-terminal-Pro-BNP (NTpBNP) in preterm infants. [Epub Dec 30, 2009] Int J Pediatr. doi: 10.1155/2009/175216.

Fergusson D, Hutton B, Hogan DL, LeBel L, Blajchman MA, Ford JC, Hebert P, Kakadekar A, Kovacs L, Lee S, Sankaran K, Shapiro S, Smyth JA, Ramesh K, Bouali NR, Tinmouth A, Walker R. The age of red blood cells in premature infants (ARIPI) randomized controlled trial: study design. Transfus Med Rev. 2009;23(1):55-61.

France CR, Taddio A, Shah V, Page G, Katz J. Maternal family history of hypertension attenuates neonatal pain response. Pain. 2009;142(3):189-93.

Godambe SV, Parvez B, Ein SH, Shah V. An asymptomatic presentation of gastric outlet obstruction secondary to congenital antral web in an extremely preterm infant. [Epub 14 Dec, 2009] BMJ Case Rep. doi: 10.1136/bcr.10.2009.2327.

Graham S, Shah PS, Von Aesch Z, Beyene J, Bayoumi A. A systematic review of trials evaluating biomedical HIV prevention


interventions Shows that many lack power. HIV Clin Trials. 2009;10(5):413-31.

Grushka JR, Laberge JM, Puligandla P, Skarsgard ED, CPSN. Effect of hospital case volume on outcome in congenital diaphragmatic hernia: the experience of the Canadian Pediatric Surgery Network. J Pediatr Surg. 2009;44(5):873-6.

Jain A, Kelly E, Shah V. Parvovirus B19 Infection in pregnancy: Implications for childhood outcomes? Open Infect Dis J. 2009;3(1):83–93.

Jakobson LS, Frisk V, Trachsel D, O’Brien K. Visual and fine-motor outcomes in adolescent survivors of high-risk congenital diaphragmatic hernia who did not receive extracorporeal membrane oxygenation. J Perinatol. 2009;29(9):630-6.

James AG, Eugene N, Shah PS. A reference set of SNOMED terms for the structured representation of respiratory disorders of the newborn infant. Stud Health Technol Inform. 2009;150:243-7.

Janssen PA, Saxell L, Page LA, Klein MC, Liston RM, Lee SK. Outcomes of planned home birth with registered midwife versus planned hospital birth with midwife or physician. CMAJ. 2009;181(6-7):377-83.

Johnson N, Shah PS, Shannon P, Campisi P, Windrim R. A challenging delivery by EXIT procedure of a fetus with a giant cervical teratoma. J Obstet Gynaecol Can. 2009;31(3):267-71.

Joseph KS, Fahey J, Platt RW, Liston RM, Lee SK, Sauve R, Liu S, Allen AC, Kramer MS. An outcome-based approach for the creation of fetal growth standards: do singletons and twins need separate standards? Am J Epidemiol. 2009;169(5):616-24.

Kwan D, Beyene J, Shah PS. Adverse consequences

of internet purchase of pharmacological agents or dietary supplements. J Pharm Technol. 2009;25:355-60.

Lee SK, Aziz K, Singhal N , Cronin CM , James A , Lee DS , Matthew D , Ohlsson A , Sankaran K , Seshia M, Synnes A , Walker R , Whyte R , Langley J , MacNab YC , Stevens B , von Dadelszen P. Improving the quality of care for infants: a cluster randomized controlled trial. CMAJ. 2009;181(8):469-76.

Liu J , Morton J , Miedzyblocki M , Lee TF , Bigam DL , Fok TF , Chen C , Lee SK , Davidge ST , Cheung PY. Sodium tanshinone IIA sulfonate increased intestinal hemodynamics without systemic circulatory changes in healthy newborn piglets. Am J Physiol Heart Circ Physiol. 2009;297(4):H1217-24.

Lodha A, Hellmann J, Shah PS. Pulmonary hemorrhage associated with preceding neurological insult in neonates. Heart Lung Circ. 2009;18(a):45-8.

Massey KA , Magee LA , Dale S , Claydon J , Morris TJ , von Dadelszen P , Liston RM , Ansermino JM , CPNC Group, British Columbia Perinatal Health Program. A current landscape of provincial perinatal data collection in Canada. J Obstet Gynaecol Can. 2009;31(3): 236-46.

McDonald SD, Han Z, Mulla S, Murphy KE, Beyene J, Ohlsson A, on behalf of the knowledge synthesis group on LBW/Preterm Birth. Preterm birth and low birth weight among in vitro fertilization singletons: A systematic review and meta-analyses. Eur J Obstet Gynecol Reprod Biol. 2009;146(2):138-48.

Molloy EJ, El-Khuffash A, Bieda A, Jelinek MM, Baley J. Elevated Iron Indices in Pre Term Infants: Association with Male Gender. Am J Perinatol. 2009;26(1):7-11.

Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal group B streptococcal colonization. Cochrane Database Syst Rev. 2009;3:CD007467.

Perlman M, Shah PS. Ethics of therapeutic hypothermia. Acta Paediatr. 2009;98(2):211-3.

Pringsheim T, O’Connor P, Shah PS, Sandor P. Prenatal and perinatal morbidity in children with Tourette syndrome and attention deficit hyperactivity disorder: A nested case control study. J Dev Behav Pediatr. 2009;30(2):115-21.

