O N e VISION - Chicago Medicine...Residency North Shore-Long Island Jewish Health System Fellowship Pediatric Ophthalmology and Adult Strabismus, UIC Jason McAnany, PhD Assistant Professor

Illinois Eye and Ear InfirmaryDepartment of Ophthalmology & Visual Sciences

University of Illinois College of Medicine

UPDATE 2011

VISIONO N e

UIC

IN thIS ISSue

New Faculty 2

Faculty 4

Publications 6

Dr. Alexander Retirement 11

NEI K12 Grant 12

Residents and Fellows 14

Sponsored Research 16

Tissue Donor Feature 18

Clinical Investigations/Trials 20

Giving 22

Renovations & Innovations 26

International Doctors 28

t is my pleasure to update you on the developments in the Department of Ophthalmology and Visual Sciences in 2011, which continues to grow and succeed in every area of our mission.

Five years ago I established a clinician-scientist readiness program in the Department. This program provided protected research time and research support to faculty desiring a clinician-scientist career. The program was instrumental for three of our faculty in obtaining clinician-scientist awards from the National Institutes of Health (individual K awards). I am extremely

pleased to announce that the Department received a five-year K12 award from the National Eye Institute last September to support the “UIC K12 Independent Clinical Scientist Development Program” and that three MD, PhD clinician scientists have joined this program! We are one of six Ophthalmology Departments in the nation to be actively supported by the K12 award. As a result of these efforts, the number of NIH-funded clinician-scientists in the Department has now grown from two to a total of nine over the past five years. These clinician-scientists are part of a group of 18 highly talented young faculty recruited during the past 5 years primarily at the assistant professor level. This group represents the future leadership of the Department, contributing to its continued growth into a world class ophthalmological institute.

Over the past five years, the clinical facilities have seen continual growth and renovations. We have expanded and renovated the Retina, Cornea, Contact Lens, Glaucoma, General Eye, Oculoplastic Surgery, and Neuro-Ophthalmology Services. This year, the Pediatric Ophthalmology and Adult Strabismus Service is being renovated. We have also established a Low Vision Service and a Comprehensive Ophthalmology Faculty Practice. The Millennium Park Eye Center, established in 2007, now provides clinical care in all ophthalmic specialties.

The educational mission of the department remains very strong. We established the Illinois Eye Review program in 2008 to coincide with the 150th celebrations of the Illinois Eye and Ear Infirmary. This week-long review program is now in its fifth year and draws approximately 300 national and international participants every year. Additionally, the department has established a new exchange program with Brazil, which is modeled on our highly successful resident exchange program with Keio University in Japan.

Despite the challenges of limits on federal funding to the National Institutes of Health, our basic science research program remains very strong especially with the recruitment of Drs. Dingcai Cao and Jason McAnany, both Principal Investigators for National Eye Institute grants. The departmental core grant, of which I serve as the PI, was renewed through 2014. The Department also received a grant this year to provide a state-of-the art animal facility dedicated to ophthalmology. Research to Prevent Blindness led the way in supporting our corneal, glaucoma and retinal research efforts. These grants, as well as other philanthropic support, have been critical in equipping the core research facilities with advanced cell and molecular biology technology, such as live-cell confocal microscopes.

In closing, I have tremendously enjoyed my tenure as Department Head and I am privileged to have contributed to the successes that the Department has achieved in recent years. Thanks to the generous support of our alumni and donors and the tireless effort of our faculty, residents, fellows and staff, the Department has strengthened its position as a leading ophthalmological institution. As I transition to the Dean’s office, we will continue to be guided by our institutional mission of academic excellence in education, translational research, serving the underserved and treating the most complex medical conditions.

Dimitri T. Azar, MD, MBAInterim Dean, College of MedicineB.A. Field Endowed Chair of Ophthalmologic ResearchProfessor and Department Head, Ophthalmology and Visual Sciences

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Department of Ophthalmology & Visual Sciences | Treating the most serious and complicated ophthalmology cases for over 150 years

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Ahmad Aref, MDAssistant Professor of Ophthalmology GLAuCOMA SERvICE

Dr. Aref is an Assistant Professor of Ophthalmology and an attending physician in the Glaucoma Service. His practice concentrates on minimally invasive glaucoma surgery for patients with mild to moderate glaucomatous disease, particularly those who are experiencing difficulties associated with a medical regimen and the management of glaucomas related to prior vitreoretinal surgical interventions. Dr. Aref joined the faculty in August 2011.

Undergraduate BS, University of Michigan

Medical School MD, Northwestern University Feinberg School of Medicine

Residency Penn State Hershey Eye Center

Fellowship Glaucoma, Bascom Palmer Eye Institute of the University of Miami School of Medicine

Dingcai Cao, PhDAssociate Professor of Ophthalmology DIRECTOR, vISuAL PERCEPTION LABORATORy

Dr. Cao joined the Ophthalmology faculty in September 2011 as a member of the research faculty. He is the principal investigator of a National Eye Institute research grant, Rod-cone Interactions in Mesopic vision (R01Ey1019651). Dr. Cao joins uIC from the University of Chicago, where he earned a PhD in Biopsychology and served on U of C’s ophthalmology faculty. Dr. Cao’s research focuses on finding what the neural mechanisms are that mediate visual processing, and how retinal diseases affect visual functions.

Undergraduate BS, Psychology, Beijing University

Graduate School MS, Biopsychology, Beijing University

MS, Statistics, University of Chicago

Doctorate PhD, Biopsychology, University of Chicago

Fellowship Postdoctoral Fellow, Department of Ophthalmology and Visual Sciences, University of Chicago, Laboratory of Dr. Joel Pokorny

ophthalmology attracts New taleNt

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Iris Kassem, MD, PhDAssistant Professor of Ophthalmology PEDIATRIC OPHTHALMOLOGy AND ADuLT STRABISMuS SERvICE

Dr. Kassem is an Assistant Professor of Ophthalmology and an attending physician in the Pediatric Ophthalmology and Adult Strabismus Service. She specializes in amblyopia, pediatric cataracts and pediatric ocular trauma. Dr. Kassem completed her year-long Pediatric Ophthalmology and Adult Strabismus fellowship at UIC in July, before joining the faculty in September 2011.

Undergraduate BS, Cornell University

Medical School MD, SuNy Health Science Center at Stony Brook

Residency North Shore-Long Island Jewish Health System

Fellowship Pediatric Ophthalmology and Adult Strabismus, UIC

Jason McAnany, PhDAssistant Professor of Ophthalmology DIRECTOR, CLINICAL PSyCHOPHySICS AND ELECTROPHySIOLOGy LABORATORy

Dr. McAnany joined the Department of Ophthalmology in September 2011 as a member of the research faculty. He is the principal investigator of a National Eye Institute research grant, Mechanisms Limiting Visual Performance in Retinal Degenerations (R00Ey019510). His research is focused on defining the relationship between visual dysfunction and the underlying disease processes using psychophysical, electrophysiological, and other noninvasive test procedures, with the goal of developing novel methods for diagnosing and monitoring the progression of visual dysfunction.

Undergraduate BA, Psychology/Biology, Eastern Michigan University

Graduate School MA, Psychology/Behavioral Neuroscience, UIC

Doctorate PhD, Psychology/Behavioral Neuroscience, UIC

Fellowship Department of Ophthalmology and Visual Sciences, UIC Laboratory of Dr. Kenneth Alexander


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Chairs and Vice Chairs

Dimitri Azar, MD, MBA1

Interim Dean, college of medicineBa Field endowed chair of ophthalmologic researchprofessor and Department head of ophthalmology and Visual sciences

Joel Sugar, MD2

professor of ophthalmologyVice chair for clinical operationscornea service

William Mieler, MD3

professor of ophthalmologyVice chair for educationDirector, ocular oncology clinic, retina service

Mahnaz Shahidi, PhD4

morton F. goldberg mD professor of ophthalmologyVice chair for researchDirector, applied physics laboratory

Professors

Kenneth Alexander, PhD5

professor emeritus

Norman Blair, MD6

professor of ophthalmologyDirector, retinal circulation and metabolism laboratory

Debra Goldstein, MD7

professor of ophthalmologyDirector, Uveitis service

Anthony Adamis, MDadjunct professor

Gerald Fishman, MD8

professor emeritus

Nalin Kumar, DPhil9professor of ophthalmology

Jennifer Lim, MD10

marion schenk esq., chair of ophthalmologyDirector, retina service

Irene Maumenee, MD11

research professor of ophthalmologyDirector, ocular genetics laboratory

Timothy McMahon, OD12

professor of ophthalmology

Marilyn Miller, MD13


David Pepperberg, PhD14

searls-schenk professor of ophthalmologyDirector, photoreceptor research laboratory

Allen Putterman, MD15

professor of ophthalmologyco-Director, oculoplastic surgery service

Harris Ripps, PhD, DSc16

professor emeritus

Janet Szlyk, PhDadjunct professor

Howard Tessler, MD17

professor emeritus

Jacob Wilensky, MD18


Beatrice yue, PhD19

thanis a. Field professor of ophthalmologyDirector, ocular cell Biology laboratory

Associate Professors

Nathalie Azar, MD20

associate professor of clinical ophthalmologyDirector, pediatric ophthalmology and adult strabismus

Dingcai Cao, PhD21

associate professor of ophthalmology

Ali Djalilian, MD22

associate professor of ophthalmologyDirector, stem cell research laboratoryDirector of medical student education in ophthalmology

James Goodwin, MD23

associate professor of ophthalmologyDirector, Neuro-ophthalmology service

Charlotte Joslin, OD, PhD24

associate professor of ophthalmologyDirector, contact lens service

Paul Knepper, MD, PhD25

research scientist

Michael Shapiro, MD26

clinical associate professor

Deepak Shukla, PhD27

marion schenk esq., professor of ophthalmologyassociate professor of microbiology and ImmunologyDirector, ocular Virology laboratory

Joan Stelmack, OD28

clinical associate professor of ophthalmologyDirector, low Vision service

Benjamin Ticho, MD29

clinical associate professor

Elmer Tu, MD30

associate professor of clinical ophthalmologyDirector, cornea service

Marlos Viana, PhD31

associate professor of Biostatistics in ophthalmologyassociate professor, college of pharmacy

Assistant Professors

Amjad Ahmad, MD32

clinical assistant professor of ophthalmology

Ahmad Aref, MD33

assistant professor of ophthalmology

Victoria Butcko, OD34 clinical assistant professor of ophthalmology

Jin-Hong Chang, PhD35

research assistant professor of ophthalmologyDirector, angiogenesis research laboratory

Qing Chang, MD, PhD36

research assistant professor of ophthalmology

Felix Chau, MD37

assistant professor of ophthalmologyDirector, retinal Bioengineering laboratory

Soledad Cortina, MD38

assistant professor of ophthalmologyDirector, comprehensive eye service and general eye service

Kimberlee Curnyn, MD39

clinical assistant professor

Jose de la Cruz, MD40

assistant professor of ophthalmologyDirector, millennium park eye center

Anthony Finder, MD41


Robert Fitzgerald, MD42


Molly Gilbert, MD43

clinical assistant professor of ophthalmologyDirector, resident education, James a. lovell Federal health care center

Michael Grassi, MD44

research assistant professor of ophthalmologyDirector, retinal chemical genomics laboratory

Anil Gulati, MD45

clinical assistant professor

Kyuyeon Han, PhD46


David Hillman, MD47


Sandeep Jain, MD48

assistant professor of ophthalmologyDirector, corneal Neurobiology laboratory

Iris Kassem, MD, PhD49


Alexander Khammar, MD50


Charles Kinnaird, OD51


yannek Leiderman, MD, PhD52

assistant professor of ophthalmologyDirector, retinal Bank laboratory

Amy Lin, MD53

assistant professor of pathologyassistant professor of ophthalmologyDirector, ophthalmic pathology laboratory

Mark Lunde, MD54

clinical assistant professor of ophthalmologyDirector of resident education, Jesse Brown Veterans administration

Jason McAnany, PhD55


Heather Moss, MD, PhD56

assistant professor of ophthalmologyDirector, Neuro-ophthalmology research program

Nasser Qtaishat, PhD57

research assistant professor

Pete Setabutr, MD58

assistant professor of ophthalmologyDirector, oculoplastic surgery service

Ellen Shorter, OD59

assistant professor of ophthalmologyDirector, prose clinic

Aisha Traish, MD60

assistant professor of ophthalmologyassociate Director, residency programDirector, pediatric cornea clinic

Larry Ulanski, MD61


Thasarat Vajaranant, MD62

assistant professor of ophthalmologyDirector, glaucoma service

Minhua Wang, MD, PhD63


FacUlty

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9

43 4442 45 484746

49 5351 52 5450 5655

57 58 59 60 61 62 63

15141310 1211 16

17 18 2019 2221 23 24

25

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37 38 40393534 3633

2726 31 3229 3028


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Journal Articles 07/01/10 – 06/30/11

Aakalu VK, Putterman AM. Fat Repositioning in Lower Lid Blepharoplasty: The Role of Titrated Excision. Ophthal Plast Reconstr Surg. 2011 Mar 16. [Epub ahead of print] PubMed PMID: 21415802.

Aakalu VK, Sajja K, Cook JL, Ahmad AZ. Reply re: “Hy-perbaric Oxygen Therapy as Further Adjunctive Therapy in Group A Streptococcus Periorbital Necrotizing Fasciitis”. Ophthal Plast Reconstr Surg. 2010 Aug 30. [Epub ahead of print] PubMed PMID: 20811302.

Afshar AR, Oh FS, Birnbaum AD, Namavari A, Riddle JM, Djalilian AR. Assessing ophthalmoscopy skills. Ophthal-mology. 2010 Sep;117(9):1863,1863.e1-2. PubMed PMID: 20816257.

Amirjamshidi H, Milani By, Sagha HM, Movahedan A, Shafiq MA, Lavker RM, Yue BY, Djalilian AR. Limbal fibroblast conditioned media: a non-invasive treatment for limbal stem cell deficiency. Mol vis. 2011 Mar 8;17:658-66. PubMed PMID: 21403854; PubMed Central PMCID: PMC3056128.

Anastasakis A, McAnany JJ, Fishman GA, Seiple WH. Clinical value, normative retinal sensitivity values, and intra-session repeatability using a combined spectral domain opti-cal coherence tomography/scanning laser ophthalmoscope microperimeter. Eye (Lond). 2011 Feb;25(2):245-51. Epub 2010 Oct 29. PubMed PMID: 21178993; PubMed Central PMCID: PMC3052979.

Anastasakis A, Fishman GA, Lindeman M, Genead MA, Zhou W. Infrared scanning laser ophthalmoscope imaging of the macula and its correlation with functional loss and structural changes in patients with stargardt disease. Retina. 2011 May;31(5):949-58. PubMed PMID: 21293320; PubMed Central PMCID: PMC3116073.

Anastasakis A, Thobani A, Fishman GA, McAnany JJ. Educational levels in patients with stargardt disease. Am J Ophthalmol. 2010 Nov;150(5):737-740.e2. Epub 2010 Aug 5. PubMed PMID: 20688312.

Aref AA, Bennett T, Strong J, Kunselman AR, Scott Iu. Ef-fect of ophthalmic examination procedures on the quality of spectral domain OCT images. Ophthalmic Surg Lasers Imaging. 2011 Feb 1;42 Online:e1-3. doi: 10.3928/15428877-20110125-06. PubMed PMID: 21323259.

Aref AA, Budenz DL. Spectral domain optical coherence tomography in the diagnosis and management of glau-coma. Ophthalmic Surg Lasers Imaging. 2010 Nov-Dec;41 Suppl:S15-27. doi: 10.3928/15428877-20101031-01. Review. PubMed PMID: 21117597.

Aref AA, Scott IU. Management of macular edema second-ary to central retinal vein occlusion: an evidence-based. Adv Ther. 2011 Jan;28(1):40-50. Epub 2010 Dec 9. Review. PubMed PMID: 21153510.

Aref AA, Scott IU. Management of macular edema second-ary to branch retinal vein occlusion: an evidence-based update. Adv Ther. 2011 Jan;28(1):28-39. Epub 2010 Dec 9. Review. PubMed PMID: 21153509.

