221 Prof. Zekeriya Aktrk 26.02.2011, Sanaa Research Methodology and Practical Biostatistics Using SPSS - Introduction -

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3 Aims and Objectives At teh end of this presentation, the participants should be aware of basic research methodology and be equipped with the information to conduct a research. Objectives –List stages of a research –Ask a clinically answerable question –Classify types of data –Count basic hypothesis tests and their usage –Define types of study designs

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/ 221 Prof. Zekeriya Aktrk , Sanaa Research Methodology and Practical Biostatistics Using SPSS - Introduction - / 222 3 Aims and Objectives At teh end of this presentation, the participants should be aware of basic research methodology and be equipped with the information to conduct a research. Objectives List stages of a research Ask a clinically answerable question Classify types of data Count basic hypothesis tests and their usage Define types of study designs / 224 Let us do a research together Statistics course participants and reasearch Aktrk Z. Sanaa, February 25, 2011 / 225 One literature Askew, DA. et al. GPs involvement in and attitudes to research. Med J Aust 2002;177(2):74-77 / 226 Stages of a research 1.Ask an answerable question 2.Is the question already answered? 3.Formulate hypothesis 4.Decide on the method 5.Application 6.Analysis 7.Interpret results 8.Write report Tyler CW, Epidemyology / 227 Most important: Ideas My research logbook IdeaMethodApplicationReporting 1.Usage of herbal medicine among public 2.Effect of constipation on cognitive functions 3. 1.Medical specialization training in Turkey The effect of structured exercise on weight loss 2.Developing a national EMR database Prevalence of osteoporosis in Edirne 2.Knowledge of herbs by medical students 3.. / 228 Answerable clinical question Patient/problem Intervention Comparison Outcomes Is there a difference between a calorie diet and a glycemic diet in decreasing the body mass index of obese patients? Centre for EBM / 229 Formulating the hypothesis H 0 There is no difference between a calorie diet and a glycemic diet in decreasing the body mass index of obese patients. H 1 There is a significant difference between a calorie diet and a glycemic diet in decreasing the body mass index of obese patients. / 2210 Study designs (How to answer the question?) Observation Case report Prevalence Case control Cohort studies Intervention Randomized controlled studies Methodological Reliability-Validity Sensiivity-Specifity Case-Control Study 11/ 22 Cohort study 12/ 22 RCT 13/ 22 Analysis Data types / 2214 / 2215 Choosing the correct test / 2216 / 2217 Question Is there any significant difference between class 1 and class 6 medical students in recognising thyme? / 2218 Hypothesis H 0 : There is no significant difference between class 1 and class 6 medical students in recognising thyme? H 1 : There is significant difference between class 1 and class 6 medical students in recognising thyme? / 2219 Method Showing the picture of thyme plant to class 1 and class 6 medical students and asking whether they recognize it Analysis - Frequencies / 2220 Analysis Hypothesis test / 2221 / 2222 Interpretation While 12% of class 1 students recognized thyme, this was 78% in class 6 Although class 6 students are better in recognizing thyme, even among them 22% failed. There is a significant difference between class 1 and class 6 medical students in recognizing the picture of thyme (p