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Relation Between Estimated Cardiorespiratory Fitness and Running Performance in Free- Living: an Analysis of HRV4Training Data International Conference on Biomedical and Health Informatics. Orlando, 2017 HRV4Training.com Marco Altini, Chris Van Hoof and Oliver Amft

Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

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Page 1: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

Relation Between Estimated Cardiorespiratory Fitness and Running Performance in Free-Living: an Analysis of HRV4Training Data

International Conference on Biomedical and Health Informatics. Orlando, 2017!

HRV4Training.com!

Marco Altini, Chris Van Hoof and Oliver Amft!

Page 2: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

2!

MEASURING BEHAVIOR VS MEASURING HEALTH & PERFORMANCE

BHI, 2017! HRV4Training.com!

Research as well as consumer products have been mainly focusing on measuring behavior (steps, calories, activities performed, etc.)!!!These approaches have limitations, behavioral aspects are important (what we do) but to implement effective interventions and provide relevant feedback we should quantify changes in our health and performance (potentially resulting from behavioral interventions)!

Page 3: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

3!

HOW DO WE QUANTIFY HEALTH AND PERFORMANCE?

BHI, 2017!

Cardiorespiratory fitness is a key health parameter and performance indicator in endurance sports!It refers to the ability of the cardiorespiratory system to provide oxygen to muscles during physical activity!!Regular exercise improves these processes (bigger heart muscle which reflects into more blood being pumped with each beat, more arteries in trained skeletal muscles, etc.)!

HRV4Training.com!

Page 4: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

4!

HOW DO WE MEASURE CARDIORESPIRATORY FITNESS?

BHI, 2017! HRV4Training.com!

VO2max tests: gold standard, maximal oxygen uptake during incremental exercise!!Impractical: infrastructure and personnel required!!Submaximal tests: limited effort, typically still require a certain exercise to be performed (e.g. run at a certain intensity)! !

Page 5: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

5!

SUBMAXIMAL AND NON-EXERCISE TESTS

BHI, 2017! HRV4Training.com!

Recent developments showed that VO2max can be estimated with good accuracy during activities of daily living!!However, we typically stop here ! !

Page 6: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

6!

SUBMAXIMAL AND NON-EXERCISE TESTS

BHI, 2017! HRV4Training.com!

Recent developments showed that VO2max can be estimated with good accuracy during activities of daily living!!However, we typically stop here ! !Many questions remain unanswered. Is the sub-maximal estimate sufficiently accurate? What does it mean in practical terms? Can we use estimated VO2max as a proxy of performance? How do we validate the usefulness and practical applicability of our estimates? !

Page 7: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

7!

BHI, 2017! HRV4Training.com!

1.  Build VO2max estimation models relying on data that can be acquired in free-living without specific protocols: no effort required on the subject/user side. Validate these models in the lab.!

2.  Deploy VO2max estimation models in free-living on a large set of study participants (500+)!

3.  Collect reference data related to human performance to evaluate the relation between performance and estimated VO2max and determine it’s usefulness in unsupervised free-living settings

OUR APPROACH

Page 8: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

8!

1. BUILD VO2MAX ESTIMATION MODELS

BHI, 2017! HRV4Training.com!

48 participants (22 male, 26 female), ECG and indirect calorimetry were acquired while running at different speeds and during a VO2max test on a cycle ergometer. To keep speed unconstrained we included as predictor the running speed to heart rate ratio in our VO2max estimation model

●●

●●

●●

R=0.72

30

40

50

60

30 40 50 60Predicted VO2max

Ref

eren

ce V

O2m

ax

Gender●

FemaleMale

Anth − VO2max (ml/kg/min)

●●

●●

●●

R=0.72

30

40

50

60

30 40 50 60Predicted VO2max

Ref

eren

ce V

O2m

ax

Resting − VO2max (ml/kg/min)

●●

●●

●●

R=0.8

30

40

50

60

30 40 50 60Predicted VO2max

Ref

eren

ce V

O2m

ax

Training − VO2max (ml/kg/min)

●●

●●

●●

●●

●●

●●

−20

0

20

30 35 40 45 50 55Mean, (Reference + Fitted)/2

Res

idua

ls

Bland−Altman − Anth − VO2max (ml/kg/min)

●●

●●

●●

●●

●●

●●

●●

−20

0

20

30 35 40 45 50 55Mean, (Reference + Fitted)/2

Res

idua

ls

Bland−Altman − Resting − VO2max (ml/kg/min)

●●

●●

●●

●●●

●●

● ●

−20

0

20

30 40 50Mean, (Reference + Fitted)/2

Res

idua

ls

Bland−Altman − Training − VO2max (ml/kg/min)

Page 9: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

9!

2. DEPLOY VO2MAX ESTIMATION MODELS

BHI, 2017! HRV4Training.com!

HRV4Training app: spot check for resting physiological data (heart rate, heart rate variability). Camera based, low cost, low barrier. Currently 14K+ users!!Training data: HRV4Training links to Strava and can collect workouts data (running pace, speed, heart rate, etc.)!Models built in the lab were deployed to users meeting certain criteria (app link to Strava, training with a heart rate monitor, 6 weeks of data and 12 workouts available)

Page 10: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

10!

BHI, 2017! HRV4Training.com!

Real life running performance was determined as the best time over “standard” running distances, such as the 10km, half marathon and full marathon. Running times were acquired from HRV4Training via the Strava integration over a period of one to 8 months!Runners were also clustered in categories based on running time over the three distances (fast, average, slow)!!!!!

3. COLLECT REFERENCE DATA

Page 11: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

11!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Page 12: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

12!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Page 13: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

13!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Page 14: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

14!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Moderate to strong correlation for all running distances (r = 0.56-0.61)

Page 15: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

15!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Moderate to strong correlation for all running distances (r = 0.56-0.61)

Page 16: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

16!

BHI, 2017! HRV4Training.com!

RELATION BETWEEN ESTIMATED VO2MAX AND REAL-LIFE RUNNING PERFORMANCE

●● ●

R=−0.6

30

40

50

60

70

0.6 0.8 1.0<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

Category●

FastAverageSlow

Gender● Female

Male

a) Best 10km time in relation to VO2max

●● ●

R=−0.56

30

40

50

60

70

1.5 2.0 2.5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

b) Best half marathon time in relation to VO2max

●●

●●

R=−0.61

30

40

50

60

70

3 4 5<− Faster −−− Time (hours) −−− Slower −>

Estim

ated

VO

2max

c) Best marathon time in relation to VO2max

●●

30

40

50

60

70

Fast Average Slow

Estim

ated

VO

2max

d) Runner category and VO2max (all users)

Page 17: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

17!

BHI, 2017! HRV4Training.com!

CONCLUSIONS AND FUTURE WORK

We could provide confirmative insights on the feasibility of!using sub-maximal HR to estimate fitness level in free-living, and use such estimated fitness level as a metric representative of running performance !!Estimated VO2max can potentially be used to track individual performance outside laboratory settings, driving motivation and helping athletes of all levels keep track of progress as well as adopt individualized training plans based on a person’s physiological response to training!!Individual variance should be further investiaged!

Page 18: Talk at the International Conference on Biomedical and Health Informatics (BHI 2017)

Thank you

Marco Altini, PhD !!

[email protected]!@marco_alt!

International Conference on Biomedical and Health Informatics. Orlando, 2017!

HRV4Training.com!