Bacsa S, Karasneh G, Dosa S, Liu J, Valyi-Nagy T, Shukla D. Syndecan-1 and syndecan-2 play key roles in herpes simplex

virus type-1 infection. J Gen virol. 2011 Apr;92(Pt 4):733-43. Epub 2010 Dec 9. PubMed PMID: 21148276; PubMed Cen-tral PMCID: PMC3133699.

Baker S, Booth C, Fillman C, Shapiro M, Blair MP, Hyland JC, Ala-Kokko L. A loss of function mutation in the COL9A2 gene causes autosomal recessive Stickler syndrome. Am J Med Genet A. 2011 Jul;155A(7):1668-72. doi: 10.1002/ajmg.a.34071. Epub 2011 Jun 10. PubMed PMID: 21671392.

Belforte N, Sande P, de Zavalía N, Knepper PA, Rosenstein RE. Effect of chondroitin sulfate on intraocular pressure in rats. Invest Ophthalmol vis Sci. 2010 Nov;51(11):5768-75. Epub 2010 Jun 23. PubMed PMID: 20574017.

Beyer J, Zhao XC, yee R, Khaliq S, McMahon TT, ying H, Yue BY, Malicki JJ. The role of crumbs genes in the vertebrate cornea. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4549-56. PubMed PMID: 20805571; PubMed Cen-tral PMCID: PMC2941173.

Birnbaum AD, Jiang y, Tessler HH, Goldstein DA. El-evation of intraocular pressure in patients with uveitis treated with topical difluprednate. Arch Ophthalmol. 2011 May;129(5):667-8. Erratum in: Arch Ophthalmol. 2011 Jul;129(7):935. PubMed PMID: 21555625.

Birnbaum AD, Little DM, Tessler HH, Goldstein DA. Etiol-ogies of chronic anterior uveitis at a tertiary referral center over 35 years. Ocul Immunol Inflamm. 2011 Feb;19(1):19-25. Epub 2010 Nov 6. PubMed PMID: 21054197.

Birnbaum AD, Oh FS, Chakrabarti A, Tessler HH, Gold-stein DA. Clinical features and diagnostic evaluation of biopsy-proven ocular sarcoidosis. Arch Ophthalmol. 2011 Apr;129(4):409-13. PubMed PMID: 21482866.

Birnbaum AD, Oh F, Sahin O, Little DM, Tessler HH, Gold-stein DA. Chlorambucil and malignancy. Ophthalmology. 2010 Jul;117(7):1466-1466.e1. PubMed PMID: 20610006.

Birnbaum AD, Tessler HH, Goldstein DA. Sympathetic ophthalmia in Operation Iraqi Freedom. Am J Ophthalmol. 2010 Nov;150(5):758-9. PubMed PMID: 21036221.

Cao D, Pokorny J, Grassi MA. Isolated mesopic rod and cone electroretinograms realized with a four-primary meth-od. Doc Ophthalmol. 2011 Aug;123(1):29-41. doi: 10.1007/s10633-011-9279-9. Epub 2011 Jun 24. PubMed PMID: 21701875; PubMed Central PMCID: PMC3150787.

Chang JR, Koo E, Agrón E, Hallak J, Clemons T, Azar D, Sperduto RD, Ferris FL 3rd, Chew Ey; Age-Related Eye Disease Study Group. Risk Factors Associated with Incident Cataracts and Cataract Surgery in the Age-Related Eye Dis-ease Study (AREDS) AREDS Report Number 32. Ophthal-mology. 2011 Jun 17. [Epub ahead of print] PubMed PMID: 21684602; PubMed Central PMCID: PMC3178670.

Choi DE, Birnbaum AD, Oh F, Tessler HH, Goldstein DA. Pediatric uveitis secondary to probable, presumed, and biopsy-proven sarcoidosis. J Pediatr Ophthalmol Strabismus. 2011 May 1;48(3):157-62. doi: 10.3928/01913913-20100518-01. Epub 2010 May 21. PubMed PMID: 20506967.

Chow CC, Kiernan DF, Chau FY, Blair MP, Ticho BH, Galasso JM, Shapiro MJ. Laser photocoagulation at birth prevents blindness in Norrie’s disease diagnosed using amniocentesis. Ophthalmology. 2010 Dec;117(12):2402-6. PubMed PMID: 20619898.

Cole EA, Winn BJ, Putterman AM. Measurement of eyebrow position from inferior corneal limbus to brow: a new technique. Ophthal Plast Reconstr Surg. 2010 Nov-Dec;26(6):443-7. PubMed PMID: 20724865.

Cortina MS, Bazan HE. Docosahexaenoic acid, protec-tins and dry eye. Curr Opin Clin Nutr Metab Care. 2011 Mar;14(2):132-7. Review. PubMed PMID: 21157308.

Davis LT, Kumar N, Nijm LM, Ulanski LJ 2nd, Tu EY, Fis-cella RG, Peterson RJ, Glickman RD. An adaptable HPLC method for the analysis of frequently used antibiotics in ocular samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 15;878(26):2421-6. Epub 2010 Aug 8. PubMed PMID: 20739230.

Dhingra A, Fina ME, Neinstein A, Ramsey DJ, Xu y, Fish-man GA, Alexander KR, Qian H, Peachey NS, Gregg RG, Vardi N. Autoantibodies in melanoma-associated retinopathy target TRPM1 cation channels of retinal ON bipolar cells. J Neurosci. 2011 Mar 16;31(11):3962-7. PubMed PMID: 21411639; PubMed Central PMCID: PMC3073846.

Dosa S, Castellanos K, Bacsa S, Gagyi E, Kovacs SK, valyi-Nagy K, Shukla D, Dermody TS, Valyi-Nagy T. Chronic progressive deficits in neuron size, density and number in the trigeminal ganglia of mice latently infected with herpes simplex virus. Brain Pathol. 2011 Sep;21(5):583-93. doi: 10.1111/j.1750-3639.2011.00485.x. Epub 2011 Apr 3. PubMed PMID: 21371157; PubMed Central PMCID: PMC3125479.

Drapala PW, Brey EM, Mieler WF, Venerus DC, Kang Der-went JJ, Perez-Luna VH., Role of thermo-responsiveness and poly(ethylene glycol) diacrylate cross-link density on protein release from poly (N-isopropylacrylamide) hydrogels. J Bio-mater Sci Polym Ed, 22 (2011), pp. 59–75.

Edward DP, Patil AJ, Sugar J, Parikh M. Copper deposition in a variant of multiple myeloma: pathologic changes in the cornea and the lens capsule. Cornea. 2011 Mar;30(3):360-3. PubMed PMID: 21045663.

Elderkin S, Tu E, Sugar J, Reddy S, Kadakia A, Ramaswamy R, Djalilian A. Outcome of descemet stripping automated endothelial keratoplasty in patients with an anterior cham-ber intraocular lens. Cornea. 2010 Nov;29(11):1273-7. PubMed PMID: 20697283.

Emerson Mv, Saffra N, Louis LS, Lin AY, Folberg R, Abramson DH. Anterior Segment Retinoblastoma Detect-able on Magnetic Resonance Imaging. Retinal Cases and Brief Reports, Summer 2010,4(3):243-245.

Emoto H, Emoto y, Lim, JI, Sadun AA, Sebag J. Regression of Choroidal Neovascularization After Vitrectomy for Postin-jection Endophthalmitis. Retinal Cases and Brief Reports, Fall 2010,4(4):312-316.

Estrada-Cuzcano A, Koenekoop RK, Coppieters F, Kohl S, Lopez I, Collin RW, De Baere EB, Roeleveld D, Marek J, Bernd A, Rohrschneider K, van den Born LI, Meire F, Mau-menee IH, Jacobson SG, Hoyng CB, Zrenner E, Cremers FP, den Hollander AI. IQCB1 mutations in patients with leber congenital amaurosis. Invest Ophthalmol Vis Sci. 2011 Feb 11;52(2):834-9. Print 2011 Feb. PubMed PMID: 20881296.

UIC Ophthalmology and Visual Sciences

FacUlty pUBlIcatIoNs 2010-11

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Farooq AV, Shukla D. Corneal latency and transmission of herpes simplex virus-1. Future virol. 2011 Jan;6(1):101-108. PubMed PMID: 21436960; PubMed Central PMCID: PMC3061464.

Fishman GA. Historical evolution in the understanding of Stargardt macular dystrophy. Ophthalmic Genet. 2010 Dec;31(4):183-9. Epub 2010 Sep 1. PubMed PMID: 20809774.

Friberg TR, Tolentino M; LEvEL Study Group (Mieler EF), Weber P, Patel S, Campbell S, Goldbaum M. Pegaptanib sodium as maintenance therapy in neovascular age-related macular degeneration: the LEvEL study. Br J Ophthalmol. 2010 Dec;94(12):1611-7. Epub 2010 May 14. PubMed PMID: 20472746; PubMed Central PMCID: PMC2991041.

Garcia JP Jr, Ritterband DC, Buxton DF, de la Cruz J. Evalu-ation of the stability of Boston type I keratoprosthesis-do-nor cornea interface using anterior segment optical coher-ence tomography. Cornea. 2010 Sep;29(9):1031-5. PubMed PMID: 20517152.

Gatinel D, Malet J, Hoang-Xuan T, Azar DT. Corneal elevation topography: best fit sphere, elevation distance, asphericity, toricity, and clinical implications. Cornea. 2011 May;30(5):508-15. PubMed PMID: 21107250.

Genead MA, Fishman GA. Cystic macular oedema on spectral-domain optical coherence tomography in cho-roideremia patients without cystic changes on fundus examination. Eye (Lond). 2011 Jan;25(1):84-90. Epub 2010 Oct 22. PubMed PMID: 20966974; PubMed Central PMCID: PMC3020991.

Genead MA, Fishman GA, Anastasakis A, Lindeman M. Macular vitelliform lesion in desferrioxamine-related reti-nopathy. Doc Ophthalmol. 2010 Oct;121(2):161-6. Epub 2010 Jun 9. PubMed PMID: 20532952.

Genead MA, Fishman GA, Anastasakis A. Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with Stargardt disease. Br J Oph-thalmol. 2011 May;95(5):689-93. Epub 2010 Oct 8. PubMed PMID: 20935302.

Genead MA, Fishman GA, Lindeman M. Structural and functional characteristics in carriers of X-linked retinitis pigmentosa with a tapetal-like reflex. Retina. 2010 Nov-Dec;30(10):1726-33. PubMed PMID: 20829740; PubMed Central PMCID: PMC2978770.

Genead MA, Fishman GA, McAnany JJ. Efficacy of topi-cal dorzolamide for treatment of cystic macular lesions in a patient with enhanced S-cone syndrome. Doc Ophthalmol. 2010 Dec;121(3):231-40. Epub 2010 Sep 15. PubMed PMID: 20842519.

Genead MA, McAnany JJ, Fishman GA. Retinal nerve fi-ber thickness measurements in choroideremia patients with spectral-domain optical coherence tomography. Ophthalmic Genet. 2011 Jun;32(2):101-6. Epub 2011 Jan 26. PubMed PMID: 21268676.

Gowrisankaran S, Anastasakis A, Fishman GA, Alexander KR. Structural and functional measures of inner retinal integrity following visual acuity improvement in a patient with hereditary motor and sensory neuropathy type VI. Ophthalmic Genet. 2011 Sep;32(3):188-92. Epub 2011 Jun 27. PubMed PMID: 21707411; PubMed Central PMCID: PMC3155637.

Graeber CP, Gobin yP, Marr BP, Dunkel IJ, Brodie SE, Born-feld N, Char DH, Folberg R, Imhof SM, Lin AY, Berry JL, Al Mesfer S, Moll AC, Abramson DH. Histopathologic findings of eyes enucleated after treatment with chemo-surgery for retinoblastoma. Open Ophthalmol J. 2011 Jan 18;5:1-5. PubMed PMID: 21399766; PubMed Central PMCID: PMC3052645.

Grassi MA, Tikhomirov A, Ramalingam S, Below JE, Cox NJ, Nicolae DL. Genome-wide meta-analysis for severe diabetic retinopathy. Hum Mol Genet. 2011 Jun 15;20(12):2472-81. Epub 2011 Mar 26. PubMed PMID: 21441570; PubMed Cen-tral PMCID: PMC3098732.

Gupta S, Aakalu VK, Ahmad AZ. Late-onset orbital hema-toma secondary to alloplastic orbital implant mimicking transient ischemic attacks. Ophthal Plast Reconstr Surg. 2011 Jan-Feb;27(1):e18-20. PubMed PMID: 20700069.

Gupta S, Aakalu VK, Sajja K, Rosso RO, Ahmad AZ. Peri-orbital physical urticaria in an anophthalmic patient with dermatographism. Ophthal Plast Reconstr Surg. 2011 Jan-Feb;27(1):e20-1. PubMed PMID: 21217333.

Gupta S, Blair MP, Lin AY, David O, Tessler HH, Gold-stein DA. Cutaneous Melanoma Metastatic To the Vitreous Cavity. Retinal Cases and Brief Reports, Retinal Cases and Brief Reports, Summer 2011,5(3):197-200.

Gussin HA, Khasawneh FT, Xie A, Feng F, Memic A, Qian H, Le Breton GC, Pepperberg DR. Subunit-specific polyclonal antibody targeting human ρ1 GABA(C) receptor. Exp Eye Res. 2011 Jul;93(1):59-64. Epub 2011 Apr 23. PubMed PMID: 21536029; PubMed Central PMCID: PMC3138833.

Gussin HA, Tomlinson ID, Muni NJ, Little DM, Qian H, Rosenthal SJ, Pepperberg DR. GABAC receptor binding of quantum-dot conjugates of variable ligand valency. Bioconjug Chem. 2010 Aug 18;21(8):1455-64. PubMed PMID: 20715850; PubMed Central PMCID: PMC2929923.

Henry JJ, Tsonis PA. Molecular and cellular aspects of amphibian lens regeneration. Prog Retin Eye Res. 2010 Nov;29(6):543-55. Epub 2010 Jul 16. PubMed PMID: 20638484.

Hoang QV, Chau FY, Blair MP. Shapiro MJ. Optical Co-herence Tomography of Nasal Sliding of the Retina and Tem-poral Arcades in Retinopathy of Prematurity. Retinal Cases and Brief Reports. Spring 2011,5(2):165-166.

Hoang QV, Chau FY, Shahidi M, Lim JI. Central macular splaying and outer retinal thinning in asymptomatic sickle cell patients by spectral-domain optical coherence tomog-raphy. Am J Ophthalmol. 2011 Jun;151(6):990-994.e1. Epub 2011 Mar 31. PubMed PMID: 21457923.

Hoang QV, Blair MP, Rahmani B, Galasso JM, Shapiro MJ. Multiple retinal holes and peripheral nonperfusion in muscle-eye-brain disease. Arch Ophthalmol. 2011 Mar;129(3):373-5. PubMed PMID: 21403000.

Hoang QV, Chau FY, Shahidi M, Miller MT, Blair MP. Macular thinning associated with unilateral optic nerve hypoplasia. Ophthalmic Surg Lasers Imaging. 2011 Feb 1;42 Online:e6-9. doi: 10.3928/15428877-20110125-08. PubMed PMID: 21323261.

Hoang QV, Kiernan DF, Chau FY, Shapiro MJ, Blair MP. Fluorescein angiography of recurrent retinopathy of pre-maturity after initial intravitreous bevacizumab treatment. Arch Ophthalmol. 2010 Aug;128(8):1080-1. PubMed PMID: 20697016.

Hoang QV, Qian H, Ripps H. Functional analysis of hemi-channels and gap-junctional channels formed by connexins 43 and 46. Mol vis. 2010 Jul 15;16:1343-52. PubMed PMID: 20664797; PubMed Central PMCID: PMC2905638.

Jabs DA, Ahuja A, Van Natta M, Lyon A, Srivastava S, Ganga-putra S; Studies of the Ocular Complications of AIDS Re-search Group (Lim JI). Course of cytomegalovirus retinitis in the era of highly active antiretroviral therapy: five-year outcomes. Ophthalmology. 2010 Nov;117(11):2152-61.e1-2. Epub 2010 Jul 29. PubMed PMID: 20673591; PubMed Central PMCID: PMC2963687.

Jayaprakash PA, Edward DP, Wong M, Ravichandran P, Gold-stein DA. The role of perivascular melanophage infiltrates in the conjunctiva in sympathetic ophthalmia. Ocul.Immunol.Inflamm. 2011;19:186-191.

