Division of Gastroenterology, Hepatology and Nutrition

Division of

GASTROENTEROLOGY,HEPATOLOGY AND NUTRITION

D e p a r t m e nt of Me d i c i n eSchool o f Medic ine

1218 Scaife Hall3550 Terrace StreetPittsburgh, PA 15261 2019

ANNUAL REPORT

TABLE OF CONTENTSMessage from the Chief 1

Faculty Listing 3

Clinical Activities 7

Clinical Quality Improvements 9

Clinical Locations 11

Research and Other Scholarly Activities 15

Teaching Activities 39

Three-Year Bibliography 48

Acknowledgments 108

Department of Medicine 2019 Annual ReportDivision of Gastroenterology, Hepatology and Nutrition


The University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition enjoyed continued success in Fiscal Year 2019. Strategic goals were defined and implemented to provide for the continued growth and success of the Division. The Division continues to be ranked among the top ten “Best Hospitals for Gastroenterology & GI Surgery” (U.S. News and World Report, July 2018).

The full, average faculty complement in FY19 was 65, which includes twelve research faculty (seven full division faculty, and five adjunct faculty). We are honored to have welcomed six new faculty members in FY19: Michael Pezzone, MD, PhD (UPMC Mercy); Siobhan Proksell, MD (Inflammatory Bowel Disease [IBD] Center); Elyse Johnston, MD (IBD Center & VAPHS); Andres Duarte-Rojo, MD, DSc (Center for Liver Diseases); Alex Myint, MD (UPMC McKeesport & Center for Liver Diseases); and Anna Evans Phillips, MD, MSc (Pancreas Center). Six faculty members left the Division: Jana Al Hashash, MD, MSc (left the U.S.); George Arnold, MD (retired); Christine Lee Gulati, MD (separated); Georgios I. Papachristou, MD, PhD (to lead pancreas programs at the Ohio State University); Fadi Francis, MD (left the U.S.); and Helen B. Sysko, PhD (retired).

FY19 was a year of successful research grants, clinical advancements, and faculty recognitions. The Division raised significant new research income, including a $6.3 million PCORI grant awarded to Eva Szigethy, MD,

Division of


GASTROENTEROLOGY Fast Facts

#10among gastroenterology and GI surgery programs

in the U.S.

$7milin research funding

65academic faculty

members

Robert E. Schoen, MD, MPHChief, Division of Gastroenterology, Hepatology and NutritionProfessor of Medicine and Epidemiology

Chad J. Scott, MPMExecutive Administrator, Division of Gastroenterology, Hepatology and Nutrition

PhD, and continued implementation of two large Department of Defense grants that explore big data implications for IBD (David Binion, MD) and for pancreas disease care (David Whitcomb, MD, PhD). Dr. Binion also received the Sherman Prize, a top annual IBD research honor. The Division is proud to welcome the Sherman Award back to the University of Pittsburgh after only two years; Dr. Szigethy won this award in 2016, its inaugural year. The Division is also honored by the promotions of Naudia Jonaissant, MD, MHS, to the position of Vice Chair for Diversity and Inclusion with the Department of Medicine and Dr. Szigethy to her new role as the director of Behavioral Health with the Chief Medical and Scientific Office at UPMC.

1


The University of Pittsburgh Division of Gastroenterology, Hepatology and Nutrition enjoyed continued success in Fiscal Year 2019. Strategic goals were defined and implemented to provide for the continued growth and success of the Division. The Division continues to be ranked among the top ten “Best Hospitals for Gastroenterology & GI Surgery” (U.S. News and World Report, July 2018).

The full, average faculty complement in FY19 was 65, which includes twelve research faculty (seven full division faculty, and five adjunct faculty). We are honored to have welcomed six new faculty members in FY19: Michael Pezzone, MD, PhD (UPMC Mercy); Siobhan Proksell, MD (Inflammatory Bowel Disease [IBD] Center); Elyse Johnston, MD (IBD Center & VAPHS); Andres Duarte-Rojo, MD, DSc (Center for Liver Diseases); Alex Myint, MD (UPMC McKeesport & Center for Liver Diseases); and Anna Evans Phillips, MD, MSc (Pancreas Center). Six faculty members left the Division: Jana Al Hashash, MD, MSc (left the U.S.); George Arnold, MD (retired); Christine Lee Gulati, MD (separated); Georgios I. Papachristou, MD, PhD (to lead pancreas programs at the Ohio State University); Fadi Francis, MD (left the U.S.); and Helen B. Sysko, PhD (retired).

FY19 was a year of successful research grants, clinical advancements, and faculty recognitions. The Division raised significant new research income, including a $6.3 million PCORI grant awarded to Eva Szigethy, MD,

Division of

GASTROENTEROLOGY, HEPATOLOGY AND NUTRITION

GASTROENTEROLOGY Fast Facts

#10among gastroenterology and GI surgery programs

in the U.S.

$7milin research funding

65academic faculty

members

Robert E. Schoen, MD, MPHChief, Division of Gastroenterology, Hepatology and NutritionProfessor of Medicine and Epidemiology

Chad J. Scott, MPMExecutive Administrator, Division of Gastroenterology, Hepatology and Nutrition

PhD, and continued implementation of two large Department of Defense grants that explore big data implications for IBD (David Binion, MD) and for pancreas disease care (David Whitcomb, MD, PhD). Dr. Binion also received the Sherman Prize, a top annual IBD research honor. The Division is proud to welcome the Sherman Award back to the University of Pittsburgh after only two years; Dr. Szigethy won this award in 2016, its inaugural year. The Division is also honored by the promotions of Naudia Jonaissant, MD, MHS, to the position of Vice Chair for Diversity and Inclusion with the Department of Medicine and Dr. Szigethy to her new role as the director of Behavioral Health with the Chief Medical and Scientific Office at UPMC.

2



FACULTYRobert E. Schoen, MD, MPHChief, Division of Gastroenterology, Hepatology and NutritionProfessor of Medicine and Epidemiology

Steven R. Abo, MDAssistant Professor of MedicineDirector, Center for Womens' GI Health

Kathryn M. Albers, PhDProfessor of Neurobiology and Medicine (Adjunt)

Jana G. Al Hashash, MD, MSc*Assistant Professor of Medicine

George L. Arnold, MD*Clinical Professor of Medicine

Gavin E. Arteel, PhDProfessor of MedicineAssociate Chief for Basic SciencePilot and Feasibility Core Director, Pittsburgh Liver Research Center

Arthur M. Barrie III, MD, PhDAssistant Professor of Medicine

Ramon Bataller Alberola, MD, PhDProfessor of MedicineChief of Hepatology

Jaideep Behari, MD, PhDAssociate Professor of Medicine

Juliane I. Beier, PhDAssistant Professor of Medicine

David G. Binion, MDProfessor of MedicineCo-Director, IBD Center - Translational ResearchDirector, Nutrition Support Service

Randall E. Brand, MDProfessor of MedicineAcademic Director, GI-Division, UPMC ShadysideDirector, GI Malignancy Early Detection, Diagnosis & Prevention Program

Rhonda M. Brand, PhDVisiting Associate Professor of Medicine

Jennifer S. Chennat, MDAssociate Professor of MedicineDirector of Therapeutic EndoscopyDirector of Interventional Endoscopy FellowshipCo-Director of Endoscopic Ultrasound Program, Liver-Pancreas Institute

Kapil B. Chopra, MDProfessor of Medicine and Clinical & Translational ScienceVice Chair of Medicine, UPMC MercyMedical Director, Comprehensive Liver Program, UPMC Liver Pancreas InstitutePrimary Physician, UPMC Liver Transplant Program, UNOS

Rohit Das, MDAssistant Professor of Medicine

Brian M. Davis, PhDProfessor of Neurobiology and Medicine (Adjunct)

Andres Duarte-Rojo, MD, MS, DScAssociate Professor of Medicine

Howard Dubner, MDClinical Associate Professor of Medicine

Mohannad Dugum, MDInstructor of Medicine

Richard H. Duerr, MDProfessor of Medicine, Human Genetics, and Clinical & Translational ScienceInflammatory Bowel Disease Genetic Research ChairCo-Director and Scientific Director, UPMC Inflammatory Bowel Disease Center

Michael A. Dunn, MDProfessor of Medicine and Biomedical InformaticsAssociate Chief for Translational Research

Kenneth E. Fasanella, MDAssistant Professor of MedicineProgram Director, Gastroenterology Fellowship

Alison J. Faust, MD, MHSAssistant Professor of Medicine

Fadi F. Francis, MD*Assistant Professor of Medicine

Swaytha R. Ganesh, MDAssistant Professor of MedicineMedical Director of Living Donor Program- UPMC Thomas E Starzl Transplant Institute

Michael S. Gold, PhDProfessor of Anesthesiology and Medicine (Adjunct)

Julia B. Greer, MD, MPHAssistant Professor of Medicine

Christine L. Gulati, MD*Clinical Assistant Professor of Medicine

Janet R. Harrison, MDAssistant Professor of Medicine

Elyse R. Johnston, MDClinical Instructor of Medicine

Naudia L. Jonassaint, MD, MHSAssistant Professor of MedicineVice Chair for Diversity and Inclusion, Department of Medicine

Asif Khalid, MDAssociate Professor of MedicineChief, GI Services, VA Pittsburgh Healthcare System

Michael J. Kingsley, MDClinical Assistant Professor of Medicine

David J. Levinthal, MD, PhDAssistant Professor of MedicineDirector, Neurogastroenterology & Motility Center

3



FACULTYRobert E. Schoen, MD, MPHChief, Division of Gastroenterology, Hepatology and NutritionProfessor of Medicine and Epidemiology

Steven R. Abo, MDAssistant Professor of MedicineDirector, Center for Womens' GI Health

Kathryn M. Albers, PhDProfessor of Neurobiology and Medicine (Adjunt)

Jana G. Al Hashash, MD, MSc*Assistant Professor of Medicine

George L. Arnold, MD*Clinical Professor of Medicine

Gavin E. Arteel, PhDProfessor of MedicineAssociate Chief for Basic SciencePilot and Feasibility Core Director, Pittsburgh Liver Research Center

Arthur M. Barrie III, MD, PhDAssistant Professor of Medicine

Ramon Bataller Alberola, MD, PhDProfessor of MedicineChief of Hepatology

Jaideep Behari, MD, PhDAssociate Professor of Medicine

Juliane I. Beier, PhDAssistant Professor of Medicine

David G. Binion, MDProfessor of MedicineCo-Director, IBD Center - Translational ResearchDirector, Nutrition Support Service

Randall E. Brand, MDProfessor of MedicineAcademic Director, GI-Division, UPMC ShadysideDirector, GI Malignancy Early Detection, Diagnosis & Prevention Program

Rhonda M. Brand, PhDVisiting Associate Professor of Medicine

Jennifer S. Chennat, MDAssociate Professor of MedicineDirector of Therapeutic EndoscopyDirector of Interventional Endoscopy FellowshipCo-Director of Endoscopic Ultrasound Program, Liver-Pancreas Institute

Kapil B. Chopra, MDProfessor of Medicine and Clinical & Translational ScienceVice Chair of Medicine, UPMC MercyMedical Director, Comprehensive Liver Program, UPMC Liver Pancreas InstitutePrimary Physician, UPMC Liver Transplant Program, UNOS

Rohit Das, MDAssistant Professor of Medicine

Brian M. Davis, PhDProfessor of Neurobiology and Medicine (Adjunct)

Andres Duarte-Rojo, MD, MS, DScAssociate Professor of Medicine

Howard Dubner, MDClinical Associate Professor of Medicine

Mohannad Dugum, MDInstructor of Medicine

Richard H. Duerr, MDProfessor of Medicine, Human Genetics, and Clinical & Translational ScienceInflammatory Bowel Disease Genetic Research ChairCo-Director and Scientific Director, UPMC Inflammatory Bowel Disease Center

Michael A. Dunn, MDProfessor of Medicine and Biomedical InformaticsAssociate Chief for Translational Research

Kenneth E. Fasanella, MDAssistant Professor of MedicineProgram Director, Gastroenterology Fellowship

Alison J. Faust, MD, MHSAssistant Professor of Medicine

Fadi F. Francis, MD*Assistant Professor of Medicine

Swaytha R. Ganesh, MDAssistant Professor of MedicineMedical Director of Living Donor Program- UPMC Thomas E Starzl Transplant Institute

Michael S. Gold, PhDProfessor of Anesthesiology and Medicine (Adjunct)

Julia B. Greer, MD, MPHAssistant Professor of Medicine

Christine L. Gulati, MD*Clinical Assistant Professor of Medicine

Janet R. Harrison, MDAssistant Professor of Medicine

Elyse R. Johnston, MDClinical Instructor of Medicine

Naudia L. Jonassaint, MD, MHSAssistant Professor of MedicineVice Chair for Diversity and Inclusion, Department of Medicine

Asif Khalid, MDAssociate Professor of MedicineChief, GI Services, VA Pittsburgh Healthcare System

Michael J. Kingsley, MDClinical Assistant Professor of Medicine

David J. Levinthal, MD, PhDAssistant Professor of MedicineDirector, Neurogastroenterology & Motility Center

4



Yang Liu, PhDAssociate Professor of Medicine and BioengineeringDirector, Biomedical Optical Imaging LaboratoryMember, University of Pittsburgh Cancer Institute Core faculty member, Department of Biomedical Informatics

Hongqiang Ma, PhDResearch Assistant Professor of Medicine

Shahid M. Malik, MDClinical Assistant Professor of MedicineAssociate Program Director, Transplant Hepatology FellowshipCo-Director, Liver Outreach Program

James B. McGee, MDAssociate Professor of MedicineAssistant Dean for Medical Education TechnologyDirector, Laboratory for Educational Technology

Kevin McGrath, MDProfessor of MedicineDirector, Endoscopic UltrasoundDirector, GI Endoscopy Lab

Satdarshan (Paul) Singh Monga, MDProfessor of Pathology and Medicine (Adjunct)Endowed Chair for Experimental PAthologyVice Chair and Chief, Division of Experimental PathologyAssistant Dean & Co-Director, Medical Scientist Training ProgramDirector, Pittsburgh Liver Research CenterDirector, Cellular Approaches to Tissue Engineering & Regeneration (CATER) Program

David Mulock, MDClinical Assistant Professor of Medicine

Alex H. Myint, MDClinical Assistant Professor of Medicine

Sudhir K. Narla, MDClinical Assistant Professor of MedicineChief, Division of Gastroenterology, UPMC McKeesport HospitalDirector, Center for Digestive Disorders, UPMC McKeesport Hospital

Stephen J.D. O'Keefe, MBBS, MD, MScProfessor of Medicine

Georgios I. Papachristou, MD, PhD*Professor of Medicine

Michael A. Pezzone, MD, PhDVisiting Associate Professor of Medicine

Anna Evans Phillips, MD, MScAssistant Professor of Medicine

Siobhan Proksell, MDAssistant Professor of Medicine

Joseph Pusateri, MDClinical Assistant Professor of Medicine

Mordechai Rabinovitz, MDProfessor of Medicine

Vikrant P. Rachakonda, MDAssistant Professor of Medicine

Shari S. Rogal, MD, MPHJohn J. Fung Assistant Professor of Transplant SurgeryAssistant Professor of Medicine (Adjunct)Core Faculty, Center for Health Equity Research and PromotionStaff Physician, VA Pittsburgh Healthcare System

Savreet Sarkaria, MDClinical Associate Professor of Medicine

Marc B. Schwartz, MDAssistant Professor of Medicine

Obaid S. Shaikh, MDProfessor of MedicineDirector, Transplantation Medicine, VA Pittsburgh Healthcare System

Harkirat Singh, MDInstructor of Medicine

Adam Slivka, MD, PhDProfessor of MedicineAssociate Chief of Clinical Affairs, Division of Gastroenterology, Hepatology and NutritionAssociate Director, Liver Pancreas Institute

Helen B. Sysko, PhD*Psychologist, Visceral Inflammation & Pain (VIP) Center

Eva M. Szigethy, MD, PhDProfessor of Medicine, Psychiatry, and PediatricsDirector, Behavioral Health with the Chief Medical and Scientific OfficeFounder, Visceral Inflammation & Pain (VIP) CenterDirector, Total Care-IBD

Dan Trellis, MDClinical Assistant Professor of Medicine

Lee Weinberg, MDClinical Assistant Professor of Medicine

David C. Whitcomb, MD, PhDProfessor of Medicine, Cell Biology & Physiology, and Human GeneticsGiant Eagle Foundation Professor of Cancer GeneticsDirector, UPMC Precision Medicine Service

John Wood, MDClinical Assistant Professor of Medicine

Kirk L. Works, MDClinical Assistant Professor of Medicine

Jianquan Xu, PhDResearch Assistant Professor of Medicine

Dhiraj Yadav, MD, MPHProfessor of Medicine

* Faculty who left the division over the course of FY 2019.

5



Yang Liu, PhDAssociate Professor of Medicine and BioengineeringDirector, Biomedical Optical Imaging LaboratoryMember, University of Pittsburgh Cancer Institute Core faculty member, Department of Biomedical Informatics

Hongqiang Ma, PhDResearch Assistant Professor of Medicine

Shahid M. Malik, MDClinical Assistant Professor of MedicineAssociate Program Director, Transplant Hepatology FellowshipCo-Director, Liver Outreach Program

James B. McGee, MDAssociate Professor of MedicineAssistant Dean for Medical Education TechnologyDirector, Laboratory for Educational Technology

Kevin McGrath, MDProfessor of MedicineDirector, Endoscopic UltrasoundDirector, GI Endoscopy Lab

Satdarshan (Paul) Singh Monga, MDProfessor of Pathology and Medicine (Adjunct)Endowed Chair for Experimental PAthologyVice Chair and Chief, Division of Experimental PathologyAssistant Dean & Co-Director, Medical Scientist Training ProgramDirector, Pittsburgh Liver Research CenterDirector, Cellular Approaches to Tissue Engineering & Regeneration (CATER) Program

David Mulock, MDClinical Assistant Professor of Medicine

Alex H. Myint, MDClinical Assistant Professor of Medicine

Sudhir K. Narla, MDClinical Assistant Professor of MedicineChief, Division of Gastroenterology, UPMC McKeesport HospitalDirector, Center for Digestive Disorders, UPMC McKeesport Hospital

Stephen J.D. O'Keefe, MBBS, MD, MScProfessor of Medicine

Georgios I. Papachristou, MD, PhD*Professor of Medicine

Michael A. Pezzone, MD, PhDVisiting Associate Professor of Medicine

Anna Evans Phillips, MD, MScAssistant Professor of Medicine

Siobhan Proksell, MDAssistant Professor of Medicine

Joseph Pusateri, MDClinical Assistant Professor of Medicine

Mordechai Rabinovitz, MDProfessor of Medicine

Vikrant P. Rachakonda, MDAssistant Professor of Medicine

Shari S. Rogal, MD, MPHJohn J. Fung Assistant Professor of Transplant SurgeryAssistant Professor of Medicine (Adjunct)Core Faculty, Center for Health Equity Research and PromotionStaff Physician, VA Pittsburgh Healthcare System

Savreet Sarkaria, MDClinical Associate Professor of Medicine

Marc B. Schwartz, MDAssistant Professor of Medicine

Obaid S. Shaikh, MDProfessor of MedicineDirector, Transplantation Medicine, VA Pittsburgh Healthcare System

Harkirat Singh, MDInstructor of Medicine

Adam Slivka, MD, PhDProfessor of MedicineAssociate Chief of Clinical Affairs, Division of Gastroenterology, Hepatology and NutritionAssociate Director, Liver Pancreas Institute

Helen B. Sysko, PhD*Psychologist, Visceral Inflammation & Pain (VIP) Center

Eva M. Szigethy, MD, PhDProfessor of Medicine, Psychiatry, and PediatricsDirector, Behavioral Health with the Chief Medical and Scientific OfficeFounder, Visceral Inflammation & Pain (VIP) CenterDirector, Total Care-IBD

Dan Trellis, MDClinical Assistant Professor of Medicine

Lee Weinberg, MDClinical Assistant Professor of Medicine

David C. Whitcomb, MD, PhDProfessor of Medicine, Cell Biology & Physiology, and Human GeneticsGiant Eagle Foundation Professor of Cancer GeneticsDirector, UPMC Precision Medicine Service

John Wood, MDClinical Assistant Professor of Medicine

Kirk L. Works, MDClinical Assistant Professor of Medicine

Jianquan Xu, PhDResearch Assistant Professor of Medicine

Dhiraj Yadav, MD, MPHProfessor of Medicine


6



CLINICAL ACTIVITIES

The Digestive Disorders Center (DDC), located in UPMC Presbyterian, is the hub of outpatient gastroenterology care, while the Center for Liver Disease (CLD) in the Starzl Transplantation Center is the outpatient clinic for liver disease care. Thedivision also sees patients at other satellite facilities including UPMC Shadyside, Magee Womens Hospital of UPMC, UPMC St. Margaret’s, UPMC Mercy, UPMC McKeesport, UPMC Passavant, UPMC Horizon, and UPMC South Hills. Three of these locations moved to enhanced office space in FY19: St. Margaret’s, Mercy, and Alison Faust, MD, MHS’s office near UPMC Horizon. Patient volume for the Division’s GI Lab, outpatient clinics, and inpatient service in FY19 are reflected in Figures 1, 2, and 3. respectively.

The Division excels in clinical care among all aspects of gastrointestinal and hepatology patient care. Its Pancreas & Biliary Center and Inflammatory Bowel Disease Center are among the largest GI clinical subspecialty care teams operating in the nation. The research and clinical productivity from these two GI subspecialty areas provide outstanding support and notoriety for the division and department. Additionally, Center for Liver Diseases collaborations with the Thomas E. Starzl Transplantation Institute, Pittsburgh Liver Research Center, and Liver Pancreas Institute have continued to expand and stabilize during the past fiscal year. The Women’s Center for Digestive Health at Magee Womens Hospital of UPMC includes full outpatient evaluations, inpatient consultations, and clinical research protocols and is a Division hub for biomedical infusions. The Division’s presence in the VA Pittsburgh Health System remains well staffed and

progressive with active research and clinical support.

Over the past year, the Division established a clinical office at UPMC Mercy. Kapil Chopra, MD, left Oakland to treat hepatology patients at UPMC Mercy, where he also serves as the hospital’s vice chair of Medicine. Michael Pezzone, MD, PhD, was recruited back to Pittsburgh and to UPMC to care for general gastroenterology patients and to serve as the chief of GI for UPMC Mercy.

IN FY19, UPMCled the nat ion with

l iver t ransplants& was the ONLY

center to perform more l i v ing-donor t ransplants

than deceased-donor

Clinical productivity was augmented by the following major clinical advancements in FY19:• In FY19, the UPMC GI Lab at UPMC Presbyterian became the first location to experience the first

human use of a disposable duodenoscope through the EXACT study. • In 2015, the UPMC Division of Gastroenterology and UPMC Health Plan partnered to establish the

UPMC Total Care-IBD specialty medical home to address the needs of patients with Inflammatory Bowel Disease (IBD). In FY19, the Total Care-IBD pilot contract was extended. Total Care-IBD represents a new model of integrated care delivery designed to address the medical, behavioral, and socioeconomic determinants of health. Also in FY19, patients who participated in Total Care-IBD had a decrease in opioid use and an improvement in quality of life and depression. 69.2% of patients who were taking opioids at their initial medical home visit discontinued opioid use within twelve months of enrolling the program. With the advent of Dr. Eva Szigethy’s $6.3 million PCORI grant, Total Care-IBD continues to provide unique and effective patient care, complemented by new telemedicine-types of counseling applications.

• In FY19, the Division’s Visceral Inflammation & Pain (VIP) Center was closed and a new medical home model for Functional GI Disorders (FGIDs) at UPMC Mercy was established in collaboration with David Levinthal, MD, PhD. Patients from the VIP center will be incorporated into the new unit.

• Dr. Levinthal is continuing to build a national reputation for Cyclic Vomiting Syndrome (CVS) care at UPMC, having published clinical guidelines for CVS care in Neurogastroenterology and Motility in FY19.

• Swaytha Ganesh, MD, leads Living Donor Liver Transplant (LDLT) referral efforts and manages this high-profile UPMC initiative in collaboration with surgical partners. In FY19, UPMC led the nation with 68 (adult and pediatric) living-donor liver transplants and was the only center to perform more living-donor liver transplants than deceased-donor liver transplants for the past two years. In collaboration with the UPMC Center for Liver Diseases, the UPMC Liver Transplant Program remains committed to ending waiting list deaths by increasing access to living donation through a national educational initiative targeted to patients, caregivers, and health providers.

• Led by Jaideep Behari, MD, PhD, the UPMC Fatty Liver, Obesity, and Wellness (FLOW) Clinic provides multidisciplinary, comprehensive, state-of-the-art care using a combination of dietary and medical approaches to treat patients with nonalcoholic fatty liver disease, obesity and the metabolic syndrome. In FY19, the FLOW clinic offered patients free, noninvasive assessment of liver

living-donor68

7



CLINICAL ACTIVITIES

The Digestive Disorders Center (DDC), located in UPMC Presbyterian, is the hub of outpatient gastroenterology care, while the Center for Liver Disease (CLD) in the Starzl Transplantation Center is the outpatient clinic for liver disease care. The division also sees patients at other satellite facilities including UPMC Shadyside, Magee Womens Hospital of UPMC, UPMC St. Margaret’s, UPMC Mercy, UPMC McKeesport, UPMC Passavant, UPMC Horizon, and UPMC South Hills. Three of these locations moved to enhanced office space in FY19: St. Margaret’s, Mercy, and Alison Faust, MD, MHS’s office near UPMC Horizon. Patient volume for the Division’s GI Lab, outpatient clinics, and inpatient service in FY19 are reflected in Figures 1, 2, and 3. respectively.

The Division excels in clinical care among all aspects of gastrointestinal and hepatology patient care. Its Pancreas & Biliary Center and Inflammatory Bowel Disease Center are among the largest GI clinical subspecialty care teams operating in the nation. The research and clinical productivity from these two GI subspecialty areas provide outstanding support and notoriety for the division and department. Additionally, Center for Liver Diseases collaborations with the Thomas E. Starzl Transplantation Institute, Pittsburgh Liver Research Center, and Liver Pancreas Institute have continued to expand and stabilize during the past fiscal year. The Women’s Center for Digestive Health at Magee Womens Hospital of UPMC includes full outpatient evaluations, inpatient consultations, and clinical research protocols and is a Division hub for biomedical infusions. The Division’s presence in the VA Pittsburgh Health System remains well staffed and

progressive with active research and clinical support.

Over the past year, the Division established a clinical office at UPMC Mercy. Kapil Chopra, MD, left Oakland to treat hepatology patients at UPMC Mercy, where he also serves as the hospital’s vice chair of Medicine. Michael Pezzone, MD, PhD, was recruited back to Pittsburgh and to UPMC to care for general gastroenterology patients and to serve as the chief of GI for UPMC Mercy.

IN FY19, UPMCled the nat ion with

l iver transplants& was the ONLY

center to perform morel i v ing-donor t ransplants

than deceased-donor

Clinical productivity was augmented by the following major clinical advancements in FY19: • In FY19, the UPMC GI Lab at UPMC Presbyterian became the first location to experience the first

human use of a disposable duodenoscope through the EXACT study.• In 2015, the UPMC Division of Gastroenterology and UPMC Health Plan partnered to establish the

UPMC Total Care-IBD specialty medical home to address the needs of patients with InflammatoryBowel Disease (IBD). In FY19, the Total Care-IBD pilot contract was extended. Total Care-IBDrepresents a new model of integrated care delivery designed to address the medical, behavioral, andsocioeconomic determinants of health. Also in FY19, patients who participated in Total Care-IBDhad a decrease in opioid use and an improvement in quality of life and depression. 69.2% of patientswho were taking opioids at their initial medical home visit discontinued opioid use within twelvemonths of enrolling the program. With the advent of Dr. Eva Szigethy’s $6.3 million PCORIgrant, Total Care-IBD continues to provide unique and effective patient care, complemented by newtelemedicine-types of counseling applications.

• In FY19, the Division’s Visceral Inflammation & Pain (VIP) Center was closed and a newmedical home model for Functional GI Disorders (FGIDs) at UPMC Mercy was established incollaboration with David Levinthal, MD, PhD. Patients from the VIP center will be incorporated intothe new unit.

• Dr. Levinthal is continuing to build a national reputation for Cyclic Vomiting Syndrome (CVS) care atUPMC, having published clinical guidelines for CVS care in Neurogastroenterology and Motility inFY19.

• Swaytha Ganesh, MD, leads Living Donor Liver Transplant (LDLT) referral efforts and manages thishigh-profile UPMC initiative in collaboration with surgical partners. In FY19, UPMC led the nation with68 (adult and pediatric) living-donor liver transplants and was the only center to perform more living-donor liver transplants than deceased-donor liver transplants for the past two years. In collaborationwith the UPMC Center for Liver Diseases, the UPMC Liver Transplant Program remains committed toending waiting list deaths by increasing access to living donation through a national educationalinitiative targeted to patients, caregivers, and health providers.

• Led by Jaideep Behari, MD, PhD, the UPMC Fatty Liver, Obesity, and Wellness (FLOW)Clinic provides multidisciplinary, comprehensive, state-of-the-art care using a combination of dietaryand medical approaches to treat patients with nonalcoholic fatty liver disease, obesity and themetabolic syndrome. In FY19, the FLOW clinic offered patients free, noninvasive assessment of liver

living-donor68

8



fibrosis as well as access to five active clinical trials and a weight loss study.

• Dr. Behari, Dr. Levinthal, andother Division faculty membersmoved their academic officesand some clinical service to theDivision’s new TranslationalResearch Center (TRC),located in UPMC Montefiorehospital. The TRC wasdesigned to encouragecollaborative translationalresearch with the Endocrine andGeriatrics Divisions, who alsoshare this space. LyndaDzubinski, RN, is the TRCmanager. Patient visits in theTRC are rapidly increasing, and amajor renovation isin the planning stages. The TRC should evolve to becoming a major locus of translational research inthe coming years.

CLINICAL QUALITY IMPROVEMENT INITIATIVESThe safety and quality of patient care is a high priority for the division. Elyse R. Johnston, MD, leads quality improvement projects for the Division in collaboration with Naudia L. Jonassaint, MD, MHS, and Belinda Marino (administrator).

The Division’s value metrics were analyzed in FY19 for both outpatients and inpatients:Outpatients

• The Division seeks to increase Advanced Practice Provide (APP) utilization per cFTE by 25% with a capof 80% capacity. This review seeks to secure APP engagement and retention. Structured activities thatfocus on education, knowledge sharing, mentorship, and engagement will be implemented.

• Standardized clinical follow-up intervals were analyzed for the top 20 diagnoses in the Division(including cirrhosis, Crohn’s disease, ulcerative colitis, GERD, irritable bowel syndrome, hepatitis, livercysts and tumors, abnormal LFTs, portal hypertension, vascular abnormality of the liver, iron overload,and liver transplantation). Faculty reached agreement within the Division, and the use of this data isbeing explored.

Inpatients• Patient prescriptions are being reviewed to ensure that at a least one prescription will be sent to a

hospital-based pharmacy.• MEDUMO patient-based digital health tools are being implemented as a value metric project to

improve colonoscopy quality. Trackable data points include bowel preparation quality and reduction in cancellations and no-show rates. An additional objective is to improve patient satisfaction and the overall patient experience by streamlining endoscopy and colonoscopy orders to deliver real-time, automated patient instructions. This value metric project is designed to improve outpatient colonoscopy bowel preparation through the overhaul and streamlining of patient instructions and bowel preparation options. From an internal perspective, this project also involves the creation of new EPIC order sets and a partnership with MEDUMO to deliver automated digital instructions to patients.

The Division includes several faculty with pancreatic expertise. Bottom row (left to right): Yang Liu, PhD; Adam Slivka, MD, PhD; David Whitcomb, MD, PhD; Anna Evans Phillips, MD, MSc. Middle row: Rohit Das, MD; Randall E. Brand, MD; and Kevin McGrath, MD. Back row: Mordechai Rabinovitz, MD; Harkirat SIngh, MBBS; Dhiraj Yadav, MD, MPH; Kenneth E. Fasanella, MD

9



fibrosis as well as access to five active clinical trials and a weight loss study.

• Dr. Behari, Dr. Levinthal, and other Division faculty members moved their academic offices and some clinical service to the Division’s new Translational Research Center (TRC), located in UPMC Montefiore hospital. The TRC was designed to encourage collaborative translational research with the Endocrine and Geriatrics Divisions, who also share this space. Lynda Dzubinski, RN, is the TRC manager. Patient visits in the TRC are rapidly increasing, and a major renovation is in the planning stages. The TRC should evolve to becoming a major locus of translational research in the coming years.

CLINICAL QUALITY IMPROVEMENT INITIATIVESThe safety and quality of patient care is a high priority for the division. Elyse R. Johnston, MD, leads quality improvement projects for the Division in collaboration with Naudia L. Jonassaint, MD, MHS, and Belinda Marino (administrator).

The Division’s value metrics were analyzed in FY19 for both outpatients and inpatients:Outpatients

• The Division seeks to increase Advanced Practice Provide (APP) utilization per cFTE by 25% with a cap of 80% capacity. This review seeks to secure APP engagement and retention. Structured activities that focus on education, knowledge sharing, mentorship, and engagement will be implemented.

• Standardized clinical follow-up intervals were analyzed for the top 20 diagnoses in the Division (including cirrhosis, Crohn’s disease, ulcerative colitis, GERD, irritable bowel syndrome, hepatitis, liver cysts and tumors, abnormal LFTs, portal hypertension, vascular abnormality of the liver, iron overload, and liver transplantation). Faculty reached agreement within the Division, and the use of this data is being explored.

Inpatients• Patient prescriptions are being reviewed to ensure that at a least one prescription will be sent to a

hospital-based pharmacy. • MEDUMO patient-based digital health tools are being implemented as a value metric project to

improve colonoscopy quality. Trackable data points include bowel preparation quality and reduction in cancellations and no-show rates. An additional objective is to improve patient satisfaction and the overall patient experience by streamlining endoscopy and colonoscopy orders to deliver real-time, automated patient instructions. This value metric project is designed to improve outpatient colonoscopy bowel preparation through the overhaul and streamlining of patient instructions and bowel preparation options. From an internal perspective, this project also involves the creation of new EPIC order sets and a partnership with MEDUMO to deliver automated digital instructions to patients.

The Division includes several faculty with pancreatic expertise. Bottom row (left to right): Yang Liu, PhD; Adam Slivka, MD, PhD; David Whitcomb, MD, PhD; Anna Evans Phillips, MD, MSc. Middle row: Rohit Das, MD; Randall E. Brand, MD; and Kevin McGrath, MD. Back row: Mordechai Rabinovitz, MD; Harkirat SIngh, MBBS; Dhiraj Yadav, MD, MPH; Kenneth E. Fasanella, MD

10



CLINICAL LOCATIONS—Central

Digestive Disorders Center (DDC), Primary Patient Center—UPMC Presbyterian200 Lothrop Street, Third FloorPittsburgh (Oakland), PA 15213

Center for Liver Diseases (CLD), Primary Hepatalogy Patient Center—UPMC Montefiore3459 Fifth Avenue, Seenth FloorPittsburgh (Oakland), PA 15213

Visceral Inflammation and Pain CenterMedical Arts Building3708 Fifth Avenue, Suite 401Pittsburgh (Oakland), PA 15213

Division of Gastroenterology, Hepatology and Nutrition—UPMC ShadysideShadyside Medical Building5200 Centre Avenue, Suite 409Pittsburgh (Shadyside), PA 15232

Center for Women’s Digestive Health—Magee-Womens Hospital of UPMC300 Halket Street, Suite 820, Basement LevelPittsburgh (Oakland), PA 15213

11



CLINICAL LOCATIONS—Central

Digestive Disorders Center (DDC), Primary Patient Center—UPMC Presbyterian200 Lothrop Street, Third FloorPittsburgh (Oakland), PA 15213

Center for Liver Diseases (CLD), Primary Hepatalogy Patient Center—UPMC Montefiore3459 Fifth Avenue, Seenth FloorPittsburgh (Oakland), PA 15213

Visceral Inflammation and Pain CenterMedical Arts Building3708 Fifth Avenue, Suite 401Pittsburgh (Oakland), PA 15213

Division of Gastroenterology, Hepatology and Nutrition—UPMC ShadysideShadyside Medical Building5200 Centre Avenue, Suite 409Pittsburgh (Shadyside), PA 15232

Center for Women’s Digestive Health—Magee-Womens Hospital of UPMC300 Halket Street, Suite 820, Basement LevelPittsburgh (Oakland), PA 15213

12



CLINICAL LOCATIONS—Peripheral

UPMC Gastroenterology—UPMC Horizon110 North Main Street, 2nd Floor, and 125 North Main Street, Suite 102 (Kirk Works, MD)Greenville, PA 16125

Center for Liver Diseases—UPMC Passavant9100 Babcock Boulevard, Basement LevelPittsburgh, PA 15237

UPMC Gastroenterology—UPMC St. Margaret’sMedical Arts Building100 Delafield Road, Suite 307Pittsburgh (Aspinwall), PA 15215

UPMC South Hills 1300 Oxford DriveBethel Park, PA 15102

St. Clair Outpatient Hospital Building2000 Oxford Drive, Suite 680Bethel Park, PA 15102

Gastroenterology (Dr. Sudhir Narla) and Center for Liver Diseases—UPMC McKeesportPainter Building500 Hospital Way, Suite 401McKeesport, PA 15132

Gastroenterology and Center for Liver Diseases—UPMC Monroeville125 Daugherty Drive, Suite 200Monroeville, PA 15146

13



CLINICAL LOCATIONS—Peripheral

UPMC Gastroenterology—UPMC Horizon110 North Main Street, 2nd Floor, and 125 North Main Street, Suite 102 (Kirk Works, MD)Greenville, PA 16125

Center for Liver Diseases—UPMC Passavant9100 Babcock Boulevard, Basement LevelPittsburgh, PA 15237

UPMC Gastroenterology—UPMC St. Margaret’sMedical Arts Building100 Delafield Road, Suite 307Pittsburgh (Aspinwall), PA 15215

UPMC South Hills 1300 Oxford DriveBethel Park, PA 15102

St. Clair Outpatient Hospital Building2000 Oxford Drive, Suite 680Bethel Park, PA 15102

Gastroenterology (Dr. Sudhir Narla) and Center for Liver Diseases—UPMC McKeesportPainter Building500 Hospital Way, Suite 401McKeesport, PA 15132

Gastroenterology and Center for Liver Diseases—UPMC Monroeville125 Daugherty Drive, Suite 200Monroeville, PA 15146

14



RESEARCH AND OTHER SCHOLARLY ACTIVITIES

The Division is a unique blend of clinical excellence, complemented by superb translational research capacity and capability. Thematic areas include inflammatorybowel disease (IBD), pancreatic diseases, hepatitis and liver diseases, functional and pain disorders, nutrition deficits, digestive system cancer risk, endoscopic management of GI cancers, and women’s digestive health. Core scientific disciplines include epidemiology, cell biology and physiology, genetics, immunology, neurosciences, tissue regeneration, transplantation, and oncogenesis. Applied sciences include biomarker development and clinical trial outcome studies.

In FY2019, our faculty engaged in cutting-edge research. The lab of Yang Liu, PhD, has developed a highly innovative approach to visualize molecular scale structures in real time. Her team was the first to discover the dual-layered scaffolding of cell nuclei as a previously unrecognized structural support for nuclear function. Her group recently uncovered the fragmentation of chromatin folding occurring early in neoplasia, even prior to tumor formation, which has the potential to improve early detection of aggressive cancers. She is the recent recipient of a new R01 grant, titled “Three-Dimensional Nanoscale Nuclear Architecture Mapping Based Taxonomy of Precursor Lesions for Predicting Colorectal Cancer Risk.”

Ramon Bataller, MD, PhD, demonstrated to the world for the first time that cold weather climate has alink to alcoholism. This study garnered worldwide interest and was publicized in virtually every major country and by major international media including the BBC, main Canadian TV, and Fox News. Dr. Bataller’s lab also uncovered a new mechanism of alcoholic hepatitis that has the potential to lead to new therapy. He demonstrated that epigenetic mechanisms lead to fetal reprogramming and defective productionof HNF4alpha, contributing to liver failure. He has a patent on this discovery and is seeking industry collaboration to further expand on its potential promise in mitigating alcoholic hepatitis. Additionally, Dr. Bataller and fellow faculty member Gavin Arteel, PhD, further explored alcoholic liver disease advancements as co-guest editors for the Journalof Hepatology’s special issue on Alcoholic Hepatitis (Feb 2019;70(2)).

A hepatologist at the VAPHS and adjunct Division research faculty in FY19,

I n F Y 1 9 , t h e D i v i s i o n ’sr e s e a r c h e x p e n d i t u r e s

a p p r o a c h e d

$8m

30%

Shari Rogal, MD, MPH, developed and used novel implementation strategy assessments to evaluate how sites across the VA approach uptake of evidence-based practices. With novel analytics that include traditional and configurational comparative methods to show how to improve VA care, her research reaches a number of relevant domains such as HCV care, cirrhosis care, HIV, addiction care, opioid safety, and intimate partner violence initiatives. Her work has been accepted at leading implementation science meetings and journals. Dr. Rogal is also launching a University of Pittsburgh implementation science group (DISC), an interdisciplinary collaboration that crosses University schools and departments. Dr. Rogal will become a full-Division faculty in FY20.

Another faculty member, Dhiraj Yadav, MD, MPH, is co-leading three multi-institutional projects:• The PROCEED study is the first longitudinal, observational cohort study of chronic pancreatitis in the

U.S., and PROCEED is one of four cohorts that have been established by the ten-center U01 Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Primary objectives include the establishment of a longitudinal research cohort of adult subjects to study chronic pancreatitis (CP) and complications, to estimate the risk of disease progression, to test the predictive capability of candidate biomarkers for the diagnosis and prognosis of CP, and to develop a platform for conducting biomarker, genetic, and mechanistic studies using clinical information and longitudinal biospecimens. Dr. Yadav is also the site PI for two other CPDPC projects: the DETECT study, which will enroll subjects with either Type 2DM or DM related to CP or pancreatic cancer to undergo a mixed meal tolerance test with a goal to develop a clinical test to differentiate between these conditions; and MINIMAP, which will evaluate novel MRI features to predict early CP changes.

• The SpHincterotomy for Acute Recurrent Pancreatitis (SHARP) study is also funded through a U01 consortium. The 17 academic medical centers in this study will work to determine whether an ERCP with minor papilla sphincterotomy reduces the risk for pancreatitis in patients with pancreas divisum, an issue that has been debated for more than 30 years. Study results will directly impact clinical practice.

• ACCESS-AP is a case crossover study that will examine the role of short-term increases in alcohol consumption related to the risk of pancreatitis in patients who report regular drinking. Results of this five-site study will inform tailored interventions to prevent recurrence of pancreatitis and disease progression in regular drinkers. A biorepository will be established to uncover mechanisms of pancreatitis related to alcohol and smoking.

Eva Szigethy, MD, PhD, reports that chronic GI conditions have high rates of behavioral comorbidities, but cost-effective, integrated, medical-behavioral care remains challenging. She is the lead investigator on two clinical research initiatives:

• Dr. Szigethy’s $6.3 million PCORI study will be conducted within the Division’s specialty medical home, Total Care-IBD. This study will seek to identify how health technology can provide for accessible, scalable, high-quality, and integrated care for patients with chronic medical conditions like IBD. Two strategies for the delivery of integrated medical and behavioral care will be compared: 1) in-person care in the GI Clinic (TEAM); and 2) a technology-supported approach, in which care will be provided by telemedicine and digital apps primarily (TECH). She believes that outcomes may be scalable to other common chronic conditions.

• Dr. Szigethy is also investigating how patients with functional GI disorders (FGIDs) can receive more efficient screening for common psychiatric disorders such as mood and anxiety disorders, PTSD, and substance abuse disorders. She and her colleagues will use adaptive computerized testing and vocal

1 yearin just

an increase of over

15



RESEARCH AND OTHER SCHOLARLY ACTIVITIES

The Division is a unique blend of clinical excellence, complemented by superb translational research capacity and capability. Thematic areas include inflammatory bowel disease (IBD), pancreatic diseases, hepatitis and liver diseases, functional and pain disorders, nutrition deficits, digestive system cancer risk, endoscopic management of GI cancers, and women’s digestive health. Core scientific disciplines include epidemiology, cell biology and physiology, genetics, immunology, neurosciences, tissue regeneration, transplantation, and oncogenesis. Applied sciences include biomarker development and clinical trial outcome studies.

In FY2019, our faculty engaged in cutting-edge research. The lab of Yang Liu, PhD, has developed a highly innovative approach to visualize molecular scale structures in real time. Her team was the first to discover the dual-layered scaffolding of cell nuclei as a previously unrecognized structural support for nuclear function. Her group recently uncovered the fragmentation of chromatin folding occurring early in neoplasia, even prior to tumor formation, which has the potential to improve early detection of aggressive cancers. She is the recent recipient of a new R01 grant, titled “Three-Dimensional Nanoscale Nuclear Architecture Mapping Based Taxonomy of Precursor Lesions for Predicting Colorectal Cancer Risk.”

Ramon Bataller, MD, PhD, demonstrated to the world for the first time that cold weather climate has a link to alcoholism. This study garnered worldwide interest and was publicized in virtually every major country and by major international media including the BBC, main Canadian TV, and Fox News. Dr. Bataller’s lab also uncovered a new mechanism of alcoholic hepatitis that has the potential to lead to new therapy. He demonstrated that epigenetic mechanisms lead to fetal reprogramming and defective production of HNF4alpha, contributing to liver failure. He has a patent on this discovery and is seeking industry collaboration to further expand on its potential promise in mitigating alcoholic hepatitis. Additionally, Dr. Bataller and fellow faculty member Gavin Arteel, PhD, further explored alcoholic liver disease advancements as co-guest editors for the Journal of Hepatology’s special issue on Alcoholic Hepatitis (Feb 2019;70(2)).

A hepatologist at the VAPHS and adjunct Division research faculty in FY19,

I n F Y 1 9 , t h e D i v i s i o n ’sr e s e a r c h e x p e n d i t u r e s

a p p r o a c h e d

$8m

30%

Shari Rogal, MD, MPH, developed and used novel implementation strategy assessments to evaluate how sites across the VA approach uptake of evidence-based practices. With novel analytics that include traditional and configurational comparative methods to show how to improve VA care, her research reaches a number of relevant domains such as HCV care, cirrhosis care, HIV, addiction care, opioid safety, and intimate partner violence initiatives. Her work has been accepted at leading implementation science meetings and journals. Dr. Rogal is also launching a University of Pittsburgh implementation science group (DISC), an interdisciplinary collaboration that crosses University schools and departments. Dr. Rogal will become a full-Division faculty in FY20.

Another faculty member, Dhiraj Yadav, MD, MPH, is co-leading three multi-institutional projects: • The PROCEED study is the first longitudinal, observational cohort study of chronic pancreatitis in the

U.S., and PROCEED is one of four cohorts that have been established by the ten-center U01 Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Primary objectives include the establishment of a longitudinal research cohort of adult subjects to study chronic pancreatitis (CP) and complications, to estimate the risk of disease progression, to test the predictive capability of candidate biomarkers for the diagnosis and prognosis of CP, and to develop a platform for conducting biomarker, genetic, and mechanistic studies using clinical information and longitudinal biospecimens. Dr. Yadav is also the site PI for two other CPDPC projects: the DETECT study, which will enroll subjects with either Type 2DM or DM related to CP or pancreatic cancer to undergo a mixed meal tolerance test with a goal to develop a clinical test to differentiate between these conditions; and MINIMAP, which will evaluate novel MRI features to predict early CP changes.

• The SpHincterotomy for Acute Recurrent Pancreatitis (SHARP) study is also funded through a U01 consortium. The 17 academic medical centers in this study will work to determine whether an ERCP with minor papilla sphincterotomy reduces the risk for pancreatitis in patients with pancreas divisum, an issue that has been debated for more than 30 years. Study results will directly impact clinical practice.

• ACCESS-AP is a case crossover study that will examine the role of short-term increases in alcohol consumption related to the risk of pancreatitis in patients who report regular drinking. Results of this five-site study will inform tailored interventions to prevent recurrence of pancreatitis and disease progression in regular drinkers. A biorepository will be established to uncover mechanisms of pancreatitis related to alcohol and smoking.

Eva Szigethy, MD, PhD, reports that chronic GI conditions have high rates of behavioral comorbidities, but cost-effective, integrated, medical-behavioral care remains challenging. She is the lead investigator on two clinical research initiatives:

• Dr. Szigethy’s $6.3 million PCORI study will be conducted within the Division’s specialty medical home, Total Care-IBD. This study will seek to identify how health technology can provide for accessible, scalable, high-quality, and integrated care for patients with chronic medical conditions like IBD. Two strategies for the delivery of integrated medical and behavioral care will be compared: 1) in-person care in the GI Clinic (TEAM); and 2) a technology-supported approach, in which care will be provided by telemedicine and digital apps primarily (TECH). She believes that outcomes may be scalable to other common chronic conditions.

• Dr. Szigethy is also investigating how patients with functional GI disorders (FGIDs) can receive more efficient screening for common psychiatric disorders such as mood and anxiety disorders, PTSD, and substance abuse disorders. She and her colleagues will use adaptive computerized testing and vocal

1 yearin just

an increase of over

16



and visual behavior markers to identify these disorders, and she and her team will investigate the effectiveness of coach-facilitated digital behavioral tools to improve mood, behavior, and pain. This study will operate within the new Functional GI Disorders (FGIDs) medical home at the UPMC Mercy GI Outpatient Clinic.

Robert E. Schoen, MD, MPH’s efforts in early detection and prevention of CRC continue to pioneer new fronts in expanding and improving screening, implementation, and quality. He is a lead investigator on multiple clinical research initiatives:

• As a principal investigator and member of the executive committee for the National Cancer Institute’s Early Detection Research Network, Dr. Schoen is collaborating with Drs. Kenneth Kinzler and Bert Vogelstein at Johns Hopkins University to evaluate a blood test for cancer that uses circulating tumor DNA (ctDNA). Initial results were published in Science in 2018 and have generated considerable interest.

• Dr. Schoen and colleagues published multiple papers using a natural language processing tool to analyze colonoscopy and pathology reports to measure physician quality. UPMC Enterprise has now developed such a tool, and plans to implement it for use in the UPMC system are underway.

• Dr. Schoen and colleagues published a landmark study in JAMA in 2018 on the outcome of surveillance colonoscopy after adenomatous polyps are discovered. The National Cancer Institute has decided to fund a 15,000 patient randomized trial in conjunction with the NRG oncology group and the National Community Oncology Research Program (NCORP), which will be directed by Dr. Schoen.

Faculty Research Interests and ActivitiesRobert E. Schoen, MD, MPH Division ChiefDr. Schoen is a Professor of Medicine and Epidemiology and his research interests center on the early detection and prevention of colorectal cancer (CRC). He is a Principal Investigator in the PLCO cancer screening trial, a randomized trial of over 154,000 individuals that evaluated flexible sigmoidoscopy. He has used PLCO data to study surveillance colonoscopy utilization and yield, interval cancers, or cancers detected shortly after endoscopic procedures, as well as the risk of colorectal cancer among subjects with a family history of cancer. In collaboration with the Mayo Clinic in Minnesota, Dr Schoen is the Principal Investigator of a multicenter randomized immunotherapy trial, evaluating a vaccine for prevention of recurrent adenomatous polyps. He is also a Principal Investigator for the Early Detection Research Network and collaborates with scientists nationally and internationally to identify biomarkers, including circulating tumor DNA and tissue-based markers, to detect and monitor cancer. As an investigator in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Dr. Schoen is part of a consortium studying genetic and environmental risk factors for CRC, including genome-wide association studies and molecular pathologic epidemiology research and modeling of CRC risk using genetic and environmental risk factors. Lastly, he is a co-investigator in a study evaluating colonoscopy quality and is helping to develop a natural language processing tool to evaluate and report on colonoscopy quality in a more efficient manner. In conjunction with that project, Dr. Schoen is developing a database of colonoscopy reports from the last 20 years at UPMC hospital for research studies on colonoscopy.

Advisory Committee Memberships and Leadership Positions• Chair, Colon Organ Site Committee, Prostate, Lung, Colorectal & Ovarian Cancer Screening Trial,

2002-present

• Program Project Reviewer, Clinical Research Training Fellowship, Cancer Research United Kingdom, 2006-present

• President, Pittsburgh Gut Club, 2008-present• Member, National Cancer Institute Early Detection Research Network Executive Committee, 2016-

present• Chair, GI subcommittee, Early Detection Research Network, 2016-present

Editorships• Editorial Board, Clinical Gastroenterology and Hepatology, 2007-present• Reviewer, Multiple journals (New England Journal of Medicine, Gastroenterology, Clinical

Gastroenterology and Hepatology, American Journal of Gastroenterology, Journal of the National Cancer Institute, JAMA, Gut), 2007-present

Honors and Awards• Honoree, Best Doctors, Pittsburgh Magazine, 2012-present

Steven R. Abo, MDDr. Abo is an Assistant Professor whose research interests include clinical research studies pertaining to the pathogenesis and treatment of irritable bowel syndrome. He also serves as the Director for the Center for Women's GI Health.

Advisory Committee Memberships and Leadership Positions• Director, Center for Women’s Digestive Health, Magee-Women’s Hospital of UPMC, 2000-present

Jana G. Al Hashash, MD, MSc*Dr. Al Hashash investigates aberrant MUC1 expression in Crohn's disease patients. She works in conjunction with Olivera Finn, PhD, from the Department of Immunology. Together, they plan to conduct a vaccine trial by giving MUC1 vaccine to Crohn's disease patients in the postoperative setting to prevent the recurrence of their Crohn's disease. In addition, Dr. Al Hashash is collaborating with Yang Liu, PhD, on research to detect early colonic dysplasia and colon cancer in high-risk IBD patients via noninvasive biomarkers.

Professional Affiliations and Society Memberships• Member, American Society for Gastrointestinal Endoscopy, 2010-present• Member, American Gastroenterological Association, 2011-present• Member, American College of Gastroenterology, 2011-present• Physician Member, Crohn's and Colitis Foundation of America (CCFA), 2012-present

Editorships• Peer Reviewer, Inflammatory Bowel Disease Journal, 2012-present• Peer Reviewer, Clinical Gastroenterology and Hepatology, 2012-present• Peer Reviewer, Cleveland Clinic Journal of Medicine, 2012-present• Peer Reviewer, Alimentary Pharmacology and Therapeutics, 2012-present• Peer Reviewer, ACG Case Report Journal, 2013-present

Kathryn M. Albers, PhDDr. Albers is a Professor of Neurobiology and Medicine whose research interests are focused on tissue-derived neurotrophic growth factors that regulate sensory neuron development, their functional properties, and changes in excitability that occur following nerve injury and disease. Dr. Albers has an additional project

17



and visual behavior markers to identify these disorders, and she and her team will investigate the effectiveness of coach-facilitated digital behavioral tools to improve mood, behavior, and pain. This study will operate within the new Functional GI Disorders (FGIDs) medical home at the UPMC Mercy GI Outpatient Clinic.

Robert E. Schoen, MD, MPH’s efforts in early detection and prevention of CRC continue to pioneer new fronts in expanding and improving screening, implementation, and quality. He is a lead investigator on multiple clinical research initiatives:

• As a principal investigator and member of the executive committee for the National Cancer Institute’s Early Detection Research Network, Dr. Schoen is collaborating with Drs. Kenneth Kinzler and Bert Vogelstein at Johns Hopkins University to evaluate a blood test for cancer that uses circulating tumor DNA (ctDNA). Initial results were published in Science in 2018 and have generated considerable interest.

• Dr. Schoen and colleagues published multiple papers using a natural language processing tool to analyze colonoscopy and pathology reports to measure physician quality. UPMC Enterprise has now developed such a tool, and plans to implement it for use in the UPMC system are underway.

• Dr. Schoen and colleagues published a landmark study in JAMA in 2018 on the outcome of surveillance colonoscopy after adenomatous polyps are discovered. The National Cancer Institute has decided to fund a 15,000 patient randomized trial in conjunction with the NRG oncology group and the National Community Oncology Research Program (NCORP), which will be directed by Dr. Schoen.

Faculty Research Interests and ActivitiesRobert E. Schoen, MD, MPH Division ChiefDr. Schoen is a Professor of Medicine and Epidemiology and his research interests center on the early detection and prevention of colorectal cancer (CRC). He is a Principal Investigator in the PLCO cancer screening trial, a randomized trial of over 154,000 individuals that evaluated flexible sigmoidoscopy. He has used PLCO data to study surveillance colonoscopy utilization and yield, interval cancers, or cancers detected shortly after endoscopic procedures, as well as the risk of colorectal cancer among subjects with a family history of cancer. In collaboration with the Mayo Clinic in Minnesota, Dr Schoen is the Principal Investigator of a multicenter randomized immunotherapy trial, evaluating a vaccine for prevention of recurrent adenomatous polyps. He is also a Principal Investigator for the Early Detection Research Network and collaborates with scientists nationally and internationally to identify biomarkers, including circulating tumor DNA and tissue-based markers, to detect and monitor cancer. As an investigator in the Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Dr. Schoen is part of a consortium studying genetic and environmental risk factors for CRC, including genome-wide association studies and molecular pathologic epidemiology research and modeling of CRC risk using genetic and environmental risk factors. Lastly, he is a co-investigator in a study evaluating colonoscopy quality and is helping to develop a natural language processing tool to evaluate and report on colonoscopy quality in a more efficient manner. In conjunction with that project, Dr. Schoen is developing a database of colonoscopy reports from the last 20 years at UPMC hospital for research studies on colonoscopy.

