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    Unit 2 Study Guide Part A

    2010

    Growth and Reproduction

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    What and How to Study

    Study the PowerPoint lectures and their review

    questions.

    Read the chapters assigned in the text.

    Know the key vocabulary terms (lists at the end

    of each chapter and/or the glossaries).

    Prepare frequently prior to the test. Review the

    film study questions where applicable.These statements apply to all of the unit tests

    and exam.

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    Please Note

    The study guide question project is a work

    in progress, and accordingly, it is

    incomplete. Therefore none of the studyquestion sets should be considered a

    substitute for a complete and exhaustive

    test preparation. This applies to all four of

    the study guide question sets.

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    Mitosis

    Study Guide Questions

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    Q 1

    Define the word reproduction.

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    A 1

    The production of a new generation of

    cells or a multi-cellular organism

    similar to itself.

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    Q 2

    Mitosis and meiosis refer to the division of

    the cell's __________.

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    A 2

    Mitosis and meiosis refer to the division of

    the cell's __nucleus (DNA)________.

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    Q 3

    Distinguish between somatic cells and

    germ cells as to their location and function.

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    A 3

    Distinguish between somatic cells and

    germ cells as to their location and function.

    Somatic cells are body site of mitosis

    (2n); Immature reproductive cells (site

    of meiosis)

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    Q 4

    The eukaryotic chromosome is composed

    of __________ and __________.

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    A 4

    The eukaryotic chromosome is composed

    of __DNA________ and

    __Proteins________.

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    Q 5

    The two attached threads of a duplicated

    chromosome are known as sister

    __________.

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    Q 6

    Characterize the organization of

    chromosomes using the terms histones

    and nucleosome.

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    A 6

    Characterize the organization of

    chromosomes using the terms histones

    and nucleosome.At reg. intervals

    double stranded DNA is wrapped

    around proteins called histones; DNA-

    histone spools look like beads on a

    string. Each bead is a nucleosome.

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    Q 7

    The __________ is a small region with

    docking sites for the microtubules with

    roles in nuclear division.

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    A 7

    The ____centromere______ is a small

    region with docking sites for the

    microtubules with roles in nuclear division.

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    Q 8

    Each species has a characteristic

    __________ number, the sum total in cells

    of a given type.

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    A 8

    chromosome

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    Q 9

    Any cell having two of each type of

    chromosome characteristic of a species is

    a __________ cell; eggs and sperms of

    such organisms have only one of each

    type of chromosome and are said to be

    __________

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    A 9

    Any cell having two of each type of

    chromosome characteristic of a species is

    a ___diploid_______ cell; eggs and

    sperms of such organisms have only one

    of each type of chromosome and are said

    to be _haploid_________

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    Q 10

    Interphase of the cell cycle consists of G1,

    __________, and G2.

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    A 10

    Interphase of the cell cycle consists of G1,

    ____S______, and G2.

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    Q 11

    Describe the structure and function of the

    spindle apparatus.

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    A 11

    Describe the structure and function of the spindle apparatus.

    The spindle apparatus moves the chromosomes.

    The spindle apparatus is composed of two sets ofmicrotubules.

    Microtubules (components of the cytoskeleton) extend

    from the two poles of the cell and overlap at the cell equator. Microtubules are composed of numerous subunits called

    tubulins.

    Some microtubules extend from the centromeres to one ofthe two poles; others extend from the poles, overlap in themiddle of the cell, but do not contact the chromosomes.

    Microtubules attached to the centromeres shorten and pull thechromosomes toward the poles.

    Other microtubules at the spindle poles ratchet past eachother to push the two spindle poles apart.

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    Q12

    Describe the number and movements of

    centrioles in the cell division of some cells.

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    A 12

    Describe the number and movements of

    centrioles in the cell division of some cells.

    The centrioles, which have duplicated

    by the time prophase is underway, are

    moved by the microtubules to the

    opposite poles of the cell.

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    Q 13

    The "__________" is a time of transition

    when the nuclear envelope breaks up into

    tiny, flattened vesicles prior to metaphase.

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    A 13

    The "__prophase________" is a time of

    transition when the nuclear envelope

    breaks up into tiny, flattened vesicles prior

    to metaphase.

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    Q 14

    Be able to give a detailed description of

    the cellular events occurring in the

    prophase, metaphase, anaphase, and

    telophase of mitosis.

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    A 14.1

    A. Prophase: Mitosis Begins

    1. Chromosomes becomevisible as rodlike units, each consisting of two sisterchromatids.

    2. In the cytoplasm, themicrotubules of the cytoskeleton break apart andbegin reassembling near the nucleus.

    a. Microtubules arecomposed of numerous subunits called tubulins.

    b.S

    ome microtubulesextend from the centromeres to one of the two poles;others extend from the poles, overlap in the middleof the cell, but do not contact the chromosomes.

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    A 14.2

    3. The nuclear envelope begins to

    disintegrate.

    4. The centrioles, whichhave duplicated by the time prophase

    is underway, are now moved by the

    microtubules to the opposite poles of

    the cell

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    A 14.3

    B. Transition to Metaphase

    1. The nuclear membranenow breaks up completely in the transitionbetween pro- and metaphase.

    2. Sister chromatids, eachattached to microtubules, become orientedtoward opposite poles.

    3. When all the

    chromosomes are aligned at the cellsequator, halfway between the poles, we callthe stage metaphase.

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    A 14.4

    C. From Anaphase Through Telophase

    1. Sister chromatids separateand move toward opposite poles.

    a. Microtubules attachedto the centromeres shorten and pull thechromosomes toward the poles.

    b. Other microtubules atthe spindle poles ratchetpast each other to push thetwo spindle poles apart.

    c. Once separated, eachchromatid is now an independent chromosome.