Joy A, Mohammed TA, Al-Ghoul KJ. Abnormal fiber end migration in Royal College of Surgeons rats during posterior subcapsular cataract formation. Mol vis. 2010 Jul 31;16:1453-66. PubMed PMID: 20806082; PubMed Central PMCID: PMC2925909.

Karasneh GA, Ali M, Shukla D. An Important Role for Syn-decan-1 in Herpes Simplex Virus Type-1 Induced Cell-to-Cell Fusion and virus Spread. PLoS One. 2011;6(9):e25252. Epub 2011 Sep 21. PubMed PMID: 21957484; PubMed Central PMCID: PMC3177890.

Kiernan DF, Al-Heeti O, Blair MP, Keenan JD, Lichtenstein SJ, Tsilou ET, Smaoui N, Shapiro MJ. Peripheral retinal non-perfusion in septo-optic dysplasia (de Morsier syndrome). Arch Ophthalmol. 2011 May;129(5):671-3. PubMed PMID: 21555628.

Kiernan DF, Blair MP, Shapiro MJ. In utero diagnosis of Norrie disease and early laser preserves visual acuity. Arch Ophthalmol. 2010 Oct;128(10):1382. PubMed PMID: 20938020.

Kiernan DF, Blair MP, Shapiro MJ. Neovasculariza-tion after nonaccidental trauma. Ophthalmology. 2010 Dec;117(12):2443.e1-2. PubMed PMID: 21129574.

Kiernan DF, Hariprasad SM, Rusu IM, Mehta SV, Mieler WF, Jager RD. Epidemiology of the association between anticoagulants and intraocular hemorrhage in patients with neovascular age-related macular degeneration. Retina. 2010 Nov-Dec;30(10):1573-8. PubMed PMID: 21060269.

Kiernan DF, Ksiazek SM, Jampol LM, Grassi MA. Photore-ceptor Attenuation in Acute Zonal Occult Outer Retinopa-thy. Retinal Cases and Brief Reports, Fall 2010,4(4):339-345.

Kiernan DF, Mieler WF, Hariprasad SM. Variety, variability and veracity: macular thickness and reproducibility among optical coherence tomography systems. Am J Ophthalmol. 2010 Aug;150(2):138-140.e2. PubMed PMID: 20670737.

Kiernan DF, Shah RJ, Hariprasad SM, Grassi MA, Small KW, Kiernan JP, Mieler WF. Thirty-year follow-up of an African-American family with macular dystrophy of the retina, locus 1 (North Carolina macular dystrophy). Ophthalmology. 2011 Jul;118(7):1435-43. Epub 2011 Feb 18. PubMed PMID: 21310494.

Kim BM, Shapiro MJ, Miller MT, Blair MP. Peripapillary Staphyloma With Associated Retinopathy of Prematurity. Retinal Cases and Brief Reports, Spring 2011,5(2):146-148.

Krakauer M, Aakalu VK, Davis PL, Ahmad AZ. Silicone Spacer Repair of Medial Rectus After Iatrogenic Orbit Frac-ture. Ophthal Plast Reconstr Surg. 2011 Jun 21. [Epub ahead of print] PubMed PMID: 21697756.

Li Sy, Birnbaum AD, Goldstein DA. Optic neuritis as-sociated with adalimumab in the treatment of uveitis. Ocul Immunol Inflamm. 2010 Dec;18(6):475-81. Epub 2010 Sep 1. Review. PubMed PMID: 20809867.

Lim JI, Fung AE, Wieland M, Hung D, Wong v. Sustained-release intravitreal liquid drug delivery using triamcinolone acetonide for cystoid macular edema in retinal vein occlu-sion. Ophthalmology. 2011 Jul;118(7):1416-22. Epub 2011 Mar 12. PubMed PMID: 21397950.

Bold: Faculty Blue: Fellow Green: Resident


8

Lim JI, Spee C, Hinton DR. A comparison of hypoxia-inducible factor-α in surgically excised neovascular mem-branes of patients with diabetes compared with idiopathic epiretinal membranes in nondiabetic patients. Retina. 2010 Oct;30(9):1472-8. PubMed PMID: 20811317.

Loduca AL, Zhang C, Zelkha R, Shahidi M. Thickness map-ping of retinal layers by spectral-domain optical coherence tomography. Am J Ophthalmol. 2010 Dec;150(6):849-55. Epub 2010 Oct 16. PubMed PMID: 20951975; PubMed Cen-tral PMCID: PMC2991435.

Mahdi N, Faia LJ, Goodwin J, Nussenblatt RB, Nida Sen H. A case of autoimmune retinopathy associated with thyroid carcinoma. Ocul.Immunol.Inflamm. 2010;18:322-323.

Marcet MM, Setabutr P, Lemke BN, Collins ME, Flem-ing JC, Wesley RE, Pinto JM, Putterman AM. Surgical mi-croanatomy of the müller muscle-conjunctival resection ptosis procedure. Ophthal Plast Reconstr Surg. 2010 Sep-Oct;26(5):360-4. PubMed PMID: 20622700.

Marmor MF, Kellner u, Lai Ty, Lyons JS, Mieler WF; Ameri-can Academy of Ophthalmology. Revised recommendations on screening for chloroquine and hydroxychloroquine reti-nopathy. Ophthalmology. 2011 Feb;118(2):415-22. PubMed PMID: 21292109.

McAnany JJ, Shahidi M, Applegate RA, Zelkha R, Alex-ander KR. Contributions of optical and non-optical blur to variation in visual acuity. Optom vis Sci. 2011 Jun;88(6):716-23. PubMed PMID: 21460756; PubMed Central PMCID: PMC3100362.

McAnany JJ, Alexander KR. Spatial contrast sensitivity in dynamic and static additive luminance noise. Vision Res. 2010 Sep 15;50(19):1957-65. Epub 2010 Jul 16. PubMed PMID: 20638404; PubMed Central PMCID: PMC2926298.

Memic A, Volgina VV, Gussin HA, Pepperberg DR, Kay BK. Generation of recombinant guinea pig antibody fragments to the human GABAC receptor. J Immunol Methods. 2011 May 31;368(1-2):36-44. Epub 2011 Feb 26. PubMed PMID: 21362428; PubMed Central PMCID: PMC3100176.

Nassiri N, Pandya HK, Djalilian AR. Limbal allograft transplantation using fibrin glue. Arch Ophthalmol. 2011 Feb;129(2):218-22. PubMed PMID: 21320970.

Nguyen QD, Shah SM, Khwaja AA, Channa R, Hatef E, Do Dv, Boyer D, Heier JS, Abraham P, Thach AB, Lit ES, Foster BS, Kruger E, Dugel P, Chang T, Das A, Ciulla TA, Pollack JS, Lim JI, Eliott D, Campochiaro PA; READ-2 Study Group. Two-year outcomes of the ranibizumab for edema of the macula in diabetes (READ-2) study. Ophthalmology. 2010 Nov;117(11):2146-51. Epub 2010 Sep 19. Erratum in: Oph-thalmology. 2011 Jun;118(6):1016. Eliot, Dean [corrected to Eliott, Dean]. PubMed PMID: 20855114.

Park B, ying H, Shen X, Park JS, Qiu y, Shyam R, Yue BY. Impairment of protein trafficking upon overexpression and mutation of optineurin. PLoS One. 2010 Jul 12;5(7):e11547. PubMed PMID: 20634958; PubMed Central PMCID: PMC2902519.

Patil AJ, Edward DP, Wong M, Ravichandran P, Goldstein DA. The role of perivascular melanophage infiltrates in the con-junctiva in sympathetic ophthalmia. Ocul Immunol Inflamm. 2011 Jun;19(3):186-91. PubMed PMID: 21595534.

Pham M, Chow CC, Badawi D, Tu EY. use of infliximab in the treatment of peripheral ulcerative keratitis in Crohn disease. Am J Ophthalmol. 2011 Aug;152(2):183-188.e2. Epub 2011 Jun 8. PubMed PMID: 21652024.

Pineles SL, Avery RA, Moss HE, Finkel R, Blinman T, Kaiser L, Liu GT. Visual and systemic outcomes in pediatric ocular myasthenia gravis. Am J Ophthalmol. 2010 Oct;150(4):453-459.e3. Epub 2010 Aug 1. PubMed PMID: 20678749.

Puhan MA, Van Natta ML, Palella FJ, Addessi A, Meinert C; Ocular Complications of AIDS Research Group (Lim JI). Excess mortality in patients with AIDS in the era of highly active antiretroviral therapy: temporal changes and risk factors. Clin Infect Dis. 2010 Oct 15;51(8):947-56. PubMed PMID: 20825306; PubMed Central PMCID: PMC2943970.

Pula JH, Towle VL, Staszak VM, Cao D, Bernard JT, Gomez CM. Retinal Nerve Fibre Layer and Macular Thinning in Spinocerebellar Ataxia and Cerebellar Multisystem Atrophy. Neuroophthalmology. 2011 Jun;35(3):108-114. PubMed PMID: 21866205; PubMed Central PMCID: PMC3159168.

Putterman AM. Instilling ocular ointments without blurred vision. Ophthal Plast Reconstr Surg. 2010 Nov-Dec;26(6):503. PubMed PMID: 20811310.

Qian H, Ripps H. Neurovascular interaction and the pathophysiology of diabetic retinopathy. Exp Diabetes Res. 2011;2011:693426. Epub 2011 Feb 21. PubMed PMID: 21747832; PubMed Central PMCID: PMC3124285.

Qian H, Alexander KR, Ripps H. Harmonic analysis of the cone flicker ERG of rabbit. Exp Eye Res. 2010 Dec;91(6):811-7. Epub 2010 Oct 23. PubMed PMID: 20974130; PubMed Central PMCID: PMC2996095.

Roberts DK, Lukic A, yang y, Wilensky JT, Wernick MN. Multispectral Diagnostic Imaging of the Iris in Pigment Dis-persion Syndrome. J Glaucoma. 2011 Mar 16. [Epub ahead of print] PubMed PMID: 21423031; PubMed Central PMCID: PMC3153570.

Rowan MJ, Ripps H, Shen W. Fast glutamate uptake via EAAT2 shapes the cone-mediated light offset response in bipolar cells. J Physiol. 2010 Oct 15;588(Pt 20):3943-56. PubMed PMID: 20807794; PubMed Central PMCID: PMC3000584.

Rush RB, Goldstein DA, Callanan DG, Meghpara B, Feuer WJ, Davis JL. Outcomes of birdshot chorioretinopathy treated with an intravitreal sustained-release fluocino-lone acetonide-containing device. Am J Ophthalmol. 2011 Apr;151(4):630-6. Epub 2011 Feb 1. PubMed PMID: 21277557.

Sapitro J, Dunmire JJ, Scott SE, Sutariya v, Geldenhuys WJ, Hewit M, Yue BY, Nakamura H. Suppression of trans-forming growth factor-β effects in rabbit subconjunctival fibroblasts by activin receptor-like kinase 5 inhibitor. Mol vis. 2010 Sep 16;16:1880-92. PubMed PMID: 21031133; PubMed Central PMCID: PMC2956700.

Saraiya NV, Goldstein DA. Dexamethasone for ocular inflammation. Expert Opin Pharmacother. 2011 May;12(7):1127-31. Epub 2011 Apr 2. PubMed PMID: 21457057.

Sen HN, Sangave AA, Goldstein DA, Suhler EB, Cun-ningham D, Vitale S, Nussenblatt RB. A standardized grading system for scleritis. Ophthalmology. 2011 Apr;118(4):768-71. Epub 2010 Nov 20. PubMed PMID: 21093921; PubMed Cen-tral PMCID: PMC3070789.

Sepahdari AR, Aakalu VK, Setabutr P, Shiehmorteza M, Na-heedy JH, Mafee MF. Indeterminate orbital masses: restricted diffusion at MR imaging with echo-planar diffusion-weighted imaging predicts malignancy. Radiology. 2010 Aug;256(2):554-64. PubMed PMID: 20656840.

Sezgin E, van Natta ML, Ahuja A, Lyon A, Srivastava S, Troyer JL, O’Brien SJ, Jabs DA; Studies of the Ocular Complica-tions of AIDS Research Group (Lim JI). Association of host genetic risk factors with the course of cytomegalovirus reti-nitis in patients infected with human immunodeficiency virus. Am J Ophthalmol. 2011 Jun;151(6):999-1006.e4. Epub 2011 Mar 10. PubMed PMID: 21396623; PubMed Central PMCID: PMC3103625.

Shah A, Farooq AV, Tiwari V, Kim MJ, Shukla D. HSV-1 infec-tion of human corneal epithelial cells: receptor-mediated en-try and trends of re-infection. Mol vis. 2010 Nov 20;16:2476-86. PubMed PMID: 21139972; PubMed Central PMCID: PMC2994737.

Shahidi M, Wanek J, Blair NP, Little DM, Wu T. Retinal tissue oxygen tension imaging in the rat. Invest Ophthalmol vis Sci. 2010 Sep;51(9):4766-70. Epub 2010 Apr 7. PubMed PMID: 20375336; PubMed Central PMCID: PMC2941162.

Shapiro MJ, Chow CC, Karth PA, Kiernan DF, Blair MP. Effects of green diode laser in the treatment of pediatric Coats disease. Am J Ophthalmol. 2011 Apr;151(4):725-731.e2. Epub 2011 Jan 22. PubMed PMID: 21257148.

Shen X, ying H, Qiu y, Park JS, Shyam R, Chi ZL, Iwata T, Yue BY. Processing of optineurin in neuronal cells. J Biol Chem. 2011 Feb 4;286(5):3618-29. Epub 2010 Nov 8. PubMed PMID: 21059646; PubMed Central PMCID: PMC3030366.

Taneri S, Oehler S, Azar DT. Influence of mydriatic eye drops on wavefront sensing with the Zywave aber-rometer. J Refract Surg. 2011 Sep;27(9):678-85. doi: 10.3928/1081597X-20110317-01. Epub 2011 Mar 31. PubMed PMID: 21446641.

Taneri S, Weisberg M, Azar DT. Surface ablation techniques. J Cataract Refract Surg. 2011 Feb;37(2):392-408. Review. PubMed PMID: 21241926.

Thobani A, Anastasakis A, Fishman GA. Microperimetry and OCT findings in female carriers of choroideremia. Ophthalmic Genet. 2010 Dec;31(4):235-9. PubMed PMID: 21067487.

Thobani A, Fishman GA, Genead M, Anastasakis A. Visual acuity loss in recessive retinitis pigmentosa and its correla-tion with macular lesions. Retina. 2011 May;31(5):967-72. PubMed PMID: 21252818.

Thobani A, Fishman GA. The use of carbonic anhydrase inhibitors in the retreatment of cystic macular lesions in retinitis pigmentosa and X-linked retinoschisis. Retina. 2011 Feb;31(2):312-5. PubMed PMID: 20966823.

Tiwari V, Liu J, Valyi-Nagy T, Shukla D. Anti-heparan sulfate peptides that block herpes simplex virus infection in vivo. J Biol Chem. 2011 Jul 15;286(28):25406-15. Epub 2011 May 19. PubMed PMID: 21596749; PubMed Central PMCID: PMC3137111.

Tiwari V, Darmani NA, Yue BY, Shukla D. In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type-1 infection. Phytother Res. 2010 Aug;24(8):1132-40. PubMed PMID: 20041417.

Tiwari V, Shukla D. Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry. J Gen virol. 2010 Dec;91(Pt 12):3002-9. Epub 2010 Sep 1. PubMed PMID: 20810749; PubMed Central PMCID: PMC3052565.

Traish AS, Chodosh J. Expanding application of the Bos-ton type I keratoprosthesis due to advances in design and improved post-operative therapeutic strategies. Semin Ophthalmol. 2010 Sep-Nov;25(5-6):239-43. Review. PubMed PMID: 21091006.

9

Tu EY, Joslin CE, Shoff ME. Successful treatment of chronic stromal acanthamoeba keratitis with oral voriconazole monotherapy. Cornea. 2010 Sep;29(9):1066-8. PubMed PMID: 20539217; PubMed Central PMCID: PMC2926250.

Tu EY, Joslin CE. Recent outbreaks of atypical contact lens-related keratitis: what have we learned? Am J Ophthal-mol. 2010 Nov;150(5):602-608.e2. PubMed PMID: 21036209; PubMed Central PMCID: PMC2991148.