Advisory Committee Memberships and Leadership Positions• Chair, Colon Organ Site Committee, Prostate, Lung, Colorectal & Ovarian Cancer Screening Trial,

2002-present

• Program Project Reviewer, Clinical Research Training Fellowship, Cancer Research United Kingdom, 2006-present

• President, Pittsburgh Gut Club, 2008-present• Member, National Cancer Institute Early Detection Research Network Executive Committee, 2016-

present• Chair, GI subcommittee, Early Detection Research Network, 2016-present

Editorships• Editorial Board, Clinical Gastroenterology and Hepatology, 2007-present• Reviewer, Multiple journals (New England Journal of Medicine, Gastroenterology, Clinical

Gastroenterology and Hepatology, American Journal of Gastroenterology, Journal of the National Cancer Institute, JAMA, Gut), 2007-present


Steven R. Abo, MDDr. Abo is an Assistant Professor whose research interests include clinical research studies pertaining to the pathogenesis and treatment of irritable bowel syndrome. He also serves as the Director for the Center for Women's GI Health.

Advisory Committee Memberships and Leadership Positions• Director, Center for Women’s Digestive Health, Magee-Women’s Hospital of UPMC, 2000-present

Jana G. Al Hashash, MD, MSc*Dr. Al Hashash investigates aberrant MUC1 expression in Crohn's disease patients. She works in conjunction with Olivera Finn, PhD, from the Department of Immunology. Together, they plan to conduct a vaccine trial by giving MUC1 vaccine to Crohn's disease patients in the postoperative setting to prevent the recurrence of their Crohn's disease. In addition, Dr. Al Hashash is collaborating with Yang Liu, PhD, on research to detect early colonic dysplasia and colon cancer in high-risk IBD patients via noninvasive biomarkers.

Professional Affiliations and Society Memberships• Member, American Society for Gastrointestinal Endoscopy, 2010-present• Member, American Gastroenterological Association, 2011-present• Member, American College of Gastroenterology, 2011-present• Physician Member, Crohn's and Colitis Foundation of America (CCFA), 2012-present

Editorships• Peer Reviewer, Inflammatory Bowel Disease Journal, 2012-present• Peer Reviewer, Clinical Gastroenterology and Hepatology, 2012-present• Peer Reviewer, Cleveland Clinic Journal of Medicine, 2012-present• Peer Reviewer, Alimentary Pharmacology and Therapeutics, 2012-present• Peer Reviewer, ACG Case Report Journal, 2013-present

Kathryn M. Albers, PhDDr. Albers is a Professor of Neurobiology and Medicine whose research interests are focused on tissue-derived neurotrophic growth factors that regulate sensory neuron development, their functional properties, and changes in excitability that occur following nerve injury and disease. Dr. Albers has an additional project

18



examining the function of the transcription factor Sox11. Sox11 plays a critical role in embryonic neuron specification, growth and survival, and adult peripheral nerve regeneration.

George Arnold, MDDr. Arnold is a Clinical Professor of Medicine who has previously been involved in clinical research in inflammatory bowel disease and irritable bowel syndrome, has supervised studies in these areas, presented at national meetings, and published clinical studies.

Gavin E. Arteel, PhDDr. Arteel’s research focuses on the interaction between hepatotoxicants (e.g., arsenic) and lifestyle choices (e.g., obesity and alcohol) in the initiation and progression of chronic liver diseases. His current research foci are based on the understanding that transitional changes to the ECM proteome (i.e., “matrisome”) play an underappreciated role in the initiation and progression of liver disease. He is developing computational tools to attempt to predict mechanism(s) and to develop biomarkers (or surrogate biomarkers) for use in the clinics.

Study Sections• Member, XNDA study section, 2010-2014• Chair, Hepatobiliary and Pathophysiology (HBPP) study section, 2018-present

Advisory Committee Memberships and Leadership Positions• Member and Chair, Basic Research Committee, American Association for the Study

of Liver Diseases, 2015-2017Professional Affiliations and Society Memberships

• Member, Research Society on Alcoholism, 2002-present• Member, Society of Toxicology, 2002-present• Member, American Association for the Study of Liver Diseases, 2003-present• Member, American Gastroenterological Society, 2010-present

Editorships• Editorial Board, Hepatology, 2006-present

Honors and Awards• Fellow of the American Association for the Study of Liver Diseases (FAASLD), 2015• Alumnus of the Year, Phamacology-Toxicology Program, University of Wisconsin-

Madison, 2019

Arthur M. Barrie III, MD, PhDDr. Barrie focuses on IBD patient outcomes and optimizing IBD treatment.

Advisory Committee Memberships and Leadership Positions• Medical Director, Magee Infusion Center, 2017-present

Ramon Bataller Alberola, MD, PhDAs the Chief of Hepatology, Dr. Bataller's research interests include liver fibrosis and the mechanisms and determinants of mortality of alcoholic liver disease. He has performed translational studies primarily including human samples and experimental models of liver disease. A more recent research interest of Dr. Battaler

involves his exploration of the global public health aspects of alcoholic liver disease and is the PI for an NIH-funded consortium (InTeam) for translational research of alcoholic hepatitis that seeks to identify molecular subtypes and novel targets for therapy.

Study Sections• Permanent Member, Hepatobiliary Pathophysiology Study Section, NIH, 2018-

presentAdvisory Committee Memberships and Leadership Positions

• Associate Member, UNC Lineberger Comprehensive Cancer Group, 2014-present• Member, AASLD Education Committee, 2016-present• Chief of Hepatology, UPMC, 2018-present

Professional Affiliations and Society Memberships• Member, European Association for the Study of the Liver, 2009-present• Member, American Association for the Study of Liver Disease, 2013-present• Member, Research Society of Alcoholism, 2013-present• Member, International Society in Biomedical Research in Alcoholism, 2013-present• Member, American College of Gastroenterology, 2016-present• Member, Latin American Association for the Study of the Liver, 2016-present

Editorships• Editorial Board, World Journal of Gastroenterology, 2006-present• Editorial Board, Gastroenterology Research and Practice, 2009-present• Editorial Board, Nature Reviews in Gastroenterology and Hepatology, 2012-present• Co-editor, Journal of Hepatology, 2014-present

Major Lectureships and Seminars• Invited Speaker, "Survival After Liver Transplant in Alcoholic Patients," Medical,

Surgical & Ethical Management of Alcohol-mediated Liver Disease: International Expert Opinion and Clinical Challenges, Houston, TX, 2018


Jaideep Behari, MD, PhDDr. Behari’s research investigates the role of intracellular signaling pathways in the pathogenesis of liver diseases. He is also interested in nonalcoholic fatty liver disease, alcoholic fatty liver disease and hepatocellular carcinoma.

Juliane I. Beier, PhDDr. Beier focuses on environmental vinyl chloride exposure in the context of existing underlying liver disease. Clearly high occupational exposure to vinyl chloride is directly hepatotoxic; what is less well clear is the impact of lower environmental exposure on exacerbating existing liver disease. Given the fact that a significant portion of the population has risk factors for liver disease (most commonly, obesity), and that 30% of the US population has elevated indices of liver damage, any potential impact of low environmental exposure could be dramatic. Her findings indicate that vinyl chloride will exacerbate liver damage caused by another factor. This work shifts the paradigm of current risk assessment for not only this compound, but any other environmental agent that may potentially damage the liver.

19



examining the function of the transcription factor Sox11. Sox11 plays a critical role in embryonic neuron specification, growth and survival, and adult peripheral nerve regeneration.

George Arnold, MDDr. Arnold is a Clinical Professor of Medicine who has previously been involved in clinical research in inflammatory bowel disease and irritable bowel syndrome, has supervised studies in these areas, presented at national meetings, and published clinical studies.

Gavin E. Arteel, PhDDr. Arteel’s research focuses on the interaction between hepatotoxicants (e.g., arsenic) and lifestyle choices (e.g., obesity and alcohol) in the initiation and progression of chronic liver diseases. His current research foci are based on the understanding that transitional changes to the ECM proteome (i.e., “matrisome”) play an underappreciated role in the initiation and progression of liver disease. He is developing computational tools to attempt to predict mechanism(s) and to develop biomarkers (or surrogate biomarkers) for use in the clinics.

Study Sections• Member, XNDA study section, 2010-2014• Chair, Hepatobiliary and Pathophysiology (HBPP) study section, 2018-present

Advisory Committee Memberships and Leadership Positions• Member and Chair, Basic Research Committee, American Association for the Study

of Liver Diseases, 2015-2017Professional Affiliations and Society Memberships

• Member, Research Society on Alcoholism, 2002-present• Member, Society of Toxicology, 2002-present• Member, American Association for the Study of Liver Diseases, 2003-present• Member, American Gastroenterological Society, 2010-present

Editorships• Editorial Board, Hepatology, 2006-present

Honors and Awards• Fellow of the American Association for the Study of Liver Diseases (FAASLD), 2015• Alumnus of the Year, Phamacology-Toxicology Program, University of Wisconsin-

Madison, 2019

Arthur M. Barrie III, MD, PhDDr. Barrie focuses on IBD patient outcomes and optimizing IBD treatment.

Advisory Committee Memberships and Leadership Positions• Medical Director, Magee Infusion Center, 2017-present

Ramon Bataller Alberola, MD, PhDAs the Chief of Hepatology, Dr. Bataller's research interests include liver fibrosis and the mechanisms and determinants of mortality of alcoholic liver disease. He has performed translational studies primarily including human samples and experimental models of liver disease. A more recent research interest of Dr. Battaler

involves his exploration of the global public health aspects of alcoholic liver disease and is the PI for an NIH-funded consortium (InTeam) for translational research of alcoholic hepatitis that seeks to identify molecular subtypes and novel targets for therapy.

Study Sections• Permanent Member, Hepatobiliary Pathophysiology Study Section, NIH, 2018-

presentAdvisory Committee Memberships and Leadership Positions

• Associate Member, UNC Lineberger Comprehensive Cancer Group, 2014-present• Member, AASLD Education Committee, 2016-present• Chief of Hepatology, UPMC, 2018-present

Professional Affiliations and Society Memberships• Member, European Association for the Study of the Liver, 2009-present• Member, American Association for the Study of Liver Disease, 2013-present• Member, Research Society of Alcoholism, 2013-present• Member, International Society in Biomedical Research in Alcoholism, 2013-present• Member, American College of Gastroenterology, 2016-present• Member, Latin American Association for the Study of the Liver, 2016-present

Editorships• Editorial Board, World Journal of Gastroenterology, 2006-present• Editorial Board, Gastroenterology Research and Practice, 2009-present• Editorial Board, Nature Reviews in Gastroenterology and Hepatology, 2012-present• Co-editor, Journal of Hepatology, 2014-present

Major Lectureships and Seminars• Invited Speaker, "Survival After Liver Transplant in Alcoholic Patients," Medical,

Surgical & Ethical Management of Alcohol-mediated Liver Disease: International Expert Opinion and Clinical Challenges, Houston, TX, 2018


Jaideep Behari, MD, PhDDr. Behari’s research investigates the role of intracellular signaling pathways in the pathogenesis of liver diseases. He is also interested in nonalcoholic fatty liver disease, alcoholic fatty liver disease and hepatocellular carcinoma.

Juliane I. Beier, PhDDr. Beier focuses on environmental vinyl chloride exposure in the context of existing underlying liver disease. Clearly high occupational exposure to vinyl chloride is directly hepatotoxic; what is less well clear is the impact of lower environmental exposure on exacerbating existing liver disease. Given the fact that a significant portion of the population has risk factors for liver disease (most commonly, obesity), and that 30% of the US population has elevated indices of liver damage, any potential impact of low environmental exposure could be dramatic. Her findings indicate that vinyl chloride will exacerbate liver damage caused by another factor. This work shifts the paradigm of current risk assessment for not only this compound, but any other environmental agent that may potentially damage the liver.

20



Advisory Committee Memberships and Leadership Positions• Abstract Review Board, member, American Association for the Study of Liver Diseases (AASLD),

2015-present• Abstract Review Board, member, Digestive Disease Week (DDW), 2015-present

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases (AASLD), 2007-present• Member, International Society for Hepatic Sinusoidal Research (ISHSR), 2010-present• Member, Society of Toxicology (SOT), 2013-present

Editorships• Ad Hoc Reviewer, Multiple journals (American Journal of Physiology: Gastrointestional and Liver

Physiology; Annals of Hepatology; Archives of Biochemistry and Biophysics; Hepatology; Journal of Pharmacology and Experimental Therapeutics; Journal of Hepatology; Toxicology and Applied Pharmacology; Toxicological Sciences), 2008-present

David G. Binion, MDDr. Binion is an inflammatory bowel disease (IBD) investigator whose career has focused on defining the cellular and molecular mechanisms underlying human chronic gut inflammation and translating that knowledge into improved care for patients suffering from Crohn's disease and ulcerative colitis. His current work centers on Big Data analytics and the development and transformation of the UPMC IBD Registry, a prospective, multi-year, longitudinal natural history registry database of >3,000 consented IBD patients, into a metadata platform for scientific discovery. Through a collaboration with computer scientists from the University of Pittsburgh School of Information Science, this relational database continuously curates and transforms observational clinical information from the electronic medical record (EMR) and maintains >10,000 person-years of associated metadata in a secure data warehouse. Areas of active investigation include: Developing prognostic biomarkers of IBD severity, characterizing the impact of diet and nutrition on IBD natural history, identifying biomarker patterns to predict development of dysplasia/cancer in IBD, identifying predictive biomarkers to guide therapeutic selection in IBD, comparative effectiveness studies in IBD maintenance therapy, defining the impact of surgical anastomotic technique on longterm clinical outcomes in Crohn's disease, use of healthcare charge data as a comprehensive phenotype, defining the impact of Clostridium difficile infection on IBD natural history, characterizing extra-intestinal manifestations--including anemia and autonomic dysfunction--on the natural history of IBD, developing clinical decision support tools to optimize IBD care, and implementing precision medicine.

Advisory Committee Memberships and Leadership Positions• Member, Executive Board, Crohn’s and Colitis Foundation of America, 1999-present

• Director, Translational Inflammatory Bowel Disease Research, University of Pittsburgh, 2008-present

• Co-Director, Inflammatory Bowel Disease Center, University of Pittsburgh, 2008-present• Member, Steering Committee, (SECURE) FDA Mandated Safety Registry UCB Pharma, Inc.,

2009-2019• Medical Director, GI and Nutrition Therapy (GIANT), 2013-present• Director, Nutrition Support Service, 2013-present• Member, Nutrition Subcommittee, UPMC Presbyterian-Shadyside Hospitals, 2013-present• Co-Director, Gastroenterology T32 Training Program, 2018-present

Editorships• Editorial Advisory Board, The American Journal of Gastroenterology, 2007-present• Editorial Advisory Board, World Journal of Gastroenterology, 2007-present• Editorial Advisory Board, Clinical and Translational Science, 2008-present• Editorial Advisory Board, Clinical Gastroenterology and Hepatology, 2014-present

Honors and Awards• Honoree, Best Doctors in America, 2002-present• Honoree, Pittsburgh's Best Doctors, Pittsburgh Magazine, 2014-present• Awardee, Sherman Prize, Sherman Foundation, Advances in IBD Conference, Orlando, FL,

December 2018

Randall E. Brand, MDDr. Brand is a physician-scientist with an extensive background in pancreatic diseases, and his research focuses primarily on the early diagnosis of pancreatic cancer and cystic lesions of the pancreas. He also studies familial pancreatic cancer and other hereditary GI disorders. He is leader of the University of Pittsburgh's Pancreatic Adenocarcinoma Gene-Environment Registry (PAGER). The biospecimen repository, developed as part of the PAGER study, is nationally recognized and serves as an excellent resource for multiple NIH/NC-funded projects as well as for national and international collaborations with outside researchers. Dr. Brand is a key contributor to the Early Detection Research Network, especially in research related to pancreatic cancer and cystic neoplasms. He is currently funded in the network as a principal investigator to lead both a multi-center Pancreatic Cancer Clinical Validation Center and a Biomarker Developmental Laboratory.

Advisory Committee Memberships and Leadership Positions• Director, GI Section and Academic Director, Shadyside Hospital, 2007-present• Director, GI Malignancy Early Detection, Diagnosis and Prevention Program, UPMC, 2007-present• Member, GI Fellowship Committee, University of Pittsburgh, 2007-present• Member, Pancreatic Cancer Clinical Pathways Committee, University of Pittsburgh Medical Center,

2008-present• Member, Collaborative Alliance for Pancreatic Education and Research, 2009-present• Member, Health Sciences Bridge Funding Committee, 2010-present• Chief, Therapeutic Endoscopy, Division of Gastroenterology & Hepatology, University of

Pittsburgh Medical Center, 2011-present• Member, Advisory Board, Collaborative Alliance for Pancreatic Education and Research, 2012-

present• Member, Advisory Committee, Pancreas Section Councilor, American Gastroenterology

Dr. Binion receiving the Sherman Prize at the 2018 Advances in IBD Conference.

21



Advisory Committee Memberships and Leadership Positions• Abstract Review Board, member, American Association for the Study of Liver Diseases (AASLD),

2015-present• Abstract Review Board, member, Digestive Disease Week (DDW), 2015-present

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases (AASLD), 2007-present• Member, International Society for Hepatic Sinusoidal Research (ISHSR), 2010-present• Member, Society of Toxicology (SOT), 2013-present

Editorships• Ad Hoc Reviewer, Multiple journals (American Journal of Physiology: Gastrointestional and Liver

Physiology; Annals of Hepatology; Archives of Biochemistry and Biophysics; Hepatology; Journal of Pharmacology and Experimental Therapeutics; Journal of Hepatology; Toxicology and Applied Pharmacology; Toxicological Sciences), 2008-present

David G. Binion, MDDr. Binion is an inflammatory bowel disease (IBD) investigator whose career has focused on defining the cellular and molecular mechanisms underlying human chronic gut inflammation and translating that knowledge into improved care for patients suffering from Crohn's disease and ulcerative colitis. His current work centers on Big Data analytics and the development and transformation of the UPMC IBD Registry, a prospective, multi-year, longitudinal natural history registry database of >3,000 consented IBD patients, into a metadata platform for scientific discovery. Through a collaboration with computer scientists from the University of Pittsburgh School of Information Science, this relational database continuously curates and transforms observational clinical information from the electronic medical record (EMR) and maintains >10,000 person-years of associated metadata in a secure data warehouse. Areas of active investigation include: Developing prognostic biomarkers of IBD severity, characterizing the impact of diet and nutrition on IBD natural history, identifying biomarker patterns to predict development of dysplasia/cancer in IBD, identifying predictive biomarkers to guide therapeutic selection in IBD, comparative effectiveness studies in IBD maintenance therapy, defining the impact of surgical anastomotic technique on longterm clinical outcomes in Crohn's disease, use of healthcare charge data as a comprehensive phenotype, defining the impact of Clostridium difficile infection on IBD natural history, characterizing extra-intestinal manifestations--including anemia and autonomic dysfunction--on the natural history of IBD, developing clinical decision support tools to optimize IBD care, and implementing precision medicine.

Advisory Committee Memberships and Leadership Positions• Member, Executive Board, Crohn’s and Colitis Foundation of America, 1999-present

• Director, Translational Inflammatory Bowel Disease Research, University of Pittsburgh, 2008-present

• Co-Director, Inflammatory Bowel Disease Center, University of Pittsburgh, 2008-present• Member, Steering Committee, (SECURE) FDA Mandated Safety Registry UCB Pharma, Inc.,

2009-2019• Medical Director, GI and Nutrition Therapy (GIANT), 2013-present• Director, Nutrition Support Service, 2013-present• Member, Nutrition Subcommittee, UPMC Presbyterian-Shadyside Hospitals, 2013-present• Co-Director, Gastroenterology T32 Training Program, 2018-present

Editorships• Editorial Advisory Board, The American Journal of Gastroenterology, 2007-present• Editorial Advisory Board, World Journal of Gastroenterology, 2007-present• Editorial Advisory Board, Clinical and Translational Science, 2008-present• Editorial Advisory Board, Clinical Gastroenterology and Hepatology, 2014-present

Honors and Awards• Honoree, Best Doctors in America, 2002-present• Honoree, Pittsburgh's Best Doctors, Pittsburgh Magazine, 2014-present• Awardee, Sherman Prize, Sherman Foundation, Advances in IBD Conference, Orlando, FL,

December 2018

Randall E. Brand, MDDr. Brand is a physician-scientist with an extensive background in pancreatic diseases, and his research focuses primarily on the early diagnosis of pancreatic cancer and cystic lesions of the pancreas. He also studies familial pancreatic cancer and other hereditary GI disorders. He is leader of the University of Pittsburgh's Pancreatic Adenocarcinoma Gene-Environment Registry (PAGER). The biospecimen repository, developed as part of the PAGER study, is nationally recognized and serves as an excellent resource for multiple NIH/NC-funded projects as well as for national and international collaborations with outside researchers. Dr. Brand is a key contributor to the Early Detection Research Network, especially in research related to pancreatic cancer and cystic neoplasms. He is currently funded in the network as a principal investigator to lead both a multi-center Pancreatic Cancer Clinical Validation Center and a Biomarker Developmental Laboratory.

Advisory Committee Memberships and Leadership Positions• Director, GI Section and Academic Director, Shadyside Hospital, 2007-present• Director, GI Malignancy Early Detection, Diagnosis and Prevention Program, UPMC, 2007-present• Member, GI Fellowship Committee, University of Pittsburgh, 2007-present• Member, Pancreatic Cancer Clinical Pathways Committee, University of Pittsburgh Medical Center,

2008-present• Member, Collaborative Alliance for Pancreatic Education and Research, 2009-present• Member, Health Sciences Bridge Funding Committee, 2010-present• Chief, Therapeutic Endoscopy, Division of Gastroenterology & Hepatology, University of

Pittsburgh Medical Center, 2011-present• Member, Advisory Board, Collaborative Alliance for Pancreatic Education and Research, 2012-

present• Member, Advisory Committee, Pancreas Section Councilor, American Gastroenterology

Dr. Binion receiving the Sherman Prize at the 2018 Advances in IBD Conference.

22



Association, 2013-present• Director, Interventional Endoscopy Fellowship Training Program, 2013-present• Director, GI State of the Art Lecture Series, 2016-present• Governor of Western PA, American College of Gastroenterology, 2018-present• Appointed Member, National Cancer Institute Pancreas Task Force, 2018-present

Editorships• Ad hoc Reviewer, Clinical Cancer Research, 2000-present• Ad hoc Reviewer, American Journal of Human Genetics, 2001-present• Ad hoc Reviewer, Pancreas, 2001-present• Ad hoc Reviewer, Cancer Epidemiology Biomarkers & Prevention, 2002-present• Advisory Board, Nature Reviews Gastroenterology and Hepatology, 2006-present• Editorial Board, Nature Clinical Practice Gastroenterology & Hepatology, 2006-present• Ad hoc Reviewer, Gut, 2007-present• Ad hoc Reviewer, Familial Cancer, 2010-present• Editorial Board, Annals of Gastroenterology and Hepatology, 2010-present• Ad hoc Reviewer, Clinical Colorectal Cancer, 2011-present• Editorial Board, Case Reports in Gastroenterology, 2011-present

Honors and Awards• Fellow, American Gastroenterological Association, 2007-present• Honoree, Best Doctors, Pittsburgh Magazine, 2012-present

Rhonda Metter Brand, PhDDr. Brand is an Adjunct Associate Professor of Medicine who is engaged in mucosal research related to dermatology and gastroenterology.

Jennifer S. Chennat, MDDr. Chennat is an Associate Professor of Medicine and her research comprises Barrett's esophagus neoplasia, endotherapies for pancreatitis, novel imaging techniques such as confocal endomicroscopy, and endoscopic devices and product designs related to guided visualization and targeted tissue ablation. Her clinical focus is patients who require advanced endoscopic evaluation for disorders such as complex pancreatitis, Barrett's esophagus, and gastrointestinal lumen and pancreato-biliary cancer staging.

Kapil B. Chopra, MDDr. Chopra's research interests center on the cholestatic liver diseases primary sclerosing cholangitis and primary biliary cirrhosis. He has participated in collaborative research projects with the Starzl Transplant Institute and the Liver Cancer Center, and has served as co-investigator on several multicenter trials investigating novel therapies and approaches to the management of viral hepatitis. His research has culminated in 50 scientific presentations at national and international conferences. Dr. Chopra was a co-investigator on numerous NIH-funded research studies including PSC Resource of Genetic Risk, Environment and Synergy Studies (PROGRESS) (Principal Investigator: Dr. K Lazaridis, Mayo Clinic College of Medicine); A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1-Antitrypsin Deficiency (Principal Investigator: Dr. David Perlmutter, Children's Hospital, Pittsburgh); and a prospective study comparing surgical therapies versus interventional radiologic interventions for management of gastrointestinal bleeding in patients with chronic liver disease. In recognition of his role as a

mentor and his contributions to the Clinical Research Scholars Program (CRSP) of the Clinical and Translational Science Institute (CTSI), he was offered a secondary appointment in Clinical and Translational Science at the University of Pittsburgh in September 2012.

Advisory Committee Memberships and Leadership Positions• Board Member, Allegheny Division, American Liver Foundation, 2006-present• Member, Medical Advisory Committee, Allegheny Division, American Liver Foundation, 2006-

present• Chairman, Medical Advisory Committee, Allegheny Division, American Liver Foundation, 2007-

present• Member, Graduate Medical Education Committee, University of Pittsburgh School of Medicine,

2007-present• Member, Advisory Board, PSC Partners Seeking a Cure Medical, 2008-present• Member, UPMC Presbyterian/ Shadyside Hospitals Transplant Patient Safety Council, 2010-

present• Member, Appointment and Promotion Committee, Department of Medicine, University of

Pittsburgh School of Medicine, 2012-present• Board Member, Community Liver Alliance, 2014-present• Medical Director, Comprehensive Liver Program, UPMC Liver and Pancreas Institute, 2014-present• Member, Pharmacy and Therapeutics Committee, UPMC Health Plan, 2016-present

Editorships• Ad hoc Reviewer, Digestive Diseases and Sciences, 2007-present• Ad hoc Reviewer, American Journal of Gastroenterology, 2007-present• Ad hoc Reviewer, Liver Transplantation, 2007-present• Ad hoc Reviewer, Mayo Clinic Proceedings, 2007-present

Rohit Das, MDDr. Das's research interests related to pancreaticobiliary endoscopy. He is particularly interested in endoscopic treatment modalities for recurrent and chronic pancreatitis.

Brian M. Davis, PhDDr. Davis is a Professor of Neurobiology and Medicine whose research focuses on the role of growth factor interaction with sensory fibers that may be responsible for regulating neurogenic inflammation in pancreatic disease. He also investigates the role of the peripheral nervous system in pancreatic cancer pain and metastasis.

Professional Affiliations and Society Memberships• Member, Society for Neurosciences, 1979 - Present• Member, American Gastroenterology Association, 2001 - Present• Member, International Association for the Study of Pain, 2005 - Present

Andres Duarte-Rojo, MD, MS, DScDr. Duarte-Rojo conducts clinical and translational research in disorders of physical function and exercise in advanced liver disease. He is also interested in clinimetrics, with an emphasis on the use of noninvasive assessment of liver disease, and the development of methods to predict clinical outcomes.

23



Association, 2013-present• Director, Interventional Endoscopy Fellowship Training Program, 2013-present• Director, GI State of the Art Lecture Series, 2016-present• Governor of Western PA, American College of Gastroenterology, 2018-present• Appointed Member, National Cancer Institute Pancreas Task Force, 2018-present

Editorships• Ad hoc Reviewer, Clinical Cancer Research, 2000-present• Ad hoc Reviewer, American Journal of Human Genetics, 2001-present• Ad hoc Reviewer, Pancreas, 2001-present• Ad hoc Reviewer, Cancer Epidemiology Biomarkers & Prevention, 2002-present• Advisory Board, Nature Reviews Gastroenterology and Hepatology, 2006-present• Editorial Board, Nature Clinical Practice Gastroenterology & Hepatology, 2006-present• Ad hoc Reviewer, Gut, 2007-present• Ad hoc Reviewer, Familial Cancer, 2010-present• Editorial Board, Annals of Gastroenterology and Hepatology, 2010-present• Ad hoc Reviewer, Clinical Colorectal Cancer, 2011-present• Editorial Board, Case Reports in Gastroenterology, 2011-present

Honors and Awards• Fellow, American Gastroenterological Association, 2007-present• Honoree, Best Doctors, Pittsburgh Magazine, 2012-present

Rhonda Metter Brand, PhDDr. Brand is an Adjunct Associate Professor of Medicine who is engaged in mucosal research related to dermatology and gastroenterology.

Jennifer S. Chennat, MDDr. Chennat is an Associate Professor of Medicine and her research comprises Barrett's esophagus neoplasia, endotherapies for pancreatitis, novel imaging techniques such as confocal endomicroscopy, and endoscopic devices and product designs related to guided visualization and targeted tissue ablation. Her clinical focus is patients who require advanced endoscopic evaluation for disorders such as complex pancreatitis, Barrett's esophagus, and gastrointestinal lumen and pancreato-biliary cancer staging.

Kapil B. Chopra, MDDr. Chopra's research interests center on the cholestatic liver diseases primary sclerosing cholangitis and primary biliary cirrhosis. He has participated in collaborative research projects with the Starzl Transplant Institute and the Liver Cancer Center, and has served as co-investigator on several multicenter trials investigating novel therapies and approaches to the management of viral hepatitis. His research has culminated in 50 scientific presentations at national and international conferences. Dr. Chopra was a co-investigator on numerous NIH-funded research studies including PSC Resource of Genetic Risk, Environment and Synergy Studies (PROGRESS) (Principal Investigator: Dr. K Lazaridis, Mayo Clinic College of Medicine); A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1-Antitrypsin Deficiency (Principal Investigator: Dr. David Perlmutter, Children's Hospital, Pittsburgh); and a prospective study comparing surgical therapies versus interventional radiologic interventions for management of gastrointestinal bleeding in patients with chronic liver disease. In recognition of his role as a

mentor and his contributions to the Clinical Research Scholars Program (CRSP) of the Clinical and Translational Science Institute (CTSI), he was offered a secondary appointment in Clinical and Translational Science at the University of Pittsburgh in September 2012.

Advisory Committee Memberships and Leadership Positions• Board Member, Allegheny Division, American Liver Foundation, 2006-present• Member, Medical Advisory Committee, Allegheny Division, American Liver Foundation, 2006-

present• Chairman, Medical Advisory Committee, Allegheny Division, American Liver Foundation, 2007-

present• Member, Graduate Medical Education Committee, University of Pittsburgh School of Medicine,

2007-present• Member, Advisory Board, PSC Partners Seeking a Cure Medical, 2008-present• Member, UPMC Presbyterian/ Shadyside Hospitals Transplant Patient Safety Council, 2010-

present• Member, Appointment and Promotion Committee, Department of Medicine, University of

Pittsburgh School of Medicine, 2012-present• Board Member, Community Liver Alliance, 2014-present• Medical Director, Comprehensive Liver Program, UPMC Liver and Pancreas Institute, 2014-present• Member, Pharmacy and Therapeutics Committee, UPMC Health Plan, 2016-present

Editorships• Ad hoc Reviewer, Digestive Diseases and Sciences, 2007-present• Ad hoc Reviewer, American Journal of Gastroenterology, 2007-present• Ad hoc Reviewer, Liver Transplantation, 2007-present• Ad hoc Reviewer, Mayo Clinic Proceedings, 2007-present

Rohit Das, MDDr. Das's research interests related to pancreaticobiliary endoscopy. He is particularly interested in endoscopic treatment modalities for recurrent and chronic pancreatitis.

Brian M. Davis, PhDDr. Davis is a Professor of Neurobiology and Medicine whose research focuses on the role of growth factor interaction with sensory fibers that may be responsible for regulating neurogenic inflammation in pancreatic disease. He also investigates the role of the peripheral nervous system in pancreatic cancer pain and metastasis.

Professional Affiliations and Society Memberships• Member, Society for Neurosciences, 1979 - Present• Member, American Gastroenterology Association, 2001 - Present• Member, International Association for the Study of Pain, 2005 - Present

Andres Duarte-Rojo, MD, MS, DScDr. Duarte-Rojo conducts clinical and translational research in disorders of physical function and exercise in advanced liver disease. He is also interested in clinimetrics, with an emphasis on the use of noninvasive assessment of liver disease, and the development of methods to predict clinical outcomes.

24



Richard H. Duerr, MDA Professor of Medicine, Human Genetics, and Clinical and Translational Science at the University of Pittsburgh, Dr. Duerr holds the Inflammatory Bowel Disease Genetic Research Chair and is Co-Director and Scientific Director of the University of Pittsburgh Medical Center Inflammatory Bowel Disease Center--and has been involved in research related to inflammatory bowel disease throughout his career. He leads one of six genetic research centers that comprise the NIH/NIDDK Inflammatory Bowel Disease Genetics Consortium. His research program has had uninterrupted funding from the NIH, CCFA, and other foundations since 1995. He was recently appointed Associate Chief Scientist, Translational Research on the Leadership Team of the Crohn's & Colitis Foundation of America (CCFA) IBD Plexus research and information exchange platform. Dr. Duerr is a member of the American Gastroenterological Association, the American Society of Human Genetics, and CCFA. He has been an invited lecturer in local, national, and international venues, and he has published original inflammatory bowel disease genetics research articles in journals such as Nature, Science, Nature Genetics, American Journal of Human Genetics, and Human Molecular Genetics. He has served on grants review committees for the NIH and CCFA.

Advisory Committee Memberships and Leadership Positions• Chairman, NIDDK IBD Genetics Consortium Genotyping Committee, 2003-present• Chairman, Institutional Data and Safety Monitoring Board Subcommittee, 2006-present• Clinical Research Scholar, Institute for Clinical Research Education, 2009-present• Member, IBD Plexus Integration and Transition Team, Crohn’s & Colitis Foundation of America,

2014-present• Member, Standing Committee for Tenured Faculty Promotions and Appointments, University of

Pittsburgh School of Medicine, 2016-presentProfessional Affiliations and Society Memberships

• Physician Member, Crohn’s and Colitis Foundation, 2007-presentEditorships

• Editor, Genetics Section, Inflammatory Bowel Diseases, 2008-present

Mohannad Dugum, MDDr. Dugum’s research focuses on acute pancreatitis and associated organ failure.

Michael A. Dunn, MDIn a collaboration with colleagues from the Thomas E Starzl Transplantation Institute and the School of Health and Rehabilitation Sciences, Dr. Dunn leads a UPMC hospital-funded initiative to improve the fitness and activity of liver transplant candidates with the objective of producing a 20% decrease in waitlist hospital days and waitlist mortality. Wearable personal-activity monitoring and quantitation of muscle mass with imaging segmentation analysis are being explored as enabling technologies. Dr. Dunn formed and now leads the FLEXIT (Fitness, Life Enhancement and Exercise in Transplantation) Consortium of investigators at the University of California San Francisco, Mayo Clinic Arizona, Cleveland Clinic, Duke University, University of Alberta, and University of Pittsburgh. The consortium is engaged in multi-center collaborations to define, prevent, and reverse physical decline in cirrhosis. Dr. Dunn helped Dr. Binion design and continues to assist in operating a Department of Defense-supported searchable prospective electronic clinical registry for our inflammatory bowel disease team. It has enabled significant advances in disease modeling with over 20 major publications in the last three years. He also serves as the site Principal Investigator of an industry-sponsored

FDA registration trial of obeticholic acid therapy for primary sclerosing cholangitis.Advisory Committee Memberships and Leadership

Positions• Board of Directors, Central Pennsylvania

Veterans Community Initiatives, 2005-present

• Policy Co-Chair, Pennsylvania Diabetes Action Plan, 2006-present

• Associate Chief for Translational Research, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, 2008-present

• Board of Directors, Easter Seals of Western Pennsylvania, 2008-present

• Member, Advisory Panel, U.S. Army Surgeon General on Military Medicine and Prevention, 2008-present

• Board of Directors, National Flag Foundation, 2012-present

• Board of Directors, Pittsburgh Community Liver Alliance, 2014-present• National Medical Society Service Officer, AASLD Federal Agencies Liaison Committee, 2016-

presentHonors and Awards

• Fellow, American Association for the Study of Liver Disease, 2017-present

Kenneth E. Fasanella, MDDr. Fasanella is an Assistant Professor of Medicine whose research includes studying surveillance and risk stratification of pancreatic cystic lesions; biomarkers of risk in Barrett's esophagus; outcomes of endoscopic treatment of high-risk Barrett's esophagus and Barrett's-related neoplasia; appropriate surveillance intervals of gastric stromal tumors; and educational research in endoscopic feedback tools.

Advisory Committee Memberships and Leadership Positions• Member, Education Review Committee, National Pancreas Foundation, 2003-present• Member, Residency Selection Committee, Department of Medicine, University of Pittsburgh

School of Medicine, 2007-present• Member, Common Fellowship Curriculum Committee, 2007-present• Program Director, Gastroenterology Fellowship, 2007-present• Member, Selection Committee, University of Pittsburgh School of Medicine, 2009-present• Course Director, UPMC Gastroenterology Grand Rounds, 2012-present

Professional Affiliations and Society Memberships• Member, North American Pancreas Study Group, 2005-present

Alison J. Faust, MD, MHSDr. Faust conducts research related to viral hepatitis, non-alcoholic fatty liver disease, and alcoholic liver

Dr. Dunn is one of several hepatology faculty in the Division. Divisional liver faculty include (Front row, left to right) Obaid S. Shaikh, MD; Naudia Jonassaint, MD, MHS; Ramon Bataller Alberola, MD, PhD; Vikrant Rachakonda, MD; (Back row, left to right) Mordechai Rabinovitz, MD; Shahid Malik, MD; Andres Duarte-Rojo, MD, MS, DSc; and Michael Dunn, MD.

25



Richard H. Duerr, MDA Professor of Medicine, Human Genetics, and Clinical and Translational Science at the University of Pittsburgh, Dr. Duerr holds the Inflammatory Bowel Disease Genetic Research Chair and is Co-Director and Scientific Director of the University of Pittsburgh Medical Center Inflammatory Bowel Disease Center--and has been involved in research related to inflammatory bowel disease throughout his career. He leads one of six genetic research centers that comprise the NIH/NIDDK Inflammatory Bowel Disease Genetics Consortium. His research program has had uninterrupted funding from the NIH, CCFA, and other foundations since 1995. He was recently appointed Associate Chief Scientist, Translational Research on the Leadership Team of the Crohn's & Colitis Foundation of America (CCFA) IBD Plexus research and information exchange platform. Dr. Duerr is a member of the American Gastroenterological Association, the American Society of Human Genetics, and CCFA. He has been an invited lecturer in local, national, and international venues, and he has published original inflammatory bowel disease genetics research articles in journals such as Nature, Science, Nature Genetics, American Journal of Human Genetics, and Human Molecular Genetics. He has served on grants review committees for the NIH and CCFA.

Advisory Committee Memberships and Leadership Positions• Chairman, NIDDK IBD Genetics Consortium Genotyping Committee, 2003-present• Chairman, Institutional Data and Safety Monitoring Board Subcommittee, 2006-present• Clinical Research Scholar, Institute for Clinical Research Education, 2009-present• Member, IBD Plexus Integration and Transition Team, Crohn’s & Colitis Foundation of America,

2014-present• Member, Standing Committee for Tenured Faculty Promotions and Appointments, University of

Pittsburgh School of Medicine, 2016-presentProfessional Affiliations and Society Memberships

• Physician Member, Crohn’s and Colitis Foundation, 2007-presentEditorships

• Editor, Genetics Section, Inflammatory Bowel Diseases, 2008-present

Mohannad Dugum, MDDr. Dugum’s research focuses on acute pancreatitis and associated organ failure.

Michael A. Dunn, MDIn a collaboration with colleagues from the Thomas E Starzl Transplantation Institute and the School of Health and Rehabilitation Sciences, Dr. Dunn leads a UPMC hospital-funded initiative to improve the fitness and activity of liver transplant candidates with the objective of producing a 20% decrease in waitlist hospital days and waitlist mortality. Wearable personal-activity monitoring and quantitation of muscle mass with imaging segmentation analysis are being explored as enabling technologies. Dr. Dunn formed and now leads the FLEXIT (Fitness, Life Enhancement and Exercise in Transplantation) Consortium of investigators at the University of California San Francisco, Mayo Clinic Arizona, Cleveland Clinic, Duke University, University of Alberta, and University of Pittsburgh. The consortium is engaged in multi-center collaborations to define, prevent, and reverse physical decline in cirrhosis. Dr. Dunn helped Dr. Binion design and continues to assist in operating a Department of Defense-supported searchable prospective electronic clinical registry for our inflammatory bowel disease team. It has enabled significant advances in disease modeling with over 20 major publications in the last three years. He also serves as the site Principal Investigator of an industry-sponsored

FDA registration trial of obeticholic acid therapy for primary sclerosing cholangitis.Advisory Committee Memberships and Leadership

Positions• Board of Directors, Central Pennsylvania

Veterans Community Initiatives, 2005-present

• Policy Co-Chair, Pennsylvania Diabetes Action Plan, 2006-present

• Associate Chief for Translational Research, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, 2008-present

• Board of Directors, Easter Seals of Western Pennsylvania, 2008-present

• Member, Advisory Panel, U.S. Army Surgeon General on Military Medicine and Prevention, 2008-present

• Board of Directors, National Flag Foundation, 2012-present

• Board of Directors, Pittsburgh Community Liver Alliance, 2014-present• National Medical Society Service Officer, AASLD Federal Agencies Liaison Committee, 2016-

presentHonors and Awards

• Fellow, American Association for the Study of Liver Disease, 2017-present

Kenneth E. Fasanella, MDDr. Fasanella is an Assistant Professor of Medicine whose research includes studying surveillance and risk stratification of pancreatic cystic lesions; biomarkers of risk in Barrett's esophagus; outcomes of endoscopic treatment of high-risk Barrett's esophagus and Barrett's-related neoplasia; appropriate surveillance intervals of gastric stromal tumors; and educational research in endoscopic feedback tools.

Advisory Committee Memberships and Leadership Positions• Member, Education Review Committee, National Pancreas Foundation, 2003-present• Member, Residency Selection Committee, Department of Medicine, University of Pittsburgh

School of Medicine, 2007-present• Member, Common Fellowship Curriculum Committee, 2007-present• Program Director, Gastroenterology Fellowship, 2007-present• Member, Selection Committee, University of Pittsburgh School of Medicine, 2009-present• Course Director, UPMC Gastroenterology Grand Rounds, 2012-present

Professional Affiliations and Society Memberships• Member, North American Pancreas Study Group, 2005-present

Alison J. Faust, MD, MHSDr. Faust conducts research related to viral hepatitis, non-alcoholic fatty liver disease, and alcoholic liver

Dr. Dunn is one of several hepatology faculty in the Division. Divisional liver faculty include (Front row, left to right) Obaid S. Shaikh, MD; Naudia Jonassaint, MD, MHS; Ramon Bataller Alberola, MD, PhD; Vikrant Rachakonda, MD; (Back row, left to right) Mordechai Rabinovitz, MD; Shahid Malik, MD; Andres Duarte-Rojo, MD, MS, DSc; and Michael Dunn, MD.

26



disease.Advisory Committee Memberships and Leadership Positions

• Member, American Association for the Study of Liver Diseases, Technology & Social Media Committee, November 2016-present

Fadi F. Francis, MDDr. Francis examines Hepatitis C treatment and pre- and post-liver transplantation.

Advisory Committee Memberships and Leadership Positions• Medical Director, Liver Transplantation, VA Pittsburgh Healthcare Systems, 2005-present

Swaytha R. Ganesh, MDDr. Ganesh is an Assistant Professor of Medicine investigating issues related to living donor liver transplants and drug metabolism in patients post-living donor transplant. Dr. Ganesh also researches the safety and preliminary efficacy of donor-derived regulatory dendritic cell infusion and immunosuppression withdrawal in living donor transplant recipients, as well as Remodulin and ischemic reperfusion injury in patients post-liver transplant.

Michael S. Gold, PhDDr. Gold is a Professor of Anesthesiology whose research is focused around the clinical features of a number of pain syndromes. These observations include the following: 1) many pain syndromes are unique to a particular part of the body such as the head in migraine, the temporomandibular joint in temporomandibular disorder (TMD), or the colon in inflammatory bowel disease (IBD); 2) many pain syndromes such as migraine, TMD, and IBD occur with a greater prevalence, severity, and/or duration in women than in men; 3) many pain syndromes are associated with changes in the excitability of primary afferent neurons; 4) there are time dependent changes in the mechanisms underlying pain syndromes; and 5) different types of injuries (i.e., inflammation or nerve injury) are differentially sensitive to therapeutic interventions. These observations led to specific hypotheses that are tested in ongoing studies in the Gold laboratory. These include 1) characterizing the mechanisms underlying inflammation-induced changes in the evoked Ca2+ transients in sensory neurons, 2) characterizing the mechanisms underlying the inflammatory mediator-induced sensitization of dural afferents, 3) characterizing the influence of estrogen on the excitability of spinal and trigeminal ganglion neurons, 4) characterizing the mechanisms underlying the link between stress and migraine, 5) characterizing the role of changes in inhibitory receptors, in particular GABA, in injury-induced increases in sensitivity, and 6) identification of ways to maximize the therapeutic utility of local anesthetics. The ultimate goal of these studies is to identify novel targets for the development of therapeutic interventions for the treatment of pain.

Julia B. Greer, MD, MPHDr. Greer investigates cancer epidemiology as it relates to colon and pancreatic cancer, acute and chronic pancreatitis, nutrition, inflammatory bowel disease risk factors and case management, bioinformatics, and medical education in digestion and nutrition.

Advisory Committee Memberships and Leadership Positions• Member, Wayne Fusaro Pancreatic Cancer Research Foundation, 2005-present• Member, Minority Affairs Consortium, 2006-present

• Member, Complementary Medicine Interest Group, Integrative Medicine Center Pittsburgh, 2007-present

• Member, Interviewing Committee, University of Pittsburgh School of Medicine, 2009-present• Member, Guaranteed Admit Interviewing Program Committee, University of Pittsburgh School of

Medicine, 2011-present• Admissions Committee, University of Pittsburgh School of Medicine, 2012-present• Member, NBME Article Reviewer for USMLE, 2012-present

Editorships• Editorial Board, World Journal of Gastroenterology, 2006-present• Editor, Pitt Digest, 2012-present• Associate Editor, Inflammatory Bowel Diseases, 2014-present• Section Editor, IBD Case Series, Inflammatory Bowel Diseases, 2014-present

Janet R. Harrison, MDDr. Harrison’s research interests include Inflammatory bowel disease and women’s health.

Elyse R. Johnston, MDDr. Johnston's research investigates enhanced methodology for quality healthcare performance and patient safety.

Naudia L. Jonassaint, MD, MHSDr. Jonassaint researches specific biologic markers involved in the development and progression of liver disease in both the pre- and posttransplant populations, with a focus on disparities in liver transplant outcomes. This research program also explores why some patients experience rapid fibrosis progression or accelerated graft loss post-transplant.

Advisory Committee Memberships and Leadership Positions• Advisory Member, Johns Hopkins Second Decade Society, 2009-present• Clinical Preceptor, Gastroenterology and Hepatology, McKeesport Hospital, 2014-present• Member, Diversity Committee, American Association for the Study of Liver Diseases, 2016-present• Vice Chair for Diversity and Inclusion, Department of Medicine, University of Pittsburgh, 2018-

presentMajor Lectureships and Seminars

• Invited Lecture, "End Stage Liver Dsiease and End of Life Care," Palliative Medicine Grand Rounds, UPMC, 2018

Asif Khalid, MDAn Associate Professor of Medicine, Dr. Khalid's research involves pancreatic tumors and cysts, EUS, ERCP, pancreatitis, molecular diagnoses, and early cancer detection.

Advisory Committee Memberships and Leadership Positions• GI Section Chief, VA Pittsburgh Healthcare System, 2004-present• Member, Adverse Events & Procedures Committee, VA Pittsburgh Health System, 2004-present

Professional Affiliations and Society Memberships• Member, American Society for Gastrointestinal Endoscopy, 2008-present

27



disease.Advisory Committee Memberships and Leadership Positions

• Member, American Association for the Study of Liver Diseases, Technology & Social Media Committee, November 2016-present

Fadi F. Francis, MDDr. Francis examines Hepatitis C treatment and pre- and post-liver transplantation.

Advisory Committee Memberships and Leadership Positions• Medical Director, Liver Transplantation, VA Pittsburgh Healthcare Systems, 2005-present

Swaytha R. Ganesh, MDDr. Ganesh is an Assistant Professor of Medicine investigating issues related to living donor liver transplants and drug metabolism in patients post-living donor transplant. Dr. Ganesh also researches the safety and preliminary efficacy of donor-derived regulatory dendritic cell infusion and immunosuppression withdrawal in living donor transplant recipients, as well as Remodulin and ischemic reperfusion injury in patients post-liver transplant.

Michael S. Gold, PhDDr. Gold is a Professor of Anesthesiology whose research is focused around the clinical features of a number of pain syndromes. These observations include the following: 1) many pain syndromes are unique to a particular part of the body such as the head in migraine, the temporomandibular joint in temporomandibular disorder (TMD), or the colon in inflammatory bowel disease (IBD); 2) many pain syndromes such as migraine, TMD, and IBD occur with a greater prevalence, severity, and/or duration in women than in men; 3) many pain syndromes are associated with changes in the excitability of primary afferent neurons; 4) there are time dependent changes in the mechanisms underlying pain syndromes; and 5) different types of injuries (i.e., inflammation or nerve injury) are differentially sensitive to therapeutic interventions. These observations led to specific hypotheses that are tested in ongoing studies in the Gold laboratory. These include 1) characterizing the mechanisms underlying inflammation-induced changes in the evoked Ca2+ transients in sensory neurons, 2) characterizing the mechanisms underlying the inflammatory mediator-induced sensitization of dural afferents, 3) characterizing the influence of estrogen on the excitability of spinal and trigeminal ganglion neurons, 4) characterizing the mechanisms underlying the link between stress and migraine, 5) characterizing the role of changes in inhibitory receptors, in particular GABA, in injury-induced increases in sensitivity, and 6) identification of ways to maximize the therapeutic utility of local anesthetics. The ultimate goal of these studies is to identify novel targets for the development of therapeutic interventions for the treatment of pain.

Julia B. Greer, MD, MPHDr. Greer investigates cancer epidemiology as it relates to colon and pancreatic cancer, acute and chronic pancreatitis, nutrition, inflammatory bowel disease risk factors and case management, bioinformatics, and medical education in digestion and nutrition.

Advisory Committee Memberships and Leadership Positions• Member, Wayne Fusaro Pancreatic Cancer Research Foundation, 2005-present• Member, Minority Affairs Consortium, 2006-present

• Member, Complementary Medicine Interest Group, Integrative Medicine Center Pittsburgh, 2007-present

• Member, Interviewing Committee, University of Pittsburgh School of Medicine, 2009-present• Member, Guaranteed Admit Interviewing Program Committee, University of Pittsburgh School of

Medicine, 2011-present• Admissions Committee, University of Pittsburgh School of Medicine, 2012-present• Member, NBME Article Reviewer for USMLE, 2012-present

Editorships• Editorial Board, World Journal of Gastroenterology, 2006-present• Editor, Pitt Digest, 2012-present• Associate Editor, Inflammatory Bowel Diseases, 2014-present• Section Editor, IBD Case Series, Inflammatory Bowel Diseases, 2014-present

Janet R. Harrison, MDDr. Harrison’s research interests include Inflammatory bowel disease and women’s health.

Elyse R. Johnston, MDDr. Johnston's research investigates enhanced methodology for quality healthcare performance and patient safety.

Naudia L. Jonassaint, MD, MHSDr. Jonassaint researches specific biologic markers involved in the development and progression of liver disease in both the pre- and posttransplant populations, with a focus on disparities in liver transplant outcomes. This research program also explores why some patients experience rapid fibrosis progression or accelerated graft loss post-transplant.

Advisory Committee Memberships and Leadership Positions• Advisory Member, Johns Hopkins Second Decade Society, 2009-present• Clinical Preceptor, Gastroenterology and Hepatology, McKeesport Hospital, 2014-present• Member, Diversity Committee, American Association for the Study of Liver Diseases, 2016-present• Vice Chair for Diversity and Inclusion, Department of Medicine, University of Pittsburgh, 2018-

presentMajor Lectureships and Seminars

• Invited Lecture, "End Stage Liver Dsiease and End of Life Care," Palliative Medicine Grand Rounds, UPMC, 2018

Asif Khalid, MDAn Associate Professor of Medicine, Dr. Khalid's research involves pancreatic tumors and cysts, EUS, ERCP, pancreatitis, molecular diagnoses, and early cancer detection.

Advisory Committee Memberships and Leadership Positions• GI Section Chief, VA Pittsburgh Healthcare System, 2004-present• Member, Adverse Events & Procedures Committee, VA Pittsburgh Health System, 2004-present

Professional Affiliations and Society Memberships• Member, American Society for Gastrointestinal Endoscopy, 2008-present

28



Honors and Awards• Fellow, American College of Gastroenterology, 2008-present

Michael J. Kingsley, MDAs a Clinical Assistant Professor of Medicine, Dr. Kingsley is interested in GI motility clinical trials and translational functional bowel studies.

Professional Affiliations and Society Memberships• Member, American College of Gastroenterology, 2013-present• Member, American Gastroenterological Association, 2013-present• Member, American Society for Gastrointestinal Endoscopy, 2013-present• Member, American Neurogastroenterology and Motility Society, 2016-present

David J. Levinthal, MD, PhDDr. Levinthal's lab uses both neuroanatomical tracing and neurophysiological techniques to explore the neural basis for central nervous system influences over autonomic regulation in both health and disease. Dr. Levinthal centers his research on the neural mechanisms by which the cerebral cortex influences GI tract function. Initial studies have uncovered the surprising finding that a visceromotor map of sympathetic function is embedded within the classic cortical somatotopic map of motor function. Further work is aimed at understanding the cortical regions that influence vagal function. The goal of this effort is to use the visceral maps to guide brain stimulation as a means to influence GI tract function. This line of work will lead to the development of brain-based therapies for those with forms of severe GI dysfunction refractory to standard treatments.

Advisory Committee Memberships and Leadership Positions• Member, Quality Initiative Steering Committee, Division of Gastroenterology, Hepatology, and

Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, 2014-present• Member, GI Research (non-T32) Steering Committee, Division of Gastroenterology, Hepatology,

and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, 2015-present• Invited Member, Adult Cyclic Vomiting Syndrome Clinical Guidelines Development Committee,

co-sponsored by Cyclical Vomiting Syndrome Association and American Neurogastroenterology and Motility Society, 2015-present

• Invited Member, American Gastroenterological Association Institute Research Awards Panel, 2015-present

• Director, Neurogastroenterology & Motility Center, Division of GI, University of Pittsburgh Medical Center, 2016-present

• Vice-Chair, Functional GI and Motility Disorders Pilot Research Award Review Committee, AGA–Rome Foundation, 2016-present

Editorships• Associate Editor, Clinical and Translational Gastroenterology, 2017-present• Editorial Board, Frontier in Neuroscience: Autonomic Neuroscience, 2018-present• Editorial Board, Physiological Reports, 2018-present• Ad Hoc Reviewer, Multiple journals (American Journal of Gastroenterology, Neurogastroenterology

and Motility, Clinical and Translational Gastroenterology, World Journal of Gastroenterology, ACG Case Reports Journal, European journal of Gastroenterology & Hepatology, Experimental Brain Research, Cerebral Cortex, Journal of Neuroscience, Acta Neurologica Scandinavica, International

Neuropsychiatric Disease Journal, Nephrology Dialysis Transplantation, British Journal of Pharmaceutical Research, British Journal of Medicine and Medical Research, Irish Journal of Medical Science, Journal of Clinical Pharmacy and Therapeutics, Journal of Basic and Applied Research International), 2018-present

Honors and Awards• National Research Award, International

Foundation for Gastrointestinal Disorders (IFFGD), Digestive Disease Week (DDW), San Diego, CA, May 2019

Yang Liu, PhDThe laboratory of Dr. Yang Liu works to develop personalized approaches to improve early cancer detection. Current clinical practice relies on a one-shoe-fits-all-approach, which screens the entire at-risk population to identify a small percentage of truly high-risk patients, as with colonoscopy and mammography. Frequent, invasive surveillance of patients at risk for developing cancer carries financial, physical, and emotional burdens and can do more harm than good to the patients. Given that nuclear architecture is one of the hallmarks in cancer diagnostics, the lab's premise is based on nanoscale nuclear architecture mapping to identify earlier and more accurate markers and to understand the characteristic alteration of nanoscale (i.e., less than 100 nm) nuclear architecture in cancer initiation and progression. Current tools to visualize nuclear architecture are mostly limited to microscale. The lab's multi-disciplinary team integrates optics, physics, engineering, bioinformatics, chemistry, biology, and clinical medicine, and develops imaging technologies to address this highly unmet clinical need. Current projects include: (1) Development of clinically applicable imaging technology for the high-throughput nanoscale nuclear architecture mapping (nanoNAM) of clinical samples to predict early-cancer progression in inflammatory bowel disease (IBD), Barrett's esophagus and breast pre-cancerous lesions prior to the detection of clinically significant lesions; (2) Development of high-throughput super-resolution fluorescence nanoscopy (STORM, PALM) for nanoscale imaging of chromatin organization and epigenetics in cancer initiation and progression; and, (3) Development of 3D super-resolution fluorescence nanoscopy for imaging thick tissue.

