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8/12/2019 Idoc.vn Duoc Lieu Chua Alcaloid Co Nhan Indol
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Gio vin hng dn :NGUYN TH HOI
Sinh vin:L Th Trang Trn Th i!n Trn "#n H$%nh
"& '() *+ng Ng$,!n "#n -$,./ Ho0ng Th Thanh Th1o 2h34 H5$ To0n *h6$7
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DC LIU CHADC LIU CHA
ALCALOID CALCALOID CNHN INDOLNHN INDOL
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C IM THC VT
*6, g>? /h@ng A(ng?)ao BCDE4 L 4) AFi?hnh /r(ng A$ nhn?
4/ /rn anh JKng?4/ di )KB g6n
hnh )$ng ni rM *4 hoa hnh ng?4) P A$
)0nh
-$1 /h/?hnh )$?vQ nhRn JKng?
9hi )hn 40$ v0ng )a4?)h(a DCBh3/
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H3/:
Hnh Aa d/? hVi d0, WnP 4X? 4Z/ [F h3/ hVi
4Xo 4K? )ong? vnh9h\ng A=$? A+ng 9nhD?EC E?B )4? d0, ]?^C ]?_)4? hVi JKng? 40$ 4nh3/ A.n v0ng nh3/7
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8 ;a hoa: /hng ` C ^8 ;a $1: /hng B C b
8 2h6n JF:cn 'Z? Sri Lan9a?
;aWa,[ia? Thi Lan? e)f$[/raWia? 4) hoang Prng n$i) )) /nh hana4 n) /a7
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MT S LOI M TIN DY LOTHN !" #H$C
8 Strychnos vanprukii*raiJj S.quadrangularisHiWW7?S7ni/ida Gagnk7l : ;< /i=n )0nh v$\ng7
8 Strychnos ignatiikrgi$[j S. hainanensis;krr7k/ *h$nl:*6, Am$ giK7
8 Strychnos axillaris*oWkJr: ;< /i=n hoa n)h7
8 Strychnos umbellataLo$r7l ;krr: ;< /i=n hoa /n7
8 Strychnos cathayensis;krr: ;< /i=n Tr$ng -$F)?;< /i=n
*/ H1i7
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THU H$I V CH% &I%N
Th$ hi:Th+ng / nh5ng $1 )hn rng $Fng W04 h3/ /$ng raha, do )hi4 #n $1 JQ W3i h3/ di gF) )6,7
C Z hmn dng: H3/? /h+ng A) )h. Ji.n /r) 9hidng7
*h. Ji.n: Ng64 n) vo g3o? )3o vQ? /hi? [p, 9h\? /q4 d$
vng? [ao v0ng Am47'$n [\i /rong d$ vng? /hi nhQ? [p, 9h\7
Ng64 n) vo g3o? v/ ra? np$ vi )a4 /h1o? JK) vQ?A$n d$ vng? /hi nhQ? [p, 9h\7
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THNH 'H(N HA H)C
CfW)aWoid: ECB? B] W0 [/r,)hnin?)sn W3i W0 Jr$)in?tC)$WoJrin? uC )$WoJrin777
S/r,)hninDj Ej C Hr$)in Dj Ej C O*H`
tC)$WoJrin Dj C H w Ej C O*H`7
uC )$WoJrin Dj C O*H`w Ej C H
CNgo0i ra )sn )K:? a)id h5$ )V?)hp/ JXo77
C L? vQ $1 )h(a aW)aWoid ECb )hx ,.$ W0 Jr$)in
N
R1
R1
O O
N
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#IM N!HIM*+, -.+,/
D7 Trn vi h$:E7 'nh /nh [/r,)hnin v0 Jr$)in /rong JZ/ d) Wiy$ S/r,)hnin: // ;andkWin: $p/ hiyn 40$ anh )h$,zn dn [ang /4
AQ7
r$)in: HNO`AA: 40$ AQ )h$,zn dn [ang v0ng // {rd4ann HESO^| HNO`AAl: 40$ h}ng
)h$,zn nhanh [ang v0ng7 S~L;? AFi )hi.$ vi )hp/ )h$qn7
*+, 012+3/C 2hVng h a)idCJa[k? Ao $ang? [o 40$7
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T$C D4N! DC L5'Fi vi /hn 9inh T v0 ngo3i vi:
Li=$ nhQ: 9)h /h)h7 Li=$ )ao: g6, )o gim/7
'Fi vi /i4 v0 hy /$n ho0n: L04 /#ng h$,./ do W04 )o 43)h 4$ ngo3i vi7S/r,)hnin W0 )hp/ 9)h /h)h /i4
'Fi vi d3 d0, v0 JZ 4, /i$ hKa:T#ng /i./ d)h v? 9)h /h)h /i$ hKa7ng nhi=$ [ g6, rFi Wo3n /i$ hKa? rFi Wo3n )o JK
d3 d0,7
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C T5NH
;< /i=n rp/ AZ)7( M tin sng thu!c nh"m thu!c #!c b$ng %& M tin ch' thu!c
nh"m thuc #!c b$ng ).