Turturro SB, Guthrie MJ, Appel AA, Drapala PW, Brey EM, Pérez-Luna vH, Mieler WF, Kang-Mieler JJ. The ef-fects of cross-linked thermo-responsive PNIPAAm-based hydrogel injection on retinal function. Biomaterials. 2011 May;32(14):3620-6. Epub 2011 Feb 12. PubMed PMID: 21320724.

Vajaranant TS, Anderson RJ, Zelkha R, Zhang C, Wilen-sky JT, Edward DP, Shahidi M. The relationship between macular cell layer thickness and visual function in different stages of glaucoma. Eye (Lond). 2011 May;25(5):612-8. Epub 2011 Feb 25. PubMed PMID: 21350568; PubMed Central PMCID: PMC3093432.

Vajaranant TS, Blair MP, McMahon T, Wilensky JT, de la Cruz J. Special considerations for pars plana tube-shunt placement in Boston type 1 keratoprosthesis. Arch Ophthal-mol. 2010 Nov;128(11):1480-2. PubMed PMID: 21060051.

Vasaiwala R, Sajja K, Setabutr P. Novel Management of the Microphthalmic Orbit in a Patient With PHACE Syndrome. Ophthal Plast Reconstr Surg. 2011 May 27. [Epub ahead of print] PubMed PMID: 21629142.

Vasconcelos-Santos DV, Lim JI, Rao NA. Chronic coccidioi-domycosis endophthalmitis without concomitant systemic involvement: a clinicopathological case report. Ophthalmol-ogy. 2010 Sep;117(9):1839-42. Epub 2010 May 14. PubMed PMID: 20471688; PubMed Central PMCID: PMC2933969.

velez-Montoya R, Rascón-vargas D, Mieler WF, Fromow-Guerra J, Morales-Cantón v. Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report. J Ophthal-mol. 2010;2010. pii: 169739. Epub 2010 Jul 14. PubMed PMID: 20706679; PubMed Central PMCID: PMC2913728.

Venneti S, Moss HE, Levin MH, vagefi MR, Brozena SC, Pruitt AA, Mourelatos Z, Trojanowski JQ, Galetta SL, Balcer LJ. Asymmetric bilateral demyelinating optic neuropathy from tacrolimus toxicity. J Neurol Sci. 2011 Feb 15;301(1-2):112-5. Epub 2010 Nov 26. PubMed PMID: 21112060.

Weisberg MP, Sugar J. Modalities to decrease stromal her-pes simplex keratitis reactivation rates. Arch Ophthalmol. 2010 Nov;128(11):1497; author reply 1497-8. PubMed PMID: 21060060.

Winokur J, Lee J, Kumar G, Azar DT. Surgical technique of femtosecond dovetail rotational autograft. Br J Ophthalmol. 2011 Mar;95(3):434-6. Epub 2010 Dec 13. PubMed PMID: 21156703.

yeh SI, Han Ky, Sabri A, Rosenblatt MI, Azar DT, Jain S, Chang JH. MMP-7 knock-in corneal fibroblast cell lines secrete MMP-7 with proteolytic activity towards collagen XvIII. Curr Eye Res. 2010 Sep;35(9):799-805. PubMed PMID: 20795861.

yue L, Xie A, Bruzik KS, Frølund B, Qian H, Pepperberg DR. Potentiating action of propofol at GABAA receptors of retinal bipolar cells. Invest Ophthalmol Vis Sci. 2011 Apr 16;52(5):2497-509. Print 2011 Apr. PubMed PMID: 21071744; PubMed Central PMCID: PMC3088546.

Book Chapters 07/01/10 – 06/30/11

Alio JL, Azar DT. Management of Complications in Refractive Surgery. Gardners Books, 2010.

Birnbaum AD, Goldstein DA. Intermediate uveitis. In: Garg SJ. Uveitis. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2011.

Civelek ML, Saraiya N, Goldstein DA, Tessler HH. Hyper-sensitivity uveitis. In: Duane TD, Tasman W, and Jaeger EA. Duane’s Ophthalmology. Philadelphia: Lippincott Williams & Wilkins, 2011. Internet resource.

Gilbert M, Goodwin JA. Neuro-ophthalmology of the Afferent Visual System in Aging. In: Albert ML and Knoefel JE. Clinical Neurology of Aging. New york: Oxford university Press, 2011.

Goldstein DA. How do I diagnose and treat Fuchs Het-erochromic Iridocyclitis. In: Foster S. Curbside Consultation in Uveitis 49 Clinical Questions. SLACK Inc., 2011.

Goodwin JA. Leber’s Hereditary Optic Neuropathy. In: Neu-robase. Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman SG, eds. First published in 1994, updated annually.

Goodwin JA. Orbital Inflammatory Pseudotumor and Tolosa Hunt Syndrome. In: Neurobase. Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman SG, eds. First pub-lished in 1994, updated annually.

Goodwin JA. Temporal Arteritis. In: Neurobase. Arbor Pub-lishing Co., Gilman S, Goldstein GW, and Waxman SG, eds. First published in 1994, updated annually.

Goodwin JA. Transient Visual Loss. In: Neurobase. Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman SG, eds. First published in 1994, updated annually.

Goodwin JA. Vogt-Koyanagi-Harada Disease. In: Neurobase. Arbor Publishing Co., Gilman S, Goldstein GW, and Waxman SG, eds. [CD-ROM based computerized Textbook of Neu-rology] First published in 1994, updated annually.

Goodwin, JA: Clinical Neuro-ophthalmology. In: MedLink Neurology. San Diego, CA: MedLink Corp., 1990. <http://www.medlink.com/user/MedLinkLogin.ASP>

Hariprasad SM, Mieler WF. Antibiotics. In: Nguyen QD, Rodrigues EB, Farah, Eid M, and Mieler WF, eds. Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/Elsevier, 2010.

Kang-Mieler JJ, Kiernan DF, Mieler WF: Drug Delivery to the Posterior Segment. In: Duane TD, Tasman W, and Jaeger EA. Duane’s Ophthalmology. Philadelphia: Lippincott Williams & Wilkins, 2011. Internet resource.

Kang-Mieler JJ, Mieler WF. Thermo-sensitive hydrogels. In: Nguyen QD, Rodrigues EB, Farah, Eid M, and Mieler WF, eds. Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/Elsevier, 2010.

Klesert TR, Lim JI. Anti-vEGF treatment for age-related macular degeneration. In: Holz FG and Spaide RF. Medical Retina. Berlin: Springer, 2010.

Knepper PA, Nolan MJ, Yue BYJT. CD44 and Primary Open Angle Glaucoma. In: Schacknow PN and Samples JR. The Glaucoma Book A Practical, Evidence-Based Approach to Patient Care. New york: Springer, 2010.

Knepper PA, Nolan MJ, Yue BYJT. How the Revolution in Cell Biology Will Affect Glaucoma: Biomarkers. In: Schac-know PN and Samples JR. The Glaucoma Book A Practical, Evidence-Based Approach to Patient Care. New york: Springer, 2010.

Krakauer M, Azar DT. Bacterial Keratitis. In: Melki SA, Fava MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc., 2011.

Lin A, Steinert RF. Intraoperative floppy iris syndrome. In: Levin LA and Albert DM. Ocular Disease Mechanisms and Management. [Philadelphia]: Saunders/Elsevier, 2010.

Lin RC, Mieler WF, Wirostko WJ: Epiretinal Membrane. In: Quiroz-Mercado H, Kerrison JB, Alfaro DV III, Mieler WF, and Liggett PE, eds. Macular Surgery. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health, 2011.

Lin RC, Mieler WF. Retinal toxicity of systemic and topical medications. In: Nguyen QD, Rodrigues EB, Farah, Eid M, and Mieler WF, eds. Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/Elsevier, 2010.

Naithani R, Mehta RG, Shukla D, Chandersekera SN, Mo-riarty RM. Antiviral Activity of Phytochemicals: A Current Perspective. In: Watson RR, Zibadi S, and Preedy VR. Dietary Components and Immune Function. Totowa, NJ: Humana, 2010.

Nguyen QD, Rodrigues EB, Farah ME, and Mieler WF, eds. Retinal Pharmacotherapy. [Maryland Heights, MO]: Saunders/Elsevier, 2010.

Porter IW, Azar DT. Correction of astigmatism by laser keratectomy. In: Henderson BA and Gills JP. A Complete Surgi-cal Guide for Correcting Astigmatism: An Ophthalmic Manifesto. Thorofare, NJ: SLACK Inc., 2011.

Putterman AM. Cheek midface lift. In: Levine MR. Manual of Oculoplastic Surgery. Thorofare, NJ: SLACK Inc., 2010.

Putterman AM. Muller’s Muscle-Conjunctival Resection. In: Levine MR. Manual of Oculoplastic Surgery. Thorofare, NJ: SLACK Inc., 2010.

Quiroz-Mercado H, Kerrison JB, Alfaro DV III, Mieler WF, Liggett PE, eds. Macular Surgery. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health, 2011.

Saraiya Ny, Goldstein DA. Drug-induced uveitis. In: Garg SJ. Uveitis. Philadelphia: Wolters Kluwer Health/Lippincott Wil-liams & Wilkins, 2011.

Porter IW, Azar DT. Corneal Topography. In: Melki SA, Fava MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc., 2011.

Schmidt-Erfurth u, Williams GA, and Mieler WF. Encyclope-dia of Ophthalmology. Berlin: Springer, 2011.

Shukla Sy, Kiernan DF, Lim JI. Role of anti-vEGF thera-pies in neovascular AMD: what the clinical trials tell us. In: Campbell EJ and McMann LM. Macular Degeneration: Causes, Diagnosis, and Treatment. Hauppauge, Ny: Nova Science Pub-lishers, 2010.

Tu EY. Fungal Keratitis. In: Melki SA, Fava MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc., 2011.

Tu EY. Acanthamoeba Keratitis. In: Melki SA, Fava MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc., 2011.

Viana MA, Wynn HP. Algebraic Methods in Statistics and Probability II: AMS Special Session Algebraic Methods in Statistics and Probability, March 27-29, 2009, University of Illinois at Urbana-Champaign, Champaign, IL. Providence, RI: American Mathematical Society, 2010.

Wong JJ, Azar DT. Stromal Dystrophies. In: Melki SA, Fava MA. Cornea and Refractive Atlas of Clinical Wisdom. Thorofare, NJ: SLACK Inc., 2011.



10

Wu C-W, Ellenberg D, Chang J-H. Corneal angiogenesis and lymphangiogenesis. In: Levin LA and Albert DM. Ocular Disease Mechanisms and Management. [Philadelphia]: Saun-ders/Elsevier, 2010.

yannuzzi LA, Ed., The Retinal Atlas, Benson WE, Freund KB, Green WR, Hackel R, McDonald HR, Mieler WF, Shields CL, Shields JA, Trese MT, Contributors. The Retinal Atlas. [Philadelphia]: Saunders/Elsevier, 2010.

ARVO Meeting Abstracts April 22, 2011

Al-Ghoul KJ, Williams DK. Secondary suture branch forma-tion in rat lenses. ARvO Meeting Abstracts 2011;52:1537.

Bakhtiari P, Welder J, Chan C, de la Cruz J, Holland EJ, Dja-lilian AR. Surgical and visual outcomes of the type 1 Boston keratoprosthesis for the management of aniridic fibrosis syndrome in congenital aniridia. ARVO Meeting Abstracts 2011;52:332.

Cao D, Sun H, Lee BB. The weighting of rod and cone inputs to primate magnocellular ganglion cells. ARVO Meeting Ab-stracts 2011;52:4568.

Chang Q, Grassi MA. Fas mediated extrinsic apoptotic signaling in cone photoreceptors. ARVO Meeting Abstracts 2011;52:1811.

Cho Jy, Hu J, Chau FY, Lim JI. Association of spectral domain optical coherence tomography (SD-OCT) detected focal retinal thinning with systemic complications of sickle hemoglobinopathy. ARVO Meeting Abstracts 2011;52:1025.

Cortina MS, He J, Russ T, Bazan NG, Bazan HE. Topical treatment with neuroprotectin D1 increases corneal nerve regeneration after experimental surgery. ARVO Meeting Abstracts 2011;52:1982.

Crary MJ, Narayanan S, Visvesvara G, Joslin C, Tu E, Pan-jwani N, Hopkins A, Booton G, Fuerst P. Genotyping acan-thamoeba keratitis (AK) infections: Cytochrome oxidase I (COI) barcoding and phylogenetic analysis. ARVO Meeting Abstracts 2011;52:5832.

de la Cruz J, Cortina MS, Chang J, Azar DT. Scanning electron microscopy analysis of explanted keratoprostheses. ARvO Meeting Abstracts 2011;52:345.

Do Dv, Nguyen QD, Khwaja AA, Channa R, Sepah yJ, Boyer DS, Heier JS, Lim JI, Campochiaro PA, READ 2 Study Group. Aggressive anti-vEGF treatment is necessary to control dia-betic macular edema in many patients: Month 36 outcomes of the READ2 trial. ARvO Meeting Abstracts 2011;52:5332.

Ebihara L, Tong J, Chen T, Minogue PJ, Berthoud VM, Beyer EC. Different dominant effects of two cataract associated Cx50 mutants. ARVO Meeting Abstracts 2011;52:805.

Genead MA, Fishman GA. Presence and treatment of cys-toid macular edema in patients with choroideremia. ARVO Meeting Abstracts 2011;52:2130.

Grant P, Wanek JM, Zelkha R, Lim JI, Shahidi M. Wavefront aberration and fixation variations in normal subjects. ARvO Meeting Abstracts 2011;52:4460.

Han Ky, Chang J, Azar DT. Characterization of vegf-c induced lymphatic endothelial cell signaling by bioelectrical impedance analysis. ARvO Meeting Abstracts 2011;52:4827.

Hsia yC, Leal SM, Booton GC, Joslin CE, Cianciotto NP, Tu EY, Pearlman E. Acanthamoeba keratitis is exacerbated in the presence of intracellular legionella pneumophila. ARVO Meeting Abstracts 2011;52:5794.

Hsu M, Nolan M, Lin A. Indications and outcomes of scleral contact lens for severe ocular surface disease in the acute inpatient setting. ARvO Meeting Abstracts 2011;52:1960.

Jivrajka RV, Shammas M, Shammas JH. Improving second eye refractive error in patients undergoing cataract surgery. ARvO Meeting Abstracts 2011;52:2790.

Joslin CE, Tu EY. Contemporary annualized incidence rates of acanthamoeba keratitis. ARVO Meeting Abstracts 2011;52:1479.

Kang Mieler JJ, Jiang B, Perez-Luna v, Brey E, Mieler WF. PLGA nanospheres encapsulated within thermo-responsive hydrogel for ocular delivery of dexamethasone sodium phosphate. ARvO Meeting Abstracts 2011;52:467.

Kiernan DF, Chow CC, Singh R, Ulanski LJ, Lim JI, Blair NP, Mieler WF. Subsequent intravitreal triamcinolone is an effective treatment for I-125 plaque-associated retinopathy recalcitrant to intravitreal bevacizumab. ARVO Meeting Ab-stracts 2011;52:2105.

Knepper PA, McCarty RD, Mayer JP, Schwartz SN, Nolan MJ, Samples JR, Liebmann JM, Ritch R. Low molecular weight hyaluronic acid in POAG aqueous. ARVO Meeting Abstracts 2011;52:4627.

Knighton EA, Zoltoski RK, Roberts DK, Wilensky JT, Kuszak JR. Rate of increase in lens thickness decreases with age. ARVO Meeting Abstracts 2011;52:1540.

Krakauer M, Gupta S, Farooq AV, de la Cruz J, Cortina MS, Setabutr P. Oculoplastic considerations in kerato-prosthesis surgery. ARvO Meeting Abstracts 2011;52:342.

Kwak J, Movahedan A, Tadjvidi P, Aref P, Maumenee IH. Mendelian inheritance of strabismus in a rural community of northern Iran. ARvO Meeting Abstracts 2011;52:6359.

Liu y, Ripps H, Shen W. Localization of pannexin-mediated electrical coupling in the amphibian retinal cone pathway. ARvO Meeting Abstracts 2011;52:4556.

MajdiNasab M, Welder J, Pandya HK, Nassiri N, Djalilian AR. Fibrin glue and conjunctival-limbal transplant. ARVO Meeting Abstracts 2011;52:5136.