Advisory Committee Memberships and Leadership Positions• Consultant, NanoVision Diagnostics, 2014-present• Course Director, GI Research Rounds, Division of Gastroenterology, Hepatology, and Nutrition,

Department of Medicine, University of Pittsburgh School of Medicine, 2015-presentProfessional Affiliations and Society Memberships

• Member, Optical Society of America, 2003-present• Member, International Society for Optical Engineering, 2003-present

Editorships• Editorial Board, Scientific Reports, 2016-present

Hongqiang Ma, PhD

Dr. Liu is currently developing high-throughput super-resolution fluorescence nanoscopy, including WindSTORM, for imaging of chromatin organization and epigenetics in cancer initiation and progression. Here, conventional imaging on the left is compared to the imaging achieved through WindSTORM on the right.

29



Honors and Awards• Fellow, American College of Gastroenterology, 2008-present

Michael J. Kingsley, MDAs a Clinical Assistant Professor of Medicine, Dr. Kingsley is interested in GI motility clinical trials and translational functional bowel studies.

Professional Affiliations and Society Memberships• Member, American College of Gastroenterology, 2013-present• Member, American Gastroenterological Association, 2013-present• Member, American Society for Gastrointestinal Endoscopy, 2013-present• Member, American Neurogastroenterology and Motility Society, 2016-present

David J. Levinthal, MD, PhDDr. Levinthal's lab uses both neuroanatomical tracing and neurophysiological techniques to explore the neural basis for central nervous system influences over autonomic regulation in both health and disease. Dr. Levinthal centers his research on the neural mechanisms by which the cerebral cortex influences GI tract function. Initial studies have uncovered the surprising finding that a visceromotor map of sympathetic function is embedded within the classic cortical somatotopic map of motor function. Further work is aimed at understanding the cortical regions that influence vagal function. The goal of this effort is to use the visceral maps to guide brain stimulation as a means to influence GI tract function. This line of work will lead to the development of brain-based therapies for those with forms of severe GI dysfunction refractory to standard treatments.

Advisory Committee Memberships and Leadership Positions• Member, Quality Initiative Steering Committee, Division of Gastroenterology, Hepatology, and

Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, 2014-present• Member, GI Research (non-T32) Steering Committee, Division of Gastroenterology, Hepatology,

and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, 2015-present• Invited Member, Adult Cyclic Vomiting Syndrome Clinical Guidelines Development Committee,

co-sponsored by Cyclical Vomiting Syndrome Association and American Neurogastroenterology and Motility Society, 2015-present

• Invited Member, American Gastroenterological Association Institute Research Awards Panel, 2015-present

• Director, Neurogastroenterology & Motility Center, Division of GI, University of Pittsburgh Medical Center, 2016-present

• Vice-Chair, Functional GI and Motility Disorders Pilot Research Award Review Committee, AGA–Rome Foundation, 2016-present

Editorships• Associate Editor, Clinical and Translational Gastroenterology, 2017-present• Editorial Board, Frontier in Neuroscience: Autonomic Neuroscience, 2018-present• Editorial Board, Physiological Reports, 2018-present• Ad Hoc Reviewer, Multiple journals (American Journal of Gastroenterology, Neurogastroenterology

and Motility, Clinical and Translational Gastroenterology, World Journal of Gastroenterology, ACG Case Reports Journal, European journal of Gastroenterology & Hepatology, Experimental Brain Research, Cerebral Cortex, Journal of Neuroscience, Acta Neurologica Scandinavica, International

Neuropsychiatric Disease Journal, Nephrology Dialysis Transplantation, British Journal of Pharmaceutical Research, British Journal of Medicine and Medical Research, Irish Journal of Medical Science, Journal of Clinical Pharmacy and Therapeutics, Journal of Basic and Applied Research International), 2018-present

Honors and Awards• National Research Award, International

Foundation for Gastrointestinal Disorders (IFFGD), Digestive Disease Week (DDW), San Diego, CA, May 2019

Yang Liu, PhDThe laboratory of Dr. Yang Liu works to develop personalized approaches to improve early cancer detection. Current clinical practice relies on a one-shoe-fits-all-approach, which screens the entire at-risk population to identify a small percentage of truly high-risk patients, as with colonoscopy and mammography. Frequent, invasive surveillance of patients at risk for developing cancer carries financial, physical, and emotional burdens and can do more harm than good to the patients. Given that nuclear architecture is one of the hallmarks in cancer diagnostics, the lab's premise is based on nanoscale nuclear architecture mapping to identify earlier and more accurate markers and to understand the characteristic alteration of nanoscale (i.e., less than 100 nm) nuclear architecture in cancer initiation and progression. Current tools to visualize nuclear architecture are mostly limited to microscale. The lab's multi-disciplinary team integrates optics, physics, engineering, bioinformatics, chemistry, biology, and clinical medicine, and develops imaging technologies to address this highly unmet clinical need. Current projects include: (1) Development of clinically applicable imaging technology for the high-throughput nanoscale nuclear architecture mapping (nanoNAM) of clinical samples to predict early-cancer progression in inflammatory bowel disease (IBD), Barrett's esophagus and breast pre-cancerous lesions prior to the detection of clinically significant lesions; (2) Development of high-throughput super-resolution fluorescence nanoscopy (STORM, PALM) for nanoscale imaging of chromatin organization and epigenetics in cancer initiation and progression; and, (3) Development of 3D super-resolution fluorescence nanoscopy for imaging thick tissue.

Advisory Committee Memberships and Leadership Positions• Consultant, NanoVision Diagnostics, 2014-present• Course Director, GI Research Rounds, Division of Gastroenterology, Hepatology, and Nutrition,

Department of Medicine, University of Pittsburgh School of Medicine, 2015-presentProfessional Affiliations and Society Memberships

• Member, Optical Society of America, 2003-present• Member, International Society for Optical Engineering, 2003-present

Editorships• Editorial Board, Scientific Reports, 2016-present

Hongqiang Ma, PhD

Dr. Liu is currently developing high-throughput super-resolution fluorescence nanoscopy, including WindSTORM, for imaging of chromatin organization and epigenetics in cancer initiation and progression. Here, conventional imaging on the left is compared to the imaging achieved through WindSTORM on the right.

30



Dr. Ma’s research focuses on the development of personalized approaches to improve early cancer detection. Dr. Ma and the lab of Dr. Yang Liu use nanoscale nuclear architecture mapping to identify earlier and more accurate markers to understand the characteristic alteration of cancer initiation and progression. The lab’s technical expertise studies high-throughput, low-cost super-resolution fluorescence microscopy, and high-speed image reconstruction algorithm development.

Shahid M. Malik, MDDr. Malik’s research focuses on outcomes in patients with end stage liver disease/cirrhosis and post-liver transplant.

Advisory Committee Memberships and Leadership Positions• Course Director, Hepatology Case Conference Series, 2011-present• Co-Director, Portal Hypertension Case Conference, 2012-present• Lecturer, GI State of the Art (SOTA) Lecture Series, UPMC, 2012-present• Member, GI Fellowship Education Committee, 2012-present• Associate Program Director, Transplant Hepatology Fellowship Program, 2012-present• Co-Director, Liver Outreach Program, 2012-present

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases, 2010-present• Member, PA Society of Gastroenterology, 2014-present

Editorships• Ad hoc Reviewer, British Medical Journal, 2012-present• Ad hoc Reviewer, American Journal of Transplantation, 2012-present• Ad hoc Reviewer, Liver Transplantation, 2013-present

James B. McGee, MDAn Associate Professor of Medicine, Dr. McGee's research efforts center on the effectiveness of technology-based education, with a focus on simulation and web-based learning. This research applies virtual patient simulation, technical standards, and education analytics (big data) to improve clinical decision-making and educational outcomes.

Advisory Committee Memberships and Leadership Positions• Director, Laboratory for Educational Technology, University of Pittsburgh School of Medicine,

2001-present• Member, Council on Academic Computing (University-level Committee), 2003-present• Member, Curriculum Development and New Initiatives Committee, 2004-present• Member, Computer Technology Subcommittee, American Gastroenterological Association, 2004-

present• Assistant Dean, Medical Education Technology, 2004-present• Chairman, Consortium on Medical Education Technology, American Association of Medical

Colleges, 2005-present• Reviewer, Association of American Medical Colleges, 2005-present• Reviewer, American Medical Informatics Association, 2005-present• Advisory Board, Health Sciences Online, 2005-present• Executive Committee, MedBiquitous, 2007-present• Member, LCME Task Force, American Association of Medical Colleges, 2007-present

• Chairman, Working Group on Virtual Patients, MedBiquitous, 2007-present• Member, Emerging Technologies Task Force, American Gastroenterological Association, 2015-

presentProfessional Affiliations and Society Memberships

• Member, Academy of Master Educators, University of Pittsburgh School of Medicine, 2007-present

Editorships• Reviewer, Medical Teacher (journal), 2006-present• Editorial Board, American Association of Medical Colleges, MedEdPortal, 2006-present• Reviewer, International Journal of Medical Informatics, 2007-present• Editor for Online Education, American Gastroenterological Association, 2007-present

Kevin M. McGrath, MDDr. McGrath investigates endotherapy for the management of Barrett's esophagus and superficial esophageal cancer, evaluation of pancreatic cystic lesions and cyst aspirate analysis, and EUS-guided tissue acquisition.

Advisory Committee Memberships and Leadership Positions• Director, Endoscopic Ultrasound, 2001-present• Director, GI Endoscopy Lab, 2003-present• Course Director, EUS Conference, 2004-present• Co-Director, Barrett’s Esophagus Specialty Treatment Clinic, UPMC, 2008-present• Leader, Gastroenterology Fellows/Peer Faculty, 2008-present

Editorships• Ad hoc Reviewer, American Journal of Gastroenterology, 1998-present• Ad hoc Reviewer, Digestive Diseases and Science, 2002-present• Ad hoc Reviewer, Endoscopy, 2005-present• Ad hoc Reviewer, Diseases of the Esophagus, 2006-present• Ad hoc Reviewer, Journal of Clinical Gastroenterology, 2006-present• Ad hoc Reviewer, Journal of Clinical Oncology, Pancreatology, and Gastrointestinal Endoscopy,

2006-present• Ad hoc Reviewer, Pancreatology, 2006-present• Ad hoc Reviewer, Digestive and Liver Disease, 2007-present• Ad hoc Reviewer, Scandinavian Journal of Gastroenterology, 2008-present• Ad hoc Reviewer, Annals of Thoracic Surgery, 2009-present• Editorial Review Board, Gastrointestinal Endoscopy, 2012-present• Ad hoc Reviewer, Gastroenterology and Hepatology, 2013-present


Satdarshan (Paul) Singh Monga, MDThe Monga lab is focused on understanding the molecular and cellular basis of normal liver characteristics such as development, regeneration, metabolism and growth as well as liver pathologies such as neoplasms (HCC and hepatoblastoma), fibrosis, cirrhosis, alcoholic liver disease, non-alcoholic fatty liver disease, and

31



Dr. Ma’s research focuses on the development of personalized approaches to improve early cancer detection. Dr. Ma and the lab of Dr. Yang Liu use nanoscale nuclear architecture mapping to identify earlier and more accurate markers to understand the characteristic alteration of cancer initiation and progression. The lab’s technical expertise studies high-throughput, low-cost super-resolution fluorescence microscopy, and high-speed image reconstruction algorithm development.

Shahid M. Malik, MDDr. Malik’s research focuses on outcomes in patients with end stage liver disease/cirrhosis and post-liver transplant.

Advisory Committee Memberships and Leadership Positions• Course Director, Hepatology Case Conference Series, 2011-present• Co-Director, Portal Hypertension Case Conference, 2012-present• Lecturer, GI State of the Art (SOTA) Lecture Series, UPMC, 2012-present• Member, GI Fellowship Education Committee, 2012-present• Associate Program Director, Transplant Hepatology Fellowship Program, 2012-present• Co-Director, Liver Outreach Program, 2012-present

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases, 2010-present• Member, PA Society of Gastroenterology, 2014-present

Editorships• Ad hoc Reviewer, British Medical Journal, 2012-present• Ad hoc Reviewer, American Journal of Transplantation, 2012-present• Ad hoc Reviewer, Liver Transplantation, 2013-present

James B. McGee, MDAn Associate Professor of Medicine, Dr. McGee's research efforts center on the effectiveness of technology-based education, with a focus on simulation and web-based learning. This research applies virtual patient simulation, technical standards, and education analytics (big data) to improve clinical decision-making and educational outcomes.

Advisory Committee Memberships and Leadership Positions• Director, Laboratory for Educational Technology, University of Pittsburgh School of Medicine,

2001-present• Member, Council on Academic Computing (University-level Committee), 2003-present• Member, Curriculum Development and New Initiatives Committee, 2004-present• Member, Computer Technology Subcommittee, American Gastroenterological Association, 2004-

present• Assistant Dean, Medical Education Technology, 2004-present• Chairman, Consortium on Medical Education Technology, American Association of Medical

Colleges, 2005-present• Reviewer, Association of American Medical Colleges, 2005-present• Reviewer, American Medical Informatics Association, 2005-present• Advisory Board, Health Sciences Online, 2005-present• Executive Committee, MedBiquitous, 2007-present• Member, LCME Task Force, American Association of Medical Colleges, 2007-present

• Chairman, Working Group on Virtual Patients, MedBiquitous, 2007-present• Member, Emerging Technologies Task Force, American Gastroenterological Association, 2015-

presentProfessional Affiliations and Society Memberships

• Member, Academy of Master Educators, University of Pittsburgh School of Medicine, 2007-present

Editorships• Reviewer, Medical Teacher (journal), 2006-present• Editorial Board, American Association of Medical Colleges, MedEdPortal, 2006-present• Reviewer, International Journal of Medical Informatics, 2007-present• Editor for Online Education, American Gastroenterological Association, 2007-present

Kevin M. McGrath, MDDr. McGrath investigates endotherapy for the management of Barrett's esophagus and superficial esophageal cancer, evaluation of pancreatic cystic lesions and cyst aspirate analysis, and EUS-guided tissue acquisition.

Advisory Committee Memberships and Leadership Positions• Director, Endoscopic Ultrasound, 2001-present• Director, GI Endoscopy Lab, 2003-present• Course Director, EUS Conference, 2004-present• Co-Director, Barrett’s Esophagus Specialty Treatment Clinic, UPMC, 2008-present• Leader, Gastroenterology Fellows/Peer Faculty, 2008-present

Editorships• Ad hoc Reviewer, American Journal of Gastroenterology, 1998-present• Ad hoc Reviewer, Digestive Diseases and Science, 2002-present• Ad hoc Reviewer, Endoscopy, 2005-present• Ad hoc Reviewer, Diseases of the Esophagus, 2006-present• Ad hoc Reviewer, Journal of Clinical Gastroenterology, 2006-present• Ad hoc Reviewer, Journal of Clinical Oncology, Pancreatology, and Gastrointestinal Endoscopy,

2006-present• Ad hoc Reviewer, Pancreatology, 2006-present• Ad hoc Reviewer, Digestive and Liver Disease, 2007-present• Ad hoc Reviewer, Scandinavian Journal of Gastroenterology, 2008-present• Ad hoc Reviewer, Annals of Thoracic Surgery, 2009-present• Editorial Review Board, Gastrointestinal Endoscopy, 2012-present• Ad hoc Reviewer, Gastroenterology and Hepatology, 2013-present


Satdarshan (Paul) Singh Monga, MDThe Monga lab is focused on understanding the molecular and cellular basis of normal liver characteristics such as development, regeneration, metabolism and growth as well as liver pathologies such as neoplasms (HCC and hepatoblastoma), fibrosis, cirrhosis, alcoholic liver disease, non-alcoholic fatty liver disease, and

32



others. This research focus incorporates studies on cell proliferation, adhesion, differentiation, invasion, apoptosis, metabolism, and on stem cells in adult, fetal, and embryonic livers.

Stephen J.D. O'Keefe, MBBS, MD, MScDr. O’Keefe performs translational research into the physiological and pathophysiological responses to feeding and nutritional deprivation. He has received NIH R01 grant support for his studies on the physiological effects of feeding in pancreatic enzyme synthesis in humans with and without disease, the optimal feeding in patients with severe acute pancreatitis, and, most recently, the role of diet, the microbiome, and its metabolites in determining colon cancer risk in extreme-risk Alaska Natives, high-risk African Americans (AA), and minimal risk rural South Africans (NA). His pivotal 2015 study in Nature Communications showed that switching the diets of AA and NA (i.e., Americans were given a traditional African diet high in fiber, low in meat and fat, while Africans were given a westernized diet high in meant and fat and low in fiber) led to profound changes in the colonic microbiome and its metabolome and reciprocal changes in colonic mucosal biomarkers of cancer risk within two weeks. This supports the hypothesis that diet drives colon cancer risk and that it is largely preventable by a high fiber diet. Studies are underway in Alaska to determine whether fiber supplementation will annul the health disparity and extreme rates of colon cancer risk and mortality in Alaska Natives. Finally, Dr. O’Keefe is partnering with the University of Stellenbosch in South Africa to direct the African Microbiome Institute to study the ecology of the microbiome through the Faculties of Medicine, Agrisciences, and Plant Biology, with the overarching aim of improving the health of all Africans.

Study Sections• NCI-NIH Study Sections (special interest groups and programs), 2003-present

Advisory Committee Memberships and Leadership Positions• External Advisory Committee, Division of Nutritional Sciences, UIUC, 2015-present

Editorships• Associate Editor, Frontiers in Gastroenterology Physiology and Science, 2010-present• Assistant Editor-in-Chief, World Journal of Gastroenterology, 2011-present• Editorial Board, Gastroenterology Research and Practice, 2013-present

Georgios I. Papachristou, MD*Dr. Papachristou oversees a number of institutional studies and multi-center collaborations. He directs a translational research laboratory focusing on the genetic basis, immuonology, and immune therapy of acute pancreatitis. He currently receives research funding from the National Institute of Health, Veterans Affairs Health System, and American College of Gastroenterology. Dr. Papachristou has authored over 100 peer-reviewed articles and book chapters.

Advisory Committee Memberships and Leadership Positions• Director of Endoscopy, Veterans Affairs Health Systems, 2006-present• Colorectal Cancer Prevention Consultant, Pittsburgh Veteran Affairs Health System, 2009-present• Co-Director in Pancreas Research, University of Pittsburgh Medical Center, 2010-present• Treasurer, Collaborative Alliance for Pancreas Research and Education, 2014-present• Member, American College of Gastroenterology Research Committee, 2015-present• President, Collaborative Alliance for Pancreas Education & Research, 2016-present• Named member, NIH SHARP Committee (SpHincterotomy for the Treatment of Acute Recurrent

Pancreatitis), 2017-presentProfessional Affiliations and Society Memberships

• Member, Dutch Digestive Foundation, 2009-presentEditorships

• Reviewer, Pancreas, 2005-present• Reviewer, American Journal of Gastroenterology, 2006-present• Reviewer, Gastrointestinal Endoscopy, 2007-present• Reviewer, Clinical Gastroenterology and Hepatology, 2010-present• Reviewer, Dutch Digestive Foundation, 2010-present• Reviewer, Gastroenterology, 2010-present• Editorial Board, Annals of Gastroenterology, 2010-present

Honors and Awards• Fellow, American Society of Gastrointestinal Endoscopy, 2012-present

Anna Evans Phillips, MDDr. Phillips is interested in mechanisms of fatty acid toxicity in Severe Acute Pancreatitis; perception of pain in Chronic Pancreatitis; and mechanisms of pain processing in Chronic Pancreatitis.

Siobhan Proksell, MDDr. Proksell's research interests include inflammatory bowel disease and patient safety research.

Mordechai Rabinovitz, MDDr. Rabinovitz’s research involves the assessment and treatment of chronic viral hepatitis, focusing on combination therapy for chronic hepatitis C patients. Additional research efforts focus on developing new therapies for non-alcoholic fatty liver disease (NALFD), biological agents for patients with low platelet count undergoing invasive procedures, and new therapies for patients with hepatic encephalopathy.

Editorships• Reviewer, Digestive Diseases and Sciences, 1987-present• Reviewer, Hepatology, 1992-present• Reviewer, Gastroenterology, 1993-present• Reviewer, Mayo Clinic Proceedings, 2003-present

Vikrant P. Rachakonda, MDDr. Rachakonda researches malnutrition and dysregulation of lipid metabolism in chronic liver disease and the role of muscarinic receptors in the regulation of acute and chronic liver injury.

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases, 2010-present• Member, American Gastroenterology Association, 2010-present• Member, American Society of Gastrointestinal Endoscopy, 2010-present

Shari S. Rogal, MD, MPHAs an adjunct assistant professor of medicine, Dr. Rogal brings her extensive, collaborative experience with Transplant Surgery and the VA Healthcare System to the Division of Gastroenterology, Hepatology and

33



others. This research focus incorporates studies on cell proliferation, adhesion, differentiation, invasion, apoptosis, metabolism, and on stem cells in adult, fetal, and embryonic livers.

Stephen J.D. O'Keefe, MBBS, MD, MScDr. O’Keefe performs translational research into the physiological and pathophysiological responses to feeding and nutritional deprivation. He has received NIH R01 grant support for his studies on the physiological effects of feeding in pancreatic enzyme synthesis in humans with and without disease, the optimal feeding in patients with severe acute pancreatitis, and, most recently, the role of diet, the microbiome, and its metabolites in determining colon cancer risk in extreme-risk Alaska Natives, high-risk African Americans (AA), and minimal risk rural South Africans (NA). His pivotal 2015 study in Nature Communications showed that switching the diets of AA and NA (i.e., Americans were given a traditional African diet high in fiber, low in meat and fat, while Africans were given a westernized diet high in meant and fat and low in fiber) led to profound changes in the colonic microbiome and its metabolome and reciprocal changes in colonic mucosal biomarkers of cancer risk within two weeks. This supports the hypothesis that diet drives colon cancer risk and that it is largely preventable by a high fiber diet. Studies are underway in Alaska to determine whether fiber supplementation will annul the health disparity and extreme rates of colon cancer risk and mortality in Alaska Natives. Finally, Dr. O’Keefe is partnering with the University of Stellenbosch in South Africa to direct the African Microbiome Institute to study the ecology of the microbiome through the Faculties of Medicine, Agrisciences, and Plant Biology, with the overarching aim of improving the health of all Africans.

Study Sections• NCI-NIH Study Sections (special interest groups and programs), 2003-present

Advisory Committee Memberships and Leadership Positions• External Advisory Committee, Division of Nutritional Sciences, UIUC, 2015-present

Editorships• Associate Editor, Frontiers in Gastroenterology Physiology and Science, 2010-present• Assistant Editor-in-Chief, World Journal of Gastroenterology, 2011-present• Editorial Board, Gastroenterology Research and Practice, 2013-present

Georgios I. Papachristou, MD*Dr. Papachristou oversees a number of institutional studies and multi-center collaborations. He directs a translational research laboratory focusing on the genetic basis, immuonology, and immune therapy of acute pancreatitis. He currently receives research funding from the National Institute of Health, Veterans Affairs Health System, and American College of Gastroenterology. Dr. Papachristou has authored over 100 peer-reviewed articles and book chapters.

Advisory Committee Memberships and Leadership Positions• Director of Endoscopy, Veterans Affairs Health Systems, 2006-present• Colorectal Cancer Prevention Consultant, Pittsburgh Veteran Affairs Health System, 2009-present• Co-Director in Pancreas Research, University of Pittsburgh Medical Center, 2010-present• Treasurer, Collaborative Alliance for Pancreas Research and Education, 2014-present• Member, American College of Gastroenterology Research Committee, 2015-present• President, Collaborative Alliance for Pancreas Education & Research, 2016-present• Named member, NIH SHARP Committee (SpHincterotomy for the Treatment of Acute Recurrent

Pancreatitis), 2017-presentProfessional Affiliations and Society Memberships

• Member, Dutch Digestive Foundation, 2009-presentEditorships

• Reviewer, Pancreas, 2005-present• Reviewer, American Journal of Gastroenterology, 2006-present• Reviewer, Gastrointestinal Endoscopy, 2007-present• Reviewer, Clinical Gastroenterology and Hepatology, 2010-present• Reviewer, Dutch Digestive Foundation, 2010-present• Reviewer, Gastroenterology, 2010-present• Editorial Board, Annals of Gastroenterology, 2010-present

Honors and Awards• Fellow, American Society of Gastrointestinal Endoscopy, 2012-present

Anna Evans Phillips, MDDr. Phillips is interested in mechanisms of fatty acid toxicity in Severe Acute Pancreatitis; perception of pain in Chronic Pancreatitis; and mechanisms of pain processing in Chronic Pancreatitis.

Siobhan Proksell, MDDr. Proksell's research interests include inflammatory bowel disease and patient safety research.

Mordechai Rabinovitz, MDDr. Rabinovitz’s research involves the assessment and treatment of chronic viral hepatitis, focusing on combination therapy for chronic hepatitis C patients. Additional research efforts focus on developing new therapies for non-alcoholic fatty liver disease (NALFD), biological agents for patients with low platelet count undergoing invasive procedures, and new therapies for patients with hepatic encephalopathy.

Editorships• Reviewer, Digestive Diseases and Sciences, 1987-present• Reviewer, Hepatology, 1992-present• Reviewer, Gastroenterology, 1993-present• Reviewer, Mayo Clinic Proceedings, 2003-present

Vikrant P. Rachakonda, MDDr. Rachakonda researches malnutrition and dysregulation of lipid metabolism in chronic liver disease and the role of muscarinic receptors in the regulation of acute and chronic liver injury.

Professional Affiliations and Society Memberships• Member, American Association for the Study of Liver Diseases, 2010-present• Member, American Gastroenterology Association, 2010-present• Member, American Society of Gastrointestinal Endoscopy, 2010-present

Shari S. Rogal, MD, MPHAs an adjunct assistant professor of medicine, Dr. Rogal brings her extensive, collaborative experience with Transplant Surgery and the VA Healthcare System to the Division of Gastroenterology, Hepatology and

34



Nutrition. Dr. Rogal studies liver transplant outcomes with particular interests in addiction and pain with chronic liver disease patients. She is also interested in the implementation of science to combat health disparities.

Savreet Sarkaria, MDA Clinical Assistant Professor of Medicine, Dr. Sarkaria's research focuses on screening, early detection, and endoscopic therapies for gastrointestinal cancers, including pancreas, bile ducts, gallbladder, esophagus, stomach, and colon, as well as benign pancreaticobiliary diseases and pancreatic cysts.

Marc B. Schwartz, MDAn Assistant Professor of Medicine, Dr. Schwartz's research interests include cost and utilization of IBD care as well as colon cancer in IBD patients.

Advisory Committee Memberships and Leadership Positions• Clinical Director, IBD Center, 2018-present

Professional Affiliations and Society Memberships• Physician Member, Crohn's & Colitis Foundation of America, 2009-present

Obaid S. Shaikh, MDDr. Shaikh researches the progression of end-stage liver disease, treatment of hepatocellular carcinoma, hepatocarcinogenesis and genomic profiling of liver tumors, and allocation models for liver transplantation.

Advisory Committee Memberships and Leadership Positions• Director, Center for Liver Diseases, 2001-present• Member, Clinical Research Committee, American Association for the Study of Liver Diseases,

2007-present• Member, Liver Transplantation and Surgery Committee, American Association for the Study of

Liver Diseases, 2008-presentEditorships

• Editorial Board, Liver Transplantation, 2005-present• Reviewer, American Journal of Gastroenterology, 2007-present• Reviewer, Archives of Internal Medicine, 2007-present• Reviewer, Hepatology, 2007-present• Reviewer, Liver Transplantation, 2007-present• Reviewer, Digestive Diseases & Sciences, 2007-present• Reviewer, Gastroenterology, 2007-present

Honors and Awards• Member, Royal College of Physicians, London (UK)–Fellow (FRCP), 2003-present

Harkirat Singh, MBBSDr. Singh's research interests concentrate on pancreatic and biliary diseases and related advanced procedures to treat these diseases. He is interested in the natural history of acute pancreatitis as well as outcomes in acute pancreatitis. He also conducts research on the management of subepithelial upper GI tract lesions.

Adam Slivka, MD, PhDA Professor of Medicine, Dr. Slivka researches the non-invasive diagnosis of pancreaticobiliary cancer, development and testing of new drugs and devices used during ERCP, and the development of new strategies to treat pancreatitis and pancreatic cancer.

Advisory Committee Memberships and Leadership Positions• Member, Clinical Operations Committee, University of Pittsburgh Physicians (UPP), 1999-present• Advisory Committee Member, Medicine Program Line, 1999-present• Member, Budget and Financial Planning Committee, American Society for Gastrointestinal

Endoscopy, 1999-present• Member, Compliance Advisory Committee, University of Pittsburgh Physicians (UPP), 1999-

present• Member, Surgical/Interventional/Trauma/Transplant Subcommittee, UPMC Technology

Assessment Committee, 2002-present• Associate Chief, Clinical Affairs, 2003-present

Editorships• Reviewer, Endoscopy, 1994-present• Reviewer, Gastroenterology, 1994-present• Reviewer, New England Journal of Medicine, 1994-present• Editorial Review Board, Gastroenterology, 1996-present• Reviewer, American Journal of Gastroenterology, 1996-present• Reviewer, Gastrointestinal Endoscopy, 1999-present• Section Editor, Up to Date, 2006-present• Editorial Review Board, Gastrointestinal Endoscopy, 2007-present


Eva M Szigethy, MD, PhDDr. Szigethy's research involves cognitive behavioral therapy to improve health care delivery for adult and pediatric GI patients, using psychotherapy, hypnosis, digital behavioral tools, and pharmacotherapy. Dr. Szigethy's additional research interests include advanced programming for IBD patients and patients experiencing chronic pain, an interest in narcotic bowel syndrome and the mechanisms underlying this type of central hyperalgesia, as well as treatments to manage pain and opioid detoxification. Dr. Szigethy is the principal investigator of a recently awarded PCORI contract which explores advanced technology systems designed to manage chronic disease and will compare a technology-centric approach with a team-based, high-touch intervention. This study takes place within three IBD specialty medical homes at renowned hospitals, with UPMC as the lead site.

David C. Whitcomb, MD, PhDDr. Whitcomb’s research program involves a pancreatic disease focus for modeling complex, multistep gene-environment interactive disorders requiring a precision medicine approach. Dr. Whitcomb's multicenter comprises research on genotype-phenotyping hereditary pancreatitis as well as North American Pancreatitis Study II (NAPS2) programs. It also includes studies on acute pancreatitis and pancreatic cancer, using reverse engineering and predictive modeling approaches. Dr. Whitcomb leads the Genomic Resource to Enhance

35



Nutrition. Dr. Rogal studies liver transplant outcomes with particular interests in addiction and pain with chronic liver disease patients. She is also interested in the implementation of science to combat health disparities.

Savreet Sarkaria, MDA Clinical Assistant Professor of Medicine, Dr. Sarkaria's research focuses on screening, early detection, and endoscopic therapies for gastrointestinal cancers, including pancreas, bile ducts, gallbladder, esophagus, stomach, and colon, as well as benign pancreaticobiliary diseases and pancreatic cysts.

Marc B. Schwartz, MDAn Assistant Professor of Medicine, Dr. Schwartz's research interests include cost and utilization of IBD care as well as colon cancer in IBD patients.

Advisory Committee Memberships and Leadership Positions• Clinical Director, IBD Center, 2018-present

Professional Affiliations and Society Memberships• Physician Member, Crohn's & Colitis Foundation of America, 2009-present

Obaid S. Shaikh, MDDr. Shaikh researches the progression of end-stage liver disease, treatment of hepatocellular carcinoma, hepatocarcinogenesis and genomic profiling of liver tumors, and allocation models for liver transplantation.

Advisory Committee Memberships and Leadership Positions• Director, Center for Liver Diseases, 2001-present• Member, Clinical Research Committee, American Association for the Study of Liver Diseases,

2007-present• Member, Liver Transplantation and Surgery Committee, American Association for the Study of

Liver Diseases, 2008-presentEditorships

• Editorial Board, Liver Transplantation, 2005-present• Reviewer, American Journal of Gastroenterology, 2007-present• Reviewer, Archives of Internal Medicine, 2007-present• Reviewer, Hepatology, 2007-present• Reviewer, Liver Transplantation, 2007-present• Reviewer, Digestive Diseases & Sciences, 2007-present• Reviewer, Gastroenterology, 2007-present

Honors and Awards• Member, Royal College of Physicians, London (UK)–Fellow (FRCP), 2003-present

Harkirat Singh, MBBSDr. Singh's research interests concentrate on pancreatic and biliary diseases and related advanced procedures to treat these diseases. He is interested in the natural history of acute pancreatitis as well as outcomes in acute pancreatitis. He also conducts research on the management of subepithelial upper GI tract lesions.

Adam Slivka, MD, PhDA Professor of Medicine, Dr. Slivka researches the non-invasive diagnosis of pancreaticobiliary cancer, development and testing of new drugs and devices used during ERCP, and the development of new strategies to treat pancreatitis and pancreatic cancer.

Advisory Committee Memberships and Leadership Positions• Member, Clinical Operations Committee, University of Pittsburgh Physicians (UPP), 1999-present• Advisory Committee Member, Medicine Program Line, 1999-present• Member, Budget and Financial Planning Committee, American Society for Gastrointestinal

Endoscopy, 1999-present• Member, Compliance Advisory Committee, University of Pittsburgh Physicians (UPP), 1999-

present• Member, Surgical/Interventional/Trauma/Transplant Subcommittee, UPMC Technology

Assessment Committee, 2002-present• Associate Chief, Clinical Affairs, 2003-present

Editorships• Reviewer, Endoscopy, 1994-present• Reviewer, Gastroenterology, 1994-present• Reviewer, New England Journal of Medicine, 1994-present• Editorial Review Board, Gastroenterology, 1996-present• Reviewer, American Journal of Gastroenterology, 1996-present• Reviewer, Gastrointestinal Endoscopy, 1999-present• Section Editor, Up to Date, 2006-present• Editorial Review Board, Gastrointestinal Endoscopy, 2007-present


Eva M Szigethy, MD, PhDDr. Szigethy's research involves cognitive behavioral therapy to improve health care delivery for adult and pediatric GI patients, using psychotherapy, hypnosis, digital behavioral tools, and pharmacotherapy. Dr. Szigethy's additional research interests include advanced programming for IBD patients and patients experiencing chronic pain, an interest in narcotic bowel syndrome and the mechanisms underlying this type of central hyperalgesia, as well as treatments to manage pain and opioid detoxification. Dr. Szigethy is the principal investigator of a recently awarded PCORI contract which explores advanced technology systems designed to manage chronic disease and will compare a technology-centric approach with a team-based, high-touch intervention. This study takes place within three IBD specialty medical homes at renowned hospitals, with UPMC as the lead site.

David C. Whitcomb, MD, PhDDr. Whitcomb’s research program involves a pancreatic disease focus for modeling complex, multistep gene-environment interactive disorders requiring a precision medicine approach. Dr. Whitcomb's multicenter comprises research on genotype-phenotyping hereditary pancreatitis as well as North American Pancreatitis Study II (NAPS2) programs. It also includes studies on acute pancreatitis and pancreatic cancer, using reverse engineering and predictive modeling approaches. Dr. Whitcomb leads the Genomic Resource to Enhance

36



Available Therapy (GREAT) study, which seeks to initiate the delivery of precision medicine for complex chronic disorders and their complications. He also studies the pathophysiology of severe acute pancreatitis and pain genetics.

Advisory Committee Memberships and Leadership Positions• Committee Member, National Pancreas Foundation, 2007-present

Professional Affiliations and Society Memberships• Member, American Gastroenterological Association, 1992-present• Member, American College of Gastroenterology, 1996-present• Member, International Association of Pancreatology, 2000-present• Member, American Pancreatic Association, 2000-present• Member, European Pancreas Club, 2002-present• Director, Gastroenterology T32 Training Program, 2003-present• Founder/Member, Collaborative Alliance for Pancreatic Education and Research, 2012-present• Director, PancreasFest, Pittsburgh, 2016-present

Editorships• Editorial Board, Nature Reviews: Gastroenterology and Hepatology, 2007-present• Section Editor, Current Treatment Options in Gastroenterology, 2007-present• Editorial Board, American Journal Physiology: Gastrointestinal and Liver Physiology, 2007-present• Editorial Board, Pancreatology, 2007-present• Editorial Board, Pancreas, 2007-present• Associate Editor, Pancreas, Pancreatology and Digestive Disease and Science, 2007-present• Peer Reviewer, Multiple journals, (Alimentary Pharmacology and Therapeutics, American Journal of

Gastroenterology, American Journal of Pathology, American Journal of Physiology-Gastroenterology, American Journal of Physiology-Regulatory Integrative and Comparative Physiology), 2007-present

• Editor-in-Chief, Clinical and Translational Gastroenterology, 2016-present Honors and Awards

• Member, American Society for Clinical Investigators, 2000-present• Endowed Chair, Giant Eagle Foundation Professor of Cancer Genetics, 2006-present

Dhiraj Yadav, MD, MPHDr. Yadav studies the epidemiology of pancreatic diseases, using local, state, and national level data as well as collaborative studies to define its various aspects. His major contributions to the scientific literature include the role of alcohol and tobacco; incidence, prevalence, and hospitalizations; risk and burden of readmissions; and the natural history of pancreatitis. Data generated from his studies are often used by national agencies, such as the National Institutes of Health, to set research priorities. Dr. Yadav is a member of the NIDDK-funded NAPS consortium, which has prospectively ascertained the nation's largest prospective cohort of patients with recurrent acute and chronic pancreatitis. He is the Co-PI for the NIDDK/NCI-funded Pittsburgh Clinical Center, which is part of the Consortium to study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC). He co-chairs the adult chronic pancreatitis working group for the consortium and is Co-PI of the longitudinal cohort study of chronic pancreatitis (The PROCEED Study). Dr. Yadav is also the Co-PI of an NIDDK planning grant to develop a multicenter randomized clinical trial of minor papilla sphincterotomy in patients with acute recurrent pancreatitis with pancreas divisum (The SHARP Trial). He is frequently invited to national and international conferences and seminars to discuss his research. He has also

participated in American Pancreatic Association's and Pancreas Fest's development of consensus and practice guidelines for different aspects of pancreatitis.

Study Sections• Research Review Panel, American Gastroenterological Association, 2014-present

Advisory Committee Memberships and Leadership Positions• Member, Scientific Advisory Committee, Montefiore University Hospital, Clinical and Translational

Research Center, UPMC, 2007-present• Member, Collaborative Alliance for Pancreatic Education and Research, 2010-present• Member, Steering Committee for the NPF Registry, National Pancreas Foundation, 2015-present• Member, NIH SHARP Committee, 2017-present

Professional Affiliations and Society Memberships• Member, American College of Gastroenterology, 1998-present• Member, Mayo Clinic Alumni Association, 2002-present• Member, American Pancreatic Association, 2003-present• Member, American Gastroenterological Association, 2005-present

Editorships• Reviewer, Multiple journals (Journal of Gastroenterology and Hepatology, Pancreatology, Nutrition

and Cancer, Pancreas), 2007-present• Editorial Board, Pancreas, 2013-present• Editorial Board, Pancreatology, 2014-present

Honors and Awards• Fellow, American Gastroenterological Association, 2014-present


37



Available Therapy (GREAT) study, which seeks to initiate the delivery of precision medicine for complex chronic disorders and their complications. He also studies the pathophysiology of severe acute pancreatitis and pain genetics.

Advisory Committee Memberships and Leadership Positions• Committee Member, National Pancreas Foundation, 2007-present

Professional Affiliations and Society Memberships• Member, American Gastroenterological Association, 1992-present• Member, American College of Gastroenterology, 1996-present• Member, International Association of Pancreatology, 2000-present• Member, American Pancreatic Association, 2000-present• Member, European Pancreas Club, 2002-present• Director, Gastroenterology T32 Training Program, 2003-present• Founder/Member, Collaborative Alliance for Pancreatic Education and Research, 2012-present• Director, PancreasFest, Pittsburgh, 2016-present

Editorships• Editorial Board, Nature Reviews: Gastroenterology and Hepatology, 2007-present• Section Editor, Current Treatment Options in Gastroenterology, 2007-present• Editorial Board, American Journal Physiology: Gastrointestinal and Liver Physiology, 2007-present• Editorial Board, Pancreatology, 2007-present• Editorial Board, Pancreas, 2007-present• Associate Editor, Pancreas, Pancreatology and Digestive Disease and Science, 2007-present• Peer Reviewer, Multiple journals, (Alimentary Pharmacology and Therapeutics, American Journal of

Gastroenterology, American Journal of Pathology, American Journal of Physiology-Gastroenterology, American Journal of Physiology-Regulatory Integrative and Comparative Physiology), 2007-present

• Editor-in-Chief, Clinical and Translational Gastroenterology, 2016-present Honors and Awards

• Member, American Society for Clinical Investigators, 2000-present• Endowed Chair, Giant Eagle Foundation Professor of Cancer Genetics, 2006-present

Dhiraj Yadav, MD, MPHDr. Yadav studies the epidemiology of pancreatic diseases, using local, state, and national level data as well as collaborative studies to define its various aspects. His major contributions to the scientific literature include the role of alcohol and tobacco; incidence, prevalence, and hospitalizations; risk and burden of readmissions; and the natural history of pancreatitis. Data generated from his studies are often used by national agencies, such as the National Institutes of Health, to set research priorities. Dr. Yadav is a member of the NIDDK-funded NAPS consortium, which has prospectively ascertained the nation's largest prospective cohort of patients with recurrent acute and chronic pancreatitis. He is the Co-PI for the NIDDK/NCI-funded Pittsburgh Clinical Center, which is part of the Consortium to study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC). He co-chairs the adult chronic pancreatitis working group for the consortium and is Co-PI of the longitudinal cohort study of chronic pancreatitis (The PROCEED Study). Dr. Yadav is also the Co-PI of an NIDDK planning grant to develop a multicenter randomized clinical trial of minor papilla sphincterotomy in patients with acute recurrent pancreatitis with pancreas divisum (The SHARP Trial). He is frequently invited to national and international conferences and seminars to discuss his research. He has also

participated in American Pancreatic Association's and Pancreas Fest's development of consensus and practice guidelines for different aspects of pancreatitis.

Study Sections• Research Review Panel, American Gastroenterological Association, 2014-present

Advisory Committee Memberships and Leadership Positions• Member, Scientific Advisory Committee, Montefiore University Hospital, Clinical and Translational

Research Center, UPMC, 2007-present• Member, Collaborative Alliance for Pancreatic Education and Research, 2010-present• Member, Steering Committee for the NPF Registry, National Pancreas Foundation, 2015-present• Member, NIH SHARP Committee, 2017-present

Professional Affiliations and Society Memberships• Member, American College of Gastroenterology, 1998-present• Member, Mayo Clinic Alumni Association, 2002-present• Member, American Pancreatic Association, 2003-present• Member, American Gastroenterological Association, 2005-present

Editorships• Reviewer, Multiple journals (Journal of Gastroenterology and Hepatology, Pancreatology, Nutrition

and Cancer, Pancreas), 2007-present• Editorial Board, Pancreas, 2013-present• Editorial Board, Pancreatology, 2014-present

Honors and Awards• Fellow, American Gastroenterological Association, 2014-present


38



TEACHING ACTIVITIES

In FY19, the Division’s Gastroenterology Fellowship Program enjoyed a full complement of 17 gastroenterology fellows. More than400 candidates applied for admission in FY19, with approximately 40 interviewed and five selected. The Division’s accredited FY19 Gastroenterology Fellowship Program was led by Kenneth Fasanella, MD, program director, and Rohit Das, MD, associate program director while its accredited FY19 Transplant Hepatology Advanced Fellowship Program was led by Shahid Malik, MD.

For the past ten years, the Division of Gastroenterology, Hepatology and Nutrition has also managed a successful T32 training grant with research trainees. Based on the translational research strengths of the Division and its commitment to complex disease interactions and treatments, the focus of the Division’s T32 program centers on big data and precision medicine in gastroenterology and hepatology. Under the leadership of David Whitcomb, MD, PhD, and David Binion, MD, this T32 leverages the Division’s successful U01 programs to allow T32 trainees the ability to integrate the tools of big data and personalized medicine into clinical and translational research and team teaching.

Divisional leadership also facilitated with medical student teaching, with Siobhan Proksell, MD, serving as co-course director of the School of Medicine’s Second Year Medical School GI Course, with the help of Gavin Arteel, PhD, Michael Laundau, MD (Pathology), and Kenneth Lee, MD (Surgery). FY19 is Dr. Proksell’s first directorship year, and she is working diligently to revamp, revise, and update the course. Additionally, through his Laboratory of Educational Technology, James B. McGee, MD, continues to explore and address the changing educational expectations of students and the utilization of innovative, technological teaching approaches in the School of Medicine.

This past year, the Division hosted several education conferences. The accredited and international PancreasFest 2018 conference was held at the Sheraton Station Square Hotel in Pittsburgh in July 2018. This annual pancreas research and clinical conference features lectures and discussion groups mixed with investigative research meetings to further the multidisciplinary understanding and treatment of pancreatic diseases. This year’s course directors included Nathan Bahary, MD, PhD; Randall E. Brand, MD; Sohail Husain, MD; Georgios I. Papachristou, MD, PhD; David C. Whitcomb, MD, PhD; and Herbert J. Zeh, MD.

Attendance was excellent at 240 domestic and international pancreatologists and related medicalprofessionals. The Division also manages the accredited,semi-annual IBD Collaborative program in collaboration with the Allegheny Health Network. Designed to discussadvanced Inflammatory Bowel Disease (IBD) treatments and procedures, welcomes attendance from all academic and community gastroenterologists within the Greater Pittsburgh region and includes didactic lectures and case presentations. This fiscal year’s programs occurred at the Rivers Club in September 2018 and February 2019, co-directed by Marc Schwartz, MD (UPMC), and Sandra El-

I n F Y 1 9 , t h e G I D i v i s i o n r e c e i v e d m o r e t h a n

4005 positions

in i ts c l in ica l fe l lowship programs

applicationscompet ing for on ly

Hachem, MD (AHN). The Pittsburgh Gut Club, directed by Robert Schoen, MD, MPH, in 2018-2019, is an accredited lecture series for regional gastroenterologists. Two guest speakers presented in FY19, and attendance numbered approximately 75 physicians per session, many of whom were physicians in practice in the surrounding community. FY19 Pittsburgh Gut Club Speakers included: Reem Sharaiha, MD, MSc, from Weill Cornell Medicine and Fasiha Kanwal, MD, MSHS, from Baylor. Maria Abreu, MDwill speak as part of this year’s series in September 2019. All Gut Club speakers also serve as visiting professors within the Division. Additionally, preliminary planning for an inaugural, annual, accredited hepatology conference began in FY19, which will be directed by Ramon Bataller, MD, PhD.

The Division also holds several weekly conferences throughout the year, providing trainees and faculty alike with numerous opportunities to expand their clinical and research knowledge. Clinical conferences included: GI Grand Rounds (course director: Kenneth Fasanella, MD), which featured lectures by external and internal faculty, as well as case presentations from clinical fellows; Hepatology Rounds (course director: Shahid Malik, MD), with lectures focused on hepatology medicine; Advanced Endoscopy/Pancreaticobiliary Conference (course director: Dhiraj Yadav, MD, MPH), which provides a weekly discussion of ERCP, EUS, and related GI procedure cases; IBD LIVE (Course director: Miguel Regueiro, MD (Cleveland Clinic); Site director: David Binion, MD), a weekly online interactive conference with IBD case discussions among more than 15 East Cost academic IBD programs; and the State of the Art (SOTA) Lecture Series (Course director: Randall Brand, MD), a didactic lecture series where faculty experts discuss key areas of gastroenterology and hepatology medicine. Research conferences, focused more on basic and translational research and fellow training, included GI Research Rounds (Course director: Yang Liu, PhD); the Tuesday Educational Series for GI Fellows (Course coordinator: Dhiraj Yadav, MD, MPH); and the Endoscopy Conference (Course coordinator: Robert E. Schoen, MD, MPH). In April 2019, as the recipient of a generous donation from the Gerson family for the annual Sadie Gerson Distinguished Scholar Award, Robert E. Schoen, MD, MPH, invited Chyke Doubeni, MD, MPH, from the Perelman School of Medicine at the University of Pennsylvania to discuss “Eliminating Preventable Death from Colorectal Cancer by Addressing Modifiable Failures of Screening” at Medical Grand Rounds. Dr. Doubeni met with the Department of Family Medicine, various division attendings, and GI Fellows. The Division also welcomed the following visiting professors in FY19: Suresh T. Chari, MD, Professor of Medicine in the Department of Gastroenterology at Mayo Clinic, Rochester, MN (February 5-7, 2019); and Aida Habtezion, MD, MSc, an Associate Professor of Medicine and Ballinger-Swindells Endowed Scholar in the Division of Gastroenterology and Hepatology at Stanford University, Stanford, CA (March 20-21, 2019).

Moreover, the Division frequently engages with the broader Pittsburgh community, and as part of its outreach, the Division also hosts IBD UNITE (Unify, Network, Inspire, Treat, & Educate), an annual IBD patient program. This year’s event was attended by over 230 patients and loved ones and led by Helen Sysko, PhD.

With the majority of Division faculty serving as keynote course faculty for accredited physician educational

PancreasFest 2018 welcomed over 200 pandreatologists from around the world to discuss recent medical advances in the treatment of pancreatic diseases.

39



TEACHING ACTIVITIES

In FY19, the Division’s Gastroenterology Fellowship Program enjoyed a full complement of 17 gastroenterology fellows. More than 400 candidates applied for admission in FY19, with approximately 40 interviewed and five selected. The Division’s accredited FY19 Gastroenterology Fellowship Program was led by Kenneth Fasanella, MD, program director, and Rohit Das, MD, associate program director while its accredited FY19 Transplant Hepatology Advanced Fellowship Program was led by Shahid Malik, MD.

For the past ten years, the Division of Gastroenterology, Hepatology and Nutrition has also managed a successful T32 training grant with research trainees. Based on the translational research strengths of the Division and its commitment to complex disease interactions and treatments, the focus of the Division’s T32 program centers on big data and precision medicine in gastroenterology and hepatology. Under the leadership of David Whitcomb, MD, PhD, and David Binion, MD, this T32 leverages the Division’s successful U01 programs to allow T32 trainees the ability to integrate the tools of big data and personalized medicine into clinical and translational research and team teaching.

Divisional leadership also facilitated with medical student teaching, with Siobhan Proksell, MD, serving as co-course director of the School of Medicine’s Second Year Medical School GI Course, with the help of Gavin Arteel, PhD, Michael Laundau, MD (Pathology), and Kenneth Lee, MD (Surgery). FY19 is Dr. Proksell’s first directorship year, and she is working diligently to revamp, revise, and update the course. Additionally, through his Laboratory of Educational Technology, James B. McGee, MD, continues to explore and address the changing educational expectations of students and the utilization of innovative, technological teaching approaches in the School of Medicine.

This past year, the Division hosted several education conferences. The accredited and international PancreasFest 2018 conference was held at the Sheraton Station Square Hotel in Pittsburgh in July 2018. This annual pancreas research and clinical conference features lectures and discussion groups mixed with investigative research meetings to further the multidisciplinary understanding and treatment of pancreatic diseases. This year’s course directors included Nathan Bahary, MD, PhD; Randall E. Brand, MD; Sohail Husain, MD; Georgios I. Papachristou, MD, PhD; David C. Whitcomb, MD, PhD; and Herbert J. Zeh, MD.

Attendance was excellent at 240 domestic and international pancreatologists and related medical professionals. The Division also manages the accredited, semi-annual IBD Collaborative program in collaboration with the Allegheny Health Network. Designed to discuss advanced Inflammatory Bowel Disease (IBD) treatments and procedures, welcomes attendance from all academic and community gastroenterologists within the Greater Pittsburgh region and includes didactic lectures and case presentations. This fiscal year’s programs occurred at the Rivers Club in September 2018 and February 2019, co-directed by Marc Schwartz, MD (UPMC), and Sandra El-

I n F Y 1 9 , t h e G I D i v i s i o n r e c e i v e d m o r e t h a n

4005 positions

in i ts c l in ica l fe l lowship programs

applicationscompet ing for on ly

Hachem, MD (AHN). The Pittsburgh Gut Club, directed by Robert Schoen, MD, MPH, in 2018-2019, is an accredited lecture series for regional gastroenterologists. Two guest speakers presented in FY19, and attendance numbered approximately 75 physicians per session, many of whom were physicians in practice in the surrounding community. FY19 Pittsburgh Gut Club Speakers included: Reem Sharaiha, MD, MSc, from Weill Cornell Medicine and Fasiha Kanwal, MD, MSHS, from Baylor. Maria Abreu, MD will speak as part of this year’s series in September 2019. All Gut Club speakers also serve as visiting professors within the Division. Additionally, preliminary planning for an inaugural, annual, accredited hepatology conference began in FY19, which will be directed by Ramon Bataller, MD, PhD.

The Division also holds several weekly conferences throughout the year, providing trainees and faculty alike with numerous opportunities to expand their clinical and research knowledge. Clinical conferences included: GI Grand Rounds (course director: Kenneth Fasanella, MD), which featured lectures by external and internal faculty, as well as case presentations from clinical fellows; Hepatology Rounds (course director: Shahid Malik, MD), with lectures focused on hepatology medicine; Advanced Endoscopy/PancreaticobiliaryConference (course director: Dhiraj Yadav, MD, MPH), which provides a weekly discussion of ERCP, EUS, and related GI procedure cases; IBD LIVE (Course director: Miguel Regueiro, MD (Cleveland Clinic); Site director: David Binion, MD), a weekly online interactive conference with IBD case discussions among more than 15 East Cost academic IBD programs; and the State of the Art (SOTA) Lecture Series (Course director: Randall Brand, MD), a didactic lecture series where faculty experts discuss key areas of gastroenterology and hepatology medicine. Research conferences, focused more on basic and translational research and fellow training, included GI Research Rounds (Course director: Yang Liu, PhD); the Tuesday Educational Series forGI Fellows (Course coordinator: Dhiraj Yadav, MD, MPH); and the Endoscopy Conference (Course coordinator: Robert E. Schoen, MD, MPH). In April 2019, as the recipient of a generous donation from the Gerson family for the annual Sadie Gerson Distinguished Scholar Award, Robert E. Schoen, MD, MPH, invited Chyke Doubeni, MD, MPH, from the Perelman School of Medicine at the University of Pennsylvania to discuss “Eliminating Preventable Death from Colorectal Cancer by Addressing Modifiable Failures of Screening” at Medical Grand Rounds. Dr. Doubeni met with the Department of Family Medicine, various division attendings, and GI Fellows. The Division also welcomed the following visiting professors in FY19: Suresh T. Chari, MD, Professor of Medicine in the Department of Gastroenterology at Mayo Clinic, Rochester, MN (February 5-7, 2019); and Aida Habtezion, MD, MSc, an Associate Professor of Medicine and Ballinger-Swindells Endowed Scholar in the Division of Gastroenterology and Hepatology at Stanford University, Stanford, CA (March 20-21, 2019).

Moreover, the Division frequently engages with the broader Pittsburgh community, and as part of its outreach, the Division also hosts IBD UNITE (Unify, Network, Inspire, Treat, & Educate), an annual IBD patient program. This year’s event was attended by over 230 patients and loved ones and led by Helen Sysko, PhD.

With the majority of Division faculty serving as keynote course faculty for accredited physician educational

PancreasFest 2018 welcomed over 200 pandreatologists from around the world to discuss recent medical advances in the treatment of pancreatic diseases.

40



and research meetings throughout the world, the Division of Gastroenterology, Hepatology, and Nutrition continues to emphasis education and training.

Teaching Awards and HonorsSeveral faculty were recognized this year for their commitment to education:

• James B. McGee, MD, received the Carnegie Teaching Award from the CarnegieScience Center in July 2018.

• Howard Dubner, MD, received the UPMC Gastroenterology and Hepatology TeachingAward at this year’s Fellows’ Graduation in June.

Clinical Fellows, FY2019

Current FellowsCatherine Bartnik, MDMedical School: University of MichiganResidency: Emory Healthcare

Weston Bettner, MDMedical School: Temple UniversityResidency: Johns Hopkins Hospital

Hui-Wei (Doris) Chen, MDMedical School: University of PittsburghResidency: University of Pittsburgh Medical Center

Debbie Cheng, MDMedical School: University of MichiganResidency: University of Pittsburgh Medical Center

Adam Gluskin, MDMedical School: University of Illinois at ChicagoResidency: Northwestern Memorial Hospital

Rory Grace, MDMedical School: George Washington UniversityResidency: University of Pennsylvania Health System

Ru Min Lee, MDMedical School: University of Melbourne, AustraliaResidency: University of Pennsylvania Health System

Akshata Moghe, MD, PhD Medical School: Seth G.S. Medical College, Mumbai, IndiaResidency: University of Pittsburgh Medical Center

This year’s current fellows in the Division of Gastroenterology, Hepatology and Nutrition.

Kohtaro (Cody) Ooka, MD Medical School: Icahn School of Medicine at Mount SinaiResidency: Yale New Haven Medical Center

Stephanie Romutis, MDMedical School: Wake Forest UniversityResidency: Boston Medical Center

Ajay Singhvi, MDMedical School: Feinberg School of Medicine, Northwestern UniversityResidency: Northwestern Memorial Hospital

Kishore Vipperla, MDMedical School: Osmania Medical CollegeResidency: St. Luke’s University Hospital

Departing FellowsJeffrey Dueker, MD Chief Gastroenterology FellowMedical School: Saint Louis UniversityResidency: Oregon Health and Sciences UniversityCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Mohannad Dugum, MD Advanced Endoscopy FellowMedical School: Jordan University of Science & TechnologyResidency: Cleveland ClinicCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Hakirat Singh, MD Advanced Endoscopy FellowMedical School: All India Institute of Medical SciencesResidency: Thomas Jefferson University HospitalsCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Diana Jaiyeola, MDMedical School: University of PennsylavaniaResidency: Northwestern Memorial HospitalCurrent Position: Gastroenterologist, St. Luke’s University Health Network, Bethlehem, PA

Matthew Klinge, MD Hepatology FellowMedical School: Jefferson Medical CollegeResidency: University of Pittsburgh Medical CenterCurrent Position: Gastroenterologist, UPMC Erie - Gastroenterology (Bayfront)

Bassem Matta, MDMedical School: American University of Beirut

41



and research meetings throughout the world, the Division of Gastroenterology, Hepatology, and Nutrition continues to emphasis education and training.

