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    Psychological Well Being

    and Health:

    Lessons from MIDUS

    Carol Ryff

    University of Wisconsin Madison

    Mediterranean Lifestyle, Well-Being, and Health Symposium

    School of Medicine, Pontificia Universidad Catlica

    Santiago, Chile, Tuesday, April 9, 2012

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    Ode to the:

    the tablethe chair

    the dog

    the gillyflower

    a bar of soap

    a pair of socks

    the dictionarybread

    the artichoke

    the onion

    the tomato

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    Outline of Presentation

    What is psychological well-being? Approaches: Hedonic & Eudaimonic

    How does well-being matter for health?

    Biological risk factors, morbidity, mortality(under conditions of challenge)

    Can well-being be promoted?

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    Philosophical Foundations

    of Well-Being

    Aristotle eudaimonia realization of true potential know thyself and become who you are

    Epicurus hedonia pleasure, happiness, contentment

    J. S. Mill utilitarianism

    happiness will not achieved if made an end in itselfby-product of other more noble deeds

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    Western preoccupations

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    (2010)

    Current preoccupations

    with happiness:

    advent of banality

    felicity and vacuity go

    hand in hand

    (Voltaires Candide)

    amiable twaddle of theDalai Lama

    it is better to lead a rich

    life with tears than a happy

    one without meaningthe defeat of an illusion

    always opens the door to

    miracles

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    purpose in life personal growth

    positive relations with others

    environmental mastery

    self-acceptance

    autonomy

    happiness/pos affect

    life satisfaction

    Defining Psychological Well-Being

    Eudaimonic(Ryff, 1989,J. of

    Pers. & Soc. Psych)

    Hedonic(Diener et al., 1999,

    Psych. Bulletin)

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    www.midus.wisc.edu

    http://www.midus.wisc.edu/http://www.midus.wisc.edu/
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    www.midus.wisc.edu

    MIDUS

    Data are

    publicly

    available,

    nopermissions

    required.

    Please use

    them!

    http://www.midus.wisc.edu/http://www.midus.wisc.edu/
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    Aging and Well-Being(evidence of vulnerabilities

    butsome individuals are resilient)

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    Source: MIDUS I

    25-39

    14.5

    15.0

    15.5

    16.0

    16.5

    17.0

    17.5

    18.0

    18.5

    Young Midlife Older40-59 60-74

    Purpose in Life

    Env. Mastery

    Positive Relations

    Autonomy

    Females

    Self-Acceptance

    Per. Growth

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    Purpose in Life

    Env. Mastery

    Positive Relations

    Autonomy

    Males

    Self-Acceptance

    Per. Growth

    14.5

    15.0

    15.5

    16.016.5

    17.0

    17.5

    18.0

    18.5

    Young Midlife Older25-39 40-59 60-74

    Source: MIDUS I

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    Longitudinal Decline (9-10 years)

    in Purpose in Life

    14

    15

    16

    17

    18

    T1 T2 T1 T2 T1 T2 T1 T2 T1 T2

    35-44 45-54 55-64 65-74 75-84

    Averaged

    summedscore

    Age at Time 2

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    Butsome older persons

    maintain high well-being.

    And, those who do show:reduced morbidity/mortality

    better sleep

    lower inflammatory factors

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    Purpose in life is protective against Alzheimers

    and mild cognitive impairment.

    (Boyle et al., Archives Gen Psychiatry, 2010)

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    Those with higher purpose in life live longer.

    (Boyle et al., Psychosom Med, 2009)

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    Purpose in life modifies association between Alzheimers

    disease pathology and cognitive function

    (Boyle et al.,Arch Gen Psych, 2012)

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    Those with higher purpose in life have reduced risk of stroke.

    (Kim et al.,J Psychosomatic Res, 2013)

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    High purpose in life reduces risk of myocardial infarction among

    adults with coronary heart disease

    (Kim et al.,J Behav Med, 2013)

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    Aging brings increased risk for poor sleep

    But older women

    with higher PWB

    have reducedrisk of disrupted

    sleep.