Malchow RP, Jacoby J, Booth SE, Alford ST, Qian H, Kreitzer MA. Testing the H+ hypothesis of feedback inhibition from horizontal cells to vertebrate photoreceptors: A tale of two techniques. ARvO Meeting Abstracts 2011;52:2568.

Maumenee IH, Alharbi AF, yanoga F, Azar NF. Natural history, genotype-phenotype correlation and differential diagnosis of the brittle cornea syndrome. ARVO Meeting Abstracts 2011;52:2397.

Mayer JP, Kasniunas A, McCarty RD, Schwartz SN, Yue BYJT, Knepper PA. Toll-like receptor 4, low molecular weight hy-aluronic acid and cytokine response in trabecular meshwork cells. ARvO Meeting Abstracts 2011;52:4652.

McCarty RD, Mayer JP, Schwartz SN, Knepper PA. Endoge-neous hyaluronidase and hyaluronidase inhibitors in POAG aqueous. ARvO Meeting Abstracts 2011;52:2430.

Mieler WF, Appel A, Turturro SB, Jiang B, Perez-Luna V, Brey E, Kang Mieler JJ. Efficacy of dexamethasone sodium phosphate thermo-responsive hydrogel treatment in endotoxin-induced uveitis model. ARVO Meeting Abstracts 2011;52:2752.

Milani By, Amirjamshidi H, Sagha H, Shafiq M, Movahedan A, Lavker RM, Yue BY, Djalilian AR. Limbal fibroblast condi-tioned media: A non-invasive treatment for limbal stem cell deficiency. ARvO Meeting Abstracts 2011;52:5144.

Movahedan A, Djalilian AR, Lavker RM, Yue BY. Notch activation and inhibition in corneal epithelial wound healing. ARvO Meeting Abstracts 2011;52:2033.

Namavari A, Chaudhary Sv, Sarkar J, yco L, Ma K, Jain S. Nerve regeneration in murine cornea. ARVO Meeting Ab-stracts 2011;52:1972.

Nayeb-Hashemi N, Patel S, Goldstein D. Anterior seg-ment ocular coherence tomography in the evaluation of scleral pathology. ARvO Meeting Abstracts 2011;52:1751.

Oltra EZ, Morris C, Birnbaum AD, Tessler HH, Goldstein DA. Chronic granulomatous uveitis in common variable im-munodeficiency. ARvO Meeting Abstracts 2011;52:4281.

Ostheimer TA, de la Cruz J, Cortina MS. Corneal graft thinning in Boston type 1 keratoprosthesis patients. ARVO Meeting Abstracts 2011;52:346.

Ozturk O, Ghanem RC, Han Ky, Rojas J, Kim DJ, Chang J, Azar DT. Semaphorin 7a promotes macrophage recruit-ment and angigenesis in experimental corneal neovascular-ization model. ARvO Meeting Abstracts 2011;52:6394.

Rha J, Genead MA, Bonci DM, Dubis AM, Schroeder B, Neitz M, Fishman GA, Carroll J. Imaging photoreceptor structure in achromatopsia patients using adaptive optics and spectral -domain optical coherence tomography. ARVO Meeting Ab-stracts 2011;52:4897.

Riaz KM, Djalilian AR, Bakhtiari P, Basti S. Natural course and treatment outcomes for limbal niche dysfunction. ARVO Meeting Abstracts 2011;52:5120.

Roberts DK, Ayyagari R, McCarthy BJ, Xie H, Wilensky JT, Davis F. Case-control study of long anterior lens zonule (LAZ) trait in first-degree relatives of African-American pro-bands. ARVO Meeting Abstracts 2011;52:2800.

Rose-Nussbaumer J, Goldstein DA, Acharya NR, Thorne JE, Shakoor A, yeh S, Rahman H, Flaxel CJ, Smith JR. uveitis in immunocompetent persons infected with human immunode-ficiency virus (HIv). ARvO Meeting Abstracts 2011;52:4274.

Schwartz SN, Beverley RM, Giovingo MC, McCarty RD, May-er JP, Knepper PA. Actin reorganization (CLANs) induced by sCD44-treatment in trabecular meshwork cells. ARVO Meeting Abstracts 2011;52:4634.

Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pa-van PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA. Hypot-ony in patients with uveitis: The multicenter uveitis steroid treatment trial. ARvO Meeting Abstracts 2011;52:4269.

Shafiq MA, Gemeinhart RA, Yue BY, Djalilian AR. De-velopment of an acellular human cornea to support the growth of corneal epithelial and stromal cells. ARVO Meeting Abstracts 2011;52:296.

Shah RJ, Chow CC, Hallak JA, Lim JI, Vajaranant TS. Reti-nal nerve fiber layer (RNFL) thickness analysis in sickle cell disease: Implications for glaucoma evaluation. ARVO Meeting Abstracts 2011;52:248.

Shahidi M, Wanek JM, Zelkha R. Enface imaging of photore-ceptor cell integrity. ARvO Meeting Abstracts 2011;52:2877.

Shukla D, Karasneh G, Bacsa S, Valyi-Nagy T. Up-regulation of syndecan expression may be A viral-induced mechanism for HSv-1 shedding. ARvO Meeting Abstracts 2011;52:5866.

11

Dr. Kenneth AlexAnDer retIreSSpanning 30 years, the esteemed vision scientist’s UIC

career includes important research, service and mentoring

Congratulations to Kenneth Alexander, PhD, Professor of Ophthalmology and Visual Sciences, who retired on November 15. Dr. Alexander leaves UIC with a legacy of important accomplishments in the three facets of academic life: teaching, research and service.

As an outstanding scientist, Dr. Alexander regards his greatest research achievement as clarifying the pathophysiology of inherited and acquired retinal diseases through research funded for 27 years by the National Eye Institute, National Institutes of Health (NIH). The impressive list of papers he has authored (more than 120 original articles in peer-reviewed publications) is evidence of a career dedicated to improving patient care through research. Dr. Alexander’s interest in developing noninvasive tests for assessing visual function was fostered during his 30 years of collaboration at UIC with Gerald Fishman, MD, a world-renowned authority on retinal disorders who was formerly Director of the Electrophysiology Service in uIC’s Department of Ophthalmology and Visual Sciences, and currently serves as Director of the Pangere Center for Inherited Retinal Diseases at the Chicago Lighthouse for People Who Are Blind or Visually Impaired.

An important mentor for Dr. Alexander, as he pursued his PhD in Psychology at the University of Washington, was the late Davida Teller, PhD, a pioneer in the study of infant vision. He also conducted research as an NIH Postdoctoral Research Fellow under the mentorship of Ralph Norman Haber, PhD, a leader in the psychology of visual perception, at the Center for Visual Science, University of Rochester.

Dr. Alexander held a faculty appointment at the Illinois College of Optometry and also taught part-time at the Art Institute of Chicago and DePaul university before joining uIC in 1981 as a Research Assistant Professor in the Department of Ophthalmology and Visual Sciences. He was promoted to Associate Professor in 1987 and to full Professor in 1994. In 2002 he was named the Marion H. Schenk, Esq. Professor of Ophthalmology and visual Sciences. Dr. Alexander also held two adjunct appointments at UIC in the Department of Psychology and in the Department of Bioengineering, illustrating the multidisciplinary nature of his research.

Dr. Alexander has also been an exceptional mentor and teacher throughout his career, guiding the careers of eight postdoctoral fellows, among them Neal Peachey, PhD, Professor at the Cole Eye Institute; Janet Szlyk, PhD, Executive Director of the Chicago Lighthouse; and Jason McAnany, PhD, Assistant Professor in UIC’s Department of Ophthalmology and Visual Sciences.

Dr. Alexander has been committed to academic service at UIC and throughout the vision science community. He is honored to have served as a regular member of the Biology of the Posterior Eye (BDPE) Study Section of the NIH and is proud of his leadership role in the Optical Society of America, including service as Chair of the Noninvasive Assessment of Visual Function Topical Meeting and Chair of the Division of Vision and Color.

Dr. Alexander is also a member of Phi Beta Kappa and Sigma Xi, a Fellow of the Optical Society of America, and an ARVO Silver Fellow.

Singa RM, Aakalu VK, Lin A, Setabutr P, Jain S. Ac-cessory lacrimal tissue gene expression. ARVO Meeting Abstracts 2011;52:5993.

Souteyrand G, Prat C, Yue B, Sapin V, Chiambaretta F. The beta-isoform of vitamin A receptors are expressed in hu-man corneal endothelium and epithelium. ARVO Meeting Abstracts 2011;52:6698.

Srivastava SK, Nguyen QD, Callanan D, Goldstein DA, Albini TA. The use of the fluocinolone acetonide (retisert) implant in patients with birdshot choroidopathy. ARVO Meeting Abstracts 2011;52:2751.

Suhler EB, Lowder Cy, Goldstein DA, Giles TR, Tes-sler HH, Lauer AK, Smith JR, Rosenbaum JT. Adalimumab (humira) for the treatment of refractory sight-threatening non-infectious uveitis: One year outcomes of an open-label prospective multicenter study. ARVO Meeting Ab-stracts 2011;52:6565.

Teng P, Blair NP, Wanek JM, yildirim I, Shahidi M. Longi-tudinal gradients of oxygen tension in the retinal vascula-ture of rat. ARvO Meeting Abstracts 2011;52:1732.

Thomas JG, Selner AN, Hetling JR. Exogenous currents delivered to the eye as A potential therapy: Computa-tional model comparing two electrode geometries in rat. ARvO Meeting Abstracts 2011;52:1864.

Tshionyi M, Shay E, Lunde E, Lin A, Han K, Jain S, Chang J, Azar D. Prevalence and distribution of hemangiogen-esis and lymphangiogenesis in pathologic corneas. ARVO Meeting Abstracts 2011;52:2017.

Tu EY, Shoff ME, Joslin CE. The addition of benzalkoni-um chloride to moxifloxacin confers anti-acanthamoebal activity in an in vitro model. ARVO Meeting Abstracts 2011;52:5830.

Vajaranant TS, Wu S, Torres M, Varma R. Demographic and geographic changes in the burden of visual impair-ment and blindness in the United States: 2010-2050. ARVO Meeting Abstracts 2011;52:4220.

Wanek JM, Teng P, Blair NP, Shahidi M. A new imaging method for assessment of inner retinal oxygen consump-tion in rat. ARvO Meeting Abstracts 2011;52:1348.

Wang AL, Grassi MA. Role of FAM18B in diabetic reti-nopathy. ARvO Meeting Abstracts 2011;52:2579.

Xie A, Pawlowski M, Feng F, Bruzik KS, Qian H, Pepper-berg DR. Enhancement of GABA-elicited responses of retinal ganglion cells by A photo-isomerizable compound. ARvO Meeting Abstracts 2011;52:1610.

yco L, Namavari A, Chaudhary Sv, Sarkar J, Jain S. Pro-teomic analysis of murine corneas during nerve regenera-tion. ARvO Meeting Abstracts 2011;52:2016.

ying H, Qiu y, Shen X, Shyam R, Yue BYJT. Establish-ment of inducible wild type and mutant myocilin-GFP-expressing RGC5 cell lines. ARVO Meeting Abstracts 2011;52:4597.

yue L, Pawlowski M, Bruzik KS, Qian H, Pepperberg DR. Photo-regulated activity of A tethered propofol derivative at GABAA receptors. ARVO Meeting Abstracts 2011;52:1166.


SILV

ER F

ELLOW

ARVO(Standing): David Pepperberg, PhD; Nalin Kumar, DPhil; Deepak Shukla, PhD; (Seated):Beatrice yue, PhD; Ken Alexander, PhD; and Mahnaz Shahidi, PhD


12

The National Eye Institute (NEI) of the National Institutes of Health has awarded uIC a $2.5 million grant for the uIC-NEI K12 Independent Clinical Vision Scientist Development Program. The project began in September and will continue through August 2016 under the leadership of Dr. Dimitri Azar, principal investigator for the project. uIC’s first-ever “K12 class” includes three MD, PhDs: Dr. Heather Moss, Assistant Professor of Ophthalmology and Director of the Neuro-Ophthalmology Research Program; Dr. yannek Leiderman, Director of the Retinal Bank Laboratory; and Dr. Iris Kassem, Assistant Professor of Ophthalmology in Pediatric Ophthalmology & Adult Strabismus Service.

The NEI’s program goal is to develop highly trained clinical scientists and patient-oriented investigators to address the nation’s biomedical, behavioral and clinical research needs in vision research. In turn, UIC has provided an academically rich and supportive environment that gives qualified early-stage clinician vision scientists a mentored learning experience to facilitate their career advancement and help them to become independent scientists. UIC is one of seven leading institutions in the U.S. operating a K12 program. The others include Duke University, John Hopkins University, the University of Pennsylvania, Washington university, Massachusetts Eye and Ear Infirmary, and University of California, Berkeley.

Translational research in vision science has become a top priority in the recruitment of faculty, the development of junior faculty into independent scientists, and in setting goals for the Department of Ophthalmology and Visual Sciences’ research program. According to Dr. Azar, the K12 program leverages the nascent success of the department in launching clinician scientist careers by building the positive resources already present in the department and strengthening them through development of a K12 curriculum mentored by leading scholars and researchers.

“One of the reasons we decided to pursue a K12 program was the growing number of faculty who benefited from our research resources to successfully apply for their own K awards: Sandeep Jain, Ali Djalilian, Charlotte Joslin and Deepak Shukla,” states Dr. Azar. “We realized that we have an exceptional environment for developing clinician scientists. Our proposal to NEI expanded on this strong foundation.”

UIC’s K12 training program has taken a needs-assessment approach to identify and address the barriers to achieving independence that confront clinicians who have demonstrated the skills needed to become independent clinician scientists. The program recognizes that research under the guidance of experienced mentors is key in order for investigators to transition to independence. So, the Department developed the K12 curriculum for mentoring scholars who have demonstrated readiness to be immersed in a research project.

UIC’s program has two goals: to establish a public university-public health agency partnership to train independent clinician vision scientists; and to provide scientific development, authentic mentorship and the professional development of the K12 scholars to ensure their transition to independence. Achievement of these goals will enable program scholars to become national leaders in vision health research, as well as the educators, mentors and role models for a new generation of vision health researchers.

HEATHER MOSS, MD, PhD

Dr. Moss is currently working on two projects as part of the K12 program. “I am continuing work that I started during my fellowship which demonstrated that vision is decreased in amyotrophic lateral sclerosis (ALS),” says Dr. Moss. “This is a devastating neuro-degenerative disease not previously thought to affect the visual pathways. The primary aims of this project are to determine why vision is decreased and if this decrease affects vision-related quality of life.”

In addition, Dr. Moss is starting a new project focused on vision loss due to the swelling of the optic disc in patients with high intracranial pressure, known as papilledema. “The aim is to identify examination and imaging markers that can predict the trajectory of vision (improving or declining) in a given patient,” notes Dr. Moss.

Dr. Moss sees definite career benefits in participating in the K12 program. “The grant is valuable because it will fund part of my salary and therefore allow me to dedicate more time to research,” says Dr. Moss. “This is especially important at this stage when I am starting new research projects that are not yet funded. Having this grant will springboard the projects and my career forward towards independent funding.”

Dr. Moss also sees her work in the K12 program benefitting patients. “My work with ALS patients may characterize a novel marker of disease that could guide future research and therapies,” states Dr. Moss. “And my work studying papilledema could help doctors (like myself) to appropriately refine therapeutic strategies for treatment of papilledema.”

UIc receIVes prestIgIoUs NeI K12 graNtDr. Dimitri Azar to serve as Principal Investigator

“this is especially important at this stage when I am starting new research projects that are not yet funded. having this grant will springboard the projects and my career forward towards independent funding.” —heather Moss, MD, PhD

13

YANNEK LEIDERMAN, MD, PhD

As part of the K12 program, Dr. Leiderman is researching retinal detachment and new treatments for restoring patients’ vision. Retinal detachment is a separation of the light-sensing structures from the back of the eye, resulting in profound loss of vision. Microsurgical techniques are utilized to restore the retina to its normal location.

“The most significant impediment to restoring vision is scarring of the retina, or proliferative vitreoretinopathy (PVR),” says Dr. Leiderman. “My laboratory studies the chemical signals that promote the formation of scar tissue following retinal detachment and eye trauma. By identifying the chemical messengers that result in PVR, we hope to discover new targets for medications that will block scar formation, allowing for restoration of vision in the most severe cases of retinal detachment.”