Teaching Awards and HonorsSeveral faculty were recognized this year for their commitment to education:

• James B. McGee, MD, received the Carnegie Teaching Award from the Carnegie Science Center in July 2018.

• Howard Dubner, MD, received the UPMC Gastroenterology and Hepatology Teaching Award at this year’s Fellows’ Graduation in June.

Clinical Fellows, FY2019

Current FellowsCatherine Bartnik, MDMedical School: University of MichiganResidency: Emory Healthcare

Weston Bettner, MDMedical School: Temple UniversityResidency: Johns Hopkins Hospital

Hui-Wei (Doris) Chen, MDMedical School: University of PittsburghResidency: University of Pittsburgh Medical Center

Debbie Cheng, MDMedical School: University of MichiganResidency: University of Pittsburgh Medical Center

Adam Gluskin, MDMedical School: University of Illinois at ChicagoResidency: Northwestern Memorial Hospital

Rory Grace, MDMedical School: George Washington UniversityResidency: University of Pennsylvania Health System

Ru Min Lee, MDMedical School: University of Melbourne, AustraliaResidency: University of Pennsylvania Health System

Akshata Moghe, MD, PhD Medical School: Seth G.S. Medical College, Mumbai, IndiaResidency: University of Pittsburgh Medical Center

This year’s current fellows in the Division of Gastroenterology, Hepatology and Nutrition.

Kohtaro (Cody) Ooka, MD Medical School: Icahn School of Medicine at Mount SinaiResidency: Yale New Haven Medical Center

Stephanie Romutis, MDMedical School: Wake Forest UniversityResidency: Boston Medical Center

Ajay Singhvi, MDMedical School: Feinberg School of Medicine, Northwestern UniversityResidency: Northwestern Memorial Hospital

Kishore Vipperla, MDMedical School: Osmania Medical CollegeResidency: St. Luke’s University Hospital

Departing FellowsJeffrey Dueker, MD Chief Gastroenterology FellowMedical School: Saint Louis UniversityResidency: Oregon Health and Sciences UniversityCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Mohannad Dugum, MD Advanced Endoscopy FellowMedical School: Jordan University of Science & TechnologyResidency: Cleveland ClinicCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Hakirat Singh, MD Advanced Endoscopy FellowMedical School: All India Institute of Medical SciencesResidency: Thomas Jefferson University HospitalsCurrent Position: Assistant Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Diana Jaiyeola, MDMedical School: University of PennsylavaniaResidency: Northwestern Memorial HospitalCurrent Position: Gastroenterologist, St. Luke’s University Health Network, Bethlehem, PA

Matthew Klinge, MD Hepatology FellowMedical School: Jefferson Medical CollegeResidency: University of Pittsburgh Medical CenterCurrent Position: Gastroenterologist, UPMC Erie - Gastroenterology (Bayfront)

Bassem Matta, MDMedical School: American University of Beirut

42



• Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of bacterial exposure to the endoscopist's face during endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Presentations and Abstracts• “Reduction of Opiate Use ad Depression with an IBD Medical Home Care Model,” Department of

Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019• “Performance of the Veteran’s Choice Program in Veterans Referred for Colonoscopy,” DDW

2019, San Diego, CA, May 2019• “Colonoscopy Volume of Colonic Irrigation (VOCI) and Rate of Adequate Bowel Prep and

Adenomas per Colonoscopy,” DDW 2019, San Diego, CA, May 2019• “Rate of Inappropriate FIT Testing at a VA Healthcare System,” DDW 2019, San Diego, CA, May

2019Awards

• First Place Research Award, Performance of the Veterans Choice Program for Colonoscopy Referrals at a Tertiary VA Center, VA Pittsburgh Healthcare System’s 2019 Research Week, Pittsburgh, PA, May 2019

• Named Team Member, Selected to name the best IBD research abstracts at DDW 2019, DDW 2019, San Diego, CA, May 2019

Mohannad Dugum, MDPublications

• Kakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-Related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-1363.

• Glass D, Huang DT, Dugum M, Chintamaneni P, Cua S, Saul M, Marsh W, Al-Khafaji A. Rectal Trumpet-Associated Hemorrhage in the Intensive Care Unit: A Quality Improvement Initiative. J Wound Ostomy Continence Nurs. 2018 Nov/Dec;45(6):516-520.

• Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severity of Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Adam Gluskin, MDPublications

• Keswani RN, Benson M, Beveridge C, Gawron AJ, Gluskin AB, Kahi CJ, Kaltenbach TR, McClure J, Schenck R, Yadlapati RH, Duloy A. Colonoscopy-Naïve Raters Can Be Trained to Assess Colonoscopy Quality. Clin Gastroenterol Hepatol. 2019 Jun 20. Epub ahead of print]

• Yadlapati R, Johnston ER, Gluskin AB, Gregory DL, Cyrus R, Werth L, Ciolino JD, Grande DP, Keswani RN. An automated inpatient split dose bowel preparation improves colonoscopy quality and reduces repeat procedures. J Clin Gasteroenterol 2018;52(8):709-14.

Presentations and Abstracts• “Rate of inappropriate FIT testing at a VA health care system,” DDW 2019, San Diego, CA, May

2019• “The quality of early acute pancreatitis management has improved minimally over time,” DDW

2019, San Diego, CA, May 2019• “Admitting actue pancreatitis patietns who require intensive care to the floor is common and

Residency: Duke University HospitalCurrent Position: Advanced Endoscopy Fellow, NYU Langone Health

R. Warren Sands, MD, PhDMedical School: Northwestern UniversityResidency: University of Pittsburgh Medical CenterCurrent Position: Hepatology Fellow, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Fellow ActivitiesCatherine Bartnik, MD

Publications• Bartnik CM, Maheshwari RN, Subramanian RM. Beating the Odds: A Full-Term Delivery After Liver

Transplantation of a Pregnant Hyperthyroid Patient at 19 Weeks' Gestation for Propylthiouracil-Induced Acute Liver Failure. Transplant Proc. 2018 Dec;50(10):3995-3999.

Weston Bettner, MDPresentations and Abstracts

• Can We Develop Precision Medicine for Biologic Selection in IBD Based on Routinely AvailableClinical Information? Using Big Data Analytics to Identify Predictors of Anti-TNF Response, ACG2018 Annual Scientific Meeting, Philadelphia, PA, 10/1/2018

• Peripheral blood eosinophilia functions as a candidate biomarker of decreased response to anti-TNF therapy in Crohn’s disease, DDW 2019, San Diego, CA, 5/1/2019

Hui-Wei (Doris) Chen, MDPublications

• Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Sood P, Rachakonda V, Dunn MA,Tevar AD. Gait Speed and Grip Strength are associated with Dropping Out of the Liver TransplantWaiting List. Transplant Proc. 2019 Apr;51(3):794-97.

• Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M,Lai JC. Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Man Undergoing UrgentEvaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

Presentations and Abstracts• “A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve

Physical Function in Patients with Advanced Liver Disease,” American Transplant Congress,Boston, MA, June 2019

• “A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to ImprovePhysical Function in Patients with Advanced Liver Disease,” Department of Medicine ResearchDay, University of Pittsburgh, Pittsburgh, PA, April 2019

Jeffrey Dueker, MDPublications

• Dueker JM, Luty J, Perry DJ, Izumi S, Fromme EK, and DiVeronica M. A Resident-Led Initiative toIncrease Documentation of Surrogate Decision Makers for Hospitalized Patients. J Grad MedEduc. 2019 Jun;11(3):295-300.

43



• Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M,Papachristou GI, Kreiss C, Khalid A. Risk of bacterial exposure to the endoscopist's face duringendoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Presentations and Abstracts• “Reduction of Opiate Use ad Depression with an IBD Medical Home Care Model,” Department of

Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019• “Performance of the Veteran’s Choice Program in Veterans Referred for Colonoscopy,” DDW

2019, San Diego, CA, May 2019• “Colonoscopy Volume of Colonic Irrigation (VOCI) and Rate of Adequate Bowel Prep and

Adenomas per Colonoscopy,” DDW 2019, San Diego, CA, May 2019• “Rate of Inappropriate FIT Testing at a VA Healthcare System,” DDW 2019, San Diego, CA, May

2019Awards

• First Place Research Award, Performance of the Veterans Choice Program for ColonoscopyReferrals at a Tertiary VA Center, VA Pittsburgh Healthcare System’s 2019 Research Week,Pittsburgh, PA, May 2019

• Named Team Member, Selected to name the best IBD research abstracts at DDW 2019, DDW2019, San Diego, CA, May 2019

Mohannad Dugum, MDPublications

• Kakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-Related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-1363.

• Glass D, Huang DT, Dugum M, Chintamaneni P, Cua S, Saul M, Marsh W, Al-Khafaji A. RectalTrumpet-Associated Hemorrhage in the Intensive Care Unit: A Quality Improvement Initiative. JWound Ostomy Continence Nurs. 2018 Nov/Dec;45(6):516-520.

• Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I,O'Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severityof Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Adam Gluskin, MDPublications

• Keswani RN, Benson M, Beveridge C, Gawron AJ, Gluskin AB, Kahi CJ, Kaltenbach TR, McClure J,Schenck R, Yadlapati RH, Duloy A. Colonoscopy-Naïve Raters Can Be Trained to AssessColonoscopy Quality. Clin Gastroenterol Hepatol. 2019 Jun 20. Epub ahead of print]

• Yadlapati R, Johnston ER, Gluskin AB, Gregory DL, Cyrus R, Werth L, Ciolino JD, Grande DP,Keswani RN. An automated inpatient split dose bowel preparation improves colonoscopy qualityand reduces repeat procedures. J Clin Gasteroenterol 2018;52(8):709-14.

Presentations and Abstracts• “Rate of inappropriate FIT testing at a VA health care system,” DDW 2019, San Diego, CA, May

2019• “The quality of early acute pancreatitis management has improved minimally over time,” DDW

2019, San Diego, CA, May 2019• “Admitting actue pancreatitis patietns who require intensive care to the floor is common and

Residency: Duke University HospitalCurrent Position: Advanced Endoscopy Fellow, NYU Langone Health

R. Warren Sands, MD, PhDMedical School: Northwestern UniversityResidency: University of Pittsburgh Medical CenterCurrent Position: Hepatology Fellow, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh

Fellow ActivitiesCatherine Bartnik, MD

Publications• Bartnik CM, Maheshwari RN, Subramanian RM. Beating the Odds: A Full-Term Delivery After Liver

Transplantation of a Pregnant Hyperthyroid Patient at 19 Weeks' Gestation for Propylthiouracil-Induced Acute Liver Failure. Transplant Proc. 2018 Dec;50(10):3995-3999.

Weston Bettner, MDPresentations and Abstracts

• Can We Develop Precision Medicine for Biologic Selection in IBD Based on Routinely Available Clinical Information? Using Big Data Analytics to Identify Predictors of Anti-TNF Response, ACG 2018 Annual Scientific Meeting, Philadelphia, PA, 10/1/2018

• Peripheral blood eosinophilia functions as a candidate biomarker of decreased response to anti-TNF therapy in Crohn’s disease, DDW 2019, San Diego, CA, 5/1/2019

Hui-Wei (Doris) Chen, MDPublications

• Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Sood P, Rachakonda V, Dunn MA, Tevar AD. Gait Speed and Grip Strength are associated with Dropping Out of the Liver Transplant Waiting List. Transplant Proc. 2019 Apr;51(3):794-97.

• Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC. Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Man Undergoing Urgent Evaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

Presentations and Abstracts• “A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve

Physical Function in Patients with Advanced Liver Disease,” American Transplant Congress, Boston, MA, June 2019

• “A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve Physical Function in Patients with Advanced Liver Disease,” Department of Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019

Jeffrey Dueker, MDPublications

• Dueker JM, Luty J, Perry DJ, Izumi S, Fromme EK, and DiVeronica M. A Resident-Led Initiative to Increase Documentation of Surrogate Decision Makers for Hospitalized Patients. J Grad Med Educ. 2019 Jun;11(3):295-300.

44



AASLD Academic Debates, AASLD The Liver Meeting 2018, San Francisco, CA, November 2018• “Sarcopenia as a Tool to Predict Post-Liver Transplant (LT) Mortality in the Acutely Ill LT

Candidate,” AASLD The Liver Meeting, San Francisco, November 2018• “CON: No, we would not transplant a hepatitis C positive liver into this hepatitis C negative

recipient,” American Liver Foundation Academic Debates, Cleveland, OH, December 2018• “The Poop Scoop: Stool-Based Diagnoses Made Ridiculously Simple,” 4th Annual Fellows’

Teaching Competition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, April 2019

• “Provider Perceptions of HCV Treatment Adherence,” DDW 2019, San Diego, CA, May 2019• “Harderoporphyria: clinical, biochemical and molecular features in an adult male,” Annual Alpha-1

National Conference, Orlando, FL, June 2019Awards

• Travel Grant, Fellows' Symposium in Transplantation 2018, American Society of Transplantation, September 2018

• Sub Investigator, INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP, ClinicalTrials.gov Identifier: NCT03547297, September 2018

• Winner, No, we would not transplant a hepatitis C positive liver into this hepatitis C negative recipient, AASLD Academic Debates, AASLD The Liver Meeting, San Francisco, CA, November 2018

• Selected Team, AASLD Academic Debates, AASLD The Liver Meeting, San Francisco, CA, November 2018

• Resident/Fellow Ambassador Award & Travel Grant, AASLD The Liver Meeting, San Francisco, CA, November 2018

• 2nd Runner-up, 4th Annual Fellows’ Teaching Competition, The Poop Scoop: Stool-Based Diagnosis Made Rediculously Simple, 4th Annual Fellows' Teaching Competition, Department of Medicine, Pittsburgh, PA, April 2019

Kohtaro (Cody) Ooka, MDPublications

• Ooka K, Fasanella KE, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer. Gastroenterology. 2019;156(4):e10-e1.

• Madhani K, Yousaf M, Aamar A, Ooka K, Muniraj T, Aslanian H, et al. Impact of endoscopic ultrasound on diagnosis and management of presumed mucinous neoplasms when done for pancreatic cyst morphology change on non-invasive surveillance imaging. Endosc Int Open. 2019;7(4):e389-e95.

• Connolly JJ, Ooka K, Lim JK. Future Pharmacotherapy for Non-alcoholic Steatohepatitis (NASH): Review of Phase 2 and 3 Trials. J Clin Transl Hepatol. 2018 Sep 28;6(3):264-275.

Presentations and Abstracts• “The clinical specturm of groove pancreatitis is much wider thanit is believed,” DDW 2019, San

Diego, CA, May 2019

Ajay Singhvi, MDPublications

associated with poor outcomes,” DDW 2019, San Diego, CA, May 2019

Diana Jaiyeola, MDPresentations and Abstracts

• “Performance of noninvasive laboratory-based liver fibrosis scoring tests in nonalcoholic fatty liverdisease patients with extreme obesity,” DDW 2019, San Diego, CA, May 2019

• “Type 2 Diabetes Mellitus is Associated with Significantly Higher Risk of Mortality and Extra-hepatic Cancers in Biopsy-proven Non-advanced Nonalcoholic Fatty Liver Disease,” DDW 2019,San Diego, CA, May 2019

Matthew Klinge, MDPresentations and Abstracts

• Academic Debate, AASLD - The Liver Meeting, San Francisco, CA, November 2018• Academic Debates, American Liver Foundation, Cleveland, OH, December 2018

Bassem Matta, MDPublications

• Dugum, M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I,O’Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of dietary habits with severityof acute pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Presentations and Abstracts• “Safety and efficacy of colonic band ligation and autoamputation for large and laterally spreading

lesions and polyps in difficult locations, DDW 2019, San Diego, CA, 5/1/2019• Regional Variations of Clinical Characteristics in Acute Pancreatitis from a Large, International,

Multi-center Prospective Study (APPRENTICE Study Group),” PancreasFest 2018, Pittsburgh, PA,July 2018

• “Coexistence of alcoholic liver disease (ald) and alcoholic pancreatitis (alp),” DDW 2019, SanDiego, CA, May 2019

Akshata Moghe, MD, PhDPublications

• Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell J, Pradhan-Sundd T, Liu S,Singh S, Poddar M, Monga J, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen H, Monga, SP.Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. Cell Metab. 2019 May 7;29(5):1135-1150.e6.

• Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M,Lai JC. Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Man Undergoing UrgentEvaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

• Moghe A, Ramanujam VMS, Phillips JD, Desnick RJ, Anderson KE. Harderoporphyria: Case oflifelong photosensitivity associated with compound heterozygous coproporphyrinogen oxidase(CPOX) mutations. Mol Genet Metab Rep. 2019 Feb 19;19:100457.

• Moghe A, Shaikh OS. Hepatitis C related hepatocellular carcinoma in the era of direct-actingantivirals. Hepatoma Research. 2018 July 18;4:36.

Presentations and Abstracts• “Biopsy vs. Noninvasive Assessment of NASH PRO: This Patient Should Have a Liver Biopsy,”

45



AASLD Academic Debates, AASLD The Liver Meeting 2018, San Francisco, CA, November 2018• “Sarcopenia as a Tool to Predict Post-Liver Transplant (LT) Mortality in the Acutely Ill LT

Candidate,” AASLD The Liver Meeting, San Francisco, November 2018• “CON: No, we would not transplant a hepatitis C positive liver into this hepatitis C negative

recipient,” American Liver Foundation Academic Debates, Cleveland, OH, December 2018• “The Poop Scoop: Stool-Based Diagnoses Made Ridiculously Simple,” 4th Annual Fellows’

Teaching Competition, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, April2019

• “Provider Perceptions of HCV Treatment Adherence,” DDW 2019, San Diego, CA, May 2019• “Harderoporphyria: clinical, biochemical and molecular features in an adult male,” Annual Alpha-1

National Conference, Orlando, FL, June 2019Awards

• Travel Grant, Fellows' Symposium in Transplantation 2018, American Society of Transplantation,September 2018

• Sub Investigator, INSIGHT-AHP: A Study to Characterize the Prevalence of Acute HepaticPorphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP,ClinicalTrials.gov Identifier: NCT03547297, September 2018

• Winner, No, we would not transplant a hepatitis C positive liver into this hepatitis C negativerecipient, AASLD Academic Debates, AASLD The Liver Meeting, San Francisco, CA, November2018

• Selected Team, AASLD Academic Debates, AASLD The Liver Meeting, San Francisco, CA,November 2018

• Resident/Fellow Ambassador Award & Travel Grant, AASLD The Liver Meeting, San Francisco, CA,November 2018

• 2nd Runner-up, 4th Annual Fellows’ Teaching Competition, The Poop Scoop: Stool-BasedDiagnosis Made Rediculously Simple, 4th Annual Fellows' Teaching Competition, Department ofMedicine, Pittsburgh, PA, April 2019

Kohtaro (Cody) Ooka, MDPublications

• Ooka K, Fasanella KE, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer.Gastroenterology. 2019;156(4):e10-e1.

• Madhani K, Yousaf M, Aamar A, Ooka K, Muniraj T, Aslanian H, et al. Impact of endoscopicultrasound on diagnosis and management of presumed mucinous neoplasms when done forpancreatic cyst morphology change on non-invasive surveillance imaging. Endosc Int Open.2019;7(4):e389-e95.

• Connolly JJ, Ooka K, Lim JK. Future Pharmacotherapy for Non-alcoholic Steatohepatitis (NASH):Review of Phase 2 and 3 Trials. J Clin Transl Hepatol. 2018 Sep 28;6(3):264-275.

Presentations and Abstracts• “The clinical specturm of groove pancreatitis is much wider thanit is believed,” DDW 2019, San

Diego, CA, May 2019

Ajay Singhvi, MDPublications

associated with poor outcomes,” DDW 2019, San Diego, CA, May 2019

Diana Jaiyeola, MDPresentations and Abstracts

• “Performance of noninvasive laboratory-based liver fibrosis scoring tests in nonalcoholic fatty liver disease patients with extreme obesity,” DDW 2019, San Diego, CA, May 2019

• “Type 2 Diabetes Mellitus is Associated with Significantly Higher Risk of Mortality and Extra-hepatic Cancers in Biopsy-proven Non-advanced Nonalcoholic Fatty Liver Disease,” DDW 2019, San Diego, CA, May 2019

Matthew Klinge, MDPresentations and Abstracts

• Academic Debate, AASLD - The Liver Meeting, San Francisco, CA, November 2018• Academic Debates, American Liver Foundation, Cleveland, OH, December 2018

Bassem Matta, MDPublications

• Dugum, M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O’Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of dietary habits with severity of acute pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Presentations and Abstracts• “Safety and efficacy of colonic band ligation and autoamputation for large and laterally spreading

lesions and polyps in difficult locations, DDW 2019, San Diego, CA, 5/1/2019• Regional Variations of Clinical Characteristics in Acute Pancreatitis from a Large, International,

Multi-center Prospective Study (APPRENTICE Study Group),” PancreasFest 2018, Pittsburgh, PA, July 2018

• “Coexistence of alcoholic liver disease (ald) and alcoholic pancreatitis (alp),” DDW 2019, San Diego, CA, May 2019

Akshata Moghe, MD, PhDPublications

• Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell J, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga J, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen H, Monga, SP. Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. Cell Metab. 2019 May 7;29(5):1135-1150.e6.

• Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC. Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Man Undergoing Urgent Evaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

• Moghe A, Ramanujam VMS, Phillips JD, Desnick RJ, Anderson KE. Harderoporphyria: Case of lifelong photosensitivity associated with compound heterozygous coproporphyrinogen oxidase (CPOX) mutations. Mol Genet Metab Rep. 2019 Feb 19;19:100457.

• Moghe A, Shaikh OS. Hepatitis C related hepatocellular carcinoma in the era of direct-acting antivirals. Hepatoma Research. 2018 July 18;4:36.

Presentations and Abstracts• “Biopsy vs. Noninvasive Assessment of NASH PRO: This Patient Should Have a Liver Biopsy,”

46



• Singhvi A, Yadav D. Myths and realities about alcohol and smoking in chronic pancreatitis. CurrOpin Gastroenterol. 2018 Sep;34(5):355-61.

Presentations and Abstracts• “Expedited Inpatient Work-Up for Suspected Non-Metastatic Pancreatic Cancer Is Associated

With Greater Resource Utilization but Questionable Clinical Benefit,” American College of Gastroenterology Annual Meeting, Philadelphia, PA, October 2018

• “Coexistence of Alcoholic Liver Disease (ALD) and Alcoholic Pancreatitis (ALP),” Department ofMedicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019

• “Coexistence of Alcoholic Liver Disease (ALD) and Alcoholic Pancreatitis (ALP),” DDW 2019, SanDiego, CA, May 2019

Awards• Pancreas Scholar Award (one of 6 fellows selected in the U.S.), CAPER, Collaborative Alliance for

Pancreatic Education & Research (CAPER) Pancreas Scholars Program, December 2018• Attendee, National Pancreas Fondation Fellows' Symposium, Chicago, IL, May 2019

Kishore Vipperla, MDPresentations and Abstracts

• “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Duration of ChronicPancreatitis,” Department of Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019

• “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Duration of ChronicPancreatitis,” DDW 2019 Research Forum, San Diego, CA, May 2019

Awards• Early Stage Investigator Award (in recognition of scientific accomplishment for DDW 2019 oral

presentation), “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Durationof Chronic Pancreatitis,” DDW 2019 Research Forum, San Diego, CA, May 2019

Postdoctoral Fellows, FY2019

Brandon Blobner, PhDMentor: David C. Whitcomb, MD, PhDDr. Blobner researches pancreas genetics, particularly NAPS2.

Vikram K. Raghu, PhDMentor: Jeffrey A. Rudolph, MDDr. Raghu is conducting a clinical decision analysis to improve care for intestinal failure patients.

R. Warren Sands, MD, PhDMentor: David G. Binion, MDDr. Sands is working to identify aberrant signaling pathways in IBD.

THREE-YEAR BIBLIOGRAPHY High impact publications are italicized

Robert E. Schoen, MD, MPH Division Chief

Ma P, Beatty PL, McKolanis J, Brand R, Schoen RE, Finn OJ. Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer. Front Immunol. 2019 Jun 19;10:1401.

Pardini B, Corrado A, Paolicchi E, Cugliari G, Berndt SI, Bezieau S, Bien SA, Brenner H, Caan BJ, Campbell PT, Casey G, Chan AT, Chang-Claude J, Cotterchio M, Gala M, Gallinger SJ, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hsu L, Huyghe J, Jenkins MA, Le Marchand L, Lin Y, Lindor NM, Nan H, Newcomb PA, Ogino S, Potter JD, Schoen RE, Slattery ML, White E, Vodickova L, Vymetalkova V, Vodicka P, Gemignani F, Peters U, Naccarati A, Landi S. DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility. Int J Cancer. 2019 Jun 17.

Wang X, Dai JY, Albanes D, Arndt V, Berndt SI, Bézieau S, Brenner H, Buchanan DD, Butterbach K, Caan B, Casey G, Campbell PT, Chan AT, Chen Z, Chang-Claude J, Cotterchio M, Easton DF, Giles GG, Giovannucci E, Grady WM, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi AD, Lampe JW, Larsson SC, Lejbkowicz F, Li L, Lindblom A, Le Marchand L, Martin V, Milne RL, Moreno V, Newcomb PA, Offitt K, Ogino S, Pharoah PDP, Pinchev M, Potter JD, Rennert HS, Rennert G, Saliba W, Schafmayer C, Schoen RE, Schrotz-King P, Slattery ML, Song M, Stegmaier C, Weinstein SJ, Wolk A, Woods MO, Wu AH, Gruber SB, Peters U, White E. Mendelian randomization analysis of C-reactive protein on colorectal cancer risk. Int J Epidemiol. 2019 Jun 1;48(3):767-780.

McNabb S, Harrison TA, Albanes D, Berndt SI, Brenner H, Caan BJ, Campbell PT, Cao Y, Chang-Claude J, Chan A, Chen Z, English DR, Giles GG, Giovannucci EL, Goodman PJ, Hayes RB, Hoffmeister M, Jacobs EJ, Joshi AD, Larsson SC, Le Marchand L, Li L, Lin Y, Männistö S, Milne RL, Nan H, Newton CC, Ogino S, Parfrey PS, Petersen PS, Potter JD, Schoen RE, Slattery ML, Su YR, Tangen CM, Tucker TC, Weinstein SJ, White E, Wolk A, Woods MO, Phipps AI, Peters U. Meta-analysis of 16 studies of the association of alcohol with colorectal cancer. Int J Cancer. 2019 Apr 29.

Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L. BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5. Cancer Res. 2019 Mar 15;79(6):1191-1203.

Miller EA, Pinsky PF, Schoen RE, Prorok PC, Church TR. Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: long-term follow-up of the randomised US PLCO cancer screening trial. Lancet Gastroenterol Hepatol. 2019 Feb;4(2):101-110.

Huyghe JR, Bien SA, Harrison TA, Kang HM, Chen S, Schmit SL, Conti DV, Qu C, Jeon J, Edlund CK, Greenside P, Wainberg M, Schumacher FR, Smith JD, Levine DM, Nelson SC, Sinnott-Armstrong NA, Albanes D, Alonso MH, Anderson K, Arnau-Collell C, Arndt V, Bamia C, Banbury BL, Baron JA, Berndt SI, Bézieau S, Bishop DT, Boehm J, Boeing H, Brenner H, Brezina S, Buch S, Buchanan DD, Burnett-Hartman A, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castellví-Bel S, Chan AT, Chang-Claude J, Chanock SJ, Chirlaque MD, Cho SH, Connolly CM, Cross AJ, Cuk K, Curtis KR, de la Chapelle A, Doheny KF, Duggan D, Easton DF, Elias SG, Elliott F, English DR, Feskens EJM, Figueiredo JC, Fischer R, FitzGerald LM, Forman D, Gala M, Gallinger

47



• Singhvi A, Yadav D. Myths and realities about alcohol and smoking in chronic pancreatitis. Curr Opin Gastroenterol. 2018 Sep;34(5):355-61.

Presentations and Abstracts• “Expedited Inpatient Work-Up for Suspected Non-Metastatic Pancreatic Cancer Is Associated

With Greater Resource Utilization but Questionable Clinical Benefit,” American College of Gastroenterology Annual Meeting, Philadelphia, PA, October 2018

• “Coexistence of Alcoholic Liver Disease (ALD) and Alcoholic Pancreatitis (ALP),” Department of Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019

• “Coexistence of Alcoholic Liver Disease (ALD) and Alcoholic Pancreatitis (ALP),” DDW 2019, San Diego, CA, May 2019

Awards• Pancreas Scholar Award (one of 6 fellows selected in the U.S.), CAPER, Collaborative Alliance for

Pancreatic Education & Research (CAPER) Pancreas Scholars Program, December 2018• Attendee, National Pancreas Fondation Fellows' Symposium, Chicago, IL, May 2019

Kishore Vipperla, MDPresentations and Abstracts

• “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Duration of Chronic Pancreatitis,” Department of Medicine Research Day, University of Pittsburgh, Pittsburgh, PA, April 2019

• “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Duration of Chronic Pancreatitis,” DDW 2019 Research Forum, San Diego, CA, May 2019

Awards• Early Stage Investigator Award (in recognition of scientific accomplishment for DDW 2019 oral

presentation), “Pain ‘Burn-out’ during the Natural Disease Course is Independent of the Duration of Chronic Pancreatitis,” DDW 2019 Research Forum, San Diego, CA, May 2019

Postdoctoral Fellows, FY2019

Brandon Blobner, PhDMentor: David C. Whitcomb, MD, PhDDr. Blobner researches pancreas genetics, particularly NAPS2.

Vikram K. Raghu, PhDMentor: Jeffrey A. Rudolph, MDDr. Raghu is conducting a clinical decision analysis to improve care for intestinal failure patients.

R. Warren Sands, MD, PhDMentor: David G. Binion, MDDr. Sands is working to identify aberrant signaling pathways in IBD.

THREE-YEAR BIBLIOGRAPHY High impact publications are italicized

Robert E. Schoen, MD, MPH Division Chief

Ma P, Beatty PL, McKolanis J, Brand R, Schoen RE, Finn OJ. Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer. Front Immunol. 2019 Jun 19;10:1401.

Pardini B, Corrado A, Paolicchi E, Cugliari G, Berndt SI, Bezieau S, Bien SA, Brenner H, Caan BJ, Campbell PT, Casey G, Chan AT, Chang-Claude J, Cotterchio M, Gala M, Gallinger SJ, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hsu L, Huyghe J, Jenkins MA, Le Marchand L, Lin Y, Lindor NM, Nan H, Newcomb PA, Ogino S, Potter JD, Schoen RE, Slattery ML, White E, Vodickova L, Vymetalkova V, Vodicka P, Gemignani F, Peters U, Naccarati A, Landi S. DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility. Int J Cancer. 2019 Jun 17.

Wang X, Dai JY, Albanes D, Arndt V, Berndt SI, Bézieau S, Brenner H, Buchanan DD, Butterbach K, Caan B, Casey G, Campbell PT, Chan AT, Chen Z, Chang-Claude J, Cotterchio M, Easton DF, Giles GG, Giovannucci E, Grady WM, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi AD, Lampe JW, Larsson SC, Lejbkowicz F, Li L, Lindblom A, Le Marchand L, Martin V, Milne RL, Moreno V, Newcomb PA, Offitt K, Ogino S, Pharoah PDP, Pinchev M, Potter JD, Rennert HS, Rennert G, Saliba W, Schafmayer C, Schoen RE, Schrotz-King P, Slattery ML, Song M, Stegmaier C, Weinstein SJ, Wolk A, Woods MO, Wu AH, Gruber SB, Peters U, White E. Mendelian randomization analysis of C-reactive protein on colorectal cancer risk. Int J Epidemiol. 2019 Jun 1;48(3):767-780.

McNabb S, Harrison TA, Albanes D, Berndt SI, Brenner H, Caan BJ, Campbell PT, Cao Y, Chang-Claude J, Chan A, Chen Z, English DR, Giles GG, Giovannucci EL, Goodman PJ, Hayes RB, Hoffmeister M, Jacobs EJ, Joshi AD, Larsson SC, Le Marchand L, Li L, Lin Y, Männistö S, Milne RL, Nan H, Newton CC, Ogino S, Parfrey PS, Petersen PS, Potter JD, Schoen RE, Slattery ML, Su YR, Tangen CM, Tucker TC, Weinstein SJ, White E, Wolk A, Woods MO, Phipps AI, Peters U. Meta-analysis of 16 studies of the association of alcohol with colorectal cancer. Int J Cancer. 2019 Apr 29.

Tan X, Tong J, Wang YJ, Fletcher R, Schoen RE, Yu J, Shen L, Zhang L. BET Inhibitors Potentiate Chemotherapy and Killing of SPOP-Mutant Colon Cancer Cells via Induction of DR5. Cancer Res. 2019 Mar 15;79(6):1191-1203.

Miller EA, Pinsky PF, Schoen RE, Prorok PC, Church TR. Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: long-term follow-up of the randomised US PLCO cancer screening trial. Lancet Gastroenterol Hepatol. 2019 Feb;4(2):101-110.

Huyghe JR, Bien SA, Harrison TA, Kang HM, Chen S, Schmit SL, Conti DV, Qu C, Jeon J, Edlund CK, Greenside P, Wainberg M, Schumacher FR, Smith JD, Levine DM, Nelson SC, Sinnott-Armstrong NA, Albanes D, Alonso MH, Anderson K, Arnau-Collell C, Arndt V, Bamia C, Banbury BL, Baron JA, Berndt SI, Bézieau S, Bishop DT, Boehm J, Boeing H, Brenner H, Brezina S, Buch S, Buchanan DD, Burnett-Hartman A, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castellví-Bel S, Chan AT, Chang-Claude J, Chanock SJ, Chirlaque MD, Cho SH, Connolly CM, Cross AJ, Cuk K, Curtis KR, de la Chapelle A, Doheny KF, Duggan D, Easton DF, Elias SG, Elliott F, English DR, Feskens EJM, Figueiredo JC, Fischer R, FitzGerald LM, Forman D, Gala M, Gallinger

48



S, Gauderman WJ, Giles GG, Gillanders E, Gong J, Goodman PJ, Grady WM, Grove JS, Gsur A, Gunter MJ, Haile RW, Hampe J, Hampel H, Harlid S, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Hsu WL, Huang WY, Hudson TJ, Hunter DJ, Ibañez-Sanz G, Idos GE, Ingersoll R, Jackson RD, Jacobs EJ, Jenkins MA, Joshi AD, Joshu CE, Keku TO, Key TJ, Kim HR, Kobayashi E, Kolonel LN, Kooperberg C, Kühn T, Küry S, Kweon SS, Larsson SC, Laurie CA, Le Marchand L, Leal SM, Lee SC, Lejbkowicz F, Lemire M, Li CI, Li L, Lieb W, Lin Y, Lindblom A, Lindor NM, Ling H, Louie TL, Männistö S, Markowitz SD, Martín V, Masala G, McNeil CE, Melas M, Milne RL, Moreno L, Murphy N, Myte R, Naccarati A, Newcomb PA, Offit K, Ogino S, Onland-Moret NC, Pardini B, Parfrey PS, Pearlman R, Perduca V, Pharoah PDP, Pinchev M, Platz EA, Prentice RL, Pugh E, Raskin L, Rennert G, Rennert HS, Riboli E, Rodríguez-Barranco M, Romm J, Sakoda LC, Schafmayer C, Schoen RE, Seminara D, Shah M, Shelford T, Shin MH, Shulman K, Sieri S, Slattery ML, Southey MC, Stadler ZK, Stegmaier C, Su YR, Tangen CM, Thibodeau SN, Thomas DC, Thomas SS, Toland AE, Trichopoulou A, Ulrich CM, Van Den Berg DJ, van Duijnhoven FJB, Van Guelpen B, van Kranen H, Vijai J, Visvanathan K, Vodicka P, Vodickova L, Vymetalkova V, Weigl K, Weinstein SJ, White E, Win AK, Wolf CR, Wolk A, Woods MO, Wu AH, Zaidi SH, Zanke BW, Zhang Q, Zheng W, Scacheri PC, Potter JD, Bassik MC, Kundaje A, Casey G, Moreno V, Abecasis GR, Nickerson DA, Gruber SB, Hsu L, Peters U. Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet. 2019 Jan;51(1):76-87.

Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA, Huyghe JR, Qu C, Melas M, Van Den Berg DJ, Wang H, Tring S, Plummer SJ, Albanes D, Alonso MH, Amos CI, Anton K, Aragaki AK, Arndt V, Barry EL, Berndt SI, Bezieau S, Bien S, Bloomer A, Boehm J, Boutron-Ruault MC, Brenner H, Brezina S, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castelao JE, Chan AT, Chang-Claude J, Chanock SJ, Cheng I, Cheng YW, Chin LS, Church JM, Church T, Coetzee GA, Cotterchio M, Cruz Correa M, Curtis KR, Duggan D, Easton DF, English D, Feskens EJM, Fischer R, FitzGerald LM, Fortini BK, Fritsche LG, Fuchs CS, Gago-Dominguez M, Gala M, Gallinger SJ, Gauderman WJ, Giles GG, Giovannucci EL, Gogarten SM, Gonzalez-Villalpando C, Gonzalez-Villalpando EM, Grady WM, Greenson JK, Gsur A, Gunter M, Haiman CA, Hampe J, Harlid S, Harju JF, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Huang SC, Huerta JM, Hudson TJ, Hunter DJ, Idos GE, Iwasaki M, Jackson RD, Jacobs EJ, Jee SH, Jenkins MA, Jia WH, Jiao S, Joshi AD, Kolonel LN, Kono S, Kooperberg C, Krogh V, Kuehn T, Küry S, LaCroix A, Laurie CA, Lejbkowicz F, Lemire M, Lenz HJ, Levine D, Li CI, Li L, Lieb W, Lin Y, Lindor NM, Liu YR, Loupakis F, Lu Y, Luh F, Ma J, Mancao C, Manion FJ, Markowitz SD, Martin V, Matsuda K, Matsuo K, McDonnell KJ, McNeil CE, Milne R, Molina AJ, Mukherjee B, Murphy N, Newcomb PA, Offit K, Omichessan H, Palli D, Cotoré JPP, Pérez-Mayoral J, Pharoah PD, Potter JD, Qu C, Raskin L, Rennert G, Rennert HS, Riggs BM, Schafmayer C, Schoen RE, Sellers TA, Seminara D, Severi G, Shi W, Shibata D, Shu XO, Siegel EM, Slattery ML, Southey M, Stadler ZK, Stern MC, Stintzing S, Taverna D, Thibodeau SN, Thomas DC, Trichopoulou A, Tsugane S, Ulrich CM, van Duijnhoven FJB, van Guelpan B, Vijai J, Virtamo J, Weinstein SJ, White E, Win AK, Wolk A, Woods M, Wu AH, Wu K, Xiang YB, Yen Y, Zanke BW, Zeng YX, Zhang B, Zubair N, Kweon SS, Figueiredo JC, Zheng W, Marchand LL, Lindblom A, Moreno V, Peters U, Casey G, Hsu L, Conti DV, Gruber SB. Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst. 2019 Feb 1;111(2):146-157.

Chun KA, Kocarnik JM, Hardikar SS, Robinson JR, Berndt SI, Chan AT, Figueiredo JC, Lindor NM, Song M, Schoen RE, Hayes RB, Potter JD, Nassir R, Bézieau S, Le Marchand L, Slattery ML, White E, Peters U, Newcomb PA. Leptin gene variants and colorectal cancer risk: Sex-specific associations. PLoS One. 2018 Oct 31;13(10):e0206519.

Liang PS, Allison J, Ladabaum U, Martinez ME, Murphy CC, Schoen RE, Shaukat A, Tinmouth J, Gupta S. Potential Intended and Unintended Consequences of Recommending Initiation of Colorectal Cancer

Screening at Age 45 Years. Gastroenterology. 2018 Oct;155(4):950-954.

Pinsky PF, Loberg M, Senore C, Wooldrage K, Atkin W, Bretthauer M, Cross AJ, Hoff G, Holme O, Kalager M,Segnan N, Schoen RE. Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening. Gastroenterology. 2018 Oct;155(4):1059-1068.e2.

Ertem FU, Ladabaum U, Mehrotra A, Tehranian S, Shi Z, Saul M, Morris M, Crockett SD, Schoen RE. Incidence of interval colorectal cancer attributable to an endoscopist in clinical practice. Gastrointest Endosc. 2018 Oct;88(4):705-711.e1.

Crockett SD, Gourevitch RA, Morris M, Carrell DS, Rose S, Shi Z, Greer JB, Schoen RE, Mehrotra A. Endoscopist factors that influence serrated polyp detection: a multicenter study. Endoscopy. 2018 Oct;50(10):984-992.

Wang X, Chan AT, Slattery ML, Chang-Claude J, Potter JD, Gallinger S, Caan B, Lampe JW, Newcomb PA, Zubair N, Hsu L, Schoen RE, Hoffmeister M, Brenner H, Le Marchand L, Peters U, White E. Influence of Smoking, Body Mass Index, and Other Factors on the Preventive Effect of Nonsteroidal Anti-Inflammatory Drugs on Colorectal Cancer Risk. Cancer Res. 2018 Aug 15;78(16):4790-4799.

Neumeyer S, Banbury BL, Arndt V, Berndt SI, Bezieau S, Bien SA, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Casey G, Chan AT, Chanock SJ, Dai JY, Gallinger S, Giovannucci EL, Giles GG, Grady WM, Hampe J, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi A, Larsson SC, Le Marchand L, Lindblom A, Moreno V, Lemire M, Li L, Lin Y, Offit K, Newcomb PA, Pharaoh PD, Potter JD, Qi L, Rennert G, Schafmayer C, Schoen RE, Slattery ML, Song M, Ulrich CM, Win AK, White E, Wolk A, Woods MO, Wu AH, Gruber SB, Brenner H, Peters U, Chang-Claude J. Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer. Br J Cancer. 2018 Jun;118(12):1639-1647.

Jeon J, Du M, Schoen RE, Hoffmeister M, Newcomb PA, Berndt SI, Caan B, Campbell PT, Chan AT, Chang-Claude J, Giles GG, Gong J, Harrison TA, Huyghe JR, Jacobs EJ, Li L, Lin Y, Le Marchand L, Potter JD, Qu C, Bien SA, Zubair N, Macinnis RJ, Buchanan DD, Hopper JL, Cao Y, Nishihara R, Rennert G, Slattery ML, Thomas DC, Woods MO, Prentice RL, Gruber SB, Zheng Y, Brenner H, Hayes RB, White E, Peters U, Hsu L; Colorectal Transdisciplinary Study and Genetics and Epidemiology of Colorectal Cancer Consortium. Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors. Gastroenterology. 2018 Jun;154(8):2152-2164.e19.

Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE. Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence. JAMA. 2018 May 15;319(19):2021-2031.

Su YR, Di C, Bien S, Huang L, Dong X, Abecasis G, Berndt S, Bezieau S, Brenner H, Caan B, Casey G, Chang-Claude J, Chanock S, Chen S, Connolly C, Curtis K, Figueiredo J, Gala M, Gallinger S, Harrison T, Hoffmeister M, Hopper J, Huyghe JR, Jenkins M, Joshi A, Le Marchand L, Newcomb P, Nickerson D, Potter J, Schoen R, Slattery M, White E, Zanke B, Peters U, Hsu L. A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics. Am J Hum Genet. 2018 May 3;102(5):904-919.

Marcondes FO, Gourevitch RA, Schoen RE, Crockett SD, Morris M, Mehrotra A. Adenoma Detection Rate Falls at the End of the Day in a Large Multi-site Sample. Dig Dis Sci. 2018 Apr;63(4):856-859.

Click B, Anderson AM, Ramos Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Szigethy E, Regueiro M, Schoen RE, Binion DG. Telephone Encounters Predict Future High Financial Expenditures in Inflammatory Bowel Disease Patients: A 3-Year Prospective Observational Study. J

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S, Gauderman WJ, Giles GG, Gillanders E, Gong J, Goodman PJ, Grady WM, Grove JS, Gsur A, Gunter MJ, Haile RW, Hampe J, Hampel H, Harlid S, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Hsu WL, Huang WY, Hudson TJ, Hunter DJ, Ibañez-Sanz G, Idos GE, Ingersoll R, Jackson RD, Jacobs EJ, Jenkins MA, Joshi AD, Joshu CE, Keku TO, Key TJ, Kim HR, Kobayashi E, Kolonel LN, Kooperberg C, Kühn T, Küry S, Kweon SS, Larsson SC, Laurie CA, Le Marchand L, Leal SM, Lee SC, Lejbkowicz F, Lemire M, Li CI, Li L, Lieb W, Lin Y, Lindblom A, Lindor NM, Ling H, Louie TL, Männistö S, Markowitz SD, Martín V, Masala G, McNeil CE, Melas M, Milne RL, Moreno L, Murphy N, Myte R, Naccarati A, Newcomb PA, Offit K, Ogino S, Onland-Moret NC, Pardini B, Parfrey PS, Pearlman R, Perduca V, Pharoah PDP, Pinchev M, Platz EA, Prentice RL, Pugh E, Raskin L, Rennert G, Rennert HS, Riboli E, Rodríguez-Barranco M, Romm J, Sakoda LC, Schafmayer C, Schoen RE, Seminara D, Shah M, Shelford T, Shin MH, Shulman K, Sieri S, Slattery ML, Southey MC, Stadler ZK, Stegmaier C, Su YR, Tangen CM, Thibodeau SN, Thomas DC, Thomas SS, Toland AE, Trichopoulou A, Ulrich CM, Van Den Berg DJ, van Duijnhoven FJB, Van Guelpen B, van Kranen H, Vijai J, Visvanathan K, Vodicka P, Vodickova L, Vymetalkova V, Weigl K, Weinstein SJ, White E, Win AK, Wolf CR, Wolk A, Woods MO, Wu AH, Zaidi SH, Zanke BW, Zhang Q, Zheng W, Scacheri PC, Potter JD, Bassik MC, Kundaje A, Casey G, Moreno V, Abecasis GR, Nickerson DA, Gruber SB, Hsu L, Peters U. Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet. 2019 Jan;51(1):76-87.

Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA, Huyghe JR, Qu C, Melas M, Van Den Berg DJ, Wang H, Tring S, Plummer SJ, Albanes D, Alonso MH, Amos CI, Anton K, Aragaki AK, Arndt V, Barry EL, Berndt SI, Bezieau S, Bien S, Bloomer A, Boehm J, Boutron-Ruault MC, Brenner H, Brezina S, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Castelao JE, Chan AT, Chang-Claude J, Chanock SJ, Cheng I, Cheng YW, Chin LS, Church JM, Church T, Coetzee GA, Cotterchio M, Cruz Correa M, Curtis KR, Duggan D, Easton DF, English D, Feskens EJM, Fischer R, FitzGerald LM, Fortini BK, Fritsche LG, Fuchs CS, Gago-Dominguez M, Gala M, Gallinger SJ, Gauderman WJ, Giles GG, Giovannucci EL, Gogarten SM, Gonzalez-Villalpando C, Gonzalez-Villalpando EM, Grady WM, Greenson JK, Gsur A, Gunter M, Haiman CA, Hampe J, Harlid S, Harju JF, Hayes RB, Hofer P, Hoffmeister M, Hopper JL, Huang SC, Huerta JM, Hudson TJ, Hunter DJ, Idos GE, Iwasaki M, Jackson RD, Jacobs EJ, Jee SH, Jenkins MA, Jia WH, Jiao S, Joshi AD, Kolonel LN, Kono S, Kooperberg C, Krogh V, Kuehn T, Küry S, LaCroix A, Laurie CA, Lejbkowicz F, Lemire M, Lenz HJ, Levine D, Li CI, Li L, Lieb W, Lin Y, Lindor NM, Liu YR, Loupakis F, Lu Y, Luh F, Ma J, Mancao C, Manion FJ, Markowitz SD, Martin V, Matsuda K, Matsuo K, McDonnell KJ, McNeil CE, Milne R, Molina AJ, Mukherjee B, Murphy N, Newcomb PA, Offit K, Omichessan H, Palli D, Cotoré JPP, Pérez-Mayoral J, Pharoah PD, Potter JD, Qu C, Raskin L, Rennert G, Rennert HS, Riggs BM, Schafmayer C, Schoen RE, Sellers TA, Seminara D, Severi G, Shi W, Shibata D, Shu XO, Siegel EM, Slattery ML, Southey M, Stadler ZK, Stern MC, Stintzing S, Taverna D, Thibodeau SN, Thomas DC, Trichopoulou A, Tsugane S, Ulrich CM, van Duijnhoven FJB, van Guelpan B, Vijai J, Virtamo J, Weinstein SJ, White E, Win AK, Wolk A, Woods M, Wu AH, Wu K, Xiang YB, Yen Y, Zanke BW, Zeng YX, Zhang B, Zubair N, Kweon SS, Figueiredo JC, Zheng W, Marchand LL, Lindblom A, Moreno V, Peters U, Casey G, Hsu L, Conti DV, Gruber SB. Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst. 2019 Feb 1;111(2):146-157.

Chun KA, Kocarnik JM, Hardikar SS, Robinson JR, Berndt SI, Chan AT, Figueiredo JC, Lindor NM, Song M, Schoen RE, Hayes RB, Potter JD, Nassir R, Bézieau S, Le Marchand L, Slattery ML, White E, Peters U, Newcomb PA. Leptin gene variants and colorectal cancer risk: Sex-specific associations. PLoS One. 2018 Oct 31;13(10):e0206519.

Liang PS, Allison J, Ladabaum U, Martinez ME, Murphy CC, Schoen RE, Shaukat A, Tinmouth J, Gupta S. Potential Intended and Unintended Consequences of Recommending Initiation of Colorectal Cancer

Screening at Age 45 Years. Gastroenterology. 2018 Oct;155(4):950-954.

Pinsky PF, Loberg M, Senore C, Wooldrage K, Atkin W, Bretthauer M, Cross AJ, Hoff G, Holme O, Kalager M,Segnan N, Schoen RE. Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening. Gastroenterology. 2018 Oct;155(4):1059-1068.e2.

Ertem FU, Ladabaum U, Mehrotra A, Tehranian S, Shi Z, Saul M, Morris M, Crockett SD, Schoen RE. Incidence of interval colorectal cancer attributable to an endoscopist in clinical practice. Gastrointest Endosc. 2018 Oct;88(4):705-711.e1.


Wang X, Chan AT, Slattery ML, Chang-Claude J, Potter JD, Gallinger S, Caan B, Lampe JW, Newcomb PA, Zubair N, Hsu L, Schoen RE, Hoffmeister M, Brenner H, Le Marchand L, Peters U, White E. Influence of Smoking, Body Mass Index, and Other Factors on the Preventive Effect of Nonsteroidal Anti-Inflammatory Drugs on Colorectal Cancer Risk. Cancer Res. 2018 Aug 15;78(16):4790-4799.

Neumeyer S, Banbury BL, Arndt V, Berndt SI, Bezieau S, Bien SA, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Casey G, Chan AT, Chanock SJ, Dai JY, Gallinger S, Giovannucci EL, Giles GG, Grady WM, Hampe J, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi A, Larsson SC, Le Marchand L, Lindblom A, Moreno V, Lemire M, Li L, Lin Y, Offit K, Newcomb PA, Pharaoh PD, Potter JD, Qi L, Rennert G, Schafmayer C, Schoen RE, Slattery ML, Song M, Ulrich CM, Win AK, White E, Wolk A, Woods MO, Wu AH, Gruber SB, Brenner H, Peters U, Chang-Claude J. Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer. Br J Cancer. 2018 Jun;118(12):1639-1647.

Jeon J, Du M, Schoen RE, Hoffmeister M, Newcomb PA, Berndt SI, Caan B, Campbell PT, Chan AT, Chang-Claude J, Giles GG, Gong J, Harrison TA, Huyghe JR, Jacobs EJ, Li L, Lin Y, Le Marchand L, Potter JD, Qu C, Bien SA, Zubair N, Macinnis RJ, Buchanan DD, Hopper JL, Cao Y, Nishihara R, Rennert G, Slattery ML, Thomas DC, Woods MO, Prentice RL, Gruber SB, Zheng Y, Brenner H, Hayes RB, White E, Peters U, Hsu L; Colorectal Transdisciplinary Study and Genetics and Epidemiology of Colorectal Cancer Consortium. Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors. Gastroenterology. 2018 Jun;154(8):2152-2164.e19.

Click B, Pinsky PF, Hickey T, Doroudi M, Schoen RE. Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence. JAMA. 2018 May 15;319(19):2021-2031.

Su YR, Di C, Bien S, Huang L, Dong X, Abecasis G, Berndt S, Bezieau S, Brenner H, Caan B, Casey G, Chang-Claude J, Chanock S, Chen S, Connolly C, Curtis K, Figueiredo J, Gala M, Gallinger S, Harrison T, Hoffmeister M, Hopper J, Huyghe JR, Jenkins M, Joshi A, Le Marchand L, Newcomb P, Nickerson D, Potter J, Schoen R, Slattery M, White E, Zanke B, Peters U, Hsu L. A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics. Am J Hum Genet. 2018 May 3;102(5):904-919.

Marcondes FO, Gourevitch RA, Schoen RE, Crockett SD, Morris M, Mehrotra A. Adenoma Detection Rate Falls at the End of the Day in a Large Multi-site Sample. Dig Dis Sci. 2018 Apr;63(4):856-859.


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Mehrotra A, Morris M, Gourevitch RA, Carrell DS, Leffler DA, Rose S, Greer JB, Crockett SD, Baer A, SchoenRE. Physician characteristics associated with higher adenoma detection rate. Gastrointest Endosc. 2018 Mar;87(3):778-786.e5.

Gourevitch RA, Rose S, Crockett SD, Morris M, Carrell DS, Greer JB, Pai RK, Schoen RE, Mehrotra A. Variation in Pathologist Classification of Colorectal Adenomas and Serrated Polyps. Am J Gastroenterol. 2018 Mar;113(3):431-439.

Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018 Feb 7;10(427).

Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz LA Jr, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science. 2018 Feb 23;359(6378):926-930.

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Di Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Farooqi IS, Faul JD, Fauser S, Feng S, Ferrannini E, Ferrieres J, Florez JC, Ford I, Fornage M, Franco OH, Franke A, Franks PW, Friedrich N, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Gibson J, Giedraitis V, Gjesing AP, Gordon-Larsen P, Gorski M, Grabe HJ, Grant SFA, Grarup N, Griffiths HL, Grove ML, Gudnason V, Gustafsson S, Haessler J, Hakonarson H, Hammerschlag AR, Hansen T, Harris KM, Harris TB, Hattersley AT, Have CT, Hayward C, He L, Heard-Costa NL, Heath AC, Heid IM, Helgeland Ø, Hernesniemi J, Hewitt AW, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Huang PL, Huffman JE, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jia Y, Johansson S, Jørgensen ME, Jørgensen T, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SLR, Karpe F, Kathiresan S, Kee F, Kiemeney LA, Kim E, Kitajima H, Komulainen P, Kooner JS, Kooperberg C, Korhonen T, Kovacs P, Kuivaniemi H, Kutalik Z, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange EM, Lange LA, Langenberg C, Larson EB, Lee NR, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin KH, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Liu Y, Lo KS, Lophatananon A, Lotery AJ, Loukola A, Luan J, Lubitz SA, Lyytikäinen LP, Männistö S, Marenne G, Mazul AL, McCarthy MI, McKean-Cowdin R, Medland SE, Meidtner K, Milani L, Mistry V, Mitchell P, Mohlke KL, Moilanen L, Moitry M, Montgomery GW, Mook-Kanamori DO, Moore C, Mori

TA, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Narisu N, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Nyholt DR, O'Connel JR, O'Donoghue ML, Olde Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CNA, Palmer ND, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Person TN, Peters A, Petersen ERB, Peyser PA, Pirie A, Polasek O, Polderman TJ, Puolijoki H, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Renström F, Rheinberger M, Ridker PM, Rioux JD, Rivas MA, Roberts DJ, Robertson NR, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sapkota Y, Sattar N, Schoen RE, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah SH, Sheu WH, Sim X, Slater AJ, Small KS, Smith AV, Southam L, Spector TD, Speliotes EK, Starr JM, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swift AJ, Tada H, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Uusitupa M, Laan SW, Duijn CM, Leeuwen N, van Setten J, Vanhala M, Varbo A, Varga TV, Varma R, Velez Edwards DR, Vermeulen SH, Veronesi G, Vestergaard H, Vitart V, Vogt TF, Völker U, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wang Y, Ware EB, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Witte DR, Wood AR, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zhou W, Zondervan KT; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetic Consortium; GoT2D Genes Consortium; EPIC InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; MAGIC Investigators; Understanding Society Scientific Group, Rotter JI, Pospisilik JA, Rivadeneira F, Borecki IB, Deloukas P, Frayling TM, Lettre G, North KE, Lindgren CM, Hirschhorn JN, Loos RJF. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet. 2018 Jan;50(1):26-41.

Doroudi M, Schoen RE, Pinsky PF. Early detection versus primary prevention in the PLCO flexible sigmoidoscopy screening trial: Which has the greatest impact on mortality? Cancer. 2017 Dec 15;123(24):4815-4822.

