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Chapter 6The Effects of Stress on
the Body and Mind
McGraw-Hill/Irwin Copyright © 2012 by The McGraw-Hill Companies, Inc. All rights reserved.
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6-2
From Stress to Disease: The Medical Model
Separates mind and body Used to explain disease and treatment Koch’s Postulates: Every disease has a
single etiologic agent, a microorganism
No recognition of interaction of mind and body
GAS model clearly includes interaction of mind and body
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6-3
Psychosomatic Disease Models
Term coined by Philip Deutsch to illustrate the interaction between the mind and body in the disease process
All illnesses involve mental processes – No separation Common misunderstanding: belief that
psychosomatic diseases are all in one’s head (those are referred to as somatoform disorders)
Selye’s GAS model was a clear break from a medical model approach to disease development
Led to a variety of models on exhaustion and disease development (Schwartz, Everly & Benson, Alexander etc…)
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6-4
Everly & Benson’s Disorders of Arousal Model
(Fig. 6-1 in Text) Potential stressors trigger limbic system
arousal (can become Limbic Hypersensitivity Phenomenon, or LHP)
Limbic arousal triggers neurological, neuronendocrine, and endocrine stress axes
Overstimulation of those axes triggers stress arousal (can become arousal disorder)
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6-5
Two Categories of Psychosomatic Disease
Psychogenic diseaseNo disease-causing pathogenOccurs when chronic stress
response alters structure and function of body
Examples: colitis, atherosclerosis, backache, peptic ulcers
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6-6
Two Forms of Psychosomatic Disease (continued)
Somatogenic diseaseA causative organism existsThe long-term effects of the
stress response weaken the body’s defenses
Example: Mononucleosis, influenza
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6-7
Acute Stress
Alarm-phase stressState of complete mental and
physical readinessPrepared to fight or fleeResult is fatigue
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6-8
Acute Stress Effects on Physical Illness
The body suffers no harm when the lifestyle is balancedProper nutrition and exerciseAdequate rest
The greater the frequency of high level stress, the greater the need for rest
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6-9
Acute Stress Effects on Psychological Illness
Anxiety disordersPanic attacksAcute stress disorderPost-traumatic stress disorder
(PTSD)
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6-10
Chronic Stress
Long-term resistance-phase stress response
General wear and tear on bodyBody parts and systems forced
to work for long periods without adequate rest
Result is malfunction and breakdown
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6-11
Effects of Chronic, Low-Level Stress on Physical
Illness The effects are most clear in
psychogenic diseases Five body systems are most susceptible
Endocrine Muscular Cardiovascular Immune Digestive
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6-12
Chronic Stress and the Endocrine System
The endocrine system perpetuates low-level stress response
Responsible for a wide range of other functions
Chronic stress can interfere with and shut down the endocrine system – i.e. adrenaline, noradrenaline, cortisol.
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6-13
Chronic Stress and the Endocrine System
(continued) Epinephrine production causes
blood vessels to constrict Forces heart to pump under
greater pressure Chronic increase in blood pressure
results in hypertension Hypertension is primary risk factor
for stroke and heart attack
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6-14
Chronic Stress and the Endocrine System
(continued) Norepinephrine production disturbs
platelets and red blood cells Causes damage to endothelium
Precursor to atherosclerosis Converts testosterone into estradiol
Estradiol not completely understoodOften elevated in men who have
heart attacks
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6-15
Chronic Stress and the Endocrine System
(continued)Cortisol production inhibits
breakdown of epinephrine and norepinephrineInterferes with the body’s
ability to relaxIncreases blood cholesterol
and fat levelsThese are recognized risk
factors for heart disease
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6-16
Chronic Stress and the Endocrine System
(continued) Sexual disorders
Men under chronic stressShow reduced levels of testosteroneDemonstrate reduced sexual desireReturn to normal when stress is
removedWomen under chronic stress
Exhibit increased premenstrual syndrome (PMS) symptoms
Research about causes and treatment lack consistency
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6-17
Chronic Stress and the Muscular System
Stress affects all three types of muscle tissueSkeletal musclesSmooth (internal organ) musclesCardiac (heart) muscle
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6-18
Chronic Stress and the Muscular System
(continued) Stress causes a chronic state of
muscle contraction called bracing Skeletal muscles bracing results
HeadacheBackache and muscle painTemporomandibular-joint (TMJ)
syndrome
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6-19
Chronic Stress and the Muscular System
(continued)Smooth muscles bracing results
A chronic state of internal tensionStomach ache and diarrheaHypertension
Cardiac muscle bracing resultsAngina-like symptoms (chest
pains)
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6-20
Chronic Stress and the Cardiovascular System
(continued) The cardiovascular system is a
closed system with three componentsHeartBlood vesselsBlood
Main purpose is to provide food and oxygen to cells and to remove waste
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6-21
Chronic Stress and the Cardiovascular System
(continued)Stress
Accelerates the heart rateMakes the heart pump faster and
under greater pressure than necessary
Increases cholesterol and fats in blood
Causes atherosclerosis in blood vessels
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6-22
Chronic Stress and the Immune System -
Psychoneuroimmunology The immune system performs five
primary functions Identifies foreign substances such as
germs Attacks these invaders Prevents reinfection from these
invaders Destroys mutant cells Resists recurrent chronic infections
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6-23
Chronic Stress and the Immune System (continued)
Chronic stress can alter the immune systemDepletes nutritional factors
associated with immunityCauses an imbalance in the
systemWeakens T cellsExerts a general
immunosuppressive effect
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6-24
Chronic Stress and the Digestive System
Stress upsets the digestive processSmooth muscle tensionExcessive stomach acidsSpasms of esophagus and colonUlcersIncomplete digestion
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6-25
Effects of Chronic Stress on Psychological Illness
Stress is related to many psychological factors Burnout Anxiety disorders Stress-related specific phobia Stress-related generalized anxiety disorder Mood disorders Stress-related major depressive disorder, dysthymic disorder, and
bipolar disorders (and seasonal pattern specifier condition)
Suicide: a permanent solution to a temporary problem People who take their own lives don’t see options (unpredictable
and uncontrollable). Suicide rates for adolescents and college-age people are rising Three stress-related suicide risk factors
Depression Major loss Stressful life events