3-D Bio-Printed Prosthetics

By-Lovnish Thakur

IntroductionA prosthesis is a functional replacement for an

amputated or congenitally malformed or missing limb

Printed by a 3-D Printer using Bio-Ink.

3-D Printing Tissue Engineering

Objective

Tissue or organ failure due to aging, diseases, accidents, and birth defects is a critical medical problem

3-D PRINTING ALLOWS DOCTORS AND ENGINEERS TO PARTNER & TO REBUILD BODY PART (LIMBS) FASTER .

Method 3D bioprinting systems can be-: 1) laser-based2) inkjet-based

Process

•Deposits “bioink,” droplets of living cells or biomaterials, onto a substrate according to digital instructions to reproduce human tissues or organs.•Multiple printheads can be used to deposit different cell types (organ-specific, blood vessel, muscle cells.

CELL-INK 3D Printed Miniature Ears

• COMPANIES- ORGANOVO & BIOBOTS BUILDS MACHINES CAPABLE OF PRINTING REAL HUMAN

TISSUE CELL-INK create a standard

for the 3D bioprinting industry, with their newly universal bioink which is

aimed at 3D printing: living and fully functional 3D tissue

models

Economic Feasibility & Market Potential

Year Cost of cell(500ml)

2013 225

2014 217

2015 216

Bio-printer cost COMMERCIAL AREAS

Case study-Bioprinting of Kidney

•Cost of Kidney Transplant : $ 80,000 USD • Cost for Bioprinting of Kidney : $ 280,000 USD

Takes around 10 hours to bio-print a Kidney

Strengths1. Customization &

Personalization2. Huge market potential.

3. Provides several entrepreneurial opportunities.

4.Freedom to experiment with structures and

materials

Weaknesses1. Quality of the organs printed

2. Technolgy is still in prematured state

3. Expensive.

Opportunities1. To make new software & new machinery for

developing tissue2. Active development

of biocompatible materials.

3. Customization of designs based on customer needs

Threats1. Feasibility of Use in

the Real World 2. Questions of liability

3. Ethical Concern-In wrong hands, may contribute to fake

identity, increase in crime and illegal

activities.

Application

Rebuilds skull with 3D printing technology

3D printing makes more precise Knee implants

Skin grafts

References

1. Medical Applications for 3D Printing: Current and Projected Uses(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189697/)

2. Can We Really 3-D Print Limbs for Amputees?http://www.theatlantic.com/health/archive/2013/08/can-we-really-3-d-print-

limbs-for-amputees/278987/

3. http://health.usnews.com/health-news/health-wellness/articles/2014/07/16/how-3-d-printing-will-revolutionize-prosthetics

4. http://3dprint.com/69870/cellink-bioink-3d-bioprinting/

5. http://www.pbs.org/newshour/bb/3-d-printers-put-limb-prosthetics-for-kids-in-reach/

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Thank You