Retinitis Pigmentosa JACKSON, JEFFERSON, KLECKA, CASTILLO

Retinitis Pigementosa (RP)

RP refers to a group of inherited disease causing retinal degeneration.

Retinal degeneration

Symptoms

Decreased vision or in low light

Loss of side (peripheral) vision, causing “tunnel vision”

Loss of central vision (in advanced cases)

Decreased vision at night

Peripheral vision

Loss of central vision

Causes

RP can run in families

Disorder can be caused by genetic defects

Cells controlling night vision are called “rods”

Retinal cone cells are damaged the most

Exams and test

Color vision

Retina by ophthalmoscopy after pupils been dilated

Fluorescein angiography

Intraocular pressure

Measurement of electrical activity (electroretinogram)

Pupil reflex test

Retinal photography

Refraction test

Retinal Photography

Side vision test (visual field test)

Slit lam examination

Visual acuity

Treatments

Gene Therapy

Stem cell research

Eye implants

Pharmacology and medicines

Docosahexaenoic acid (DHA)

Vitamin A antioxidants

Genetic mutations that could cause RP

Autosomal recessive

Autosomal dominant

X linked