NL: UFng D Wn BCE]4g[/r,)hnin J /rng AZ)7
Wi=$ _]C]4g [/r,)hnin)K /hz g6, / vong do Wiy/ h\ hp
/hko /0i Wiy$ , v#n ) /h dng h3/ 4< /i=n g6, / vong7l
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IU HIN NG '*:
Ng
T#ng /i./ n) J/? n\n 4a
S nh [ng?43)h nhanh v0 ,.$? *h6n /a, )(ng A+? )o gim/ nh? W}i 4e/? A}ng
/ 4P rZng e /h/ )o /he/ g6, 9hK /hP? [a$
)h./ v Wiy/ h\ hp7
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67 T85 #HI &9 N! C M TIN
a d3 d0, [4?UFng /han ho3/ /nh?
*hFng ng3/ /hP?
Tr$,=n d)h?
UFng /h$F) an /hn?
N.$ nng )n 9hqn /rVng Aa Wn /$,.n/rn7
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C:N! D4N! ; LIU LN!
;< /i=n W0 ng$,n Wiy$ )hi./ $p/ [/r,)hnin78 T Wiy/ d6, /hn 9inh8 [$, nh) )V n#ng
8 Liy/ dVng8 ~)h /h)h h0nh /x,
UFng: ]?]]DgWn ]?]]`gE^hl
Ti4 di da: ]?]]DgWn ]?]]EgE^hl
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8 ;< /i=n [Fng:L04 /h$F) oa JK j nh() 4Qi /a, )h6n
ng d3ng )}n /h$F) ha, hFi h vi \ A$? h/7
8 ;< /i=n )h.:
*h5a Aa$ nh()? [ng 9h? /i$ hKa 9X4? [$,nh) /hn 9inh? J3i Wiy/? Wiy/ na ng+i? )hK d3i)en7
Li=$ $Fng /Fi Aa: ]?DgWn ]?`gE^hlTr k4 di ` /$i 9h\ng A) dng
` /$i: dng ]?]]Bg )ho 4>i /$i
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MT S CH% 'H /rng7777777777777777D_4g
8 Ng$ /p/777777777777777D^ 4g8 -$. )hi77777777777777777]b 4g
8 ThVng /r$m/77777777777D_ 4g
8 'Z) ho3/777777777777777777D_ 4g
8 Th h) Winh777E^ 4g
8 T d)777777777777777vA D vin
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T,=+, >,?+ /
8 A$?
8 ;k/h,W [aWi),Wa/?
8 ;< /i=n?8 Thin nin 9iyn?
8 -$.? H}i?