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    A 14.5

    2. Telophase begins when thetwo daughter chromosomes of each originalchromatid pair arrive at opposite poles.

    a. Chromosomesreturn to the threadlike form typical ofinterphase.

    b. The nuclear envelope reforms from the fusion of small

    vesicles c. Each daughter cellhas the same number of chromosomes asthe parent cell; mitosis is complete.

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    Q 15

    Compare and contrast cytokinesis as it

    occurs in plant and animal cell division;

    use the following concepts: cleavage

    furrow, microfilaments at the cell's

    midsection, and cell plate formation.

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    A 15.1

    A. Cell Plate Formation inPlants

    1. Because of the rather

    rigid cell wall, the cytoplasm of plantcells cannot just be pinched in two.

    2. Instead vesicles

    containing remnants of themicrotubular spindle form a disklikestructure during cell plate formation.

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    A 15.2

    B. Cytoplasmic Division ofAnimal

    Cells

    1. The flexible plasmamembrane of animal cells can be

    squeezed in the middle to separate the

    two daughter cellsa process called

    cleavage.

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    A 15.3

    Parallel arrays of contractile

    microfilaments slide past one another

    at the cleavage furrow, pulling the

    plasma membrane inward.

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    Q 16

    Explain how cells from Henrietta Lacks

    continue to benefit humans everywhere

    more than forty years after her death.

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    A 16

    Explain how cells from Henrietta Lacks

    continue to benefit humans everywhere

    more than forty years after her death.

    Her cells live on in the cell biology

    laboratories of the world where they

    help cellular biologists understand cell

    division, both normal and abnormal.

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    Meiosis

    Study Guide Questions

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    Q 1

    Distinguish between germ cells and

    gametes.

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    A 1

    Germ cells are 2n while gametes are n

    (haploid). Germ cells produce gametes.

    Gametes fuse to form a zygote.

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    Q 2

    1. "One parent alone produces offspring,

    and each offspring inherits the same

    number and kinds of genes as its parent"

    describes __________ reproduction.

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    Q 2

    asexual

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    Qs 3, 4, and 5

    __________ reproduction involves meiosis,

    gamete formation, and fertilization.

    __________ divides chromosomes into

    separate parcels not once but twice prior tocell division.

    Describe the relationship between the

    following terms: homologous chromosomes,

    diploid number, and haploid number.

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    As 3, 4, and 5

    Sexual; Meiosis

    Homologous chromosomes line - up (evenunequally matched sex chromosomes!)

    during meiosis. These homologous chromosomes are in

    pairs so that each nucleus is diploid prior toanaphase I of meiosis.

    After anaphase I, the resulting daughternuclei are haploid (having only one of eachtype of chromosome).

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    Qs 6, 7, and 8

    If the diploid chromosome number for aparticular plant species is 18, the haploidgamete number is __________.

    During interphase a germ cell duplicates itsDNA; a duplicated chromosome consists oftwo DNA molecules that remain attached to aconstriction called the __________.

    As long as the two DNA molecules remainattached, they are referred to as ____________________ of the chromosome.

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    As 6, 7, and 8

    9

    centromere

    sister chromatids

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    Qs 9, 10, and 11

    During meiosis I, homologous

    chromosomes pair; each homologue

    consists of __________ chromatids.

    During meiosis II, the two sister

    __________ of each __________ are

    separated from each other.

    Interphase of the cell cycle consists ofG1, __________, and G2..

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    As 9, 10 and, 11

    two

    chromatids; chromosome

    S

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    Qs 12 and 13

    The __________ attachment andsubsequent positioning of each pair ofmaternal and paternal chromosomes at

    metaphase I lead to different__________ of maternal and paternaltraits in each generation of offspring.

    Meiosis in the animal life cycle results inhaploid __________; meiosis in the plantlife cycle results in haploid __________.

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    As 12 and 13

    random; combinations

    gametes; gametophytes

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    Q 14

    Using the special terms for the cells at the

    various stages, describe spermatogenesis

    in male animals and oogenesis in female

    animals

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    A 14.1

    Gamete Formation in Animals

    1. The life cycle of multicelledanimals proceeds from meiosis to gamete formation>>> fertilization >>> growth by mitosis.

    2. In males, meiosis and gameteformation are called spermatogenesis.

    a. Germ cell (2n) >>>primary spermatocyte (2n) >>> MEIOSIS I >>> twosecondary spermatocytes (n) >>> MEIOSIS II >>>four spermatids (n). b. Spermatids change inform; each develops a tail to become mature sperm.

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    A 14.2

    3. In females, meiosis and gamete formationare called oogenesis.

    a. Germ cell (2n) >>>

    primary oocyte (2n) >>> MEIOS

    IS

    I >>>secondary oocyte (n, and large in size) pluspolar body (n, and small in size) >>> MEIOSISII >>> one large ovum (n) plus three polarbodies (n, small).

    b. The single ovum isthe only cell capable of being fertilized by asperm; the polar bodies wither and die.

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    Qs 15 and 16

    Crossing over, the distribution of randommixes of homologous chromosomes intogametes, and fertilization contribute to

    __________ in the traits of offspring. Mitotic cell division produces only

    __________; meiotic cell division, inconjunction with subsequent fertilization,promotes __________ in traits amongoffspring.

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    As 15 and 16

    variation

    identical cells, variation

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    Q 17

    1. Be able to list three ways that meiosis

    promotes variation in offspring.

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    A 17

    The variation present at fertilization is fromthree sources:

    a. Crossing over occurs during prophase I.

    b. Random alignmentsat metaphase I lead to millions ofcombinations of maternal and paternalchromosomes in each gamete.

    c.O

    f all the geneticallydiverse gametes produced, chance willdetermine which two will meet.

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    The End of Unit 2 Part A Study

    Guide