Vitreoretinal surgeons employ microsurgical techniques to restore function to tissues and structures among the most delicate and complex in the human body. Continual progress in understanding the chemical signals that maintain and nourish the retina provides new opportunities for restoring function and maintaining vision following retinal detachment. “The K12 program at UIC allows me to harness developments in laboratory research for continued progress in the surgical and medical treatment of the most complex eye diseases,” states Dr. Leiderman.

Dr. Leiderman notes that the K12 grant provides the support necessary to pursue laboratory investigations, as well as a framework for mentoring and access to shared resources, which are critical to establishing a successful research program and transitioning to an independent investigator.

IRIS KASSEM, MD, PhD

In describing the pediatric eye research she is conducting as part of the K12 program, Dr. Kassem explains, “A child’s eyes are not simply a smaller version of an adult’s eyes. There are fundamental differences in the structure and healing of the pediatric eye, as well as the development of a child’s vision, that make them unique. I am interested in elucidating these differences in pediatric eye disease and disorders and applying them to the care of our patients.”

Dr. Kassem also stresses the important role that mentors play in the K12 program. “I will have a mentor who is a successful clinician scientist, which will help me to develop the skills I need to one day be able to make my own contributions to advancing science and clinical care in pediatric ophthalmology. The wealth of information and experience my mentor has, not only in the science and techniques, but also in how to develop a research plan and write successful publications and grant applications, makes the program invaluable to my career development.”

Dr. Kassem’s ultimate goal in the K12 program is to bridge the gap between basic science and medicine in pediatric eye care. “Developing a greater understanding of the mechanisms involved in pediatric eye problems will allow us to apply the knowledge to modify our therapies, which can improve patient outcomes,” says Dr. Kassem. “If a child has poor vision that goes uncorrected, it can result in a lifetime of visual impairment. Conversely, if you fix a child’s vision, it can positively impact them for their entire life. The grant gives me a great opportunity to apply both the basic science and clinical aspects of my training to discovering better ways to diagnose and treat the serious pediatric eye problems I see in my patients.”

uIC’s first “K12 Class” (L-R): Kassem, Moss and Leiderman


14

physIcIaNs

Kelly Bui, MD Erica Oltra, MDJoshua Hou, MD Sara Huh, MD

Renu Jivrajka, MD Joann Kang, MD

SECOND YEAR

Janet Lim, MD Kavitha Sivaraman, MDRandee Miller, MD Senad Osmanovic, MD Kevin Patel, MD Adam Prickett, MD

FIRST YEAR

CORNEAPriti Batta, MD

GLAUCOMARobert McGlynn, MD

OCULOPLASTIC SURGERYVinay Aakalu, MD

PEDIATRIC OPHTHALMOLOGYKatherine Hare, MD

UVEITISScott Steiner, MD

RETINA Clement Chow, MD

RETINARajiv Rathod, MD

UVEITISJose Maria Garcia-Gonzalez, MD

UVEITISSarju Patel, MD

CLINICAL

FELLOWS

Elizabeth Grace, MD Rohan Shah, MDJennifer Hu, MD Mark Krakauer, MD, DPhil

Neema Nayeb-Hashemi, MD

Trucian Ostheimer, MD

THIRD YEAR

RESIDENTS

CORNEARoshni Vasaiwala, MD

15

IN traININg


16

FEDERALLY SPONSORED RESEARCH

Investigator Title Source

Alexander, Kenneth, PhD Visual Dysfunction in Retinal Degenerations National Eye Institute

Azar, Dimitri, MD, MBA Metalloproteinase Expression in Corneal Wound National Eye Institute

Azar, Dimitri, MD, MBA P30 Core Grant for vision Research National Eye Institute

Azar, Dimitri, MD, MBA UIC K12 Independent Clinical Vision Scientist Development Program National Eye Institute

Cao, Dingcai, PhD Rod-cone Interactions in Mesopic Vision National Eye Institute

Chang, Robert, PhD Inhibition of vEGF Receptor Dimerization and Signaling in Corneal Lymphangiogenes

National Eye Institute

Djalilian, Ali, MD Notch Signaling in the Corneal Epithelium National Eye Institute

Fortman, Jeffrey, DVM Ophthalmic Animal Facility Grant National Center for Research Resources

Grassi, Michael, MD Genomic and Genetic Studies of Diabetic Retinopathy National Eye Institute

Jain, Sandeep, MD Keratocyte Role in Guidance of Corneal Nerves National Eye Institute

Joslin, Charlotte, OD, PhD Local Food Environments and Disparities in Ovarian Cancer Survival National Institute on Minority Health and Health Disparities, Center of Excellence Program

McAnany, Jason, PhD Mechanisms Limiting Visual Performance in Retinal Degenerations National Eye Institute

Pepperberg, David, PhD Development Of Nanoscale Neuromodulating Platforms National Eye Institute

Shahidi, Mahnaz, PhD Retinal Image Quality In Retinal-Diseased Eyes National Eye Institute

Shahidi, Mahnaz, PhD Noninvasive Imaging of Chorioretinal Oxygen Tension National Eye Institute

Shahidi, Mahnaz, PhD Investigating Optical and Neural Causes of Vision Loss Department of Veterans Affairs

Shukla, Deepak, PhD Molecular Mechanism of HSv Entry and Spread National Institute of Allergy and Infectious Diseases

Shukla, Deepak, PhD Significance of Heparan Sulfate in HSv-1 Spread National Institute of Allergy and Infectious Diseases

Vajaranant, Thasarat, MD The Impact of Gender in Eye Diseases and Glaucoma National Eye Institute Building Interdisciplinary Research Careers in Women’s Health Program/ National Institute of Child Health and Human Development/Office of Research on Women’s Health

yue, Beatrice, PhD Cellular Processing of Optineurin, the Product of a Glaucoma Gene National Eye Institute

spoNsoreD research

17

FOUNDATION SPONSORED RESEARCH

Aakalu, Vinay, MD Development of a Prototype Temporal Fossa Glaucoma Shunt Illinois Society for the Prevention of Blindness

Aakalu, Vinay, MD Student Stipend Midwest Eye-Banks

Azar, Dimitri, MD, MBA Unrestricted Grant to Department Research to Prevent Blindness

Chang, Robert, PhD Collagen XVIII in Corneal Lymphangiogenesis Midwest Eye-Banks

Chaudhary, Shweta, MD Student Stipend Midwest Eye-Banks

Djalilian, Ali, MD Career Development Award Research to Prevent Blindness

Farooq, Asim Medical Student Eye Research Fellowship Research to Prevent Blindness

Grassi, Michael, MD Cellular Studies of Apoptosis in RP Using Small Molecule Screening and RNA Interference

Foundation Fighting Blindness

Hou, Joshua, MD Quantification of Adrenergic Receptor Subtypes in Human Muller Muscle and Correlation with Phenylephrine Testing in the Evaluation of Blepharoptosis

Illinois Society for the Prevention of Blindness

Hu, Jennifer, MD Effect of Hemodialysis on Intraocular Pressure and Ocular Perfusion Pressure


Jain, Sandeep, MD Numerical and Experimental Study of Collagen Cross-linking Treatment for Keratoconus

UIC Chancellor’s Discovery Fund for Multidisciplinary Research

Jain, Sandeep, MD Reinnervation After Corneal Surgery Eye Bank Association of America

Jivrajka, Renu, MD Early Detection of Functional Changes using Microperimetry on Patients with Subclinical Plaquenil Toxicity


Knepper, Paul, MD, PhD Activation of Innate Immune Toll-4 Receptor in POAG American Health Assistance Foundation

Pepperberg, David, PhD Plasmonic Nano-antennas to Enhance Light Sensitivity of Retinal Molecular Devices Designed for Vision Restoration

Doheny Eye Institute/Beckman Initiative for Macular Degeneration

Shahidi, Mahnaz, PhD Senior Scientific Investigator Award Research to Prevent Blindness

Shukla, Deepak, PhD Lew R. Wasserman Merit Award Research to Prevent Blindness

Shukla, Deepak, PhD Novel Peptides to Understand Herpetic Damage to Human Trabecular Meshwork via Actin Rich Nanotubular Structures

The Glaucoma Foundation

Vajaranant, Thasarat, MD Structural Testing in Advanced Glaucoma American Glaucoma Society

Vajaranant, Thasarat, MD Mentoring for the Advancement of Physician Scientists American Glaucoma Society

Zerfoss-Oltra, Erica, MD Correlation of Neurocognitive Function with Focal Macular Thinning in Sickle Cell


spoNsoreD research


18

Building on its success in treating young pediatric cornea patients, the Illinois Eye and Ear Infirmary now offers a Pediatric Cornea Section, launched in July 2010 with the recruitment of Dr. Aisha Traish. She is joined by Dr. Iris Kassem, the newest addition to the Pediatric Ophthalmology and Adult Strabismus Service, headed by Dr. Nathalie Azar. The stories offered here are a sample of how young lives can be changed with the gift of cornea transplants.

Catherine was just a toddler when she began to have vision problems. “She started running into things,” recalls her mother, Crissie. “She couldn’t see the faces of other kids and didn’t even recognize her own sister.” Catherine also had difficulty identifying household objects, even though they were large and close by.

In September 2007, at the age of two years old, Catherine was examined by Dr. Sandeep Jain, Director of UIC’s Corneal Neurobiology Laboratory. Both of her corneas were cloudy, which explained her impaired vision. “Based on a slit lamp biomicroscopy examination, we diagnosed her as having Congenital Hereditary Endothelial Dystrophy (CHED),” notes Dr. Jain. In this condition, the cornea absorbs water due to the disease of the cells that line its back surface, causing the cornea to swell up and lose its transparency, thus impairing vision.

“Given that Catherine’s impaired vision was now affecting her development, the family consented to have us perform corneal transplantation in both eyes,” says Dr. Jain. The right eye was operated on in September 2008 and the left eye in January 2009.

Prior to surgery Catherine was barely able to see 20/200 during vision testing, indicating that her vision efficiency was just 20%. At her most recent visit she could see 20/30 with glasses, meaning that her vision is now at 90%.

Today Catherine is an active five year old. “She’s doing great,” says her mom Crissie. “She would have lost her sight without the organ/tissue donation. It has made a 100% difference in what her life would be. She’s a normal kid.”

Liliana first came to see Dr. Elmer Tu, Director of Cornea Service, as a second opinion referral when she was just two weeks old. She was born with Peters Anomaly, a disorder that causes central corneal clouding, often with an attachment of the lens to the back of the cornea. She was afflicted in both eyes and her parents had been told that she needed immediate corneal transplants. Corneal transplants,

however, carry a high risk of rejection and failure in children.

“We were so happy with Dr. Tu,” exclaims Liliana’s mother, Kimberly. “We had seen four other cornea surgeons. But we chose UIC and Dr. Tu because it was the best fit for our family.”

At around six months, however, Liliana began to develop searching movements of the eye, indicating that her visual progress was slowing. Dr. Tu elected to remove a portion of the iris in her left eye in January 2006 to give her a new pupil in the area of clearest cornea. The iris in her right eye was operated on in September 2009.

“At the age of four her right eye appeared to improve enough anatomically that we started to consider corneal transplantation,” notes Dr. Tu. After much consultation, a corneal transplant was performed on Liliana in April 2010. “She has regained some function in this eye over the past year and is able to make out colors and images. Challenges still remain ahead for this eye, but so far she has done well,” says Dr. Tu. Adds mom Kimberly, “Dr. Tu cannot believe how great she is doing with the corneal transplant. Liliana can navigate spaces very well and can tell an eye chart from 10 feet away. We’re amazed at how well she is doing.”

Kimberly points out that she wasn’t a donor before Liliana’s experience, and didn’t think much about it when getting her driver’s license renewed. But she is a donor today. “Somebody helped my child and hopefully someday I can help someone else. A donation gave my daughter the opportunity to be able to see.”

Donovan was also born with Peters Anomaly, which affected both of his corneas, although the right eye was more severe.

“We waited for him to grow a little bit until he was two or three months old, and then tried a rotational corneal transplant in the right eye,” says Dr. Ali Djalilian, Director of the Stem Cell Research Laboratory. “This is where we take his own cornea and rotate it so the scar moves out of the center of the vision. We did this because we knew his chance of success with a regular corneal transplant would be very low.”

Unfortunately, the transplant did not work very long and within a few months it failed. At this point Dr. Djalilian asked Dr. Jose de la Cruz, Director of the Keratoprosthesis Program, to step in and he elected to perform an artificial cornea transplant in Donovan’s right eye when he was nine months old. This was very successful in helping to restore vision in the right eye, but recently Donovan required a second corneal transplant.

“Donovan is doing well,” says his mother Alicia. “He wouldn’t be able to see without the donor tissue. When you’re a donor, it opens up so many possibilities for families.”

tIssUe DoNors chaNge FoUr yoUNg lIVes ForeVerthe gift of sight gives patients a brighter future

19

Amaris developed what her pediatrician thought was a severe case of pink eye. When a cataract was discovered in her right eye, Amaris’ parents took her to see Dr. Debra Goldstein, Director of UIC’s uveitis Service. Just shy of her fifth birthday, Amaris was diagnosed with chronic uveitis, an inflammation that Dr. Golstein described as being akin to “arthritis of the eye.” According to Amaris’ mother, Crystal, Dr. Goldstein explained that the uveitis was treatable but not curable, and would require Amaris to take several different types of medication daily.

“Dr. Goldstein did all she could to keep Amaris’ eyesight,” recalls Crystal. Dr. Goldstein did five of the six eye surgeries that Amaris has undergone, with the first surgery at age five on her right eye.

In 2009 Amaris was diagnosed with glaucoma. Dr. Goldstein referred Amaris to UIC’s Dr. Jacob Wilensky, Director of Glaucoma Service, who performed a shunt procedure in November 2009. During this operation Amaris received donated sclera (eye white) tissue. Until Amaris’ parents were contacted earlier this year to invite their daughter to appear in the Illinois Eye-Bank poster, they didn’t realize that Amaris had been a recipient of donor tissue.

As a result of her positive experience, Amaris has decided to write a book to spread the word about the importance of organ/tissue donation. She also reached out to her donor’s family with a poem titled The Gift of Sight, which reads in part:

“WITH My EyES I CAN SEE

THIS MOST PRECIOuS GIFT yOuR LOvED ONE GAvE TO ME

THEy DIDN’T KNOW ME FROM ANyONE ELSE

BuT WHAT THEy GAvE TO ME vALuES MORE THAN WEALTH”

young uIC patients (clockwise from top): Donovan, Catherine, Liliana

and Amaris

Notes Crystal, “Amaris lost very little sight, but enough to be a voice and an advocate for a great cause.”

Today Amaris is a busy 12-year-old girl who is on her school’s honor roll and recently placed as a runner-up at the Miss Pre-Teen Chicago pageant, snagging the Most Photogenic award. Crystal points out that one day Amaris hopes to help someone else with an organ donation.

“It’s a blessing to have people who are willing to donate,” says Crystal.

The efforts of the Illinois Eye Bank to encourage organ and tissue donation were instrumental in the lives of these four young people.