8 H$,./ gi)?
8 /inh d$ Wong n
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8'i=$ /r
*) )h(ng Aa$ d6, /hn
9inh Win [+n? Aa$ vai?g,? Aa$ )) )hi? Aa$
Wng? Aa$ nh() )) 9h7
8*\ng /h()
;< /i=n )h.(Semen Strychmin praeparatum) ]?4g S/r,)hnin
H, /hi4 (*erba Siegesbechia) bBE 4gNg& gia J (+ortex Sche,,lerae octophyllae) 7777777777777777777E`E 4gTa4 /hp/ (adix seudaginseug)7777777777777777777777777777777777777 B] 4gT d) va Ax D vin
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8 Th0nh hn:
Z/ 4< /i=n )h.]?]D`g
H, /hi47]?]`gNg& gia J]?]]Bg
*ao ng& gia J]?]`Bg
8 *\ng dng :
'i=$ /r vi4 Aa 9h d3ng /hp?Aa$ nh() Vng 9h? Aa$
d6, /hn 9inh /a? /hn 9inhWin [+n? Aa$ Wng? Aa$ vaig,7
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MT S &I THUC :N! Y8 *h5a hong /hp? / Wiy/ na ng+i:H3/ 4< /i=n
np$ vi d$ vng )ho A.n 9hi d$ng d)h )K 40$v0ng7 "/ h3/ Am nhQ? /n JZ/? 4>i Wn $Fng ]?Dg7UFng A.n 9hi ra 4} h\i /h /h\i7
8 "i4 3i Wiy/ /r k4:;< /i=n / [ao )/l? $,n /%gi1i? Ng$ /p/? ;Z) $a? 0 nh)? T) Aan? Ng\)\ng? 64 dVng hoe) )h)hl? 'Vng $i? Nh)/h$ng d$ng? ~i4 4ao )q$ /)h? /) )F/ A=$ `]g?
ThQ /, /? *Vng /04 _]g? )) Wo3i /h$F) /n JZ/4n7 64 dVng hoe) [e) n) hsa JZ/ /rZn W04ho0n7 ;>i Wn $Fng ]?` C D?] )V /hz ,.$ gi14 Wi=$l?ng0, ` Wn vi n) [\i p47
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8 Tr )h6n /a, ,.$? )V /hz [$, nh):'1ng [64? 3)h /r$m/ A=$
_]g? ;< /i=n )h.? 'Vng $i? Nh& hVng? ;Z/ d)? $,n [Vngi A=$ `]g? Ng\ )\ng B )on? /n JZ/ 4n hsa 4m/ W04 vinJng h3/ A> anh? 4>i Wn $Fng E C ^g? ng0, E Wn vi r$ p47
8 ~in h ho0n/r )) )h(ng Aa$ 9h do hong /hp? Aa$ Wng?Aa$ )nh /a,? )h(ng / d3i /o0n /h6n ho) 9h$ /rl*h. ;< /i=n/? *h. $,n \? *h. /h1o \? ~hVng ho3/? 'Z) ho3/ 4>i /h(E]]g? )h. 2h / ^]g? *h. Nh& hVng? *h. ;Z/ d) A=$ b]g?To0n 'Vng $i? Ng$ /p/? ;a ho0ng? ;Z) $a A=$ D]g7 Tn
JZ/ 4n? dng -$. )hi _]g [e) n) W04 ho0n Jng h3/ A>anh7 UFng p4 /r) 9hi ngx vi n) [\i p4? 4>i Wn ` C ^gn$F/7
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HONG NN
8 Tn 9h):Ho0ng A0n? "Qdo
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C IM CY
8 *6, nh 4) Wko? /h6n g>? )0nh )K /$a )$Fn v0 4K))(ng nh [ng7
8 "Q /h6n 4? )K nF/ [n [i 40$ n6$ AQ
8 L 4) AFi? nhRn? )K ` g6n nh\ Wn P 4/ )hnh diW7
8 Hoa 9h\ng )$Fng? 4) /h0nh )h,? d3ng ng P A$)0nh? hx W\ng 40$ h$ng n6$7
8 -$1 4ng? hnh )$? vQ $1 )(ng? d! v78 H3/ nhi=$? hnh )) o? )K W\ng 4/ v0ng nh J3)7
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8 &@ >,+ B+3/ "Q /h6n hVi ha, [p, 9h\
8 ',+ EF/;Z/ [F /nh ha e)? nh:T$,n -$ang? "nh h
L3ng [Vn? Ho0 nh? Nghyfn? Thanh HKa7
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THU H$I V CH% &I%N
8 Th$ hi:Ng+i /a /h+ng JK) vQ /h6n ha, vQ )0nh Ak4 hVi 9h\7
8 *h. Ji.n:
Ng64 vQ v0o n) /rong DECE^h? )3o h./ W v0ng Jnngo0i r}i ng64 n) vo g3o ` ng0, A4 4>i ng0, /ha,n) g3o 4Z/ Wnl7 a [3)h? /hi nhQ? hVi ha, [p,9h\? Ang /rong W 9n7 Tr) 9hi dng Ak4 [ao $a?