Bien SA, Auer PL, Harrison TA, Qu C, Connolly CM, Greenside PG, Chen S, Berndt SI, Bézieau S, Kang HM, Huyghe J, Brenner H, Casey G, Chan AT, Hopper JL, Banbury BL, Chang-Claude J, Chanock SJ, Haile RW, Hoffmeister M, Fuchsberger C, Jenkins MA, Leal SM, Lemire M, Newcomb PA, Gallinger S, Potter JD, Schoen RE, Slattery ML, Smith JD, Le Marchand L, White E, Zanke BW, Abeçasis GR, Carlson CS, Peters U, Nickerson DA, Kundaje A, Hsu L; GECCO and CCFR. Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data. PLoS One. 2017 Nov 21;12(11):e0186518.

Carrell DS, Schoen RE, Leffler DA, Morris M, Rose S, Baer A, Crockett SD, Gourevitch RA, Dean KM, Mehrotra A. Challenges in adapting existing clinical natural language processing systems to multiple, diverse health care settings. J Am Med Inform Assoc. 2017 Sep 1;24(5):986-991.

Holme Ø, Schoen RE, Senore C, Segnan N, Hoff G, Løberg M, Bretthauer M, Adami HO, Kalager M. Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials. BMJ. 2017 Jan 13;356:i6673.

Shi J, Park JH, Duan J, Berndt ST, Moy W, Yu K, Song L, Wheeler W, Hua X, Silverman D, Garcia-Closas M, Hsiung CA, Figueroa JD, Cortessis VK, Malats N, Karagas MR, Vineis P, Chang IS, Lin D, Zhou B, Seow A, Matsuo K, Hong YC, Caporaso NE, Wolpin B, Jacobs E, Petersen GM, Klein AP, Li D, Risch H, Sanders AR,

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Mehrotra A, Morris M, Gourevitch RA, Carrell DS, Leffler DA, Rose S, Greer JB, Crockett SD, Baer A, SchoenRE. Physician characteristics associated with higher adenoma detection rate. Gastrointest Endosc. 2018 Mar;87(3):778-786.e5.


Leibowitz BJ, Yang L, Wei L, Buchanan ME, Rachid M, Parise RA, Beumer JH, Eiseman JL, Schoen RE, Zhang L, Yu J. Targeting p53-dependent stem cell loss for intestinal chemoprotection. Sci Transl Med. 2018 Feb 7;10(427).


Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Di Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Farooqi IS, Faul JD, Fauser S, Feng S, Ferrannini E, Ferrieres J, Florez JC, Ford I, Fornage M, Franco OH, Franke A, Franks PW, Friedrich N, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Gibson J, Giedraitis V, Gjesing AP, Gordon-Larsen P, Gorski M, Grabe HJ, Grant SFA, Grarup N, Griffiths HL, Grove ML, Gudnason V, Gustafsson S, Haessler J, Hakonarson H, Hammerschlag AR, Hansen T, Harris KM, Harris TB, Hattersley AT, Have CT, Hayward C, He L, Heard-Costa NL, Heath AC, Heid IM, Helgeland Ø, Hernesniemi J, Hewitt AW, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Huang PL, Huffman JE, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jia Y, Johansson S, Jørgensen ME, Jørgensen T, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SLR, Karpe F, Kathiresan S, Kee F, Kiemeney LA, Kim E, Kitajima H, Komulainen P, Kooner JS, Kooperberg C, Korhonen T, Kovacs P, Kuivaniemi H, Kutalik Z, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange EM, Lange LA, Langenberg C, Larson EB, Lee NR, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin KH, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Liu Y, Lo KS, Lophatananon A, Lotery AJ, Loukola A, Luan J, Lubitz SA, Lyytikäinen LP, Männistö S, Marenne G, Mazul AL, McCarthy MI, McKean-Cowdin R, Medland SE, Meidtner K, Milani L, Mistry V, Mitchell P, Mohlke KL, Moilanen L, Moitry M, Montgomery GW, Mook-Kanamori DO, Moore C, Mori

TA, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Narisu N, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Nyholt DR, O'Connel JR, O'Donoghue ML, Olde Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CNA, Palmer ND, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Person TN, Peters A, Petersen ERB, Peyser PA, Pirie A, Polasek O, Polderman TJ, Puolijoki H, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Renström F, Rheinberger M, Ridker PM, Rioux JD, Rivas MA, Roberts DJ, Robertson NR, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sapkota Y, Sattar N, Schoen RE, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah SH, Sheu WH, Sim X, Slater AJ, Small KS, Smith AV, Southam L, Spector TD, Speliotes EK, Starr JM, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swift AJ, Tada H, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Uusitupa M, Laan SW, Duijn CM, Leeuwen N, van Setten J, Vanhala M, Varbo A, Varga TV, Varma R, Velez Edwards DR, Vermeulen SH, Veronesi G, Vestergaard H, Vitart V, Vogt TF, Völker U, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wang Y, Ware EB, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Witte DR, Wood AR, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhao W, Zhou W, Zondervan KT; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetic Consortium; GoT2D Genes Consortium; EPIC InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; MAGIC Investigators; Understanding Society Scientific Group, Rotter JI, Pospisilik JA, Rivadeneira F, Borecki IB, Deloukas P, Frayling TM, Lettre G, North KE, Lindgren CM, Hirschhorn JN, Loos RJF. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet. 2018 Jan;50(1):26-41.

Doroudi M, Schoen RE, Pinsky PF. Early detection versus primary prevention in the PLCO flexible sigmoidoscopy screening trial: Which has the greatest impact on mortality? Cancer. 2017 Dec 15;123(24):4815-4822.

Bien SA, Auer PL, Harrison TA, Qu C, Connolly CM, Greenside PG, Chen S, Berndt SI, Bézieau S, Kang HM, Huyghe J, Brenner H, Casey G, Chan AT, Hopper JL, Banbury BL, Chang-Claude J, Chanock SJ, Haile RW, Hoffmeister M, Fuchsberger C, Jenkins MA, Leal SM, Lemire M, Newcomb PA, Gallinger S, Potter JD, Schoen RE, Slattery ML, Smith JD, Le Marchand L, White E, Zanke BW, Abeçasis GR, Carlson CS, Peters U, Nickerson DA, Kundaje A, Hsu L; GECCO and CCFR. Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data. PLoS One. 2017 Nov 21;12(11):e0186518.

Carrell DS, Schoen RE, Leffler DA, Morris M, Rose S, Baer A, Crockett SD, Gourevitch RA, Dean KM, Mehrotra A. Challenges in adapting existing clinical natural language processing systems to multiple, diverse health care settings. J Am Med Inform Assoc. 2017 Sep 1;24(5):986-991.

Holme Ø, Schoen RE, Senore C, Segnan N, Hoff G, Løberg M, Bretthauer M, Adami HO, Kalager M. Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: pooled analysis of randomised trials. BMJ. 2017 Jan 13;356:i6673.

Shi J, Park JH, Duan J, Berndt ST, Moy W, Yu K, Song L, Wheeler W, Hua X, Silverman D, Garcia-Closas M, Hsiung CA, Figueroa JD, Cortessis VK, Malats N, Karagas MR, Vineis P, Chang IS, Lin D, Zhou B, Seow A, Matsuo K, Hong YC, Caporaso NE, Wolpin B, Jacobs E, Petersen GM, Klein AP, Li D, Risch H, Sanders AR,

52



Hsu L, Schoen RE, Brenner H; MGS (Molecular Genetics of Schizophrenia) GWAS Consortium; GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium); GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium; PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium; PanScan Consortium; GAME-ON/ELLIPSE Consortium, Stolzenberg-Solomon R, Gejman P, Lan Q, Rothman N, Amundadottir LT, Landi MT, Levinson DF, Chanock SJ, Chatterjee N. Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016 Dec 30;12(12):e1006493.

Gong J, Hutter CM, Newcomb PA, Ulrich CM, Bien SA, Campbell PT, Baron JA, Berndt SI, Bezieau S, Brenner H, Casey G, Chan AT, Chang-Claude J, Du M, Duggan D, Figueiredo JC, Gallinger S, Giovannucci EL, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jeon J, Jenkins MA, Kocarnik J, Küry S, Le Marchand L, Lin Y, Lindor NM, Nishihara R, Ogino S, Potter JD, Rudolph A, Schoen RE, Schrotz-King P, Seminara D, Slattery ML, Thibodeau SN, Thornquist M, Toth R, Wallace R, White E, Jiao S, Lemire M, Hsu L, Peters U; CCFR and GECCO. Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. PLoS Genet. 2016 Oct 10;12(10):e1006296.

Fehringer G, Kraft P, Pharoah PD, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindström S, Brennan P, Bickeböller H, Houlston RS, Landi MT, Caporaso N, Risch A, Amin Al Olama A, Berndt SI, Giovannucci EL, Grönberg H, Kote-Jarai Z, Ma J, Muir K, Stampfer MJ, Stevens VL, Wiklund F, Willett WC, Goode EL, Permuth JB, Risch HA, Reid BM, Bezieau S, Brenner H, Chan AT, Chang-Claude J, Hudson TJ, Kocarnik JK, Newcomb PA, Schoen RE, Slattery ML, White E, Adank MA, Ahsan H, Aittomäki K, Baglietto L, Blomquist C, Canzian F, Czene K, Dos-Santos-Silva I, Eliassen AH, Figueroa JD, Flesch-Janys D, Fletcher O, Garcia-Closas M, Gaudet MM, Johnson N, Hall P, Hazra A, Hein R, Hofman A, Hopper JL, Irwanto A, Johansson M, Kaaks R, Kibriya MG, Lichtner P, Liu J, Lund E, Makalic E, Meindl A, Müller-Myhsok B, Muranen TA, Nevanlinna H, Peeters PH, Peto J, Prentice RL, Rahman N, Sanchez MJ, Schmidt DF, Schmutzler RK, Southey MC, Tamimi R, Travis RC, Turnbull C, Uitterlinden AG, Wang Z, Whittemore AS, Yang XR, Zheng W, Buchanan DD, Casey G, Conti DV, Edlund CK, Gallinger S, Haile RW, Jenkins M, Le Marchand L, Li L, Lindor NM, Schmit SL, Thibodeau SN, Woods MO, Rafnar T, Gudmundsson J, Stacey SN, Stefansson K, Sulem P, Chen YA, Tyrer JP, Christiani DC, Wei Y, Shen H, Hu Z, Shu XO, Shiraishi K, Takahashi A, Bossé Y, Obeidat M, Nickle D, Timens W, Freedman ML, Li Q, Seminara D, Chanock SJ, Gong J, Peters U, Gruber SB, Amos CI, Sellers TA, Easton DF, Hunter DJ, Haiman CA, Henderson BE, Hung RJ; Ovarian Cancer Association Consortium (OCAC); PRACTICAL Consortium; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); Colorectal Transdisciplinary (CORECT) Study; African American Breast Cancer Consortium (AABC) and African Ancestry Prostate Cancer Consortium (AAPC). Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. Cancer Res. 2016 Sep 1;76(17):5103-14.

Kocarnik JM, Chan AT, Slattery ML, Potter JD, Meyerhardt J, Phipps A, Nan H, Harrison T, Rohan TE, Qi L, Hou L, Caan B, Kroenke CH, Strickler H, Hayes RB, Schoen RE, Chong DQ, White E, Berndt SI, Peters U, Newcomb PA. Relationship of prediagnostic body mass index with survival after colorectal cancer: Stage-specific associations. Int J Cancer. 2016 Sep 1;139(5):1065-72.

Negm OH, Hamed MR, Schoen RE, Whelan RL, Steele RJ, Scholefield J, Dilnot EM, Shantha Kumara HM, Robertson JF, Sewell HF. Human Blood Autoantibodies in the Detection of Colorectal Cancer. PLoS One. 2016 Jul 6;11(7):e0156971.

Du M, Jiao S, Bien SA, Gala M, Abecasis G, Bezieau S, Brenner H, Butterbach K, Caan BJ, Carlson CS, Casey G, Chang-Claude J, Conti DV, Curtis KR, Duggan D, Gallinger S, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Küry S, Le Marchand L, Leal SM, Newcomb PA, Nickerson DA, Potter JD, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Hsu L, Chan AT, White E, Berndt SI, Peters U. Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants. PLoS One. 2016 Jul 5;11(7):e0157521.

Steven R. Abo, MDChiu WK, Brand RM, Camp D, Edick S, Mitchell C, Karas S, Zehmisch A, Ho K, Brand RE, Harrison J, Abo S, Cranston RD, McGowan I. The Safety of Multiple Flexible Sigmoidoscopies with Mucosal Biopsies in Healthy Clinical Trial Participants. AIDS Res Hum Retroviruses. 2017 Aug;33(8):820-826.

Jana G. Al Hashash, MD, MSc*

Uttam S, Hashash JG, LaFace J, Binion D, Regueiro M, Hartman DJ, Brand RE, Liu Y. Three-dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease. Cancer Prev Res (Phila). Epub 2019 Jun 4.

Hashash JG, Ibrahim D, Rizk NA. An Uncommon Cause of Fever and Altered Levels of Liver Enzymes. Gastroenterology. 2019 Mar;156(6):1574-75.

Ooka K, Fasanella K, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer. Gastroenterology. 2019 Mar;156(4):e10-e11.

Daniel F, Hassoun L, Husni M, Sharara A, Soweid A, Barada K, Haffar B, Massoud R, Shaib Y, Al-Hashash J, Bazarbachi A, El Cheikh J. Site Specific Diagnostic Yield of Endoscopic Biopsies in Gastrointestinal Graft-versus-Host Disease: A Tertiary Care Center Experience. Curr Res Transl Med. 2019 Feb;67(1):16-19.

Hashash JG, Vachon A, Ramos Rivers C, Regueiro MD, Binion DG, Altman L, Williams C, Szigethy E. Predictors of Suicidal Ideation Among IBD Outpatients. J Clin Gastroenterol. 2019 Jan;53(1):e41-e45.

Lakkis B, El Chediak A, Hashash JG, Koubar SH. Severe Ketoacidosis in a Patient with Spinal Muscular Atrophy. CEN Case Rep. 2018 Nov;7(2):292-295.

Nammour T, Dagher M, Hashash JG. Rubbery Purple and Red Lesions in the Gastrointestinal Tract: A Case of Gastrointestinal Tract Kaposi Sarcoma. Clin Gastroenterol Hepatol. 2019 Jan;17(1):e3-e4.

Anderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz Md, Regueiro M, Binion D. Low Rates of Dermatologic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-39.

Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun;24(7):1380-88.

Hashash JG, Ramos-Rivers C, Youk A, Chiu WK, Duff K, Regueiro M, Binion DG, Koutroubakis I, Vachon A, Benhayon D, Dunn MA, Szigethy EM. Quality of Sleep and Coexistent Psychopathology Have Significant Impact on Fatigue Burden in Patients With Inflammatory Bowel Disease. J Clin Gastroenterol. 2018 May/Jun;52(5):423-430.

53



Hsu L, Schoen RE, Brenner H; MGS (Molecular Genetics of Schizophrenia) GWAS Consortium; GECCO (The Genetics and Epidemiology of Colorectal Cancer Consortium); GAME-ON/TRICL (Transdisciplinary Research in Cancer of the Lung) GWAS Consortium; PRACTICAL (PRostate cancer AssoCiation group To Investigate Cancer Associated aLterations) Consortium; PanScan Consortium; GAME-ON/ELLIPSE Consortium, Stolzenberg-Solomon R, Gejman P, Lan Q, Rothman N, Amundadottir LT, Landi MT, Levinson DF, Chanock SJ, Chatterjee N. Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data. PLoS Genet. 2016 Dec 30;12(12):e1006493.

Gong J, Hutter CM, Newcomb PA, Ulrich CM, Bien SA, Campbell PT, Baron JA, Berndt SI, Bezieau S, Brenner H, Casey G, Chan AT, Chang-Claude J, Du M, Duggan D, Figueiredo JC, Gallinger S, Giovannucci EL, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jeon J, Jenkins MA, Kocarnik J, Küry S, Le Marchand L, Lin Y, Lindor NM, Nishihara R, Ogino S, Potter JD, Rudolph A, Schoen RE, Schrotz-King P, Seminara D, Slattery ML, Thibodeau SN, Thornquist M, Toth R, Wallace R, White E, Jiao S, Lemire M, Hsu L, Peters U; CCFR and GECCO. Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer. PLoS Genet. 2016 Oct 10;12(10):e1006296.

Fehringer G, Kraft P, Pharoah PD, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindström S, Brennan P, Bickeböller H, Houlston RS, Landi MT, Caporaso N, Risch A, Amin Al Olama A, Berndt SI, Giovannucci EL, Grönberg H, Kote-Jarai Z, Ma J, Muir K, Stampfer MJ, Stevens VL, Wiklund F, Willett WC, Goode EL, Permuth JB, Risch HA, Reid BM, Bezieau S, Brenner H, Chan AT, Chang-Claude J, Hudson TJ, Kocarnik JK, Newcomb PA, Schoen RE, Slattery ML, White E, Adank MA, Ahsan H, Aittomäki K, Baglietto L, Blomquist C, Canzian F, Czene K, Dos-Santos-Silva I, Eliassen AH, Figueroa JD, Flesch-Janys D, Fletcher O, Garcia-Closas M, Gaudet MM, Johnson N, Hall P, Hazra A, Hein R, Hofman A, Hopper JL, Irwanto A, Johansson M, Kaaks R, Kibriya MG, Lichtner P, Liu J, Lund E, Makalic E, Meindl A, Müller-Myhsok B, Muranen TA, Nevanlinna H, Peeters PH, Peto J, Prentice RL, Rahman N, Sanchez MJ, Schmidt DF, Schmutzler RK, Southey MC, Tamimi R, Travis RC, Turnbull C, Uitterlinden AG, Wang Z, Whittemore AS, Yang XR, Zheng W, Buchanan DD, Casey G, Conti DV, Edlund CK, Gallinger S, Haile RW, Jenkins M, Le Marchand L, Li L, Lindor NM, Schmit SL, Thibodeau SN, Woods MO, Rafnar T, Gudmundsson J, Stacey SN, Stefansson K, Sulem P, Chen YA, Tyrer JP, Christiani DC, Wei Y, Shen H, Hu Z, Shu XO, Shiraishi K, Takahashi A, Bossé Y, Obeidat M, Nickle D, Timens W, Freedman ML, Li Q, Seminara D, Chanock SJ, Gong J, Peters U, Gruber SB, Amos CI, Sellers TA, Easton DF, Hunter DJ, Haiman CA, Henderson BE, Hung RJ; Ovarian Cancer Association Consortium (OCAC); PRACTICAL Consortium; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); Colorectal Transdisciplinary (CORECT) Study; African American Breast Cancer Consortium (AABC) and African Ancestry Prostate Cancer Consortium (AAPC). Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. Cancer Res. 2016 Sep 1;76(17):5103-14.

Kocarnik JM, Chan AT, Slattery ML, Potter JD, Meyerhardt J, Phipps A, Nan H, Harrison T, Rohan TE, Qi L, Hou L, Caan B, Kroenke CH, Strickler H, Hayes RB, Schoen RE, Chong DQ, White E, Berndt SI, Peters U, Newcomb PA. Relationship of prediagnostic body mass index with survival after colorectal cancer: Stage-specific associations. Int J Cancer. 2016 Sep 1;139(5):1065-72.

Negm OH, Hamed MR, Schoen RE, Whelan RL, Steele RJ, Scholefield J, Dilnot EM, Shantha Kumara HM, Robertson JF, Sewell HF. Human Blood Autoantibodies in the Detection of Colorectal Cancer. PLoS One. 2016 Jul 6;11(7):e0156971.

Du M, Jiao S, Bien SA, Gala M, Abecasis G, Bezieau S, Brenner H, Butterbach K, Caan BJ, Carlson CS, Casey G, Chang-Claude J, Conti DV, Curtis KR, Duggan D, Gallinger S, Haile RW, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Küry S, Le Marchand L, Leal SM, Newcomb PA, Nickerson DA, Potter JD, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Hsu L, Chan AT, White E, Berndt SI, Peters U. Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants. PLoS One. 2016 Jul 5;11(7):e0157521.

Steven R. Abo, MDChiu WK, Brand RM, Camp D, Edick S, Mitchell C, Karas S, Zehmisch A, Ho K, Brand RE, Harrison J, Abo S, Cranston RD, McGowan I. The Safety of Multiple Flexible Sigmoidoscopies with Mucosal Biopsies in Healthy Clinical Trial Participants. AIDS Res Hum Retroviruses. 2017 Aug;33(8):820-826.

Jana G. Al Hashash, MD, MSc*

Uttam S, Hashash JG, LaFace J, Binion D, Regueiro M, Hartman DJ, Brand RE, Liu Y. Three-dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease. Cancer Prev Res (Phila). Epub 2019 Jun 4.

Hashash JG, Ibrahim D, Rizk NA. An Uncommon Cause of Fever and Altered Levels of Liver Enzymes. Gastroenterology. 2019 Mar;156(6):1574-75.

Ooka K, Fasanella K, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer. Gastroenterology. 2019 Mar;156(4):e10-e11.

Daniel F, Hassoun L, Husni M, Sharara A, Soweid A, Barada K, Haffar B, Massoud R, Shaib Y, Al-Hashash J, Bazarbachi A, El Cheikh J. Site Specific Diagnostic Yield of Endoscopic Biopsies in Gastrointestinal Graft-versus-Host Disease: A Tertiary Care Center Experience. Curr Res Transl Med. 2019 Feb;67(1):16-19.


Lakkis B, El Chediak A, Hashash JG, Koubar SH. Severe Ketoacidosis in a Patient with Spinal Muscular Atrophy. CEN Case Rep. 2018 Nov;7(2):292-295.

Nammour T, Dagher M, Hashash JG. Rubbery Purple and Red Lesions in the Gastrointestinal Tract: A Case of Gastrointestinal Tract Kaposi Sarcoma. Clin Gastroenterol Hepatol. 2019 Jan;17(1):e3-e4.




54



Click B, Anderson AM, Ramos Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Szigethy E, Regueiro M, Schoen RE, Binion DG. Telephone Encounters Predict Future High Financial Expenditures in Inflammatory Bowel Disease Patients: A 3-Year Prospective Observational Study. J Clin Gastroenterol. 2018 Apr;52(4):319-325.

Johnson CM, Hartman DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Al Hashash J, Barrie A, Pfanner TP, Dunn M, Koutroubakis IE, Binion DG. Epithelioid Granulomas Associate with Increased Severity and Progression of Crohn's Disease, Based on 6-Year Follow-Up. Clin Gastroenterol Hepatol. 2018 Jun;16(6):900-907.e1.

Francis FF, Kulich S, Hashash JG. Duodenal Scalloping Diagnoses Waldenström Macroglobulinemia. Clin Gastroenterol Hepatol. 2018 Apr 13 [Epub ahead of print].

Gajendran M, Bauer AJ, Buchholz BM, Watson AR, Koutroubakis IE, Hashash JG, Ramos-Rivers C, Shah N, Lee KK, Cruz RJ, Regueiro M, Zuckerbraun B, Schwartz M, Swoger J, Barrie A, Harrison J, Hartman DJ, Salgado J, Rivers WM, Click B, Anderson AM, Umapathy C, Babichenko D, Dunn MA, Binion DG. Ileocecal Anastomosis Type Significantly Influences Long-Term Functional Status, Quality of Life, and Healthcare Utilization in Postoperative Crohn's Disease Patients Independent of Inflammation Recurrence. Am J Gastroenterol. 2018 Apr;113(4):576-583.

Hashash JG, El-Haddad A, Barada K. Acute Epigastric Abdominal Pain Post-Gastric Polypectomy. Gastroenterology. 2018 Mar;154(4):e12-e14.

Kakar S, Manzo CE, Hashash JG. An Unusual Cause of a Retroperitoneal Fluid Collection. Gastroenterology. 2018 Jan;154(1):33-34.

Hashash JG, Minervini M, Cruz RJ Jr. Black Stoma: What Could It Be? Gastroenterology. 2017 Dec;153(6):e12-e13.

Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG. Peripheral Eosinophilia in Patients with Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype. Am J Gastroenterol. 2017 Dec;112(12):1849-1858.

Anderson A, Click B, Ramos-Rivers C, Cheng D, Babichenko D, Koutroubakis IE, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Lasting Impact of Clostridium Difficile Infection in Inflammatory Bowel Disease: A Propensity Score Matched Analysis. Inflamm Bowel Dis. 2017 Dec;23(12):2180-2188.

Cranston RD, Regueiro M, Hashash J, Baker JR, Richardson-Harman N, Janocko L, McGowan I. A Pilot Study of the Prevalence of Anal Human Papillomavirus and Dysplasia in a Cohort of Patients With IBD. Dis Colon Rectum. 2017 Dec;60(12):1307-1313.

Francis FF, Frye R, Hashash JG. Cholelithiasis and Biliary Cirrhosis in a 28-Year-Old Man. Clin Gastroenterol Hepatol. 2017 May;15(5):A31-A32.

Rao BB, Click BH, Koutroubakis IE, Ramos Rivers C, Regueiro M, Swoger J, Schwartz M, Hashash J, Barrie A, Dunn MA, Binion DG. The Cost of Crohn's Disease: Varied Health Care Expenditure Patterns Across Distinct Disease Trajectories. Inflamm Bowel Dis. 2017 Jan;23(1):107-115.

Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz

M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Development of an Inflammatory Bowel Disease Research Registry Derived from Observational Electronic Health Record Data for Comprehensive Clinical Phenotyping. Dig Dis Sci. 2016 Nov;61(11):3236-3245.

Hashash JG, Sigal R, Wein-Levy P, Szigethy EM, Merusi JJ, Regueiro MD. Inflammatory Bowel Disease (IBD) Connect: A Novel Volunteer Program for Hospitalized Patients with IBD and Their Families. Inflamm Bowel Dis. 2016 Nov;22(11):2748-2753.

Bhattacharya A, Rao BB, Koutroubakis IE, Click B, Vargas EJ, Regueiro M, Schwartz M, Swoger JM, Babichenko D, Hartmann D, Rivers CR, Barrie A 3rd, Hashash JG, Dunn MA, Binion DG. Silent Crohn's Disease Predicts Increased Bowel Damage During Multiyear Follow-up: The Consequences of Under-reporting Active Inflammation. Inflamm Bowel Dis. 2016 Nov;22(11):2665-2671.

Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schwartz M, Swoger J, Baidoo L, Hashash JG, Barrie A, Dunn MA, Binion DG. Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. J Clin Gastroenterol. 2016 Sep;50(8)638-643.

Bhagya Rao B, Koutroubakis IE, Ramos Rivers C, Colombel JF, Regueiro M, Swoger J, Schwartz M, Baidoo L, Hashash J, Barrie A, Dunn MA, Binion DG. Delineation of Crohn's Disease Trajectories Using Change in Lémann Index: A Natural History Study. J Clin Gastroenterol. 2016 Jul;50(6):476-82.

Jiang J, Click B, Anderson AM, Koutroubakis IE, Rivers CR, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A, Regueiro M, Chang CC, Binion DG. Group-Based Trajectory Modeling of Healthcare Financial Charges in Inflammatory Bowel Disease: A Comprehensive Phenotype. Clin Transl Gastroenterol. 2016 Jul 14;7(7):e181.

Beatty PL, van der Geest R, Hashash JG, Kimura T, Gutkin D, Brand RE, Finn OJ. Immunobiology and immunosurveillance in patients with intraductal papillary mucinous neoplasms (IPMNs), premalignant precursors of pancreatic adenocarcinomas. Cancer Immunol Immunother. 2016 Jul;65(7):771-8.

Kathryn M. Albers, PhDSaloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Grown Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018 Aug;47(7):856-63.

Makadia PA, Najjar SA, Saloman JL, Adelman P, Feng B, Margiotta JF, Albers KM, Davis BM. Optogenetic Activation of Colon Epithelium of the Mouse Produces High-Frequency Bursting in Extrinsic Colon Afferents and Engages Visceromotor Responses. J Neurosci. 2018 Jun 20;38(25):5788-5798.

DeBerry JJ, Samineni VK, Copits BA, Sullivan CJ, Vogt SK, Albers KM, Davis BM, Gereau RW IV. Differential Regulation of Bladder Pain and Voiding Function by Sensory Afferent Populations Revealed by Selective Optogenetic Activation. Front Integr Neurosci. 2018 Feb 12;12:5.

Jankowski MP, Baumbauer KM, Wang T, Albers KM, Davis BM, Koerber HR. Cutaneous neurturin overexpression alters mechanical, thermal, and cold responsiveness in physiologically identified primary afferents. J Neurophysiol. 2017 Mar 1;117(3):1258-1265.

55





Francis FF, Kulich S, Hashash JG. Duodenal Scalloping Diagnoses Waldenström Macroglobulinemia. Clin Gastroenterol Hepatol. 2018 Apr 13 [Epub ahead of print].


Hashash JG, El-Haddad A, Barada K. Acute Epigastric Abdominal Pain Post-Gastric Polypectomy. Gastroenterology. 2018 Mar;154(4):e12-e14.

Kakar S, Manzo CE, Hashash JG. An Unusual Cause of a Retroperitoneal Fluid Collection. Gastroenterology. 2018 Jan;154(1):33-34.

Hashash JG, Minervini M, Cruz RJ Jr. Black Stoma: What Could It Be? Gastroenterology. 2017 Dec;153(6):e12-e13.


Anderson A, Click B, Ramos-Rivers C, Cheng D, Babichenko D, Koutroubakis IE, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Lasting Impact of Clostridium Difficile Infection in Inflammatory Bowel Disease: A Propensity Score Matched Analysis. Inflamm Bowel Dis. 2017 Dec;23(12):2180-2188.

Cranston RD, Regueiro M, Hashash J, Baker JR, Richardson-Harman N, Janocko L, McGowan I. A Pilot Study of the Prevalence of Anal Human Papillomavirus and Dysplasia in a Cohort of Patients With IBD. Dis Colon Rectum. 2017 Dec;60(12):1307-1313.

Francis FF, Frye R, Hashash JG. Cholelithiasis and Biliary Cirrhosis in a 28-Year-Old Man. Clin Gastroenterol Hepatol. 2017 May;15(5):A31-A32.


Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz








Kathryn M. Albers, PhDSaloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Grown Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018 Aug;47(7):856-63.




56



Gavin E. Arteel, PhDKhoo NKH, Fazzari M, Chartoumpekis DV, Li L, Guimaraes DA, Arteel GE, Shiva S, Freeman BA. Electrophilic Nitro-oleic Acid Reverses Obesity-induced Hepatic Steatosis. Redox Biol. 2019 Apr;22:10132.

Poole LG, Beier JI, Torres-Gonzales E, Schlueter CF, Hudson SV, Artis A, Warner NL, Nguyen-Ho CT, Dolin CE, Ritzenthaler JD, Hoyle GW, Roman J, Arteel GE. Chronic + Binge Alcohol Exposure Promotes Inflammation and Alters Airway Mechanics in the Lung. Alcohol. 2018 Nov 14.

Lang AL, Chen L, Poff GD, Ding WX, Barnett RA, Arteel GE, Beier JI. Vinyl chloride dysregulates metabolic homeostasis and enhances diet-induced liver injury in mice. Hepatol Commun. 2018 Feb 9;2(3):270-284.

Hudson SV, Dolin CE, Poole LG, Massey VL, Wilkey D, Beier JI, Merchant ML, Frieboes HB, Arteel GE. Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins. Sci Rep. 2017 Sep 29;7(1):12444.

Poole LG, Massey VL, Siow DL, Torres-Gonzáles E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE. Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2017 Sep;57(3):315-323.

Massey VL, Dolin CE, Poole LG, Hudson SV, Siow DL, Brock GN, Merchant ML, Wilkey DW, Arteel GE. The hepatic "matrisome" responds dynamically to injury: Characterization of transitional changes to the extracellular matrix in mice. Hepatology. 2017 Mar;65(3):969-982.

Anders LC, Yeo H, Kaelin BR, Lang AL, Bushau AM, Douglas AN, Cave M, Arteel GE, McClain CJ, Beier JI. Role of dietary fatty acids in liver injury caused by vinyl chloride metabolites in mice. Toxicol Appl Pharmacol. 2016 Nov 15;311:34-41.

Schreiter T, Sowa JP, Schlattjan M, Treckmann J, Paul A, Strucksberg KH, Baba HA, Odenthal M, Gieseler RK, Gerken G, Arteel GE, Canbay A. Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage. Sci Rep. 2016 Aug 23;6:31916.

Beier JI, Guo L, Ritzenthaler JD, Joshi-Barve S, Roman J, Arteel GE. Fibrin-mediated integrin signaling plays a critical role in hepatic regeneration after partial hepatectomy in mice. Ann Hepatol. 2016 Sep-Oct;15(5):762-72.

Arthur M. Barrie III, MD, PhDAnderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz Md, Regueiro M, Binion. Low Rates of Dermatologic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-39.


Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 June;24(7):1380-88.




Anderson A, Click B, Ramos-Rivers C, Cheng D, Babichenko D, Koutroubakis IE, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Lasting Impact of Clostridium difficile Infection in Inflammatory Bowel Disease: A Propensity Score Matched Analysis. Inflamm Bowel Dis. 2017 Dec;23(12):2180-2188.



Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Development of an Inflammatory Bowel Disease Research Registry Derived from Observational Electronic Health Record Data for Comprehensive Clinical Phenotyping. Dig Dis Sci. 2016 Nov;61(11):3236-3245.




57



Gavin E. Arteel, PhDKhoo NKH, Fazzari M, Chartoumpekis DV, Li L, Guimaraes DA, Arteel GE, Shiva S, Freeman BA. Electrophilic Nitro-oleic Acid Reverses Obesity-induced Hepatic Steatosis. Redox Biol. 2019 Apr;22:10132.

Poole LG, Beier JI, Torres-Gonzales E, Schlueter CF, Hudson SV, Artis A, Warner NL, Nguyen-Ho CT, Dolin CE, Ritzenthaler JD, Hoyle GW, Roman J, Arteel GE. Chronic + Binge Alcohol Exposure Promotes Inflammation and Alters Airway Mechanics in the Lung. Alcohol. 2018 Nov 14.



Poole LG, Massey VL, Siow DL, Torres-Gonzáles E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE. Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2017 Sep;57(3):315-323.

Massey VL, Dolin CE, Poole LG, Hudson SV, Siow DL, Brock GN, Merchant ML, Wilkey DW, Arteel GE. The hepatic "matrisome" responds dynamically to injury: Characterization of transitional changes to the extracellular matrix in mice. Hepatology. 2017 Mar;65(3):969-982.


Schreiter T, Sowa JP, Schlattjan M, Treckmann J, Paul A, Strucksberg KH, Baba HA, Odenthal M, Gieseler RK, Gerken G, Arteel GE, Canbay A. Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage. Sci Rep. 2016 Aug 23;6:31916.


Arthur M. Barrie III, MD, PhDAnderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz Md, Regueiro M, Binion. Low Rates of Dermatologic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-39.


Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 June;24(7):1380-88.











58



Ramon Bataller Alberola, MD, PhDBarritt AS 4th, Jiang Y, Schmidt M, Hayashi PH, Bataller R. Charges for Alcoholic Cirrhosis Exceed All Other Etiologies of Cirrhosis Combined: A National and State Inpatient Survey Analysis. Dig Dis Sci. 2019 Jun;64(6):1460-1469.

Stärkel P, Schnabl B, Leclercq S, Komuta M, Bataller R, Argemi J, Palma E, Chokshi S, Hellerbrand C, Maccioni L, Lanthier N, Leclercq I. Deficient IL-6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis. Hepatol Commun. 2019 May 10;3(7):867-882.

Lang S, Duan Y, Liu J, Torralba MG, Kuelbs C, Ventura-Cots M, Abraldes JG, Bosques-Padilla F, Verna EC, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross D, Lucey MR, Louvet A, Mathurin P, Garcia-Tsao G, Ho SB, Tu XM, Bataller R, Stärkel P, Fouts DE, Schnabl B. Intestinal Fungal Dysbiosis and Systemic Immune Response to Fungi in Patients with Alcoholic Hepatitis. Hepatology. 2019 Jun 22.

Ventura-Cots M, Watts AE, Cruz-Lemini M, Shah ND, Ndugga N, McCan P, Barritt AS 4th, Jain A, Ravi S, Fernandez-Carrillo C, Abraldes JG, Altamirano J, Bataller R. Colder Weather and Fewer Sunlight Hours Increase Alcohol Consumption and Alcoholic Cirrhosis Worldwide. Hepatology. 2019 May;69(5):1916-30.

Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P. Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis. Hepatology. 2019 May;69(5):2180-2195.

Rachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patients with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.

Michelena J, Alonso C, Martínez-Arranz I, Altamirano J, Mayo R, Sancho-Bru P, Bataller R, Ginès P, Castro A, Caballería J. Metabolomics Discloses a New Non-invasive Method for the Diagnosis and Prognosis of Patients with Alcoholic Hepatitis. Ann Hepatol. 2019 Jan - Feb;18(1):144-154.

López-Pelayo H, Miquel L, Altamirano J, Bataller R, Caballeria J, Ortega L, Lligoña A, Gual A. Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse. J Psychosom Res. 2019 Jan;116:75-82.

Sujan R, Cruz-Lemini M, Altamirano J, Simonetto DA, Maiwall R, Axley P, Richardson T, Desai V, Cabezas J, Vargas V, Kamath PS, Shah VH, Sarin SK, Bataller R, Singal AK. A Validated Score Predicts Acute Kidney Injury and Survival in Patients with Alcoholic Hepatitis. Liver Transpl. 2018 Dec;24(12):1655-64.

Massey VL, Qin L, Cabezas J, Caballeria J, Sancho-Bru P, Bataller R, Crews FT. TLR7-let-7 Signaling Contribues to Ethanol-induced Hepatic Inflammatory Response in Mice and in Alcoholic Hepatitis. Alcohol Clin Exp Res. 2018 Nov;42(11):2107-22.

Kurniawan DW, Jajoriya AK, Dhawan G, Mishra D, Argemi J, Bataller R, Storm G, Mishra DP, Prakash J, Bansal R. Therapeutic Inhibition of Spleen Tyrosine Kinase in Inflammatory Macrophages Using PLGA Nanoparticles for the Treatment of Non-alcoholic Steatohepatitis. J Control Release. 2018 Oct 28;288:227-38.

Chen Y, Ouyang X, Hoque R, Garcia-Martinez I, Yousaf MN, Tonack S, Offermanns S, Dubuquoy L, Louvet A, Mathurin P, Massey V, Schnabl B, Bataller RA, Mehal WZ. -Hydroxybutyrate Protects from Alcohol-induced

Liver Injury via a Hcar2-cAMP Dependent Pathway. J Hepatol. 2018 Sep;69(3):687-96.

Brandl K, Hartmann P, Jih LJ, Pizzo DP, Argemi J, Ventura-Cots M, Coulter S, Liddle C, Ling L, Rossi SJ, DePaoli AM, loomba R, Mehal WZ, Fouts DE, Lucey MR, Bosques-Padilla F, Mathurin P, Louvet A, Garcia-Tsao G, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballeria J, Shawcross D, Starkel P, Ho SB, Bataller R, Schnabl B. Dysregulation of Serum Bile Acids and FGF19 in Alcoholic Hepatitis. J Hepatol. 2018 Aug;6992):396-405.

Khanova E, Wu R, Wang W, Yan R, Chen Y, French SW, Llorente C, Pan SQ, Yang Q, Li Y, Lazaro R, Ansong C, Smith RD, Bataller R, Morgan T, Schnabl B, Tsukamoto H. Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic Hepatitis in Mice and Patients. Hepatology. 2018 May;67(5):1737-1753.

Ouyang X, Han SN, Zhang JY, Dioletis E, Nemeth BT, Pacher P, Feng D, Bataller R, Cabezas J, Stärkel P, Caballeria J, Pongratz RL, Cai SY, Schnabl B, Hoque R, Chen Y, Yang WH, Garcia-Martinez I, Wang FS, Gao B, Torok NJ, Kibbey RG, Mehal WZ. Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1 Transactivation in Steatohepatitis. Cell Metab. 2018 Feb 6;27(2):339-350.e3.

Altamirano J, López-Pelayo H, Michelena J, Jones PD, Ortega L, Ginès P, Caballería J, Gual A, Bataller R, Lligoña A. Alcohol Abstinence in Patients Surviving an Episode of Alcoholic Hepatitis: Prediction and Impact on Long-Term Survival. Hepatology. 2017 Dec;66(6):1842-1853.

Jaideep Behari, MD, PhDCannella R, Borhani AA, Tublin M, Behari J, Furlan A. Diagnostic Value of MR-based Texture Analysis for the Assessment of Hepatic fibrosis in Patients with Nonalcoholic Fatty Liver Disease (NAFLD). Abdom Radiol (NY). 2019 May;44(5):1816-24.

Rachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patietns with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.

Rachakonda V, Wills R, DeLany JP, Kershaw EE, Behari J. Differential Impact of Weight Loss on Nonalcoholic Fatty Liver Resolution in a North American Cohort with Obesity. Obesity (Silver Spring). 2017 Aug;25(8):1360-1368.

Dunn MA, Josbeno DA, Tevar AD, Rachakonda V, Ganesh SR, Schmotzer AR, Kallenborn EA, Behari J, Landsittel DP, DiMartini AF, Delitto A. Frailty as Tested by Gait Speed Is an Independent Risk Factor for Cirrhosis Complications that Require Hospitalization. Am J Gastroenterol. 2016 Dec;111(12):1768-1775.

Rachakonda V, Borhani AA, Dunn MA, Andrzejewski M, Martin K, Behari J. Serum Leptin Is a Biomarker of Malnutrition in Decompensated Cirrhosis. PLoS One. 2016 Sep 1;11(9):e0159142.

Juliane I. Beier, PhDChen L, Lang AL, Poff GD, Ding WX, Beier JI. Vinyl Chloride-induced Interaction of Nonalcoholic and Toxicant-associated Steatohepatitis: Protection by the ALDH2 Activator Alda-1. Redox Biol. 2019 Apr 19;24:101205.

Poole LG, Beier JI, Torres-Gonzales E, Schlueter CF, Hudson SV, Artis A, Warner NL, Nguyen-Ho CT, Dolin CE, Ritzenthaler JD, Hoyle GW, Roman J, Arteel GE. Chronic + Binge Alcohol Exposure Promotes Inflammation

59



Ramon Bataller Alberola, MD, PhDBarritt AS 4th, Jiang Y, Schmidt M, Hayashi PH, Bataller R. Charges for Alcoholic Cirrhosis Exceed All Other Etiologies of Cirrhosis Combined: A National and State Inpatient Survey Analysis. Dig Dis Sci. 2019 Jun;64(6):1460-1469.

Stärkel P, Schnabl B, Leclercq S, Komuta M, Bataller R, Argemi J, Palma E, Chokshi S, Hellerbrand C, Maccioni L, Lanthier N, Leclercq I. Deficient IL-6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis. Hepatol Commun. 2019 May 10;3(7):867-882.

Lang S, Duan Y, Liu J, Torralba MG, Kuelbs C, Ventura-Cots M, Abraldes JG, Bosques-Padilla F, Verna EC, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross D, Lucey MR, Louvet A, Mathurin P, Garcia-Tsao G, Ho SB, Tu XM, Bataller R, Stärkel P, Fouts DE, Schnabl B. Intestinal Fungal Dysbiosis and Systemic Immune Response to Fungi in Patients with Alcoholic Hepatitis. Hepatology. 2019 Jun 22.

Ventura-Cots M, Watts AE, Cruz-Lemini M, Shah ND, Ndugga N, McCan P, Barritt AS 4th, Jain A, Ravi S, Fernandez-Carrillo C, Abraldes JG, Altamirano J, Bataller R. Colder Weather and Fewer Sunlight Hours Increase Alcohol Consumption and Alcoholic Cirrhosis Worldwide. Hepatology. 2019 May;69(5):1916-30.

Aguilar-Bravo B, Rodrigo-Torres D, Ariño S, Coll M, Pose E, Blaya D, Graupera I, Perea L, Vallverdú J, Rubio-Tomás T, Dubuquoy L, Armengol C, Lo Nigro A, Stärkel P, Mathurin P, Bataller R, Caballería J, José Lozano J, Ginès P, Sancho-Bru P. Ductular Reaction Cells Display an Inflammatory Profile and Recruit Neutrophils in Alcoholic Hepatitis. Hepatology. 2019 May;69(5):2180-2195.

Rachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patients with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.

Michelena J, Alonso C, Martínez-Arranz I, Altamirano J, Mayo R, Sancho-Bru P, Bataller R, Ginès P, Castro A, Caballería J. Metabolomics Discloses a New Non-invasive Method for the Diagnosis and Prognosis of Patients with Alcoholic Hepatitis. Ann Hepatol. 2019 Jan - Feb;18(1):144-154.

López-Pelayo H, Miquel L, Altamirano J, Bataller R, Caballeria J, Ortega L, Lligoña A, Gual A. Treatment retention in a specialized alcohol programme after an episode of alcoholic hepatitis: Impact on alcohol relapse. J Psychosom Res. 2019 Jan;116:75-82.

Sujan R, Cruz-Lemini M, Altamirano J, Simonetto DA, Maiwall R, Axley P, Richardson T, Desai V, Cabezas J, Vargas V, Kamath PS, Shah VH, Sarin SK, Bataller R, Singal AK. A Validated Score Predicts Acute Kidney Injury and Survival in Patients with Alcoholic Hepatitis. Liver Transpl. 2018 Dec;24(12):1655-64.

Massey VL, Qin L, Cabezas J, Caballeria J, Sancho-Bru P, Bataller R, Crews FT. TLR7-let-7 Signaling Contribues to Ethanol-induced Hepatic Inflammatory Response in Mice and in Alcoholic Hepatitis. Alcohol Clin Exp Res. 2018 Nov;42(11):2107-22.

Kurniawan DW, Jajoriya AK, Dhawan G, Mishra D, Argemi J, Bataller R, Storm G, Mishra DP, Prakash J, Bansal R. Therapeutic Inhibition of Spleen Tyrosine Kinase in Inflammatory Macrophages Using PLGA Nanoparticles for the Treatment of Non-alcoholic Steatohepatitis. J Control Release. 2018 Oct 28;288:227-38.

Chen Y, Ouyang X, Hoque R, Garcia-Martinez I, Yousaf MN, Tonack S, Offermanns S, Dubuquoy L, Louvet A, Mathurin P, Massey V, Schnabl B, Bataller RA, Mehal WZ. -Hydroxybutyrate Protects from Alcohol-induced

Liver Injury via a Hcar2-cAMP Dependent Pathway. J Hepatol. 2018 Sep;69(3):687-96.

Brandl K, Hartmann P, Jih LJ, Pizzo DP, Argemi J, Ventura-Cots M, Coulter S, Liddle C, Ling L, Rossi SJ, DePaoli AM, loomba R, Mehal WZ, Fouts DE, Lucey MR, Bosques-Padilla F, Mathurin P, Louvet A, Garcia-Tsao G, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballeria J, Shawcross D, Starkel P, Ho SB, Bataller R, Schnabl B. Dysregulation of Serum Bile Acids and FGF19 in Alcoholic Hepatitis. J Hepatol. 2018 Aug;6992):396-405.

Khanova E, Wu R, Wang W, Yan R, Chen Y, French SW, Llorente C, Pan SQ, Yang Q, Li Y, Lazaro R, Ansong C, Smith RD, Bataller R, Morgan T, Schnabl B, Tsukamoto H. Pyroptosis by Caspase11/4-Gasdermin-D Pathway in Alcoholic Hepatitis in Mice and Patients. Hepatology. 2018 May;67(5):1737-1753.

Ouyang X, Han SN, Zhang JY, Dioletis E, Nemeth BT, Pacher P, Feng D, Bataller R, Cabezas J, Stärkel P, Caballeria J, Pongratz RL, Cai SY, Schnabl B, Hoque R, Chen Y, Yang WH, Garcia-Martinez I, Wang FS, Gao B, Torok NJ, Kibbey RG, Mehal WZ. Digoxin Suppresses Pyruvate Kinase M2-Promoted HIF-1 Transactivation in Steatohepatitis. Cell Metab. 2018 Feb 6;27(2):339-350.e3.

Altamirano J, López-Pelayo H, Michelena J, Jones PD, Ortega L, Ginès P, Caballería J, Gual A, Bataller R, Lligoña A. Alcohol Abstinence in Patients Surviving an Episode of Alcoholic Hepatitis: Prediction and Impact on Long-Term Survival. Hepatology. 2017 Dec;66(6):1842-1853.

Jaideep Behari, MD, PhDCannella R, Borhani AA, Tublin M, Behari J, Furlan A. Diagnostic Value of MR-based Texture Analysis for the Assessment of Hepatic fibrosis in Patients with Nonalcoholic Fatty Liver Disease (NAFLD). Abdom Radiol (NY). 2019 May;44(5):1816-24.

Rachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patietns with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.




Juliane I. Beier, PhDChen L, Lang AL, Poff GD, Ding WX, Beier JI. Vinyl Chloride-induced Interaction of Nonalcoholic and Toxicant-associated Steatohepatitis: Protection by the ALDH2 Activator Alda-1. Redox Biol. 2019 Apr 19;24:101205.

Poole LG, Beier JI, Torres-Gonzales E, Schlueter CF, Hudson SV, Artis A, Warner NL, Nguyen-Ho CT, Dolin CE, Ritzenthaler JD, Hoyle GW, Roman J, Arteel GE. Chronic + Binge Alcohol Exposure Promotes Inflammation

60



and Alters Airway Mechanics in the Lung. Alcohol. 2018 Nov 14.

Liang Y, Lang AL, Zhang J, Chen J, Wang K, Chen L, Beier JI, Qian Y, Cai L. Exposure to Vinyl Chloride and Its Influence on Western Diet-Induced Cardiac Remodeling. Chem Res Toxicol. 2018 Jun 18;31(6):482-493.


Warner NL, Jokinen JD, Beier JI, Sokoloski KJ, Lukashevich IS. Mammarenaviral Infection Is Dependent on Directional Exposure to and Release from Polarized Intestinal Epithelia. Viruses. 2018 Feb 10;10(2).


Guardiola JJ, Beier JI, Falkner KC, Wheeler B, McClain CJ, Cave M. Occupational exposures at a polyvinyl chloride production facility are associated with significant changes to the plasma metabolome. Toxicol Appl Pharmacol. 2016 Dec 15;313:47-56.



David G. Binion, MDHashash JG, Vachon A, Ramos Rivers C, Regueiro MD, Binion DG, Altman L, Williams C, Szigethy E. Predictors of Suicidal ideation Among IBD Outpatients. J Clin Gastroenterol. 2019 Jan;53(1):e41-e45.


Anderson AJM, Ferris LK, Binion DG, Smith KJ. Cost-Effectiveness of Melanoma Screening in Inflammatory Bowel Disease. Dis Dis Sci. 2018 Oct;63(10):2564-72.

Chablani SV, Ramos-Rviers C, Binion DG, Szigethy E. Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2018 Sep;63(9):2482-84.

Hartman DJ, Binion DG, Regueiro MD, Miller C, Herbst C, Pai RK. Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation. Inflamm Bowel Dis. 2018 Jul 12;24(8):1780-90.


Johnson CM, Hartman DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Al Hashash J, Barrie A, Pfanner TP, Dunn M, Koutroubakis IE, Binion DG. Epithelioid Granulomas Associate With Increased Severity and Progression of Crohn's Disease, Based on 6-Year Follow-Up. Clin Gastroenterol Hepatol. 2018 Jun;16(6):900-907.e1.





Anderson A, Click B, Ramos-Rivers C, Cheng D, Babichenko D, Koutroubakis IE, Hashash JG, Schwartz M, Swoger J, Barrie AM 3rd, Dunn MA, Regueiro M, Binion DG. Lasting Impact of Clostridium difficile Infection in Inflammatory Bowel Disease: A Propensity Score Matched Analysis. Inflamm Bowel Dis. 2017 Dec;23(12):2180-2188..

Cruz RJ Jr, Butera L, Poloyac K, McGurgan J, Stein W, Binion D, Humar A. Surgical and Medical Approach to Patients Requiring Total Small Bowel Resection: Managing the "No Gut Syndrome". Surgery. 2017 Oct;162(4):871-879.

Iskandar H, Greer JB, Krasinskas AM, Tinsley AT, Koltun WA, Siegel CA, Levy LC, Herfarth HH, Farraye FA, Binion DG, Rosh JR, Keljo DJ, Isaacs KL, Regueiro MD. IBD LIVE Series-Case 8: Treatment Options for Refractory Esophageal Crohn's Disease and Hidradenitis Suppurativa. Inflamm Bowel Dis. 2017 Oct;23(10):1667-1677.

Click BH, Greer JB, Regueiro MD, Hartman DJ, Davis PL, Siegel CA, Herfarth HH, Rosh JR, Shah SA, Koltun WA, Binion DG, Baidoo L, Szigethy E. IBD LIVE Series-Case 7: The Brain-Gut Connection and the Importance of Integrated Care in IBD. Inflamm Bowel Dis. 2017 May;23(5):681-694.


Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz 61



and Alters Airway Mechanics in the Lung. Alcohol. 2018 Nov 14.

Liang Y, Lang AL, Zhang J, Chen J, Wang K, Chen L, Beier JI, Qian Y, Cai L. Exposure to Vinyl Chloride and Its Influence on Western Diet-Induced Cardiac Remodeling. Chem Res Toxicol. 2018 Jun 18;31(6):482-493.


Warner NL, Jokinen JD, Beier JI, Sokoloski KJ, Lukashevich IS. Mammarenaviral Infection Is Dependent on Directional Exposure to and Release from Polarized Intestinal Epithelia. Viruses. 2018 Feb 10;10(2).


Guardiola JJ, Beier JI, Falkner KC, Wheeler B, McClain CJ, Cave M. Occupational exposures at a polyvinyl chloride production facility are associated with significant changes to the plasma metabolome. Toxicol Appl Pharmacol. 2016 Dec 15;313:47-56.



David G. Binion, MDHashash JG, Vachon A, Ramos Rivers C, Regueiro MD, Binion DG, Altman L, Williams C, Szigethy E. Predictors of Suicidal ideation Among IBD Outpatients. J Clin Gastroenterol. 2019 Jan;53(1):e41-e45.


Anderson AJM, Ferris LK, Binion DG, Smith KJ. Cost-Effectiveness of Melanoma Screening in Inflammatory Bowel Disease. Dis Dis Sci. 2018 Oct;63(10):2564-72.

Chablani SV, Ramos-Rviers C, Binion DG, Szigethy E. Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2018 Sep;63(9):2482-84.

Hartman DJ, Binion DG, Regueiro MD, Miller C, Herbst C, Pai RK. Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation. Inflamm Bowel Dis. 2018 Jul 12;24(8):1780-90.


Johnson CM, Hartman DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Al Hashash J, Barrie A, Pfanner TP, Dunn M, Koutroubakis IE, Binion DG. Epithelioid Granulomas Associate With Increased Severity and Progression of Crohn's Disease, Based on 6-Year Follow-Up. Clin Gastroenterol Hepatol. 2018 Jun;16(6):900-907.e1.






Cruz RJ Jr, Butera L, Poloyac K, McGurgan J, Stein W, Binion D, Humar A. Surgical and Medical Approach to Patients Requiring Total Small Bowel Resection: Managing the "No Gut Syndrome". Surgery. 2017 Oct;162(4):871-879.




Anderson AJ, Click B, Ramos-Rivers C, Babichenko D, Koutroubakis IE, Hartman DJ, Hashash JG, Schwartz 62




Rajan D, Greer JB, Regueiro MD, Baidoo L, Binion DG, Herfarth HH, Siegel CA, Hartman DJ, Farraye FA, Koutroubakis IE, Brand MH, Williams ED, Goyal A, Cross RK. IBD LIVE Case Series-Case 6: Persistent Skin Lesions in a Patient with Crohn's Disease: You Hear Hoof Beats and Discover a Zebra. Inflamm Bowel Dis. 2016 Nov;22(11):2754-2764.


Kopylov U, Boucher G, Waterman M, Rivers CR, Patel M, Cho JH, Colombel JF, Duerr RH, Binion D, McGovern DP, Schumm PP, Brant SR, Silverberg MS, Rioux JD, Bitton A. Genetic Predictors of Benign Course of Ulcerative Colitis--A North American Inflammatory Bowel Disease Genetics Consortium Study. Inflamm Bowel Dis. 2016 Oct;22(10):2311-6.


Abdul-Baki H, Greer JB, Binion DG, Kermanshahi TR, Brand MH, Williams ED, Bensen SP, Holubar SD, Keljo DJ, Regueiro MD. IBD LIVE Case Series-Case 5: The Many Faces of Cytomegalovirus in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 Sep;22(9):2245-54.

Lee SD, Rubin DT, Sandborn WJ, Randall C, Younes Z, Schreiber S, Schwartz DA, Burakoff R, Binion D, Dassopoulos T, Arsenescu R, Gutierrez A, Scherl E, Kayhan C, Hasan I, Kosutic G, Spearman M, Sen D, Coarse J, Hanauer S. Reinduction with Certolizumab Pegol in Patients with Crohn's Disease Experiencing Disease Exacerbation: 7-Year Data from the PRECiSE 4 Study. Inflamm Bowel Dis. 2016 Aug;22(8):1870-80.



Randall E. Brand, MDGreer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD, Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract. 2019 Jun;34(3):387-399.

Muniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S,

Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.

Singhi AD, George B, Greenbowe JR, Chung J, Suh J, Maitra A, Klempner SJ, Hendifar A, Milind JM, Golan T, Brand RE, Zureikat AH, Roy S, Schrock AB, Miller VA, Ross JS, Ali SM, Bahary N. Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers. Gastroenterology. 2019 Jun;156(8):2242-2253.e4.

Staal B, Liu Y, Barnett D, Hsueh P, He Z, Gao C, Partyka K, Hurd MW, Singhi AD, Drake RR, Huang Y, Maitra A, Brand RE, Haab BB. The sTRA Plasma Biomarker: Blinded Validation of Improved Accuracy Over CA19-9 in Pancreatic Cancer Diagnosis.Clin Cancer Res. 2019 May 1;25(9):2745-2754.

Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10. [Epub ahead of print]

Jahan R, Ganguly K, Smith LM, Atri P, Carmicheal J, Sheinin Y, Rachagani S, Natarajan G, Brand RE, Macha MA, Grandgenett PM, Kaur S, Batra SK. Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer. EBioMedicine. 2019 Apr;42:375-385.

Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Troendle D, Tang G, Slivka A, Singh VK, Sherman S, Shah U, Sandhu BS, Romagnuolo J, Rhee S, Pohl JF, Perito ER, Ooi CY, Nathan JD, Muniraj T, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Lewis M, Husain SZ, Himes R, Heyman MB, Guda N, Gonska T, Giefer MJ, Gelrud A, Gariepy CE, Gardner TB, Freedman SD, Forsmark CE, Fishman DS, Cote GA, Conwell D, Brand RE, Bellin M, Barth B, Banks PA, Anderson MA, Amann ST, Alkaade S, Abu-El-Haija M, Abberbock JN, Lowe ME, Yadav D. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors. J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):566-573.

Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, Fabianova E, Holcatova I, Janout V, Feng Z, Yip-Schneider M, Zhang J, Brand R, Taguchi A, Maitra A, Brennan P, Max Schmidt C, Hanash S. A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2019 Apr 1;111(4):372-379.

Capello M, Vykoukal JV, Katayama H, Bantis LE, Wang H, Kundnani DL, Aguilar-Bonavides C, Aguilar M, Tripathi SC, Dhillon DS, Momin AA, Peters H, Katz MH, Alvarez H, Bernard V, Ferri-Borgogno S, Brand R, Adler DG, Firpo MA, Mulvihill SJ, Molldrem JJ, Feng Z, Taguchi A, Maitra A, Hanash SM. Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun. 2019 Jan 16;10(1):254.

Stoffel EM, McKernin SE, Brand R, Canto M, Goggins M, Moravek C, Nagarajan A, Petersen GM, Simeone DM, Yurgelun M, Khorana AA. Evaluating Susceptibility to Pancreatic Cancer: ASCO Provisional Clinical Opinion. J Clin Oncol. 2019 Jan 10;37(2):153-164.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat

63




Rajan D, Greer JB, Regueiro MD, Baidoo L, Binion DG, Herfarth HH, Siegel CA, Hartman DJ, Farraye FA, Koutroubakis IE, Brand MH, Williams ED, Goyal A, Cross RK. IBD LIVE Case Series-Case 6: Persistent Skin Lesions in a Patient with Crohn's Disease: You Hear Hoof Beats and Discover a Zebra. Inflamm Bowel Dis. 2016 Nov;22(11):2754-2764.


Kopylov U, Boucher G, Waterman M, Rivers CR, Patel M, Cho JH, Colombel JF, Duerr RH, Binion D, McGovern DP, Schumm PP, Brant SR, Silverberg MS, Rioux JD, Bitton A. Genetic Predictors of Benign Course of Ulcerative Colitis--A North American Inflammatory Bowel Disease Genetics Consortium Study. Inflamm Bowel Dis. 2016 Oct;22(10):2311-6.



Lee SD, Rubin DT, Sandborn WJ, Randall C, Younes Z, Schreiber S, Schwartz DA, Burakoff R, Binion D, Dassopoulos T, Arsenescu R, Gutierrez A, Scherl E, Kayhan C, Hasan I, Kosutic G, Spearman M, Sen D, Coarse J, Hanauer S. Reinduction with Certolizumab Pegol in Patients with Crohn's Disease Experiencing Disease Exacerbation: 7-Year Data from the PRECiSE 4 Study. Inflamm Bowel Dis. 2016 Aug;22(8):1870-80.



Randall E. Brand, MDGreer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD, Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract. 2019 Jun;34(3):387-399.

Muniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S,

Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.

Singhi AD, George B, Greenbowe JR, Chung J, Suh J, Maitra A, Klempner SJ, Hendifar A, Milind JM, Golan T, Brand RE, Zureikat AH, Roy S, Schrock AB, Miller VA, Ross JS, Ali SM, Bahary N. Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers. Gastroenterology. 2019 Jun;156(8):2242-2253.e4.

Staal B, Liu Y, Barnett D, Hsueh P, He Z, Gao C, Partyka K, Hurd MW, Singhi AD, Drake RR, Huang Y, Maitra A, Brand RE, Haab BB. The sTRA Plasma Biomarker: Blinded Validation of Improved Accuracy Over CA19-9 in Pancreatic Cancer Diagnosis.Clin Cancer Res. 2019 May 1;25(9):2745-2754.

Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10. [Epub ahead of print]

Jahan R, Ganguly K, Smith LM, Atri P, Carmicheal J, Sheinin Y, Rachagani S, Natarajan G, Brand RE, Macha MA, Grandgenett PM, Kaur S, Batra SK. Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer. EBioMedicine. 2019 Apr;42:375-385.


Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, Fabianova E, Holcatova I, Janout V, Feng Z, Yip-Schneider M, Zhang J, Brand R, Taguchi A, Maitra A, Brennan P, Max Schmidt C, Hanash S. A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2019 Apr 1;111(4):372-379.

Capello M, Vykoukal JV, Katayama H, Bantis LE, Wang H, Kundnani DL, Aguilar-Bonavides C, Aguilar M, Tripathi SC, Dhillon DS, Momin AA, Peters H, Katz MH, Alvarez H, Bernard V, Ferri-Borgogno S, Brand R, Adler DG, Firpo MA, Mulvihill SJ, Molldrem JJ, Feng Z, Taguchi A, Maitra A, Hanash SM. Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun. 2019 Jan 16;10(1):254.

Stoffel EM, McKernin SE, Brand R, Canto M, Goggins M, Moravek C, Nagarajan A, Petersen GM, Simeone DM, Yurgelun M, Khorana AA. Evaluating Susceptibility to Pancreatic Cancer: ASCO Provisional Clinical Opinion. J Clin Oncol. 2019 Jan 10;37(2):153-164.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat

64



AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Brand RM, Biswas N, Siegel A, Myerski A, Engstrom J, Jeffrey Metter E, Brand RE, Cranston RD, McGowan I. Immunological responsiveness of intestinal tissue explants and mucosal mononuclear cells to ex vivo stimulation. J Immunol Methods. 2018 Dec;463:39-46.

Maitra A, Sharma A, Brand RE, Van Den Eeden SK, Fisher WE, Hart PA, Hughes SJ, Mather KJ, Pandol SJ, Park WG, Feng Z, Serrano J, Rinaudo JAS, Srivastava S, Chari ST; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1244-1248.

Phillips AE, Shah N, Borhani AA, Yadav D, Brand RE. Prior History of Pancreatitis Accelerates the Development of Pancreatic Adenocarcinoma. Pancreas. 2018 Nov/Dec;47(10):1262-1266.

Brand R, Borazanci E, Speare V, Dudley B, Karloski E, Peters MLB, Stobie L, Bahary N, Zeh H, Zureikat A, Hogg M, Lee K, Tsung A, Rhee J, Ohr J, Sun W, Lee J, Moser AJ, DeLeonardis K, Krejdovsky J, Dalton E, LaDuca H, Dolinsky J, Colvin A, Lim C, Black MH, Tung N. Prospective study of germline genetic testing in incident cases of pancreatic adenocarcinoma. Cancer. 2018 Sep 1;124(17):3520-3527.

Brand RM, Siegel A, Myerski A, Metter EJ, Engstrom J, Brand RE, Squiquera L, Hodge T, Sulley J, Cranston RD, McGowan I. Ranpirnase Reduces HIV-1 Infection and Associated Inflammatory Changes in a Human Colorectal Explant Model. AIDS Res Hum Retroviruses. 2018 Oct;34(10):838-848.

Pai RK, Dudley B, Karloski E, Brand RE, O'Callaghan N, Rosty C, Buchanan DD, Jenkins MA, Thibodeau SN, French AJ, Lindor NM, Pai RK. DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome. Mod Pathol. 2018 Oct;31(10):1608-1618.

Zhan W, Shelton CA, Greer PJ, Brand RE, Whitcomb DC. Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts. Pancreas. 2018 Sep;47(8):924-936.

Chao DT, Shah NH, Zeh HJ 3rd, Singhi AD, Bahary N, McGrath KM, Fasanella KE, Zureikat AH, Whitcomb DC, Brand RE. Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age. Gastroenterol Res Pract. 2018 Jun 5;2018:2380596.

Coté GA, Yadav D, Abberbock JA, Whitcomb DC, Sherman S, Sandhu BS, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Guda NM, Muniraj T, Tang G, Brand R, Gelrud A, Amann ST, Forsmark CE, Wilcox MC, Slivka A, Gardner TB. Recurrent Acute Pancreatitis Significantly Reduces Quality of Life Even in the Absence of Overt Chronic Pancreatitis. Am J Gastroenterol. 2018 Jun;113(6):906-912.

Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology. 2018 Jun;154(8):2060-2063.e8.

Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D. Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African

ancestry. Pancreatology. 2018 May 19.

Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M. Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4767-4772.

Dudley B, Karloski E, Monzon FA, Singhi AD, Lincoln SE, Bahary N, Brand RE. Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy. Cancer. 2018 Apr 15;124(8):1691-1700.


Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia. Gut. 2018 Dec;67(12):2131-2141.

Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA, Maitra A, Hanash SM, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10202-10207.

Bellin MD, Whitcomb DC, Abberbock J, Sherman S, Sandhu BS, Gardner TB, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Cote GA, Guda NM, Muniraj T, Tang G, Brand RE, Gelrud A, Amann ST, Forsmark CE, Wilcox CM, Slivka A, Yadav D. Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States. Am J Gastroenterol. 2017 Sep;112(9):1457-1465.

Nigjeh EN, Chen R, Allen-Tamura Y, Brand RE, Brentnall TA, Pan S. Spectral library-based glycopeptide analysis-detection of circulating galectin-3 binding protein in pancreatic cancer. Proteomics Clin Appl. 2017 Sep;11(9-10).

Conwell DL, Banks PA, Sandhu BS, Sherman S, Al-Kaade S, Gardner TB, Anderson MA, Wilcox CM, Lewis MD, Muniraj T, Forsmark CE, Cote GA, Guda NM, Tian Y, Romagnuolo J, Wisniewski SR, Brand R, Gelrud A, Slivka A, Whitcomb DC, Yadav D. Validation of Demographics, Etiology, and Risk Factors for Chronic Pancreatitis in the USA: A Report of the North American Pancreas Study (NAPS) Group. Dig Dis Sci. 2017 Aug;62(8):2133-2140.

Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS. Global Protease Activity Profiling Provides

65



AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.


Maitra A, Sharma A, Brand RE, Van Den Eeden SK, Fisher WE, Hart PA, Hughes SJ, Mather KJ, Pandol SJ, Park WG, Feng Z, Serrano J, Rinaudo JAS, Srivastava S, Chari ST; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1244-1248.


Brand R, Borazanci E, Speare V, Dudley B, Karloski E, Peters MLB, Stobie L, Bahary N, Zeh H, Zureikat A, Hogg M, Lee K, Tsung A, Rhee J, Ohr J, Sun W, Lee J, Moser AJ, DeLeonardis K, Krejdovsky J, Dalton E, LaDuca H, Dolinsky J, Colvin A, Lim C, Black MH, Tung N. Prospective study of germline genetic testing in incident cases of pancreatic adenocarcinoma. Cancer. 2018 Sep 1;124(17):3520-3527.


Pai RK, Dudley B, Karloski E, Brand RE, O'Callaghan N, Rosty C, Buchanan DD, Jenkins MA, Thibodeau SN, French AJ, Lindor NM, Pai RK. DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome. Mod Pathol. 2018 Oct;31(10):1608-1618.





Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D. Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African

ancestry. Pancreatology. 2018 May 19.

Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M. Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4767-4772.

Dudley B, Karloski E, Monzon FA, Singhi AD, Lincoln SE, Bahary N, Brand RE. Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy. Cancer. 2018 Apr 15;124(8):1691-1700.



Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA, Maitra A, Hanash SM, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10202-10207.


Nigjeh EN, Chen R, Allen-Tamura Y, Brand RE, Brentnall TA, Pan S. Spectral library-based glycopeptide analysis-detection of circulating galectin-3 binding protein in pancreatic cancer. Proteomics Clin Appl. 2017 Sep;11(9-10).


Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider MT, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim GE, O'Donoghue AJ, Kirkwood KS, Craik CS. Global Protease Activity Profiling Provides

66



Differential Diagnosis of Pancreatic Cysts. Clin Cancer Res. 2017 Aug 15;23(16):4865-4874.

Balasenthil S, Huang Y, Liu S, Marsh T, Chen J, Stass SA, KuKuruga D, Brand R, Chen N, Frazier ML, Jack Lee J, Srivastava S, Sen S, McNeill Killary A. A Plasma Biomarker Panel to Identify Surgically Resectable Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 Aug 1;109(8).

Chiu WK, Brand RM, Camp D, Edick S, Mitchell C, Karas S, Zehmisch A, Ho K, Brand RE, Harrison J, Abo S, Cranston RD, McGowan I. The Safety of Multiple Flexible Sigmoidoscopies with Mucosal Biopsies in Healthy Clinical Trial Participants. AIDS Res Hum Retroviruses. 2017 Aug;33(8):820-826.

Xia M, Singhi AD, Dudley B, Brand R, Nikiforova M, Pai RK. Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency. Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):399-406.

Barnett D, Liu Y, Partyka K, Huang Y, Tang H, Hostetter G, Brand RE, Singhi AD, Drake RR, Haab BB. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Sci Rep. 2017 Jun 22;7(1):4020.

Kuan SF, Ren B, Brand R, Dudley B, Pai RK. Neoadjuvant therapy in microsatellite-stable colorectal carcinoma induces concomitant loss of MSH6 and Ki-67 expression. Hum Pathol. 2017 May;63:33-39.

Capello M, Bantis LE, Scelo G, Zhao Y, Li P, Dhillon DS, Patel NJ, Kundnani DL, Wang H, Abbruzzese JL, Maitra A, Tempero MA, Brand R, Firpo MA, Mulvihill SJ, Katz MH, Brennan P, Feng Z, Taguchi A, Hanash SM. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 Apr 1;109(4).

Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D. Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/ Unemployment, Current Smoking, and Associated Co-Morbidities. Am J Gastroenterol. 2017 Apr;112(4):633-642.

Nigjeh EN, Chen R, Brand RE, Petersen GM, Chari ST, von Haller PD, Eng JK, Feng Z, Yan Q, Brentnall TA, Pan S. Quantitative Proteomics Based on Optimized Data-Independent Acquisition in Plasma Analysis. J Proteome Res. 2017 Feb 3;16(2):665-676.

Kaur S, Smith LM, Patel A, Menning M, Watley DC, Malik SS, Krishn SR, Mallya K, Aithal A, Sasson AR, Johansson SL, Jain M, Singh S, Guha S, Are C, Raimondo M, Hollingsworth MA, Brand RE, Batra SK. A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. Am J Gastroenterol. 2017 Jan;112(1):172-183.

Singhi AD, Liu TC, Roncaioli JL, Cao D, Zeh HJ, Zureikat AH, Tsung A, Marsh JW, Lee KK, Hogg ME, Bahary N, Brand RE, McGrath KM, Slivka A, Cressman KL, Fuhrer K, O'Sullivan RJ. Alternative Lengthening of Telomeres and Loss of DAXX/ATRX Expression Predicts Metastatic Disease and Poor Survival in Patients with Pancreatic Neuroendocrine Tumors. Clin Cancer Res. 2017 Jan 15;23(2):600-609.

Sinha J, Cao Z, Dai J, Tang H, Partyka K, Hostetter G, Simeone DM, Feng Z, Allen PJ, Brand RE, Haab BB. A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas. PLoS One. 2016 Dec 19;11(12):e0167070.

Reatini BS, Ensink E, Liau B, Sinha JY, Powers TW, Partyka K, Bern M, Brand RE, Rudd PM, Kletter D, Drake R,

Haab BB. Characterizing Protein Glycosylation through On-Chip Glycan Modification and Probing. Anal Chem. 2016 Dec 6;88(23):11584-11592.

Wilcox CM, Sandhu BS, Singh V, Gelrud A, Abberbock JN, Sherman S, Cote GA, Al-Kaade S, Anderson MA, Gardner TB, Lewis MD, Forsmark CE, Guda NM, Romagnuolo J, Baillie J, Amann ST, Muniraj T, Tang G, Conwell DL, Banks PA, Brand RE, Slivka A, Whitcomb D, Yadav D. Racial Differences in the Clinical Profile, Causes, and Outcome of Chronic Pancreatitis. Am J Gastroenterol. 2016 Oct;111(10):1488-1496.

Farchoukh L, Kuan SF, Dudley B, Brand R, Nikiforova M, Pai RK. MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas. Am J Surg Pathol. 2016 Oct;40(10):1390-9.

Joshi S, Cruz E, Rachagani S, Guha S, Brand RE, Ponnusamy MP, Kumar S, Batra SK. Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer. Mol Oncol. 2016 Aug;10(7):1063-77.

Chen J, Wu X, Huang Y, Chen W, Brand RE, Killary AM, Sen S, Frazier ML. Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets. Oncotarget. 2016 Aug 30;7(35):56480-56490.

Romagnuolo J, Talluri J, Kennard E, Sandhu BS, Sherman S, Cote GA, Al-Kaade S, Gardner TB, Gelrud A, Lewis MD, Forsmark CE, Guda NM, Conwell DL, Banks PA, Muniraj T, Wisniewski SR, Tian Y, Wilcox CM, Anderson MA, Brand RE, Slivka A, Whitcomb DC, Yadav D. Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women: Analysis of a Large Multicenter Cohort. Pancreas. 2016 Aug;45(7):934-40.


Rhonda M. Brand, PhDMyerski A, Siegel A, Engstrom J, McGowan I, Brand RM. The Use of Droplet Digital PCR to Quantify HIV-1 Replication in the Colorectal Explant Model. AIDS Res Hum Retroviruses. 2019 Mar;35(3):326-334.

McGowan I, Wilkin T, Landovitz RJ, Wu C, Chen Y, Marzinke MA, Hendrix CW, Richardson P, Eshleman SH, Andrade A, Chege W, Anderson PL, McCauley M, Farley J, Mayer KH, Anton P, Brand RM, Cranston RD, Gulick R. The pharmacokinetics, pharmacodynamics, and mucosal responses to maraviroc-containing pre-exposure prophylaxis regimens in MSM. AIDS. 2019 Feb 1;33(2):237-246.



Epperly MW, Wipf P, Fisher R, Franicola D, Beumer J, Li S, Brand RM, Falo LD Jr, Erdos G, Greenberger JS. Evaluation of Different Formulations and Routes for the Delivery of the Ionizing Radiation Mitigator GS-

67



Differential Diagnosis of Pancreatic Cysts. Clin Cancer Res. 2017 Aug 15;23(16):4865-4874.

Balasenthil S, Huang Y, Liu S, Marsh T, Chen J, Stass SA, KuKuruga D, Brand R, Chen N, Frazier ML, Jack Lee J, Srivastava S, Sen S, McNeill Killary A. A Plasma Biomarker Panel to Identify Surgically Resectable Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 Aug 1;109(8).


Xia M, Singhi AD, Dudley B, Brand R, Nikiforova M, Pai RK. Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency. Appl Immunohistochem Mol Morphol. 2017 Jul;25(6):399-406.

Barnett D, Liu Y, Partyka K, Huang Y, Tang H, Hostetter G, Brand RE, Singhi AD, Drake RR, Haab BB. The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells. Sci Rep. 2017 Jun 22;7(1):4020.

Kuan SF, Ren B, Brand R, Dudley B, Pai RK. Neoadjuvant therapy in microsatellite-stable colorectal carcinoma induces concomitant loss of MSH6 and Ki-67 expression. Hum Pathol. 2017 May;63:33-39.

Capello M, Bantis LE, Scelo G, Zhao Y, Li P, Dhillon DS, Patel NJ, Kundnani DL, Wang H, Abbruzzese JL, Maitra A, Tempero MA, Brand R, Firpo MA, Mulvihill SJ, Katz MH, Brennan P, Feng Z, Taguchi A, Hanash SM. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 Apr 1;109(4).


Nigjeh EN, Chen R, Brand RE, Petersen GM, Chari ST, von Haller PD, Eng JK, Feng Z, Yan Q, Brentnall TA, Pan S. Quantitative Proteomics Based on Optimized Data-Independent Acquisition in Plasma Analysis. J Proteome Res. 2017 Feb 3;16(2):665-676.

Kaur S, Smith LM, Patel A, Menning M, Watley DC, Malik SS, Krishn SR, Mallya K, Aithal A, Sasson AR, Johansson SL, Jain M, Singh S, Guha S, Are C, Raimondo M, Hollingsworth MA, Brand RE, Batra SK. A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. Am J Gastroenterol. 2017 Jan;112(1):172-183.


Sinha J, Cao Z, Dai J, Tang H, Partyka K, Hostetter G, Simeone DM, Feng Z, Allen PJ, Brand RE, Haab BB. A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas. PLoS One. 2016 Dec 19;11(12):e0167070.

Reatini BS, Ensink E, Liau B, Sinha JY, Powers TW, Partyka K, Bern M, Brand RE, Rudd PM, Kletter D, Drake R,

Haab BB. Characterizing Protein Glycosylation through On-Chip Glycan Modification and Probing. Anal Chem. 2016 Dec 6;88(23):11584-11592.


Farchoukh L, Kuan SF, Dudley B, Brand R, Nikiforova M, Pai RK. MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas. Am J Surg Pathol. 2016 Oct;40(10):1390-9.

Joshi S, Cruz E, Rachagani S, Guha S, Brand RE, Ponnusamy MP, Kumar S, Batra SK. Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer. Mol Oncol. 2016 Aug;10(7):1063-77.

Chen J, Wu X, Huang Y, Chen W, Brand RE, Killary AM, Sen S, Frazier ML. Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets. Oncotarget. 2016 Aug 30;7(35):56480-56490.



Rhonda M. Brand, PhDMyerski A, Siegel A, Engstrom J, McGowan I, Brand RM. The Use of Droplet Digital PCR to Quantify HIV-1 Replication in the Colorectal Explant Model. AIDS Res Hum Retroviruses. 2019 Mar;35(3):326-334.

McGowan I, Wilkin T, Landovitz RJ, Wu C, Chen Y, Marzinke MA, Hendrix CW, Richardson P, Eshleman SH, Andrade A, Chege W, Anderson PL, McCauley M, Farley J, Mayer KH, Anton P, Brand RM, Cranston RD, Gulick R. The pharmacokinetics, pharmacodynamics, and mucosal responses to maraviroc-containing pre-exposure prophylaxis regimens in MSM. AIDS. 2019 Feb 1;33(2):237-246.



Epperly MW, Wipf P, Fisher R, Franicola D, Beumer J, Li S, Brand RM, Falo LD Jr, Erdos G, Greenberger JS. Evaluation of Different Formulations and Routes for the Delivery of the Ionizing Radiation Mitigator GS-

68



Nitroxide (JP4-039). In Vivo. 2018 Sep-Oct;32(5):1009-1023.

Cranston RD, Baker JR, Siegel A, Brand RM, Janocko L, McGowan I. A Pilot Study of the Immunologic, Virologic, and Pathologic Consequences of Intra-anal 5% Imiquimod in HIV-1-Infected Men With High-Grade Squamous Intraepithelial Lesions. Dis Colon Rectum. 2018 Mar;61(3):298-305.


Brand RM, Epperly MW, Stottlemyer JM, Skoda EM, Gao X, Li S, Huq S, Wipf P, Kagan VE, Greenberger JS, Falo LD Jr. A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage. J Invest Dermatol. 2017 Mar;137(3):576-586.

McGowan I, Dezzutti CS, Siegel A, Engstrom J, Nikiforov A, Duffill K, Shetler C, Richardson-Harman N, Abebe K, Back D, Else L, Egan D, Khoo S, Egan JE, Stall R, Williams PE, Rehman KK, Adler A, Brand RM, Chen B, Achilles S, Cranston RD. Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment. Lancet HIV. 2016 Dec;3(12):e569-e578.

Jennifer S. Chennat, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures, Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Brown JB, Pai RK, Burgess MA, Chennat J, Zureikat AH, Pathologic complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib, J Natl Compr Canc Netw, 2018 Dec;16(12):1424-28.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classificattion and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade Dysplasia Diagnosis Ratio and Progression Metrics Identify Variable Barrett's Esophagus Risk Stratification Proficiency in Independent Pathology Practices. Gastrointest Endosc. 2018 Nov;88(5):807-815.e2.


Cosgrove N, Siddiqui AA, Adler DG, Shahid H, Sarkar A, Sharma A, Kowalski TE, Loren D, Warndorf M, Chennat J, Munigala S, Papachristou GI. A Comparison of Bilateral Side-by-Side Metal Stents Deployed Above and Across the Sphincter of Oddi in the Management of Malignant Hilar Biliary Obstruction. J Clin Gastroenterol. 2017 Jul;51(6):528-533.

Vipperla K, Somerville C, Furlan A, Koutrompakis E, Saul M, Chennat J, Rabinovitz M, Whitcomb DC, Slivka A, Papachristou GI, Yadav D. Clinical Profile and Natural Course in a Large Cohort of Patients with Hypertriglyceridemia and Pancreatitis. J Clin Gastroenterol. 2017 Jan;51(1):77-85.

Umapathy C, Raina A, Saligram S, Tang T, Papachristou GI, Rabinovitz M, Chennat J, Zeh H, Zureikat AH, Hogg M, Lee KK, Saul MI, Whitcomb DC, Slivka A, Yadav D. Natural History after Acute Necrotizing Pancreatitis: A Large US Tertiary Care Experience. J Gastrointest Surg. 2016 Nov;20(11):1844-1853.

Kapil B. Chopra, MDPourtaheri N, Wang D, Calva D, Chopra K, Kumar AR. Adipofascial Flaps with Acellular Dermal Matrix Compared with Myocutaneous Flap Reconstruction in Lumbar Myelomeningocele Defects. J Craniofac Surg. 2018 May 10;29(5):1137-1142.

Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F, Teufel A, Laudes M, Lieb W, Jacobs G, Beuers U, Weersma RK, Wijmenga C, Marschall HU, Milkiewicz P, Pares A, Kontula K, Chazouillères O, Invernizzi P, Goode E, Spiess K, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, Floreani A, Gulamhusein AF, Eaton JE, Schreiber S, Coltescu C, Bowlus CL, Luketic VA, Odin JA, Chopra KB, Kowdley KV, Chalasani N, Manns MP, Srivastava B, Mells G, Sandford RN, Alexander G, Gaffney DJ, Chapman RW, Hirschfield GM, de Andrade M; UK-PSC Consortium; International IBD Genetics Consortium; International PSC Study Group, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, Anderson CA. Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Nat Genet. 2017 Feb;49(2):269-273.

Chu AS, Chopra KB, Perlmutter DH. Is severe progressive liver disease caused by alpha-1-antitrypsin deficiency more common in children or adults? Liver Transpl. 2016 Jul;22(7):886-94.

Rohit Das, MDSinghi Ad, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Das R, Zeh H, Zureikat A, Slivka A, Papachristou GI. Endoscopic Ultrasound-guided Creation of a Gastrogastric Conduit After Pancreaticoduodenectomy in a Patient with Prior Roux-en-Y Gastric Bypass. ACG Case Rep J. 2018 Dec 19;e100.

Das R, Clarke B, Tang G, Papachristou GI, Whitcomb DC, Slivka A, Yadav D. Endoscopic sphincterotomy (ES)

69



Nitroxide (JP4-039). In Vivo. 2018 Sep-Oct;32(5):1009-1023.

Cranston RD, Baker JR, Siegel A, Brand RM, Janocko L, McGowan I. A Pilot Study of the Immunologic, Virologic, and Pathologic Consequences of Intra-anal 5% Imiquimod in HIV-1-Infected Men With High-Grade Squamous Intraepithelial Lesions. Dis Colon Rectum. 2018 Mar;61(3):298-305.


Brand RM, Epperly MW, Stottlemyer JM, Skoda EM, Gao X, Li S, Huq S, Wipf P, Kagan VE, Greenberger JS, Falo LD Jr. A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage. J Invest Dermatol. 2017 Mar;137(3):576-586.

McGowan I, Dezzutti CS, Siegel A, Engstrom J, Nikiforov A, Duffill K, Shetler C, Richardson-Harman N, Abebe K, Back D, Else L, Egan D, Khoo S, Egan JE, Stall R, Williams PE, Rehman KK, Adler A, Brand RM, Chen B, Achilles S, Cranston RD. Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment. Lancet HIV. 2016 Dec;3(12):e569-e578.

Jennifer S. Chennat, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures, Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Brown JB, Pai RK, Burgess MA, Chennat J, Zureikat AH, Pathologic complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib, J Natl Compr Canc Netw, 2018 Dec;16(12):1424-28.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classificattion and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade Dysplasia Diagnosis Ratio and Progression Metrics Identify Variable Barrett's Esophagus Risk Stratification Proficiency in Independent Pathology Practices. Gastrointest Endosc. 2018 Nov;88(5):807-815.e2.




Umapathy C, Raina A, Saligram S, Tang T, Papachristou GI, Rabinovitz M, Chennat J, Zeh H, Zureikat AH, Hogg M, Lee KK, Saul MI, Whitcomb DC, Slivka A, Yadav D. Natural History after Acute Necrotizing Pancreatitis: A Large US Tertiary Care Experience. J Gastrointest Surg. 2016 Nov;20(11):1844-1853.

Kapil B. Chopra, MDPourtaheri N, Wang D, Calva D, Chopra K, Kumar AR. Adipofascial Flaps with Acellular Dermal Matrix Compared with Myocutaneous Flap Reconstruction in Lumbar Myelomeningocele Defects. J Craniofac Surg. 2018 May 10;29(5):1137-1142.

Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F, Teufel A, Laudes M, Lieb W, Jacobs G, Beuers U, Weersma RK, Wijmenga C, Marschall HU, Milkiewicz P, Pares A, Kontula K, Chazouillères O, Invernizzi P, Goode E, Spiess K, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J, Floreani A, Gulamhusein AF, Eaton JE, Schreiber S, Coltescu C, Bowlus CL, Luketic VA, Odin JA, Chopra KB, Kowdley KV, Chalasani N, Manns MP, Srivastava B, Mells G, Sandford RN, Alexander G, Gaffney DJ, Chapman RW, Hirschfield GM, de Andrade M; UK-PSC Consortium; International IBD Genetics Consortium; International PSC Study Group, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, Anderson CA. Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Nat Genet. 2017 Feb;49(2):269-273.

Chu AS, Chopra KB, Perlmutter DH. Is severe progressive liver disease caused by alpha-1-antitrypsin deficiency more common in children or adults? Liver Transpl. 2016 Jul;22(7):886-94.

Rohit Das, MDSinghi Ad, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Das R, Zeh H, Zureikat A, Slivka A, Papachristou GI. Endoscopic Ultrasound-guided Creation of a Gastrogastric Conduit After Pancreaticoduodenectomy in a Patient with Prior Roux-en-Y Gastric Bypass. ACG Case Rep J. 2018 Dec 19;e100.

Das R, Clarke B, Tang G, Papachristou GI, Whitcomb DC, Slivka A, Yadav D. Endoscopic sphincterotomy (ES)

70



may not alter the natural history of idiopathic recurrent acute pancreatitis (IRAP). Pancreatology. 2016 Sep-Oct;16(5):770-7.

Brian M. Davis, PhDSnyder LM, Chiang MC, Loeza-Alcocer E, Omori &, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE. Kappa Opioid Receptor Distribution and Function in Primary Afferents. Neuron. 2018 Sep 19;99(6):1274-88.

Saloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Grown Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018 Aug;47(7):856-63.




Smith-Edwards KM, DeBerry JJ, Saloman JL, Davis BM, Woodbury CJ. Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators. Elife. 2016 Nov 2;5.

Saloman JL, Scheff NN, Snyder LM, Ross SE, Davis BM, Gold MS. Gi-DREADD Expression in Peripheral Nerves Produces Ligand-Dependent Analgesia, as well as Ligand-Independent Functional Changes in Sensory Neurons. J Neurosci. 2016 Oct 19;36(42):10769-10781.

Andres Duarte-Rojo, MD, MS, DScSiongal AG, Rich NE, Mehta N, Branch A, Pilai A, Hoteit M, Volk M, Odewole M, Scaglione S, Guy J, Said A, Feld JJ, John BV, Frenette C, Mantry P, Rangnekar AS, Oloruntoba O, Leise M, Jou JH, Bhamidimarri KR, Kulik L, Tran T, Samant H. Dhanasekaran R, Duarte-Rojo A, Salgia R, Eswaran S, Jalal P, Flores A, Satapathy SK, Wong R, Huang A, Misra S, Schwartz M, Mitrani R, Nakka S, Noureddine W, Ho C, Konjeti VR, Dao A, Nelson K, Delarose K, Rahim U, Mavuram M, Xie JJ, Murphy CC, Parikh ND. Direct-acting Antiviral Theraphy Not Associate with Recurrence of Hepatocellular Carcinoma in a Multicenter North American Cohort Study. Gastroenterology. 2019 May;156(6):1683-92.

Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL. Frailty Associated with Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study. Gastroenterolgy. 2019 May;156(6):1675-82.

Smeets XJNM, Knoester I, Grooteman KV, Singh VK, Banks PA, Papachristou GI, Duarte-Rojo A, Robles-Diaz G, Kievit W, Besselink MGH, Verdonk RC, Van Santvoort HC, Drenth JPH, Belias M, Van Geenen EJM, Eutch

Pancreatitis Study Group. The Associate Between Obesity and Outcomes in Acute Pancreatitis: An Individual Patient Data Meta-analysis. Eur J Gastroenterol Hepatol. 2019 Mar;31(3):316-22.

Duarte-Rojo A, Allampati S, Thacker LR, Flud CR, Patidar KR, White MB, Klair JS, Heuman DM, Wade JB, Gavis EA, Bajaj JS. Diagnosis of Covert Hepatic Encephalopahy: A Multi-center Study Testing the Utility of Single Versus Combined Testing. Metab Brain Dis. 2019 Feb;34(1):289-95.

Addepally NS, George N, Martinez-Macias R, Garcia-Saenz-de-Sicilia M, Kim WR, Duarte-Rojo A. Hemoglobin A1c has Suboptimal Performance to Diagnose and Monitor Diabetes Mellitus in Patients with Cirrhosis. Dig Dis Sci. 2018 Dec;63(12):3498-3508.

van Tilborg M, Al Marzooqi SH, Wong WWL, Maan R, Vermehren J, Maasoumy B, Mazzulli T, Bolotin S, Garber G, Guerra F, Flud CR, Kowgier M, Janssen HL, de Knegt RJ, Pawlotsky JM, Cloherty GA, Duarte-Rojo A, Sarrazin C, Wedemeyer H, Feld JJ. HCV Core Antigen as an Alternative to HCV RNA Testing in the Era of Direct-acting Antivirals: Retrospective Screening and Diagnostic Cohort Studies. Lancet Gastroenterol Hepatol. 2018 Dec;3(12):856-64.

Bhanji RA, Moctezuma-Velazquez C, Duarte-Rojo A, Ebadi M, Ghosh S, Rose C, Montano-Loza AJ. Myosteatosis and Sarcopenia are Associated with Hepatic Encephalopathy in Patients with Cirrhosis. Hepatol Int. 2018 Jul;12(4):377-86.

George N, Harrell SM, Rhodes KD, Duarte-Rojo A. Recreational Drug and Psychosocial Profile in Chronic Hepatitis C Patients Seeking Antiviral Therapy. Ann Hepatol. 2018 January-February;17(1):76-84.

Thompson J, Jones N, Al-Khafaji A, Malik S, Reich D, Munoz S, MacNicholas R, Hassanein T, Teperman L, Stein L, Duarte-Rojo A, Malik R, Adhami T, Asrani S, Shah N, Gaglio P, Duddempudi A, Borg B, Jalan R, Brown R, Patton H, Satoskar R, Rossi S, Parikh A, ElSharkawy A, Mantry P, Sher L, Wolf D, Hart M, Landis C, Wigg A, Habib S, McCaughan G, Colquhoun S, Henry A, Bedard P, Landeen L, Millis M, Ashley R, Frank W, Henry A, Stange J, Subramanian R; VTI-208 Study Group. Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial. Liver Transpl. 2018 Mar;24(3):380-393.

Maan R, Al Marzooqi SH, Klair JS, Karkada J, Cerocchi O, Kowgier M, Harrell SM, Rhodes KD, Janssen HLA, Feld JJ, Duarte-Rojo A. The frequency of acute kidney injury in patients with chronic hepatitis C virus infection treated with sofosbuvir-based regimens. Aliment Pharmacol Ther. 2017 Jul;46(1):46-55.

Garcia-Saenz-de-Sicilia M, Duvoor C, Altamirano J, Chavez-Araujo R, Prado V, de Lourdes Candolo-Martinelli A, Holanda-Almeida P, Becerra-Martins-de-Oliveira B, Fernandez-de-Almeida S, Bataller R, Caballeria J, Duarte-Rojo A. A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. Am J Gastroenterol. 2017 Feb;112(2):306-315.

Ruiz-Margáin A, Macías-Rodríguez RU, Ampuero J, Cubero FJ, Chi-Cervera L, Ríos-Torres SL, Duarte-Rojo A, Espinosa-Cuevas Á, Romero-Gómez M, Torre A. Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis. World J Gastroenterol. 2016 Dec 7;22(45):10064-10070.

Macías-Rodríguez RU, Ilarraza-Lomelí H, Ruiz-Margáin A, Ponce-de-León-Rosales S, Vargas-Vorácková F, García-Flores O, Torre A, Duarte-Rojo A. Changes in Hepatic Venous Pressure Gradient Induced by Physical Exercise in Cirrhosis: Results of a Pilot Randomized Open Clinical Trial. Clin Transl Gastroenterol. 2016 Jul 14;7(7):e180.

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may not alter the natural history of idiopathic recurrent acute pancreatitis (IRAP). Pancreatology. 2016 Sep-Oct;16(5):770-7.

Brian M. Davis, PhDSnyder LM, Chiang MC, Loeza-Alcocer E, Omori &, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE. Kappa Opioid Receptor Distribution and Function in Primary Afferents. Neuron. 2018 Sep 19;99(6):1274-88.

Saloman JL, Singhi AD, Hartman DJ, Normolle DP, Albers KM, Davis BM. Systemic Depletion of Nerve Grown Factor Inhibits Disease Progression in a Genetically Engineered Model of Pancreatic Ductal Adenocarcinoma. Pancreas. 2018 Aug;47(7):856-63.




Smith-Edwards KM, DeBerry JJ, Saloman JL, Davis BM, Woodbury CJ. Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators. Elife. 2016 Nov 2;5.


Andres Duarte-Rojo, MD, MS, DScSiongal AG, Rich NE, Mehta N, Branch A, Pilai A, Hoteit M, Volk M, Odewole M, Scaglione S, Guy J, Said A, Feld JJ, John BV, Frenette C, Mantry P, Rangnekar AS, Oloruntoba O, Leise M, Jou JH, Bhamidimarri KR, Kulik L, Tran T, Samant H. Dhanasekaran R, Duarte-Rojo A, Salgia R, Eswaran S, Jalal P, Flores A, Satapathy SK, Wong R, Huang A, Misra S, Schwartz M, Mitrani R, Nakka S, Noureddine W, Ho C, Konjeti VR, Dao A, Nelson K, Delarose K, Rahim U, Mavuram M, Xie JJ, Murphy CC, Parikh ND. Direct-acting Antiviral Theraphy Not Associate with Recurrence of Hepatocellular Carcinoma in a Multicenter North American Cohort Study. Gastroenterology. 2019 May;156(6):1683-92.

Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL. Frailty Associated with Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study. Gastroenterolgy. 2019 May;156(6):1675-82.

Smeets XJNM, Knoester I, Grooteman KV, Singh VK, Banks PA, Papachristou GI, Duarte-Rojo A, Robles-Diaz G, Kievit W, Besselink MGH, Verdonk RC, Van Santvoort HC, Drenth JPH, Belias M, Van Geenen EJM, Eutch

Pancreatitis Study Group. The Associate Between Obesity and Outcomes in Acute Pancreatitis: An Individual Patient Data Meta-analysis. Eur J Gastroenterol Hepatol. 2019 Mar;31(3):316-22.

Duarte-Rojo A, Allampati S, Thacker LR, Flud CR, Patidar KR, White MB, Klair JS, Heuman DM, Wade JB, Gavis EA, Bajaj JS. Diagnosis of Covert Hepatic Encephalopahy: A Multi-center Study Testing the Utility of Single Versus Combined Testing. Metab Brain Dis. 2019 Feb;34(1):289-95.

Addepally NS, George N, Martinez-Macias R, Garcia-Saenz-de-Sicilia M, Kim WR, Duarte-Rojo A. Hemoglobin A1c has Suboptimal Performance to Diagnose and Monitor Diabetes Mellitus in Patients with Cirrhosis. Dig Dis Sci. 2018 Dec;63(12):3498-3508.

van Tilborg M, Al Marzooqi SH, Wong WWL, Maan R, Vermehren J, Maasoumy B, Mazzulli T, Bolotin S, Garber G, Guerra F, Flud CR, Kowgier M, Janssen HL, de Knegt RJ, Pawlotsky JM, Cloherty GA, Duarte-Rojo A, Sarrazin C, Wedemeyer H, Feld JJ. HCV Core Antigen as an Alternative to HCV RNA Testing in the Era of Direct-acting Antivirals: Retrospective Screening and Diagnostic Cohort Studies. Lancet Gastroenterol Hepatol. 2018 Dec;3(12):856-64.

Bhanji RA, Moctezuma-Velazquez C, Duarte-Rojo A, Ebadi M, Ghosh S, Rose C, Montano-Loza AJ. Myosteatosis and Sarcopenia are Associated with Hepatic Encephalopathy in Patients with Cirrhosis. Hepatol Int. 2018 Jul;12(4):377-86.

George N, Harrell SM, Rhodes KD, Duarte-Rojo A. Recreational Drug and Psychosocial Profile in Chronic Hepatitis C Patients Seeking Antiviral Therapy. Ann Hepatol. 2018 January-February;17(1):76-84.

Thompson J, Jones N, Al-Khafaji A, Malik S, Reich D, Munoz S, MacNicholas R, Hassanein T, Teperman L, Stein L, Duarte-Rojo A, Malik R, Adhami T, Asrani S, Shah N, Gaglio P, Duddempudi A, Borg B, Jalan R, Brown R, Patton H, Satoskar R, Rossi S, Parikh A, ElSharkawy A, Mantry P, Sher L, Wolf D, Hart M, Landis C, Wigg A, Habib S, McCaughan G, Colquhoun S, Henry A, Bedard P, Landeen L, Millis M, Ashley R, Frank W, Henry A, Stange J, Subramanian R; VTI-208 Study Group. Extracorporeal cellular therapy (ELAD) in severe alcoholic hepatitis: A multinational, prospective, controlled, randomized trial. Liver Transpl. 2018 Mar;24(3):380-393.

Maan R, Al Marzooqi SH, Klair JS, Karkada J, Cerocchi O, Kowgier M, Harrell SM, Rhodes KD, Janssen HLA, Feld JJ, Duarte-Rojo A. The frequency of acute kidney injury in patients with chronic hepatitis C virus infection treated with sofosbuvir-based regimens. Aliment Pharmacol Ther. 2017 Jul;46(1):46-55.

Garcia-Saenz-de-Sicilia M, Duvoor C, Altamirano J, Chavez-Araujo R, Prado V, de Lourdes Candolo-Martinelli A, Holanda-Almeida P, Becerra-Martins-de-Oliveira B, Fernandez-de-Almeida S, Bataller R, Caballeria J, Duarte-Rojo A. A Day-4 Lille Model Predicts Response to Corticosteroids and Mortality in Severe Alcoholic Hepatitis. Am J Gastroenterol. 2017 Feb;112(2):306-315.

Ruiz-Margáin A, Macías-Rodríguez RU, Ampuero J, Cubero FJ, Chi-Cervera L, Ríos-Torres SL, Duarte-Rojo A, Espinosa-Cuevas Á, Romero-Gómez M, Torre A. Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis. World J Gastroenterol. 2016 Dec 7;22(45):10064-10070.

Macías-Rodríguez RU, Ilarraza-Lomelí H, Ruiz-Margáin A, Ponce-de-León-Rosales S, Vargas-Vorácková F, García-Flores O, Torre A, Duarte-Rojo A. Changes in Hepatic Venous Pressure Gradient Induced by Physical Exercise in Cirrhosis: Results of a Pilot Randomized Open Clinical Trial. Clin Transl Gastroenterol. 2016 Jul 14;7(7):e180.

72



Richard H. Duerr, MDRivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS, Beaugerie L, Seksik P, Cosnes J, Schreiber S, Bokemeyer B, Bethge J; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; T2D-GENES Consortium, Heap G, Ahmad T, Plagnol V, Segal AW, Targan S, Turner D, Saavalainen P, Farkkila M, Kontula K, Palotie A, Brant SR, Duerr RH, Silverberg MS, Rioux JD, Weersma RK, Franke A, Jostins L, Anderson CA, Barrett JC, MacArthur DG, Jalas C, Sokol H, Xavier RJ, Pulver A, Cho JH, McGovern DPB, Daly MJ. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. PLoS Genet. 2018 May 24;14(5):e1007329.

Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, Ruane D, Gettler K, Chen E, Li D, Schiff ER, Pontikos N, Barzilai N, Brant SR, Bressman S, Cheifetz AS, Clark LN, Daly MJ, Desnick RJ, Duerr RH, Katz S, Lencz T, Myers RH, Ostrer H, Ozelius L, Payami H, Peter Y, Rioux JD, Segal AW, Scott WK, Silverberg MS, Vance JM, Ubarretxena-Belandia I, Foroud T, Atzmon G, Pe'er I, Ioannou Y, McGovern DPB, Yue Z, Schadt EE, Cho JH, Peter I. Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Sci Transl Med. 2018 Jan 10;10(423).

Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ; WGS500 Consortium; Oxford IBD cohort study investigators; COLORS in IBD group investigators; UK IBD Genetics Consortium, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J; INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunol. 2018 Mar;11(2):562-574.

Parian A, Limketkai B, Koh J, Brant SR, Bitton A, Cho JH, Duerr RH, McGovern DP, Proctor DD, Regueiro MD, Rioux JD, Schumm P, Taylor KD, Silverberg MS, Steinhart AH, Hernaez R, Lazarev M. Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis. Gut. 2017 Aug;66(8):1390-1397.

Huang H, Fang M, Jostins L, Umićević Mirkov M, Boucher G, Anderson CA, Andersen V, Cleynen I, Cortes A, Crins F, D'Amato M, Deffontaine V, Dmitrieva J, Docampo E, Elansary M, Farh KK, Franke A, Gori AS, Goyette P, Halfvarson J, Haritunians T, Knight J, Lawrance IC, Lees CW, Louis E, Mariman R, Meuwissen T, Mni M, Momozawa Y, Parkes M, Spain SL, Théâtre E, Trynka G, Satsangi J, van Sommeren S, Vermeire S, Xavier RJ; International Inflammatory Bowel Disease Genetics Consortium, Weersma RK, Duerr RH, Mathew CG, Rioux JD, McGovern DPB, Cho JH, Georges M, Daly MJ, Barrett JC. Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature. 2017 Jul 13;547(7662):173-178.

Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rosen-Wolff A, Minden K, Tenbrock K, Demirkaya E, Cobb J, Baskin E, Signa S, Shuldiner E, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A; British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, Inception Cohort of Newly Diagnosed Patients with

Juvenile Idiopathic Arthritis (ICON-JIA) Study Group, Childhood Arthritis Prospective Study (CAPS) Group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group, Biologically Based Outcome Predictors in JIA (BBOP) Group, Langefeld CD, Thompson S, Zeggini E, Kastner DL, Woo P, Thomson W. Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications. Ann Rheum Dis. 2017 May;76(5):906-913.

Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 Jan;152(1):206-217.e2.

Kopylov U, Boucher G, Waterman M, Rivers CR, Patel M, Cho JH, Colombel JF, Duerr RH, Binion D, McGovern DP, Schumm PP, Brant SR, Silverberg MS, Rioux JD, Bitton A. Genetic Predictors of Benign Course of Ulcerative Colitis-A North American Inflammatory Bowel Disease Genetics Consortium Study. Inflamm Bowel Dis. 2016 Oct;22(10):2311-6.

Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor DD, Regueiro M, Simms LA, Stempak JM, Targan SR, Törkvist L, Sharma Y, Devlin B, Borneman J, Hakonarson H, Xavier RJ, Daly M, Brant SR, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern DP, Duerr RH. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology. 2016 Oct;151(4):724-32.

Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Evelyn Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, Schiff ER, Gusev A, Schumm LP, Bowen BM, Sharma Y, Ning K, Remark R, Gnjatic S, Legnani P, George J, Sands BE, Stempak JM, Datta LW, Lipka S, Katz S, Cheifetz AS, Barzilai N, Pontikos N, Abraham C, Dubinsky MJ, Targan S, Taylor K, Rotter JI, Scherl EJ, Desnick RJ, Abreu MT, Zhao H, Atzmon G, Pe'er I, Kugathasan S, Hakonarson H, McCauley JL, Lencz T, Darvasi A, Plagnol V, Silverberg MS, Muise AM, Brant SR, Daly MJ, Segal AW, Duerr RH, Merad M, McGovern DP, Peter I, Cho JH. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology. 2016 Oct;151(4):710-723.e2.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G,

73



Richard H. Duerr, MDRivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS, Beaugerie L, Seksik P, Cosnes J, Schreiber S, Bokemeyer B, Bethge J; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; T2D-GENES Consortium, Heap G, Ahmad T, Plagnol V, Segal AW, Targan S, Turner D, Saavalainen P, Farkkila M, Kontula K, Palotie A, Brant SR, Duerr RH, Silverberg MS, Rioux JD, Weersma RK, Franke A, Jostins L, Anderson CA, Barrett JC, MacArthur DG, Jalas C, Sokol H, Xavier RJ, Pulver A, Cho JH, McGovern DPB, Daly MJ. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. PLoS Genet. 2018 May 24;14(5):e1007329.

Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, Chuang LS, Carmi S, Villaverde N, Li X, Rivas M, Levine AP, Bao X, Labrias PR, Haritunians T, Ruane D, Gettler K, Chen E, Li D, Schiff ER, Pontikos N, Barzilai N, Brant SR, Bressman S, Cheifetz AS, Clark LN, Daly MJ, Desnick RJ, Duerr RH, Katz S, Lencz T, Myers RH, Ostrer H, Ozelius L, Payami H, Peter Y, Rioux JD, Segal AW, Scott WK, Silverberg MS, Vance JM, Ubarretxena-Belandia I, Foroud T, Atzmon G, Pe'er I, Ioannou Y, McGovern DPB, Yue Z, Schadt EE, Cho JH, Peter I. Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease. Sci Transl Med. 2018 Jan 10;10(423).

Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ; WGS500 Consortium; Oxford IBD cohort study investigators; COLORS in IBD group investigators; UK IBD Genetics Consortium, Sullivan PB, Rodrigues A, Travis SPL, Moore C, Sambrook J, Ouwehand WH, Roberts DJ, Danesh J; INTERVAL Study, Russell RK, Wilson DC, Kelsen JR, Cornall R, Denson LA, Kugathasan S, Knaus UG, Serra EG, Anderson CA, Duerr RH, McGovern DP, Cho J, Powrie F, Li VS, Muise AM, Uhlig HH. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunol. 2018 Mar;11(2):562-574.

Parian A, Limketkai B, Koh J, Brant SR, Bitton A, Cho JH, Duerr RH, McGovern DP, Proctor DD, Regueiro MD, Rioux JD, Schumm P, Taylor KD, Silverberg MS, Steinhart AH, Hernaez R, Lazarev M. Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis. Gut. 2017 Aug;66(8):1390-1397.

Huang H, Fang M, Jostins L, Umićević Mirkov M, Boucher G, Anderson CA, Andersen V, Cleynen I, Cortes A, Crins F, D'Amato M, Deffontaine V, Dmitrieva J, Docampo E, Elansary M, Farh KK, Franke A, Gori AS, Goyette P, Halfvarson J, Haritunians T, Knight J, Lawrance IC, Lees CW, Louis E, Mariman R, Meuwissen T, Mni M, Momozawa Y, Parkes M, Spain SL, Théâtre E, Trynka G, Satsangi J, van Sommeren S, Vermeire S, Xavier RJ; International Inflammatory Bowel Disease Genetics Consortium, Weersma RK, Duerr RH, Mathew CG, Rioux JD, McGovern DPB, Cho JH, Georges M, Daly MJ, Barrett JC. Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature. 2017 Jul 13;547(7662):173-178.

Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg AM, Wedderburn LR, Anton J, Haas JP, Rosen-Wolff A, Minden K, Tenbrock K, Demirkaya E, Cobb J, Baskin E, Signa S, Shuldiner E, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A; British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, Inception Cohort of Newly Diagnosed Patients with

Juvenile Idiopathic Arthritis (ICON-JIA) Study Group, Childhood Arthritis Prospective Study (CAPS) Group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group, Biologically Based Outcome Predictors in JIA (BBOP) Group, Langefeld CD, Thompson S, Zeggini E, Kastner DL, Woo P, Thomson W. Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications. Ann Rheum Dis. 2017 May;76(5):906-913.

Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, Herrinton LJ, Klapproth JA, Quiros AJ, Seminerio J, Liu Z, Alexander JS, Baldassano RN, Dudley-Brown S, Cross RK, Dassopoulos T, Denson LA, Dhere TA, Dryden GW, Hanson JS, Hou JK, Hussain SZ, Hyams JS, Isaacs KL, Kader H, Kappelman MD, Katz J, Kellermayer R, Kirschner BS, Kuemmerle JF, Kwon JH, Lazarev M, Li E, Mack D, Mannon P, Moulton DE, Newberry RD, Osuntokun BO, Patel AS, Saeed SA, Targan SR, Valentine JF, Wang MH, Zonca M, Rioux JD, Duerr RH, Silverberg MS, Cho JH, Hakonarson H, Zwick ME, McGovern DP, Kugathasan S. Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 Jan;152(1):206-217.e2.

Kopylov U, Boucher G, Waterman M, Rivers CR, Patel M, Cho JH, Colombel JF, Duerr RH, Binion D, McGovern DP, Schumm PP, Brant SR, Silverberg MS, Rioux JD, Bitton A. Genetic Predictors of Benign Course of Ulcerative Colitis-A North American Inflammatory Bowel Disease Genetics Consortium Study. Inflamm Bowel Dis. 2016 Oct;22(10):2311-6.

Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, Aumais G, Baidoo L, Dubinsky M, Fiocchi C, Glas J, Milgrom R, Proctor DD, Regueiro M, Simms LA, Stempak JM, Targan SR, Törkvist L, Sharma Y, Devlin B, Borneman J, Hakonarson H, Xavier RJ, Daly M, Brant SR, Rioux JD, Silverberg MS, Cho JH, Braun J, McGovern DP, Duerr RH. A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. Gastroenterology. 2016 Oct;151(4):724-32.

Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Evelyn Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, Schiff ER, Gusev A, Schumm LP, Bowen BM, Sharma Y, Ning K, Remark R, Gnjatic S, Legnani P, George J, Sands BE, Stempak JM, Datta LW, Lipka S, Katz S, Cheifetz AS, Barzilai N, Pontikos N, Abraham C, Dubinsky MJ, Targan S, Taylor K, Rotter JI, Scherl EJ, Desnick RJ, Abreu MT, Zhao H, Atzmon G, Pe'er I, Kugathasan S, Hakonarson H, McCauley JL, Lencz T, Darvasi A, Plagnol V, Silverberg MS, Muise AM, Brant SR, Daly MJ, Segal AW, Duerr RH, Merad M, McGovern DP, Peter I, Cho JH. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology. 2016 Oct;151(4):710-723.e2.

Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, Vermeire S, Weersma RK, Halfvarson J, Paavola-Sakki P, Lappalainen M, Lek M, Cummings B, Tukiainen T, Haritunians T, Halme L, Koskinen LL, Ananthakrishnan AN, Luo Y, Heap GA, Visschedijk MC; UK IBD Genetics Consortium; NIDDK IBD Genetics Consortium, MacArthur DG, Neale BM, Ahmad T, Anderson CA, Brant SR, Duerr RH, Silverberg MS, Cho JH, Palotie A, Saavalainen P, Kontula K, Färkkilä M, McGovern DP, Franke A, Stefansson K, Rioux JD, Xavier RJ, Daly MJ, Barrett J, de Lane K, Edwards C, Hart A, Hawkey C, Jostins L, Kennedy N, Lamb C, Lee J, Lees C, Mansfield J, Mathew C, Mowatt C, Newman B, Nimmo E, Parkes M, Pollard M, Prescott N, Randall J, Rice D, Satsangi J, Simmons A, Tremelling M, Uhlig H, Wilson D, Abraham C, Achkar JP, Bitton A, Boucher G,

74



Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat Commun. 2016 Aug 9;7:12342.

Mohannad Dugum, , MDKakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-Related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-1363.

Glass D, Huang DT, Dugum M, Chintamaneni P, Cua S, Saul M, Marsh W, Al-Khafaji A. Rectal Trumpet-Associated Hemorrhage in the Intensive Care Unit: A Quality Improvement Initiative. J Wound Ostomy Continence Nurs. 2018 Nov/Dec;45(6):516-520.

Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe SJD, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severity of Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Klinge M, Coppler T, Liebschutz JM, Dugum M, Wassan A, DiMartini A, Rogal S. The assessment and management of pain in cirrhosis. Curr Hepatol Rep. 2018 Mar;17(1):42-51.