20

Contact Lens

Charlotte Joslin, OD, PhD Corneal Refractive Power Post Refractive Surgery

Charlotte Joslin, OD, PhD Local Food Environments and Disparities in Ovarian Cancer Survival

Ellen Shorter, OD; C. Joslin Contact Lens Parameters in Keratoconus Patients at uIC, Illinois Eye and Ear Infirmary

Cornea

Ali Djalilian, MD Changing the Fate of Skin Epithelial Cells Grown on Human Amniotic Membrane

Erica Oltra, MD Assessment of Quality of Life in Patients with Tearing Disorders

Ellen Shorter, OD; J.de la Cruz; C. Joslin

Longitudinal Evaluation of Boston Keratoprosthesis

Joel Sugar, MD Compassionate use of the Ophtec 311 Artificial Iris Lens Implant

Joel Sugar, MD Cornea Donor Study - 10 year follow-up

Jose de la Cruz, MD Evaluation, Management and Clinical Outcomes of Patients Who underwent Keratoprosthesis for visual Rehabilitation

Glaucoma

Thasarat Vajaranant, MD; J. Wilensky; M. Lunde

Comparing the Effectiveness of Treatment Strategies for (Primary) Open-Angle Glaucoma

Thasarat Vajaranant, MD Structural Assessment in Glaucoma

Thasarat Vajaranant, MD Surgical Menopause and Risk for Premature Aging of the Optic Nerve and Glaucoma

Jacob Wilensky, MD Clinical Experience with Transscleral Laser Cyclotherapy

Neuro-Ophthalmology

Heather Moss, MD, PhD A Phase 1-Open-label, Dose Escalation Trial of QPI-1007 Delivered by Single Intravitreal Injection to Patients with Optic Nerve Atrophy (Stratum I) and Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II)

Heather Moss, MD, PhD Afferent Visual Function in Amyotrophic Lateral Sclerosis

Heather Moss, MD, PhD Prospective Study to Determine the Proportion of Patients with Isolated Third, Fourth and Sixth Nerve Palsies of Microvascular versus Non-Microvascular Etiology

Heather Moss, MD, PhD Retrospective Evaluation of Optical Coherence Tomographic Imaging of Optic Nerve Head Evaluation

Oculoplastic Surgery

Vinay Aakalu, MD Lacrimal and Accessory Lacrimal Tissue Gene Expression

Vinay Aakalu, MD Ocular Trauma Score and Visual Acuity Outcomes in Ocular Paintball Injuries

Veena Kulchaiyawat, MD Assessment of Visual Functioning and Quality of Life Before and After Ptosis Repair

Mark Krakauer, MD, DPhil; P. Setabutr Oculoplastic Considerations in Keratoprosthesis Surgery

Mark Krakauer, MD, DPhil; P. Setabutr Roof Pad Sculpting in Upper Blepharoplasty

Ramesh Singa, MD, DPhil; P. Setabutr Elemental Peri-Orbital Tissue Gene Expression Analysis

Ramesh Singa, MD, DPhil; P. Setabutr Eyelid and Oculoplastic Surgical Outcomes and Analysis

Pediatric Ophthalmology & Adult Strabismus

Iris Kassem, MD, PhD Positional Changes in Preoperative Measurements for Pediatric Cataract Surgery

clINIcal INVestIgatIoNs and trIals

21

Retina

Renu Jivrajka, MD; W. Mieler Early Detection of Functional Changes using Microperimetry in Patients with Subclinical Hydroxychloroquine (Plaquenil) Toxicity

Jennifer Lim, MD; Y. Leiderman F. Chau; L. Ulanski

Effect of Diabetes Education during Retinal Ophthalmology visits on Diabetes Control (Protocol M)


Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema (Protocol I)


A 1-Month, Multicenter, Observational Study to Evaluate the Degree of Ocular Inflammation Associated with Pars Plana Vitrectomy


A Double-Masked, Randomized, Active-Controlled Phase-3 Study of the Efficacy and Safety of Intravitreal Administration of vEGF Trap-Eye in Patients with Diabetic Macular Edema

Jennifer Lim, MD; L. Ulanski A Pilot Study in Individuals With Center Involved DME undergoing Cataract Surgery (Protocol P)


A Randomized, Double Masked, Controlled Phase 3 Study of the Efficacy, Safety and Tolerability of Repeated Intravitreal Administration of vEGF Trap-Eye in Subjects with Macular Edema Secondary to Central Retinal vein Occlusion (CRvO)

Jennifer Lim, MD A Retrospective Case Series to Assess the Efficacy of Anti-vEGF Therapy in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion


An Evaluation of Intravitreal Ranibizumab for vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (Protocol N)

Jennifer Lim, MD; L. Ulanski An Observational Study in Individuals with Diabetic Retinopathy Without Center-Involved DME undergoing Cataract Surgery (Protocol Q)


An Open-Label Study of the Safety and Tolerability of Combining IBI-20089 (Triamcinolone Acetonide Intravitreal Injection) When Used Adjunctively with Lucentis 0.5 mg Intravitreal Injection in Subjects with Subfoveal Neovascular Age-Related Macular Degeneration

Jennifer Lim, MD; L. Ulanski Comparison of Time Domain OCT and Spectral Domain OCT Retinal Thickness Measurement in Diabetic Macular Edema (Protocol O)

Jennifer Lim, MD; L. Ulanski Evaluation of visual Acuity Measurements in Eyes with Diabetic Macular Edema

Jennifer Lim, MD; L. Ulanski Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment To Panretinal Photocoagulation for Proliferative Diabetic Retinopathy (Protocol J)

Jennifer Lim, MD; L. Ulanski Maculopathy

Jennifer Lim, MD Optical Coherence Tomographical Retinal Thickness Analysis of Sickle Cell Patients

Jennifer Lim, MD; L. Ulanski Ranibizumab Therapy For Choroidal Neovascularization Associated With Angioid Streaks

Rohan Shah, MD; J. Lim Retinal Degenerations and Their Effect on Retinal Thickness

Lawrence Ulanski, MD A 3-year, Phase 3, Multicenter, Masked, Randomized, Sham-Controlled Trial to Assess the Safety and Efficacy of 700 ug and 30 ug Dexamethasone Posterior Segment Drug Delivery System (DEX PS DDS) Applicator System in the Treatment of Patients with Diabetic Macular Edema

Lawrence Ulanski, MD Age-Related Eye Disease Study 2 (AREDS2): A Multi-Center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Long-Chain Polysaturated Fatty Acids Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) in Age-Related Macular Degeneration

Lawrence Ulanski, MD Home vision Monitoring in AREDS2 for Progression to Neovascular AMD using the ForeseeHome Device

Uveitis

Kelly Bui, MD; D. Goldstein; J.M. Garcia-Gonzalez; S. Patel

Directed Conjunctival Biopsy in Ocular Sarcoidosis

Debra Goldstein, MD Characteristics, Natural History and Treatment of Uveitic Diseases at the University of Illinois at Chicago, Uveitis Service

Debra Goldstein, MD Long Term Follow-Up of Patients Who Participate in the Multi-Center Uveitis Steroid Treatment (MUST) Trial Follow-up Study (FS)

Debra Goldstein, MD; S. Patel Macular Configuration Predisposing to CME in uveitis

Debra Goldstein, MD; S. Patel Observation of Chronic Uveitis Longitudinally Across 4 Regions (OCULAR)

Debra Goldstein, MD Phase III, Multinational, Multicenter, Randomized, Double-Masked Study Assessing the Safety and Efficacy of Intravitreal Injections of DE-109 (three doses) for the Treatment of Active, Non-Infectious uveitis of the Posterior Segment of the Eye

Debra Goldstein, MD; A. Birnbaum; S. Patel

Simultaneous Bilateral Acute Anterior uveitis: Prevalence, Etiology and Prognosis in a Retrospective Study

Debra Goldstein, MD; S. Patel Standardization of Uveitis Nomenclature

Filled rows indicate: Open patient enrollment | Red indicates a sponsored clinical trial.

To learn more about any of these investigations and trials, including how to refer patients, please call 312-996-6590.


22

$100,000+

Mr. Gerhard Cless *Cless Family FoundationFoundation Fighting BlindnessHope for Vision Research to Prevent Blindness, Inc.

$50,000-99,999

Alcon Laboratories, Inc.

$20,000-49,999

Glaucoma Foundation, Inc. Mr. Gary R. Janko *Midwest Eye-Banks and Transplantation Center

Dr. John H. Panton *Dr. Allen Putterman *Rice Foundation Dr. Howard H. and Mrs. Tena Tessler *Mrs. Marie E. Wilkinson * †

$10,000-19,999

Solna A. Braude **Braude Foundation Dr. R. Mark and Mrs. Monica J. W. Hatfield *Illinois Society for the Prevention of Blindness

Dr. Pete A. and Mrs. Diane Greanias Lagouros *

$5,000-9,999

Arch W. Shaw Foundation Dr. Jettie M. Burnett **Edwin F. Schild Foundation Mrs. Diane K. Henry *Dr. Paul K. and Mrs. Ruth Morimoto **Omega Surgery Centers, LLC Mr. Steven B. Ross *Don M. Smart, MD *

$2,500-4,999

Dr. Dimitri T. and Dr. Nathalie F. Azar *DuPage Eye Associates, SC DBA M. Raichand MD, SC

DuPage Ophthalmology Dr. Daniel B. Feller **Ms. Anne C. Haffner in honor of Dr. Paul Knepper **

Mr. Gerald and Mrs. Marsha Kaplan in memory of Arnold M. Kaplan **

Ms. Elaine N. Kirk **Dr. Steven P. and Mrs. Melinda Koenig **Dr. Sao Cheng Liu **Dr. Sao Jang Liu *David M. Lubeck MD **Harvey K. Minatoya MD **Dr. John J. Moy **Mr. Bradley A. Tisdahl in memory of Mr. Barry Thomas McNamara **

Mr. John Veleris *

$1,500-2,499

Mr. Julian L. and Mrs. Joan S. Berman *Mr. Barry J. and Mrs. Barbara P. Carroll * The Carroll Foundation

Dr. David J. Fuerst and Mrs. Marie M. Perrelli-Fuerst

Dr. Edward J. Goldman IOP, Inc. Dr. Paul A. Knepper and Dr. Zibute Zaparackas *

Dr. John J. McGetrick **Medical Eye Services, Ltd. David D. Morimoto MD

hoNor roll oF DoNors

Illinois Eye Fund

OFFICERS

CHAIR, Dimitri Azar, MD, MBAvICE PRESIDENT, Samuel J. Cascio, DDSTREASuRER, Julian L. BermanSECRETARy, Irene T. Schoenberg

MEMBERS

Barry J. CarrollGerald Fishman, MDWilliam Jackson Jones, DDSSteven P. Koenig, MDBarry MalkinFrank I. Mendelblatt, MDMarilyn T. Miller, MDSteven B. RossGeorgia RouloSriram Sonty, MDVan C. StoneJoel Sugar, MDPatricia WagerJacob Wilensky, MD

EMERITUS

Harris Ripps, PhD, DScDiane Kraft Henry

EX-OFFICIO

Julie Daraska

ADVANCEMENT

David J. Eaton

Illinois Eye Fund Board. (L to R): Mr. Julian Berman, Dr. Samuel Cascio, Dr. Marilyn Miller, Ms. Georgia Roulo, Dr. William Jackson Jones, Ms. Pat Wager, Dr. Dimitri Azar, and Mr. Barry Carroll

23

Josipa Paska George R. Reiss MD Dr. Harris and Mrs. Jeanne RippsDr. William L. Schey **

Ms. Dorothy T. Tannenbaum

$1,000-1,499

Dr. Daniel C. AlterDr. Phillip D. and Mrs. Vicki A. Alward **Mr. Albert and Mrs. Doreen BarskyBatavia Lions Club Dr. Harit K. Bhatt and Ms. Anamika DasMrs. Andrea BrombergDr. Steven B. Cohen Dr. Anne L. ColemanMr. Serge D. De Bustros in honor of Dr. Dimitri T. Azar

Dr. Deepak P. and Mrs. Deepak P. Edward*

Ms. Anita S. Gerber and Dr. Joel Sugar Dr. Morton F. and Mrs. Myrna Goldberg *Dr. Sherwin Isenberg Lee M. Jampol, MDBrian C. Joondeph, MDJennifer I. Lim, MDDr. Irwin Menachof Mr. William J. and Mrs. Jean M. O’NeillMrs. Deloras A. PembertonThe Philip and Myn Rootberg Foundation Mr. Javier RubinsteinDr. Veeral S. ShethMr. Gregory L. and Mrs. Carlene G. Smith*

South Holland Lions Club Strauss Foundation, Inc. Mr. Robert B. and Mrs. Sheri B. Tisdahl in memory of Ms. Roslyn Davis

UBS Matching Gift on behalf of Mr. Bradley Tisdahl

$500-999

Dr. Alan J. and Mrs. Jennifer K. AxelrodNorman P. Blair, MDDr. Samuel J. Cascio *Ms. Mary E. Davidson Dr. Jesse M. and Dr. Libbie B. De Leon Globetrotters Government Sector, LLC Nancy A. Hamming MDDr. Alice O. and Mr. James F. KeaneDr. Timothy T. and Mrs. Kay McMahonMrs. Jenifer Mason RobbinsKathleen M. Scarpulla MDMr. LeRoy and Mrs. Albina Schalansky Mr. Ira J. and Mrs. Beverly W. SchulmanDr. Joanne ShenSynthesDr. Mark O. M. and Mrs. Petrina C. TsoProf. Elmer y. TuDr. Thasarat S. Vajaranant Ms. Patricia S. Wager *Dr. Robert S. and Mrs. Shifri A. WeinbergDr. Robert D. WertzMs. Chai S. WilenskyDr. Jacob T. Wilensky

$250-499

Dr. Lawrence I. and Mrs. Patricia Chapman Dr. Robert A. Copeland Jill A. Foster MD Robert E. Gorsich MDDr. Marc F. GreenbergMr. Donald L. LeoneDr. Miriam T. Schteingart Light Dr. Diosdado T. Lim Dr. Frank I. and Mrs. Katherine Mendelblatt

Dr. Floyd G. Miller Ashok R. Penmatcha MDMr. William D. PerkinsMs. Marcia PevsnerDr. Jose S. Pulido and Dr. Colleen A. Howe *Mr. James T. and Mrs. Karen C. Reid Dr. Alan V. and Mrs. Linda K. SpigelmanElvira Teel Trust †Mr. Georg G. ToftEnrique Garcia-valenzuela MD

up to $250

Mr. Shankarnaray AdapathyaMs. Doris Anderson in memory of The Reverend David D. Hancock

Mr. Charles L. BarskyMr. Gregory B. BeggsAbdhish R. Bhavsar, MD and Mary A. Bhavsar

Mr. John J. and Mrs. Phyllis A. Bierdz

Parent Petroleum Co. was recognized for its generous support of the Retina Chemical Genomics Lab, directed by Dr. Michael Grassi. Pictured (LtoR): Mark Potaczek; ysel Mancini, and Peter Mancini, all with Parent Petroleum Company; Dr. Dimitri Azar, Interim Dean of the uIC College of Medicine; Dr. Grassi and Dr. Mahnaz Shahidi, Vice Chair for Research.