nghi=n /n /h0nh JZ/7 *K ng+i /r) 9hi /n JZ/ W3i /q4vi d$ vng [ao $a7
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THNH 'H(N HA H)C
C"Q /h6n )h(a: aW)aWoid /o0n hn B?E`?
| [/r,)hnin E?` C E?^`?
| Jr$)in E?bD7C Nha
5
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9NH T5NH
C NhQ HNO` Wn 4/ /rong )xa vQ [ $p/ hin 40$ AQ4$7NhQ Wn 4/ ngo0i /rn nh5ng nF/ [nl $p/ hiyn40$ W) Akn nh3/7
C Le) Dg JZ/ dW | D]4W *H`*W | D4W NH` /rong B h/7L)W *H`*W $a gip, W) )K NaESO^9han7*hia d)h W) W04E r}i Ak4 JF hVi /rn n}i ))h /hx, A.n 9h\7
| ng D: Hsa )en /rong EC` gi/ HESO^AA?/h4 v0i // 9aWi
Ji)ro4a/ [ $p/ hiyn 40$ /4 4p/ nhanh [/r,)hninl7 | ng E: Th4 v0o )en EC` gi/ HNO` AA [ $p/ hiyn
40$ AQ Jr$)inl7
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C:N! D4N! V LIU DGN!
8 p/ AZ) vQ v0 h3/ )h(a )hp/ )) AZ) /h$Z) J1ng fl?h1i )h. /r) 9hi dng7
8 *h5a )hK d3i )en? )h5a hxi? gh? v0 Jynh ngo0i da9hK )h5a7
8 *h5a /hp 9h? )+ng dVng?9)h /h)h [inh d)n57
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F
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8 ',1+3 -,JFK -* K,+3 ,=+ -,> RPJ +,K W@-K,X) Wiy$: Ho0ng n0n )h. 9 E]]g? h$,./ gi) D_]g?
/hin nin 9iyn D_]g? hVng h )h. DE]g? 4Z) hVngna4 DE]g? /hVng /r$m/ [ao b]g? $. /h\ng $. )hil^]g7
*h. Ji.n v0 ))h dng:*) v [ao 9? /n /h0nh JZ/ 4n)ho h} vin ho0n /o Jng h3/ Am$ anh? [p, 9h\ )p/ [dng dn7 Ng+i Wn $Fng 4>i Wn D] vin /r) 9hi #n Dgi+7 TFi W3i $Fng /i. D] vin /r) 9hi Ai ngx7
L$ : Sa$ 4>i Wn $Fng /h$F) nn $Fng D )F) nhQ r$
/reng Az dn /h$F) nhanh hVn7 ~hi $Fng nh Ang nhai40 n$F/ W$\n )1 vin7
*hFng )h Anh:)) ng+i 4e) )h(ng hong /hp /hznhiy/ 9h\ng A) [ dng hVng n0,7
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8 *h5a ren? )hK d3i )en :a $a 4i.ng vQ ho0ng n0n?[p, 9h\ /n JZ/? dng hFi h vi 3)h h0n? Hngho0ng
8 *h5a hong / /hp ) Wiy$: Ho0ng n0n _]]gr? HVng h / )h.
D_]gr? Th1o $1 [Fngl JQ vQ Wp, h3/ E]gr? '3i h}i JQh3/l E]gr7
*)h dng: Tn JZ/? $Fng [a$ 9hi #n na gi+ EC`gr vin) ho) $? n.$ )K h1n (ng gi14 W$i7 Ng+i h$,./ )ao 9h\ng dng7 Sa$ 9hi $Fng /h n4? dng Az )h5anh() Vng Aa$ A$ gFi? / /hp7 *K 9hi $Fng v0o
)h$,zn Aa$ hVn nhng [a$ AK W3i 9hQi ~inh Nghiy4 6nGianl7