Gougol A, Dugum M, Dudekula A, Greer P, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Clinical outcomes of isolated renal failure compared to other forms of organ failure in patients with severe acute pancreatitis. World J Gastroenterol. 2017 Aug 7;23(29):5431-5437.

Papachristou GI, Machicado JD, Stevens T, Goenka MK, Ferreira M, Gutierrez SC, Singh VK, Kamal A, Gonzalez-Gonzalez JA, Pelaez-Luna M, Gulla A, Zarnescu NO, Triantafyllou K, Barbu ST, Easler J, Ocampo C, Capurso G, Archibugi L, Cote GA, Lambiase L, Kochhar R, Chua T, Tiwari SC, Nawaz H, Park WG, de-Madaria E, Lee PJ, Wu BU, Greer PJ, Dugum M, Koutroumpakis E, Akshintala V, Gougol A. Acute pancreatitis patient registry to examine novel therapies in clinical experience (APPRENTICE): an international, multicenter consortium for the study of acute pancreatitis. Ann Gastroenterol. 2017;30(1):106-113.

Dugum M, Lin J, Lopez R, Estfan B, Manilich E, Stocchi L, Shen B, Liu X. Recurrence and survival rates of inflammatory bowel disease-associated colorectal cancer following postoperative chemotherapy: a comparative study. Gastroenterol Rep (Oxf). 2017 Feb;5(1):57-61.

Michael A. Dunn, MDLai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL. Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study. Gastroenterology. 2019 May;156(6):1675-1682.

Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Humar A, Sood P, Rachakonda V, Dunn MA, Tevar AD. Gait Speed and Grip Strength Are Associated With Dropping Out of the Liver Transplant Waiting List. Transplant Proc. 2019 Apr;51(3):794-797.

Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC.

Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ; From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium. Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle. 2018 Dec;9(6):1053-1062.

Chascsa DM, Lai JC, Dunn MA, Montano-Loza AJ, Kappus MR, Dasarathy S, Carey EJ. Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation. Dig Dis Sci. 2018 Dec;63(12):3290-3296.

Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun 8;24(7):1380-1388.




Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG. Peripheral Eosinophilia in Patients With Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype. Am J Gastroenterol. 2017 Dec;112(12):1849-1858.


Kabiri M, Chhatwal J, Donohue JM, Roberts MS, James AE, Dunn MA, Gellad WF. Long-term disease and economic outcomes of prior authorization criteria for Hepatitis C treatment in Pennsylvania Medicaid. Healthc (Amst). 2017 Sep;5(3):105-111.

Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA; Fitness, Life Enhancement, and Exercise in Liver Transplantation Consortium. A multicenter study to define sarcopenia in patients with end-stage liver disease. Liver Transpl. 2017 May;23(5):625-633.

75



Croitoru K, Fleshner P, Glas J, Kugathasan S, Limbergen JV, Milgrom R, Proctor D, Regueiro M, Schumm PL, Sharma Y, Stempak JM, Targan SR, Wang MH. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nat Commun. 2016 Aug 9;7:12342.

Mohannad Dugum, , MDKakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-Related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-1363.

Glass D, Huang DT, Dugum M, Chintamaneni P, Cua S, Saul M, Marsh W, Al-Khafaji A. Rectal Trumpet-Associated Hemorrhage in the Intensive Care Unit: A Quality Improvement Initiative. J Wound Ostomy Continence Nurs. 2018 Nov/Dec;45(6):516-520.


Klinge M, Coppler T, Liebschutz JM, Dugum M, Wassan A, DiMartini A, Rogal S. The assessment and management of pain in cirrhosis. Curr Hepatol Rep. 2018 Mar;17(1):42-51.



Dugum M, Lin J, Lopez R, Estfan B, Manilich E, Stocchi L, Shen B, Liu X. Recurrence and survival rates of inflammatory bowel disease-associated colorectal cancer following postoperative chemotherapy: a comparative study. Gastroenterol Rep (Oxf). 2017 Feb;5(1):57-61.

Michael A. Dunn, MDLai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL. Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study. Gastroenterology. 2019 May;156(6):1675-1682.

Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Humar A, Sood P, Rachakonda V, Dunn MA, Tevar AD. Gait Speed and Grip Strength Are Associated With Dropping Out of the Liver Transplant Waiting List. Transplant Proc. 2019 Apr;51(3):794-797.

Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC.

Sarcopenia Predicts Posttransplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation. Transplantation. 2019 Apr 8. [Epub ahead of print]

Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ; From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium. Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis. J Cachexia Sarcopenia Muscle. 2018 Dec;9(6):1053-1062.

Chascsa DM, Lai JC, Dunn MA, Montano-Loza AJ, Kappus MR, Dasarathy S, Carey EJ. Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation. Dig Dis Sci. 2018 Dec;63(12):3290-3296.

Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Between Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun 8;24(7):1380-1388.




Click B, Anderson AM, Koutroubakis IE, Rivers CR, Babichenko D, Machicado JD, Hartman DJ, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A III, Wenzel SE, Regueiro M, Binion DG. Peripheral Eosinophilia in Patients With Inflammatory Bowel Disease Defines an Aggressive Disease Phenotype. Am J Gastroenterol. 2017 Dec;112(12):1849-1858.


Kabiri M, Chhatwal J, Donohue JM, Roberts MS, James AE, Dunn MA, Gellad WF. Long-term disease and economic outcomes of prior authorization criteria for Hepatitis C treatment in Pennsylvania Medicaid. Healthc (Amst). 2017 Sep;5(3):105-111.

Carey EJ, Lai JC, Wang CW, Dasarathy S, Lobach I, Montano-Loza AJ, Dunn MA; Fitness, Life Enhancement, and Exercise in Liver Transplantation Consortium. A multicenter study to define sarcopenia in patients with end-stage liver disease. Liver Transpl. 2017 May;23(5):625-633.

76




Dunn MA, Josbeno DA, Tevar AD, Rachakonda V, Ganesh SR, Schmotzer AR, Kallenborn EA, Behari J, Landsittel DP, DiMartini AF, Delitto A. Frailty as Tested by Gait Speed is an Independent Risk Factor for Cirrhosis Complications that Require Hospitalization. Am J Gastroenterol. 2016 Dec;111(12):1768-1775.



Sinelnikov A, Qu C, Fetzer DT, Pelletier JS, Dunn MA, Tsung A, Furlan A. Measurement of skeletal muscle area: Comparison of CT and MR imaging. Eur J Radiol. 2016 Oct;85(10):1716-1721.

Dunn MA, Josbeno DA, Schmotzer AR, Tevar AD, DiMartini AF, Landsittel DP, Delitto A. The gap between clinically assessed physical performance and objective physical activity in liver transplant candidates. Liver Transpl. 2016 Oct;22(10):1324-32.


Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schwartz M, Swoger J, Baidoo L, Hashash JG, Barrie A, Dunn MA, Binion DG. Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. J Clin Gastroenterol. 2016 Sep;50(8):638-43.



Kenneth E. Fasanella, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut, 2019 Apr 10. [Epub ahead of print]

Ooka K, Fasanella KE, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer. Gastroenterology. 2019 Mar;156(4):e10-e11.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade Dysplasia Diagnosis Ratio and Progression Metrics Identify Variable Barrett's Esophagus Risk Stratification Proficiency in Independent Pathology Practices. Gastrointest Endosc. 2018 Nov;88(5):807-15.

Chao DT, Shah NH, Zeh NJ erd, Singhi AD, Bahary N, McGrath KM, Fasanella KE, Zureikat AH, Whitcomb DC, Brand RE. Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age. Gastroenterol Res Pract. 2018 June 5;2018:2380596.

Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology. 2018 Mar 2;154(8):2060-2063.e8.

Kurin M, Lee K, Gardner P, Fajt M, Umapathy C, Fasanella K. Clinical Peritonitis from Allergy to Silicone Ventriculoperitoneal Shunt. Clin J Gastroenterol. 2017 Jun;10(3):229-231.

Borhani AA, Fasanella KE, Iranpour N, Zureikat AH, Singhi AD, Furlan A, Dasyam AK. Lymphoepithelial Cyst of Pancreas: Spectrum of Radiological Findings with Pathologic Correlation. Abdom Radiol (NY). 2017 Mar;42(3):877-883.

Alison J. Faust, MD, MHSRogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A. Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS One. 2016 Nov 7;11(11):e0165517.

Rogal S, Mankaney G, Udawatta V, Good CB, Chinman M, Zickmund S, Bielefeldt K, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Humar A, DiMartini A, Fine MJ. Association between opioid use and readmission following liver transplantation. Clin Transplant. 2016 Oct;30(10):1222-1229.

Fadi F. Francis, MD*Francis FF, Frye R, Hashash JG. Cholelithiasis and Biliary Cirrhosis in a 28-Year-Old Man. Clin Gastroenterol Hepatol. 2017 May;15(5):A31-A32.

Swaytha R. Ganesh, MDKhalil A, Ganesh S, Hughes C, Tevar AD, Hasche JJ, Esper S, Humar A. Evaluation of the Enhanced Recovery After Surgery Protocol in Living Liver Donors. Clin Transplant. 2018 Aug;32(8):e13342.

77







Sinelnikov A, Qu C, Fetzer DT, Pelletier JS, Dunn MA, Tsung A, Furlan A. Measurement of skeletal muscle area: Comparison of CT and MR imaging. Eur J Radiol. 2016 Oct;85(10):1716-1721.

Dunn MA, Josbeno DA, Schmotzer AR, Tevar AD, DiMartini AF, Landsittel DP, Delitto A. The gap between clinically assessed physical performance and objective physical activity in liver transplant candidates. Liver Transpl. 2016 Oct;22(10):1324-32.


Koutroubakis IE, Ramos-Rivers C, Regueiro M, Koutroumpakis E, Click B, Schwartz M, Swoger J, Baidoo L, Hashash JG, Barrie A, Dunn MA, Binion DG. Five-Year Period Prevalence and Characteristics of Anemia in a Large US Inflammatory Bowel Disease Cohort. J Clin Gastroenterol. 2016 Sep;50(8):638-43.



Kenneth E. Fasanella, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut, 2019 Apr 10. [Epub ahead of print]

Ooka K, Fasanella KE, Hashash JG. An Unusual Cause of a Solitary Giant Gastric Ulcer. Gastroenterology. 2019 Mar;156(4):e10-e11.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly Accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade Dysplasia Diagnosis Ratio and Progression Metrics Identify Variable Barrett's Esophagus Risk Stratification Proficiency in Independent Pathology Practices. Gastrointest Endosc. 2018 Nov;88(5):807-15.

Chao DT, Shah NH, Zeh NJ erd, Singhi AD, Bahary N, McGrath KM, Fasanella KE, Zureikat AH, Whitcomb DC, Brand RE. Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age. Gastroenterol Res Pract. 2018 June 5;2018:2380596.

Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology. 2018 Mar 2;154(8):2060-2063.e8.

Kurin M, Lee K, Gardner P, Fajt M, Umapathy C, Fasanella K. Clinical Peritonitis from Allergy to Silicone Ventriculoperitoneal Shunt. Clin J Gastroenterol. 2017 Jun;10(3):229-231.

Borhani AA, Fasanella KE, Iranpour N, Zureikat AH, Singhi AD, Furlan A, Dasyam AK. Lymphoepithelial Cyst of Pancreas: Spectrum of Radiological Findings with Pathologic Correlation. Abdom Radiol (NY). 2017 Mar;42(3):877-883.

Alison J. Faust, MD, MHSRogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A. Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS One. 2016 Nov 7;11(11):e0165517.


Fadi F. Francis, MD*Francis FF, Frye R, Hashash JG. Cholelithiasis and Biliary Cirrhosis in a 28-Year-Old Man. Clin Gastroenterol Hepatol. 2017 May;15(5):A31-A32.

Swaytha R. Ganesh, MDKhalil A, Ganesh S, Hughes C, Tevar AD, Hasche JJ, Esper S, Humar A. Evaluation of the Enhanced Recovery After Surgery Protocol in Living Liver Donors. Clin Transplant. 2018 Aug;32(8):e13342.

78



Umapathy C, Seth N, Ganesh S. A Rare Cause of Painful Skin Rash in Crohn's Disease. Gastroenterology. 2017 Jan;152(1):29-30.


Michael S. Gold, PhDJani RH, Hughes MA, Gold MS, Branstetter BF, Ligus ZE, Sekula RJ Jr. Trigeminal Nerve Compression Without Trigeminal Neuralgia: Intraoperative vs. Imaging Evidence. Neurosurgery. 2019 Jan 1;84(1):60-65.

Snyder LM, Chiang MC, Loeza-Alcocer E, Omori Y, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE. Kappa Opioid Receptor Distribution and Function in Primary Afferents. Neuron. 2018 Sep 19;99(6):1274-1288.e6.

Hachisuka J, Omori Y, Chiang MC, Gold MS, Koerber HR, Ross SE. Wind-up in Lamina I Spinoparabrachial Neurons: A Role for Reveberatory Circuits. Pain. 2018 Aug;159(8):1484-93.

Lim G, Farrell LM, Facco FL, Gold MS, Wasan AD. Labor Analgesia as a Predictor for Reduced Postpartum Depression Scores: A Retrospective Observational Study. Anesth Analg. 2018 May;126(5):1598-1605.

Zhang X, Priest BT, Belfer I, Gold MS. Voltage-gated Na+ currents in human dorsal root ganglion neurons. Elife. 2017 May 16;6.

Shiwarski DJ, Tipton A, Giraldo MD, Schmidt BF, Gold MS, Pradhan AA, Puthenveedu MA. A PTEN-Regulated Checkpoint Controls Surface Delivery of δ Opioid Receptors. J Neurosci. 2017 Apr 5;37(14):3741-3752.

Yilmaz E, Watkins SC, Gold MS. Paclitaxel-induced increase in mitochondrial volume mediates dysregulation of intracellular Ca2+ in putative nociceptive glabrous skin neurons from the rat. Cell Calcium. 2017 Mar;62:16-28.

McIlvried LA, Cruz JA, Borghesi LA, Gold MS. Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura. Cephalalgia. 2017 Jan;37(1):36-48.


Liu Q, Gold MS. Opioid-induced Loss of Local Anesthetic Potency in the Rat Sciatic Nerve. Anesthesiology. 2016 Oct;125(4):755-64.

Yilmaz E, Gold MS. Paclitaxel-induced increase in NCX activity in subpopulations of nociceptive afferents: A protective mechanism against chemotherapy-induced peripheral neuropathy? Cell Calcium. 2016 Jul;60(1):25-31.

Julia B. Greer, MD, MPHGreer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD,

Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract. 2019 Jun;34(3):387-399.


Proksell SS, Greer JB, Theisen BK, Davis PL, Rosh JR, Keljo DJ, Goyal A, Shah SA, Brand MH, Herfarth HH, Cross RK, Siegel CA, Koltun WA, Isaacs KL, Regueiro MD. IBD LIVE Case Series: Case 9: Do Race and Extraintestinal Manifestations Affect Treatment of Severe Crohn's Colitis? Inflamm Bowel Dis. 2018 Mar 19;24(4):698-713.


Mehrotra A, Morris M, Gourevitch RA, Carrell DS, Leffler DA, Rose S, Greer JB, Crockett SD, Baer A, Schoen RE. Physician characteristics associated with higher adenoma detection rate. Gastrointest Endosc. 2018 Mar;87(3):778-786.e5.



Koutroumpakis E, Slivka A, Furlan A, Dasyam AK, Dudekula A, Greer JB, Whitcomb DC, Yadav D, Papachristou GI. Management and outcomes of acute pancreatitis patients over the last decade: A US tertiary-center experience. Pancreatology. 2017 Jan - Feb;17(1):32-40.

Rajan D, Greer JB, Regueiro MD, Baidoo L, Binion DG, Herfarth HH, Siegel CA, Hartman DJ, Farraye FA, Koutroubakis IE, Brand MH, Williams ED, Goyal A, Cross RK. IBD LIVE Case Series-Case 6. Inflamm Bowel Dis. 2016 Nov;22(11):2754-2764.


Janet R. Harrison, MDGajendran M, Bauer AJ, Buchholz BM, Watson AR, Koutroubakis IE, Hashash JG, Ramos-Rivers C, Shah N, Lee KK, Cruz RJ, Regueiro M, Zuckerbraun B, Schwartz M, Swoger J, Barrie A, Harrison J, Hartman DJ, Salgado J, Rivers WM, Click B, Anderson AM, Umapathy C, Babichenko D, Dunn MA, Binion DG, Ileocecal Anastomosis Type Significantly Influences Long-Term Functional Status, Quality of Life, and Healthcare Utilization in Postoperative Crohn's Disease Patients Independent of Inflammation Recurrence, Am J

79



Umapathy C, Seth N, Ganesh S. A Rare Cause of Painful Skin Rash in Crohn's Disease. Gastroenterology. 2017 Jan;152(1):29-30.


Michael S. Gold, PhDJani RH, Hughes MA, Gold MS, Branstetter BF, Ligus ZE, Sekula RJ Jr. Trigeminal Nerve Compression Without Trigeminal Neuralgia: Intraoperative vs. Imaging Evidence. Neurosurgery. 2019 Jan 1;84(1):60-65.

Snyder LM, Chiang MC, Loeza-Alcocer E, Omori Y, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE. Kappa Opioid Receptor Distribution and Function in Primary Afferents. Neuron. 2018 Sep 19;99(6):1274-1288.e6.

Hachisuka J, Omori Y, Chiang MC, Gold MS, Koerber HR, Ross SE. Wind-up in Lamina I Spinoparabrachial Neurons: A Role for Reveberatory Circuits. Pain. 2018 Aug;159(8):1484-93.

Lim G, Farrell LM, Facco FL, Gold MS, Wasan AD. Labor Analgesia as a Predictor for Reduced Postpartum Depression Scores: A Retrospective Observational Study. Anesth Analg. 2018 May;126(5):1598-1605.

Zhang X, Priest BT, Belfer I, Gold MS. Voltage-gated Na+ currents in human dorsal root ganglion neurons. Elife. 2017 May 16;6.

Shiwarski DJ, Tipton A, Giraldo MD, Schmidt BF, Gold MS, Pradhan AA, Puthenveedu MA. A PTEN-Regulated Checkpoint Controls Surface Delivery of δ Opioid Receptors. J Neurosci. 2017 Apr 5;37(14):3741-3752.

Yilmaz E, Watkins SC, Gold MS. Paclitaxel-induced increase in mitochondrial volume mediates dysregulation of intracellular Ca2+ in putative nociceptive glabrous skin neurons from the rat. Cell Calcium. 2017 Mar;62:16-28.

McIlvried LA, Cruz JA, Borghesi LA, Gold MS. Sex-, stress-, and sympathetic post-ganglionic-dependent changes in identity and proportions of immune cells in the dura. Cephalalgia. 2017 Jan;37(1):36-48.


Liu Q, Gold MS. Opioid-induced Loss of Local Anesthetic Potency in the Rat Sciatic Nerve. Anesthesiology. 2016 Oct;125(4):755-64.

Yilmaz E, Gold MS. Paclitaxel-induced increase in NCX activity in subpopulations of nociceptive afferents: A protective mechanism against chemotherapy-induced peripheral neuropathy? Cell Calcium. 2016 Jul;60(1):25-31.

Julia B. Greer, MD, MPHGreer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD,

Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract. 2019 Jun;34(3):387-399.




Mehrotra A, Morris M, Gourevitch RA, Carrell DS, Leffler DA, Rose S, Greer JB, Crockett SD, Baer A, Schoen RE. Physician characteristics associated with higher adenoma detection rate. Gastrointest Endosc. 2018 Mar;87(3):778-786.e5.




Rajan D, Greer JB, Regueiro MD, Baidoo L, Binion DG, Herfarth HH, Siegel CA, Hartman DJ, Farraye FA, Koutroubakis IE, Brand MH, Williams ED, Goyal A, Cross RK. IBD LIVE Case Series-Case 6. Inflamm Bowel Dis. 2016 Nov;22(11):2754-2764.


Janet R. Harrison, MDGajendran M, Bauer AJ, Buchholz BM, Watson AR, Koutroubakis IE, Hashash JG, Ramos-Rivers C, Shah N, Lee KK, Cruz RJ, Regueiro M, Zuckerbraun B, Schwartz M, Swoger J, Barrie A, Harrison J, Hartman DJ, Salgado J, Rivers WM, Click B, Anderson AM, Umapathy C, Babichenko D, Dunn MA, Binion DG, Ileocecal Anastomosis Type Significantly Influences Long-Term Functional Status, Quality of Life, and Healthcare Utilization in Postoperative Crohn's Disease Patients Independent of Inflammation Recurrence, Am J

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Gastroenterol, 2018 Apr;113(4):576-583.

Chiu WK, Brand RM, Camp D, Edick S, Mitchell C, Karas S, Zehmisch A, Ho K, Brand RE, Harrison J, Abo S, Cranston RD, McGowan I, The Safety of Multiple Flexible Sigmoidoscopies with Mucosal Biopsies in Healthy Clinical Trial Participants, AIDS Res Hum Retrov, 2017 Aug;33(8):820-826.

Elyse Johnston, MDJohnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopist's Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Yadlapati R, Johnston ER, Gluskin AB, Gregory DL, Cyrus R, Werth L, Ciolino JD, Grande DP, Keswani RN. An Automated Inpatient Split-dose Bowel Preparation System Improves Colonscopy Quality and Reduces Repeat Procedures. J Clin Gastroenterol. 2018 Sep;52(8):709-14.

Naudia L. Jonassaint, MD, MHSMolinari M, Sood P, Samra PB, Tevar A, Ganoza A, Jonassaint N, Puttarajappa C. Atrial Fibrillation in Renal or Liver Transplant Recipients: A Systematic Review and Meta-analysis, Transplant Rev. 2019 Jan;33(1):29-38.

Rogal SS, McCarthy R, Reid A, Rodriguez KL, Calgaro L, Patel K, Daley M, Jonassaint NL, Zickmund SL. Primary Care and Hepatology Provider-Perceived Barriers to and Facilitators of Hepatitis C Treatment Candidacy and Adherence. Dig Dis Sci. 2017 Aug;62(8):1933-1943.

Rogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A. Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS One. 2016 Nov 7;11(11):e0165517.

Rogal S, Mankaney G, Udawatta V, Good CB, Chinman M, Zickmund S, Bielefeldt K, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Humar A, DiMartini A, Fine MJ. Association Between Opioid Use and Readmission Following Liver Transplantation. Clin Transplant. 2016 Oct;30(10):1222-1229.

Asif Khalid, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH,

Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam A, Brand R, Fasanella, KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10. [Epub ahead of print]

Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopist's Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly

accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Zator Z, Klinge M, Schraut W, Tsung A, Khalid A. One Step Endoscopic Ultrasound Guided Managemetn of Pelvic Abscesses: A Case Series. Therap Adv Gastroenterol. 2018 Jun 28;11:1756284818785574.

Razzak A, Smith D, Zahid M, Papachristou G, Khalid A. Effect of Quality Metric Monitoring and Colonoscopy Performance. Endosc Int Open. 2016 Oct;4(10):E1023-E1027.

Michael Kingsley, MDJohnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopists' Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

David J. Levinthal, MD, PhDSharaf RN, Venkatesan T, Shah R, Levinthal DJ, Tarbell SE, Jaradeh SS, Hasler WL, Issenman RM, Adams KA, Sarosiek I, Stave CD, Li BUK, Sultan S. Management of Cyclic Vomiting Syndrome in Adults: Evidence Review. Neurogastroenterol Motil. 2019 Jun;31 Suppl 2:e13605.

Vasamsetti SB, Florentin J, Coppin E, Stiekema LCA, Zheng KH, Nisar MU, Sembrat J, Levinthal DJ, Rojas M, Stroes ESG, Kim K, Dutta P. Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation. Immunity. 2018 Jul 17;49(1):93-106.

Kurin M, Bielefeldt K, Levinthal DJ. Prevalence of Nausea and Vomiting in Adults Using Ropinirole: A Systematic Review and Meta-Analysis. Dig Dis Sci. 2018 Mar;63(3):687-693.

Dum RP, Levinthal DJ, Strick PL. Motor, Cognitive, and Affective Areas of the Cerebral Cortex Influence the Adrenal Medulla. Proc Natl Acad Sci USA. 2017 May2;114(18):E3659-E3668.

Yang Liu, PhDMa H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019 Apr 26;5(4):eaaw0683.

Xu J, Liu Y. Imaging Higher-order Chromatin Structures in Single Cells Using Stochastic Optical Reconstruction Microscopy. Bio Protoc. 2019 Feb 5;9(3).

Nmezi B, Xu J, Fu R, Armiger TJ, Rodriguez-Bey G, Powell JS, Ma H, Sullivan M, Tu Y, Chen NY, Young SG, Stolz DB, Dahl KN, Liu Y, Padiath QS. Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina. Proc Natl Acad Sci U S A. 2019 Feb 14.

Teng Y, Yadav T, Duan M, Tan J, Xiang Y, Gao B, Xu J, Liang Z, Liu Y, Nakajima S, Shi Y, Levine AS, Zou L, Lan L. ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB. Nat Commun. 2018 Oct 8;9(1):4115.

Xu J, Ma H, Jin J, Uttam S, Fu R, Huang Y, Liu Y. Super-Resolution Imaging of Higher-Order Chromatin Structures at Different Epigenomic States in Single Mammalian Cells. Cell Rep. 2018 Jul 24;24(4):873-882.

Gao Y, Tan J, Jin J, Ma H, Chen X, Leger B, Xu J, Spagnol ST, Dahl KN, Levine AS, Liu Y, Lan L. SIRT6 facilitates directional telomere movement upon oxidative damage. Sci Rep. 2018 Mar 29;8(1):5407.

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Gastroenterol, 2018 Apr;113(4):576-583.

Chiu WK, Brand RM, Camp D, Edick S, Mitchell C, Karas S, Zehmisch A, Ho K, Brand RE, Harrison J, Abo S, Cranston RD, McGowan I, The Safety of Multiple Flexible Sigmoidoscopies with Mucosal Biopsies in Healthy Clinical Trial Participants, AIDS Res Hum Retrov, 2017 Aug;33(8):820-826.

Elyse Johnston, MDJohnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopist's Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Yadlapati R, Johnston ER, Gluskin AB, Gregory DL, Cyrus R, Werth L, Ciolino JD, Grande DP, Keswani RN. An Automated Inpatient Split-dose Bowel Preparation System Improves Colonscopy Quality and Reduces Repeat Procedures. J Clin Gastroenterol. 2018 Sep;52(8):709-14.

Naudia L. Jonassaint, MD, MHSMolinari M, Sood P, Samra PB, Tevar A, Ganoza A, Jonassaint N, Puttarajappa C. Atrial Fibrillation in Renal or Liver Transplant Recipients: A Systematic Review and Meta-analysis, Transplant Rev. 2019 Jan;33(1):29-38.



Rogal S, Mankaney G, Udawatta V, Good CB, Chinman M, Zickmund S, Bielefeldt K, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Humar A, DiMartini A, Fine MJ. Association Between Opioid Use and Readmission Following Liver Transplantation. Clin Transplant. 2016 Oct;30(10):1222-1229.

Asif Khalid, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH,

Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam A, Brand R, Fasanella, KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10. [Epub ahead of print]

Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopist's Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

Singhi AD, McGrath K, Brand RE, Khalid A, Zeh HJ, Chennat JS, Fasanella KE, Papachristou GI, Slivka A, Bartlett DL, Dasyam AK, Hogg M, Lee KK, Marsh JW, Monaco SE, Ohori NP, Pingpank JF, Tsung A, Zureikat AH, Wald AI, Nikiforova MN. Preoperative Next-generation Sequencing of Pancreatic Cyst Fluid is Highly

accurate in Cyst Classification and Detection of Advanced Neoplasia. Gut. 2018 Dec;67(12):2131-41.

Zator Z, Klinge M, Schraut W, Tsung A, Khalid A. One Step Endoscopic Ultrasound Guided Managemetn of Pelvic Abscesses: A Case Series. Therap Adv Gastroenterol. 2018 Jun 28;11:1756284818785574.

Razzak A, Smith D, Zahid M, Papachristou G, Khalid A. Effect of Quality Metric Monitoring and Colonoscopy Performance. Endosc Int Open. 2016 Oct;4(10):E1023-E1027.

Michael Kingsley, MDJohnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of Bacterial Exposure to the Endoscopists' Face During Endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-24.

David J. Levinthal, MD, PhDSharaf RN, Venkatesan T, Shah R, Levinthal DJ, Tarbell SE, Jaradeh SS, Hasler WL, Issenman RM, Adams KA, Sarosiek I, Stave CD, Li BUK, Sultan S. Management of Cyclic Vomiting Syndrome in Adults: Evidence Review. Neurogastroenterol Motil. 2019 Jun;31 Suppl 2:e13605.

Vasamsetti SB, Florentin J, Coppin E, Stiekema LCA, Zheng KH, Nisar MU, Sembrat J, Levinthal DJ, Rojas M, Stroes ESG, Kim K, Dutta P. Sympathetic Neuronal Activation Triggers Myeloid Progenitor Proliferation and Differentiation. Immunity. 2018 Jul 17;49(1):93-106.

Kurin M, Bielefeldt K, Levinthal DJ. Prevalence of Nausea and Vomiting in Adults Using Ropinirole: A Systematic Review and Meta-Analysis. Dig Dis Sci. 2018 Mar;63(3):687-693.

Dum RP, Levinthal DJ, Strick PL. Motor, Cognitive, and Affective Areas of the Cerebral Cortex Influence the Adrenal Medulla. Proc Natl Acad Sci USA. 2017 May2;114(18):E3659-E3668.

Yang Liu, PhDMa H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019 Apr 26;5(4):eaaw0683.

Xu J, Liu Y. Imaging Higher-order Chromatin Structures in Single Cells Using Stochastic Optical Reconstruction Microscopy. Bio Protoc. 2019 Feb 5;9(3).


Teng Y, Yadav T, Duan M, Tan J, Xiang Y, Gao B, Xu J, Liang Z, Liu Y, Nakajima S, Shi Y, Levine AS, Zou L, Lan L. ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB. Nat Commun. 2018 Oct 8;9(1):4115.



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Xu J, Ma H, Liu Y. Stochastic Optical Reconstruction Microscopy (STORM). Curr Protoc Cytom. 2017 Jul 5;81:12.46.1-12.46.27.

Ma H, Xu J, Jin J, Huang Y, Liu Y. A Simple Marker-Assisted 3D Nanometer Drift Correction Method for Superresolution Microscopy. Biophys J. 2017 May 23;112(10):2196-2208.

Ma H, Fu R, Xu J, Liu Y. A simple and cost-effective setup for super-resolution localization microscopy. Sci Rep. 2017 May 8;7(1):1542.

Gao Y, Li C, Wei L, Teng Y, Nakajima S, Chen X, Xu J, Leger B, Ma H, Spagnol ST, Wan Y, Dahl KN, Liu Y, Levine AS, Lan L. SSRP1 Cooperates with PARP and XRCC1 to Facilitate Single-Strand DNA Break Repair by Chromatin Priming. Cancer Res. 2017 May 15;77(10):2674-2685.

Hongqiang Ma, PhDMa H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019 Apr 26;5(4):eaaw0683.








Shahid M. Malik, MDKakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-63.

Thompson J, Jones N, Al-Khafaji A, Malik S, Reich D, Munoz S, MacNicholas R, Hassanein T, Teperman L, Stein L, Duarte-Rojo A, Malik R, Adhami T, Asrani S, Shah N, Gaglio P, Duddempudi A, Borg B, Jalan R, Brown R, Patton H, Satoskar R, Rossi S, Parikh A, ElSharkawy A, Mantry P, Sher L, Wolf D, Hart M, Landis C, Wigg A, Habib S, McCaughan G, Colquhoun S, Henry A, Bedard P, Landeen L, Millis M, Ashley R, Frank W, Henry A, Stange J, Subramanian R; VTI-208 Study Group. Extracorporeal Cellular Therapy (ELAD) in Severe

Alcoholic Hepatitis: A Multinational, Prospective, Controlled, Randomized Trial. Liver Transpl. 2018 Mar;24(3):380-393.

Tublin ME, Blair R, Martin J, Malik S, Ruppert K, Demetris A. Prospective Study of the Impact of Liver Biopsy Core Size on Specimen Adequacy and Procedural Complications. AJR Am J Roentgenol. 2018 Jan;210(1):183-188.

Kakar S, Borhani AA, Malik SM. A Liver Full of Stars: Hepatostellular! Gastroenterology. 2017 Dec;153(6):e8-e9.

Patel PH, Bibee K, Lim G, Malik SM, Wu C, Pugliano-Mauro M. Evaluating Retention of Skin Cancer Education in Kidney Transplant Recipients Reveals a Window of Opportunity for Re-education. Transplant Proc. 2017 Jul - Aug;49(6):1318-1324.

Chintamaneni P, Stevenson HL, Malik SM. Bupivacaine Drug-Induced Liver Injury: A Case Series and Brief Review of the Literature. J Clin Anesth. 2016 Aug;32:137-41.

Klinge MJ, Borhani AA, Malik SM. Hepatitis C and Numerous Disappearing Hepatic Nodules: No-dule C It, No-dule Don't. Gastroenterology. 2016 Jul;151(1):37-9.

Kevin McGrath, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10. [Epub ahead of print]


Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade dysplasia diagnosis ratio and progression metrics identify variable Barrett's esophagus risk stratification proficiency in independent pathology practices. Gastrointest Endosc. 2018 Nov;88(5):807-815.e2.

McGovern JM, Singhi AD, Borhani AA, Furlan A, McGrath KM, Zeh HJ 3rd, Bahary N, Dasyam AK. CT Radiogenomic Characterization of the Alternative Lengthening of Telomeres Phenotype in Pancreatic Neuroendocrine Tumors. AJR Am J Roentgenol. 2018 Nov;211(5):1020-1025.


Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology.

83







Hongqiang Ma, PhDMa H, Xu J, Liu Y. WindSTORM: Robust online image processing for high-throughput nanoscopy. Sci Adv. 2019 Apr 26;5(4):eaaw0683.








Shahid M. Malik, MDKakar S, Dugum M, Cabello R, Humar A, Ahmad J, Malik SM. Incidence of Recurrent NASH-related Allograft Cirrhosis. Dig Dis Sci. 2019 May;64(5):1356-63.

Thompson J, Jones N, Al-Khafaji A, Malik S, Reich D, Munoz S, MacNicholas R, Hassanein T, Teperman L, Stein L, Duarte-Rojo A, Malik R, Adhami T, Asrani S, Shah N, Gaglio P, Duddempudi A, Borg B, Jalan R, Brown R, Patton H, Satoskar R, Rossi S, Parikh A, ElSharkawy A, Mantry P, Sher L, Wolf D, Hart M, Landis C, Wigg A, Habib S, McCaughan G, Colquhoun S, Henry A, Bedard P, Landeen L, Millis M, Ashley R, Frank W, Henry A, Stange J, Subramanian R; VTI-208 Study Group. Extracorporeal Cellular Therapy (ELAD) in Severe

Alcoholic Hepatitis: A Multinational, Prospective, Controlled, Randomized Trial. Liver Transpl. 2018 Mar;24(3):380-393.

Tublin ME, Blair R, Martin J, Malik S, Ruppert K, Demetris A. Prospective Study of the Impact of Liver Biopsy Core Size on Specimen Adequacy and Procedural Complications. AJR Am J Roentgenol. 2018 Jan;210(1):183-188.

Kakar S, Borhani AA, Malik SM. A Liver Full of Stars: Hepatostellular! Gastroenterology. 2017 Dec;153(6):e8-e9.

Patel PH, Bibee K, Lim G, Malik SM, Wu C, Pugliano-Mauro M. Evaluating Retention of Skin Cancer Education in Kidney Transplant Recipients Reveals a Window of Opportunity for Re-education. Transplant Proc. 2017 Jul - Aug;49(6):1318-1324.

Chintamaneni P, Stevenson HL, Malik SM. Bupivacaine Drug-Induced Liver Injury: A Case Series and Brief Review of the Literature. J Clin Anesth. 2016 Aug;32:137-41.

Klinge MJ, Borhani AA, Malik SM. Hepatitis C and Numerous Disappearing Hepatic Nodules: No-dule C It, No-dule Don't. Gastroenterology. 2016 Jul;151(1):37-9.

Kevin McGrath, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10. [Epub ahead of print]


Davison JM, Shah MB, Deitrick C, Chennat J, Fasanella KE, McGrath K. Low-grade dysplasia diagnosis ratio and progression metrics identify variable Barrett's esophagus risk stratification proficiency in independent pathology practices. Gastrointest Endosc. 2018 Nov;88(5):807-815.e2.

McGovern JM, Singhi AD, Borhani AA, Furlan A, McGrath KM, Zeh HJ 3rd, Bahary N, Dasyam AK. CT Radiogenomic Characterization of the Alternative Lengthening of Telomeres Phenotype in Pancreatic Neuroendocrine Tumors. AJR Am J Roentgenol. 2018 Nov;211(5):1020-1025.


Roy S, LaFramboise WA, Liu TC, Cao D, Luvison A, Miller C, Lyons MA, O'Sullivan RJ, Zureikat AH, Hogg ME, Tsung A, Lee KK, Bahary N, Brand RE, Chennat JS, Fasanella KE, McGrath K, Nikiforova MN, Papachristou GI, Slivka A, Zeh HJ, Singhi AD. Loss of Chromatin-Remodeling Proteins and/or CDKN2A Associates With Metastasis of Pancreatic Neuroendocrine Tumors and Reduced Patient Survival Times. Gastroenterology.

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Singhi AD, Arnold CA, Lam-Himlin DM, Nikiforova MN, Voltaggio L, Canto MI, McGrath KM, Montgomery EA. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod Pathol. 2017 Nov;30(11):1613-1621.

Hamad A, Singhi AD, Bahary N, McGrath K, Amarin R, Zeh HJ, Zureikat AH. Neoadjuvant Treatment With Trastuzumab and FOLFOX Induces a Complete Pathologic Response in a Metastatic ERBB2 (HER2)-Amplified Duodenal Cancer. J Natl Compr Canc Netw. 2017 Aug;15(8):983-988.


Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JV; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. Lancet Respir Med. 2016 Jul;4(7):574-584.

Satdarshan (Paul) Singh Monga, MDMin Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP. β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis. Am J Pathol. 2019 May;189(5):1091-1104.

Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X. TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. Am J Pathol. 2019 May;189(5):1077-1090.

Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP. Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. Cell Metab. 2019 May 7;29(5):1135-1150.e6.

Jiang A, Okabe H, Popovic B, Preziosi ME, Pradhan-Sundd T, Poddar M, Singh S, Bell A, England SG, Nagarajan S, Monga SP. Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet. Am J Pathol. 2019 Mar;189(3):590-603.

Russell JO, Ko S, Monga SP, Shin D. Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish. Stem Cells Int. 2019 Mar 12;2019:8451282.

Molina L, Yang H, Adebayo Michael AO, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SPS. mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development. Oncotarget. 2019 Feb 19;10(15):1475-1490.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang

B, Monga SP, Chen X. Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice. Hepatology. 2019 Feb 8.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K. Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury. J Hepatol. 2019 Jan;70(1):108-117

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D. Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8. Gastroenterology. 2019 Jan;156(1):187-202.e14.

Zhang R, Kikuchi AT, Nakao T, Russell JO, Preziosi ME, Poddar M, Singh S, Bell AW, England SG, Monga SP. Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury. Gene Expr. 2019 Apr 18;19(2):121-136.

Russell JO, Lu WY, Okabe H, Abrams M, Oertel M, Poddar M, Singh S, Forbes SJ, Monga SP. Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes. Hepatology. 2019 Feb;69(2):742-759.

Mattu S, Saliba C, Sulas P, Zavattari P, Perra A, Kowalik MA, Monga SP, Columbano A. High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. Am J Pathol. 2018 Nov;188(11):2497-2507.

Qiao Y, Xu M, Tao J, Che L, Cigliano A, Monga SP, Calvisi DF, Chen X. Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice. BMC Cancer. 2018 Nov 12;18(1):1093.

Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P. Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology. 2018 Oct;155(4):1218-1232.e24.

Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol. 2018 Aug;188(8):1895-1909.

Preziosi M, Poddar M, Singh S, Monga SP. Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer. Gene Expr. 2018 Aug 22;18(3):209-219.

Preziosi M, Okabe H, Poddar M, Singh S, Monga SP. Endothelial Wnts regulate β-catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt-Wnt situation. Hepatol Commun. 2018 Jun 21;2(7):845-860.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP. Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis. Hepatology. 2018 Jun;67(6):2320-2337.

Jamwal G, Singh G, Dar MS, Singh P, Bano N, Syed SH, Sandhu P, Akhter Y, Monga SP, Dar MJ. Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways. Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):920-931.

Russell JO, Ko S, Saggi HS, Singh S, Poddar M, Shin D, Monga SP. Bromodomain and Extraterminal (BET) 85



2018 Jun;154(8):2060-2063.e8.

Singhi AD, Arnold CA, Lam-Himlin DM, Nikiforova MN, Voltaggio L, Canto MI, McGrath KM, Montgomery EA. Targeted next-generation sequencing supports epidermoid metaplasia of the esophagus as a precursor to esophageal squamous neoplasia. Mod Pathol. 2017 Nov;30(11):1613-1621.

Hamad A, Singhi AD, Bahary N, McGrath K, Amarin R, Zeh HJ, Zureikat AH. Neoadjuvant Treatment With Trastuzumab and FOLFOX Induces a Complete Pathologic Response in a Metastatic ERBB2 (HER2)-Amplified Duodenal Cancer. J Natl Compr Canc Netw. 2017 Aug;15(8):983-988.


Peters MC, McGrath KW, Hawkins GA, Hastie AT, Levy BD, Israel E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Holguin F, Wenzel SE, Woodruff PG, Bleecker ER, Fahy JV; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts. Lancet Respir Med. 2016 Jul;4(7):574-584.

Satdarshan (Paul) Singh Monga, MDMin Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP. β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis. Am J Pathol. 2019 May;189(5):1091-1104.

Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X. TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma. Am J Pathol. 2019 May;189(5):1077-1090.

Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP. Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations. Cell Metab. 2019 May 7;29(5):1135-1150.e6.

Jiang A, Okabe H, Popovic B, Preziosi ME, Pradhan-Sundd T, Poddar M, Singh S, Bell A, England SG, Nagarajan S, Monga SP. Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet. Am J Pathol. 2019 Mar;189(3):590-603.

Russell JO, Ko S, Monga SP, Shin D. Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish. Stem Cells Int. 2019 Mar 12;2019:8451282.

Molina L, Yang H, Adebayo Michael AO, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SPS. mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development. Oncotarget. 2019 Feb 19;10(15):1475-1490.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang

B, Monga SP, Chen X. Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice. Hepatology. 2019 Feb 8.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K. Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury. J Hepatol. 2019 Jan;70(1):108-117

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D. Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8. Gastroenterology. 2019 Jan;156(1):187-202.e14.

Zhang R, Kikuchi AT, Nakao T, Russell JO, Preziosi ME, Poddar M, Singh S, Bell AW, England SG, Monga SP. Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury. Gene Expr. 2019 Apr 18;19(2):121-136.

Russell JO, Lu WY, Okabe H, Abrams M, Oertel M, Poddar M, Singh S, Forbes SJ, Monga SP. Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes. Hepatology. 2019 Feb;69(2):742-759.

Mattu S, Saliba C, Sulas P, Zavattari P, Perra A, Kowalik MA, Monga SP, Columbano A. High Frequency of β-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. Am J Pathol. 2018 Nov;188(11):2497-2507.

Qiao Y, Xu M, Tao J, Che L, Cigliano A, Monga SP, Calvisi DF, Chen X. Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice. BMC Cancer. 2018 Nov 12;18(1):1093.

Pradhan-Sundd T, Vats R, Russell JO, Singh S, Michael AA, Molina L, Kakar S, Cornuet P, Poddar M, Watkins SC, Nejak-Bowen KN, Monga SP, Sundd P. Dysregulated Bile Transporters and Impaired Tight Junctions During Chronic Liver Injury in Mice. Gastroenterology. 2018 Oct;155(4):1218-1232.e24.

Molina L, Bell D, Tao J, Preziosi M, Pradhan-Sundd T, Singh S, Poddar M, Luo J, Ranganathan S, Chikina M, Monga SP. Hepatocyte-Derived Lipocalin 2 Is a Potential Serum Biomarker Reflecting Tumor Burden in Hepatoblastoma. Am J Pathol. 2018 Aug;188(8):1895-1909.

Preziosi M, Poddar M, Singh S, Monga SP. Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer. Gene Expr. 2018 Aug 22;18(3):209-219.

Preziosi M, Okabe H, Poddar M, Singh S, Monga SP. Endothelial Wnts regulate β-catenin signaling in murine liver zonation and regeneration: A sequel to the Wnt-Wnt situation. Hepatol Commun. 2018 Jun 21;2(7):845-860.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP. Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis. Hepatology. 2018 Jun;67(6):2320-2337.

Jamwal G, Singh G, Dar MS, Singh P, Bano N, Syed SH, Sandhu P, Akhter Y, Monga SP, Dar MJ. Identification of a unique loss-of-function mutation in IGF1R and a crosstalk between IGF1R and Wnt/β-catenin signaling pathways. Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):920-931.

Russell JO, Ko S, Saggi HS, Singh S, Poddar M, Shin D, Monga SP. Bromodomain and Extraterminal (BET) 86



Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol. 2018 Jun;188(6):1389-1405.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP. The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model. Gene Expr. 2018 May 18;18(2):135-147.

Thompson MD, Moghe A, Cornuet P, Marino R, Tian J, Wang P, Ma X, Abrams M, Locker J, Monga SP, Nejak-Bowen K. β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis. Hepatology. 2018 Mar;67(3):955-971.

Liu C, Ren YF, Dong J, Ke MY, Ma F, Monga SPS, Wu R, Lv Y, Zhang XF. Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma. Cancer Lett. 2017 Dec 1;410:20-31.

Puliga E, Min Q, Tao J, Zhang R, Pradhan-Sundd T, Poddar M, Singh S, Columbano A, Yu J, Monga SP. Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer. Am J Pathol. 2017 Nov;187(11):2473-2485.

Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP. Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. Exp Biol Med (Maywood). 2017 Oct;242(16):1605-1616.

Kikuchi A, Pradhan-Sundd T, Singh S, Nagarajan S, Loizos N, Monga SP. Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration. Am J Pathol. 2017 Oct;187(10):2273-2287.

Chen ZH, Yu YP, Tao J, Liu S, Tseng G, Nalesnik M, Hamilton R, Bhargava R, Nelson JB, Pennathur A, Monga SP, Luketich JD, Michalopoulos GK, Luo JH. MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice. Gastroenterology. 2017 Oct;153(4):1120-1132.e15.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload. J Hepatol. 2017 Aug;67(2):360-369.

Chen ZH, Yu YP, Zuo ZH, Nelson JB, Michalopoulos GK, Monga S, Liu S, Tseng G, Luo JH. Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene. Nat Biotechnol. 2017 Jun;35(6):543-550.

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP. Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice. Hepatology. 2017 May;65(5):1581-1599.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. J Biol Chem. 2016 Dec 16;291(51):26241-26251.

Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN. Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice. Hepatology. 2016 Nov;64(5):1652-1666.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP. Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin. Hepatology. 2016 Nov;64(5):1587-1605.

Ganesh S, Koser ML, Cyr WA, Chopda GR, Tao J, Shui X, Ying B, Chen D, Pandya P, Chipumuro E, Siddiquee Z, Craig K, Lai C, Dudek H, Monga SP, Wang W, Brown BD, Abrams MT. Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin. Mol Cancer Ther. 2016 Sep;15(9):2143-54.

Dar MS, Singh P, Singh G, Jamwal G, Hussain SS, Rana A, Akhter Y, Monga SP, Dar MJ. Terminal regions of β-catenin are critical for regulating its adhesion and transcription functions. Biochim Biophys Acta. 2016 Sep;1863(9):2345-57.

Stephen J.D. O'Keefe, MBBS, MD, MScKatsidzira L, Ocvirk S, Wilson A, Li J, Mahachi CB, Soni D, DeLany J, Nicholson JK, Zoetendal EG, O'Keefe SJD. Differences in Fecal Gut Microbiota, Short-chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans. Nutr Cancer. 2019 Apr;22:1-12.

Chan YM, Aufreiter S, O'Keefe SJ, O'Connor DL. Switching to a Fibre-rich and Low-fat Diet Increases Colonic Folate Contents Among African Americans. Appl Physiol Nutr Metab. 2019 Feb;44(2):127-32.

Klurfeld DM, Davis CD, Karp RW, Allen-Vercoe E, Chang EB, Chassaing B, Fahey GC Jr, Hamaker BR, Holscher HD, Lampe JW, Marette A, Martens E, O'Keefe SJ, Rose DJ, Saarela M, Schneeman BO, Slavin JL, Sonnenburg JL, Swanson KS, Wu GD, Lynch CJ. Considerations for Best Practices in Studies of Fiber or Other Dietary Compoents and the Intestinal Microbiome. Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1087-97.Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe S, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severity of Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Machicado JD, Gougol A, Paragomi P, O'Keefe SJ, Lee K, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Practice Patterns and Utilization of Tube Feedings in Acute Panreatitis Patients at a Large US Referral Center. Pancreas. 2018 Oct;47(9):1150-55.

O'Keefe SJD, Rakitt T, Ou J, El Hajj II, Blaney E, Vipperla K, Holst JJ, Rehlfeld J. Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity. Clin Transl Gastroenterol. 2017 Aug 3;8(8):e112.

Georgios I. Papachristou, MD, PhD*Párniczky A, Lantos T, Tóth EM, Szakács Z, Gódi S, Hágendorn R, Illés D, Koncz B, Márta K, Mikó A, Mosztbacher D, Németh BC, Pécsi D, Szabó A, Szücs Á, Varjú P, Szentesi A, Darvasi E, Erőss B, Izbéki F, Gajdán L, Halász A, Vincze Á, Szabó I, Pár G, Bajor J, Sarlós P, Czimmer J, Hamvas J, Takács T, Szepes Z, Czakó L, Varga M, Novák J, Bod B, Szepes A, Sümegi J, Papp M, Góg C, Török I, Huang W, Xia Q, Xue P, Li W, Chen W, Shirinskaya NV, Poluektov VL, Shirinskaya AV, Hegyi PJ, Bátovský M, Rodriguez-Oballe JA, Salas IM, Lopez-Diaz J, Dominguez-Munoz JE, Molero X, Pando E, Ruiz-Rebollo ML, Burgueño-Gómez B, Chang YT, Chang MC, Sud A, Moore D, Sutton R, Gougol A, Papachristou GI, Susak YM, Tiuliukin IO, Gomes AP, Oliveira MJ, Aparício DJ, Tantau M, Kurti F, Kovacheva-Slavova M, Stecher SS, Mayerle J, Poropat G, Das K, Marino MV, Capurso G, Małecka-Panas E, Zatorski H, Gasiorowska A, Fabisiak N, Ceranowicz P, Kuśnierz-Cabala B, Carvalho JR, Fernandes SR, Chang JH, Choi EK, Han J, Bertilsson S, Jumaa H, Sandblom G, Kacar

87



Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol. 2018 Jun;188(6):1389-1405.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP. The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model. Gene Expr. 2018 May 18;18(2):135-147.

Thompson MD, Moghe A, Cornuet P, Marino R, Tian J, Wang P, Ma X, Abrams M, Locker J, Monga SP, Nejak-Bowen K. β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis. Hepatology. 2018 Mar;67(3):955-971.

Liu C, Ren YF, Dong J, Ke MY, Ma F, Monga SPS, Wu R, Lv Y, Zhang XF. Activation of SRY accounts for male-specific hepatocarcinogenesis: Implication in gender disparity of hepatocellular carcinoma. Cancer Lett. 2017 Dec 1;410:20-31.

Puliga E, Min Q, Tao J, Zhang R, Pradhan-Sundd T, Poddar M, Singh S, Columbano A, Yu J, Monga SP. Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer. Am J Pathol. 2017 Nov;187(11):2473-2485.

Soto-Gutierrez A, Gough A, Vernetti LA, Taylor DL, Monga SP. Pre-clinical and clinical investigations of metabolic zonation in liver diseases: The potential of microphysiology systems. Exp Biol Med (Maywood). 2017 Oct;242(16):1605-1616.

Kikuchi A, Pradhan-Sundd T, Singh S, Nagarajan S, Loizos N, Monga SP. Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration. Am J Pathol. 2017 Oct;187(10):2273-2287.

Chen ZH, Yu YP, Tao J, Liu S, Tseng G, Nalesnik M, Hamilton R, Bhargava R, Nelson JB, Pennathur A, Monga SP, Luketich JD, Michalopoulos GK, Luo JH. MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice. Gastroenterology. 2017 Oct;153(4):1120-1132.e15.

Preziosi ME, Singh S, Valore EV, Jung G, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload. J Hepatol. 2017 Aug;67(2):360-369.

Chen ZH, Yu YP, Zuo ZH, Nelson JB, Michalopoulos GK, Monga S, Liu S, Tseng G, Luo JH. Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene. Nat Biotechnol. 2017 Jun;35(6):543-550.

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP. Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice. Hepatology. 2017 May;65(5):1581-1599.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma. J Biol Chem. 2016 Dec 16;291(51):26241-26251.

Okabe H, Yang J, Sylakowski K, Yovchev M, Miyagawa Y, Nagarajan S, Chikina M, Thompson M, Oertel M, Baba H, Monga SP, Nejak-Bowen KN. Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice. Hepatology. 2016 Nov;64(5):1652-1666.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP. Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin. Hepatology. 2016 Nov;64(5):1587-1605.

Ganesh S, Koser ML, Cyr WA, Chopda GR, Tao J, Shui X, Ying B, Chen D, Pandya P, Chipumuro E, Siddiquee Z, Craig K, Lai C, Dudek H, Monga SP, Wang W, Brown BD, Abrams MT. Direct Pharmacological Inhibition of β-Catenin by RNA Interference in Tumors of Diverse Origin. Mol Cancer Ther. 2016 Sep;15(9):2143-54.

Dar MS, Singh P, Singh G, Jamwal G, Hussain SS, Rana A, Akhter Y, Monga SP, Dar MJ. Terminal regions of β-catenin are critical for regulating its adhesion and transcription functions. Biochim Biophys Acta. 2016 Sep;1863(9):2345-57.

Stephen J.D. O'Keefe, MBBS, MD, MScKatsidzira L, Ocvirk S, Wilson A, Li J, Mahachi CB, Soni D, DeLany J, Nicholson JK, Zoetendal EG, O'Keefe SJD. Differences in Fecal Gut Microbiota, Short-chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans. Nutr Cancer. 2019 Apr;22:1-12.

Chan YM, Aufreiter S, O'Keefe SJ, O'Connor DL. Switching to a Fibre-rich and Low-fat Diet Increases Colonic Folate Contents Among African Americans. Appl Physiol Nutr Metab. 2019 Feb;44(2):127-32.

Klurfeld DM, Davis CD, Karp RW, Allen-Vercoe E, Chang EB, Chassaing B, Fahey GC Jr, Hamaker BR, Holscher HD, Lampe JW, Marette A, Martens E, O'Keefe SJ, Rose DJ, Saarela M, Schneeman BO, Slavin JL, Sonnenburg JL, Swanson KS, Wu GD, Lynch CJ. Considerations for Best Practices in Studies of Fiber or Other Dietary Compoents and the Intestinal Microbiome. Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1087-97.Dugum M, Gougol A, Paragomi P, Gao X, Matta B, Yazici C, Tang G, Greer P, Pothoulakis I, O'Keefe S, Whitcomb DC, Yadav D, Papachristou GI. Association of Dietary Habits with Severity of Acute Pancreatitis. Curr Dev Nutr. 2018 Oct 8;2(12):nzy075.

Machicado JD, Gougol A, Paragomi P, O'Keefe SJ, Lee K, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Practice Patterns and Utilization of Tube Feedings in Acute Panreatitis Patients at a Large US Referral Center. Pancreas. 2018 Oct;47(9):1150-55.

O'Keefe SJD, Rakitt T, Ou J, El Hajj II, Blaney E, Vipperla K, Holst JJ, Rehlfeld J. Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity. Clin Transl Gastroenterol. 2017 Aug 3;8(8):e112.

Georgios I. Papachristou, MD, PhD*Párniczky A, Lantos T, Tóth EM, Szakács Z, Gódi S, Hágendorn R, Illés D, Koncz B, Márta K, Mikó A, Mosztbacher D, Németh BC, Pécsi D, Szabó A, Szücs Á, Varjú P, Szentesi A, Darvasi E, Erőss B, Izbéki F, Gajdán L, Halász A, Vincze Á, Szabó I, Pár G, Bajor J, Sarlós P, Czimmer J, Hamvas J, Takács T, Szepes Z, Czakó L, Varga M, Novák J, Bod B, Szepes A, Sümegi J, Papp M, Góg C, Török I, Huang W, Xia Q, Xue P, Li W, Chen W, Shirinskaya NV, Poluektov VL, Shirinskaya AV, Hegyi PJ, Bátovský M, Rodriguez-Oballe JA, Salas IM, Lopez-Diaz J, Dominguez-Munoz JE, Molero X, Pando E, Ruiz-Rebollo ML, Burgueño-Gómez B, Chang YT, Chang MC, Sud A, Moore D, Sutton R, Gougol A, Papachristou GI, Susak YM, Tiuliukin IO, Gomes AP, Oliveira MJ, Aparício DJ, Tantau M, Kurti F, Kovacheva-Slavova M, Stecher SS, Mayerle J, Poropat G, Das K, Marino MV, Capurso G, Małecka-Panas E, Zatorski H, Gasiorowska A, Fabisiak N, Ceranowicz P, Kuśnierz-Cabala B, Carvalho JR, Fernandes SR, Chang JH, Choi EK, Han J, Bertilsson S, Jumaa H, Sandblom G, Kacar

88



S, Baltatzis M, Varabei AV, Yeshy V, Chooklin S, Kozachenko A, Veligotsky N, Hegyi P; Hungarian Pancreatic Study Group. Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations. Pancreatology. 2019 Jun;19(4):488-499.

Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10.

Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of bacterial exposure to the endoscopist's face during endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-824.

Smeets XJNM, Knoester I, Grooteman KV, Singh VK, Banks PA, Papachristou GI, Duarte-Rojo A, Robles-Diaz G, Kievit W, Besselink MGH, Verdonk RC, Van Santvoort HC, Drenth JPH, Belias M, Van Geenen EJM; Dutch Pancreatitis Study Group. The association between obesity and outcomes in acute pancreatitis: an individual patient data meta-analysis. Eur J Gastroenterol Hepatol. 2019 Mar;31(3):316-322.

Murthy P, Singhi AD, Ross MA, Loughran P, Paragomi P, Papachristou GI, Whitcomb DC, Zureikat AH, Lotze MT, Zeh Iii HJ, Boone BA. Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine. Front Immunol. 2019 Jan 24;10:28.

Das R, Zeh H, Zureikat A, Slivka A, Papachristou GI. Endoscopic Ultrasound-Guided Creation of a Gastrogastric Conduit After Pancreaticoduodenectomy in a Patient with Prior Roux-en-Y Gastric Bypass. ACG Case Rep J. 2018 Dec 19;5:e100.

Moran RA, García-Rayado G, de la Iglesia-García D, Martínez-Moneo E, Fort-Martorell E, Lauret-Braña E, Concepción-Martín M, Ausania F, Prieto-Martínez C, González-de-Cabo M, Quesada-Vázquez N, Marcaide-Ruiz-de-Apodaca MA, Pajares-Díaz JA, Díaz FC, de-Benito JL, Hinojosa-Guadix J, Marqués-García P, Boadas J, Bajador-Andreu E, Moreno O, Argüelles-Arias F, Martín-Benítez G, Tafur-Sánchez C, Leal-Téllez J, Romero-Mosquera B, Hernaez R, Papachristou GI, Singh VK, de-Madaria E. Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study. United European Gastroenterol J. 2018 Dec;6(10):1508-1518.


Machicado JD, Gougol A, Paragomi P, OʼKeefe SJ, Lee K, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Practice Patterns and Utilization of Tube Feedings in Acute Pancreatitis Patients at a Large US Referral Center. Pancreas. 2018 Oct;47(9):1150-1155.


Lee PJ, Modha K, Chua T, Chak A, Jang D, Lopez R, Gougol A, Papachristou GI, Stevens T. Association of

Statins With Decreased Acute Pancreatitis Severity: A Propensity Score Analysis. J Clin Gastroenterol. 2018 Sep;52(8):742-746.


Singh H, Gougol A, Mounzer R, Yadav D, Koutroumpakis E, Slivka A, Whitcomb DC, Papachristou GI. Which Patients with Mild Acute Pancreatitis Require Prolonged Hospitalization? Clin Transl Gastroenterol. 2017 Dec 7;8(12):e129.

Staudacher JJ, Yazici C, Carroll T, Bauer J, Pang J, Krett N, Xia Y, Wilson A, Papachristou G, Dirmeier A, Kunst C, Whitcomb DC, Fantuzzi G, Jung B. Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target. Sci Rep. 2017 Oct 6;7(1):12786.

Machicado JD, Gougol A, Stello K, Tang G, Park Y, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Acute Pancreatitis Has a Long-term Deleterious Effect on Physical Health Related Quality of Life. Clin Gastroenterol Hepatol. 2017 Sep;15(9):1435-1443.e2.



Singh VK, Gardner TB, Papachristou GI, Rey-Riveiro M, Faghih M, Koutroumpakis E, Afghani E, Acevedo-Piedra NG, Seth N, Sinha A, Quesada-Vázquez N, Moya-Hoyo N, Sánchez-Marin C, Martínez J, Lluís F, Whitcomb DC, Zapater P, de-Madaria E. An international multicenter study of early intravenous fluid administration and outcome in acute pancreatitis. United European Gastroenterol J. 2017 Jun;5(4):491-498.


Vipperla K, Somerville C, Furlan A, Koutroumpakis E, Saul M, Chennat J, Rabinovitz M, Whitcomb DC, Slivka A, Papachristou GI, Yadav D. Clinical Profile and Natural Course in a Large Cohort of Patients With Hypertriglyceridemia and Pancreatitis. J Clin Gastroenterol. 2017 Jan;51(1):77-85.


Umapathy C, Raina A, Saligram S, Tang G, Papachristou GI, Rabinovitz M, Chennat J, Zeh H, Zureikat AH, 89



S, Baltatzis M, Varabei AV, Yeshy V, Chooklin S, Kozachenko A, Veligotsky N, Hegyi P; Hungarian Pancreatic Study Group. Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations. Pancreatology. 2019 Jun;19(4):488-499.

Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures. Gut. 2019 Apr 10.

Johnston ER, Habib-Bein N, Dueker JM, Quiroz B, Corsaro E, Ambrogio M, Kingsley M, Papachristou GI, Kreiss C, Khalid A. Risk of bacterial exposure to the endoscopist's face during endoscopy. Gastrointest Endosc. 2019 Apr;89(4):818-824.

Smeets XJNM, Knoester I, Grooteman KV, Singh VK, Banks PA, Papachristou GI, Duarte-Rojo A, Robles-Diaz G, Kievit W, Besselink MGH, Verdonk RC, Van Santvoort HC, Drenth JPH, Belias M, Van Geenen EJM; Dutch Pancreatitis Study Group. The association between obesity and outcomes in acute pancreatitis: an individual patient data meta-analysis. Eur J Gastroenterol Hepatol. 2019 Mar;31(3):316-322.



Moran RA, García-Rayado G, de la Iglesia-García D, Martínez-Moneo E, Fort-Martorell E, Lauret-Braña E, Concepción-Martín M, Ausania F, Prieto-Martínez C, González-de-Cabo M, Quesada-Vázquez N, Marcaide-Ruiz-de-Apodaca MA, Pajares-Díaz JA, Díaz FC, de-Benito JL, Hinojosa-Guadix J, Marqués-García P, Boadas J, Bajador-Andreu E, Moreno O, Argüelles-Arias F, Martín-Benítez G, Tafur-Sánchez C, Leal-Téllez J, Romero-Mosquera B, Hernaez R, Papachristou GI, Singh VK, de-Madaria E. Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study. United European Gastroenterol J. 2018 Dec;6(10):1508-1518.




Lee PJ, Modha K, Chua T, Chak A, Jang D, Lopez R, Gougol A, Papachristou GI, Stevens T. Association of

Statins With Decreased Acute Pancreatitis Severity: A Propensity Score Analysis. J Clin Gastroenterol. 2018 Sep;52(8):742-746.











Umapathy C, Raina A, Saligram S, Tang G, Papachristou GI, Rabinovitz M, Chennat J, Zeh H, Zureikat AH, 90



Hogg ME, Lee KK, Saul MI, Whitcomb DC, Slivka A, Yadav D. Natural History After Acute Necrotizing Pancreatitis: a Large US Tertiary Care Experience. J Gastrointest Surg. 2016 Nov;20(11):1844-1853.

Razzak A, Smith D, Zahid M, Papachristou G, Khalid A. Effect of quality metric monitoring and colonoscopy performance. Endosc Int Open. 2016 Oct;4(10):E1023-E1027.

Das R, Clarke B, Tang G, Papachristou GI, Whitcomb DC, Slivka A, Yadav D. Endoscopic sphincterotomy (ES) may not alter the natural history of idiopathic recurrent acute pancreatitis (IRAP). Pancreatology. 2016 Sep-Oct;16(5):770-7.

Easler JJ, de-Madaria E, Nawaz H, Moya-Hoyo N, Koutroumpakis E, Rey-Riveiro M, Singh VP, Acevedo-Piedra NG, Whitcomb DC, Yadav D, Papachristou GI. Patients With Sentinel Acute Pancreatitis of Alcoholic Etiology Are at Risk for Organ Failure and Pancreatic Necrosis: A Dual-Center Experience. Pancreas. 2016 Aug;45(7):997-1002.

Koutroumpakis E, Dasyam AK, Furlan A, Slivka A, Gougol A, Zeh HJ 3rd, Lee KK, Zureikat AH, Whitcomb DC, Yadav D, Papachristou GI. Isolated Peripancreatic Necrosis in Acute Pancreatitis Is Infrequent and Leads to Severe Clinical Course Only When Extensive: A Prospective Study From a US Tertiary Center. J Clin Gastroenterol. 2016 Aug;50(7):589-95.

Anna Evans Phillips, MD, MScPhillips AE, Shah N, Borhani AA, Yadav D, Brand RE. Prior History of Pancreatitis Accelerates the Development of Pancreatic Adenocarcinoma. Pancreas. 2018 Nov/Dec;47(10:1262-66.

Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gartner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb, DC, Yadav D. Known Genetic Susceptibility Factors for Chronic Pancreatitis in Patients of European Ancestry are Rare in Patients of African Ancestry. Pancreatology. 2018 May. [Epub ahead of print]

Evans AC, Singhi AD, Zeh HJ Rd, Bahary N, Brand RE. An Unexpected Etiology of Pancreatic Panniculitis: A Case Report. J Pancreat Cancer. 2017;3(1):1-4.

Seaman JB, Evans AC, Sciulli AM, Barnato AE, Sereika SM, Happ MB. Abstracting ICU Nursing Care Quality Data From the Electronic Health Record. West J Nurs Res. 2017 Sep;39(9):1271-1288.

Siobhan Proksell, MD


Mordechai Rabinovitz, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A.

Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10. [Epub ahead of print]

O'Leary JG, Fontana RJ, Brown K, Burton JR Jr, Firpi-Morell R, Muir A, O'Brien C, Rabinovitz M, Reddy R, Ryan R, Shprecher A, Villadiego S, Prabhakar A, Brown RS Jr. Efficacy and Safety of Simeprevir and Sofosbuvir with and without Ribavirin in Subjects with Recurrent Genotype 1 Hepatitis C Postorthotopic Liver Transplant: The Randomized GALAXY Study. Transpl Int. 2017 Feb;30(2):196-208.


Umapathy C, Raina A, Saligram S, Tang G, Papachristou GI, Rabinovitz M, Chennat J, Zeh H, Zureikat AH, Hogg ME, Lee KK, Saul MI, Whitcomb DC, Slivka A, Yadav D. Natural History After Acute Necrotizing Pancreatitis: a Large US Tertiary Care Experience. J Gastrointest Surg. 2016 Nov;20(11):1844-1853.

Lawitz E, Reau N, Hinestrosa F, Rabinovitz M, Schiff E, Sheikh A, Younes Z, Herring R Jr, Reddy KR, Tran T, Bennett M, Nahass R, Yang JC, Lu S, Dvory-Sobol H, Stamm LM, Brainard DM, McHutchison JG, Pearlman B, Shiffman M, Hawkins T, Curry M, Jacobson I. Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial. Gastroenterology. 2016 Nov;151(5):893-901.

Kowdley KV, Nelson DR, Lalezari JP, Box T, Gitlin N, Poleynard G, Rabinovitz M, Ravendhran N, Sheikh AM, Siddique A, Bhore R, Noviello S, Rana K. On-treatment HCV RNA as a predictor of sustained virological response in HCV genotype 3-infected patients treated with daclatasvir and sofosbuvir. Liver Int. 2016 Nov;36(11):1611-1618.

Vikrant P. Rachakonda, MDRachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patietns with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.

Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Humar A, Sood P, Rachakonda V, Dunn MA, Tevar AD. Gait Speed and Grip Strength are Associated with Dropping Out of the Liver Transplant Waiting List. Trasnplant Proc. 2019 Apr;51(3):794-797.




91



Hogg ME, Lee KK, Saul MI, Whitcomb DC, Slivka A, Yadav D. Natural History After Acute Necrotizing Pancreatitis: a Large US Tertiary Care Experience. J Gastrointest Surg. 2016 Nov;20(11):1844-1853.

Razzak A, Smith D, Zahid M, Papachristou G, Khalid A. Effect of quality metric monitoring and colonoscopy performance. Endosc Int Open. 2016 Oct;4(10):E1023-E1027.




Anna Evans Phillips, MD, MScPhillips AE, Shah N, Borhani AA, Yadav D, Brand RE. Prior History of Pancreatitis Accelerates the Development of Pancreatic Adenocarcinoma. Pancreas. 2018 Nov/Dec;47(10:1262-66.

Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gartner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb, DC, Yadav D. Known Genetic Susceptibility Factors for Chronic Pancreatitis in Patients of European Ancestry are Rare in Patients of African Ancestry. Pancreatology. 2018 May. [Epub ahead of print]

Evans AC, Singhi AD, Zeh HJ Rd, Bahary N, Brand RE. An Unexpected Etiology of Pancreatic Panniculitis: A Case Report. J Pancreat Cancer. 2017;3(1):1-4.

Seaman JB, Evans AC, Sciulli AM, Barnato AE, Sereika SM, Happ MB. Abstracting ICU Nursing Care Quality Data From the Electronic Health Record. West J Nurs Res. 2017 Sep;39(9):1271-1288.

Siobhan Proksell, MD


Mordechai Rabinovitz, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A.

Integrating Next-generation Sequencing to Endoscopic Retrograde cholangiopancreatography (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patietns with Malignant Bile Duct Strictures. Gut. 2019 Apr 10. [Epub ahead of print]

O'Leary JG, Fontana RJ, Brown K, Burton JR Jr, Firpi-Morell R, Muir A, O'Brien C, Rabinovitz M, Reddy R, Ryan R, Shprecher A, Villadiego S, Prabhakar A, Brown RS Jr. Efficacy and Safety of Simeprevir and Sofosbuvir with and without Ribavirin in Subjects with Recurrent Genotype 1 Hepatitis C Postorthotopic Liver Transplant: The Randomized GALAXY Study. Transpl Int. 2017 Feb;30(2):196-208.



Lawitz E, Reau N, Hinestrosa F, Rabinovitz M, Schiff E, Sheikh A, Younes Z, Herring R Jr, Reddy KR, Tran T, Bennett M, Nahass R, Yang JC, Lu S, Dvory-Sobol H, Stamm LM, Brainard DM, McHutchison JG, Pearlman B, Shiffman M, Hawkins T, Curry M, Jacobson I. Efficacy of Sofosbuvir, Velpatasvir, and GS-9857 in Patients With Genotype 1 Hepatitis C Virus Infection in an Open-Label, Phase 2 Trial. Gastroenterology. 2016 Nov;151(5):893-901.

Kowdley KV, Nelson DR, Lalezari JP, Box T, Gitlin N, Poleynard G, Rabinovitz M, Ravendhran N, Sheikh AM, Siddique A, Bhore R, Noviello S, Rana K. On-treatment HCV RNA as a predictor of sustained virological response in HCV genotype 3-infected patients treated with daclatasvir and sofosbuvir. Liver Int. 2016 Nov;36(11):1611-1618.

Vikrant P. Rachakonda, MDRachakonda V, Argemi J, Borhani AA, Bataller R, Tevar A, Behari J. Reduced Serum Sphingolipids Constitute a Molecular Signature of Malnutrition in Hospitalized Patietns with Decompensated Cirrhosis. Clin Transl Gastroenterol. 2019 Mar;10(3):e00013.

Kulkarni SS, Chen H, Josbeno DA, Schmotzer A, Hughes C, Humar A, Sood P, Rachakonda V, Dunn MA, Tevar AD. Gait Speed and Grip Strength are Associated with Dropping Out of the Liver Transplant Waiting List. Trasnplant Proc. 2019 Apr;51(3):794-797.




92



Shari S. Rogal, MD, MPHRogal SS, Beste LA, Youk A, Fine MJ, Ketterer B, Zhang H, Leipertz S, Chartier M, Good CB, Kraemer KL, Chinman M, Morgan T, Gellad WF. Characteristics of Opioid Prescriptions to Veterans with Cirrhosis. Clin Gastroenterol Hepatol. 2019 May;17(6):1165-74.

Rogal SS, Yakovchenko V, Waltz TJ, Powell BJ, Gonzalez R, Park A, Chartier M, Ross D, Morgan TR, Kirchner JE, Proctor EK, Chinman MJ. Logitudinal Assessment of the Association Between Implementation Strategy Use and the Uptake of Hepatitis C Treatment: Year 2. Implement Sci. 2019 Apr 8;14(1):36.

Woodward EN, Matthieu MM, Uchendu US, Rogal S, Kirchner JE. The health equity implementation framework: proposal and preliminary study of hepatitis C virus treatment. Implement Sci. 2019 Mar 12;14(1):26.

Chinman M, Gellad WF, McCarthy S, Gordon AJ, Rogal S, Mor MK, Hausmann LRM. Protocol for evaluating the nationwide implementation of the VA Stratification Tool for Opioid Risk Management (STORM). Implement Sci. 2019 Jan 18;14(1):5.

Rogal SS, Udawatta V, Akpan I, Moghe A, Chidi A, Shetty A, Szigethy E, Bielefeldt K, DiMartini A. Risk factors for hospitalizations among patients with cirrhosis: A prospective cohort study. PLoS One. 2017 Nov 17;12(11):e0187176.

Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices. Clin Transplant. 2017 Dec;31(12).


Rogal SS, Yakovchenko V, Waltz TJ, Powell BJ, Kirchner JE, Proctor EK, Gonzalez R, Park A, Ross D, Morgan TR, Chartier M, Chinman MJ. The association between implementation strategy use and the uptake of hepatitis C treatment in a national sample. Implement Sci. 2017 May 11;12(1):60.



Savreet Sarkaria, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatogrphy (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Marc B. Schwartz, MDAnderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz Md, Regueiro M, Binion D. Low Rates of Dermatoligic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-39.

Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Beween Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun;24(7):1380-88.

Johnson CM, Hartman DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Al Hashash J, Barrie A, Pfanner TP, Dunn M, Koutroubakis IE, Binion DG. Epithelioid Granulomas Associate With Increased Severity and Progression of Crohn's Disease. Based on 6-Year Follow-Up. Clin Gastroenterol Hepatol. 2018 Jun;16(6):900-907.e1.







Jiang J, Click B, Anderson AM, Koutroubakis IE, Rivers CR, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A, Regueiro M, Chang CC, Binion DG. Group-Based Trajectory Modeling of Healthcare Financial Charges in Inflammatory Bowel Disease: A Comprehensive Phenotype. Clin Transl Gastroenterol. 2016 Jul

93



Shari S. Rogal, MD, MPHRogal SS, Beste LA, Youk A, Fine MJ, Ketterer B, Zhang H, Leipertz S, Chartier M, Good CB, Kraemer KL, Chinman M, Morgan T, Gellad WF. Characteristics of Opioid Prescriptions to Veterans with Cirrhosis. Clin Gastroenterol Hepatol. 2019 May;17(6):1165-74.

Rogal SS, Yakovchenko V, Waltz TJ, Powell BJ, Gonzalez R, Park A, Chartier M, Ross D, Morgan TR, Kirchner JE, Proctor EK, Chinman MJ. Logitudinal Assessment of the Association Between Implementation Strategy Use and the Uptake of Hepatitis C Treatment: Year 2. Implement Sci. 2019 Apr 8;14(1):36.

Woodward EN, Matthieu MM, Uchendu US, Rogal S, Kirchner JE. The health equity implementation framework: proposal and preliminary study of hepatitis C virus treatment. Implement Sci. 2019 Mar 12;14(1):26.

Chinman M, Gellad WF, McCarthy S, Gordon AJ, Rogal S, Mor MK, Hausmann LRM. Protocol for evaluating the nationwide implementation of the VA Stratification Tool for Opioid Risk Management (STORM). Implement Sci. 2019 Jan 18;14(1):5.


Fleming JN, Lai JC, Te HS, Said A, Spengler EK, Rogal SS. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices. Clin Transplant. 2017 Dec;31(12).


Rogal SS, Yakovchenko V, Waltz TJ, Powell BJ, Kirchner JE, Proctor EK, Gonzalez R, Park A, Ross D, Morgan TR, Chartier M, Chinman MJ. The association between implementation strategy use and the uptake of hepatitis C treatment in a national sample. Implement Sci. 2017 May 11;12(1):60.



Savreet Sarkaria, MDSinghi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Oori NP, Geller D, Tsung A, Zureikate AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating Next-generation Sequencing to Endoscopic Retrograde Cholangiopancreatogrphy (ERCP)-obtained Biliary Specimens Improves the Detection and Management of Patients with Malignant Bile Duct Strictures. Gut. 2019 Apr 10 [Epub ahead of print].

Marc B. Schwartz, MDAnderson A, Ferris LK, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn M, Barrie A, Schwartz Md, Regueiro M, Binion D. Low Rates of Dermatoligic Care and Skin Cancer Screening Among Inflammatory Bowel Disease Patients. Dig Dis Sci. 2018 Oct;63(10):2729-39.

Anderson A, Click B, Ramos-Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A 3rd, Regueiro M, Binion DG. The Association Beween Sustained Poor Quality of Life and Future Opioid Use in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Jun;24(7):1380-88.

Johnson CM, Hartman DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Al Hashash J, Barrie A, Pfanner TP, Dunn M, Koutroubakis IE, Binion DG. Epithelioid Granulomas Associate With Increased Severity and Progression of Crohn's Disease. Based on 6-Year Follow-Up. Clin Gastroenterol Hepatol. 2018 Jun;16(6):900-907.e1.







Jiang J, Click B, Anderson AM, Koutroubakis IE, Rivers CR, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A, Regueiro M, Chang CC, Binion DG. Group-Based Trajectory Modeling of Healthcare Financial Charges in Inflammatory Bowel Disease: A Comprehensive Phenotype. Clin Transl Gastroenterol. 2016 Jul

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Obaid S. Shaikh, MDButt AA, Yan P, Aslam S, Shaikh OS, Abou-Samra AB. Hepatitis C Virus Treatment with Directly Acting Agents Reduces the Risk of Incident Diabetes - Results from ERCHIVES. Clin Infect Dis. 2019 Apr 12.

Butt AA, Yan P, Shuaib A, Abou-Samra AB, Shaikh OS, Freiberg MS. Direct-Acting Antiviral Therapy for HCV Infection Is Associated With a Reduced Risk of Cardiovascular Disease Events. Gastroenterology. 2019 Mar;156(4):987-996.e8.

Butt AA, Yan P, Lo Re Iii V, Shaikh OS, Ross DB. Trends in Treatment Uptake and Provider Specialty for Hepatitis C Virus (HCV) Infection in the Veterans Affairs Healthcare System: Results From the Electronically Retrieved Cohort of HCV-Infected Veterans (ERCHIVES). Clin Infect Dis. 2019 Feb 15;68(5):857-859.

Li DK, Ren Y, Fierer DS, Rutledge S, Shaikh OS, Lo Re V 3rd, Simon T, Abou-Samra AB, Chung RT, Butt AA. The short-term incidence of hepatocellular carcinoma is not increased after hepatitis C treatment with direct-acting antivirals: An ERCHIVES study. Hepatology. 2018 Jun;67(6):2244-2253.

Butt AA, Yan P, Shaikh OS, Abou-Samra AB. Hepatitis B reactivation and outcomes in persons treated with directly acting antiviral agents against hepatitis C virus: results from ERCHIVES. Aliment Pharmacol Ther. 2018 Feb;47(3):412-420.

Koch DG, Speiser JL, Durkalski V, Fontana RJ, Davern T, McGuire B, Stravitz RT, Larson AM, Liou I, Fix O, Schilsky ML, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Brown RS, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hanje AJ, Olson J, Subramanian RM, Karvellas C, Hameed B, Sherker AH, Lee WM, Reuben A. The Natural History of Severe Acute Liver Injury. Am J Gastroenterol. 2017 Sep;112(9):1389-1396.

Ho SB, Monto A, Peyton A, Kaplan DE, Byrne S, Moon S, Copans A, Rossaro L, Roy A, Le H, Dvory-Sobol H, Zhu Y, Brainard DM, Guyer W, Shaikh O, Fuchs M, Morgan TR; VALOR study team. Efficacy of Sofosbuvir Plus Ribavirin in Veterans With Hepatitis C Virus Genotype 2 Infection, Compensated Cirrhosis, and Multiple Comorbidities. Clin Gastroenterol Hepatol. 2017 Feb;15(2):282-288.

Butt AA, Ren Y, Marks K, Shaikh OS, Sherman KE; ERCHIVES study. Do directly acting antiviral agents for HCV increase the risk of hepatic decompensation and decline in renal function? Results from ERCHIVES. Aliment Pharmacol Ther. 2017 Jan;45(1):150-159.

Fontana RJ, Engle RE, Scaglione S, Araya V, Shaikh O, Tillman H, Attar N, Purcell RH, Lee WM; US Acute Liver Failure Study Group. The role of hepatitis E virus infection in adult Americans with acute liver failure. Hepatology. 2016 Dec;64(6):1870-1880.

Rogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N,

Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A. Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS One. 2016 Nov 7;11(11):e0165517.

Butt AA, Yan P, Marks K, Shaikh OS, Sherman KE; ERCHIVES Study Team. Adding ribavirin to newer DAA regimens does not affect SVR rates in HCV genotype 1 infected persons: results from ERCHIVES. Aliment Pharmacol Ther. 2016 Oct;44(7):728-37.


Butt AA, Yan P, Shaikh OS, Chung RT, Sherman KE; ERCHIVES study. Treatment adherence and virological response rates in hepatitis C virus infected persons treated with sofosbuvir-based regimens: results from ERCHIVES. Liver Int. 2016 Sep;36(9):1275-83.

Harkirat Singh, MBBSSingh H, Gougol A, Mounzer R, Yadav D, Koutroumpakis E, Slivka A, Whitcomb DC, Papachristou GI. Which Patients with Mild Acute Pancreatitis Require Prolonged Hospitalization? Clin Transl Gastroenterol. 2017 Dec 7;8(12):e129.

Adam Slivka, MD, PhDMuniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.

Greer JB, Greer P, Sandhu BS, Alkaade S, Wilcox CM, Anderson MA, Sherman S, Gardner TB, Lewis MD, Guda NM, Muniraj T, Conwell D, Cote GA, Forsmark CE, Banks PA, Tang G, Stello K, Gelrud A, Brand RE, Slivka A, Whitcomb DC, Yadav D. Nutrition and Inflammatory Biomarkers in Chronic Pancreatitis Patients. Nutr Clin Pract. 2019 Jun;34(3):387-399.


Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct

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Obaid S. Shaikh, MDButt AA, Yan P, Aslam S, Shaikh OS, Abou-Samra AB. Hepatitis C Virus Treatment with Directly Acting Agents Reduces the Risk of Incident Diabetes - Results from ERCHIVES. Clin Infect Dis. 2019 Apr 12.

Butt AA, Yan P, Shuaib A, Abou-Samra AB, Shaikh OS, Freiberg MS. Direct-Acting Antiviral Therapy for HCV Infection Is Associated With a Reduced Risk of Cardiovascular Disease Events. Gastroenterology. 2019 Mar;156(4):987-996.e8.

Butt AA, Yan P, Lo Re Iii V, Shaikh OS, Ross DB. Trends in Treatment Uptake and Provider Specialty for Hepatitis C Virus (HCV) Infection in the Veterans Affairs Healthcare System: Results From the Electronically Retrieved Cohort of HCV-Infected Veterans (ERCHIVES). Clin Infect Dis. 2019 Feb 15;68(5):857-859.

Li DK, Ren Y, Fierer DS, Rutledge S, Shaikh OS, Lo Re V 3rd, Simon T, Abou-Samra AB, Chung RT, Butt AA. The short-term incidence of hepatocellular carcinoma is not increased after hepatitis C treatment with direct-acting antivirals: An ERCHIVES study. Hepatology. 2018 Jun;67(6):2244-2253.

Butt AA, Yan P, Shaikh OS, Abou-Samra AB. Hepatitis B reactivation and outcomes in persons treated with directly acting antiviral agents against hepatitis C virus: results from ERCHIVES. Aliment Pharmacol Ther. 2018 Feb;47(3):412-420.

Koch DG, Speiser JL, Durkalski V, Fontana RJ, Davern T, McGuire B, Stravitz RT, Larson AM, Liou I, Fix O, Schilsky ML, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Brown RS, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hanje AJ, Olson J, Subramanian RM, Karvellas C, Hameed B, Sherker AH, Lee WM, Reuben A. The Natural History of Severe Acute Liver Injury. Am J Gastroenterol. 2017 Sep;112(9):1389-1396.

Ho SB, Monto A, Peyton A, Kaplan DE, Byrne S, Moon S, Copans A, Rossaro L, Roy A, Le H, Dvory-Sobol H, Zhu Y, Brainard DM, Guyer W, Shaikh O, Fuchs M, Morgan TR; VALOR study team. Efficacy of Sofosbuvir Plus Ribavirin in Veterans With Hepatitis C Virus Genotype 2 Infection, Compensated Cirrhosis, and Multiple Comorbidities. Clin Gastroenterol Hepatol. 2017 Feb;15(2):282-288.

Butt AA, Ren Y, Marks K, Shaikh OS, Sherman KE; ERCHIVES study. Do directly acting antiviral agents for HCV increase the risk of hepatic decompensation and decline in renal function? Results from ERCHIVES. Aliment Pharmacol Ther. 2017 Jan;45(1):150-159.

Fontana RJ, Engle RE, Scaglione S, Araya V, Shaikh O, Tillman H, Attar N, Purcell RH, Lee WM; US Acute Liver Failure Study Group. The role of hepatitis E virus infection in adult Americans with acute liver failure. Hepatology. 2016 Dec;64(6):1870-1880.

Rogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N,

Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A. Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS One. 2016 Nov 7;11(11):e0165517.

Butt AA, Yan P, Marks K, Shaikh OS, Sherman KE; ERCHIVES Study Team. Adding ribavirin to newer DAA regimens does not affect SVR rates in HCV genotype 1 infected persons: results from ERCHIVES. Aliment Pharmacol Ther. 2016 Oct;44(7):728-37.


Butt AA, Yan P, Shaikh OS, Chung RT, Sherman KE; ERCHIVES study. Treatment adherence and virological response rates in hepatitis C virus infected persons treated with sofosbuvir-based regimens: results from ERCHIVES. Liver Int. 2016 Sep;36(9):1275-83.

Harkirat Singh, MBBSSingh H, Gougol A, Mounzer R, Yadav D, Koutroumpakis E, Slivka A, Whitcomb DC, Papachristou GI. Which Patients with Mild Acute Pancreatitis Require Prolonged Hospitalization? Clin Transl Gastroenterol. 2017 Dec 7;8(12):e129.

Adam Slivka, MD, PhDMuniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.



Singhi AD, Nikiforova MN, Chennat J, Papachristou GI, Khalid A, Rabinovitz M, Das R, Sarkaria S, Ayasso MS, Wald AI, Monaco SE, Nalesnik M, Ohori NP, Geller D, Tsung A, Zureikat AH, Zeh H, Marsh JW, Hogg M, Lee K, Bartlett DL, Pingpank JF, Humar A, Bahary N, Dasyam AK, Brand R, Fasanella KE, McGrath K, Slivka A. Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct

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strictures. Gut. 2019 Apr 10.

Friedberg S, Slivka A, Dasyam A, Yadav D. Chronic Pancreatitis with Spontaneously Disappearing Calcifications. ACG Case Rep J. 2018 Dec 5;5:e94.






Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D. Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry. Pancreatology. 2018 May 19.




Gougol A, Dugum M, Dudekula A, Greer P, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Clinical outcomes of isolated renal failure compared to other forms of organ failure in patients with severe acute

pancreatitis. World J Gastroenterol. 2017 Aug 7;23(29):5431-5437.



Magge D, Steve J, Novak S, Slivka A, Hogg M, Zureikat A, Zeh HJ 3rd. Performing the Difficult Cholecystectomy Using Combined Endoscopic and Robotic Techniques: How I Do It. J Gastrointest Surg. 2017 Mar;21(3):583-589.








Koutroumpakis E, Dasyam AK, Furlan A, Slivka A, Gougol A, Zeh HJ 3rd, Lee KK, Zureikat AH, Whitcomb DC, 97



strictures. Gut. 2019 Apr 10.











Gougol A, Dugum M, Dudekula A, Greer P, Slivka A, Whitcomb DC, Yadav D, Papachristou GI. Clinical outcomes of isolated renal failure compared to other forms of organ failure in patients with severe acute

pancreatitis. World J Gastroenterol. 2017 Aug 7;23(29):5431-5437.



Magge D, Steve J, Novak S, Slivka A, Hogg M, Zureikat A, Zeh HJ 3rd. Performing the Difficult Cholecystectomy Using Combined Endoscopic and Robotic Techniques: How I Do It. J Gastrointest Surg. 2017 Mar;21(3):583-589.








Koutroumpakis E, Dasyam AK, Furlan A, Slivka A, Gougol A, Zeh HJ 3rd, Lee KK, Zureikat AH, Whitcomb DC, 98



Yadav D, Papachristou GI. Isolated Peripancreatic Necrosis in Acute Pancreatitis Is Infrequent and Leads to Severe Clinical Course Only When Extensive: A Prospective Study From a US Tertiary Center. J Clin Gastroenterol. 2016 Aug;50(7):589-95.

Eva M. Szigethy, MD, PhDPark KT, Ehrlich OG, Allen JI, Meadows P, Szigethy EM, Henrichsen K, Kim SC, Lawton RC, Murphy SM, Regueiro M, Rubin DT, Engel-Nitz NM, Heller CA. The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn's & Colitis Foundation. Inflamm Bowel Dis. 2019 May 21. [Epub ahead of print]

Oser M, Wallace ML, Solano F, Szigethy EM. Guided Digital Cognitive Behavioral Program for Anxiety in Primary Care: Propensity-Matched Controlled Trial. JMIR Ment Health. 2019 Apr 4;6(4):e11981.


Regueiro M, Click B, Anderson A, Shrank W, Kogan J, McAnallen S, Szigethy E. Reduced Unplanned Care and Disease Activity and Increased Quality of Life After Patient Enrollment in an Inflammatory Bowel Disease Medical Home. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1777-1785.

Yu JS, Szigethy E, Wallace M, Solano F, Oser M. Implementation of a Guided, Digital Cognitive Behavioral Program for Anxiety in Primary Care: Preliminary Findings of Engagement and Effectiveness. Telemed J E Health. 2018 Nov;24(11):870-878.

Stapersma L, van den Brink G, van der Ende J, Szigethy EM, Beukers R, Korpershoek TA, Theuns-Valks SDM, Hillegers MHJ, Escher JC, Utens EMWJ. Effectiveness of Disease-Specific Cognitive Behavioral Therapy on Anxiety, Depression, and Quality of Life in Youth With Inflammatory Bowel Disease: A Randomized Controlled Trial. J Pediatr Psychol. 2018 Oct 1;43(9):967-980.

Chablani SV, Ramos-Rivers C, Binion DG, Szigethy E. Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2018 Sep;63(9):2482-2484.

Stapersma L, van den Brink G, Szigethy EM, Escher JC, Utens EMWJ. Systematic review with meta-analysis: anxiety and depression in children and adolescents with inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Sep;48(5):496-506.

Szigethy E, Solano F, Wallace M, Perry DL, Morrell L, Scott K, Bell MJ, Oser M. A study protocol for a non-randomised comparison trial evaluating the feasibility and effectiveness of a mobile cognitive-behavioural programme with integrated coaching for anxious adults in primary care. BMJ Open. 2018 Jan 13;8(1):e019108.





Regueiro M, Click B, Holder D, Shrank W, McAnallen S, Szigethy E. Constructing an Inflammatory Bowel Disease Patient-Centered Medical Home. Clin Gastroenterol Hepatol. 2017 Aug;15(8):1148-1153.e4.


Keerthy D, Youk A, Srinath AI, Malas N, Bujoreanu S, Bousvaros A, Keljo D, DeMaso DR, Szigethy EM. Effect of Psychotherapy on Health Care Utilization in Children With Inflammatory Bowel Disease and Depression. J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):658-664.


Regueiro MD, McAnallen SE, Greer JB, Perkins SE, Ramalingam S, Szigethy E. The Inflammatory Bowel Disease Specialty Medical Home: A New Model of Patient-centered Care. Inflamm Bowel Dis. 2016 Aug;22(8):1971-80.

David C. Whitcomb, MD, PhDBurbridge C, Randall JA, Sanchez RJ, Dansky H, Symonds T, Girman CJ, Strayer JA, Selk KL, Whitcomb DC, Kershaw EE. Symptoms and Dietary Impact in Hypertriglyceridemia-Associated Pancreatitis: Development and Content Validity of Two New Measures. Pharmacoecon Open. 2019 Jun 27.


Muniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.

Lasher D, Szabó A, Masamune A, Chen JM, Xiao X, Whitcomb DC, Barmada MM, Ewers M, Ruffert C, Paliwal S, Issarapu P, Bhaskar S, Mani KR, Chandak GR, Laumen H, Masson E, Kume K, Hamada S, Nakano E, Seltsam K, Bugert P, Müller T, Groneberg DA, Shimosegawa T, Rosendahl J, Férec C, Lowe ME, Witt H, Sahin-Tóth M. Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis. Am J Gastroenterol. 2019 Jun;114(6):974-983.

Schwarzenberg SJ, Uc A, Zimmerman B, Wilschanski M, Wilcox CM, Whitcomb DC, Werlin SL, Troendle D, Tang G, Slivka A, Singh VK, Sherman S, Shah U, Sandhu BS, Romagnuolo J, Rhee S, Pohl JF, Perito ER, Ooi CY, Nathan JD, Muniraj T, Morinville VD, McFerron B, Mascarenhas M, Maqbool A, Liu Q, Lin TK, Lewis M,

99



Yadav D, Papachristou GI. Isolated Peripancreatic Necrosis in Acute Pancreatitis Is Infrequent and Leads to Severe Clinical Course Only When Extensive: A Prospective Study From a US Tertiary Center. J Clin Gastroenterol. 2016 Aug;50(7):589-95.

Eva M. Szigethy, MD, PhDPark KT, Ehrlich OG, Allen JI, Meadows P, Szigethy EM, Henrichsen K, Kim SC, Lawton RC, Murphy SM, Regueiro M, Rubin DT, Engel-Nitz NM, Heller CA. The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn's & Colitis Foundation. Inflamm Bowel Dis. 2019 May 21. [Epub ahead of print]

Oser M, Wallace ML, Solano F, Szigethy EM. Guided Digital Cognitive Behavioral Program for Anxiety in Primary Care: Propensity-Matched Controlled Trial. JMIR Ment Health. 2019 Apr 4;6(4):e11981.


Regueiro M, Click B, Anderson A, Shrank W, Kogan J, McAnallen S, Szigethy E. Reduced Unplanned Care and Disease Activity and Increased Quality of Life After Patient Enrollment in an Inflammatory Bowel Disease Medical Home. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1777-1785.

Yu JS, Szigethy E, Wallace M, Solano F, Oser M. Implementation of a Guided, Digital Cognitive Behavioral Program for Anxiety in Primary Care: Preliminary Findings of Engagement and Effectiveness. Telemed J E Health. 2018 Nov;24(11):870-878.

Stapersma L, van den Brink G, van der Ende J, Szigethy EM, Beukers R, Korpershoek TA, Theuns-Valks SDM, Hillegers MHJ, Escher JC, Utens EMWJ. Effectiveness of Disease-Specific Cognitive Behavioral Therapy on Anxiety, Depression, and Quality of Life in Youth With Inflammatory Bowel Disease: A Randomized Controlled Trial. J Pediatr Psychol. 2018 Oct 1;43(9):967-980.

Chablani SV, Ramos-Rivers C, Binion DG, Szigethy E. Depressive Symptoms Predict Anti-tumor Necrosis Factor Therapy Noncompliance and Healthcare Utilization in Patients with Inflammatory Bowel Disease. Dig Dis Sci. 2018 Sep;63(9):2482-2484.

Stapersma L, van den Brink G, Szigethy EM, Escher JC, Utens EMWJ. Systematic review with meta-analysis: anxiety and depression in children and adolescents with inflammatory bowel disease. Aliment Pharmacol Ther. 2018 Sep;48(5):496-506.

Szigethy E, Solano F, Wallace M, Perry DL, Morrell L, Scott K, Bell MJ, Oser M. A study protocol for a non-randomised comparison trial evaluating the feasibility and effectiveness of a mobile cognitive-behavioural programme with integrated coaching for anxious adults in primary care. BMJ Open. 2018 Jan 13;8(1):e019108.





Regueiro M, Click B, Holder D, Shrank W, McAnallen S, Szigethy E. Constructing an Inflammatory Bowel Disease Patient-Centered Medical Home. Clin Gastroenterol Hepatol. 2017 Aug;15(8):1148-1153.e4.


Keerthy D, Youk A, Srinath AI, Malas N, Bujoreanu S, Bousvaros A, Keljo D, DeMaso DR, Szigethy EM. Effect of Psychotherapy on Health Care Utilization in Children With Inflammatory Bowel Disease and Depression. J Pediatr Gastroenterol Nutr. 2016 Dec;63(6):658-664.


Regueiro MD, McAnallen SE, Greer JB, Perkins SE, Ramalingam S, Szigethy E. The Inflammatory Bowel Disease Specialty Medical Home: A New Model of Patient-centered Care. Inflamm Bowel Dis. 2016 Aug;22(8):1971-80.

David C. Whitcomb, MD, PhDBurbridge C, Randall JA, Sanchez RJ, Dansky H, Symonds T, Girman CJ, Strayer JA, Selk KL, Whitcomb DC, Kershaw EE. Symptoms and Dietary Impact in Hypertriglyceridemia-Associated Pancreatitis: Development and Content Validity of Two New Measures. Pharmacoecon Open. 2019 Jun 27.


Muniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.

Lasher D, Szabó A, Masamune A, Chen JM, Xiao X, Whitcomb DC, Barmada MM, Ewers M, Ruffert C, Paliwal S, Issarapu P, Bhaskar S, Mani KR, Chandak GR, Laumen H, Masson E, Kume K, Hamada S, Nakano E, Seltsam K, Bugert P, Müller T, Groneberg DA, Shimosegawa T, Rosendahl J, Férec C, Lowe ME, Witt H, Sahin-Tóth M. Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis. Am J Gastroenterol. 2019 Jun;114(6):974-983.


100



Husain SZ, Himes R, Heyman MB, Guda N, Gonska T, Giefer MJ, Gelrud A, Gariepy CE, Gardner TB, Freedman SD, Forsmark CE, Fishman DS, Cote GA, Conwell D, Brand RE, Bellin M, Barth B, Banks PA, Anderson MA, Amann ST, Alkaade S, Abu-El-Haija M, Abberbock JN, Lowe ME, Yadav D. Chronic Pancreatitis: Pediatric and Adult Cohorts Show Similarities in Disease Progress Despite Different Risk Factors. J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):566-573.


Orlova E, Yeh A, Shi M, Firek B, Ranganathan S; 23andMe Research Team, Whitcomb DC, Finegold DN, Ferrell RE, Barmada MM, Marazita ML, Hinds DA, Shaffer JR, Morowitz MJ. Genetic association and differential expression of PITX2 with acute appendicitis. Hum Genet. 2019 Jan;138(1):37-47.


Hart PA, Andersen DK, Mather KJ, Castonguay AC, Bajaj M, Bellin MD, Bradley D, Contreras N, Habtezion A, Korc M, Kudva Y, Petrov MS, Whitcomb DC, Yadav D, Yuan Y, Rinaudo JAS, Srivastava S, Serrano J, Goodarzi MO; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1239-1243



Shelton CA, Umapathy C, Stello K, Yadav D, Whitcomb DC. Hereditary Pancreatitis in the United States: Survival and Rates of Pancreatic Cancer. Am J Gastroenterol. 2018 Sep;113(9):1376.



Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D. Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry. Pancreatology. 2018 May 19. [Epub ahead of print]







Jalaly NY, Moran RA, Fargahi F, Khashab MA, Kamal A, Lennon AM, Walsh C, Makary MA, Whitcomb DC, Yadav D, Cebotaru L, Singh VK. An Evaluation of Factors Associated With Pathogenic PRSS1, SPINK1, CTFR, and/or CTRC Genetic Variants in Patients With Idiopathic Pancreatitis. Am J Gastroenterol. 2017 Aug;112(8):1320-1329.


Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D. Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities. Am J Gastroenterol. 2017 Apr;112(4):633-642.


Vipperla K, Somerville C, Furlan A, Koutroumpakis E, Saul M, Chennat J, Rabinovitz M, Whitcomb DC, Slivka A, Papachristou GI, Yadav D. Clinical Profile and Natural Course in a Large Cohort of Patients With

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Orlova E, Yeh A, Shi M, Firek B, Ranganathan S; 23andMe Research Team, Whitcomb DC, Finegold DN, Ferrell RE, Barmada MM, Marazita ML, Hinds DA, Shaffer JR, Morowitz MJ. Genetic association and differential expression of PITX2 with acute appendicitis. Hum Genet. 2019 Jan;138(1):37-47.


Hart PA, Andersen DK, Mather KJ, Castonguay AC, Bajaj M, Bellin MD, Bradley D, Contreras N, Habtezion A, Korc M, Kudva Y, Petrov MS, Whitcomb DC, Yadav D, Yuan Y, Rinaudo JAS, Srivastava S, Serrano J, Goodarzi MO; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1239-1243






Phillips AE, LaRusch J, Greer P, Abberbock J, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Brand RE, Conwell D, Coté GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis M, Money ME, Muniraj T, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Wilcox CM, Whitcomb DC, Yadav D. Known genetic susceptibility factors for chronic pancreatitis in patients of European ancestry are rare in patients of African ancestry. Pancreatology. 2018 May 19. [Epub ahead of print]









Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D. Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities. Am J Gastroenterol. 2017 Apr;112(4):633-642.


Vipperla K, Somerville C, Furlan A, Koutroumpakis E, Saul M, Chennat J, Rabinovitz M, Whitcomb DC, Slivka A, Papachristou GI, Yadav D. Clinical Profile and Natural Course in a Large Cohort of Patients With

102



Hypertriglyceridemia and Pancreatitis. J Clin Gastroenterol. 2017 Jan;51(1):77-85.




Wassef W, DeWitt J, McGreevy K, Wilcox M, Whitcomb D, Yadav D, Amann S, Mishra G, Alkaade S, Romagnuolo J, Stevens T, Vargo J, Gardner T, Singh V, Park W, Hartigan C, Barton B, Bova C. Pancreatitis Quality of Life Instrument: A Psychometric Evaluation. Am J Gastroenterol. 2016 Aug;111(8):1177-86.




Dhiraj Yadav, MD, MPHMuniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.




Wu BU, Batech M, Dong EY, Duan L, Yadav D, Chen W. Influence of Ambulatory Triglyceride Levels on Risk of Recurrence in Patients with Hypertriglyceridemic Pancreatitis. Dig Dis Sci. 2019 Mar;64(3):890-897.

Tirkes T, Shah ZK, Takahashi N, Grajo JR, Chang ST, Venkatesh SK, Conwell DL, Fogel EL, Park W, Topazian M, Yadav D, Dasyam AK; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Reporting Standards for Chronic Pancreatitis by Using CT, MRI, and MR Cholangiopancreatography: The Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Radiology. 2019 Jan;290(1):207-215.


Hart PA, Andersen DK, Mather KJ, Castonguay AC, Bajaj M, Bellin MD, Bradley D, Contreras N, Habtezion A, Korc M, Kudva Y, Petrov MS, Whitcomb DC, Yadav D, Yuan Y, Rinaudo JAS, Srivastava S, Serrano J, Goodarzi MO; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1239-1243.

Fisher WE, Cruz-Monserrate Z, McElhany AL, Lesinski GB, Hart PA, Ghosh R, Van Buren G, Fishman DS, Rinaudo JAS, Serrano J, Srivastava S, Mace T, Topazian M, Feng Z, Yadav D, Pandol SJ, Hughes SJ, Liu RY, Lu E, Orr R, Whitcomb DC, Abouhamze AS, Steen H, Sellers ZM, Troendle DM, Uc A, Lowe ME, Conwell DL; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1213-1221.



Xiao AY, Tan ML, Plana MN, Yadav D, Zamora J, Petrov MS. The Use of International Classification of Diseases Codes to Identify Patients with Pancreatitis: A Systematic Review and Meta-analysis of Diagnostic Accuracy Studies. Clin Transl Gastroenterol. 2018 Oct 4;9(10):191.


Krishna SG, Kruger AJ, Patel N, Hinton A, Yadav D, Conwell DL. Cholecystectomy During Index Admission for Acute Biliary Pancreatitis Lowers 30-Day Readmission Rates. Pancreas. 2018 Sep;47(8):996-1002.

103



Hypertriglyceridemia and Pancreatitis. J Clin Gastroenterol. 2017 Jan;51(1):77-85.








Dhiraj Yadav, MD, MPHMuniraj T, Yadav D, Abberbock JN, Alkaade S, Amann ST, Anderson MA, Banks PA, Brand RE, Conwell D, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, Lewis MD, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Slivka A, Tang G, Whitcomb DC, Wilcox CM. Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis. Pancreatology. 2019 Jun;19(4):500-506.




Wu BU, Batech M, Dong EY, Duan L, Yadav D, Chen W. Influence of Ambulatory Triglyceride Levels on Risk of Recurrence in Patients with Hypertriglyceridemic Pancreatitis. Dig Dis Sci. 2019 Mar;64(3):890-897.

Tirkes T, Shah ZK, Takahashi N, Grajo JR, Chang ST, Venkatesh SK, Conwell DL, Fogel EL, Park W, Topazian M, Yadav D, Dasyam AK; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Reporting Standards for Chronic Pancreatitis by Using CT, MRI, and MR Cholangiopancreatography: The Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Radiology. 2019 Jan;290(1):207-215.


Hart PA, Andersen DK, Mather KJ, Castonguay AC, Bajaj M, Bellin MD, Bradley D, Contreras N, Habtezion A, Korc M, Kudva Y, Petrov MS, Whitcomb DC, Yadav D, Yuan Y, Rinaudo JAS, Srivastava S, Serrano J, Goodarzi MO; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1239-1243.

Fisher WE, Cruz-Monserrate Z, McElhany AL, Lesinski GB, Hart PA, Ghosh R, Van Buren G, Fishman DS, Rinaudo JAS, Serrano J, Srivastava S, Mace T, Topazian M, Feng Z, Yadav D, Pandol SJ, Hughes SJ, Liu RY, Lu E, Orr R, Whitcomb DC, Abouhamze AS, Steen H, Sellers ZM, Troendle DM, Uc A, Lowe ME, Conwell DL; Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC). Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec;47(10):1213-1221.



Xiao AY, Tan ML, Plana MN, Yadav D, Zamora J, Petrov MS. The Use of International Classification of Diseases Codes to Identify Patients with Pancreatitis: A Systematic Review and Meta-analysis of Diagnostic Accuracy Studies. Clin Transl Gastroenterol. 2018 Oct 4;9(10):191.


Krishna SG, Kruger AJ, Patel N, Hinton A, Yadav D, Conwell DL. Cholecystectomy During Index Admission for Acute Biliary Pancreatitis Lowers 30-Day Readmission Rates. Pancreas. 2018 Sep;47(8):996-1002.

104






Machicado JD, Chari ST, Timmons L, Tang G, Yadav D. A population-based evaluation of the natural history of chronic pancreatitis. Pancreatology. 2018 Jan;18(1):39-45.





Sue LY, Batech M, Yadav D, Pandol SJ, Blumentals WA, von Krusenstiern LS, Chen W, Wu BU. Effect of Serum Triglycerides on Clinical Outcomes in Acute Pancreatitis: Findings From a Regional Integrated Health Care System. Pancreas. 2017 Aug;46(7):874-879.



Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis

MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D. Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities. Am J Gastroenterol. 2017 Apr;112(4):633-642.

Han K, Li X, Bhargava R, Taylor S, Lee K, Yadav D. Polypoid Endometriosis Presenting as a Colonic Mass. ACG Case Rep J. 2017 Mar 15;4:e39.


Kamal A, Sinha A, Hutfless SM, Afghani E, Faghih M, Khashab MA, Lennon AM, Yadav D, Makary MA, Andersen DK, Kalloo AN, Singh VK. Hospital admission volume does not impact the in-hospital mortality of acute pancreatitis. HPB (Oxford). 2017 Jan;19(1):21-28.





Xiao AY, Tan ML, Wu LM, Asrani VM, Windsor JA, Yadav D, Petrov MS. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. Lancet Gastroenterol Hepatol. 2016 Sep;1(1):45-55.



Romagnuolo J, Talluri J, Kennard E, Sandhu BS, Sherman S, Cote GA, Al-Kaade S, Gardner TB, Gelrud A, Lewis MD, Forsmark CE, Guda NM, Conwell DL, Banks PA, Muniraj T, Wisniewski SR, Tian Y, Wilcox CM, Anderson MA, Brand RE, Slivka A, Whitcomb DC, Yadav D. Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women: Analysis of a Large Multicenter Cohort. Pancreas. 2016 Aug;

105






Machicado JD, Chari ST, Timmons L, Tang G, Yadav D. A population-based evaluation of the natural history of chronic pancreatitis. Pancreatology. 2018 Jan;18(1):39-45.





Sue LY, Batech M, Yadav D, Pandol SJ, Blumentals WA, von Krusenstiern LS, Chen W, Wu BU. Effect of Serum Triglycerides on Clinical Outcomes in Acute Pancreatitis: Findings From a Regional Integrated Health Care System. Pancreas. 2017 Aug;46(7):874-879.



Machicado JD, Amann ST, Anderson MA, Abberbock J, Sherman S, Conwell DL, Cote GA, Singh VK, Lewis

MD, Alkaade S, Sandhu BS, Guda NM, Muniraj T, Tang G, Baillie J, Brand RE, Gardner TB, Gelrud A, Forsmark CE, Banks PA, Slivka A, Wilcox CM, Whitcomb DC, Yadav D. Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities. Am J Gastroenterol. 2017 Apr;112(4):633-642.

Han K, Li X, Bhargava R, Taylor S, Lee K, Yadav D. Polypoid Endometriosis Presenting as a Colonic Mass. ACG Case Rep J. 2017 Mar 15;4:e39.


Kamal A, Sinha A, Hutfless SM, Afghani E, Faghih M, Khashab MA, Lennon AM, Yadav D, Makary MA, Andersen DK, Kalloo AN, Singh VK. Hospital admission volume does not impact the in-hospital mortality of acute pancreatitis. HPB (Oxford). 2017 Jan;19(1):21-28.





Xiao AY, Tan ML, Wu LM, Asrani VM, Windsor JA, Yadav D, Petrov MS. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. Lancet Gastroenterol Hepatol. 2016 Sep;1(1):45-55.



Romagnuolo J, Talluri J, Kennard E, Sandhu BS, Sherman S, Cote GA, Al-Kaade S, Gardner TB, Gelrud A, Lewis MD, Forsmark CE, Guda NM, Conwell DL, Banks PA, Muniraj T, Wisniewski SR, Tian Y, Wilcox CM, Anderson MA, Brand RE, Slivka A, Whitcomb DC, Yadav D. Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women: Analysis of a Large Multicenter Cohort. Pancreas. 2016 Aug;

106



45(7):934-40.


Munigala S, Yadav D. Case-fatality from acute pancreatitis is decreasing but its population mortality shows little change. Pancreatology. 2016 Jul-Aug;16(4):542-50.


ACKNOWLEDGMENTSThis report was produced by the Office of Academic Affairs in the Department of Medicine.

EXECUTIVE EDITORNichole Radulovich, MEd, CRAExecutive Administrator

SENIOR EDITOR, FACT-CHECKER, AND GRAPHIC DESIGNKatie NaumanAcademic Affairs Administrator

PROJECT COORDINATORSKristen BagwellWeb Producer

Jane-Ellen RobinetCommunications Coordinator

GASTROENTEROLOGY CONTENT MANAGERSJoy MerusiDirector, Digestive Health Programs

DATABASE DEVELOPMENT AND SUPPORTNemanja TomicDatabase Developer

Photo credits:All photos courtesy of the Division of Geriatric Medicine/Department of Medicine except page 7: Arne9001, Dreamstime stock photo ID 149502465; page 11 and 13: Google maps, “Gastro clinic locations,” accessed October 2019; and pages 21 and 39: Ted Przybocki, The Sherman Foundation

A special thank you to Claudia Kahn at the Sherman Foundation, who so graciously provided images of Sherman Prize winner, Dr. Binion.

107



45(7):934-40.


Munigala S, Yadav D. Case-fatality from acute pancreatitis is decreasing but its population mortality shows little change. Pancreatology. 2016 Jul-Aug;16(4):542-50.


ACKNOWLEDGMENTSThis report was produced by the Office of Academic Affairs in the Department of Medicine.

EXECUTIVE EDITORNichole Radulovich, MEd, CRAExecutive Administrator

SENIOR EDITOR, FACT-CHECKER, AND GRAPHIC DESIGNKatie NaumanAcademic Affairs Administrator

PROJECT COORDINATORSKristen BagwellWeb Producer

Jane-Ellen RobinetCommunications Coordinator

GASTROENTEROLOGY CONTENT MANAGERSJoy MerusiDirector, Digestive Health Programs

DATABASE DEVELOPMENT AND SUPPORTNemanja TomicDatabase Developer

Photo credits:All photos courtesy of the Division of Geriatric Medicine/Department of Medicine except page 7: Arne9001, Dreamstime stock photo ID 149502465; page 11 and 13: Google maps, “Gastro clinic locations,” accessed October 2019; and pages 21 and 39: Ted Przybocki, The Sherman Foundation

A special thank you to Claudia Kahn at the Sherman Foundation, who so graciously provided images of Sherman Prize winner, Dr. Binion.

108

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Division of Gastroenterology, Hepatology and Nutrition