    Phelan et al., Psych and Aging, 2010

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    Aging bring increased risk for chronic conditions

    *such comorbidity fuels inflammation

    (Friedman & Ryff,J of Geront, 2012)

    But higher

    PWB

    protectsagainst such

    effects

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    As chronic conditions increase, higher well-being

    protects against elevated IL-6 and CRP.

    Friedman & Ryff,J of Ger, 2012

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    Educational Attainment

    and Well-Being

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    13

    14

    15

    16

    17

    18

    19

    20

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    Self-Acceptance

    Purpose in Life

    Environ. Mastery

    Positive Relations

    Personal Growth

    Autonomy

    Men

    13

    14

    15

    16

    17

    18

    19

    20

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    N=

    Psychological Well-Being and Education

    Five Number Summary

    Educational Level

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    Lower educational status higher levels of IL-6

    BUT effect is buffered by high psychological well-being

    Morozink et al., 2010

    Health Psychology

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    Lower educational attainment predicts

    higher levels of interleukin-6 (IL-6)

    Interleukin-6

    marker of inflammationinvolved in etiology of

    numerous diseases

    (cardiovascular, cancer,

    rheumatological,

    osteoporosis, Alzheimers)

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    BUT educational gradient

    in IL-6 is moderated by

    levels of psychological

    well-being :purpose in life

    positive relations

    environmental mastery

    self-acceptance

    positive affect

    (protective buffers)

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    High School, GED, or Less Education Some College Education Bachelors Degree or Higher

    0

    0,5

    1

    1,5

    2

    2,5

    3

    11 16 21 26 31 36 41 46

    SerumI

    L-6

    (pg/mL)

    Environmental Mastery

    * p < .05

    *

    Morozink et al., 2010

    Health Psychology

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    High School, GED, or Less Education Some College Education Bachelors Degree or Higher

    0

    0,5

    1

    1,5

    2

    2,5

    3

    14 19 24 29 34 39 44 49

    SerumIL

    -6(pg/mL)

    Purpose in Life

    * p < .05

    *

    Morozink et al., 2010

    Health Psychology

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    Resiliencecapacity to maintain or regain health

    and well-being in the face of

    challenge/adversity

    Ryff et al., (2012). Varieties of Resilience in MIDUS.

    Social and Personality Psychology Compass.

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    O ti i b tt li id fil

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    Optimism better lipid profiles

    Boehm et al., (2013),Am J of Cardiology

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    Optimism higher levels of antioxidants

    Boehm et al. (2013), Psychosomatic Medicine

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    Neuroscience of

    Well-Being

    F t l f i f

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    Van Reekum et al., 2007,J of Cognitive Neuroscience

    Faster eval of neg info:

    greater amyg activ

    However, higher PWB:

    slower eval neg info

    lower amyg activ

    increased activation of

    anterior cingulate cortex

    Neuroimaging study

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    These findings suggest that people high in PWBeffectively recruit the ventral ACC when confronted

    with potentially aversive stimuli, manifest reduced

    activity in subcortical regions such as the

    amygdala, and appraise such information as lesssalient as reflected in slower evaluative speed.

    Van Reekum et al., 2007,

    J of Cognitive Neuroscience

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    Eudaimonic well-being is positively associated with

    insular cortex volume (Lewis et al., 2013)

    Higher well-being linked with sustained ventral striatal

    activity and lower cortisol output (Heller et al., 2013)Those who show repeated engagement of reward circuitry

    when responding to multi-valenced stimuli have higher PWB

    and better regulation of HPA activity

    New Neuroscience Findings

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    among those who most need it(those suffering from depression)

    well-being therapyFava et al. (1998)

    Archives of General Psychiatry

    importance of well-being in recovery

    process

    Promoting Well-Being

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    From Treatment to Prevention

    Teaching well-being therapy tochildren and adolescents

    Ruini et al. (2006)

    Psychother & Psychosom

    Ruini et al. (2009)

    J of Behav TherapyTombe et al. (2010)

    J of Anxiety

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    Conclusions Prior health research

    has been blind tohuman resilience (HR)

    HR is a hugely

    important, empirically

    tractable topic HR appears to be

    consequential for health

    HR can be promoted

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    Thanks!

    My email: [email protected]

    http://midus.wisc.edu

    http://midus.wisc.edu/http://midus.wisc.edu/
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