Curetis GmbH Max-Eyth-Str. 42 | 71088 Holzgerlingen | GermanyTel.: +49 (0)7031 49195 65 | Email: pharma@curetis.com

Ares Genetics GmbH Karl-Farkas-Gasse 18 | 1030 Vienna | AustriaTel.: +43 (0)1 361 8880 | Email: pharma@ares-genetics.com

We offer a comprehensive portfolio of solutions for antimicrobial drug discovery, clinical development, and product lifecycle management. Our solutions aim at supporting data-driven target and lead prioritization, accelerating clinical trials, augmenting clinical data for regulatory submissions, and informed antimicrobial drug use for effective antibiotic stewardship post launch.

Your partner for antimicrobial drug development

Next Level Solutions for Molecular Microbiology & Data Intelligence in Antimicrobial Drug Development

Member of ABx DevelopmentInforming

Accelerate R&D

Augment Clinical Data

Prescribe Effectively

www.curetis.com

www.ares-genetics.com

00605 Rev. 1.0 © Curetis GmbH

Caution – Investigational Device. Limited by Federal US Law to investigational Use. Not available for Sale in the United States.

Advanced Bioinformatics and Artificial Intelligence for AMR

AMR Target ID and MoA studies

Lead compound prioritization

AMR prediction at molecular level

Deep pathogen characterization in discovery, clinical development, and surveillance

The world’s most comprehensive database on the genetics of antimicrobial resistance

24/7 molecular testing

In any lab or at point-of-care

Results in 1-4 hours

Comprehensive off-the-shelf panels

Customized panels tailored to drug

The any-plex solution for detection of pathogens and genetic antimicrobial resistance markers

Rapid molecular diagnostics for clinical trials and LCM

1 A30 RQ Analzyer in development. Design concept. Actual product may differ.

ARES Technology Platform

Molecular microbiology data intelligence

L4 C8 A50 A30 RQ1

Preclinical Clinical Trials Product Lifecycle Management

Target and MoA Analysis Customized in silico target characterization, epidemiology, and MoA analysis.

Lead Prioritization In vitro high throughput resistance testing combined with customized in silico data analysis solutions to predict likelihood and mechanisms of resistance.

MDx Development

Advanced in silico tools combined with profound experience in molecular microbiology

assay design for clinical trial and companion diagnostic use.

ABx Research and Discovery

Deep Pathogen Characterization

Deep profiling of pathogens using whole genome sequencing to enrich clinical trial data for regulatory submissions.

Optimized Enrolment Customized and off-the-shelf multipex PCR panels for pathogens and resistance

markers enabling rapid, and targeted clinical trial enrolment.

POC HospitalLab

CentralLab

Companion DiagnosticsCustomized multiplex PCR panels for rapid diagnostics

and informed treatment decisions.

Molecular EpidemiologyPost-market surveillance, resistance evolution

monitoring and services.

Streamlined trials and enriched trial datareduce development costs

Increased revenues

Improved product lifecycleFast-tracked development

Informed decisions by data-driven target and lead selection and validation

Biomarker DiscoveryIdentification, validation and epidemiological assessment of ABx drug-specific

biomarkers for clinical trials and companion diagnsotics.