Robinson JL, Davies HD, Barton M, O’Brien K, Simpson K, Asztalos E, Synnes A, Rubin E, Le Saux N, Hui C, Langley JM, Sauve R, De Repentigny L, Kovacs L, Tan B, Richardson SE. Characteristics and outcome of infants with candiduria in neonatal intensive care – a Pediatric Investigators Collaborative Network on Infections in Canada (PINIC) study. BMC Infec Dis. 2009;9:183.

Roggensack A, Jefferies AL, Farine D, Basso M, Delisle MF, Hudon L, Mundle WR, Murphy-Kaulbeck LC, Ouellet A, Pressey T. Management of meconium at birth. J Obstet Gynaecol Can. 2009;31(4):353-4.

Shah PS, Kaufman D. Antistaphylococcal immunoglobulins to prevent staphylococcal infection in very low birth weight infants. Cochrane Database of Syst Rev. 2009;2:CD006449.

Shah PS, Ohlsson A; Knowledge Synthesis Group on Determinants of Low Birth Weight and Preterm births. Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysis. CMAJ. 2009;180(12):E99-108.

Shah PS, Perlman M. Time course of intrapartum asphyxia: neonatal characteristics and

9510-Year Report

outcome. Am J Perinatol. 2009;26(1):39-44.

Shah PS, Shah P, Young Tai KF. Chest compression and/or epinephrine at birth for preterm infants <32 weeks gestational age: matched cohort study of neonatal outcomes. J Perinatol. 2009;29(10):693-7.

Shah PS, Shah V on behalf of Knowledge Synthesis Group on LBW/preterm birth. Influence of maternal birth status on subsequent low birth weight and preterm birth: A systematic review. Acta Obstet Gynecol Scand. 2009;88(12):1307-18.

Shah PS, Zao J; Knowledge Synthesis Group on Determinants of Preterm/LBW births. Induced termination of pregnancy and low birthweight and preterm birth: a systematic review and meta-analyses. BJOG. 2009;116(11):1425-42.

Shah PS. Extensive cardiopulmonary resuscitation for VLBW and ELBW infants: A systematic review and meta-analyses. J Perinatol. 2009;29(10):655-61.

Shah V, Beyene J, Shah P, Perlman M. Association between hematologic findings and brain injury due to neonatal hypoxic-ischemic encephalopathy. Am J Perinatol. 2009;26(4):295-302.

Shah V, Taddio A, Rieder MJ; HELPinKIDS Team. Effectiveness and tolerability of pharmacologic and combined interventions for reducing injection pain during routine childhood immunizations: systematic review and meta-analyses. Clin Ther. 2009;31(Suppl 2):S104-51.

Soraisham AS, Singhal N, McMillan DD, Sauve RS, Lee SK, CNN. A multicenter study on the clinical outcome of chorioamnionitis in preterm infants. Am J Obstet Gynecol. 2009;200(4):372.e1-6.

Stevens B, McGrath P, Dupuis A, Gibbins S, Beyene J, Breau L, Camfield C, Finley GA, Franck

LS, Howlett A, Johnston C, McKeever P, O’Brien K, Ohlsson A, Yamada J. Indicators of pain in neonates at risk for neurological impairment. J Adv Nurs. 2009;65(2):285-296.

Taddio A, Chambers CT, Halperin SA, Ipp M, Lockett D, Rieder MJ, Shah V; HELPinKIDS Team. Inadequate pain management during routine childhood immunizations: the nerve of it. Clin Ther. 2009;31(Suppl 2):S152-67.

Taddio A, Crosdale B, Hogan ME, El Sayed M, Lee KS, Moore AM, Shah V. Safety of morphine in non-intubated infants in the neonatal intensive care unit. Clin J Pain. 2009;25(5):418-22.

Taddio A, Ilersich AL, Ipp M, Kikuta A, Shah V; HELPinKIDS Team. Physical interventions and injection techniques for reducing injection pain during routine childhood. Clin Ther. 2009;31(Suppl 2):S48-76. Taddio A, Shah V, Atenafu E, Katz J. Influence of repeated painful procedures and sucrose analgesia on the development of hyperalgesia in newborn infants. Pain. 2009;144(1-2):43-8.

Taddio A, Shah V, Katz J. Reduced infant response to a routine care procedure after sucrose analgesia. Paediatrics. 2009;123(3):e425-9.

Taddio A, Yiu A, Smith RW, Katz J, McNair C, Shah V. Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful procedures. Clin J Pain. 2009;25(2):153-5.

Jain A, Godambe S, Clarke S, Chow P. Unusually late presentation of lactobezoar leading to necrotizing enterocolitis in an extremely low birthweight infant. [Epub Jul 26, 2009] BMJ Case Rep. doi: 10.1136/bcr03.2009.1708.

von Dadelszen P, Menzies JM, Payne B, Magee LA, PIERS Study Group. Predicting adverse outcomes in women with severe pre-eclampsia. Semin Perinatol. 2009;33(3):152-7.

Williams C, Cairnie J, Fines V, Patey C, Schwarzwer K, Aylwaard J, Lohfeld L, Kirpalani H. Construction of a parent-derived questionnaire to measure end-of-life care after withdrawal of life-sustaining treatment in the neonatal intensive care unit. Pediatrics. 2009 Jan: 123(1):e87-95.

DEPARTMENT OF PAEDIATRICS

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DEPARTMENT OF PAEDIATRICS...10-Year Report 5 It has been a pleasure for me to serve as Paediatrician-in-Chief of the Department of Paediatrics at Mount Sinai Hospital, part of Sinai