24

Dr. Rebekah A. BraslowMrs. Marie J. BugajskiMr. Anthony ButtittaMs. Cynthia Caplin in memory of Ms. Barbara McDonald

Dr. Michael E. Carroll Mr. Ronald L. and Mrs. Lucy C. Chamberlain in memory of The Reverend David D. Hancock

Mr. Franklin A. and Mrs. Doralu ChanenMs. Gladys A. Charleston in memory of Ms. Deidre Redington

Chicago Cornea Consultants, Ltd.Dr. David M. and Mrs. Barbara L. CohenMr. L. Park and Mrs. Sharlene M. DavisDr. Naomi L. Ellenhorn-DavisDiscover Financial Services matching gift on behalf of Mr. Charles Barsky

Dr. Mohammed El MallahRandy J. Epstein, MD and Linda S. KatzBruce D. Fick, MDMr. Leo and Mrs. Lillian E. FlorosMr. Roger L. and Mrs. Susan E. Frick in memory of The Reverend David D. Hancock

Joseph B. Garber, MDBernardino Garcia, MD and Robyn M. GarciaDr. Bruce R. and Mrs. Moyra Dunne Garretson

Ms. Mary C. Gates in memory of Mr. James Zembron

Mr. Michael L. Gates in memory of Mr. James Zembron

Miss Elden GenitisMs. Anita S. Gerber and Dr. Joel Sugar in memory of Mr. Stellan C. Aker

Mrs. Sandra K. and Mr. Glen Gibbons in memory of The Reverend David D. Hancock

Mrs. Opal and Mr. Kenneth R. Glasco in memory of The Reverend David D. Hancock

The Honorable Sidney J. GoldsteinMs. Charlotte R. GoldwaterMr. Chris E. and Mrs. M. K. Goolsby in memory of The Reverend David D. Hancock

Mrs. Sylvia E. GreenbergPierre Guibor, MD *Mrs. Dorothy Hadrava in memory of Mr. James Zembron

Mr. Dean and Mrs. Nila Hemming in memory of The Reverend David D. Hancock

Charles C. Ho, MDDr. Paul I. and Mrs. Cindy Jo Homer

Mr. Richard A. and Mrs. Mary E. Howell Indian Camp Baptist Church in memory of The Reverend David D. Hancock

The Insurance House in memory of The Reverend David D. Hancock

Donald S. Jacobs, MDMrs. Beverly and Mr. J. C. Jones in memory of The Reverend David D. Hancock

Ronald A. Kalayta, MDDr. Richard V. and Mrs. Zoe KaufmanMr. William G. Keenan in memory of The Reverend David D. Hancock

Ms. Jane Kelly in memory of Mr. James Zembron

Mrs. Paula L. and Mr. Kenneth W. Kelly in memory of The Reverend David D. Hancock

Ms. Kate T. Kestnbaum *Mrs. Evelyn KiblerMs. Arlene M. KnappMrs. Iwanna A. and Mr. Lukasz Krynicki in memory of Mr. James Zembron

Mr. T. and Mrs. T. Kuzniarek in memory of Mr. James Zembron

Dr. Charlton Rex and Mrs. Janet M. LattaMrs. Ale B. and Dr. Eligijus P. LelisMs. Carolyn M. Leonard in memory of The Reverend David D. Hancock

Mrs. Patricia M. Livingston Mr. Tim and Mrs. Jennifer L. Lovell in memory of Mr. James Zembron

Dr. Paul Arthur MahlbergMs. Helorna N. McFall Mr. Donald E. McMahon in memory of Mr. James Zembron

Mrs. Mildred R. MonsenDr. Marcus and Mrs. Sue MuallemMr. Donald E. and Mrs. Elisabeth A. Murphy in memory of Mr. James Zembron

Mrs. Genie MurphyMrs. Arlene MusilMs. Jeanne Nelson in memory of The Reverend David D. Hancock

Mr. Anthony J. and Mrs. Anthony J. OnestoMs. Lynn Orschel Ms. Linda Osowski in memory of Mr. James Zembron

Mr. Todd R. OsterburMr. Richard PalandechDr. Robert W. and Mrs. Marika M. PantonMrs. Sally L. Pope *Mr. Anthony L. RainaldiProf. John T. and Ms. Sarah D. Ramsey Mr. James E. Rathmann in memory of Mrs. Elsie Rathmann

Ms. Jane W. RavidMr. Marvin Rogan in memory of Mrs.Laura L. Rogan

Dr. Alfred A. Rosenbloom Jr. and Mrs. Sarah R. Rosenbloom

Mr. David G. RosenfeldMr. Warner A. Rosenthal Mr. Thomas and Ms. Sharon S. Schaefer in memory of Mr. James Zembron

Mrs. Gloria B. Schall Joel A. Schulman, MD Mr. Richard L. and Mrs. Judith L. Schultz Mr. Stanley L. SchwartzMr. Lee S. SimonMrs. Debra W. Sinay *Ms. Barbara S. Spielman Hugo R. Steinitz, MDMr. Daniel S. SugarDr. Karen D. SumersMr. Terry A. and Mrs. Rosemary Summers in memory of The Reverend David D. Hancock

John B. Thompson, MDMr. Joe Till and Mrs. Janet Gonek in memory of Mr. James Zembron

Ms. Elissa TisdahlMr. Robert B. and Mrs. Sheri B. Tisdahl in honor of Dr. Howard Tessler

Ms. Charlene McSparin Troutman in memory of The Reverend David D. Hancock

Dr. Dana O. TroyerMs. Cynthia Buehring-Upchurch in memory of Leslie Julia Baber

Samuel J. Vainisi, DVMMs. Deborah Walens and Mr. John C. McCrosky in memory of Mr. James Zembron

Mr. Fred and Mrs. Janice Weissman Mr. Steve and Mrs. Bonnie Wheeler in memory of The Reverend David D. Hancock

Martha J. Willi, MDMr. J. L. and Mrs. Orline Williams† in memory of The Reverend David D. Hancock

Dr. Sherrie D. Williams Mrs. Maxine D. and Mr. Jerry L. Williamson in memory of The Reverend David D. Hancock

Willow Springs Lioness Club Mr. Michael J. and Mrs. Kathleen A. Worrall Dr. Beatrice y. yueMr. Tony ZamoraMr. Charles D. and Mrs. Debra Zis

* President’s Council** Chancellor’s Circle

up to $250 (continued)

25

Marie E. Wilkinson, a generous donor to the Illinois Eye Fund since 1988 when she made her initial gift in memory of her late husband, Herbert Wilkinson, passed away this past June. She was 100 years old. Herbert passed away in June 1988.

Marie and Herbert Wilkinson were partners in life in every way, including their philanthropy. Herbert was a longtime executive with Abbott Laboratories, where he began his career in 1930. He was president and director of Abbot Laboratories. He retired in 1971 and then served as president of the Board of the Clara Abbott Foundation, and as vice president of the Abbott Laboratories Fund.

Marie and Herbert met in Cincinnati and moved to Chicago when he joined Abbott. They settled in Lake Forest in 1957 and had three children, Carol Keenan of Chicago, Janet W. (Thomas M.) Leopold of Winnetka, and the late Herbert S. Wilkinson, Jr. Marie also leaves two grandchildren and five great-grandchildren.

Herbert Wilkinson’s association with the Department of Ophthalmology and visual Sciences started in the late 1980s as a patient. His philanthropy started soon afterwards, and he became deeply committed to the Department and its research and patient care programs. Upon his death, Marie continued Herbert’s devotion to the Department for another 25 years through continued philanthropy supporting a variety of research programs and equipment purchases.

Marie Wilkinson trained as a nurse and did part of her medical training in Appalachia. She was passionate about helping others and making a difference. As an avid gardener, she loved to see things grow and develop. Her desire to help others was demonstrated also by her volunteer activities with several organizations including her church, the First Presbyterian Church in Lake Forest, and the Boarder Babies program in Chicago.

According to Patricia Wager, former executive director of develop-ment at the University of Illinois Medical Center who worked with Mrs. Wilkinson since the late 1980s, “Helping people was a central part of Mrs. Wilkinson’s life. She demonstrated this wonderful qual-ity through her contributions to the Department of Ophthalmology and Visual Sciences to support eye research for 25 years in memory

of her husband. These gifts were instru-mental in helping the researchers develop new treatments and cures for eye disease and blindness. The positive impact of Mr. and Mrs. Wilkinson’s generos-ity is felt by patients now and in the future who will benefit from this research. Their legacy of helping lives on.”

Among the research programs that received support from Mrs. Wilkinson’s generous donations to the Illinois Eye Fund are the Photoreceptor Research Laboratory directed by David Pepperberg, PhD, the Ocular Virology Research Laboratory directed by Deepak Shukla, PhD, and the Retinal Circulation and Metabolism Laboratory directed by Norman Blair, MD Most recently, research funding has been provided to one of the Department’s young clinician scientists: Soledad Cortina, MD. Dr. Cortina’s research focuses on the study of corneal nerves and possible treatments that will speed corneal nerve recovery. In addition, Marie’s gifts made possible the acquisition of a state-of-the-art instrument to rapidly measure the concentration of proteins and other biomolecules in a variety of basic science experiments. FortéBio’s new Octet® RED96 System will foster new vision science discoveries.

“These are just a few examples of the important vision research activity that has been greatly aided by Marie Wilkinson’s generosity,” stated Dr. Dimitri Azar, Interim Dean of the College of Medicine, B.A. Field Endowed Chair of Ophthalmologic Research, and Professor and Head of the Department of Ophthalmology and Visual Sciences. “Mr. and Mrs. Wilkinson understood that research in vision and ophthalmology would improve the quality of care and quality of life for everyone suffering from vision loss or blindness, today and for generations to come. We are deeply indebted to them.”

The Illinois Eye Fund provides support for research, education and patient care in the Department of Ophthalmology and Visual Sciences. The Department leads in the diagnosis, management, and treatment of the most serious and complicated ophthalmologic cases. To make a gift, go to www.uic.edu/com/eye/WaysToGive or call 312-996-6590.

MarIe e. wIlKINsoNIn memory of our good and caring friend,


26

RENOVATIONS

A series of extensive renovations at the Illinois Eye and Ear Infirmary has resulted in much-improved treatment spaces for both patients and doctors. Renovations completed in 2011 include welcoming new reception areas, the addition of high-tech diagnostic equipment, and patient amenities such as comfortable new furniture and flat screen TVs in waiting areas. According to Agustin Lopez-Scala, Assistant to the Head of Ophthalmology and Visual Sciences, patient care areas for the Cornea, Contact Lens and Glaucoma Services, and the new Comprehensive Ophthalmology Faculty Practice, all underwent renovation.

The biggest expansion occurred in the Glaucoma Service, which went from 10 to 15 rooms and relocated from the second to the third floor of the Infirmary building. Besides a new reception and waiting

area, the Glaucoma Service now features seven rooms equipped with the new M&S Vision Testing System. This high-tech alternative to chart projectors is a computerized vision testing system that features a wide variety of charts, contrast sensitivity and multimedia functions. In addition, the Glaucoma Service now has two independent visual field testing rooms, a renovated technician suite and a new dedicated conference room.

“This renovation definitely benefits us all,” says Thasarat S. Vajaranant, MD, Assistant Professor of Ophthalmology and Director of Glaucoma Service. “It allows us to work more efficiently to deliver the best care. I personally received many positive comments from our patients.”

Other renovation highlights include the addition of four exams rooms in the Cornea Service. Each room is equipped with an M&S Vision Testing System. Contact Lens Service has relocated and has three new rooms, along with a special contact lens trial room outfitted with contact lenses and diagnostic equipment. The Comprehensive Ophthalmology Faculty Practice expanded from three to six exam rooms, plus a dedicated testing area. Each new room is equipped with

the M&S Vision Testing System. Comprehensive Ophthalmology also has a new reception and waiting area.

“The additional space has allowed us to increase volume while maintaining excellent care,” notes Pete Setabutr, MD, Assistant Professor of Ophthalmology and Director of Oculoplastic Surgery. “The improvements in the waiting area provide a relaxed and comfortable area for our patients.”

Big plans for 2012 include the entire renovation of the Pediatric Ophthalmology & Adult Strabismus Service, located on the second floor of the Infirmary building. The project includes a new reception and waiting area, eight exam rooms, one visual testing room, and four other clinical and administrative rooms. Also, six rooms on the second floor of the Infirmary building will be converted to physicians’ offices. These new spaces will be home to doctors who have been hired within the past two years and have not had permanent offices.

reNoVatIoNs & INNoVatIoNsnew cutting-edge equipment and renovated spaces benefit doctors and patients

Dr. Thasarat S. Vajaranant, Director of Glaucoma Service

Department of Ophthalmology & Visual Sciences

27

INNOVATIONS

Exciting new cutting-edge equipment was installed in 2011, with more scheduled to be in place in the coming year. In 2011, the department acquired a new Trabectome® unit for the Glaucoma Service. This FDA-approved surgical device allows for minimally invasive treatment of glaucoma that decreases pressure in the eye and stabilizes vision. The outpatient Trabectome® surgical procedure can lower pressure into the mid-teens and reduce the patient’s reliance on glaucoma medications, without subjecting the eye to the risks of a more invasive trabeculectomy.

The department is currently in the process of acquiring a femtosecond laser system for use in cataract surgery. This is breakthrough technology originally approved for refractive surgery, including LASIK procedures. However, the FDA has now approved the use of the system to include “cuts” in the cornea, including vertical and lamellar cuts. The possibilities for use now include, but are not limited

to, femtosecond keratoplasty, astigmatic keratoplasty, and Intacs for keratoconus.

The femtosecond laser differs from the traditional method of refractive surgery in a number of ways, using a near infrared light to create precise subsurface cuts. Traditionally, in refractive surgery ultraviolet light sources, such as the excimer laser, have been used for precise surface cuts on the cornea. These light sources were dependent on tissue properties to absorb the light. The femtosecond laser works independently of light tissue absorption, so photodisruption of deeper tissues is possible and the patient’s corneal anatomy (such as steepness, flatness or thickness of the cornea) does not interfere with the cuts. This leads to a more uniform treatment. In addition, femtosecond pulses are very short, of subpicosecond duration, which allows lower energy levels and aids in precision, decreasing collateral damage. The femtosecond laser system is expected to be ready to use by Ophthalmology’s surgeons, fellows and residents by June 2012.

Dr. Elmer Tu, Director of Cornea Service

Fellows and Residents

Dr. Norma Allemann and Dr. Wallace Chamon, both on the Department of Ophthalmology faculty of the Federal University of São Paulo, Brazil, are Visiting Professors for the 2011-2012 academic year.

Dr. Allemann’s research and clinical expertise includes ultrasonography and optical coherence tomography for anatomic evaluation of ocular structures in different clinical and surgical situations. She is an expert in and teaches ultrasound biomicroscopy, anterior segment ultrasound, anterior segment optical coherence tomography, ultrasound and optical biometry, and ocular ultrasound, as well as refractive surgery techniques.

While at UIC, Dr. Allemann will be collaborating with the Azar research group on the Total Eye Transplantation research project. Dr. Allemann is also working with the Retina Service to expand and improve our ultrasound clinical services. At the Cornea Service she will collaborate with projects in imaging keratoprosthesis. Dr. Allemann notes that she will participate in the Illinois Eye Review, as well as help by submitting papers originating from her research at UIC.

Dr. Chamon practices, teaches and conducts research in the areas of restoring corneal transparency, myopia and public health, and therapeutics of refractive errors. During his visit, he will collaborate with Dr. Dimitri Azar, Dr. Pier Cristoforo Giulianotti and Dr. Enrico Benedetti on the Robotics in Ophthalmic Surgery project. He will also work on the Corneal Biomechanics and Finite Element Modeling project with Dr. Azar, Dr. Sandeep Jain, Dr. Jose de la Cruz and Dr. Craig Foster, Assistant Professor of uIC’s Civil & Materials Engineering Department. Additional projects include Corneal Nerve Regeneration

and Excimer Laser Ablations; and Corneal Nerve Regeneration and Crosslinking, with Dr. Azar, Dr. Jain and Dr. de la Cruz. While at UIC, Dr. Chamon hopes “to learn from Dr. Azar how to academically address new advances and new technologies in ophthalmology,” as well as learn methods to improve teamwork in research. He also plans to secure an official agreement between uIC and the Federal university of São Paulo to establish a residency exchange program between ophthalmology departments that would begin in 2012.

Dr. Allemann trained at the Federal University of São Paulo where she earned a PhD and a Masters in Medicine in ophthalmology following her medical training, ophthalmology residency and two fellowships, one in external diseases and cornea and another in ocular ultrasound and refractive surgery. She also completed a research fellowship in 1992 under Dr. Jackson Coleman at Cornell University Medical College. Since 1998 she has acted as vice president of the American Society of Ophthalmic ultrasound, a forum for the exchange of ideas and scientific discussion of ophthalmic ultrasound system design, microimaging, experimental applications, and the clinical practice of ophthalmic ultrasonography. She is also president and former scientific director of the Brazilian Society of Ecography in Ophthalmology. She will act as president for the 2012 SIDUO Meeting (Societas Internationalis Pro Diagnostica Ultrasonica in Ophthalmologia) in December 2012 that will be held in São Paulo, Brazil.

Dr. Chamon trained at the University of São Paulo in the city of Ribeirão Preto (medical training and ophthalmology residency), and earned a PhD and Masters in Medicine in ophthalmology at the Federal University of São Paulo following a fellowship in external diseases, cornea and refractive surgery. He completed a research fellowship in 1992 at Johns Hopkins university: Dr. Walter Stark served as his preceptor. Dr. Chamon is the current Coordinator of the Scientific Committee and former secretary of the Brazilian Council of Ophthalmology. He also is a scientific referee for Investigative Ophthalmology and Visual Science and, most recently, for the British Journal of Ophthalmology. He serves on the editorial board of the Journal of Refractive Surgery, and is editor-in-chief of the Brazilian Archives of Ophthalmology.

“Dr. Chamon and Dr. Allemann will contribute significantly to our research and clinical programs,” Dr. Azar states. “To continue as a top-ranked ophthalmology department we must continually renew our thinking and programs. The contributions of international leaders like Drs. Allemann and Chamon are critical to this process.”

INterNatIoNal coNtrIBUtIoNs

two Brazilian professors join the research faculty

Dr. Norma Allemann Dr. Wallace Chamon

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Margaret Doyle, Editor

Lisa Birmingham, Designer

Contributors: Margaret Chervinko • Julie Daraska • Marcia Niec • Anna Castro-Malek • Laurie Walker

Photography: Lisa Birmingham • Cathy Carroll • Joshua Clark • Roberta Dupuis-Devlin • Mark Janowicz

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